Primary Site >> Pancreatic Cancer

Gene >> RICTOR

Journal: Scand J Gastroenterol. 1983 Sep;18(6):791-5.
Title: Assessment of a rapid pancreatic isoamylase assay as a screening test for chronic pancreatic disease.
Author: Kelleher, J|Losowsky, M S|Ruddell, W S|Mitchell, C J|McMahon, M J|Hamilton, I
PMID: 6669943
Journal: Biochim Biophys Acta. 2010 Apr;1803(4):435-42.
Title: Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells.
Author: Lang, Sven A|Hackl, Christina|Moser, Christian|Fichtner-Feigl, Stefan|Koehl, Gudrun E|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 20116405
Journal: Mol Cancer Ther. 2015 Apr;14(4):1014-23.
Title: Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
Author: Soares, Heloisa P|Ming, Ming|Mellon, Michelle|Young, Steven H|Han, Liang|Sinnet-Smith, James|Rozengurt, Enrique
PMID: 25673820
Journal: Cancer Res. 2016 Dec 1;76(23):6911-6923.
Title: mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer.
Author: Driscoll, David R|Karim, Saadia A|Sano, Makoto|Gay, David M|Jacob, Wright|Yu, Jun|Mizukami, Yusuke|Gopinathan, Aarthi|Jodrell, Duncan I|Evans, T R Jeffry|Bardeesy, Nabeel|Hall, Michael N|Quattrochi, Brian J|Klimstra, David S|Barry, Simon T|Sansom, Owen J|
PMID: 27758884
Journal: Oncotarget. 2017 Apr 11;8(15):24491-24505.
Title: Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.
Author: Schmidt, Katharina M|Hellerbrand, Claus|Ruemmele, Petra|Michalski, Christoph W|Kong, Bo|Kroemer, Alexander|Hackl, Christina|Schlitt, Hans J|Geissler, Edward K|Lang, Sven A
PMID: 28445935