Primary Site >> Stomach Cancer

Gene >> RASSF1

Journal: Cancer Res. 2001 Oct 1;61(19):7034-8.
Title: Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma.
Author: Byun, D S|Lee, M G|Chae, K S|Ryu, B G|Chi, S G
PMID: 11585730
Journal: Am J Pathol. 2002 Mar;160(3):787-94.
Title: Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Woo Ho|Lee, Hye Won|Kim, Jin Cheon|Rhyu, Mun-Gan|Ro, Jae Y
PMID: 11891177
Journal: Int J Cancer. 2002 Dec 20;102(6):623-8.
Title: Promoter hypermethylation of tumor-related genes in gastric intestinal metaplasia of patients with and without gastric cancer.
Author: To, Ka-Fai|Leung, Wai K|Lee, Tin-Lap|Yu, Jun|Tong, Joanna H M|Chan, Michael W Y|Ng, Enders K W|Chung, S C Sydney|Sung, Joseph J Y
PMID: 12448005
Journal: Histol Histopathol. 2003 Apr;18(2):665-77.
Title: Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis.
Author: Dammann, R|Schagdarsurengin, U|Strunnikova, M|Rastetter, M|Seidel, C|Liu, L|Tommasi, S|Pfeifer, G P
PMID: 12647816
Journal: J Pathol. 2003 May;200(1):23-31.
Title: Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability.
Author: Kim, Hyunki|Kim, Yun Hee|Kim, Sung Eun|Kim, Nam-Gyun|Noh, Sung Hoon|Kim, Hoguen
PMID: 12692837
Journal: Lab Invest. 2003 Apr;83(4):519-26.
Title: Profile of aberrant CpG island methylation along multistep gastric carcinogenesis.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Jung-Sun|Jung, Hwoon-Yong
PMID: 12695555
Journal: Lab Invest. 2003 May;83(5):635-41.
Title: Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogenesis.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Jung-Sun|Jung, Hwoon-Yong
PMID: 12746473
Journal: Am J Pathol. 2003 Oct;163(4):1551-6.
Title: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation.
Author: Kang, Gyeong Hoon|Lee, Hyeon Joo|Hwang, Kyu Sang|Lee, Sun|Kim, Jae-Hoon|Kim, Jung-Sun
PMID: 14507661
Journal: Histol Histopathol. 2004 Jan;19(1):221-8.
Title: Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia.
Author: Tamura, G
PMID: 14702190
Journal: J Korean Med Sci. 2005 Oct;20(5):790-805.
Title: Relationship between the extent of chromosomal losses and the pattern of CpG methylation in gastric carcinomas.
Author: Hong, Seung-Jin|Kim, Young-Ho|Choi, Young-Deok|Min, Ki-Ouk|Choi, Sang-Wook|Rhyu, Mun-Gan
PMID: 16224153
Journal: Br J Cancer. 2005 Dec 12;93(12):1395-9.
Title: RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer.
Author: Endoh, M|Tamura, G|Honda, T|Homma, N|Terashima, M|Nishizuka, S|Motoyama, T
PMID: 16265349
Journal: Oncogene. 2005 Nov 17;24(51):7630-4.
Title: Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
Author: Oliveira, Carla|Velho, Sergia|Domingo, Enric|Preto, Ana|Hofstra, Robert M W|Hamelin, Richard|Yamamoto, Hiroyuki|Seruca, Raquel|Schwartz, Simo Jr
PMID: 16007118
Journal: Histol Histopathol. 2005 Apr;20(2):645-63.
Title: The tumor suppressor RASSF1A in human carcinogenesis: an update.
Author: Dammann, R|Schagdarsurengin, U|Seidel, C|Strunnikova, M|Rastetter, M|Baier, K|Pfeifer, G P
PMID: 15736067
Journal: World J Gastroenterol. 2006 Jan 14;12(2):192-8.
Title: Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer.
Author: Tamura, Gen
PMID: 16482617
Journal: Cancer Sci. 2006 Sep;97(9):938-44. Epub 2006 Jun 29.
Title: Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.
Author: Zhang, Xiaotian|Yashiro, Masakazu|Ohira, Masaichi|Ren, Jun|Hirakawa, Kosei
PMID: 16805821
Journal: Zhonghua Nei Ke Za Zhi. 2006 Dec;45(12):1008-12.
Title: [The influence of promoter methylation of RASSF1A on RASSF1A mRNA and protein expression in gastric cancer tissues].
Author: Ye, Mei|Xia, Bing|Guo, Qiu-sha|Zhou, Feng|Zhang, Xiao-lian
PMID: 17327001
Journal: Hum Pathol. 2007 Jun;38(6):903-13. Epub 2007 Mar 21.
Title: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Author: Milne, Anya N A|Sitarz, Robert|Carvalho, Ralph|Polak, Mirjam M|Ligtenberg, Marjolijn|Pauwels, Patrick|Offerhaus, G Johan A|Weterman, Marian A J
PMID: 17376510
Journal: BMC Cancer. 2007 Jul 3;7:120.
Title: Association of diminished expression of RASSF1A with promoter methylation in primary gastric cancer from patients of central China.
Author: Ye, Mei|Xia, Bing|Guo, Qiusha|Zhou, Feng|Zhang, Xiaolian
PMID: 17608924
Journal: World J Gastroenterol. 2008 Jan 28;14(4):595-600.
Title: Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB.
Author: Shen, Wen-Jing|Dai, Dong-Qiu|Teng, Yue|Liu, Hong-Bo
PMID: 18203293
Journal: World J Gastroenterol. 2008 Mar 7;14(9):1437-43.
Title: Activator protein-1 involved in growth inhibition by RASSF1A gene in the human gastric carcinoma cell line SGC7901.
Author: Deng, Zheng-Hao|Wen, Ji-Fang|Li, Jing-He|Xiao, De-Sheng|Zhou, Jian-Hua
PMID: 18322962
Journal: Hum Pathol. 2009 Nov;40(11):1534-42.
Title: Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions.
Author: Zou, Xiao-Ping|Zhang, Bin|Zhang, Xiao-Qi|Chen, Min|Cao, Jun|Liu, Wen-Jia
PMID: 19695681
Journal: Cancer Sci. 2009 Jan;100(1):181-8.
Title: DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells.
Author: Qiu, Hong|Yashiro, Masakazu|Shinto, Osamu|Matsuzaki, Taro|Hirakawa, Kosei
PMID: 19037991
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Jan;12(1):57-60.
Title: [5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells].
Author: Shen, Wen-Jing|Dai, Dong-Qiu|Teng, Yue|Liu, Hong-Bo
PMID: 19145506
Journal: J Surg Oncol. 2011 Jun 1;103(7):687-94.
Title: Hypermethylation of tumor-related genes in Tunisian patients with gastric carcinoma: clinical and biological significance.
Author: Ben Ayed-Guerfali, Dorra|Benhaj, Khemais|Khabir, Abdelmajid|Abid, Mohamed|Bayrouti, Mohamed Issam|Sellami-Boudawara, Tahia|Gargouri, Ali|Mokdad-Gargouri, Raja
PMID: 21308683
Journal: Cancer Lett. 2011 Dec 1;311(1):85-95.
Title: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).
Author: Balassiano, Karen|Lima, Sheila|Jenab, Mazda|Overvad, Kim|Tjonneland, Anne|Boutron-Ruault, Marie Christine|Clavel-Chapelon, Francoise|Canzian, Federico|Kaaks, Rudolf|Boeing, Heiner|Meidtner, Karina|Trichopoulou, Antonia|Laglou, Pagona|Vineis, Paolo|Panico,
PMID: 21831520
Journal: Clin Chim Acta. 2012 Apr 11;413(7-8):787-94.
Title: Quantitative assessment of gene methylation and their impact on clinical outcome in gastric cancer.
Author: Yao, Demao|Shi, Jing|Shi, Bingyin|Wang, Na|Liu, Wei|Zhang, Guanjun|Ji, Meiju|Xu, Li|He, Nongyue|Hou, Peng
PMID: 22285775
Journal: APMIS. 2012 Jul;120(7):582-90.
Title: Galectin-1 is up-regulated by RASSF1A gene in human gastric carcinoma cell line SGC7901.
Author: Zheng-Hao, Deng|Ji-Fang, Wen|De-Sheng, Xiao|Jian-Hua, Zhou
PMID: 22716213
Journal: Histol Histopathol. 2012 Oct;27(10):1271-82.
Title: Promoter methylation of tumor-related genes in gastric carcinogenesis.
Author: Zhao, Chenghai|Bu, Xianmin
PMID: 22936446
Journal: Oncol Rep. 2013 Nov;30(5):2419-26.
Title: 3,3'-Diindolylmethane suppresses the growth of gastric cancer cells via activation of the Hippo signaling pathway.
Author: Li, Xiu Juan|Park, Eun Sung|Park, Man Hee|Kim, Soo Mi
PMID: 24008339
Journal: Clin Biochem. 2013 Oct 25. pii: S0009-9120(13)00488-8.
Title: Concomitant PIK3CA amplification and RASSF1A or PAX6 hypermethylation predict worse survival in gastric cancer.
Author: Yang, Qi|Shao, Yuan|Shi, Jing|Qu, Yiping|Wu, Kexia|Dang, Siwen|Shi, Bingyin|Hou, Peng
PMID: 24513424
Journal: Klin Lab Diagn. 2013 Nov;(11):12-5.
Title: [The systems of molecular genetic markers under cancer of stomach].
Author: Nemtsova, M V|Bykov, I I|Tchekinova, N V|Zaletaev, D V|Glikhov, A I|Khorobrykh, T V
PMID: 24640104
Journal: Zhonghua Yi Xue Za Zhi. 2014 Jul 22;94(28):2193-6.
Title: [Promoter region methylation of DNA damage repair genes in human gastric cancer].
Author: Guo, He|Yan, Wenji|Yang, Yunsheng|Guo, Mingzhou
PMID: 25331470
Journal: Clin Biochem. 2014 Jan;47(1-2):111-6.
Title: Concomitant PIK3CA amplification and RASSF1A or PAX6 hypermethylation predict worse survival in gastric cancer.
Author: Yang, Qi|Shao, Yuan|Shi, Jing|Qu, Yiping|Wu, Kexia|Dang, Siwen|Shi, Bingyin|Hou, Peng
PMID: 24505629
Journal: Tumour Biol. 2014 Feb;35(2):943-8.
Title: Association of RASSF1A promoter methylation with gastric cancer risk: a meta-analysis.
Author: Shi, Dong-Tao|Han, Mei|Gao, Nan|Tian, Wenyan|Chen, Weichang
PMID: 23982879
Journal: Gastric Cancer. 2015 Apr;18(2):280-7.
Title: Predictive value of CHFR and MLH1 methylation in human gastric cancer.
Author: Li, Yazhuo|Yang, Yunsheng|Lu, Youyong|Herman, James G|Brock, Malcolm V|Zhao, Po|Guo, Mingzhou
PMID: 24748501
Journal: Mol Med Rep. 2015 Apr;11(4):3039-46.
Title: CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis.
Author: Joo, Moon Kyung|Kim, Key Hyeon|Park, Jong-Jae|Yoo, Hyo Soon|Choe, Jungwan|Kim, Hyo Jung|Lee, Beom Jae|Kim, Jae Seon|Bak, Young-Tae
PMID: 25483734
Journal: Gene Ther. 2015 Oct;22(10):793-801.
Title: Lentivirus-mediated RASSF1A expression suppresses aggressive phenotypes of gastric cancer cells in vitro and in vivo.
Author: Zhou, P-H|Zheng, J-B|Wei, G-B|Wang, X-L|Wang, W|Chen, N-Z|Yu, J-H|Yao, J-F|Wang, H|Lu, S-Y|Sun, X-J
PMID: 26005859
Journal: Mutat Res. 2015 Aug;778:46-51.
Title: Prognostic role of APC and RASSF1A promoter methylation status in cell free circulating DNA of operable gastric cancer patients.
Author: Balgkouranidou, I|Matthaios, D|Karayiannakis, A|Bolanaki, H|Michailidis, P|Xenidis, N|Amarantidis, K|Chelis, L|Trypsianis, G|Chatzaki, E|Lianidou, E S|Kakolyris, S
PMID: 26073472
Journal: Oncotarget. 2016 Feb 2;7(5):5842-51.
Title: RASSF1A inhibits gastric cancer cell proliferation by miR-711- mediated downregulation of CDK4 expression.
Author: Liao, Aijun|Tan, Gao|Chen, Lin|Zhou, Weiwei|Hu, Hongsai
PMID: 26735582
Journal: PeerJ. 2016 Jun 9;4:e2112.
Title: Aberrant methylation of PCDH10 and RASSF1A genes in blood samples for non-invasive diagnosis and prognostic assessment of gastric cancer.
Author: Pimson, Charinya|Ekalaksananan, Tipaya|Pientong, Chamsai|Promthet, Supannee|Putthanachote, Nuntiput|Suwanrungruang, Krittika|Wiangnon, Surapon
PMID: 27330867
Journal: J Gastrointest Oncol. 2016 Dec;7(6):989-995.
Title: Diminished expression of MGMT & RASSF1A genes in gastric cancer in ethnic population of Kashmir.
Author: Bhat, Arif Akbar|Wani, Hilal Ahmad|Waza, Ajaz Ahmad|Malik, Rawoof Ahmad|Masood, Akbar|Jeelani, Showkat|Kadla, Showkat|Majid, Sabhiya
PMID: 28078123
Journal: Front Med (Lausanne). 2017 May 2;4:47.
Title: Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection.
Author: Rivas-Ortiz, Claudia I|Lopez-Vidal, Yolanda|Arredondo-Hernandez, Luis Jose Rene|Castillo-Rojas, Gonzalo
PMID: 28512631
Journal: Curr Genomics. 2017 Oct;18(5):408-415.
Title: Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice.
Author: Nemtsova, Marina V|Strelnikov, Vladimir V|Tanas, Alexander S|Bykov, Igor I|Zaletaev, Dmitry V|Rudenko, Viktoria V|Glukhov, Alexander I|Kchorobrich, Tatiana V|Li, Yi|Tarasov, Vadim V|Barreto, George E|Aliev, Gjumrakch
PMID: 29081696
Journal: Oncotarget. 2017 Sep 8;8(44):77783-77793.
Title: Promoter methylation of tumor-related genes as a potential biomarker using blood samples for gastric cancer detection.
Author: Wen, Jinfeng|Zheng, Tuo|Hu, Kefeng|Zhu, Chunxia|Guo, Lihua|Ye, Guoliang
PMID: 29100425
Journal: Oncol Rep. 2018 Oct;40(4):1959-1970.
Title: MicroRNA181a promotes cell proliferation and inhibits apoptosis in gastric cancer by targeting RASSF1A.
Author: Yu, Junhui|Qi, Jie|Sun, Xuejun|Wang, Wei|Wei, Guangbing|Wu, Yunhua|Gao, Qi|Zheng, Jianbao
PMID: 30106448