Primary Site >> Liver Cancer

Gene >> SLC22A1

Journal: J Pharmacol Exp Ther. 2006 Nov;319(2):809-17.
Title: Molecular determinants in the transport of a bile acid-derived diagnostic agent in tumoral and nontumoral cell lines of human liver.
Author: Libra, Antonin|Fernetti, Cristina|Lorusso, Vito|Visigalli, Massimo|Anelli, Pier Lucio|Staud, Frantisek|Tiribelli, Claudio|Pascolo, Lorella
PMID: 16895978
Journal: Genome Med. 2011 Dec 23;3(12):82.
Title: DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma.
Author: Schaeffeler, Elke|Hellerbrand, Claus|Nies, Anne T|Winter, Stefan|Kruck, Stephan|Hofmann, Ute|van der Kuip, Heiko|Zanger, Ulrich M|Koepsell, Hermann|Schwab, Matthias
PMID: 22196450
Journal: Genome Med. 2012 Jan 31;4(1):10.
Title: Drug transporter regulation in tumors by DNA methylation.
Author: Zolk, Oliver|Fromm, Martin F
PMID: 22293136
Journal: BMC Cancer. 2012 Mar 22;12:109.
Title: Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance.
Author: Heise, Michael|Lautem, Anja|Knapstein, Johanna|Schattenberg, Jorn M|Hoppe-Lotichius, Maria|Foltys, Daniel|Weiler, Nina|Zimmermann, Anca|Schad, Arno|Grundemann, Dirk|Otto, Gerd|Galle, Peter R|Schuchmann, Marcus|Zimmermann, Tim
PMID: 22439694
Journal: Mol Pharm. 2012 Jun 4;9(6):1693-704.
Title: No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.
Author: Martinez-Becerra, P|Vaquero, J|Romero, M R|Lozano, E|Anadon, C|Macias, R I R|Serrano, M A|Grane-Boladeras, N|Munoz-Bellvis, L|Alvarez, L|Sangro, B|Pastor-Anglada, M|Marin, J J G
PMID: 22524153
Journal: Drug Metab Dispos. 2013 Jun;41(6):1179-86.
Title: Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites.
Author: Swift, Brandon|Nebot, Noelia|Lee, Jin Kyung|Han, Tianxiang|Proctor, William R|Thakker, Dhiren R|Lang, Dieter|Radtke, Martin|Gnoth, Mark J|Brouwer, Kim L R
PMID: 23482500
Journal: Hepatology. 2013 Sep;58(3):1065-73.
Title: Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.
Author: Herraez, Elisa|Lozano, Elisa|Macias, Rocio I R|Vaquero, Javier|Bujanda, Luis|Banales, Jesus M|Marin, Jose J G|Briz, Oscar
PMID: 23532667
Journal: Biomed Res Int. 2013;2013:692071.
Title: Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.
Author: Lozano, Elisa|Herraez, Elisa|Briz, Oscar|Robledo, Virginia S|Hernandez-Iglesias, Jorge|Gonzalez-Hernandez, Ana|Marin, Jose J G
PMID: 23984399
Journal: Drug Metab Dispos. 2014 Dec;42(12):2033-40.
Title: Differential expression of drug uptake and efflux transporters in Japanese patients with hepatocellular carcinoma.
Author: Namisaki, Tadashi|Schaeffeler, Elke|Fukui, Hiroshi|Yoshiji, Hitoshi|Nakajima, Yoshiyuki|Fritz, Peter|Schwab, Matthias|Nies, Anne T
PMID: 25231932
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Oct;35(10):1417-21.
Title: [Low expression of SLC22A1 is associated with a poor prognosis of hepatocellular carcinoma: analysis of 303 patients].
Author: Wang, Shu-Tong|Shen, Shun-Li|Hua, Yun-Peng|Chen, Bin|Kuang, Ming|Li, Shao-Qiang|He, Qiang|Peng, Bao-Gang
PMID: 26547334
Journal: BMC Cancer. 2016 Feb 12;16:94.
Title: Organic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatment.
Author: Grimm, Daniel|Lieb, Jonas|Weyer, Veronika|Vollmar, Johanna|Darstein, Felix|Lautem, Anja|Hoppe-Lotichius, Maria|Koch, Sandra|Schad, Arno|Schattenberg, Jorn M|Worns, Marcus A|Weinmann, Arndt|Galle, Peter R|Zimmermann, Tim
PMID: 26872727
Journal: Pharmaceutics. 2016 Dec 28;9(1). pii: pharmaceutics9010003.
Title: Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.
Author: Jouan, Elodie|Le Vee, Marc|Denizot, Claire|Parmentier, Yannick|Fardel, Olivier
PMID: 28036031
Journal: Oncotarget. 2017 Feb 28;8(9):15846-15857.
Title: The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma.
Author: Geier, Andreas|Macias, Rocio I R|Bettinger, Dominik|Weiss, Johannes|Bantel, Heike|Jahn, Daniel|Al-Abdulla, Ruba|Marin, Jose J G
PMID: 28178663
Journal: Br J Cancer. 2017 Sep 26;117(7):965-973.
Title: Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
Author: Levi, Francis|Karaboue, Abdoulaye|Saffroy, Raphael|Desterke, Christophe|Boige, Valerie|Smith, Denis|Hebbar, Mohamed|Innominato, Pasquale|Taieb, Julien|Carvalho, Carlos|Guimbaud, Rosine|Focan, Christian|Bouchahda, Mohamed|Adam, Rene|Ducreux, Michel|Milano,
PMID: 28817838
Journal: Oncol Lett. 2017 Oct;14(4):3975-3980.
Title: Screening the key genes of hepatocellular adenoma via microarray analysis of DNA expression and methylation profiles.
Author: Liu, Dan|Liu, Pengfei|Cao, Liye|Zhang, Quan|Chen, Yaqing
PMID: 28943905