Primary Site >> Stomach Cancer

Gene >> PLAUR

Journal: J Clin Oncol. 1995 Aug;13(8):2084-93.
Title: Tumor-associated proteolysis and prognosis: new functional risk factors in gastric cancer defined by the urokinase-type plasminogen activator system.
Author: Heiss, M M|Babic, R|Allgayer, H|Gruetzner, K U|Jauch, K W|Loehrs, U|Schildberg, F W
PMID: 7636552
Journal: J Korean Med Sci. 1996 Feb;11(1):33-7.
Title: Expression of urokinase-type plasminogen activator, its receptor, and its inhibitor in gastric adenocarcinoma tissues.
Author: Hong, S I|Park, I C|Son, Y S|Lee, S H|Kim, B G|Lee, J I|Lee, T W|Kook, Y H|Min, Y I|Hong, W S
PMID: 8703368
Journal: J Histochem Cytochem. 1997 Feb;45(2):203-12.
Title: Immunocytochemical phenotyping of disseminated tumor cells in bone marrow by uPA receptor and CK18: investigation of sensitivity and specificity of an immunogold/alkaline phosphatase double staining protocol.
Author: Allgayer, H|Heiss, M M|Riesenberg, R|Babic, R|Jauch, K W|Schildberg, F W
PMID: 9016310
Journal: Clin Exp Metastasis. 1997 Jul;15(4):418-25.
Title: Urokinase-type plasminogen activator receptor in gastric cancer: tissue expression and prognostic role.
Author: Plebani, M|Herszenyi, L|Carraro, P|De Paoli, M|Roveroni, G|Cardin, R|Tulassay, Z|Naccarato, R|Farinati, F
PMID: 9219730
Journal: Oncol Rep. 1997 Nov-Dec;4(6):1229-34.
Title: Correlation between expression of urokinase-type plasminogen activator receptor and metastasis in gastric carcinoma.
Author: Yonemura, Y|Nojima, N|Kawamura, T|Ajisaka, H|Taniguchi, K|Fujimura, T|Fujita, H|Bandou, E|Fushida, S|Endou, Y|Obata, T|Sasaki, T
PMID: 21590227
Journal: Clin Exp Metastasis. 1998 Jan;16(1):62-73.
Title: Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Author: Allgayer, H|Babic, R|Grutzner, K U|Beyer, B C|Tarabichi, A|Schildberg, F W|Heiss, M M
PMID: 9502078
Journal: Cancer. 1998 Jun 1;82(11):2112-22.
Title: The relation between the growth patterns of gastric carcinoma and the expression of hepatocyte growth factor receptor (c-met), autocrine motility factor receptor, and urokinase-type plasminogen activator receptor.
Author: Taniguchi, K|Yonemura, Y|Nojima, N|Hirono, Y|Fushida, S|Fujimura, T|Miwa, K|Endo, Y|Yamamoto, H|Watanabe, H
PMID: 9610690
Journal: J Gastroenterol Hepatol. 1998 Sep;13(9):936-44.
Title: Expression of urokinase-type plasminogen activator receptor and plasminogen activator inhibitor-1 in gastric cancer.
Author: Kawasaki, K|Hayashi, Y|Wang, Y|Suzuki, S|Morita, Y|Nakamura, T|Narita, K|Doe, W|Itoh, H|Kuroda, Y
PMID: 9794194
Journal: Expert Opin Investig Drugs. 1998 Mar;7(3):391-403.
Title: Urokinase receptor antagonists: novel agents for the treatment of cancer.
Author: Weidle, U H|Konig, B
PMID: 15991980
Journal: Int J Cancer. 1999 Feb 19;84(1):74-9.
Title: Differing expression of MMPs-1 and -9 and urokinase receptor between diffuse- and intestinal-type gastric carcinoma.
Author: Migita, T|Sato, E|Saito, K|Mizoi, T|Shiiba, K|Matsuno, S|Nagura, H|Ohtani, H
PMID: 9988236
Journal: Int J Oncol. 1999 Oct;15(4):617-23.
Title: CD87-positive tumor cells in bone marrow aspirates identified by confocal laser scanning fluorescence microscopy.
Author: Noack, F|Helmecke, D|Rosenberg, R|Thorban, S|Nekarda, H|Fink, U|Lewald, J|Stich, M|Schutze, K|Harbeck, N|Magdolen, V|Graeff, H|Schmitt, M
PMID: 10493940
Journal: Int J Oncol. 2000 Nov;17(5):1001-5.
Title: Urokinase type plasminogen activator and its receptor regulate the invasive potential of gastric cancer cell lines.
Author: Okusa, Y|Ichikura, T|Mochizuki, H|Shinomiya, N
PMID: 11029504
Journal: Jpn J Cancer Res. 2002 Feb;93(2):151-6.
Title: Overexpression of urokinase-type plasminogen activator in human gastric cancer cell line (AGS) induces tumorigenicity in severe combined immunodeficient mice.
Author: Choi, Yang-Kyu|Yoon, Byung-Il|Kook, Yoon-Hoh|Won, Young-Suk|Kim, Jin-Hyun|Lee, Chul-Ho|Hyun, Byung-Hwa|Oh, Goo-Taeg|Sipley, John|Kim, Dae-Yong
PMID: 11856478
Journal: Cancer Sci. 2003 Jan;94(1):43-9.
Title: Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer.
Author: Kaneko, Takeshi|Konno, Hiroyuki|Baba, Megumi|Tanaka, Tatsuo|Nakamura, Satoshi
PMID: 12708473
Journal: Cancer Res Treat. 2003 Feb;35(1):9-15.
Title: Overexpression of c-met Protein in Gastric Cancer and Role of uPAR as a Therapeutic Target.
Author: Oh, Hyun A|Lee, Gu|Kang, Hee Jung|Kim, Yong Gil|Bae, Sung Hwa|Lee, Jae Lyun|Lee, Kyung Hee|Hyun, Myung Soo|Kim, Dong Suk
PMID: 26680909
Journal: Cancer Res. 2003 Aug 1;63(15):4648-55.
Title: Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system.
Author: Lee, Dong Hoon|Yang, Young|Lee, Soon Jung|Kim, Kun-Yong|Koo, Tae Hyeon|Shin, Sun Mi|Song, Kyu Sang|Lee, Young Ho|Kim, Yung-Jin|Lee, Jung Joon|Choi, Inpyo|Lee, Jeong-Hyung
PMID: 12907645
Journal: Oncology. 2004;66(3):210-7.
Title: Relationship between urokinase-type plasminogen receptor, interleukin-8 gene expression and clinicopathological features in gastric cancer.
Author: Lee, Kyung Hee|Bae, Sung Hwa|Lee, Jae Lyun|Hyun, Myung Soo|Kim, Sang Hoon|Song, Sun Kyo|Kim, Hee Sun
PMID: 15218312
Journal: Int J Oncol. 2005 Jun;26(6):1669-74.
Title: Extracellular signal-regulated kinase and AP-1 pathways are involved in reactive oxygen species-induced urokinase plasminogen activator receptor expression in human gastric cancer cells.
Author: Kim, Mi H|Cho, Hyung S|Jung, Min|Hong, Min H|Lee, Sam K|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 15870884
Journal: Scand J Gastroenterol. 2005 Jul;40(7):783-93.
Title: Expressions of urokinase-type plasminogen activator, its receptor and plasminogen activator inhibitor-1 in gastric cancer cells and effects of Helicobacter pylori.
Author: Iwamoto, Junichi|Mizokami, Yuji|Takahashi, Kimiko|Nakajima, Kazuhiko|Ohtsubo, Toshiya|Miura, Syuhei|Narasaka, Toshiaki|Takeyama, Hiroki|Omata, Takayuki|Shimokobe, Koichi|Ito, Masanori|Takehara, Hisashi|Matsuoka, Takeshi
PMID: 16109653
Journal: Korean J Intern Med. 2006 Mar;21(1):20-7.
Title: Hepatocyte growth factor/c-met signaling in regulating urokinase plasminogen activator in human stomach cancer: A potential therapeutic target for human stomach cancer.
Author: Lee, Kyung Hee|Choi, Eun Young|Hyun, Myung Soo|Jang, Byung Ik|Kim, Tae Nyeun|Kim, Sang Woon|Song, Sun Kyo|Kim, Jung Hye|Kim, Jae-Ryong
PMID: 16646560
Journal: World J Gastroenterol. 2006 Jul 7;12(25):3970-6.
Title: Correlative studies on uPA mRNA and uPAR mRNA expression with vascular endothelial growth factor, microvessel density, progression and survival time of patients with gastric cancer.
Author: Zhang, Li|Zhao, Zhong-Sheng|Ru, Guo-Qing|Ma, Jie
PMID: 16810742
Journal: Int J Mol Med. 2007 Apr;19(4):689-97.
Title: Helicobacter pylori stimulates urokinase plasminogen activator receptor expression and cell invasiveness through reactive oxygen species and NF-kappaB signaling in human gastric carcinoma cells.
Author: Kim, Mi H|Yoo, Hyung S|Kim, Mi Y|Jang, Hee J|Baek, Min K|Kim, Hyeong R|Kim, Kyung K|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 17334646
Journal: Exp Cell Res. 2007 Apr 1;313(6):1181-91. Epub 2007 Feb 2.
Title: Hypoxia-inducible factor 1alpha regulates lung adenocarcinoma cell invasion.
Author: Shyu, Kou-Gi|Hsu, Feng-Lin|Wang, Ming Jen|Wang, Bao-Wei|Lin, Shankung
PMID: 17335808
Journal: Anticancer Res. 2007 Sep-Oct;27(5A):3411-7.
Title: Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells.
Author: Chang, Hee J|Kim, Mi H|Baek, Min K|Park, Jung S|Chung, Ik J|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 17970088
Journal: Cancer Biol Ther. 2008 May;7(5):651-9. Epub 2008 May 28.
Title: Inhibition of tumor growth and metastasis by ATF-Fc, an engineered antibody targeting urokinase receptor.
Author: Hu, Xian-Wen|Duan, Hai-Feng|Gao, Li-Hua|Pan, Shu-Yuan|Li, Yong-Mei|Xi, Yongyi|Zhao, Su-Rong|Yin, Liang|Li, Jin-Feng|Chen, Hui-Peng|Wu, Chu-Tse
PMID: 18245952
Journal: Oncol Rep. 2008 Dec;20(6):1569-75.
Title: EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells.
Author: Baek, Min K|Kim, Mi H|Jang, Hee J|Park, Jung S|Chung, Ik J|Shin, Boo A|Ahn, Bong W|Jung, Young D
PMID: 19020743
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G431-41.
Title: Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells.
Author: Kenny, Susan|Duval, Cedric|Sammut, Stephen J|Steele, Islay|Pritchard, D Mark|Atherton, John C|Argent, Richard H|Dimaline, Rod|Dockray, Graham J|Varro, Andrea
PMID: 18599586
Journal: J Cell Biochem. 2008 Jun 1;104(3):1102-12.
Title: Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells.
Author: Kim, Mi Ha|Park, Jung Sun|Chang, Hee Jung|Baek, Min Kyung|Kim, Hyeong Rok|Shin, Boo Ahn|Ahn, Bong Whan|Jung, Young Do
PMID: 18247343
Journal: Helicobacter. 2008 Jun;13(3):174-82.
Title: The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pylori-induced urokinase-type plasminogen activator system in the gastric cancer cells.
Author: Iwamoto, Junichi|Mizokami, Yuji|Takahashi, Kimiko|Matsuoka, Takeshi|Matsuzaki, Yasushi
PMID: 18466392
Journal: Br J Cancer. 2009 Jan 13;100(1):153-9.
Title: Expression of uPAR mRNA in peripheral blood is a favourite marker for metastasis in gastric cancer cases.
Author: Kita, Y|Fukagawa, T|Mimori, K|Kosaka, Y|Ishikawa, K|Aikou, T|Natsugoe, S|Sasako, M|Mori, M
PMID: 19050704
Journal: Carcinogenesis. 2011 Feb;32(2):175-81.
Title: MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-kappaB signals in gastric cancer cells.
Author: Park, Jung Sun|Park, Ji Hye|Khoi, Pham Ngoc|Joo, Young Eun|Jung, Young Do
PMID: 21081472
Journal: Cancer Prev Res (Phila). 2011 Sep;4(9):1426-35.
Title: 17beta-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice.
Author: Sheh, Alexander|Ge, Zhongming|Parry, Nicola M A|Muthupalani, Sureshkumar|Rager, Julia E|Raczynski, Arkadiusz R|Mobley, Melissa W|McCabe, Amanda F|Fry, Rebecca C|Wang, Timothy C|Fox, James G
PMID: 21680705
Journal: Int J Cancer. 2012 Mar 15;130(6):1357-66.
Title: A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
Author: Torti, Davide|Sassi, Francesco|Galimi, Francesco|Gastaldi, Stefania|Perera, Timothy|Comoglio, Paolo M|Trusolino, Livio|Bertotti, Andrea
PMID: 21500189
Journal: Int J Cancer. 2012 Aug 15;131(4):E329-36.
Title: Urokinase plasminogen activator receptor on invasive cancer cells: a prognostic factor in distal gastric adenocarcinoma.
Author: Alpizar-Alpizar, Warner|Christensen, Ib Jarle|Santoni-Rugiu, Eric|Skarstein, Arne|Ovrebo, Kjell|Illemann, Martin|Laerum, Ole Didrik
PMID: 21901747
Journal: Int J Oncol. 2012 Sep;41(3):839-48.
Title: Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting betacatenin signaling.
Author: Kundu, Juthika|Wahab, S M Riajul|Kundu, Joydeb Kumar|Choi, Yoon-La|Erkin, Ozgur Cem|Lee, Hun Seok|Park, Sang Gyu|Shin, Young Kee
PMID: 22710759
Journal: Br J Cancer. 2013 Jun 25;108(12):2557-64.
Title: Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer.
Author: Zhao, J|Liang, Q|Cheung, K-F|Kang, W|Dong, Y|Lung, R W-M|Tong, J H-M|To, K-F|Sung, J J Y|Yu, J
PMID: 23722468
Journal: Nanoscale. 2013 Sep 7;5(17):8192-201.
Title: Targeting of peptide conjugated magnetic nanoparticles to urokinase plasminogen activator receptor (uPAR) expressing cells.
Author: Hansen, Line|Larsen, Esben Kjaer Unmack|Nielsen, Erik Holm|Iversen, Frank|Liu, Zhuo|Thomsen, Karen|Pedersen, Michael|Skrydstrup, Troels|Nielsen, Niels Chr|Ploug, Michael|Kjems, Jorgen
PMID: 23835641
Journal: PLoS One. 2013 Dec 27;8(12):e81423.
Title: IGFBP3, a transcriptional target of homeobox D10, is correlated with the prognosis of gastric cancer.
Author: Xue, Meng|Fang, Yanfei|Sun, Guoming|Zhuo, Wei|Zhong, Jing|Qian, Cuijuan|Wang, Lan|Wang, Liangjing|Si, Jianmin|Chen, Shujie
PMID: 24386080
Journal: Int J Oncol. 2014 Oct;45(4):1760-8.
Title: Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-kappaB, and AP-1 signaling pathways.
Author: Khoi, Pham Ngoc|Xia, Yong|Lian, Sen|Kim, Ho Dong|Kim, Do Hyun|Joo, Young Eun|Chay, Kee-Oh|Kim, Kyung Keun|Jung, Young Do
PMID: 25069788
Journal: Adv Clin Exp Med. 2014 Nov-Dec;23(6):959-67.
Title: Soluble urokinase-type plasminogen activator receptor and ferritin concentration in patients with advanced alimentary tract carcinoma. Relationship to localization, surgical treatment and the stage of the disease--preliminary report.
Author: Usnarska-Zubkiewicz, Lidia|Strutynska-Karpinska, Marta|Zubkiewicz-Kucharska, Agnieszka|Zarebski, Pawel|Grabowski, Krzysztof
PMID: 25618124
Journal: Oncol Rep. 2015 May;33(5):2484-94.
Title: Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches.
Author: Su, Bo|Su, Jian|He, Hui|Wu, Youhua|Xia, Hong|Zeng, Xi|Dai, Wenxiang|Ai, Xiaohong|Ling, Hui|Jiang, Hao|Su, Qi
PMID: 25812569
Journal: Onco Targets Ther. 2015 Jun 19;8:1503-9.
Title: Prognostic role of urokinase plasminogen activator receptor in gastric and colorectal cancer: A systematic review and meta-analysis.
Author: Guo, Hong|Ling, Chun|Ma, Yun-Yun|Zhou, Lan-Xia|Zhao, Li
PMID: 26150727
Journal: Oncol Lett. 2016 Jun;11(6):4208-4216.
Title: Effect of urokinase-type plasminogen activator system in gastric cancer with peritoneal metastasis.
Author: Ding, Youcheng|Zhang, Hui|Lu, Aiguo|Zhou, Zhuqing|Zhong, Mingan|Shen, Dongwei|Wang, Xujing|Zhu, Zhenggang
PMID: 27313768
Journal: Mol Carcinog. 2017 Feb;56(2):664-680.
Title: Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells.
Author: Lian, Sen|Xia, Yong|Ung, Trong Thuan|Khoi, Pham Ngoc|Yoon, Hyun Joong|Lee, Sam Gyu|Kim, Kyung Keun|Jung, Young Do
PMID: 27377703
Journal: J Cancer Res Ther. 2017 Apr-Jun;13(2):246-251.
Title: In vitro activity of probiotic Lactobacillus reuteri against gastric cancer progression by downregulation of urokinase plasminogen activator/urokinase plasminogen activator receptor gene expression.
Author: Rasouli, Bahareh Sadat|Ghadimi-Darsajini, Ali|Nekouian, Reza|Iragian, Gholam-Reza
PMID: 28643742
Journal: Oncol Rep. 2017 Oct;38(4):2325-2334.
Title: EGF-induced urokinase plasminogen activator receptor promotes epithelial to mesenchymal transition in human gastric cancer cells.
Author: Wang, Pingping|Ma, Maoyuan|Zhang, Shanhui
PMID: 28849196
Journal: Clin Epigenetics. 2017 Oct 17;9:114.
Title: MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.
Author: Sandoval-Borquez, Alejandra|Polakovicova, Iva|Carrasco-Veliz, Nicolas|Lobos-Gonzalez, Lorena|Riquelme, Ismael|Carrasco-Avino, Gonzalo|Bizama, Carolina|Norero, Enrique|Owen, Gareth I|Roa, Juan C|Corvalan, Alejandro H
PMID: 29075357
Journal: Integr Cancer Ther. 2018 Jun;17(2):511-523.
Title: Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-kappab, PKC-delta, ERK1/2, and AMPKalpha.
Author: Li, Hai|Chen, Chen
PMID: 28627240
Journal: Zhonghua Zhong Liu Za Zhi. 2018 Aug 23;40(8):580-586.
Title: [Effects of MTA1 on biological behaviors of gastric cancer cells].
Author: Wang, J S|Qian, H L|Wang, H J|Xu, D K
PMID: 30139027