Primary Site >> Colorectal Cancer

Gene >> SLC11A2

Journal: Gut. 2006 Oct;55(10):1449-60. Epub 2006 Apr 26.
Title: Modulation of iron transport proteins in human colorectal carcinogenesis.
Author: Brookes, M J|Hughes, S|Turner, F E|Reynolds, G|Sharma, N|Ismail, T|Berx, G|McKie, A T|Hotchin, N|Anderson, G J|Iqbal, T|Tselepis, C
PMID: 16641131
Journal: PLoS One. 2013 Nov 6;8(11):e78850.
Title: Dietary iron enhances colonic inflammation and IL-6/IL-11-Stat3 signaling promoting colonic tumor development in mice.
Author: Chua, Anita C G|Klopcic, Borut R S|Ho, Desiree S|Fu, S Kristine|Forrest, Cynthia H|Croft, Kevin D|Olynyk, John K|Lawrance, Ian C|Trinder, Debbie
PMID: 24223168
Journal: Nanomedicine (Lond). 2015 Jan;10(1):35-55.
Title: Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc.
Author: Kanwar, Jagat R|Mahidhara, Ganesh|Roy, Kislay|Sasidharan, Sreenivasan|Krishnakumar, Subramanian|Prasad, Neerati|Sehgal, Rakesh|Kanwar, Rupinder K
PMID: 25017148
Journal: Biochem Pharmacol. 2015 Aug 1;96(3):216-24.
Title: Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2.
Author: Montalbetti, Nicolas|Simonin, Alexandre|Simonin, Celine|Awale, Mahendra|Reymond, Jean-Louis|Hediger, Matthias A
PMID: 26047847
Journal: Cell Metab. 2016 Sep 13;24(3):447-461.
Title: Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.
Author: Xue, Xiang|Ramakrishnan, Sadeesh K|Weisz, Kevin|Triner, Daniel|Xie, Liwei|Attili, Durga|Pant, Asha|Gyorffy, Balazs|Zhan, Mingkun|Carter-Su, Christin|Hardiman, Karin M|Wang, Thomas D|Dame, Michael K|Varani, James|Brenner, Dean|Fearon, Eric R|Shah, Yatrik M
PMID: 27546461
Journal: Metallomics. 2017 Oct 18;9(10):1389-1393.
Title: Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells.
Author: Schlottmann, F|Vera-Aviles, M|Latunde-Dada, G O
PMID: 28937159