Primary Site >> Colorectal Cancer

Gene >> ROS1

Journal: Br J Cancer. 2003 Jan 27;88(2):314-9.
Title: Degree of tumour vascularity correlates with drug accumulation and tumour response upon TNF-alpha-based isolated hepatic perfusion.
Author: van Etten, B|de Vries, M R|van IJken, M G A|Lans, T E|Guetens, G|Ambagtsheer, G|van Tiel, S T|de Boeck, G|de Bruijn, E A|Eggermont, A M M|ten Hagen, T L M
PMID: 12610519
Journal: Cancer. 2013 May 1;119(9):1627-35.
Title: Identification of ROS1 rearrangement in gastric adenocarcinoma.
Author: Lee, Jeeyun|Lee, Seung Eun|Kang, So Young|Do, In-Gu|Lee, Sujin|Ha, Sang Yun|Cho, Jeonghee|Kang, Won Ki|Jang, Jiryeon|Ou, Sai-Hong Ignatius|Kim, Kyoung-Mee
PMID: 23400546
Journal: PLoS Genet. 2013 Apr;9(4):e1003464.
Title: Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.
Author: Giacomini, Craig P|Sun, Steven|Varma, Sushama|Shain, A Hunter|Giacomini, Marilyn M|Balagtas, Jay|Sweeney, Robert T|Lai, Everett|Del Vecchio, Catherine A|Forster, Andrew D|Clarke, Nicole|Montgomery, Kelli D|Zhu, Shirley|Wong, Albert J|van de Rijn, Matt|Wes
PMID: 23637631
Journal: Clin Cancer Res. 2013 Aug 1;19(15):4040-5.
Title: Molecular pathways: ROS1 fusion proteins in cancer.
Author: Davies, Kurtis D|Doebele, Robert C
PMID: 23719267
Journal: Mol Cancer Res. 2014 Jan;12(1):111-8.
Title: ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Author: Aisner, Dara L|Nguyen, Teresa T|Paskulin, Diego D|Le, Anh T|Haney, Jerry|Schulte, Nathan|Chionh, Fiona|Hardingham, Jenny|Mariadason, John|Tebbutt, Niall|Doebele, Robert C|Weickhardt, Andrew J|Varella-Garcia, Marileila
PMID: 24296758
Journal: Acta Neuropathol. 2014 Dec;128(6):879-91.
Title: Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.
Author: Berghoff, Anna Sophie|Bartsch, Rupert|Wohrer, Adelheid|Streubel, Berthold|Birner, Peter|Kros, Johan M|Brastianos, Priscilla K|von Deimling, Andreas|Preusser, Matthias
PMID: 25287912
Journal: Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2965-70.
Title: Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type.
Author: Gatalica, Zoran|Snyder, Carrie|Maney, Todd|Ghazalpour, Anatole|Holterman, Daniel A|Xiao, Nianqing|Overberg, Peggy|Rose, Inga|Basu, Gargi D|Vranic, Semir|Lynch, Henry T|Von Hoff, Daniel D|Hamid, Omid
PMID: 25392179
Journal: Br J Cancer. 2015 Dec 22;113(12):1730-4.
Title: Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer.
Author: Amatu, Alessio|Somaschini, Alessio|Cerea, Giulio|Bosotti, Roberta|Valtorta, Emanuele|Buonandi, Pasquale|Marrapese, Giovanna|Veronese, Silvio|Luo, David|Hornby, Zachary|Multani, Pratik|Murphy, Danielle|Shoemaker, Robert|Lauricella, Calogero|Giannetta, Laur
PMID: 26633560
Journal: Expert Opin Investig Drugs. 2015;24(11):1493-500.
Title: Entrectinib: a potent new TRK, ROS1, and ALK inhibitor.
Author: Rolfo, Christian|Ruiz, Rossana|Giovannetti, Elisa|Gil-Bazo, Ignacio|Russo, Antonio|Passiglia, Francesco|Giallombardo, Marco|Peeters, Marc|Raez, Luis
PMID: 26457764
Journal: Cancer Gene Ther. 2015 Sep;22(9):417-30.
Title: A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.
Author: Dietel, M|Johrens, K|Laffert, M V|Hummel, M|Blaker, H|Pfitzner, B M|Lehmann, A|Denkert, C|Darb-Esfahani, S|Lenze, D|Heppner, F L|Koch, A|Sers, C|Klauschen, F|Anagnostopoulos, I
PMID: 26358176
Journal: Cancer Genet. 2015 Jan-Feb;208(1-2):35-40.
Title: Systematic search for rare variants in Finnish early-onset colorectal cancer patients.
Author: Tanskanen, Tomas|Gylfe, Alexandra E|Katainen, Riku|Taipale, Minna|Renkonen-Sinisalo, Laura|Jarvinen, Heikki|Mecklin, Jukka-Pekka|Bohm, Jan|Kilpivaara, Outi|Pitkanen, Esa|Palin, Kimmo|Vahteristo, Pia|Tuupanen, Sari|Aaltonen, Lauri A
PMID: 25749350
Journal: Appl Immunohistochem Mol Morphol. 2015 Feb;23(2):134-8.
Title: ALK and ROS1 overexpression is very rare in colorectal adenocarcinoma.
Author: Houang, Michelle|Toon, Christopher W|Clarkson, Adele|Sioson, Loretta|de Silva, Keshani|Watson, Nicole|Singh, Nisha R|Chou, Angela|Gill, Anthony J
PMID: 24992173
Journal: Curr Med Chem. 2016;23(2):142-60.
Title: ROS1 Kinase Inhibitors for Molecular-Targeted Therapies.
Author: Al-Sanea, M M|Abdelazem, A Z|Park, B S|Yoo, K H|Sim, T|Kwon, Y J|Lee, S H
PMID: 26438251
Journal: Mol Cancer Ther. 2016 Apr;15(4):628-39.
Title: Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications.
Author: Ardini, Elena|Menichincheri, Maria|Banfi, Patrizia|Bosotti, Roberta|De Ponti, Cristina|Pulci, Romana|Ballinari, Dario|Ciomei, Marina|Texido, Gemma|Degrassi, Anna|Avanzi, Nilla|Amboldi, Nadia|Saccardo, Maria Beatrice|Casero, Daniele|Orsini, Paolo|Bandiera,
PMID: 26939704
Journal: Cancer Discov. 2017 Apr;7(4):400-409.
Title: Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).
Author: Drilon, Alexander|Siena, Salvatore|Ou, Sai-Hong Ignatius|Patel, Manish|Ahn, Myung Ju|Lee, Jeeyun|Bauer, Todd M|Farago, Anna F|Wheler, Jennifer J|Liu, Stephen V|Doebele, Robert|Giannetta, Laura|Cerea, Giulio|Marrapese, Giovanna|Schirru, Michele|Amatu, Ales
PMID: 28183697
Journal: Pharmacol Res. 2017 Jul;121:202-212.
Title: ROS1 protein-tyrosine kinase inhibitors in the treatment of ROS1 fusion protein-driven non-small cell lung cancers.
Author: Roskoski, Robert Jr
PMID: 28465216
Journal: Oncotarget. 2017 Jul 24;8(33):55353-55360.
Title: Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient.
Author: Milione, Massimo|Ardini, Elena|Christiansen, Jason|Valtorta, Emanuele|Veronese, Silvio|Bosotti, Roberta|Pellegrinelli, Alessio|Testi, Adele|Pietrantonio, Filippo|Fuca, Giovanni|Wei, Ge|Murphy, Danielle|Siena, Salvatore|Isacchi, Antonella|De Braud, Filippo
PMID: 28903424
Journal: J Clin Pathol. 2017 Dec;70(12):1001-1009.
Title: ROS1-1.
Author: Pal, Prodipto|Khan, Zanobia
PMID: 28903995
Journal: J Natl Cancer Inst. 2017 Dec 1;109(12). pii: 3860155.
Title: ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.
Author: Pietrantonio, Filippo|Di Nicolantonio, Federica|Schrock, Alexa B|Lee, Jeeyun|Tejpar, Sabine|Sartore-Bianchi, Andrea|Hechtman, Jaclyn F|Christiansen, Jason|Novara, Luca|Tebbutt, Niall|Fuca, Giovanni|Antoniotti, Carlotta|Kim, Seung Tae|Murphy, Danielle|Bere
PMID: 29370427
Journal: Am J Hematol. 2018 May;93(5):607-614.
Title: Long-term effects of crizotinib in ALK-positive tumors (excluding NSCLC): A phase 1b open-label study.
Author: Gambacorti-Passerini, Carlo|Orlov, Sergey|Zhang, Li|Braiteh, Fadi|Huang, Huiqiang|Esaki, Taito|Horibe, Keizo|Ahn, Jin-Seok|Beck, Joseph T|Edenfield, William Jeffrey|Shi, Yuankai|Taylor, Matthew|Tamura, Kenji|Van Tine, Brian A|Wu, Shang-Ju|Paolini, Jolanda
PMID: 29352732
Journal: PLoS One. 2018 Apr 11;13(4):e0194098.
Title: Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.
Author: Pritchard, Antonia L|Johansson, Peter A|Nathan, Vaishnavi|Howlie, Madeleine|Symmons, Judith|Palmer, Jane M|Hayward, Nicholas K
PMID: 29641532
Journal: J Exp Clin Cancer Res. 2018 Apr 17;37(1):84.
Title: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.
Author: Mendes Oliveira, Duarte|Grillone, Katia|Mignogna, Chiara|De Falco, Valentina|Laudanna, Carmelo|Biamonte, Flavia|Locane, Rosa|Corcione, Francesco|Fabozzi, Massimiliano|Sacco, Rosario|Viglietto, Giuseppe|Malanga, Donatella|Rizzuto, Antonia
PMID: 29665843