Primary Site >> Esophagus Cancer

Gene >> PTEN

Journal: Int J Oncol. 2000 Oct;17(4):695-9.
Title: PTEN/MMAC1 expression in esophageal squamous cell carcinomas.
Author: Ding, Y|Shimada, Y|Kano, M|Itami, A|Kawabe, A|Maeda, M|Li, Z|Hong, T|Sato, F|Kaganoi, J|Imamura, M
PMID: 10995879
Journal: Cancer. 2002 Apr 1;94(7):1955-60.
Title: Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma.
Author: Tachibana, Mitsuo|Shibakita, Muneaki|Ohno, Satoshi|Kinugasa, Shoichi|Yoshimura, Hiroshi|Ueda, Shuhei|Fujii, Toshiyuki|Rahman, Mohammad A|Dhar, Dipok K|Nagasue, Naofumi
PMID: 11932897
Journal: Dis Esophagus. 2006;19(6):454-8.
Title: Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma.
Author: Ando, T|Ishiguro, H|Kimura, M|Mitsui, A|Kurehara, H|Sugito, N|Tomoda, K|Mori, R|Takashima, N|Ogawa, R|Fujii, Y|Kuwabara, Y
PMID: 17069588
Journal: Dis Esophagus. 2007;20(6):491-6.
Title: Prognostic significance of PTEN expression in esophageal squamous cell carcinoma from Linzhou City, a high incidence area of northern China.
Author: Chang, D|Wang, T-Y|Li, H-C|Wei, J-C|Song, J-X
PMID: 17958724
Journal: Dis Esophagus. 2008;21(5):409-15.
Title: PTEN polymorphisms and the risk of esophageal carcinoma and gastric cardiac carcinoma in a high incidence region of China.
Author: Ge, H|Cao, Y Y|Chen, L Q|Wang, Y M|Chen, Z F|Wen, D G|Zhang, X F|Guo, W|Wang, N|Li, Y|Zhang, J H
PMID: 19125794
Journal: J Clin Oncol. 2009 Feb 20;27(6):857-71.
Title: Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.
Author: Hildebrandt, Michelle A T|Yang, Hushan|Hung, Mien-Chie|Izzo, Julie G|Huang, Maosheng|Lin, Jie|Ajani, Jaffer A|Wu, Xifeng
PMID: 19164214
Journal: Int J Oncol. 2010 Jan;36(1):19-27.
Title: A novel pharmacodynamic approach to assess and predict tumor response to the epidermal growth factor receptor inhibitor gefitinib in patients with esophageal cancer.
Author: Altiok, Soner|Mezzadra, Heather|Jagannath, Sanjay|Tsottles, Nancy|Rudek, Michelle A|Abdallah, Nadia|Berman, David|Forastiere, Arlene|Gibson, Michael K
PMID: 19956829
Journal: Biosci Biotechnol Biochem. 2010;74(4):736-40. Epub 2010 Apr 7.
Title: The adenovirus-mediated transfer of PTEN inhibits the growth of esophageal cancer cells in vitro and in vivo.
Author: Zhou, Yong-An|Zhang, Tao|Zhao, Jin-Bo|Wang, Xiao-Ping|Jiang, Tao|Gu, Zhong-Ping|Wang, Xian-Ni|Li, Xiao-Fei
PMID: 20378992
Journal: Wei Sheng Yan Jiu. 2010 Jul;39(4):444-6.
Title: [Apoptosis effects on human esophageal cancer cells by soyasaponin Bb and its machanism].
Author: Pei, Yingxin|Zhao, Huanhuan|Du, Xiaoyan|Li, Jinping
PMID: 20726234
Journal: Mol Biol Rep. 2011 Jun;38(5):3253-60.
Title: Role of microRNA-21 and effect on PTEN in Kazakh's esophageal squamous cell carcinoma.
Author: Ma, Wen-Jing|Lv, Guo-Dong|Tuersun, Aerziguli|Liu, Qing|Liu, Hui|Zheng, Shu-Tao|Huang, Cong-Gai|Feng, Jun-Guo|Wang, Xing|Lin, Ren-Yong|Sheyhidin, Ilyar|Lu, Xiao-Mei
PMID: 21104017
Journal: Cancer Biol Ther. 2011 Jun 1;11(11):950-8. Epub 2011 Jun 1.
Title: The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells.
Author: Li, Hongxia|Gao, Quanli|Guo, Liping|Lu, Shih Hsin
PMID: 21467840
Journal: World J Gastroenterol. 2012 Aug 21;18(31):4127-35.
Title: siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin.
Author: Hasan, Raghibul|Chauhan, Shyam Singh|Sharma, Rinu|Ralhan, Ranju
PMID: 22919244
Journal: Dis Esophagus. 2013 Nov-Dec;26(8):823-31.
Title: Inhibition of microRNA-21 increases radiosensitivity of esophageal cancer cells through phosphatase and tensin homolog deleted on chromosome 10 activation.
Author: Huang, S|Li, X-Q|Chen, Xin|Che, S-M|Chen, W|Zhang, X-Z
PMID: 22958183
Journal: Oncol Rep. 2013 Jan;29(1):45-50.
Title: Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.
Author: Bao, Xiao-Hong|Takaoka, Munenori|Hao, Hui-Fang|Fukazawa, Takuya|Yamatsuji, Tomoki|Sakurama, Kazufumi|Takigawa, Nagio|Nakajima, Motowo|Fujiwara, Toshiyoshi|Naomoto, Yoshio
PMID: 23064324
Journal: Dig Dis Sci. 2013 Dec;58(12):3483-93.
Title: Down-regulation of PTEN expression modulated by dysregulated miR-21 contributes to the progression of esophageal cancer.
Author: Li, Pei|Mao, Wei-Min|Zheng, Zhi-Guo|Dong, Zi-Ming|Ling, Zhi-Qiang
PMID: 24221338
Journal: Anticancer Res. 2013 Dec;33(12):5407-14.
Title: A novel chemotherapeutic arene ruthenium(II) drug Rawq01 altered the effect of microRNA-21 on PTEN/AKT signaling pathway in esophageal cancer cells.
Author: Weng, Wenhao|Wu, Qiong|Yu, Yongchun|Mei, Wenjie|Wang, Xinghe
PMID: 24324076
Journal: Chin Med J (Engl). 2014;127(2):353-8.
Title: Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy.
Author: Yang, Yang|Wen, Fengbiao|Dang, Lifeng|Fan, Yuxia|Liu, Donglei|Wu, Kai|Zhao, Song
PMID: 24438628
Journal: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Sep;31(5):465-8.
Title: [The effects of curcumin on PTEN/PI3K/Akt pathway in Ec109 cells].
Author: Li, Xiu-juan|Luo, Qiang|Sun, Li|Lit, Hua|Jin, Chun-ting|Fan, Jie|Li, Yu-zhen
PMID: 26827544
Journal: Int J Oncol. 2015 Dec;47(6):2255-63.
Title: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells.
Author: Hadisaputri, Yuni Elsa|Miyazaki, Tatsuya|Suzuki, Shigemasa|Kubo, Norio|Zuhrotun, Ade|Yokobori, Takehiko|Abdulah, Rizky|Yazawa, Shin|Kuwano, Hiroyuki
PMID: 26498695
Journal: Tumour Biol. 2015 Aug;36(8):5849-57.
Title: PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma.
Author: Sun, Zhenguo|Ji, Na|Bi, Mingming|Wang, Shuai|Liu, Xiangyan|Wang, Zhou
PMID: 25724185
Journal: Genet Mol Res. 2015 Aug 3;14(3):8810-8.
Title: Characterization and effects of miR-21 expression in esophageal cancer.
Author: Wen, S-W|Zhang, Y-F|Li, Y|Liu, Z-X|Lv, H-L|Li, Z-H|Xu, Y-Z|Zhu, Y-G|Tian, Z-Q
PMID: 26345812
Journal: Oncologist. 2015 Oct;20(10):1132-9.
Title: Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences.
Author: Wang, Kai|Johnson, Adrienne|Ali, Siraj M|Klempner, Samuel J|Bekaii-Saab, Tanios|Vacirca, Jeffrey L|Khaira, Depinder|Yelensky, Roman|Chmielecki, Juliann|Elvin, Julia A|Lipson, Doron|Miller, Vincent A|Stephens, Philip J|Ross, Jeffrey S
PMID: 26336083
Journal: PLoS One. 2015 Jul 14;10(7):e0133097.
Title: Correction: Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation.
Author: He, Enhui|Pan, Fei|Li, Guangchao|Li, Jingjing
PMID: 26173079
Journal: PLoS One. 2015 May 22;10(5):e0126149.
Title: Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation.
Author: He, Enhui|Pan, Fei|Li, Guangchao|Li, Jingjing
PMID: 26000878
Journal: BMC Cancer. 2015 Jan 31;15:29.
Title: MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells.
Author: Yu, Tingting|Cao, Risheng|Li, Shuo|Fu, Mingen|Ren, Lihua|Chen, Weixu|Zhu, Hong|Zhan, Qiang|Shi, Ruihua
PMID: 25637514
Journal: Cancer Genet. 2015 Jan-Feb;208(1-2):41-6.
Title: Esophageal cancer in a family with hamartomatous tumors and germline PTEN frameshift and SMAD7 missense mutations.
Author: Sherman, Scott K|Maxwell, Jessica E|Qian, Qining|Bellizzi, Andrew M|Braun, Terry A|Iannettoni, Mark D|Darbro, Benjamin W|Howe, James R
PMID: 25554686
Journal: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Mar;31(2):174-7.
Title: [Curcumin induces apoptosis by PTEN/PI3K/AKT pathway in EC109 cells].
Author: Li, Xiu-juan|Li, Yu-zhen|Jin, Chun-ting|Fan, Jie|Li, Hai-jun
PMID: 26248429
Journal: Tumour Biol. 2016 Sep;37(9):12061-12070. Epub 2016 May 17.
Title: MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer.
Author: Wu, Yan-Ran|Qi, Hai-Jun|Deng, Dan-Fang|Luo, Ying-Ying|Yang, Sheng-Lan
PMID: 27188433
Journal: Mol Cell Biochem. 2016 Nov;422(1-2):161-170. Epub 2016 Sep 19.
Title: Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN.
Author: Jin, Ying-Ying|Chen, Qing-Juan|Xu, Kun|Ren, Hong-Tao|Bao, Xing|Ma, Yi-Nan|Wei, Yang|Ma, Hong Bing
PMID: 27644195
Journal: PLoS One. 2016 Oct 4;11(10):e0164105.
Title: MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression.
Author: Wang, Bin|Yang, Jie|Xiao, Bin
PMID: 27701465
Journal: Mol Cell Biochem. 2017 Jul;431(1-2):75-85.
Title: Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors.
Author: Ohnami, Shumpei|Ohshima, Keiichi|Nagashima, Takeshi|Urakami, Kenichi|Shimoda, Yuji|Saito, Junko|Naruoka, Akane|Hatakeyama, Keiichi|Mochizuki, Tohru|Serizawa, Masakuni|Ohnami, Sumiko|Kusuhara, Masatoshi|Yamaguchi, Ken
PMID: 28258440
Journal: Oncol Lett. 2017 Oct;14(4):4897-4905.
Title: Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway.
Author: Qian, Li-Qiang|Li, Xia-Qin|Ye, Peng-Hui|Su, Hao-Yuan|Wang, Gang|Liu, Yan|Shen, Gen-Hai|Gao, Quan-Gen
PMID: 29085498
Journal: Oncotarget. 2017 Jun 27;8(41):69610-69621.
Title: Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing.
Author: Yuan, Wenqing|Liu, Zhen|Lei, Wanjun|Sun, Li|Yang, Haijun|Wang, Yu|Ramdas, Shweta|Dong, Xiao|Xu, Ruiping|Cai, Hong|Li, Jun Z|Ke, Yang
PMID: 29050228
Journal: Cancer Res. 2017 Sep 29. pii: canres.0938.2017.
Title: Multiregional sequencing reveals genomic alterations and clonal dynamics in primary malignant melanoma of the esophagus.
Author: Li, Jingjing|Yan, Shi|Liu, Zhen|Zhou, Yong|Pan, Yaqi|Yuan, Wenqing|Liu, Mengfei|Tan, Qin|Tian, Geng|Dong, Bin|Cai, Hong|Wu, Nan|Ke, Yang
PMID: 28972077
Journal: Exp Cell Res. 2017 Sep 27. pii: S0014-4827(17)30517-7.
Title: The long noncoding RNA CASC2 inhibits tumorigenesis through modulating the expression of PTEN by targeting miR-18a-5p in esophageal carcinoma.
Author: Zhang, Wenjing|He, Wei|Gao, Jianfeng|Wang, Yuanyuan|Zang, Wenqiao|Dong, Ziming|Zhao, Guoqiang
PMID: 28964779
Journal: Exp Cell Res. 2018 Jan 15;362(2):362-369.
Title: Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway.
Author: Jin, Yingying|Xu, Kun|Chen, Qingjuan|Wang, Baofeng|Pan, Jiyuan|Huang, Shan|Wei, Yang|Ma, Hongbing
PMID: 29208461
Journal: Biomed Environ Sci. 2018 Mar;31(3):171-185.
Title: miR-93-5p Transferred by Exosomes Promotes the Proliferation of Esophageal Cancer Cells via Intercellular Communication by Targeting PTEN.
Author: Liu, Meng Xin|Liao, Juan|Xie, Ming|Gao, Zhi Kui|Wang, Xiang Hu|Zhang, Ying|Shang, Mu He|Yin, Li Hong|Pu, Yue Pu|Liu, Ran
PMID: 29673440
Journal: Exp Cell Res. 2018 Aug 1;369(1):176.
Title: Retraction notice to "The long noncoding RNA CASC2 inhibits tumorigenesis through modulating the expression of PTEN by targeting miR-18a-5p in esophageal carcinoma" [Experimental Cell Research 361 (2017) 30-38].
Author: Zhang, Wenjing|He, Wei|Gao, Jianfeng|Wang, Yuanyuan|Zang, Wenqiao|Dong, Ziming|Zhao, Guoqiang
PMID: 29880422
Journal: Eur Rev Med Pharmacol Sci. 2018 Jul;22(14):4532-4541.
Title: MicroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1.
Author: Zang, R-K|Ma, J-B|Liang, Y-C|Wang, Y|Hu, S-L|Zhang, Y|Dong, W|Zhang, W|Hu, L-K
PMID: 30058693