Primary Site >> Pancreatic Cancer

Gene >> NRP1

Journal: Cancer. 2003 Aug 15;98(4):720-9.
Title: Expression and regulation of the novel vascular endothelial growth factor receptor neuropilin-1 by epidermal growth factor in human pancreatic carcinoma.
Author: Parikh, Alexander A|Liu, Wen Biao|Fan, Fan|Stoeltzing, Oliver|Reinmuth, Niels|Bruns, Christiane J|Bucana, Corazon D|Evans, Douglas B|Ellis, Lee M
PMID: 12910515
Journal: Am J Surg Pathol. 2004 Mar;28(3):347-56.
Title: Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract.
Author: Hansel, Donna E|Wilentz, Robert E|Yeo, Charles J|Schulick, Richard D|Montgomery, Elizabeth|Maitra, Anirban
PMID: 15104297
Journal: Cancer. 2004 Nov 15;101(10):2341-50.
Title: Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors.
Author: Li, Min|Yang, Hui|Chai, Hong|Fisher, William E|Wang, Xiaoping|Brunicardi, F Charles|Yao, Qizhi|Chen, Changyi
PMID: 15476280
Journal: Cancer Res. 2005 May 1;65(9):3664-70.
Title: Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors.
Author: Gray, Michael J|Wey, Jane S|Belcheva, Anna|McCarty, Marya F|Trevino, Jose G|Evans, Douglas B|Ellis, Lee M|Gallick, Gary E
PMID: 15867361
Journal: Br J Cancer. 2005 Jul 25;93(2):233-41.
Title: Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells.
Author: Wey, J S|Gray, M J|Fan, F|Belcheva, A|McCarty, M F|Stoeltzing, O|Somcio, R|Liu, W|Evans, D B|Klagsbrun, M|Gallick, G E|Ellis, L M
PMID: 15956974
Journal: Am J Surg. 2005 Nov;190(5):739-45.
Title: Effect of cyclophilin A on gene expression in human pancreatic cancer cells.
Author: Li, Min|Wang, Hao|Li, Fei|Fisher, William E|Chen, Changyi|Yao, Qizhi
PMID: 16226951
Journal: Cancer Biol Ther. 2007 Jul;6(7):1096-100.
Title: IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells.
Author: Feurino, Louis W|Zhang, Yuqing|Bharadwaj, Uddalak|Zhang, Rongxin|Li, Fei|Fisher, William E|Brunicardi, F Charles|Chen, Changyi|Yao, Qizhi|Min, L
PMID: 17568185
Journal: Int J Cancer. 2007 Dec 1;121(11):2421-33.
Title: Association of axon guidance factor semaphorin 3A with poor outcome in pancreatic cancer.
Author: Muller, Michael W|Giese, Nathalia A|Swiercz, Jakub M|Ceyhan, Guralp O|Esposito, Irene|Hinz, Ulf|Buchler, Peter|Giese, Thomas|Buchler, Markus W|Offermanns, Stefan|Friess, Helmut
PMID: 17631638
Journal: Cancer Biol Ther. 2010 Feb;9(3):236-42. Epub 2010 Feb 25.
Title: ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts.
Author: Zhang, Yuqing|Chen, Changyi|Yao, Qizhi|Li, Min
PMID: 20023433
Journal: Biochem Biophys Res Commun. 2011 Oct 14;414(1):60-6.
Title: Semaphorin 3A lytic hybrid peptide binding to neuropilin-1 as a novel anti-cancer agent in pancreatic cancer.
Author: Ueyama, Hanae|Horibe, Tomohisa|Nakajima, Oumi|Ohara, Koji|Kohno, Masayuki|Kawakami, Koji
PMID: 21945444
Journal: Exp Mol Med. 2013 Jun 7;45:e26.
Title: Functional proteomics, human genetics and cancer biology of GIPC family members.
Author: Katoh, Masaru
PMID: 23743496
Journal: Br J Cancer. 2014 Mar 18;110(6):1481-7.
Title: Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1.
Author: Akashi, Y|Oda, T|Ohara, Y|Miyamoto, R|Kurokawa, T|Hashimoto, S|Enomoto, T|Yamada, K|Satake, M|Ohkohchi, N
PMID: 24556620
Journal: Curr Mol Med. 2014 Mar;14(3):316-27.
Title: miR-1247 is correlated with prognosis of pancreatic cancer and inhibits cell proliferation by targeting neuropilins.
Author: Shi, S|Lu, Y|Qin, Y|Li, W|Cheng, H|Xu, Y|Xu, J|Long, J|Liu, L|Liu, C|Yu, X
PMID: 24588767
Journal: Oncol Rep. 2014 Aug;32(2):513-22.
Title: PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/beta-catenin pathway by phosphorylation and degradation of beta-catenin.
Author: Wu, Meng-Yao|Xie, Xin|Xu, Ze-Kuan|Xie, Li|Chen, Zheng|Shou, Liu-Mei|Gong, Fei-Ran|Xie, Yu-Feng|Li, Wei|Tao, Min
PMID: 24926961
Journal: Curr Mol Med. 2016;16(4):394-403.
Title: VEGF Promotes Glycolysis in Pancreatic Cancer via HIF1alpha Up-Regulation.
Author: Shi, S|Xu, J|Zhang, B|Ji, S|Xu, W|Liu, J|Jin, K|Liang, D|Liang, C|Liu, L|Liu, C|Qin, Y|Yu, X
PMID: 26980697
Journal: J Clin Invest. 2017 May 1;127(5):2007-2018.
Title: Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer.
Author: Liu, Xiangsheng|Lin, Paulina|Perrett, Ian|Lin, Joshua|Liao, Yu-Pei|Chang, Chong Hyun|Jiang, Jinhong|Wu, Nanping|Donahue, Timothy|Wainberg, Zev|Nel, Andre E|Meng, Huan
PMID: 28414297
Journal: Sci Transl Med. 2018 May 23;10(442). pii: 10/442/eaah4807.
Title: A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.
Author: Gioelli, Noemi|Maione, Federica|Camillo, Chiara|Ghitti, Michela|Valdembri, Donatella|Morello, Noemi|Darche, Marie|Zentilin, Lorena|Cagnoni, Gabriella|Qiu, Yaqi|Giacca, Mauro|Giustetto, Maurizio|Paques, Michel|Cascone, Ilaria|Musco, Giovanna|Tamagnone, Luc
PMID: 29794061
Journal: J Pathol. 2018 Jul 20.
Title: VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival.
Author: Morin, Eric|Sjoberg, Elin|Tjomsland, Vegard|Testini, Chiara|Lindskog, Cecilia|Franklin, Oskar|Sund, Malin|Ohlund, Daniel|Kiflemariam, Sara|Sjoblom, Tobias|Claesson-Welsh, Lena
PMID: 30027561
Journal: Cancer Med. 2018 Sep 14.
Title: Jack of many trades: Multifaceted role of neuropilins in pancreatic cancer.
Author: Matkar, Pratiek N|Jong, Eric D|Ariyagunarajah, Ramya|Prud'homme, Gerald J|Singh, Krishna K|Leong-Poi, Howard
PMID: 30216699