Literatures

Primary Site >> Colorectal Cancer

Gene >> NRAS

1.
Journal:	Jpn J Cancer Res. 1986 Jul;77(7):639-47.
Title:	Activated N-ras in a human rectal carcinoma cell line associated with clonal homozygosity in myb locus-restriction fragment polymorphism.
Author:	Yuasa, Y\|Reddy, E P\|Rhim, J S\|Tronick, S R\|Aaronson, S A
PMID:	3017909

2.
Journal:	N Engl J Med. 1987 Oct 8;317(15):929-35.
Title:	Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung.
Author:	Rodenhuis, S\|van de Wetering, M L\|Mooi, W J\|Evers, S G\|van Zandwijk, N\|Bos, J L
PMID:	3041218

3.
Journal:	Leukemia. 1988 Feb;2(2):91-3.
Title:	12th codon mutation resulting in c-N-ras activation in acute myelogenous leukemia.
Author:	Needleman, S W\|Devine, S E\|Kraus, M H
PMID:	3278172

4.
Journal:	Exp Cell Res. 1989 Sep;184(1):16-27.
Title:	Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells.
Author:	Stoddart, J H\|Lane, M A\|Niles, R M
PMID:	2676572

5.
Journal:	Cancer Res. 1991 Aug 1;51(15):4102-6.
Title:	Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations.
Author:	Hollstein, M C\|Peri, L\|Mandard, A M\|Welsh, J A\|Montesano, R\|Metcalf, R A\|Bak, M\|Harris, C C
PMID:	1855226

6.
Journal:	Mol Carcinog. 1993;8(1):44-8.
Title:	Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis.
Author:	Kakiuchi, H\|Ushijima, T\|Ochiai, M\|Imai, K\|Ito, N\|Yachi, A\|Sugimura, T\|Nagao, M
PMID:	8352890

7.
Journal:	Int J Oncol. 1993 Feb;2(2):123-34.
Title:	Mutations in the p53 suppressor gene do not correlate with C-k-ras oncogene mutations in colorectal-cancer.
Author:	Peinado, M\|Fernandezrenart, M\|Capella, G\|Wilson, L\|Perucho, M
PMID:	21573526

8.
Journal:	Tumori. 1995 May-Jun;81(3 Suppl):7-11.
Title:	Ras oncogene activation in benign and malignant colorectal tumours.
Author:	Spandidos, D A\|Glarakis, I S\|Kotsinas, A\|Ergazaki, M\|Kiaris, H
PMID:	7571058

9.
Journal:	Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6665-70.
Title:	Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells.
Author:	Plattner, R\|Anderson, M J\|Sato, K Y\|Fasching, C L\|Der, C J\|Stanbridge, E J
PMID:	8692875

10.
Journal:	Int J Cancer. 1997 May 29;71(5):767-75.
Title:	N-ras protein: frequent quantitative and qualitative changes occur in human colorectal carcinomas.
Author:	Kim, K\|Kuo, T\|Cai, J\|Shuja, S\|Murnane, M J
PMID:	9180144

11.
Journal:	Zhonghua Nei Ke Za Zhi. 1997 Sep;36(9):595-8.
Title:	[Detection of ras gene mutation in various stages of gastric cancer by PCR/RFLP SSCP and DNA sequencing].
Author:	Hao, Y\|Zhang, J\|Lu, Y
PMID:	10436968

12.
Journal:	Int J Cancer. 1998 Aug 21;79(4):324-33.
Title:	Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas.
Author:	Kim, K\|Cai, J\|Shuja, S\|Kuo, T\|Murnane, M J
PMID:	9699522

13.
Journal:	Int J Cancer. 2000 Feb 1;85(3):438-45.
Title:	Quercetin inhibits p21-RAS expression in human colon cancer cell lines and in primary colorectal tumors.
Author:	Ranelletti, F O\|Maggiano, N\|Serra, F G\|Ricci, R\|Larocca, L M\|Lanza, P\|Scambia, G\|Fattorossi, A\|Capelli, A\|Piantelli, M
PMID:	10652438

14.
Journal:	Cancer Res. 2005 Mar 15;65(6):2085-8.
Title:	Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells.
Author:	Stearns, Mark\|Tran, Jordan\|Francis, Mary Kay\|Zhang, Hong\|Sell, Christian
PMID:	15781617

15.
Journal:	Cancer Biol Ther. 2006 Aug;5(8):928-32. Epub 2006 Aug 1.
Title:	Recurrent KRAS codon 146 mutations in human colorectal cancer.
Author:	Edkins, Sarah\|O'Meara, Sarah\|Parker, Adrian\|Stevens, Claire\|Reis, Marcelo\|Jones, Sian\|Greenman, Chris\|Davies, Helen\|Dalgliesh, Gillian\|Forbes, Simon\|Hunter, Chris\|Smith, Raffaella\|Stephens, Philip\|Goldstraw, Peter\|Nicholson, Andrew\|Chan, Tsun Leung\|Velcul
PMID:	16969076

16.
Journal:	J Cell Physiol. 2007 Mar;210(3):740-9.
Title:	Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium.
Author:	Keller, Jeffrey W\|Franklin, Jeffrey L\|Graves-Deal, Ramona\|Friedman, David B\|Whitwell, Corbin W\|Coffey, Robert J
PMID:	17133351

17.
Journal:	Mol Cancer Res. 2007 Feb;5(2):195-201.
Title:	Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.
Author:	Hollestelle, Antoinette\|Elstrodt, Fons\|Nagel, Jord H A\|Kallemeijn, Wouter W\|Schutte, Mieke
PMID:	17314276

18.
Journal:	Nat Genet. 2008 May;40(5):600-8.
Title:	Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Author:	Haigis, Kevin M\|Kendall, Krystle R\|Wang, Yufang\|Cheung, Ann\|Haigis, Marcia C\|Glickman, Jonathan N\|Niwa-Kawakita, Michiko\|Sweet-Cordero, Alejandro\|Sebolt-Leopold, Judith\|Shannon, Kevin M\|Settleman, Jeffrey\|Giovannini, Marco\|Jacks, Tyler
PMID:	18372904

19.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title:	In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author:	Ikediobi, Ogechi N\|Reimers, Mark\|Durinck, Steffen\|Blower, Paul E\|Futreal, Andrew P\|Stratton, Michael R\|Weinstein, John N
PMID:	18524847

20.
Journal:	PLoS One. 2009 May 27;4(5):e5717.
Title:	Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.
Author:	Jaiswal, Bijay S\|Janakiraman, Vasantharajan\|Kljavin, Noelyn M\|Eastham-Anderson, Jeffrey\|Cupp, James E\|Liang, Yuxin\|Davis, David P\|Hoeflich, Klaus P\|Seshagiri, Somasekar
PMID:	19492075

21.
Journal:	Mutat Res. 2009 Nov 2;670(1-2):96-8.
Title:	Genetic pathways to colorectal cancer.
Author:	Lea, Isabel A\|Jackson, Marcus A\|Dunnick, June K
PMID:	19576232

22.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1244-52.
Title:	Oncogenic activating mutations are associated with local copy gain.
Author:	Modrek, Barmak\|Ge, Lin\|Pandita, Ajay\|Lin, Eva\|Mohan, Sankar\|Yue, Peng\|Guerrero, Steve\|Lin, William M\|Pham, Thinh\|Modrusan, Zora\|Seshagiri, Somasekar\|Stern, Howard M\|Waring, Paul\|Garraway, Levi A\|Chant, John\|Stokoe, David\|Cavet, Guy
PMID:	19671679

23.
Journal:	PLoS One. 2010 Jan 21;5(1):e8802.
Title:	Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes.
Author:	Lurkin, Irene\|Stoehr, Robert\|Hurst, Carolyn D\|van Tilborg, Angela A G\|Knowles, Margaret A\|Hartmann, Arndt\|Zwarthoff, Ellen C
PMID:	20098682

24.
Journal:	BMC Cancer. 2010 Mar 16;10:101.
Title:	A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
Author:	Fumagalli, Debora\|Gavin, Patrick G\|Taniyama, Yusuke\|Kim, Seung-Il\|Choi, Hyun-Joo\|Paik, Soonmyung\|Pogue-Geile, Katherine L
PMID:	20233444

25.
Journal:	Neoplasia. 2010 Jun;12(6):443-52.
Title:	Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.
Author:	van Houdt, Winan J\|Hoogwater, Frederik J H\|de Bruijn, Menno T\|Emmink, Benjamin L\|Nijkamp, Maarten W\|Raats, Danielle A E\|van der Groep, Petra\|van Diest, Paul\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	20563247

26.
Journal:	Diagn Mol Pathol. 2010 Sep;19(3):157-63.
Title:	NRAS mutations are rare in colorectal cancer.
Author:	Irahara, Natsumi\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Yan, Liying\|Dias-Santagata, Dora\|Iafrate, Anthony John\|Fuchs, Charles S\|Haigis, Kevin M\|Ogino, Shuji
PMID:	20736745

27.
Journal:	Clin Cancer Res. 2011 Mar 1;17(5):1122-30.
Title:	KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.
Author:	Tie, Jeanne\|Lipton, Lara\|Desai, Jayesh\|Gibbs, Peter\|Jorissen, Robert N\|Christie, Michael\|Drummond, Katharine J\|Thomson, Benjamin N J\|Usatoff, Valery\|Evans, Peter M\|Pick, Adrian W\|Knight, Simon\|Carne, Peter W G\|Berry, Roger\|Polglase, Adrian\|McMurrick, Paul
PMID:	21239505

28.
Journal:	Genes Chromosomes Cancer. 2011 May;50(5):307-12.
Title:	Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
Author:	Vaughn, Cecily P\|Zobell, Scott D\|Furtado, Larissa V\|Baker, Christine L\|Samowitz, Wade S
PMID:	21305640

29.
Journal:	Cancer J. 2011 Mar-Apr;17(2):114-26.
Title:	Molecular predictors of response to chemotherapy in colorectal cancer.
Author:	Dienstmann, Rodrigo\|Vilar, Eduardo\|Tabernero, Josep
PMID:	21427555

30.
Journal:	Lancet. 2011 Jun 18;377(9783):2103-14.
Title:	Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.
Author:	Maughan, Timothy S\|Adams, Richard A\|Smith, Christopher G\|Meade, Angela M\|Seymour, Matthew T\|Wilson, Richard H\|Idziaszczyk, Shelley\|Harris, Rebecca\|Fisher, David\|Kenny, Sarah L\|Kay, Edward\|Mitchell, Jenna K\|Madi, Ayman\|Jasani, Bharat\|James, Michelle D\|Brid
PMID:	21641636

31.
Journal:	J Mol Diagn. 2011 Jul;13(4):436-45.
Title:	KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers diagnostic and therapeutic implications.
Author:	Balschun, Katharina\|Haag, Jochen\|Wenke, Ann-Kathrin\|von Schonfels, Witigo\|Schwarz, Nicolas T\|Rocken, Christoph
PMID:	21704278

32.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):279-89.
Title:	Development of molecular biomarkers in individualized treatment of colorectal cancer.
Author:	De Mattos-Arruda, Leticia\|Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	21729679

33.
Journal:	PLoS One. 2011;6(7):e22769.
Title:	PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.
Author:	Janku, Filip\|Lee, J Jack\|Tsimberidou, Apostolia M\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Fu, Siqing\|Luthra, Rajyalakshmi\|Garrido-Laguna, Ignacio\|Kurzrock, Razelle
PMID:	21829508

34.
Journal:	Cancer Discov. 2011 Nov;1(6):508-23.
Title:	A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Author:	Bertotti, Andrea\|Migliardi, Giorgia\|Galimi, Francesco\|Sassi, Francesco\|Torti, Davide\|Isella, Claudio\|Cora, Davide\|Di Nicolantonio, Federica\|Buscarino, Michela\|Petti, Consalvo\|Ribero, Dario\|Russolillo, Nadia\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alber
PMID:	22586653

35.
Journal:	Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):233-47.
Title:	Emerging role of cetuximab in the treatment of colorectal cancer.
Author:	Papa, Anselmo\|Rossi, Luigi\|Lo Russo, Giuseppe\|Giordani, Erika\|Spinelli, Gian Paolo\|Zullo, Angelo\|Petrozza, Vincenzo\|Tomao, Silverio
PMID:	22264223

36.
Journal:	Clin Cancer Res. 2012 May 1;18(9):2515-25.
Title:	Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Author:	Migliardi, Giorgia\|Sassi, Francesco\|Torti, Davide\|Galimi, Francesco\|Zanella, Eugenia R\|Buscarino, Michela\|Ribero, Dario\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alberto\|Risio, Mauro\|Capussotti, Lorenzo\|Marsoni, Silvia\|Di Nicolantonio, Federica\|Bardelli,
PMID:	22392911

37.
Journal:	Int J Biol Markers. 2012 Jan-Mar;27(1):27-33.
Title:	Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.
Author:	Bagadi, Sarita B\|Sanghvi, Meera\|Nair, Sudish B\|Das, Bibhu R
PMID:	22427190

38.
Journal:	J Clin Oncol. 2012 Aug 20;30(24):2956-62.
Title:	Comparative genomic analysis of primary versus metastatic colorectal carcinomas.
Author:	Vakiani, Efsevia\|Janakiraman, Manickam\|Shen, Ronglai\|Sinha, Rileen\|Zeng, Zhaoshi\|Shia, Jinru\|Cercek, Andrea\|Kemeny, Nancy\|D'Angelica, Michael\|Viale, Agnes\|Heguy, Adriana\|Paty, Philip\|Chan, Timothy A\|Saltz, Leonard B\|Weiser, Martin\|Solit, David B
PMID:	22665543

39.
Journal:	Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2127-33.
Title:	Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Author:	Ohashi, Kadoaki\|Sequist, Lecia V\|Arcila, Maria E\|Moran, Teresa\|Chmielecki, Juliann\|Lin, Ya-Lun\|Pan, Yumei\|Wang, Lu\|de Stanchina, Elisa\|Shien, Kazuhiko\|Aoe, Keisuke\|Toyooka, Shinichi\|Kiura, Katsuyuki\|Fernandez-Cuesta, Lynnette\|Fidias, Panos\|Yang, James Chi
PMID:	22773810

40.
Journal:	Oncotarget. 2012 Jul;3(7):700-8.
Title:	The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes.
Author:	Singhal, Ruchi\|Kandel, Eugene S
PMID:	22869096

41.
Journal:	Clin Cancer Res. 2012 Dec 1;18(23):6531-41.
Title:	Mutation profiling and microsatellite instability in stage II and III colon cancer: an assessment of their prognostic and oxaliplatin predictive value.
Author:	Gavin, Patrick G\|Colangelo, Linda H\|Fumagalli, Debora\|Tanaka, Noriko\|Remillard, Matthew Y\|Yothers, Greg\|Kim, Chungyeul\|Taniyama, Yusuke\|Kim, Seung Il\|Choi, Hyun Joo\|Blackmon, Nicole L\|Lipchik, Corey\|Petrelli, Nicholas J\|O'Connell, Michael J\|Wolmark, Norma
PMID:	23045248

42.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title:	[Predictive biomarkers for anti-EGFR antibodies].
Author:	Bando, Hideaki\|Yoshino, Takayuki
PMID:	23152013

43.
Journal:	Crit Rev Oncol Hematol. 2013 Jan;85(1):45-81.
Title:	Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations.
Author:	Custodio, Ana\|Feliu, Jaime
PMID:	22647972

44.
Journal:	Hum Pathol. 2013 May;44(5):829-36.
Title:	Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Author:	Bettstetter, Marcus\|Berezowska, Sabina\|Keller, Gisela\|Walch, Axel\|Feuchtinger, Annette\|Slotta-Huspenina, Julia\|Feith, Marcus\|Drecoll, Enken\|Hofler, Heinz\|Langer, Rupert
PMID:	23158210

45.
Journal:	J Pathol. 2013 Feb;229(3):441-8.
Title:	Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.
Author:	Domingo, Enric\|Ramamoorthy, Rajarajan\|Oukrif, Dahmane\|Rosmarin, Daniel\|Presz, Michal\|Wang, Haitao\|Pulker, Hannah\|Lockstone, Helen\|Hveem, Tarjei\|Cranston, Treena\|Danielsen, Havard\|Novelli, Marco\|Davidson, Brian\|Xu, Zheng-Zhou\|Molloy, Peter\|Johnstone, Elain
PMID:	23165447

46.
Journal:	Cancer Discov. 2013 Mar;3(3):294-307.
Title:	Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.
Author:	Wang, Yufang\|Velho, Sergia\|Vakiani, Efsevia\|Peng, Shouyong\|Bass, Adam J\|Chu, Gerald C\|Gierut, Jessica\|Bugni, James M\|Der, Channing J\|Philips, Mark\|Solit, David B\|Haigis, Kevin M
PMID:	23274911

47.
Journal:	Expert Opin Biol Ther. 2013 Feb;13(2):241-55.
Title:	Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.
Author:	Troiani, Teresa\|Zappavigna, Silvia\|Martinelli, Erika\|Addeo, Santolo R\|Stiuso, Paola\|Ciardiello, Fortunato\|Caraglia, Michele
PMID:	23281932

48.
Journal:	BMC Cancer. 2013 Feb 2;13:49.
Title:	Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
Author:	Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Xanthakis, Ioannis\|Sgouros, Joseph\|Televantou, Despina\|Kafiri, Georgia\|Tsamandas, Athanassios C\|Razis, Evangelia\|Galan
PMID:	23374602

49.
Journal:	Target Oncol. 2013 Sep;8(3):183-8.
Title:	Bevacizumab-based treatment in colorectal cancer with a NRAS Q61K mutation.
Author:	Janku, Filip\|Wheler, Jennifer J\|Hong, David S\|Kurzrock, Razelle
PMID:	23400451

50.
Journal:	Genet Med. 2013 Jul;15(7):517-27.
Title:	Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID:	23429431

51.
Journal:	Am J Surg. 2013 May;205(5):608-12; discussion 612.
Title:	Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry.
Author:	Gawlick, Ute\|Lu, Kim C\|Douthit, Miriam A\|Diggs, Brian S\|Schuff, Kathryn G\|Herzig, Daniel O\|Tsikitis, Vassiliki L
PMID:	23592171

52.
Journal:	Lancet Oncol. 2013 Jul;14(8):749-59.
Title:	Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Author:	Seymour, Matthew T\|Brown, Sarah R\|Middleton, Gary\|Maughan, Timothy\|Richman, Susan\|Gwyther, Stephen\|Lowe, Catherine\|Seligmann, Jennifer F\|Wadsley, Jonathan\|Maisey, Nick\|Chau, Ian\|Hill, Mark\|Dawson, Lesley\|Falk, Stephen\|O'Callaghan, Ann\|Benstead, Kim\|Chambe
PMID:	23725851

53.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4104-13.
Title:	Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/- cetuximab.
Author:	Smith, Christopher G\|Fisher, David\|Claes, Bart\|Maughan, Timothy S\|Idziaszczyk, Shelley\|Peuteman, Gilian\|Harris, Rebecca\|James, Michelle D\|Meade, Angela\|Jasani, Bharat\|Adams, Richard A\|Kenny, Sarah\|Kaplan, Richard\|Lambrechts, Diether\|Cheadle, Jeremy P
PMID:	23741067

54.
Journal:	Clin Chim Acta. 2013 Oct 21;425:1-2.
Title:	Companion-diagnostic testing limited to KRAS codons 12 and 13 misses 17% of potentially relevant RAS mutations in colorectal cancer.
Author:	Netzel, Brian C\|Grebe, Stefan K G
PMID:	23832066

55.
Journal:	Med Oncol. 2013;30(3):686.
Title:	Pattern of clinically relevant mutations in consecutive series of Russian colorectal cancer patients.
Author:	Yanus, Grigoriy A\|Belyaeva, Anna V\|Ivantsov, Alexandr O\|Kuligina, Ekatherina Sh\|Suspitsin, Evgeny N\|Mitiushkina, Natalia V\|Aleksakhina, Svetlana N\|Iyevleva, Aglaya G\|Zaitseva, Olga A\|Yatsuk, Olga S\|Gorodnova, Tatiana V\|Strelkova, Tatiana N\|Efremova, Sofia
PMID:	23943423

56.
Journal:	BMC Gastroenterol. 2013 Aug 19;13:129.
Title:	Morphological change of a laterally spreading rectal tumor over a short period.
Author:	Miyamoto, Hideaki\|Oono, Yasuhiro\|Fu, Kuang-l\|Ikematsu, Hiroaki\|Fujii, Satoshi\|Kojima, Takashi\|Yano, Tomonori\|Ochiai, Atsushi\|Sasaki, Yutaka\|Kaneko, Kazuhiro
PMID:	23957258

57.
Journal:	BMC Cancer. 2013 Sep 3;13:405.
Title:	Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.
Author:	Bando, Hideaki\|Yoshino, Takayuki\|Shinozaki, Eiji\|Nishina, Tomohiro\|Yamazaki, Kentaro\|Yamaguchi, Kensei\|Yuki, Satoshi\|Kajiura, Shinya\|Fujii, Satoshi\|Yamanaka, Takeharu\|Tsuchihara, Katsuya\|Ohtsu, Atsushi
PMID:	24006859

58.
Journal:	N Engl J Med. 2013 Sep 12;369(11):1023-34.
Title:	Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.
Author:	Douillard, Jean-Yves\|Oliner, Kelly S\|Siena, Salvatore\|Tabernero, Josep\|Burkes, Ronald\|Barugel, Mario\|Humblet, Yves\|Bodoky, Gyorgy\|Cunningham, David\|Jassem, Jacek\|Rivera, Fernando\|Kocakova, Ilona\|Ruff, Paul\|Blasinska-Morawiec, Maria\|Smakal, Martin\|Canon, J
PMID:	24024839

59.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1098-103.
Title:	Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy.
Author:	Pietrantonio, Filippo\|Perrone, Federica\|Biondani, Pamela\|Maggi, Claudia\|Lampis, Andrea\|Bertan, Claudia\|Venturini, Filippo\|Tondulli, Luca\|Ferrari, Daris\|Ricci, Vincenzo\|Villa, Federica\|Barone, Gloria\|Bianco, Nadia\|Ghidini, Antonio\|Bossi, Ilaria\|Fanetti, Gi
PMID:	24025413

60.
Journal:	Am J Gastroenterol. 2013 Nov;108(11):1785-93.
Title:	Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Author:	Mouradov, Dmitri\|Domingo, Enric\|Gibbs, Peter\|Jorissen, Robert N\|Li, Shan\|Soo, Pik Ying\|Lipton, Lara\|Desai, Jayesh\|Danielsen, Havard E\|Oukrif, Dahmane\|Novelli, Marco\|Yau, Christopher\|Holmes, Christopher C\|Jones, Ian T\|McLaughlin, Stephen\|Molloy, Peter\|Hawk
PMID:	24042191

61.
Journal:	Cancer Med. 2013 Aug;2(4):496-506.
Title:	PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival.
Author:	Atreya, Chloe E\|Sangale, Zaina\|Xu, Nafei\|Matli, Mary R\|Tikishvili, Eliso\|Welbourn, William\|Stone, Steven\|Shokat, Kevan M\|Warren, Robert S
PMID:	24156022

62.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title:	Multigene assays in metastatic colorectal cancer.
Author:	Deeb, Kristin K\|Sram, Jakub P\|Gao, Hanlin\|Fakih, Marwan G
PMID:	24158971

63.
Journal:	J Clin Oncol. 2013 Dec 20;31(36):4562-8.
Title:	Evaluating many treatments and biomarkers in oncology: a new design.
Author:	Kaplan, Richard\|Maughan, Timothy\|Crook, Angela\|Fisher, David\|Wilson, Richard\|Brown, Louise\|Parmar, Mahesh
PMID:	24248692

64.
Journal:	Cancer Manag Res. 2013 Nov 21;5:387-400.
Title:	Personalized treatment for advanced colorectal cancer: KRAS and beyond.
Author:	Patel, Gargi Surendra\|Karapetis, Christos S
PMID:	24294007

65.
Journal:	PLoS One. 2013 Dec 10;8(12):e81628.
Title:	Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.
Author:	Shen, Yinchen\|Wang, Jianfei\|Han, Xiaohong\|Yang, Hongying\|Wang, Shuai\|Lin, Dongmei\|Shi, Yuankai
PMID:	24339949

66.
Journal:	J Gastrointest Cancer. 2014 Mar;45(1):34-9.
Title:	Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer.
Author:	Russo, Andrea L\|Ryan, David P\|Borger, Darrell R\|Wo, Jennifer Y\|Szymonifka, Jackie\|Liang, Wen-Yih\|Kwak, Eunice L\|Blaszkowsky, Lawrence S\|Clark, Jeffrey W\|Allen, Jill N\|Zhu, Andrew X\|Berger, David L\|Cusack, James C\|Mamon, Harvey J\|Haigis, Kevin M\|Hong, Theo
PMID:	24006244

67.
Journal:	Pharmacol Ther. 2014 May;142(2):176-82.
Title:	BRAF inhibitors in cancer therapy.
Author:	Hertzman Johansson, Carolina\|Egyhazi Brage, Suzanne
PMID:	24325952

68.
Journal:	Ann Oncol. 2014 Feb;25(2):404-8.
Title:	Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.
Author:	Pietrantonio, F\|Perrone, F\|de Braud, F\|Castano, A\|Maggi, C\|Bossi, I\|Gevorgyan, A\|Biondani, P\|Pacifici, M\|Busico, A\|Gariboldi, M\|Festinese, F\|Tamborini, E\|Di Bartolomeo, M
PMID:	24379162

69.
Journal:	Gan To Kagaku Ryoho. 2014 Jan;41(1):1-6.
Title:	[Clinical application of next-generation sequencing technologies to achieve cancer precision medicine].
Author:	Tsuchihara, Katsuya
PMID:	24423944

70.
Journal:	Digestion. 2014;89(1):18-23.
Title:	Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author:	Okada, Yasuyuki\|Miyamoto, Hiroshi\|Goji, Takahiro\|Takayama, Tetsuji
PMID:	24458108

71.
Journal:	Cancer. 2014 May 15;120(10):1482-90.
Title:	Mutational analysis and clinical correlation of metastatic colorectal cancer.
Author:	Russo, Andrea L\|Borger, Darrell R\|Szymonifka, Jackie\|Ryan, David P\|Wo, Jennifer Y\|Blaszkowsky, Lawrence S\|Kwak, Eunice L\|Allen, Jill N\|Wadlow, Raymond C\|Zhu, Andrew X\|Murphy, Janet E\|Faris, Jason E\|Dias-Santagata, Dora\|Haigis, Kevin M\|Ellisen, Leif W\|Iafr
PMID:	24500602

72.
Journal:	Sci Transl Med. 2014 Feb 19;6(224):224ra26.
Title:	Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
Author:	Misale, Sandra\|Arena, Sabrina\|Lamba, Simona\|Siravegna, Giulia\|Lallo, Alice\|Hobor, Sebastijan\|Russo, Mariangela\|Buscarino, Michela\|Lazzari, Luca\|Sartore-Bianchi, Andrea\|Bencardino, Katia\|Amatu, Alessio\|Lauricella, Calogero\|Valtorta, Emanuele\|Siena, Salvato
PMID:	24553387

73.
Journal:	Eur J Cancer. 2014 May;50(8):1430-6.
Title:	RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
Author:	Sclafani, F\|Gonzalez, D\|Cunningham, D\|Hulkki Wilson, S\|Peckitt, C\|Giralt, J\|Glimelius, B\|Rosello Keranen, S\|Wotherspoon, A\|Brown, G\|Tait, D\|Oates, J\|Chau, I
PMID:	24582914

74.
Journal:	Nihon Rinsho. 2014 Jan;72(1):29-34.
Title:	[Perspective of personalized (precise) cancer therapy based on predictive biomarkers].
Author:	Osera, Shozo\|Yoshino, Takayuki
PMID:	24597345

75.
Journal:	BMC Genomics. 2014 Mar 13;15:190.
Title:	Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author:	Castle, John C\|Loewer, Martin\|Boegel, Sebastian\|de Graaf, Jos\|Bender, Christian\|Tadmor, Arbel D\|Boisguerin, Valesca\|Bukur, Thomas\|Sorn, Patrick\|Paret, Claudia\|Diken, Mustafa\|Kreiter, Sebastian\|Tureci, Ozlem\|Sahin, Ugur
PMID:	24621249

76.
Journal:	PLoS One. 2014 Apr 1;9(4):e92147.
Title:	Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status.
Author:	Pietrantonio, Filippo\|Maggi, Claudia\|Di Bartolomeo, Maria\|Facciorusso, Maria Grazia\|Perrone, Federica\|Testi, Adele\|Iacovelli, Roberto\|Miceli, Rosalba\|Bossi, Ilaria\|Leone, Giorgia\|Milione, Massimo\|Pelosi, Giuseppe\|de Braud, Filippo
PMID:	24691006

77.
Journal:	Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title:	The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author:	Abdul-Jalil, Khairun I\|Sheehan, Katherine M\|Toomey, Sinead\|Schmid, Jasmin\|Prehn, Jochen\|O'Grady, Anthony\|Cummins, Robert\|O'Neill, Brian\|McNamara, Deborah A\|Deasy, Joseph\|Breathnach, Oscar\|Grogan, Liam\|Rogers, Ailin\|Doherty, Glen\|Winter, Des\|Ryan, John\|El-
PMID:	24700299

78.
Journal:	Lancet Oncol. 2014 May;15(6):631-9.
Title:	Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.
Author:	Wasan, Harpreet\|Meade, Angela M\|Adams, Richard\|Wilson, Richard\|Pugh, Cheryl\|Fisher, David\|Sydes, Benjamin\|Madi, Ayman\|Sizer, Bruce\|Lowdell, Charles\|Middleton, Gary\|Butler, Rachel\|Kaplan, Richard\|Maughan, Tim
PMID:	24703531

79.
Journal:	Dig Dis Sci. 2014 Sep;59(9):2255-63.
Title:	Genetic mechanisms in interval colon cancers.
Author:	Richter, James M\|Pino, Maria Simona\|Austin, Thomas R\|Campbell, Emily\|Szymonifka, Jackie\|Russo, Andrea L\|Hong, Theodore S\|Borger, Darrell\|Iafrate, A John\|Chung, Daniel C
PMID:	24705641

80.
Journal:	Rev Recent Clin Trials. 2014;9(1):8-12.
Title:	The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies.
Author:	Meriggi, Fausto\|Vermi, William\|Bertocchi, Paola\|Zaniboni, Alberto
PMID:	24758538

81.
Journal:	Future Oncol. 2014 Apr;10(5):713-23.
Title:	Pyrosequencing evaluation of low-frequency KRAS mutant alleles for EGF receptor therapy selection in metastatic colorectal carcinoma.
Author:	Natalicchio, Maria Iole\|Improta, Giuseppina\|Zupa, Angela\|Cursio, Olga Elisabetta\|Stampone, Emanuela\|Possidente, Luciana\|Teresa Gerardi, Assunta Maria\|Vita, Giulia\|Martini, Maurizio\|Cassano, Alessandra\|Piccoli, Claudia\|Romito, Sante\|Aieta, Michele\|Antonett
PMID:	24799053

82.
Journal:	Oncol Rep. 2014 Jul;32(1):50-6.
Title:	Clinicopathological characteristics and prognostic impact of colorectal cancers with NRAS mutations.
Author:	Ogura, Toshiro\|Kakuta, Miho\|Yatsuoka, Toshimasa\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Yamaguchi, Kensei\|Tanabe, Minoru\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	24806883

83.
Journal:	Am J Surg Pathol. 2014 Sep;38(9):1235-41.
Title:	Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach.
Author:	Lasota, Jerzy\|Kowalik, Artur\|Wasag, Bartosz\|Wang, Zeng-Feng\|Felisiak-Golabek, Anna\|Coates, Tiffany\|Kopczynski, Janusz\|Gozdz, Stanislaw\|Miettinen, Markku
PMID:	24832158

84.
Journal:	Am Soc Clin Oncol Educ Book. 2014:91-9.
Title:	The evolution of our molecular understanding of colorectal cancer: what we are doing now, what the future holds, and how tumor profiling is just the beginning.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	24857065

85.
Journal:	BMJ Open. 2014 May 23;4(5):e004652.
Title:	KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: a cohort study.
Author:	Negru, Serban\|Papadopoulou, Eirini\|Apessos, Angela\|Stanculeanu, Dana Lucia\|Ciuleanu, Eliade\|Volovat, Constantin\|Croitoru, Adina\|Kakolyris, Stylianos\|Aravantinos, Gerasimos\|Ziras, Nikolaos\|Athanasiadis, Elias\|Touroutoglou, Nikolaos\|Pavlidis, Nikolaos\|Kalof
PMID:	24859998

86.
Journal:	Ann Oncol. 2014 Sep;25(9):1756-61.
Title:	Clinical activity of FOLFIRI plus cetuximab according to extended gene mutation status by next-generation sequencing: findings from the CAPRI-GOIM trial.
Author:	Ciardiello, F\|Normanno, N\|Maiello, E\|Martinelli, E\|Troiani, T\|Pisconti, S\|Giuliani, F\|Barone, C\|Carteni, G\|Rachiglio, A M\|Montesarchio, V\|Tonini, G\|Rizzi, D\|Cinieri, S\|Bordonaro, R\|Febbraro, A\|De Vita, F\|Orditura, M\|Fenizia, F\|Lambiase, M\|Rinaldi, A\|Tatan
PMID:	24942275

87.
Journal:	Clin Cancer Res. 2014 Aug 15;20(16):4251-61.
Title:	Phase I expansion and pharmacodynamic study of the oral MEK inhibitor RO4987655 (CH4987655) in selected patients with advanced cancer with RAS-RAF mutations.
Author:	Zimmer, Lisa\|Barlesi, Fabrice\|Martinez-Garcia, Maria\|Dieras, Veronique\|Schellens, Jan H M\|Spano, Jean-Philippe\|Middleton, Mark R\|Calvo, Emiliano\|Paz-Ares, Luiz\|Larkin, James\|Pacey, Simon\|Venturi, Miro\|Kraeber-Bodere, Francoise\|Tessier, Jean J L\|Eberhardt,
PMID:	24947927

88.
Journal:	J Clin Pathol. 2014 Sep;67(9):751-7.
Title:	RAS testing of colorectal carcinoma-a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group.
Author:	Wong, Newton A C S\|Gonzalez, David\|Salto-Tellez, Manuel\|Butler, Rachel\|Diaz-Cano, Salvador J\|Ilyas, Mohammad\|Newman, William\|Shaw, Emily\|Taniere, Philippe\|Walsh, Shaun V
PMID:	24996433

89.
Journal:	Ann Oncol. 2014 Oct;25(10):2008-14.
Title:	Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer.
Author:	Morris, V K\|Lucas, F A San\|Overman, M J\|Eng, C\|Morelli, M P\|Jiang, Z-Q\|Luthra, R\|Meric-Bernstam, F\|Maru, D\|Scheet, P\|Kopetz, S\|Vilar, E
PMID:	25009008

90.
Journal:	Biomed Res Int. 2014;2014:591867.
Title:	Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	25032217

91.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):9732-43.
Title:	Beyond KRAS: Predictive factors of the efficacy of anti-EGFR monoclonal antibodies in the treatment of metastatic colorectal cancer.
Author:	De Stefano, Alfonso\|Carlomagno, Chiara
PMID:	25110411

92.
Journal:	Genome Biol. 2014 Aug 28;15(8):454.
Title:	Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Author:	Brannon, A Rose\|Vakiani, Efsevia\|Sylvester, Brooke E\|Scott, Sasinya N\|McDermott, Gregory\|Shah, Ronak H\|Kania, Krishan\|Viale, Agnes\|Oschwald, Dayna M\|Vacic, Vladimir\|Emde, Anne-Katrin\|Cercek, Andrea\|Yaeger, Rona\|Kemeny, Nancy E\|Saltz, Leonard B\|Shia, Jinru
PMID:	25164765

93.
Journal:	Neoplasia. 2014 Sep;16(9):751-6.
Title:	Optimizing single agent panitumumab therapy in pre-treated advanced colorectal cancer.
Author:	Gasparini, Giampietro\|Buttitta, Fiamma\|D'Andrea, Mario Rosario\|Tumolo, Salvatore\|Buonadonna, Angela\|Pavese, Ida\|Cordio, Stefano\|De Tursi, Michele\|Mosconi, Stefania\|Stumbo, Luciano\|Felicioni, Lara\|Marchetti, Antonio
PMID:	25246275

94.
Journal:	Clin Biochem. 2014 Dec;47(18):340-3.
Title:	High-throughput screening of extended RAS mutations based on high-resolution melting analysis for prediction of anti-EGFR treatment efficacy in colorectal carcinoma.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Sato, Kenichi\|Kitamura, Kouichi\|Nishimura, Motoi\|Sawai, Setsu\|Matsushita, Kazuyuki\|Suzuki, Kazufumi\|Ota, Satoshi\|Miyauchi, Hideaki\|Matsubara, Hisahiro\|Nakatani, Yukio\|Nomura, Fumio
PMID:	25262986

95.
Journal:	Oncotarget. 2014 Sep 15;5(17):7936-44.
Title:	Mutant NRASQ61 shares signaling similarities across various cancer types--potential implications for future therapies.
Author:	Vujic, Igor\|Posch, Christian\|Sanlorenzo, Martina\|Yen, Adam J\|Tsumura, Aaron\|Kwong, Andrew\|Feichtenschlager, Valentin\|Lai, Kevin\|Arneson, Douglas V\|Rappersberger, Klemens\|Ortiz-Urda, Susana M
PMID:	25277205

96.
Journal:	Cancer Discov. 2014 Nov;4(11):1269-80.
Title:	Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution.
Author:	Misale, Sandra\|Di Nicolantonio, Federica\|Sartore-Bianchi, Andrea\|Siena, Salvatore\|Bardelli, Alberto
PMID:	25293556

97.
Journal:	Onco Targets Ther. 2014 Oct 4;7:1817-28.
Title:	Colorectal cancer in Chinese patients: current and emerging treatment options.
Author:	Li, Leung\|Ma, Brigette By
PMID:	25336973

98.
Journal:	Int J Clin Exp Pathol. 2014 Aug 15;7(9):5927-39. eCollection 2014.
Title:	Comparison of neuroendocrine differentiation and KRAS/NRAS/BRAF/PIK3CA/TP53 mutation status in primary and metastatic colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Novy, Michael\|Oberkanins, Christian\|Xu, Li\|Li, Guojun\|Loland, Christiane\|Poetsch, Micaela
PMID:	25337237

99.
Journal:	Drugs Today (Barc). 2014 Oct;50(10):679-90.
Title:	Panitumumab in the treatment of colon cancer: A biomarker dilemma.
Author:	Scott, A\|Messersmith, W A\|Jimeno, A\|Davies, S L
PMID:	25374966

100.
Journal:	Oncol Res Treat. 2014;37(11):646-52.
Title:	Efficacy of triplet combination chemotherapy with oxaliplatin, irinotecan and capecitabine (OCX) in metastatic colorectal cancer in relation to RAS/RAF mutation status: results of a retrospective analysis.
Author:	Brunner, Stefan\|von Moos, Roger\|Mey, Ulrich\|Camenisch Gross, Ulrike\|Freyholdt, Tobias\|Cathomas, Richard
PMID:	25427581

101.
Journal:	F1000Prime Rep. 2014 Nov 4;6:108.
Title:	Management of colorectal cancer.
Author:	Stintzing, Sebastian
PMID:	25580262

102.
Journal:	Pol J Pathol. 2014 Dec;65(4):257-66.
Title:	Molecular pathology of colorectal cancer.
Author:	Bosman, Ft\|Yan, P
PMID:	25693079

103.
Journal:	Gastrointest Tumors. 2014 May;1(4):209-20.
Title:	Colorectal Cancer: Personalized Therapy.
Author:	Leichsenring, Jona\|Koppelle, Adrian\|Reinacher-Schick, Ank
PMID:	26676107

104.
Journal:	Indian J Cancer. 2014 Oct-Dec;51(4):531-7.
Title:	Prevalence of KRAS mutations in metastatic colorectal cancer: A retrospective observational study from India.
Author:	Veldore, V H\|Rao, M R\|Prabhudesai, S A\|Tejaswi, R\|Kakara, S\|Pattanayak, S\|Krishnamoorthy, N\|Tejaswini, B N\|Hazarika, D\|Gangoli, A\|Rahman, S M\|Dixit, J\|Naik, R\|Diwakar, R B\|Satheesh, C T\|Shashidhara, H P\|Patil, S\|Gopinath, K S\|Kumar, B S
PMID:	26842186

105.
Journal:	Leukemia. 2015 Jan;29(1):27-37.
Title:	Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Author:	Weisberg, Ellen\|Nonami, Atsushi\|Chen, Zhao\|Liu, Feiyang\|Zhang, Jianming\|Sattler, Martin\|Nelson, Erik\|Cowens, Kristen\|Christie, Amanda L\|Mitsiades, Constantine\|Wong, Kwok-Kin\|Liu, Qingsong\|Gray, Nathanael\|Griffin, James D
PMID:	24791855

106.
Journal:	Int J Cancer. 2015 Jan 1;136(1):83-90.
Title:	Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.
Author:	Schirripa, Marta\|Cremolini, Chiara\|Loupakis, Fotios\|Morvillo, Manfredi\|Bergamo, Francesca\|Zoratto, Federica\|Salvatore, Lisa\|Antoniotti, Carlotta\|Marmorino, Federica\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|De Gregorio, Veronica\|Giannini, Riccardo
PMID:	24806288

107.
Journal:	Clin Cancer Res. 2015 Mar 1;21(5):1087-97.
Title:	Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy.
Author:	Laurent-Puig, Pierre\|Pekin, Deniz\|Normand, Corinne\|Kotsopoulos, Steve K\|Nizard, Philippe\|Perez-Toralla, Karla\|Rowell, Rachel\|Olson, Jeff\|Srinivasan, Preethi\|Le Corre, Delphine\|Hor, Thevy\|El Harrak, Zakaria\|Li, Xinyu\|Link, Darren R\|Bouche, Olivier\|Emile, J
PMID:	25248381

108.
Journal:	Virchows Arch. 2015 Jan;466(1):13-20.
Title:	Medullary carcinoma of the colon: can the undifferentiated be differentiated?
Author:	Fiehn, Anne-Marie Kanstrup\|Grauslund, Morten\|Glenthoj, Anders\|Melchior, Linea Cecilie\|Vainer, Ben\|Willemoe, Gro Linno
PMID:	25339302

109.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):264-73.
Title:	Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.
Author:	Garcia-Alfonso, P\|Garcia-Foncillas, J\|Salazar, R\|Perez-Segura, P\|Garcia-Carbonero, R\|Musulen-Palet, E\|Cuatrecasas, M\|Landolfi, S\|Ramon Y Cajal, S\|Navarro, S
PMID:	25373533

110.
Journal:	J Clin Pathol. 2015 Jan;68(1):64-8.
Title:	Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients.
Author:	Malapelle, Umberto\|Vigliar, Elena\|Sgariglia, Roberta\|Bellevicine, Claudio\|Colarossi, Lorenzo\|Vitale, Domenico\|Pallante, Pierlorenzo\|Troncone, Giancarlo
PMID:	25378536

111.
Journal:	Target Oncol. 2015 Sep;10(3):415-21.
Title:	Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?
Author:	Allard, M A\|Saffroy, R\|de la Maisonneuve, P Bouvet\|Ricca, L\|Bosselut, N\|Hamelin, J\|Lecorche, E\|Bejarano, M A\|Innominato, P\|Sebagh, M\|Adam, R\|Morere, J F\|Lemoine, A
PMID:	25420993

112.
Journal:	Ann Surg Oncol. 2015 Aug;22(8):2640-8.
Title:	Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.
Author:	Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Mitsuhashi, Kei\|Ito, Miki\|Okuda, Hiroyuki\|Kanno, Shinichi\|Naito, Takafumi\|Yoshii, Shinji\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Adachi, Yasushi\|Okita, Kenji\|Hirata, Koichi\|Imamura, Yu\|B
PMID:	25472647

113.
Journal:	Cancer. 2015 Apr 15;121(8):1195-203.
Title:	RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer.
Author:	Yaeger, Rona\|Cowell, Elizabeth\|Chou, Joanne F\|Gewirtz, Alexandra N\|Borsu, Laetitia\|Vakiani, Efsevia\|Solit, David B\|Rosen, Neal\|Capanu, Marinela\|Ladanyi, Marc\|Kemeny, Nancy
PMID:	25491172

114.
Journal:	J Clin Oncol. 2015 Mar 1;33(7):692-700.
Title:	Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer.
Author:	Van Cutsem, Eric\|Lenz, Heinz-Josef\|Kohne, Claus-Henning\|Heinemann, Volker\|Tejpar, Sabine\|Melezinek, Ivan\|Beier, Frank\|Stroh, Christopher\|Rougier, Philippe\|van Krieken, J Han\|Ciardiello, Fortunato
PMID:	25605843

115.
Journal:	Clin Cancer Res. 2015 May 1;21(9):2157-66.
Title:	Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
Author:	Arena, Sabrina\|Bellosillo, Beatriz\|Siravegna, Giulia\|Martinez, Alejandro\|Canadas, Israel\|Lazzari, Luca\|Ferruz, Noelia\|Russo, Mariangela\|Misale, Sandra\|Gonzalez, Iria\|Iglesias, Mar\|Gavilan, Elena\|Corti, Giorgio\|Hobor, Sebastijan\|Crisafulli, Giovanni\|Salido
PMID:	25623215

116.
Journal:	Biochem Biophys Res Commun. 2015 Feb 27;458(1):52-6.
Title:	Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.
Author:	Kogita, Akihiro\|Yoshioka, Yasumasa\|Sakai, Kazuko\|Togashi, Yosuke\|Sogabe, Shunsuke\|Nakai, Takuya\|Okuno, Kiyotaka\|Nishio, Kazuto
PMID:	25623536

117.
Journal:	Oncologist. 2015 Mar;20(3):257-62.
Title:	External quality assessment unravels interlaboratory differences in quality of RAS testing for anti-EGFR therapy in colorectal cancer.
Author:	Tack, Veronique\|Ligtenberg, Marjolijn J L\|Tembuyser, Lien\|Normanno, Nicola\|Vander Borght, Sara\|Han van Krieken, J\|Dequeker, Elisabeth M C
PMID:	25657200

118.
Journal:	Curr Gastroenterol Rep. 2015 Feb;17(2):431.
Title:	Molecular markers predictive of chemotherapy response in colorectal cancer.
Author:	Shiovitz, Stacey\|Grady, William M
PMID:	25663616

119.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):91-8.
Title:	FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Author:	Kaczirek, Klaus\|Ciuleanu, Tudor E\|Vrbanec, Damir\|Marton, Erika\|Messinger, Diethelm\|Liegl-Atzwanger, Bernadette\|Wrba, Fritz\|Knittelfelder, Regina\|Lindner, Elisabeth\|Zielinski, Christoph C\|Streubel, Berthold\|Brodowicz, Thomas
PMID:	25666295

120.
Journal:	Hum Pathol. 2015 Apr;46(4):507-13.
Title:	Novel molecular insights from routine genotyping of colorectal carcinomas.
Author:	Stachler, Matthew D\|Rinehart, Elizabeth\|Lindeman, Neal\|Odze, Robert\|Srivastava, Amitabh
PMID:	25683705

121.
Journal:	Br J Cancer. 2015 Mar 17;112(6):1088-97.
Title:	Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.
Author:	Chen, Z-Y\|Raghav, K\|Lieu, C H\|Jiang, Z-Q\|Eng, C\|Vauthey, J-N\|Chang, G J\|Qiao, W\|Morris, J\|Hong, D\|Hoff, P\|Tran, H\|Menter, D G\|Heymach, J\|Overman, M\|Kopetz, S
PMID:	25688736

122.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

123.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

124.
Journal:	Br J Cancer. 2015 Mar 17;112(6):963-70.
Title:	Correlation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancer.
Author:	Price, T J\|Bruhn, M A\|Lee, C K\|Hardingham, J E\|Townsend, A R\|Mann, K P\|Simes, J\|Weickhardt, A\|Wrin, J W\|Wilson, K\|Gebski, V\|Van Hazel, G\|Robinson, B\|Cunningham, D\|Tebbutt, N C
PMID:	25742472

125.
Journal:	Oncotarget. 2015 Mar 30;6(9):7209-20.
Title:	Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.
Author:	Mitsuhashi, Kei\|Nosho, Katsuhiko\|Sukawa, Yasutaka\|Matsunaga, Yasutaka\|Ito, Miki\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Naito, Takafumi\|Adachi, Yasushi\|Tachibana, Mami\|Tanuma, Tokuma\|Maguchi, Hiroyuki\|Shinohara, Toshiya\|Hasegawa, Tadashi\|I
PMID:	25797243

126.
Journal:	Cancer Sci. 2015 Mar;106(3):324-7.
Title:	Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients.
Author:	Taniguchi, Hiroya\|Yamazaki, Kentaro\|Yoshino, Takayuki\|Muro, Kei\|Yatabe, Yasushi\|Watanabe, Toshiaki\|Ebi, Hiromichi\|Ochiai, Atsushi\|Baba, Eishi\|Tsuchihara, Katsuya
PMID:	25800101

127.
Journal:	Biomark Med. 2015;9(4):337-47.
Title:	Personalized treatment for patients with colorectal cancer: role of biomarkers.
Author:	Duffy, Michael J
PMID:	25808438

128.
Journal:	Ann Oncol. 2015 Aug;26(8):1710-4.
Title:	Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial.
Author:	Normanno, N\|Rachiglio, A M\|Lambiase, M\|Martinelli, E\|Fenizia, F\|Esposito, C\|Roma, C\|Troiani, T\|Rizzi, D\|Tatangelo, F\|Botti, G\|Maiello, E\|Colucci, G\|Ciardiello, F
PMID:	25851630

129.
Journal:	Oncoscience. 2015 Feb 9;2(2):125-30.
Title:	RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions.
Author:	de Macedo, Mariana Petaccia\|de Melo, Fernanda Machado\|Ribeiro, Julia da Silva\|de Mello, Celso Abdon Lopes\|de Souza Begnami, Maria Dirlei Ferreira\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|da Cunha, Isabela Werneck
PMID:	25859555

130.
Journal:	J Surg Oncol. 2015 Jun;111(7):905-10.
Title:	Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers.
Author:	Lan, Yuan-Tzu\|Jen-Kou, Lin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Lin, Chun-Chi\|Wang, Huann-Sheng\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Jiang, Jeng-Kai\|Chang, Shih-Ching
PMID:	25920435

131.
Journal:	J Clin Pathol. 2015 Aug;68(8):657-60.
Title:	Are all RAS mutations the same? Coexisting KRAS and NRAS mutations in a caecal adenocarcinoma and contiguous tubulovillous adenoma.
Author:	Vagaja, N N\|Parry, J\|McCallum, D\|Thomas, M A\|Bentel, J M
PMID:	25926041

132.
Journal:	Eur J Cancer. 2015 Jul;51(10):1243-52.
Title:	FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer.
Author:	Bokemeyer, C\|Kohne, C-H\|Ciardiello, F\|Lenz, H-J\|Heinemann, V\|Klinkhardt, U\|Beier, F\|Duecker, K\|van Krieken, J H\|Tejpar, S
PMID:	25937522

133.
Journal:	Oncotarget. 2015 Jun 20;6(17):15681-9.
Title:	RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.
Author:	Boleij, Annemarie\|Tops, Bastiaan B J\|Rombout, Paul D M\|Dequeker, Elizabeth M\|Ligtenberg, Marjolijn J L\|van Krieken, J Han
PMID:	25944693

134.
Journal:	PLoS One. 2015 May 8;10(5):e0121891.
Title:	Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.
Author:	Sakai, Kazuko\|Tsurutani, Junji\|Yamanaka, Takeharu\|Yoneshige, Azusa\|Ito, Akihiko\|Togashi, Yosuke\|De Velasco, Marco A\|Terashima, Masato\|Fujita, Yoshihiko\|Tomida, Shuta\|Tamura, Takao\|Nakagawa, Kazuhiko\|Nishio, Kazuto
PMID:	25954997

135.
Journal:	Am J Clin Pathol. 2015 Jun;143(6):879-88.
Title:	Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer.
Author:	Gleeson, Ferga C\|Kipp, Benjamin R\|Voss, Jesse S\|Campion, Michael B\|Minot, Douglas M\|Tu, Zheng J\|Klee, Eric W\|Sciallis, Andrew P\|Graham, Rondell P\|Lazaridis, Konstantinos N\|Henry, Michael R\|Levy, Michael J
PMID:	25972331

136.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):254-7.
Title:	[Detection of KRAS,NRAS and BRAF gene mutations in colorectal carcinoma].
Author:	Zhang, Keping\|Xu, Jie\|Yan, Lixu\|Liu, Xunhua\|Xu, Fangping\|Liu, Yanhui
PMID:	25975908

137.
Journal:	Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title:	Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25993166

138.
Journal:	Clin Transl Oncol. 2015 Sep;17(9):751-6.
Title:	RAS status in Korean patients with stage III and IV colorectal cancer.
Author:	Lee, W-S\|Lee, J N\|Baek, J-H\|Park, Y H
PMID:	25997687

139.
Journal:	J Gastrointest Oncol. 2015 Jun;6(3):314-21.
Title:	Extended RAS testing in metastatic colorectal cancer-Refining the predictive molecular biomarkers.
Author:	Al-Shamsi, Humaid O\|Alhazzani, Waleed\|Wolff, Robert A
PMID:	26029459

140.
Journal:	Nat Med. 2015 Jul;21(7):795-801.
Title:	Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Author:	Siravegna, Giulia\|Mussolin, Benedetta\|Buscarino, Michela\|Corti, Giorgio\|Cassingena, Andrea\|Crisafulli, Giovanni\|Ponzetti, Agostino\|Cremolini, Chiara\|Amatu, Alessio\|Lauricella, Calogero\|Lamba, Simona\|Hobor, Sebastijan\|Avallone, Antonio\|Valtorta, Emanuele\|R
PMID:	26030179

141.
Journal:	World J Gastroenterol. 2015 Jun 7;21(21):6470-8.
Title:	Different treatment strategies and molecular features between right-sided and left-sided colon cancers.
Author:	Shen, Hong\|Yang, Jiao\|Huang, Qing\|Jiang, Meng-Jie\|Tan, Yi-Nuo\|Fu, Jian-Fei\|Zhu, Li-Zhen\|Fang, Xue-Feng\|Yuan, Ying
PMID:	26074686

142.
Journal:	Clin Colorectal Cancer. 2015 Dec;14(4):203-18.
Title:	Current and Future Approaches to Target the Epidermal Growth Factor Receptor and Its Downstream Signaling in Metastatic Colorectal Cancer.
Author:	Lee, Michael S\|Kopetz, Scott
PMID:	26077270

143.
Journal:	Oncotarget. 2015 Oct 6;6(30):28929-37.
Title:	Identification and characterization of RET fusions in advanced colorectal cancer.
Author:	Le Rolle, Anne-France\|Klempner, Samuel J\|Garrett, Christopher R\|Seery, Tara\|Sanford, Eric M\|Balasubramanian, Sohail\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Chiu, Vi K
PMID:	26078337

144.
Journal:	EBioMedicine. 2015 Feb 14;2(4):317-23.
Title:	Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.
Author:	Yoshino, Takayuki\|Muro, Kei\|Yamaguchi, Kensei\|Nishina, Tomohiro\|Denda, Tadamichi\|Kudo, Toshihiro\|Okamoto, Wataru\|Taniguchi, Hiroya\|Akagi, Kiwamu\|Kajiwara, Takeshi\|Hironaka, Shuichi\|Satoh, Taroh
PMID:	26137573

145.
Journal:	Exp Mol Pathol. 2015 Oct;99(2):207-11.
Title:	Development of pyrosequencing methods for the rapid detection of RAS mutations in clinical samples.
Author:	Cortes, Ulrich\|Guilloteau, Karline\|Rouvreau, Melanie\|Archaimbault, Celine\|Villalva, Claire\|Karayan-Tapon, Lucie
PMID:	26163758

146.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1416-8.
Title:	Real-Life Distribution of KRAS and NRAS Mutations in Metastatic Colorectal Carcinoma from French Routine Genotyping.
Author:	Piton, Nicolas\|Lonchamp, Etienne\|Nowak, Frederique\|Sabourin, Jean-Christophe
PMID:	26189770

147.
Journal:	Diagn Pathol. 2015 Jul 30;10:132.
Title:	Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.
Author:	Kriegsmann, Mark\|Arens, Norbert\|Endris, Volker\|Weichert, Wilko\|Kriegsmann, Jorg
PMID:	26220423

148.
Journal:	Mod Pathol. 2015 Oct;28(10):1390-9.
Title:	Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers.
Author:	Haley, Lisa\|Tseng, Li-Hui\|Zheng, Gang\|Dudley, Jonathan\|Anderson, Derek A\|Azad, Nilofer S\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26226847

149.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

150.
Journal:	BMC Cancer. 2015 Aug 1;15:567.
Title:	Durable recurrence-free survival after pneumonectomy for late lung metastasis from rectal cancer: case report with genetic and epigenetic analyses.
Author:	Imperatori, Andrea\|Rotolo, Nicola\|Dominioni, Lorenzo\|Nardecchia, Elisa\|Cattoni, Maria\|Cimetti, Laura\|Riva, Cristina\|Sessa, Fausto\|Furlan, Daniela
PMID:	26231173

151.
Journal:	J Clin Pathol. 2015 Dec;68(12):1044.
Title:	Coexisting KRAS and NRAS mutations in colon cancer.
Author:	Sorscher, Steven
PMID:	26243064

152.
Journal:	Cancer Discov. 2015 Aug;5(8):832-41.
Title:	HER2 activating mutations are targets for colorectal cancer treatment.
Author:	Kavuri, Shyam M\|Jain, Naveen\|Galimi, Francesco\|Cottino, Francesca\|Leto, Simonetta M\|Migliardi, Giorgia\|Searleman, Adam C\|Shen, Wei\|Monsey, John\|Trusolino, Livio\|Jacobs, Samuel A\|Bertotti, Andrea\|Bose, Ron
PMID:	26243863

153.
Journal:	J Mol Diagn. 2015 Nov;17(6):705-14.
Title:	MSIplus for Integrated Colorectal Cancer Molecular Testing by Next-Generation Sequencing.
Author:	Hempelmann, Jennifer A\|Scroggins, Sheena M\|Pritchard, Colin C\|Salipante, Stephen J
PMID:	26322950

154.
Journal:	Br J Cancer. 2015 Sep 15;113(6):914-20.
Title:	KRAS, NRAS, BRAF mutation comparison of endoscopic and surgically removed primary CRC paired samples: is endoscopy biopsy material adequate for molecular evaluation?
Author:	Saridaki, Z\|Saegart, X\|De Vriendt, V\|Hatzidaki, D\|Palmans, S\|De Smedt, L\|De Hertogh, G\|Tejpar, S
PMID:	26325103

155.
Journal:	Ther Adv Med Oncol. 2015 Sep;7(5):252-62.
Title:	Precision medicine in colorectal cancer: the molecular profile alters treatment strategies.
Author:	Tran, Nguyen H\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Clipson, Linda\|Matkowskyj, Kristina A\|Deming, Dustin A
PMID:	26327923

156.
Journal:	J Transl Med. 2015 Sep 3;13:287.
Title:	The Italian external quality assessment for RAS testing in colorectal carcinoma identifies methods-related inter-laboratory differences.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Fenizia, Francesca\|Barberis, Massimo\|Marchetti, Antonio\|Fontanini, Gabriella\|De Rosa, Gaetano\|Taddei, Gian Luigi
PMID:	26335936

157.
Journal:	Cell. 2015 Sep 10;162(6):1257-70.
Title:	Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.
Author:	Zelenay, Santiago\|van der Veen, Annemarthe G\|Bottcher, Jan P\|Snelgrove, Kathryn J\|Rogers, Neil\|Acton, Sophie E\|Chakravarty, Probir\|Girotti, Maria Romina\|Marais, Richard\|Quezada, Sergio A\|Sahai, Erik\|Reis e Sousa, Caetano
PMID:	26343581

158.
Journal:	Pathology. 2015 Oct;47(6):551-6.
Title:	KRAS, NRAS, BRAF mutations and high counts of poorly differentiated clusters of neoplastic cells in colorectal cancer: observational analysis of 175 cases.
Author:	Barresi, Valeria\|Bonetti, Luca Reggiani\|Bettelli, Stefania
PMID:	26352110

159.
Journal:	Cancer Gene Ther. 2015 Sep;22(9):417-30.
Title:	A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.
Author:	Dietel, M\|Johrens, K\|Laffert, M V\|Hummel, M\|Blaker, H\|Pfitzner, B M\|Lehmann, A\|Denkert, C\|Darb-Esfahani, S\|Lenze, D\|Heppner, F L\|Koch, A\|Sers, C\|Klauschen, F\|Anagnostopoulos, I
PMID:	26358176

160.
Journal:	PLoS One. 2015 Sep 16;10(9):e0138141.
Title:	High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.
Author:	van den Broek, Evert\|Dijkstra, Maurits J J\|Krijgsman, Oscar\|Sie, Daoud\|Haan, Josien C\|Traets, Joleen J H\|van de Wiel, Mark A\|Nagtegaal, Iris D\|Punt, Cornelis J A\|Carvalho, Beatriz\|Ylstra, Bauke\|Abeln, Sanne\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	26375816

161.
Journal:	Oncotarget. 2015 Oct 13;6(31):30592-603.
Title:	Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.
Author:	Magliacane, Gilda\|Grassini, Greta\|Bartocci, Paola\|Francaviglia, Ilaria\|Dal Cin, Elena\|Barbieri, Gianluca\|Arrigoni, Gianluigi\|Pecciarini, Lorenza\|Doglioni, Claudio\|Cangi, Maria Giulia
PMID:	26435479

162.
Journal:	Oncotarget. 2015 Oct 27;6(33):34561-72.
Title:	Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Author:	Lieu, Christopher H\|Klauck, Peter J\|Henthorn, Patrick K\|Tentler, John J\|Tan, Aik-Choon\|Spreafico, Anna\|Selby, Heather M\|Britt, Blair C\|Bagby, Stacey M\|Arcaroli, John J\|Messersmith, Wells A\|Pitts, Todd M\|Eckhardt, S Gail
PMID:	26439693

163.
Journal:	Curr Cancer Drug Targets. 2015;15(8):703-15.
Title:	Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice.
Author:	Maurel, Joan\|Postigo, Antonio
PMID:	26452385

164.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4032-8.
Title:	Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.
Author:	Kopetz, Scott\|Desai, Jayesh\|Chan, Emily\|Hecht, Joel Randolph\|O'Dwyer, Peter J\|Maru, Dipen\|Morris, Van\|Janku, Filip\|Dasari, Arvind\|Chung, Woonbook\|Issa, Jean-Pierre J\|Gibbs, Peter\|James, Brian\|Powis, Garth\|Nolop, Keith B\|Bhattacharya, Suman\|Saltz, Leonard
PMID:	26460303

165.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5415-6.
Title:	Optimizing Anti-EGFR Therapy in Colorectal Cancer.
Author:	Salazar, Ramon\|Ciardiello, Fortunato
PMID:	26463710

166.
Journal:	BMC Cancer. 2015 Oct 24;15:779.
Title:	Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.
Author:	Zheng, Gang\|Tseng, Li-Hui\|Chen, Guoli\|Haley, Lisa\|Illei, Peter\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26498038

167.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

168.
Journal:	PLoS One. 2015 Nov 11;10(11):e0142674.
Title:	Absolute Quantification of Endogenous Ras Isoform Abundance.
Author:	Mageean, Craig J\|Griffiths, John R\|Smith, Duncan L\|Clague, Michael J\|Prior, Ian A
PMID:	26560143

169.
Journal:	Ther Adv Med Oncol. 2015 May;7(3):153-69.
Title:	Therapeutic strategy in unresectable metastatic colorectal cancer: an updated review.
Author:	Chibaudel, Benoist\|Tournigand, Christophe\|Bonnetain, Franck\|Richa, Hubert\|Benetkiewicz, Magdalena\|Andre, Thierry\|de Gramont, Aimery
PMID:	26673925

170.
Journal:	Sci Rep. 2015 Dec 22;5:18678.
Title:	Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases.
Author:	Zhang, Jing\|Zheng, Jianming\|Yang, Yinghong\|Lu, Junliang\|Gao, Jie\|Lu, Tao\|Sun, Jian\|Jiang, Hui\|Zhu, Yan\|Zheng, Yuhui\|Liang, Zhiyong\|Liu, Tonghua
PMID:	26691448

171.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):645-9.
Title:	Impact of somatic mutations on patterns of metastasis in colorectal cancer.
Author:	Lipsyc, Marla\|Yaeger, Rona
PMID:	26697197

172.
Journal:	J Clin Pathol. 2016 Mar;69(3):204-8.
Title:	Correlation between DPYD gene variation and KRAS wild type status in colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Meurer, Thuja\|Poetsch, Micaela
PMID:	26281864

173.
Journal:	J Clin Pathol. 2016 Jan;69(1):35-41.
Title:	Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial.
Author:	Richman, Susan D\|Adams, Richard\|Quirke, Phil\|Butler, Rachel\|Hemmings, Gemma\|Chambers, Phil\|Roberts, Helen\|James, Michelle D\|Wozniak, Sue\|Bathia, Riya\|Pugh, Cheryl\|Maughan, Timothy\|Jasani, Bharat
PMID:	26350752

174.
Journal:	J Clin Oncol. 2016 Jan 10;34(2):179-85.
Title:	Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Author:	Allegra, Carmen J\|Rumble, R Bryan\|Hamilton, Stanley R\|Mangu, Pamela B\|Roach, Nancy\|Hantel, Alexander\|Schilsky, Richard L
PMID:	26438111

175.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):849-55.
Title:	Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Author:	Chang, Shih-Ching\|Lin, Pei-Ching\|Lin, Jen-Kou\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai
PMID:	26471487

176.
Journal:	Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title:	Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author:	Crumley, Suzanne M\|Pepper, Kristi L\|Phan, Alexandria T\|Olsen, Randall J\|Schwartz, Mary R\|Portier, Bryce P
PMID:	26536055

177.
Journal:	Virchows Arch. 2016 Apr;468(4):383-96.
Title:	RAS testing in metastatic colorectal cancer: advances in Europe.
Author:	Van Krieken, J Han J M\|Rouleau, Etienne\|Ligtenberg, Marjolijn J L\|Normanno, Nicola\|Patterson, Scott D\|Jung, Andreas
PMID:	26573425

178.
Journal:	Target Oncol. 2016 Jun;11(3):363-70.
Title:	Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing.
Author:	Harle, Alexandre\|Filhine-Tresarrieu, Pierre\|Husson, Marie\|Boidot, Romain\|Rouyer, Marie\|Dubois, Cindy\|Leroux, Agnes\|Merlin, Jean-Louis
PMID:	26661077

179.
Journal:	Tumour Biol. 2016 Jun;37(6):7295-303.
Title:	A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Author:	Bonin, Serena\|Donada, Marisa\|Bussolati, Gianni\|Nardon, Ermanno\|Annaratone, Laura\|Pichler, Martin\|Chiaravalli, Anna Maria\|Capella, Carlo\|Hoefler, Gerald\|Stanta, Giorgio
PMID:	26666825

180.
Journal:	Am J Clin Pathol. 2016 Jan;145(1):29-34.
Title:	Immunohistochemical Detection of NRASQ61R Mutation in Diverse Tumor Types.
Author:	Dias-Santagata, Dora\|Su, Yuhua\|Hoang, Mai P
PMID:	26712868

181.
Journal:	Oncotarget. 2016 Feb 23;7(8):9309-21.
Title:	Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?
Author:	Derangere, Valentin\|Fumet, Jean David\|Boidot, Romain\|Bengrine, Leila\|Limagne, Emeric\|Chevriaux, Angelique\|Vincent, Julie\|Ladoire, Sylvain\|Apetoh, Lionel\|Rebe, Cedric\|Ghiringhelli, Francois
PMID:	26824184

182.
Journal:	Adv Anat Pathol. 2016 Mar;23(2):92-103.
Title:	The State of the Art in Colorectal Cancer Molecular Biomarker Testing.
Author:	Pillai, Raju K\|Lopategui, Jean R\|Dhall, Deepti\|Guindi, Maha\|Slavin, Thomas\|Lofton-Day, Catherine E\|Patterson, Scott D
PMID:	26849815

183.
Journal:	Onco Targets Ther. 2016 Jan 27;9:557-65.
Title:	Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Liu, Jiang\|Hu, Jing\|Cheng, Lei\|Ren, Wei\|Yang, Mi\|Liu, Baorui\|Xie, Li\|Qian, Xiaoping
PMID:	26869800

184.
Journal:	Iran J Pathol. 2016 Winter;11(1):71-5.
Title:	The Report of KRAS Mutation and NRAS Wild Type in a Patient with Thyroid Metastasis from Colon Cancer: a Rare Case Report.
Author:	Payandeh, Mehrdad\|Sadeghi, Masoud\|Sadeghi, Edris
PMID:	26870147

185.
Journal:	Oncotarget. 2016 Apr 12;7(15):19610-9.
Title:	Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment.
Author:	Song, Haa-Na\|Lee, Chung\|Kim, Seung Tae\|Kim, Sun Young\|Kim, Nayoung K D\|Jang, Jiryeon\|Kang, Mihyun\|Jang, Hyojin\|Ahn, Soomin\|Kim, Seok Hyeong\|Park, Yoona\|Cho, Yong Beom\|Heo, Jeong Wook\|Lee, Woo Yong\|Park, Joon Oh\|Lim, Ho Yeong\|Kang, Won Ki\|Park, Young Suk\|P
PMID:	26909603

186.
Journal:	Genes Chromosomes Cancer. 2016 Jun;55(6):505-21.
Title:	Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
Author:	Jesinghaus, Moritz\|Pfarr, Nicole\|Endris, Volker\|Kloor, Matthias\|Volckmar, Anna-Lena\|Brandt, Regine\|Herpel, Esther\|Muckenhuber, Alexander\|Lasitschka, Felix\|Schirmacher, Peter\|Penzel, Roland\|Weichert, Wilko\|Stenzinger, Albrecht
PMID:	26917275

187.
Journal:	BioDrugs. 2016 Apr;30(2):95-104.
Title:	Anti-EGFR Therapy for Metastatic Colorectal Cancer in the Era of Extended RAS Gene Mutational Analysis.
Author:	Kassouf, Elie\|Tabchi, Samer\|Tehfe, Mustapha
PMID:	26927802

188.
Journal:	Cancer. 2016 Jun 1;122(11):1689-96.
Title:	Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/beta-catenin signaling pathway mutations.
Author:	Yuan, Wei\|Zhang, Zhou\|Dai, Binghua\|Wei, Qing\|Liu, Jinjin\|Liu, Yuzhen\|Liu, Yun\|He, Lin\|Zhou, Daizhan
PMID:	26998897

189.
Journal:	Ann Oncol. 2016 Jun;27(6):1055-61.
Title:	Cetuximab continuation after first progression in metastatic colorectal cancer (CAPRI-GOIM): a randomized phase II trial of FOLFOX plus cetuximab versus FOLFOX.
Author:	Ciardiello, F\|Normanno, N\|Martinelli, E\|Troiani, T\|Pisconti, S\|Cardone, C\|Nappi, A\|Bordonaro, A R\|Rachiglio, M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vit
PMID:	27002107

190.
Journal:	Int J Cancer. 2016 Aug 15;139(4):803-11.
Title:	RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Suenaga, Mitsukuni\|Matsusaka, Satoshi\|Konishi, Tsuyoshi\|Akiyoshi, Takashi\|Fujimoto, Yoshiya\|Nagayama, Satoshi\|Fukunaga, Yosuke\|Ueno, Masashi\|Mise, Yoshihiro\|Ishizawa, Takeaki\|Inoue, Yosuke\|Takahashi, Yu\|Saiura, Akio\|Uehara, H
PMID:	27004837

191.
Journal:	Crit Rev Oncol Hematol. 2016 May;101:151-7.
Title:	Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	27017409

192.
Journal:	Int J Colorectal Dis. 2016 May;31(5):973-982.
Title:	Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.
Author:	Lennerz, Jochen K\|van der Sloot, Kimberley W J\|Le, Long Phi\|Batten, Julie M\|Han, Jae Young\|Fan, Kenneth C\|Siegel, Corey A\|Srivastava, Amitabh\|Park, Do Youn\|Chen, Jey-Hsin\|Sands, Bruce E\|Korzenik, Joshua R\|Odze, Robert D\|Dias-Santagata, Dora\|Borger, Darrel
PMID:	27026089

193.
Journal:	J Gastrointest Oncol. 2016 Apr;7(Suppl 1):S11-20.
Title:	Molecular testing to optimize therapeutic decision making in advanced colorectal cancer.
Author:	Semrad, Thomas J\|Kim, Edward J
PMID:	27034809

194.
Journal:	BMC Cancer. 2016 Apr 1;16:260.
Title:	Systematic review: brain metastases from colorectal cancer--Incidence and patient characteristics.
Author:	Christensen, Troels Dreier\|Spindler, Karen-Lise Garm\|Palshof, Jesper Andreas\|Nielsen, Dorte Lisbet
PMID:	27037031

195.
Journal:	Sci Rep. 2016 Apr 14;6:24310.
Title:	Prognostic impact of mutation profiling in patients with stage II and III colon cancer.
Author:	Shen, Yinchen\|Han, Xiaohong\|Wang, Jianfei\|Wang, Shuai\|Yang, Hongying\|Lu, Shih-Hsin\|Shi, Yuankai
PMID:	27074743

196.
Journal:	Qual Life Res. 2016 Oct;25(10):2645-2656.
Title:	Skin toxicity and quality of life during treatment with panitumumab for RAS wild-type metastatic colorectal carcinoma: results from three randomised clinical trials.
Author:	Koukakis, Reija\|Gatta, Francesca\|Hechmati, Guy\|Siena, Salvatore
PMID:	27083443

197.
Journal:	PLoS One. 2016 Apr 21;11(4):e0154038.
Title:	Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.
Author:	Froyen, Guy\|Broekmans, An\|Hillen, Femke\|Pat, Karin\|Achten, Ruth\|Mebis, Jeroen\|Rummens, Jean-Luc\|Willemse, Johan\|Maes, Brigitte
PMID:	27101000

198.
Journal:	Oncotarget. 2016 Jun 21;7(25):37566-37580.
Title:	NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing.
Author:	Chang, Pi-Yueh\|Chen, Jinn-Shiun\|Chang, Nai-Chung\|Chang, Shih-Cheng\|Wang, Mei-Chia\|Tsai, Shu-Hui\|Wen, Ying-Hao\|Tsai, Wen-Sy\|Chan, Err-Cheng\|Lu, Jang-Jih
PMID:	27121310

199.
Journal:	Br J Radiol. 2016 Jul;89(1063):20160212.
Title:	(18)F-FDG PET/CT imaging in rectal cancer: relationship with the RAS mutational status.
Author:	Lovinfosse, Pierre\|Koopmansch, Benjamin\|Lambert, Frederic\|Jodogne, Sebastien\|Kustermans, Gaelle\|Hatt, Mathieu\|Visvikis, Dimitris\|Seidel, Laurence\|Polus, Marc\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	27146067

200.
Journal:	J Mol Diagn. 2016 Jul;18(4):471-9.
Title:	Driver Gene Mutations in Stools of Colorectal Carcinoma Patients Detected by Targeted Next-Generation Sequencing.
Author:	Armengol, Gemma\|Sarhadi, Virinder K\|Ghanbari, Reza\|Doghaei-Moghaddam, Masoud\|Ansari, Reza\|Sotoudeh, Masoud\|Puolakkainen, Pauli\|Kokkola, Arto\|Malekzadeh, Reza\|Knuutila, Sakari
PMID:	27155048

201.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

202.
Journal:	Asian Pac J Cancer Prev. 2016;17(4):1729-32.
Title:	Correlation between RAS Test Results and Prognosis of Metastatic Colorectal Cancer Patients: a Report from Western Iran.
Author:	Payandeh, Mehrdad\|Shazad, Babak\|Sadeghi, Masoud\|Shahbazi, Maryam
PMID:	27221845

203.
Journal:	BMC Cancer. 2016 May 31;16:339.
Title:	ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.
Author:	Segelov, Eva\|Waring, Paul\|Desai, Jayesh\|Wilson, Kate\|Gebski, Val\|Thavaneswaran, Subotheni\|Elez, Elena\|Underhill, Craig\|Pavlakis, Nick\|Chantrill, Lorraine\|Nott, Louise\|Jefford, Michael\|Khasraw, Mustafa\|Day, Fiona\|Wasan, Harpreet\|Ciardiello, Fortunato\|Karap
PMID:	27246726

204.
Journal:	Oncotarget. 2016 Aug 9;7(32):50875-50882.
Title:	Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.
Author:	Javier, Breanna M\|Yaeger, Rona\|Wang, Lu\|Sanchez-Vega, Francisco\|Zehir, Ahmet\|Middha, Sumit\|Sadowska, Justyna\|Vakiani, Efsevia\|Shia, Jinru\|Klimstra, David\|Ladanyi, Marc\|Iacobuzio-Donahue, Christine A\|Hechtman, Jaclyn F
PMID:	27248473

205.
Journal:	Med Oncol. 2016 Jul;33(7):71.
Title:	Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Author:	Li, Zhe-Zhen\|Bai, Long\|Wang, Feng\|Zhang, Zi-Chen\|Wang, Fang\|Zeng, Zhao-Lei\|Zeng, Jun-Bo\|Zhang, Dong-Sheng\|Wang, Feng-Hua\|Wang, Zhi-Qiang\|Li, Yu-Hong\|Shao, Jian-Yong\|Xu, Rui-Hua
PMID:	27270901

206.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1352-61.
Title:	Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
Author:	Lee, Michael S\|McGuffey, Elizabeth J\|Morris, Jeffrey S\|Manyam, Ganiraju\|Baladandayuthapani, Veerabahdran\|Wei, Wei\|Morris, Van K\|Overman, Michael J\|Maru, Dipen M\|Jiang, Zhi-Qin\|Hamilton, Stanley R\|Kopetz, Scott
PMID:	27272216

207.
Journal:	Oncotarget. 2016 Jun 28;7(26):39293-39301.
Title:	Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance.
Author:	Modos, Orsolya\|Reis, Henning\|Niedworok, Christian\|Rubben, Herbert\|Szendroi, Attila\|Szasz, Marcell A\|Timar, Jozsef\|Baghy, Kornelia\|Kovalszky, Ilona\|Golabek, Tomasz\|Chlosta, Piotr\|Okon, Krzysztof\|Peyronnet, Benoit\|Mathieu, Romain\|Shariat, Shahrokh F\|Hollosi
PMID:	27283768

208.
Journal:	Mol Clin Oncol. 2016 Jun;4(6):1017-1024.
Title:	Efficacy of cetuximab-based chemotherapy in metastatic colorectal cancer according to RAS and BRAF mutation subgroups: A meta-analysis.
Author:	Lin, L I\|Chen, Lu-Lu\|Wang, You\|Meng, Xiang-Yu\|Liang, Chen\|Zhou, Fu-Xiang
PMID:	27284437

209.
Journal:	PLoS One. 2016 Jun 14;11(6):e0156659.
Title:	Clinicopathologic and Molecular Features of Colorectal Adenocarcinoma with Signet-Ring Cell Component.
Author:	Wei, Qing\|Wang, Xicheng\|Gao, Jing\|Li, Jian\|Li, Jie\|Qi, Changsong\|Li, Yanyan\|Li, Zhongwu\|Shen, Lin
PMID:	27300552

210.
Journal:	Gastroenterology. 2016 Sep;151(3):440-447.e1.
Title:	Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes.
Author:	Cohen, Stacey A\|Turner, Emily H\|Beightol, Mallory B\|Jacobson, Angela\|Gooley, Ted A\|Salipante, Stephen J\|Haraldsdottir, Sigurdis\|Smith, Christina\|Scroggins, Sheena\|Tait, Jonathan F\|Grady, William M\|Lin, Edward H\|Cohn, David E\|Goodfellow, Paul J\|Arnold, Mar
PMID:	27302833

211.
Journal:	Biomol Detect Quantif. 2016 Jun 6;8:29-32.
Title:	Diagnostic RAS mutation analysis by polymerase chain reaction (PCR).
Author:	Cree, Ian A
PMID:	27335808

212.
Journal:	Cancer J. 2016 May-Jun;22(3):149-55.
Title:	Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.
Author:	Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	27341591

213.
Journal:	Am J Surg. 2016 Sep;212(3):537-544.e3.
Title:	Mutation spectra of RAS gene family in colorectal cancer.
Author:	Chang, Yu-Yao\|Lin, Pei-Ching\|Lin, Hung-Hsin\|Lin, Jen-Kou\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Yang, Shung-Haur\|Liang, Wen-Yih\|Chang, Shih-Ching
PMID:	27394063

214.
Journal:	Virchows Arch. 2016 Oct;469(4):459-64.
Title:	Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.
Author:	Grellety, Thomas\|Gros, Audrey\|Pedeutour, Florence\|Merlio, Jean-Philippe\|Duranton-Tanneur, Valerie\|Italiano, Antoine\|Soubeyran, Isabelle
PMID:	27401719

215.
Journal:	Int J Clin Oncol. 2016 Dec;21(6):1091-1101.
Title:	CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Author:	Zhang, Xiaofei\|Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Takahashi, Hidekazu\|Ouchi, Kota\|Inoue, Masahiro\|Takahashi, Masanobu\|Takahashi, Shin\|Ishioka, Chikashi
PMID:	27435270

216.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

217.
Journal:	Acta Medica (Hradec Kralove). 2016;59(2):54-8.
Title:	Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer.
Author:	Beranek, Martin\|Sirak, Igor\|Vosmik, Milan\|Petera, Jiri\|Drastikova, Monika\|Palicka, Vladimir
PMID:	27526306

218.
Journal:	World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title:	Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author:	Lo Nigro, Cristiana\|Ricci, Vincenzo\|Vivenza, Daniela\|Granetto, Cristina\|Fabozzi, Teresa\|Miraglio, Emanuela\|Merlano, Marco C
PMID:	27570430

219.
Journal:	World J Gastrointest Oncol. 2016 Sep 15;8(9):642-55.
Title:	Role of targeted therapy in metastatic colorectal cancer.
Author:	Ohhara, Yoshihito\|Fukuda, Naoki\|Takeuchi, Satoshi\|Honma, Rio\|Shimizu, Yasushi\|Kinoshita, Ichiro\|Dosaka-Akita, Hirotoshi
PMID:	27672422

220.
Journal:	PLoS One. 2016 Sep 29;11(9):e0163444.
Title:	Multi-Center Evaluation of the Fully Automated PCR-Based Idylla KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer.
Author:	Solassol, Jerome\|Vendrell, Julie\|Markl, Bruno\|Haas, Christian\|Bellosillo, Beatriz\|Montagut, Clara\|Smith, Matthew\|O'Sullivan, Brendan\|D'Haene, Nicky\|Le Mercier, Marie\|Grauslund, Morten\|Melchior, Linea Cecilie\|Burt, Emma\|Cotter, Finbarr\|Stieber, Daniel\|Schm
PMID:	27685259

221.
Journal:	Cancer Sci. 2016 Dec;107(12):1843-1850.
Title:	Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.
Author:	Shitara, Kohei\|Yonesaka, Kimio\|Denda, Tadamichi\|Yamazaki, Kentaro\|Moriwaki, Toshikazu\|Tsuda, Masahiro\|Takano, Toshimi\|Okuda, Hiroyuki\|Nishina, Tomohiro\|Sakai, Kazuko\|Nishio, Kazuto\|Tokunaga, Shoji\|Yamanaka, Takeharu\|Boku, Narikazu\|Hyodo, Ichinosuke\|Muro,
PMID:	27712015

222.
Journal:	Oncotarget. 2016 Nov 8;7(45):73876-73887.
Title:	Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.
Author:	van den Broek, Evert\|Krijgsman, Oscar\|Sie, Daoud\|Tijssen, Marianne\|Mongera, Sandra\|van de Wiel, Mark A\|Belt, Eric J Th\|den Uil, Sjoerd H\|Bril, Herman\|Stockmann, Hein B A C\|Ylstra, Bauke\|Carvalho, Beatriz\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	27729614

223.
Journal:	J Transl Med. 2016 Oct 13;14(1):292.
Title:	Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.
Author:	Palomba, Grazia\|Doneddu, Valentina\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Manca, Antonella\|Casula, Milena\|Colombino, Maria\|Lanzillo, Annamaria\|Defraia, Efisio\|Pazzola, Antonio\|Sanna, Giovanni\|Putzu, Carlo\|Ortu, Salvatore\|Scartozzi, Mario\|Ionta, Maria Ter
PMID:	27737711

224.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):713-720.
Title:	Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others.
Author:	Bupathi, Manojkumar\|Wu, Christina
PMID:	27747085

225.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

226.
Journal:	Br J Cancer. 2016 Nov 8;115(10):1215-1222.
Title:	Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer.
Author:	Karthaus, Meinolf\|Hofheinz, Ralf-Dieter\|Mineur, Laurent\|Letocha, Henry\|Greil, Richard\|Thaler, Josef\|Fernebro, Eva\|Oliner, Kelly S\|Boedigheimer, Michael\|Twomey, Brian\|Zhang, Ying\|Demonty, Gaston\|Kohne, Claus-Henning
PMID:	27764839

227.
Journal:	BMC Cancer. 2016 Nov 18;16(1):902.
Title:	Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
Author:	Orue, Andrea\|Chavez, Valery\|Strasberg-Rieber, Mary\|Rieber, Manuel
PMID:	27863474

228.
Journal:	Int J Surg Case Rep. 2016;29:176-179.
Title:	A case report of successful diagnosis of a pulmonary nodule by a survey of oncogenic mutations; primary lung carcinoma or pulmonary metastasis?
Author:	Haro, Akira\|Kuramitsu, Erina\|Yamamoto, Ichiro\|Fukuyama, Yasuro
PMID:	27865146

229.
Journal:	Asian Pac J Cancer Prev. 2016 Jan 9;17(9):4511-4515.
Title:	Frequency of K-RAS and N-RAS Gene Mutations in Colorectal Cancers in Southeastern Iran
Author:	Mohsen, Naseri\|Ahmadreza, Sebzari\|Fatemeh, Haghighi\|Fatemeh, Hajipoor\|Fariba, Emadian Razavi
PMID:	27880995

230.
Journal:	Int J Mol Sci. 2016 Dec 1;17(12). pii: ijms17122015.
Title:	High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.
Author:	Jeantet, Marion\|Tougeron, David\|Tachon, Gaelle\|Cortes, Ulrich\|Archambaut, Celine\|Fromont, Gaelle\|Karayan-Tapon, Lucie
PMID:	27916952

231.
Journal:	Int J Mol Sci. 2016 Dec 16;17(12). pii: ijms17122117.
Title:	Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers.
Author:	Fontanges, Quitterie\|De Mendonca, Ricardo\|Salmon, Isabelle\|Le Mercier, Marie\|D'Haene, Nicky
PMID:	27999270

232.
Journal:	Genome Med. 2016 Dec 22;8(1):136.
Title:	Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.
Author:	Nagahashi, Masayuki\|Wakai, Toshifumi\|Shimada, Yoshifumi\|Ichikawa, Hiroshi\|Kameyama, Hitoshi\|Kobayashi, Takashi\|Sakata, Jun\|Yagi, Ryoma\|Sato, Nobuaki\|Kitagawa, Yuko\|Uetake, Hiroyuki\|Yoshida, Kazuhiro\|Oki, Eiji\|Kudo, Shin-Ei\|Izutsu, Hiroshi\|Kodama, Keisuke\|
PMID:	28007036

233.
Journal:	J Gastrointest Oncol. 2016 Dec;7(6):882-902.
Title:	Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Author:	Al-Shamsi, Humaid O\|Jones, Jeremy\|Fahmawi, Yazan\|Dahbour, Ibrahim\|Tabash, Aziz\|Abdel-Wahab, Reham\|Abousamra, Ahmed O S\|Shaw, Kenna R\|Xiao, Lianchun\|Hassan, Manal M\|Kipp, Benjamin R\|Kopetz, Scott\|Soliman, Amr S\|McWilliams, Robert R\|Wolff, Robert A
PMID:	28078112

234.
Journal:	World J Gastroenterol. 2016 Dec 28;22(48):10680-10686.
Title:	Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.
Author:	Ghiringhelli, Francois\|Richard, Corentin\|Chevrier, Sandy\|Vegran, Frederique\|Boidot, Romain
PMID:	28082821

235.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2307-2309.
Title:	[A Case of Metastatic Colorectal Cancer with HER2 Overexpression/Amplification].
Author:	Matsumoto, Akio\|Shimada, Yoshifumi\|Yagi, Ryoma\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Ichikawa, Hiroshi\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133304

236.
Journal:	Acta Med Litu. 2016;23(1):24-34.
Title:	Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience.
Author:	Baltruskeviciene, Edita\|Mickys, Ugnius\|Zvirblis, Tadas\|Stulpinas, Rokas\|Pipiriene Zelviene, Terese\|Aleknavicius, Eduardas
PMID:	28356789

237.
Journal:	ESMO Open. 2017 Feb 20;1(6):e000086.
Title:	Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial.
Author:	Martinelli, E\|Cardone, C\|Troiani, T\|Normanno, N\|Pisconti, S\|Sforza, V\|Bordonaro, A R\|Rachiglio, A M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vita, F\|Orditu
PMID:	28848656

238.
Journal:	Appl Immunohistochem Mol Morphol. 2017 Aug;25(7):475-480.
Title:	NRASQ61R Mutation-specific Immunohistochemistry is Highly Specific for Either NRASQ61R or KRASQ61R Mutation in Colorectal Carcinoma.
Author:	Turchini, John\|Andrici, Juliana\|Sioson, Loretta\|Clarkson, Adele\|Watson, Nicole\|Toon, Christopher W\|Shepherd, Phillip\|Ng, Daniel\|Dixon-McIver, Amanda\|Oei, Paul\|Gill, Anthony J
PMID:	26862952

239.
Journal:	Cancer Res Treat. 2017 Jan;49(1):161-167.
Title:	Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.
Author:	Kim, Kyu-Pyo\|Kim, Jeong-Eun\|Hong, Yong Sang\|Ahn, Sung-Min\|Chun, Sung Min\|Hong, Seung-Mo\|Jang, Se Jin\|Yu, Chang Sik\|Kim, Jin Cheon\|Kim, Tae Won
PMID:	27384156

240.
Journal:	Future Oncol. 2017 Jan;13(2):135-144.
Title:	Comparison of the molecular profile of brain metastases from colorectal cancer and corresponding primary tumors.
Author:	Aprile, Giuseppe\|Casagrande, Mariaelena\|De Maglio, Giovanna\|Fontanella, Caterina\|Rihawi, Karim\|Bonotto, Marta\|Pisa, Federica E\|Tuniz, Francesco\|Pizzolitto, Stefano\|Fasola, Gianpiero
PMID:	27578453

241.
Journal:	Gut. 2017 Dec;66(12):2132-2140.
Title:	Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Author:	Sievers, Chelsie K\|Zou, Luli S\|Pickhardt, Perry J\|Matkowskyj, Kristina A\|Albrecht, Dawn M\|Clipson, Linda\|Bacher, Jeffery W\|Pooler, B Dustin\|Moawad, Fouad J\|Cash, Brooks D\|Reichelderfer, Mark\|Vo, Tien N\|Newton, Michael A\|Larget, Bret R\|Halberg, Richard B
PMID:	27609830

242.
Journal:	Clin Cancer Res. 2017 Jun 1;23(11):2742-2749.
Title:	BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.
Author:	Summers, Matthew G\|Smith, Christopher G\|Maughan, Timothy S\|Kaplan, Richard\|Escott-Price, Valentina\|Cheadle, Jeremy P
PMID:	27815357

243.
Journal:	Int J Cancer. 2017 Feb 15;140(4):922-929.
Title:	EGFR gene copy number predicts response to anti-EGFR treatment in RAS wild type and RAS/BRAF/PIK3CA wild type metastatic colorectal cancer.
Author:	Algars, Annika\|Sundstrom, Jari\|Lintunen, Minnamaija\|Jokilehto, Terhi\|Kytola, Soili\|Kaare, Milja\|Vainionpaa, Reetta\|Orpana, Arto\|Osterlund, Pia\|Ristimaki, Ari\|Carpen, Olli\|Ristamaki, Raija
PMID:	27879995

244.
Journal:	Anticancer Res. 2017 Jan;37(1):239-247.
Title:	Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takenoya, Takashi\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28011498

245.
Journal:	Hum Pathol. 2017 Apr;62:91-98.
Title:	Analysis of KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer.
Author:	Reggiani Bonetti, Luca\|Barresi, Valeria\|Bettelli, Stefania\|Caprera, Cecilia\|Manfredini, Samantha\|Maiorana, Antonio
PMID:	28025078

246.
Journal:	Ann Oncol. 2017 Apr 1;28(4):824-830.
Title:	Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients.
Author:	Taieb, J\|Balogoun, R\|Le Malicot, K\|Tabernero, J\|Mini, E\|Folprecht, G\|Van Laethem, J-L\|Emile, J-F\|Mulot, C\|Fratte, S\|Levache, C-B\|Saban-Roche, L\|Thaler, J\|Petersen, L N\|Bridgewater, J\|Perkins, G\|Lepage, C\|Van Cutsem, E\|Zaanan, A\|Laurent-Puig, P
PMID:	28031175

247.
Journal:	J Natl Compr Canc Netw. 2017 Jan;15(1):3-8.
Title:	Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.
Author:	Parikh, Aparna\|Atreya, Chloe\|Korn, W Michael\|Venook, Alan P
PMID:	28040715

248.
Journal:	Future Oncol. 2017 Apr;13(10):919-934.
Title:	Translating genomic profiling to gastrointestinal cancer treatment.
Author:	Harada, Kazuto\|Mizrak Kaya, Dilsa\|Shimodaira, Yusuke\|Song, Shumei\|Baba, Hideo\|Ajani, Jaffer A
PMID:	28067073

249.
Journal:	BMC Cancer. 2017 Jan 9;17(1):38.
Title:	Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
Author:	Nakayama, Izuma\|Shinozaki, Eiji\|Matsushima, Tomohiro\|Wakatsuki, Takeru\|Ogura, Mariko\|Ichimura, Takashi\|Ozaka, Masato\|Takahari, Daisuke\|Suenaga, Mitsukuni\|Chin, Keisho\|Mizunuma, Nobuyuki\|Yamaguchi, Kensei
PMID:	28068936

250.
Journal:	Med Oncol. 2017 Feb;34(2):26.
Title:	KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma.
Author:	Cicenas, Jonas\|Tamosaitis, Linas\|Kvederaviciute, Kotryna\|Tarvydas, Ricardas\|Staniute, Gintare\|Kalyan, Karthik\|Meskinyte-Kausiliene, Edita\|Stankevicius, Vaidotas\|Valius, Mindaugas
PMID:	28074351

251.
Journal:	Bull Exp Biol Med. 2017 Jan;162(3):375-378.
Title:	Detection of Rare Mutations by Routine Analysis of KRAS, NRAS, and BRAF Oncogenes.
Author:	Mikhailenko, D S\|Efremov, G D\|Safronova, N Yu\|Strelnikov, V V\|Alekseev, B Ya
PMID:	28091917

252.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jan 25;20(1):24-27.
Title:	[Improvement of prognostic and predictive network of colorectal cancer based upon the 8th edition of AJCC colorectal cancer staging system].
Author:	Yao, Hongwei\|Wu, Hongwei\|Liu, Yinhua
PMID:	28105615

253.
Journal:	Oncotarget. 2017 Mar 14;8(11):17810-17818.
Title:	EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics.
Author:	Yamamoto, Itaru\|Nosho, Katsuhiko\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Ishigami, Keisuke\|Ishiguro, Kazuya\|Mitsuhashi, Kei\|Maruyama, Reo\|Koide, Hideyuki\|Okuda, Hiroyuki\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Okita, Kenji\|Takemasa, Ichiro\|Yama
PMID:	28147317

254.
Journal:	J Clin Pathol. 2017 Aug;70(8):702-711.
Title:	QMC-PCRx: a novel method for rapid mutation detection.
Author:	Ebili, Henry O\|Hassall, James\|Asiri, Abutaleb\|Ham-Karim, Hersh\|Fadhil, Wakkas\|Agboola, Ayodeji Johnson\|Ilyas, Mohammad
PMID:	28153952

255.
Journal:	Br J Cancer. 2017 Mar 14;116(6):802-810.
Title:	Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients.
Author:	Malapelle, Umberto\|Mayo de-Las-Casas, Clara\|Rocco, Danilo\|Garzon, Monica\|Pisapia, Pasquale\|Jordana-Ariza, Nuria\|Russo, Maria\|Sgariglia, Roberta\|De Luca, Caterina\|Pepe, Francesco\|Martinez-Bueno, Alejandro\|Morales-Espinosa, Daniela\|Gonzalez-Cao, Maria\|Karac
PMID:	28170370

256.
Journal:	Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title:	Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author:	Lee, Sung Hak\|Jung, Seung Hyun\|Kim, Tae-Min\|Rhee, Je-Keun\|Park, Hyeon-Chun\|Kim, Min Sung\|Kim, Sung Soo\|An, Chang Hyeok\|Lee, Sug Hyung\|Chung, Yeun-Jun
PMID:	28179590

257.
Journal:	Hum Pathol. 2017 Jul;65:21-30.
Title:	KRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior.
Author:	Jang, Sejin\|Hong, Mineui\|Shin, Mi Kyung\|Kim, Byung Chun\|Shin, Hyung-Sik\|Yu, Eunsil\|Hong, Seung-Mo\|Kim, Jihun\|Chun, Sung-Min\|Kim, Tae-Im\|Choi, Kyung-Chan\|Ko, Young Woong\|Kim, Jeong Won
PMID:	28188750

258.
Journal:	J Pathol Transl Med. 2017 Mar;51(2):103-121.
Title:	Molecular Testing for Gastrointestinal Cancer.
Author:	Lee, Hye Seung\|Kim, Woo Ho\|Kwak, Yoonjin\|Koh, Jiwon\|Bae, Jeong Mo\|Kim, Kyoung-Mee\|Chang, Mee Soo\|Han, Hye Seung\|Kim, Joon Mee\|Kim, Hwal Woong\|Chang, Hee Kyung\|Choi, Young Hee\|Park, Ji Y\|Gu, Mi Jin\|Lhee, Min Jin\|Kim, Jung Yeon\|Kim, Hee Sung\|Cho, Mee-Yon
PMID:	28219002

259.
Journal:	Tumour Biol. 2017 Feb;39(2):1010428317692265.
Title:	Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Bp, Manasa\|Minhas, Sachin\|Shokeen, Yogender\|Aggarwal, Shyam
PMID:	28222664

260.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

261.
Journal:	PLoS One. 2017 Mar 7;12(3):e0173345.
Title:	Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer.
Author:	Mehrvarz Sarshekeh, Amir\|Advani, Shailesh\|Overman, Michael J\|Manyam, Ganiraju\|Kee, Bryan K\|Fogelman, David R\|Dasari, Arvind\|Raghav, Kanwal\|Vilar, Eduardo\|Manuel, Shanequa\|Shureiqi, Imad\|Wolff, Robert A\|Patel, Keyur P\|Luthra, Raja\|Shaw, Kenna\|Eng, Cathy\|Ma
PMID:	28267766

262.
Journal:	J Natl Compr Canc Netw. 2017 Mar;15(3):370-398.
Title:	Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
Author:	Benson, Al B 3rd\|Venook, Alan P\|Cederquist, Lynette\|Chan, Emily\|Chen, Yi-Jen\|Cooper, Harry S\|Deming, Dustin\|Engstrom, Paul F\|Enzinger, Peter C\|Fichera, Alessandro\|Grem, Jean L\|Grothey, Axel\|Hochster, Howard S\|Hoffe, Sarah\|Hunt, Steven\|Kamel, Ahmed\|Kirilcu
PMID:	28275037

263.
Journal:	J Clin Pathol. 2017 Jul;70(7):610-614.
Title:	Validating a fully automated real-time PCR-based system for use in the molecular diagnostic analysis of colorectal carcinoma: a comparison with NGS and IHC.
Author:	Colling, Richard\|Wang, Lai Mun\|Soilleux, Elizabeth
PMID:	28292978

264.
Journal:	J Clin Pathol. 2017 Aug;70(8):720-723.
Title:	Intratumorous heterogeneity for RAS mutations in a treatment-naive colorectal tumour.
Author:	Lunke, Sebastian\|Lee, Belinda\|Kranz, Sevastjan\|Gibbs, Peter\|Waring, Paul\|Christie, Michael
PMID:	28314739

265.
Journal:	Tumour Biol. 2017 Mar;39(3):1010428317692246.
Title:	Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Author:	Kleist, Britta\|Meurer, Thuja\|Poetsch, Micaela
PMID:	28345467

266.
Journal:	Arch Pathol Lab Med. 2017 Apr;141(4):564-568.
Title:	SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma.
Author:	Lasota, Jerzy\|Kowalik, Artur\|Felisiak-Golabek, Anna\|Inaguma, Shingo\|Wang, Zeng-Feng\|Pieciak, Liliana\|Zieba, Sebastian\|Peksa, Rafal\|Kopczynski, Janusz\|Okon, Krzysztof\|Waloszczyk, Piotr\|Gozdz, Stanislaw\|Biernat, Wojciech\|Miettinen, Markku
PMID:	28353383

267.
Journal:	Cancer Med. 2017 May;6(5):1023-1035.
Title:	DNA methylation epigenotype and clinical features of NRAS-mutation(+) colorectal cancer.
Author:	Takane, Kiyoko\|Akagi, Kiwamu\|Fukuyo, Masaki\|Yagi, Koichi\|Takayama, Tadatoshi\|Kaneda, Atsushi
PMID:	28378457

268.
Journal:	Oncotarget. 2017 Jul 25;8(30):49076-49083.
Title:	The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients.
Author:	Peng, Junjie\|Huang, Dan\|Poston, Graeme\|Ma, Xiaoji\|Wang, Renjie\|Sheng, Weiqi\|Zhou, Xiaoyan\|Zhu, Xiaoli\|Cai, Sanjun
PMID:	28416767

269.
Journal:	Pathology. 2017 Jun;49(4):387-390.
Title:	NRASQ61R immunohistochemistry detects both NRASQ61R and KRASQ61R mutations in colorectal cancer.
Author:	Jhuang, Jie-Yang\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Cheng, Mei-Ling\|Liau, Jau-Yu\|Tsai, Jia-Huei
PMID:	28433252

270.
Journal:	Clin Cancer Res. 2017 Aug 15;23(16):4753-4760.
Title:	Clinical Features and Outcomes of Patients with Colorectal Cancers Harboring NRAS Mutations.
Author:	Cercek, Andrea\|Braghiroli, Maria Ignez\|Chou, Joanne F\|Hechtman, Jaclyn F\|Kemeny, Nancy\|Saltz, Leonard\|Capanu, Marinela\|Yaeger, Rona
PMID:	28446505

271.
Journal:	Acta Oncol. 2017 May;56(5):639-645.
Title:	Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Hogdall, Estrid\|Poulsen, Tim Svenstrup\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Christensen, Ib Jarle\|Nielsen, Dorte
PMID:	28447565

272.
Journal:	Mol Clin Oncol. 2017 Mar;6(3):403-408.
Title:	Role of RAS mutation status as a prognostic factor for patients with advanced colorectal cancer treated with first-line chemotherapy based on fluoropyrimidines and oxaliplatin, with or without bevavizumab: A retrospective analysis.
Author:	Garde Noguera, Javier\|Jantus-Lewintre, Eloisa\|Gil-Raga, Mireia\|Evgenyeva, Elena\|Macia Escalante, Sonia\|Llombart-Cussac, Antonio\|Camps Herrero, Carlos
PMID:	28451421

273.
Journal:	Oncologist. 2017 Jul;22(7):774-779.
Title:	Detection of an ALK Fusion in Colorectal Carcinoma by Hybrid Capture-Based Assay of Circulating Tumor DNA.
Author:	Lai, Andrea Z\|Schrock, Alexa B\|Erlich, Rachel L\|Ross, Jeffrey S\|Miller, Vincent A\|Yakirevich, Evgeny\|Ali, Siraj M\|Braiteh, Fadi
PMID:	28507204

274.
Journal:	Cancer. 2017 Sep 15;123(18):3513-3523.
Title:	Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Author:	Lee, Dae-Won\|Han, Sae-Won\|Cha, Yongjun\|Bae, Jeong Mo\|Kim, Hwang-Phill\|Lyu, Jaemyun\|Han, Hyojun\|Kim, Hyoki\|Jang, Hoon\|Bang, Duhee\|Huh, Iksoo\|Park, Taesung\|Won, Jae-Kyung\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	28513830

275.
Journal:	Oncol Rep. 2017 Jul;38(1):263-270.
Title:	EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells.
Author:	Cuyas, Elisabet\|Queralt, Bernardo\|Martin-Castillo, Begona\|Bosch-Barrera, Joaquim\|Menendez, Javier A
PMID:	28560458

276.
Journal:	Mol Oncol. 2017 Sep;11(9):1263-1272.
Title:	Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Author:	Dienstmann, Rodrigo\|Elez, Elena\|Argiles, Guillem\|Matos, Ignacio\|Sanz-Garcia, Enrique\|Ortiz, Carolina\|Macarulla, Teresa\|Capdevila, Jaume\|Alsina, Maria\|Sauri, Tamara\|Verdaguer, Helena\|Vilaro, Marta\|Ruiz-Pace, Fiorella\|Viaplana, Cristina\|Garcia, Ariadna\|Land
PMID:	28618197

277.
Journal:	Br J Cancer. 2017 Jul 25;117(3):358-366.
Title:	Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.
Author:	Mariani, Sara\|Bertero, Luca\|Osella-Abate, Simona\|Di Bello, Cristiana\|Francia di Celle, Paola\|Coppola, Vittoria\|Sapino, Anna\|Cassoni, Paola\|Marchio, Caterina
PMID:	28618430

278.
Journal:	Virchows Arch. 2017 Dec;471(6):721-729.
Title:	RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016).
Author:	Richman, Susan D\|Fairley, Jennifer\|Butler, Rachel\|Deans, Zandra C
PMID:	28653203

279.
Journal:	Int J Biol Markers. 2017 Oct 31;32(4):e474-e477.
Title:	Discordance in RAS mutations between primary colon tumor and metastases: a real event or a matter of methodology?
Author:	De Stefano, Alfonso\|Rosanova, Mario\|Malapelle, Umberto\|Martini, Maurizio\|De Falco, Stefano\|Attademo, Laura\|Fiore, Giovanni\|Cenci, Tonia\|Bellevicine, Claudio\|De Placido, Sabino\|Troncone, Giancarlo\|Carlomagno, Chiara
PMID:	28665451

280.
Journal:	Tumour Biol. 2017 Jul;39(7):1010428317709638.
Title:	Oncogene mutation profile predicts tumor regression and survival in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy and radical surgery.
Author:	Peng, Jianhong\|Lin, Junzhong\|Qiu, Miaozhen\|Zhao, Yujie\|Deng, Yuxiang\|Shao, Jianyong\|Ding, Peirong\|Zhang, Huizhong\|Wan, Desen\|Lu, Zhenhai\|Pan, Zhizhong
PMID:	28671043

281.
Journal:	Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title:	Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author:	Chang, Chu-Cheng\|Lin, Pei-Ching\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Lin, Hung-Hsin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	28678173

282.
Journal:	Mol Clin Oncol. 2017 Jul;7(1):113-120.
Title:	Heterogeneity in the colorectal primary tumor and the synchronous resected liver metastases prior to and after treatment with an anti-EGFR monoclonal antibody.
Author:	Adua, Daniela\|Di Fabio, Francesca\|Ercolani, Giorgio\|Fiorentino, Michelangelo\|Gruppioni, Elisa\|Altimari, Annalisa\|Rojas Limpe, Fabiola Lorena\|Normanno, Nicola\|Pinna, Antonio Daniele\|Pinto, Carmine
PMID:	28685087

283.
Journal:	Br J Cancer. 2017 Oct 24;117(9):1286-1294.
Title:	Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Author:	Gollins, Simon\|West, Nick\|Sebag-Montefiore, David\|Myint, Arthur Sun\|Saunders, Mark\|Susnerwala, Shabbir\|Quirke, Phil\|Essapen, Sharadah\|Samuel, Leslie\|Sizer, Bruce\|Worlding, Jane\|Southward, Katie\|Hemmings, Gemma\|Tinkler-Hundal, Emma\|Taylor, Morag\|Bottomley,
PMID:	28859058

284.
Journal:	Cancer Lett. 2017 Dec 1;410:92-99.
Title:	Major challenges related to tumor biological characteristics in accurate mutation detection of colorectal cancer by next-generation sequencing.
Author:	Li, Weihua\|Qiu, Tian\|Guo, Lei\|Ying, Jianming
PMID:	28942013

285.
Journal:	Br J Cancer. 2017 Dec 5;117(12):1819-1827.
Title:	Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author:	Lievre, Astrid\|Ouine, Berengere\|Canet, Jim\|Cartier, Aurelie\|Amar, Yael\|Cacheux, Wulfran\|Mariani, Odette\|Guimbaud, Rosine\|Selves, Janick\|Lecomte, Thierry\|Guyetant, Serge\|Bieche, Ivan\|Berger, Frederique\|de Koning, Leanne
PMID:	29024937

286.
Journal:	Oncotarget. 2017 Apr 11;8(39):64999-65008.
Title:	Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment.
Author:	Moorcraft, Sing Y\|Jones, Thomas\|Walker, Brian A\|Ladas, George\|Kalaitzaki, Eleftheria\|Yuan, Lina\|Begum, Ruwaida\|Eltahir, Zakaria\|Wotherspoon, Andrew\|Montero-Fernandez, Angeles\|Teixeira Mendes, Larissa S\|Gonzalez de Castro, David\|Wilson, Sanna Hulkki\|Prosze
PMID:	29029407

287.
Journal:	Oncotarget. 2017 Jun 20;8(39):65407-65413.
Title:	Colorectal carcinoma with osseous metaplasia.
Author:	Liu, Xibo\|Xu, Jinghong\|Chen, Lirong
PMID:	29029440

288.
Journal:	Chin J Cancer. 2017 Oct 16;36(1):81.
Title:	Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study.
Author:	Wang, Xicheng\|Wei, Qing\|Gao, Jing\|Li, Jian\|Li, Jie\|Gong, Jifang\|Li, Yanyan\|Shen, Lin
PMID:	29037218

289.
Journal:	Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Dec;161(4):360-368.
Title:	Derivation and basic characterization of colorectal carcinoma primary cell lines.
Author:	Krbal, Lukas\|Soukup, Jiri\|Stanislav, John\|Hanusova, Veronika
PMID:	29042709

290.
Journal:	Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title:	Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author:	Jung, Joohee\|Kim, Jisup\|Lim, Hyun Kyung\|Kim, Kyoung Mee\|Lee, Yun Sun\|Park, Joon Seong\|Yoon, Dong Sup
PMID:	29094026

291.
Journal:	BMC Gastroenterol. 2017 Nov 23;17(1):121.
Title:	Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer.
Author:	Kim, Dalyong\|Kim, Sun Young\|Lee, Ji Sung\|Hong, Yong Sang\|Kim, Jeong Eun\|Kim, Kyu-Pyo\|Kim, Jihun\|Jang, Se Jin\|Yoon, Young-Kwang\|Kim, Tae Won
PMID:	29169325

292.
Journal:	BMC Cancer. 2017 Nov 28;17(1):798.
Title:	Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review.
Author:	Han van Krieken, J\|Kafatos, George\|Bennett, James\|Mineur, Laurent\|Tomasek, Jiri\|Rouleau, Etienne\|Fabian, Pavel\|De Maglio, Giovanna\|Garcia-Alfonso, Pilar\|Aprile, Giuseppe\|Parkar, Parijan\|Downey, Gerald\|Demonty, Gaston\|Trojan, Jorg
PMID:	29183279

293.
Journal:	Ann Biol Clin (Paris). 2017 Dec 1;75(6):607-618.
Title:	Detection of RAS mutations in circulating tumor cells: applications in colorectal cancer and prospects.
Author:	Denis, Jerome Alexandre\|Lacorte, Jean-Marc
PMID:	29192596

294.
Journal:	Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title:	Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Author:	Shimada, Yoshifumi\|Kameyama, Hitoshi\|Nagahashi, Masayuki\|Ichikawa, Hiroshi\|Muneoka, Yusuke\|Yagi, Ryoma\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Hayashida, Tetsu\|Takaishi
PMID:	29212173

295.
Journal:	Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title:	Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author:	Hou, Helei\|Liu, Dong\|Zhang, Chuantao\|Jiang, Yanxia\|Lu, Guifang\|Zhou, Na\|Yang, Xiaonan\|Zhang, Xiaoping\|Li, Zhuokun\|Zhu, Hongmei\|Qian, Zhaoyang\|Zhang, Xiaochun
PMID:	29285234

296.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Feb;26(2):140-146.
Title:	The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Author:	Skalova, Alena\|Sar, Aylin\|Laco, Jan\|Metelkova, Alena\|Miesbauerova, Marketa\|Steiner, Petr\|Svajdler, Marian\|Michal, Michal
PMID:	27258560

297.
Journal:	J Gastrointest Cancer. 2018 Jun;49(2):124-131.
Title:	Clinicopathological Associations of K-RAS and N-RAS Mutations in Indonesian Colorectal Cancer Cohort.
Author:	Levi, Michael\|Prayogi, Gintang\|Sastranagara, Farid\|Sudianto, Edi\|Widjajahakim, Grace\|Gani, Winiarti\|Mahanadi, Albert\|Agnes, Jocelyn\|Khairunisa, Bela Haifa\|Utomo, Ahmad R
PMID:	28044264

298.
Journal:	J Cell Physiol. 2018 Mar;233(3):2058-2066.
Title:	Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer.
Author:	Bahrami, Afsane\|Hassanian, Seyed Mahdi\|ShahidSales, Soodabeh\|Farjami, Zahra\|Hasanzadeh, Malihe\|Anvari, Kazem\|Aledavood, Amir\|Maftouh, Mina\|Ferns, Gordon A\|Khazaei, Majid\|Avan, Amir
PMID:	28262927

299.
Journal:	J Clin Pathol. 2018 Apr;71(4):336-343.
Title:	Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue.
Author:	Johnston, Louise\|Power, Michael\|Sloan, Philip\|Long, Anna\|Silmon, Angela\|Chaffey, Ben\|Lisgo, Andrea Jane\|Little, Liam\|Vercauteren, Ellen\|Steiniche, Torben\|Meyer, Tine\|Simpson, John
PMID:	28899979

300.
Journal:	Ann Oncol. 2018 Jan 1;29(1):112-118.
Title:	RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
Author:	Normanno, N\|Esposito Abate, R\|Lambiase, M\|Forgione, L\|Cardone, C\|Iannaccone, A\|Sacco, A\|Rachiglio, A M\|Martinelli, E\|Rizzi, D\|Pisconti, S\|Biglietto, M\|Bordonaro, R\|Troiani, T\|Latiano, T P\|Giuliani, F\|Leo, S\|Rinaldi, A\|Maiello, E\|Ciardiello, F
PMID:	28950295

301.
Journal:	Mod Pathol. 2018 Feb;31(2):343-349.
Title:	Optimal detection of clinically relevant mutations in colorectal carcinoma: sample pooling overcomes intra-tumoral heterogeneity.
Author:	Nelson, Andrew C\|Boone, Jamie\|Cartwright, David\|Thyagarajan, Bharat\|Kincaid, Robyn\|Lambert, Aaron P\|Karnuth, Kylene\|Henzler, Christine\|Yohe, Sophia
PMID:	29027537

302.
Journal:	Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):365-375.
Title:	FDG PET/CT radiomics for predicting the outcome of locally advanced rectal cancer.
Author:	Lovinfosse, Pierre\|Polus, Marc\|Van Daele, Daniel\|Martinive, Philippe\|Daenen, Frederic\|Hatt, Mathieu\|Visvikis, Dimitris\|Koopmansch, Benjamin\|Lambert, Frederic\|Coimbra, Carla\|Seidel, Laurence\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	29046927

303.
Journal:	Mod Pathol. 2018 Mar;31(3):517-526.
Title:	Association between clinicopathological characteristics and RAS mutation in colorectal cancer.
Author:	Rimbert, Johan\|Tachon, Gaelle\|Junca, Audelaure\|Villalva, Claire\|Karayan-Tapon, Lucie\|Tougeron, David
PMID:	29052598

304.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):73-79.
Title:	Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Author:	Chiu, Joanne W\|Krzyzanowska, Monika K\|Serra, Stefano\|Knox, Jennifer J\|Dhani, Neesha C\|Mackay, Helen\|Hedley, David\|Moore, Malcolm\|Liu, Geoffrey\|Burkes, Ronald L\|Brezden-Masley, Christine\|Roehrl, Michael H\|Craddock, Kenneth J\|Tsao, Ming-Sound\|Zhang, Tong\|Yu
PMID:	29128266

305.
Journal:	Pharmacol Rev. 2018 Jan;70(1):1-11.
Title:	RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.
Author:	Yan, Chao\|Theodorescu, Dan
PMID:	29196555

306.
Journal:	Mol Cancer Res. 2018 Mar;16(3):486-495.
Title:	Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.
Author:	Drew, David A\|Mo, Allen\|Grady, James J\|Stevens, Richard G\|Levine, Joel B\|Brenner, Bruce M\|Anderson, Joseph C\|Forouhar, Faripour\|O'Brien, Michael J\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	29222172

307.
Journal:	Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title:	Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author:	Adams, Richard\|Brown, Ewan\|Brown, Louise\|Butler, Rachel\|Falk, Stephen\|Fisher, David\|Kaplan, Richard\|Quirke, Phil\|Richman, Susan\|Samuel, Leslie\|Seligmann, Jenny\|Seymour, Matt\|Shiu, Kai Keen\|Wasan, Harpreet\|Wilson, Richard\|Maughan, Tim
PMID:	29254887

308.
Journal:	Mod Pathol. 2018 May;31(5):829-839.
Title:	Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
Author:	Jesinghaus, Moritz\|Konukiewitz, Bjorn\|Foersch, Sebastian\|Stenzinger, Albrecht\|Steiger, Katja\|Muckenhuber, Alexander\|Gross, Claudia\|Mollenhauer, Martin\|Roth, Wilfried\|Detlefsen, Sonke\|Weichert, Wilko\|Kloppel, Gunter\|Pfarr, Nicole\|Schlitter, Anna Melissa
PMID:	29327707

309.
Journal:	Virchows Arch. 2018 May;472(5):717-725.
Title:	RAS testing for colorectal cancer patients is reliable in European laboratories that pass external quality assessment.
Author:	Tack, V\|Ligtenberg, M J L\|Siebers, A G\|Rombout, P D M\|Dabir, P D\|Weren, R D A\|van Krieken, J H J M\|Dequeker, E M C
PMID:	29333594

310.
Journal:	Eur Radiol. 2018 May;28(5):2058-2067.
Title:	Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer?
Author:	Yang, Lei\|Dong, Di\|Fang, Mengjie\|Zhu, Yongbei\|Zang, Yali\|Liu, Zhenyu\|Zhang, Hongmei\|Ying, Jianming\|Zhao, Xinming\|Tian, Jie
PMID:	29335867

311.
Journal:	Acta Oncol. 2018 Aug;57(8):1057-1062.
Title:	Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Poulsen, Tim Svenstrup\|Hogdall, Estrid\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Nielsen, Dorte
PMID:	29380640

312.
Journal:	Hum Pathol. 2018 Apr;74:178-182.
Title:	KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
Author:	Tessitore, Alessandra\|Bruera, Gemma\|Mastroiaco, Valentina\|Cannita, Katia\|Cortellini, Alessio\|Cocciolone, Valentina\|Dal Mas, Antonella\|Calvisi, Giuseppe\|Zazzeroni, Francesca\|Ficorella, Corrado\|Ricevuto, Enrico\|Alesse, Edoardo
PMID:	29409955

313.
Journal:	Pathobiology. 2018;85(1-2):72-84.
Title:	Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?
Author:	Sagaert, Xavier\|Vanstapel, Arno\|Verbeek, Sanne
PMID:	29414818

314.
Journal:	PeerJ. 2018 Feb 5;6:e4341.
Title:	Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China.
Author:	Zhang, Xiangyan\|Ran, Wenwen\|Wu, Jie\|Li, Hong\|Liu, Huamin\|Wang, Lili\|Xiao, Yujing\|Wang, Xiaonan\|Li, Yujun\|Xing, Xiaoming
PMID:	29423347

315.
Journal:	Cancer Discov. 2018 Apr;8(4):428-443.
Title:	Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF(V600E)-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Andre, Thierry\|Atreya, Chloe E\|Schellens, Jan H M\|Yoshino, Takayuki\|Bendell, Johanna C\|Hollebecque, Antoine\|McRee, Autumn J\|Siena, Salvatore\|Middleton, Gary\|Muro, Kei\|Gordon, Michael S\|Tabernero, Josep\|Yaeger, Rona\|O'Dwyer, Peter J\|Humble
PMID:	29431699

316.
Journal:	Clin Drug Investig. 2018 Jun;38(6):553-562.
Title:	First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author:	Moiseyenko, Vladimir M\|Moiseyenko, Fedor V\|Yanus, Grigoriy A\|Kuligina, Ekatherina Sh\|Sokolenko, Anna P\|Bizin, Ilya V\|Kudriavtsev, Alexey A\|Aleksakhina, Svetlana N\|Volkov, Nikita M\|Chubenko, Vyacheslav A\|Kozyreva, Kseniya S\|Kramchaninov, Mikhail M\|Zhuravle
PMID:	29470838

317.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):235-242.
Title:	Systemic Therapy for Colon Cancer.
Author:	Wu, Christina
PMID:	29496087

318.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):349-365.
Title:	Clinical Trials and Progress in Metastatic Colon Cancer.
Author:	Mody, Kabir\|Bekaii-Saab, Tanios
PMID:	29496094

319.
Journal:	Oncologist. 2018 Aug;23(8):912-918.
Title:	Phase II Study of Preoperative Treatment with External Radiotherapy Plus Panitumumab in Low-Risk, Locally Advanced Rectal Cancer (RaP Study/STAR-03).
Author:	Pinto, Carmine\|Di Bisceglie, Maurizio\|Di Fabio, Francesca\|Bochicchio, Annamaria\|Latiano, Tiziana\|Cordio, Stefano\|Rosati, Gerardo\|Aschele, Carlo\|Marino, Antonella\|Bergamo, Francesca\|Bustreo, Sara\|Frassineti, Luca\|Ciardiello, Fortunato\|Damato, Angela\|Giaqui
PMID:	29523646

320.
Journal:	Clin Colorectal Cancer. 2018 Jun;17(2):e331-e352.
Title:	Phosphorylation of p70 Ribosomal Protein S6 Kinase beta-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.
Author:	Wiesweg, Marcel\|Reis, Henning\|Koster, Tobias\|Goetz, Moritz\|Worm, Karl\|Herold, Thomas\|Paul, Andreas\|Dechene, Alexander\|Schumacher, Brigitte\|Markus, Peter\|Virchow, Isabel\|Kostbade, Karina\|Wolf, Nathalie\|Zaun, Gregor\|Metzenmacher, Martin\|Schmid, Kurt W\|Schul
PMID:	29526493

321.
Journal:	Am J Med Sci. 2018 Mar;355(3):220-227.
Title:	Use of Liquid Biopsy in Monitoring Colorectal Cancer Progression Shows Strong Clinical Correlation.
Author:	Sun, Qiushi\|Liu, Yuan\|Liu, Bo\|Liu, Yingying
PMID:	29549923

322.
Journal:	World J Surg Oncol. 2018 Mar 27;16(1):67.
Title:	FOLFIRI plus panitumumab in the treatment of wild-type KRAS and wild-type NRAS metastatic colorectal cancer.
Author:	Geredeli, Caglayan\|Yasar, Nurgul
PMID:	29587749

323.
Journal:	JAMA Oncol. 2018 Jun 1;4(6):806-813.
Title:	Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.
Author:	Hampel, Heather\|Pearlman, Rachel\|Beightol, Mallory\|Zhao, Weiqiang\|Jones, Daniel\|Frankel, Wendy L\|Goodfellow, Paul J\|Yilmaz, Ahmet\|Miller, Kristin\|Bacher, Jason\|Jacobson, Angela\|Paskett, Electra\|Shields, Peter G\|Goldberg, Richard M\|de la Chapelle, Albert\|S
PMID:	29596542

324.
Journal:	Cesk Patol. 2018 Spring;54(1):17-21.
Title:	[Prediction of EGFR blockade responses in metastatic colorectal carcinoma].
Author:	Fabian, Pavel\|Nemecek, Radim
PMID:	29631407

325.
Journal:	Gastroenterol Res Pract. 2018 Jan 31;2018:4585802.
Title:	Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Yang, Dongyang\|Ma, Dong
PMID:	29643917

326.
Journal:	Sci Rep. 2018 Apr 17;8(1):6076.
Title:	Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.
Author:	Guo, Fang\|Gong, Hai\|Zhao, Huanhuan\|Chen, Jing\|Zhang, Yiming\|Zhang, Lihua\|Shi, Xin\|Zhang, Aifeng\|Jin, Hui\|Zhang, Jianqiong\|He, Youji
PMID:	29666387

327.
Journal:	Middle East J Dig Dis. 2018 Jan;10(1):18-23.
Title:	Frequency of NRAS Gene Mutation in Wild Type KRAS and BRAF Colorectal Cancers; a Single Center Study.
Author:	Momenzadeh, Hooria\|Mirzai, Mitra\|Jowkar, Zahra\|Geramizadeh, Bita
PMID:	29682243

328.
Journal:	Virchows Arch. 2018 Jun;472(6):959-968.
Title:	Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Author:	Wang, Yajian\|Liu, Haijing\|Hou, Yingyong\|Zhou, Xiaoyan\|Liang, Li\|Zhang, Zhihong\|Shi, Huaiyin\|Xu, Sanpeng\|Hu, Peizhen\|Zheng, Zuyu\|Liu, Rui\|Tang, Tingdong\|Ye, Feng\|Liang, Zhiyong\|Bu, Hong
PMID:	29705968

329.
Journal:	J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title:	Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Author:	Loree, Jonathan M\|Bailey, Ann M\|Johnson, Amber M\|Yu, Yao\|Wu, Wenhui\|Bristow, Christopher A\|Davis, Jennifer S\|Shaw, Kenna R\|Broaddus, Russell\|Banks, Kimberly C\|Lanman, Richard B\|Meric-Bernstam, Funda\|Overman, Michael J\|Kopetz, Scott\|Raghav, Kanwal
PMID:	29718453

330.
Journal:	Exp Ther Med. 2018 May;15(5):4229-4242.
Title:	Upregulation of c-mesenchymal epithelial transition expression and RAS mutations are associated with late lung metastasis and poor prognosis in colorectal carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Xu, Lishu\|Ma, Dong
PMID:	29725370

331.
Journal:	Pathol Res Pract. 2018 Jun;214(6):826-834.
Title:	Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author:	Tsikalakis, Spyridon\|Chatziandreou, Ilenia\|Michalopoulos, Nikolaos V\|Theodoropoulos, Georgios E\|Sakellariou, Stratigoula\|Korkolopoulou, Penelope\|Patsouris, Efstratios\|Saetta, Angelica A
PMID:	29731264

332.
Journal:	Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title:	Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
Author:	D'Haene, Nicky\|Fontanges, Quitterie\|De Neve, Nancy\|Blanchard, Oriane\|Melendez, Barbara\|Delos, Monique\|Dehou, Marie-Francoise\|Maris, Calliope\|Nagy, Nathalie\|Rousseau, Emmanuel\|Vandenhove, Josse\|Gilles, Andre\|De Prez, Carine\|Verset, Laurine\|Van Craynest, Ma
PMID:	29755687

333.
Journal:	Neoplasma. 2018 Mar 14;65(3):415-424.
Title:	Novel insights into transcriptional dysregulation in colorectal cancer.
Author:	Feodorova, Y\|Tashkova, D\|Koev, I\|Todorov, A\|Kostov, G\|Simitchiev, K\|Belovejdov, V\|Dimov, R\|Sarafian, V
PMID:	29788743

334.
Journal:	Arch Pathol Lab Med. 2018 May 23.
Title:	Colorectal Liver Metastases: A Pathologist's Guide to Creating an Informative Report and Improving Patient Care.
Author:	Moreno Prats, Mariana\|Sasatomi, Eizaburo\|Stevenson, Heather L
PMID:	29790787

335.
Journal:	Clin Transl Oncol. 2018 May 25. pii: 10.1007/s12094-018-1874-8.
Title:	Molecular subtypes in early colorectal cancer associated with clinical features and patient prognosis.
Author:	Gil-Raga, M\|Jantus-Lewintre, E\|Gallach, S\|Giner-Bosch, V\|Frangi-Caregnato, A\|Safont-Aguilera, M J\|Garde-Noguera, J\|Zorraquino-Pina, E\|Garcia-Martinez, M\|Camps-Herrero, C
PMID:	29802524

336.
Journal:	Oncotarget. 2018 May 8;9(35):24081-24096.
Title:	Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Del Carmen, Sofia\|Del Mar Abad, Maria\|Corchete, Luis Antonio\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Baldeon, Maria Jesus\|Cruz, Juan Jesus\|Alcazar, Jose Antonio\|Angoso, Maria\|Gonzalez, Marcos\|Garcia, Jacinto\|Munoz-Bellvis, Luis\|Orfa
PMID:	29844874

337.
Journal:	Oncotarget. 2018 Apr 27;9(32):22749-22768.
Title:	Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
Author:	Oliveira, Duarte Mendes\|Mirante, Teresa\|Mignogna, Chiara\|Scrima, Marianna\|Migliozzi, Simona\|Rocco, Gaetano\|Franco, Renato\|Corcione, Francesco\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29854313

338.
Journal:	Med Oncol. 2018 May 31;35(7):101.
Title:	Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Author:	Papaxoinis, George\|Kotoula, Vassiliki\|Giannoulatou, Eleni\|Koliou, Georgia-Angeliki\|Karavasilis, Vasilios\|Lakis, Sotirios\|Koureas, Andreas\|Bobos, Mattheos\|Chalaralambous, Elpida\|Daskalaki, Emily\|Chatzopoulos, Kyriakos\|Tsironis, George\|Pazarli, Elisavet\|Chr
PMID:	29855806

339.
Journal:	Cancer Sci. 2018 Jun;109(6):2074-2079.
Title:	Japanese Society of Medical Oncology Clinical Guidelines: Molecular Testing for Colorectal Cancer Treatment, Third Edition.
Author:	Yamazaki, Kentaro\|Taniguchi, Hiroya\|Yoshino, Takayuki\|Akagi, Kiwamu\|Ishida, Hideyuki\|Ebi, Hiromichi\|Nakatani, Kaname\|Muro, Kei\|Yatabe, Yasushi\|Yamaguchi, Kensei\|Tsuchihara, Katsuya
PMID:	29873882

340.
Journal:	Cancer Sci. 2018 Aug;109(8):2567-2575.
Title:	Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Mashima, Tetsuo\|Wakatsuki, Takeru\|Suenaga, Mitsukuni\|Ichimura, Takashi\|Ogura, Mariko\|Ota, Yumiko\|Nakayama, Izuma\|Takahari, Daisuke\|Chin, Keisho\|Miki, Yoshio\|Yamaguchi, Kensei
PMID:	29908105

341.
Journal:	Ann Transl Med. 2018 May;6(9):159.
Title:	Colorectal cancer genomics and designing rational trials.
Author:	Mondaca, Sebastian\|Yaeger, Rona
PMID:	29911107

342.
Journal:	Curr Probl Cancer. 2018 May 25. pii: S0147-0272(18)30038-2.
Title:	Common KRAS and NRAS gene mutations in sporadic colorectal cancer in Northeastern Iranian patients.
Author:	Hamzehzadeh, Leila\|Khadangi, Fatemeh\|Ghayoor Karimiani, Ehsan\|Pasdar, Alireza\|Kerachian, Mohammad Amin
PMID:	29921458

343.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

344.
Journal:	J Mol Diagn. 2018 Sep;20(5):664-676.
Title:	Multicenter Evaluation of the Idylla NRAS-BRAF Mutation Test in Metastatic Colorectal Cancer.
Author:	Prieto-Potin, Ivan\|Montagut, Clara\|Bellosillo, Beatriz\|Evans, Matthew\|Smith, Matthew\|Melchior, Linea\|Reiltin, Werner\|Bennett, Michael\|Pennati, Veronica\|Castiglione, Francesca\|Burrig, Karl-Friedrich\|Cooper, Ulrike\|Dockhorn-Dworniczak, Barbara\|Rossenbach, C
PMID:	29959022

345.
Journal:	World J Surg Oncol. 2018 Jul 5;16(1):128.
Title:	Differences in gene mutations according to gender among patients with colorectal cancer.
Author:	Tsai, Yi-Jian\|Huang, Sheng-Chieh\|Lin, Hung-Hsin\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Chen, Wei-Shone\|Lin, Tzu-Chen\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	29976257

346.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Jul 5.
Title:	Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
Author:	Wedden, Sarah\|Miller, Keith\|Frayling, Ian M\|Thomas, Teresa\|Chefani, Alina\|Miller, Karolina\|Hamblin, Angela\|Taylor, Jenny C\|D'Arrigo, Corrado
PMID:	29985199

347.
Journal:	Cancer Res. 2018 Sep 1;78(17):5164-5172.
Title:	A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer.
Author:	Chang, Jiang\|Tian, Jianbo\|Yang, Yang\|Zhong, Rong\|Li, Jiaoyuan\|Zhai, Kan\|Ke, Juntao\|Lou, Jiao\|Chen, Wei\|Zhu, Beibei\|Shen, Na\|Zhang, Yi\|Gong, Yajie\|Zhu, Ying\|Zou, Danyi\|Peng, Xiating\|Huang, Kun\|Miao, Xiaoping
PMID:	30026326

348.
Journal:	BMC Cancer. 2018 Jul 20;18(1):752.
Title:	Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.
Author:	Mogensen, M B\|Rossing, M\|Ostrup, O\|Larsen, P N\|Heiberg Engel, P J\|Jorgensen, L N\|Hogdall, E V\|Eriksen, J\|Ibsen, P\|Jess, P\|Grauslund, M\|Nielsen, H J\|Nielsen, F C\|Vainer, B\|Osterlind, K
PMID:	30029640

349.
Journal:	Cancer Biol Ther. 2018 Jul 23:1-4.
Title:	Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations.
Author:	Ofir Dovrat, Tali\|Sokol, Ethan\|Frampton, Garrett\|Shachar, Eliya\|Pelles, Sharon\|Geva, Ravit\|Wolf, Ido
PMID:	30036146

350.
Journal:	Mol Cancer. 2018 Jul 23;17(1):102.
Title:	RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.
Author:	Pan, Yi\|Tong, Joanna Hung Man\|Lung, Raymond Wai Ming\|Kang, Wei\|Kwan, Johnny Sheung Him\|Chak, Wing Po\|Tin, Ka Yee\|Chung, Lau Ying\|Wu, Feng\|Ng, Simon Siu Man\|Mak, Tony Wing Chung\|Yu, Jun\|Lo, Kwok Wai\|Chan, Anthony Wing Hung\|To, Ka Fai
PMID:	30037330

351.
Journal:	Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title:	Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author:	Domingo, Enric\|Camps, Carme\|Kaisaki, Pamela J\|Parsons, Marie J\|Mouradov, Dmitri\|Pentony, Melissa M\|Makino, Seiko\|Palmieri, Michelle\|Ward, Robyn L\|Hawkins, Nicholas J\|Gibbs, Peter\|Askautrud, Hanne\|Oukrif, Dahmane\|Wang, Haitao\|Wood, Joe\|Tomlinson, Evie\|Bark
PMID:	30042065

352.
Journal:	Adv Clin Exp Med. 2018 Aug 7.
Title:	Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Author:	Wojas-Krawczyk, Kamila\|Kalinka-Warzocha, Ewa\|Reszka, Katarzyna\|Nicos, Marcin\|Szumilo, Justyna\|Mandziuk, Slawomir\|Szczepaniak, Katarzyna\|Kupnicka, Dorota\|Lewandowski, Remigiusz\|Milanowski, Janusz\|Krawczyk, Pawel
PMID:	30085422

353.
Journal:	Digestion. 2018 Aug 21;98(4):263-269.
Title:	Anti-EGF Receptor-Based Conversion Chemotherapy in RAS Wild-Type Colorectal Cancer Patients: Impact on Survival and Resection Rates.
Author:	Koch, Christine\|Schmidt, Niklas\|Winkelmann, Ria\|Eichler, Katrin\|Pession, Ursula\|Bechstein, Wolf Otto\|Zeuzem, Stefan\|Waidmann, Oliver\|Trojan, Jorg
PMID:	30130797

354.
Journal:	Contemp Oncol (Pozn). 2018;22(2):75-85.
Title:	Quality and practical aspects of pathological and molecular diagnostics in metastatic colorectal cancer (mCRC).
Author:	Tysarowski, Andrzej\|Nasierowska-Guttmejer, Anna
PMID:	30150883

355.
Journal:	J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title:	The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author:	Zou, Shuang-Mei\|Li, Wei-Hua\|Wang, Wen-Miao\|Li, Wen-Bin\|Shi, Su-Sheng\|Ying, Jian-Ming\|Lyu, Ning
PMID:	30171333

356.
Journal:	Cancer Cell Int. 2018 Sep 6;18:131.
Title:	Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author:	Fassan, Matteo\|Vianello, Luca\|Sacchi, Diana\|Fanelli, Giuseppe N\|Munari, Giada\|Scarpa, Marco\|Cappellesso, Rocco\|Loupakis, Fotios\|Lanza, Cristiano\|Salmaso, Roberta\|Mescoli, Claudia\|Valeri, Nicola\|Agostini, Marco\|D'Angelo, Edoardo\|Lonardi, Sara\|Pucciarelli,
PMID:	30202242

357.
Journal:	Clin Colorectal Cancer. 2018 Jul 17. pii: S1533-0028(18)30133-6.
Title:	Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Author:	Khan, Maliha\|Loree, Jonathan M\|Advani, Shailesh M\|Ning, Jing\|Li, Wen\|Pereira, Allan A L\|Lam, Michael\|Raghav, Kanwal\|Morris, Van K\|Broaddus, Russell\|Maru, Dipen\|Overman, Michael J\|Kopetz, Scott
PMID:	30205948

358.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):978-997.
Title:	Liquid Biopsy to Identify Actionable Genomic Alterations.
Author:	Ou, Sai-Hong Ignatius\|Nagasaka, Misako\|Zhu, Viola W
PMID:	30231331

359.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):231-238.
Title:	Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	30231342

360.
Journal:	Int J Cancer. 2018 Sep 25.
Title:	Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
Author:	Bormann, Felix\|Stinzing, Sebastian\|Tierling, Sascha\|Morkel, Markus\|Rivera Markelova, Maria\|Walter, Jorn\|Weichert, Wilko\|Rossner, Florian\|Kuhn, Natalia\|Perner, Juliane\|Dietz, Johanna\|Ispasanie, Sylvia\|Dietel, Manfred\|Schafer, Reinhold\|Heinemann, Volker\|Ser
PMID:	30252132

361.
Journal:	Orv Hetil. 2018 Oct;159(40):1614-1623.
Title:	[Colorectal cancer susceptibility genetic variants in tumor free and colorectal carcinoma bearing Hungarian population. Individual predisposition to cancer].
Author:	Szentirmay, Zoltan\|Kurcsics, Judit\|Csernak, Erzsebet\|Tandor, Ildiko\|Toth, Erika
PMID:	30277414

362.
Journal:	Ann Oncol. 2018 Oct 18. pii: 5136414.
Title:	Biomarker analysis beyond angiogenesis: RAS/RAF mutation status, tumour sidedness, and second-line ramucirumab efficacy in patients with metastatic colorectal carcinoma from RAISE, a global phase 3 study.
Author:	Yoshino, T\|Portnoy, D C\|Obermannova, R\|Bodoky, G\|Prausova, J\|Garcia-Carbonero, R\|Ciuleanu, T\|Garcia-Alfonso, P\|Cohn, A L\|Van Cutsem, E\|Yamazaki, K\|Lonardi, S\|Muro, K\|Kim, T W\|Yamaguchi, K\|Grothey, A\|O'Connor, J\|Taieb, J\|Wijayawardana, S R\|Hozak, R R\|Nasro
PMID:	30339194

363.
Journal:	Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title:	Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author:	Del Carmen, Sofia\|Sayagues, Jose Maria\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Alcazar, Jose Antonio\|Gervas, Ruth\|Garcia, Jacinto\|Orfao, Alberto\|Bellvis, Luis Munoz\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria
PMID:	30344942