Primary Site >> Pancreatic Cancer

Gene >> RET

Journal: Curr Opin Gen Surg. 1994:60-8.
Title: Genetic aspects of multiple endocrine neoplasia types 1 and 2.
Author: Sandelin, K|Larsson, C|Decker, R A
PMID: 7584011
Journal: Am J Surg. 1997 Jan;173(1):37-41; discussion 42-3.
Title: Advances in molecular genetics.
Author: Lairmore, T C|Norton, J A
PMID: 9046882
Journal: Int J Cancer. 1999 Mar 31;81(1):67-73.
Title: Experimental implication of celiac ganglionotropic invasion of pancreatic-cancer cells bearing c-ret proto-oncogene with reference to glial-cell-line-derived neurotrophic factor (GDNF).
Author: Okada, Y|Takeyama, H|Sato, M|Morikawa, M|Sobue, K|Asai, K|Tada, T|Kato, T|Manabe, T
PMID: 10077155
Journal: J Clin Endocrinol Metab. 2001 Dec;86(12):5658-71.
Title: Guidelines for diagnosis and therapy of MEN type 1 and type 2.
Author: Brandi, M L|Gagel, R F|Angeli, A|Bilezikian, J P|Beck-Peccoz, P|Bordi, C|Conte-Devolx, B|Falchetti, A|Gheri, R G|Libroia, A|Lips, C J|Lombardi, G|Mannelli, M|Pacini, F|Ponder, B A|Raue, F|Skogseid, B|Tamburrano, G|Thakker, R V|Thompson, N W|Tomassetti, P|
PMID: 11739416
Journal: Cancer Res. 2004 Aug 1;64(15):5291-300.
Title: Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells.
Author: Veit, Christine|Genze, Felicitas|Menke, Andre|Hoeffert, Silke|Gress, Thomas M|Gierschik, Peter|Giehl, Klaudia
PMID: 15289335
Journal: Surgery. 2005 Oct;138(4):788-94.
Title: Expression of glial cell line-derived neurotrophic factor family members and their receptors in pancreatic cancers.
Author: Ito, Yoshinori|Okada, Yuji|Sato, Mikinori|Sawai, Hirozumi|Funahashi, Hitoshi|Murase, Takayuki|Hayakawa, Tetsushi|Manabe, Tadao
PMID: 16269310
Journal: Cancer Res. 2005 Dec 15;65(24):11536-44.
Title: The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.
Author: Sawai, Hirozumi|Okada, Yuji|Kazanjian, Kevork|Kim, Joseph|Hasan, Sascha|Hines, Oscar J|Reber, Howard A|Hoon, Dave S B|Eibl, Guido
PMID: 16357163
Journal: Ann Surg. 2006 Aug;244(2):274-81.
Title: The neurotrophic factor artemin promotes pancreatic cancer invasion.
Author: Ceyhan, Guralp O|Giese, Nathalia A|Erkan, Mert|Kerscher, Annika G|Wente, Moritz N|Giese, Thomas|Buchler, Markus W|Friess, Helmut
PMID: 16858191
Journal: Nephrol Ther. 2006 Jan;2 Suppl 2:S127-36.
Title: [Pathogenic patterns of genetic predisposition to endocrine tumors].
Author: Calender, Alain
PMID: 17373213
Journal: Eur J Endocrinol. 2008 Mar;158(3):417-22.
Title: Uncommon association of germline mutations of RET proto-oncogene and CDKN2A gene.
Author: Foppiani, L|Forzano, F|Ceccherini, I|Bruno, W|Ghiorzo, P|Caroli, F|Quilici, P|Bandelloni, R|Arlandini, A|Sartini, G|Cabria, M|Del Monte, P
PMID: 18299477
Journal: J Int Med Res. 2008 Jul-Aug;36(4):656-64.
Title: The relationship between overexpression of glial cell-derived neurotrophic factor and its RET receptor with progression and prognosis of human pancreatic cancer.
Author: Zeng, Q|Cheng, Y|Zhu, Q|Yu, Z|Wu, X|Huang, K|Zhou, M|Han, S|Zhang, Q
PMID: 18652760
Journal: J Clin Endocrinol Metab. 2009 Feb;94(2):386-91.
Title: Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors.
Author: Jimenez, Camilo|Cabanillas, Maria E|Santarpia, Libero|Jonasch, Eric|Kyle, Karen L|Lano, Elizabeth A|Matin, Surena F|Nunez, Rodolfo F|Perrier, Nancy D|Phan, Alexandria|Rich, Thereasa A|Shah, Beejal|Williams, Michelle D|Waguespack, Steven G
PMID: 19017755
Journal: World J Surg. 2009 Apr;33(4):710-5.
Title: CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer.
Author: Donahue, Timothy R|Hines, O Joe
PMID: 19057948
Journal: Clin Cancer Res. 2009 Nov 15;15(22):7061-8.
Title: Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies.
Author: Hong, David S|Sebti, Said M|Newman, Robert A|Blaskovich, Michelle A|Ye, Lei|Gagel, Robert F|Moulder, Stacy|Wheler, Jennifer J|Naing, Aung|Tannir, Nizar M|Ng, Chaan S|Sherman, Steven I|El Naggar, Adel K|Khan, Rabia|Trent, Jon|Wright, John J|Kurzrock, Razel
PMID: 19903778
Journal: J Natl Cancer Inst. 2010 Jan 20;102(2):107-18.
Title: Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.
Author: Gil, Ziv|Cavel, Oren|Kelly, Kaitlyn|Brader, Peter|Rein, Avigail|Gao, Sizhi P|Carlson, Diane L|Shah, Jatin P|Fong, Yuman|Wong, Richard J
PMID: 20068194
Journal: Int J Colorectal Dis. 2011 Jul;26(7):835-40.
Title: RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.
Author: Ruckert, Felix|Gorgens, Heike|Richter, Ines|Krex, Dietmar|Schackert, Gabriele|Kuhlisch, Eberhard|Fitze, Guido|Saeger, Hans-Detlev|Pilarsky, Christian|Grutzmann, Robert|Schackert, Hans K
PMID: 21311890
Journal: Eur J Endocrinol. 2011 Mar;164(3):397-404.
Title: CDKN1B V109G polymorphism a new prognostic factor in sporadic medullary thyroid carcinoma.
Author: Pasquali, Daniela|Circelli, Luisa|Faggiano, Antongiulio|Pancione, Massimo|Renzullo, Andrea|Elisei, Rossella|Romei, Cristina|Accardo, Giacomo|Coppola, Viviana Raffaella|De Palma, Maurizio|Ferolla, Piero|Grimaldi, Franco|Colao, Annamaria|Colantuoni, Vittori
PMID: 21177330
Journal: Mol Cell Biochem. 2011 Jan;347(1-2):95-101.
Title: High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cells.
Author: Liu, Han|Ma, Qingyong|Li, Junhui
PMID: 20960036
Journal: Melanoma Res. 2012 Feb;22(1):92-5.
Title: The RET G691S polymorphism is a germline variant in desmoplastic malignant melanoma.
Author: Barr, Jodie|Amato, Carol M|Robinson, Steven E|Kounalakis, Nicole|Robinson, William A
PMID: 22189301
Journal: Cancer Res. 2012 Nov 15;72(22):5733-43.
Title: Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor.
Author: Cavel, Oren|Shomron, Olga|Shabtay, Ayelet|Vital, Joseph|Trejo-Leider, Leonor|Weizman, Noam|Krelin, Yakov|Fong, Yuman|Wong, Richard J|Amit, Moran|Gil, Ziv
PMID: 22971345
Journal: Curr Pharm Des. 2013;19(5):864-82.
Title: Inhibition of RET activated pathways: novel strategies for therapeutic intervention in human cancers.
Author: Santarpia, Libero|Bottai, Giulia
PMID: 22973956
Journal: Hered Cancer Clin Pract. 2013 Apr 1;11(1):2.
Title: Systemic treatment for hereditary cancers: a 2012 update.
Author: Imyanitov, Evgeny N|Byrski, Tomasz
PMID: 23548133
Journal: Endocrinol Diabetes Metab Case Rep. 2013;2013:130021.
Title: Medullary thyroid carcinoma and duodenal calcitonin-secreting neuroendocrine tumour: more than coincidence?
Author: Huguet, I|Lamas, C|Vera, R|Lomas, A|Quilez, R P|Grossman, A|Botella, F
PMID: 24616764
Journal: Vasc Cell. 2014 Sep 6;6:18.
Title: Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage.
Author: Yamamoto, Yuji|Matsui, Junji|Matsushima, Tomohiro|Obaishi, Hiroshi|Miyazaki, Kazuki|Nakamura, Katsuji|Tohyama, Osamu|Semba, Taro|Yamaguchi, Atsumi|Hoshi, Sachi Suzuki|Mimura, Fusayo|Haneda, Toru|Fukuda, Yoshio|Kamata, Jun-Ichi|Takahashi, Keiko|Matsukura,
PMID: 25197551
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):392-403.
Title: The molecular mechanisms of a novel multi-kinase inhibitor ZLJ33 in suppressing pancreatic cancer growth.
Author: Li, Yan|Tang, Ke|Zhang, Lijing|Li, Chao|Niu, Fei|Zhou, Wanqi|Yang, Hanze|Feng, Zhiqiang|Chen, Xiaoguang
PMID: 25301453
Journal: Virchows Arch. 2015 Feb;466(2):237-41.
Title: Basaloid carcinoma of the pancreas--clinicopathological presentation and oncogenetic snapshot of a rare entity.
Author: Szasz, A Marcell|Szirtes, Ildiko|Tihanyi, Balazs|Barkaszi, Bernadett|Baranyai, Zsolt|Tihanyi, Tibor|Harsanyi, Laszlo|Timar, Jozsef|Kulka, Janina
PMID: 25432630
Journal: Int J Biol Markers. 2015 May 26;30(2):e226-33.
Title: Identification of biomarkers for the prognosis of pancreatic ductal adenocarcinoma with miRNA microarray data.
Author: Wang, Song|Zhao, Yanxun|Li, Dongsheng|Zhu, Liangchen|Shen, Zugang
PMID: 25791160
Journal: Invest New Drugs. 2016 Apr;34(2):176-83.
Title: Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers.
Author: Kessler, Elizabeth R|Eckhardt, S Gail|Pitts, Todd M|Bradshaw-Pierce, Erica L|O'byrant, Cindy L|Messersmith, Wells A|Nallapreddy, Sujatha|Weekes, Colin|Spratlin, Jennifer|Lieu, Christopher H|Kane, Madeleine A|Eppers, Sarah|Freas, Elizabeth|Leong, Stephen
PMID: 26715573
Journal: Eur J Med Chem. 2016 Apr 13;112:20-32.
Title: The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
Author: Newton, Rebecca|Bowler, Katherine A|Burns, Emily M|Chapman, Philip J|Fairweather, Emma E|Fritzl, Samantha J R|Goldberg, Kristin M|Hamilton, Niall M|Holt, Sarah V|Hopkins, Gemma V|Jones, Stuart D|Jordan, Allan M|Lyons, Amanda J|Nikki March, H|McDonald, Nei
PMID: 26874741
Journal: Anticancer Res. 2016 Oct;36(10):5025-5030.
Title: Antiangiogenic Therapy in Pancreatic Neuroendocrine Tumors.
Author: Capozzi, Monica|VON Arx, Claudia|DE Divitiis, Chiara|Ottaiano, Alessandro|Tatangelo, Fabiana|Romano, Giovanni Maria|Tafuto, Salvatore
PMID: 27798861
Journal: Oncogene. 2017 Jun 8;36(23):3232-3239.
Title: Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma.
Author: Amit, M|Na'ara, S|Leider-Trejo, L|Binenbaum, Y|Kulish, N|Fridman, E|Shabtai-Orbach, A|Wong, R J|Gil, Z
PMID: 28092668
Journal: Lancet Oncol. 2017 Apr;18(4):486-499.
Title: Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial.
Author: Middleton, Gary|Palmer, Daniel H|Greenhalf, William|Ghaneh, Paula|Jackson, Richard|Cox, Trevor|Evans, Anthony|Shaw, Victoria E|Wadsley, Jonathan|Valle, Juan W|Propper, David|Wasan, Harpreet|Falk, Stephen|Cunningham, David|Coxon, Fareeda|Ross, Paul|Madhusu
PMID: 28259610
Journal: Dtsch Med Wochenschr. 2017 Sep;142(18):1379-1389.
Title: [Multiple endocrine neoplasia].
Author: Schaaf, Ludwig|Raue, Friedhelm
PMID: 28902384