Primary Site >> Colorectal Cancer

Gene >> POLR2A

Journal: Cancer Res. 1999 May 15;59(10):2302-6.
Title: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
Author: Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Danenberg, P V|Laird, P W
PMID: 10344733
Journal: Anal Biochem. 2006 Mar 1;350(1):71-80.
Title: Validation of real-time reverse-transcription-polymerase chain reaction for quantification of capecitabine-metabolizing enzymes.
Author: Macpherson, Janet S|Jodrell, Duncan I|Guichard, Sylvie M
PMID: 16438929
Journal: J Biol Chem. 2011 Jan 7;286(1):450-9.
Title: Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.
Author: Shakya, Arvind|Kang, Jinsuk|Chumley, Jeffrey|Williams, Matthew A|Tantin, Dean
PMID: 21051540
Journal: Nature. 2015 Apr 30;520(7549):697-701.
Title: TP53 loss creates therapeutic vulnerability in colorectal cancer.
Author: Liu, Yunhua|Zhang, Xinna|Han, Cecil|Wan, Guohui|Huang, Xingxu|Ivan, Cristina|Jiang, Dahai|Rodriguez-Aguayo, Cristian|Lopez-Berestein, Gabriel|Rao, Pulivarthi H|Maru, Dipen M|Pahl, Andreas|He, Xiaoming|Sood, Anil K|Ellis, Lee M|Anderl, Jan|Lu, Xiongbin
PMID: 25901683
Journal: Nat Rev Clin Oncol. 2015 Jul;12(7):374.
Title: Colorectal cancer: POLR2A deletion with TP53 opens a window of opportunity for therapy.
Author: Errico, Alessia
PMID: 25985938
Journal: Technol Cancer Res Treat. 2016 Dec;15(6):729-731.
Title: Anticancer Opportunity Created by Loss of Tumor Suppressor Genes.
Author: Hui-Ying, Xue|Da-Hong, Zhang|Li-Juan, Ji|Xiao-Jie, Lu
PMID: 26376693