Primary Site >> Liver Cancer

Gene >> PFKFB4

Journal: Acta Biochim Pol. 2005;52(4):881-8. Epub 2005 Jul 11.
Title: Expression and hypoxia-responsiveness of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 in mammary gland malignant cell lines.
Author: Minchenko, Oleksandr H|Opentanova, Iryna L|Ogura, Tsutomu|Minchenko, Dmytro O|Komisarenko, Sergiy V|Caro, Jaime|Esumi, Hiroyasu
PMID: 16025159
Journal: Biochim Biophys Acta. 2011 Oct;1814(10):1340-8.
Title: Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway.
Author: Jeon, Young Keul|Yoo, Dong Ryeol|Jang, Yun Ho|Jang, Se Young|Nam, Myeong Jin
PMID: 21640852
Journal: Oncotarget. 2016 Nov 22;7(47):76984-76994.
Title: Phosphorylation of PPARgamma at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4.
Author: Shu, Yuxin|Lu, Yan|Pang, Xiaojuan|Zheng, Wei|Huang, Yahong|Li, Jiahong|Ji, Jianguo|Zhang, Can|Shen, Pingping
PMID: 27769068