Primary Site >> Liver Cancer

Gene >> NOTCH2

Journal: Zhonghua Zhong Liu Za Zhi. 1991 Sep;13(5):325-7.
Title: [Unscheduled DNA synthesis of peripheral blood lymphocytes in pedigrees of hepatocellular carcinoma patients].
Author: Wang, J B
PMID: 1664315
Journal: Cancer Chemother Pharmacol. 2001;47(2):149-54.
Title: Treatment of VX2 carcinoma implanted in the liver with arterial and intraperitoneal administration of oily anticancer agents.
Author: Tabaru, K|Konno, T|Oda, T|Nagamitsu, A|Ishimaru, Y|Kitamura, N
PMID: 11269741
Journal: Dig Liver Dis. 2008 Feb;40(2):114-21.
Title: Deregulated expression of Notch receptors in human hepatocellular carcinoma.
Author: Gao, J|Song, Z|Chen, Y|Xia, L|Wang, J|Fan, R|Du, R|Zhang, F|Hong, L|Song, J|Zou, X|Xu, H|Zheng, G|Liu, J|Fan, D
PMID: 17920003
Journal: Arch Toxicol. 2013 Jun;87(6):1001-12.
Title: Inhibition of hepatocyte nuclear factor 1 and 4 alpha (HNF1alpha and HNF4alpha) as a mechanism of arsenic carcinogenesis.
Author: Pastoret, Anna|Marcos, Ricard|Sampayo-Reyes, Adriana|Saucedo-Cardenas, Odila|Lozano-Garza, Gerardo H|Hernandez, Alba
PMID: 23052196
Journal: Hepatology. 2013 Apr;57(4):1607-19.
Title: Constitutive Notch2 signaling induces hepatic tumors in mice.
Author: Dill, Michael T|Tornillo, Luigi|Fritzius, Thorsten|Terracciano, Luigi|Semela, David|Bettler, Bernhard|Heim, Markus H|Tchorz, Jan S
PMID: 23175466
Journal: Lipids Health Dis. 2013 Dec 17;12:186.
Title: Microarray analysis provides new insights into the function of apolipoprotein O in HepG2 cell line.
Author: Wu, Chen-Lu|Zhao, Shui-Ping|Yu, Bi-Lian
PMID: 24341743
Journal: Gut. 2014 Apr;63(4):674-85.
Title: Keratin 19: a key role player in the invasion of human hepatocellular carcinomas.
Author: Govaere, Olivier|Komuta, Mina|Berkers, Johannes|Spee, Bart|Janssen, Carl|de Luca, Francesca|Katoonizadeh, Aezam|Wouters, Jasper|van Kempen, Leon C|Durnez, Anne|Verslype, Chris|De Kock, Joery|Rogiers, Vera|van Grunsven, Leo A|Topal, Baki|Pirenne, Jacques|V
PMID: 23958557
Journal: J Hepatol. 2014 Oct;61(4):832-9.
Title: The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Xu, Bin|Ding, Li-Hong|Zheng, Qi-Lin|Zhang, Li|Zheng, Qi-Fan|Li, Shan-Hua|Feng, Zi-Jie|Wei, Jie|Yin, Zhen-Yu|Hua, Xianxin|Jin, Guang-Hui
PMID: 24845612
Journal: Mol Cancer Res. 2014 Oct;12(10):1388-97.
Title: EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Zheng, Qi-Fan|Xu, Bin|Pan, Chang-Bao|Li, Kang-Li|Zhao, Yue|Zheng, Qi-Lin|Lin, Xiao|Xue, Li-Xiang|Jin, Guang-Hui
PMID: 24916103
Journal: Int J Clin Exp Pathol. 2014 May 15;7(6):3272-9. eCollection 2014.
Title: Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.
Author: Wu, Wen-Rui|Shi, Xiang-De|Zhang, Rui|Zhu, Man-Sheng|Xu, Lei-Bo|Yu, Xian-Huan|Zeng, Hong|Wang, Jie|Liu, Chao
PMID: 25031748
Journal: Zhonghua Gan Zang Bing Za Zhi. 2014 May;22(5):354-7.
Title: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells].
Author: Li, Jianfang|Ding, Shixiong|Ying, Liping|Hu, Airong|Hu, Yaoren|Liang, Xiaoyue
PMID: 25180870
Journal: Hepatology. 2015 Mar;61(3):942-52.
Title: Differential effects of targeting Notch receptors in a mouse model of liver cancer.
Author: Huntzicker, Erik G|Hotzel, Kathy|Choy, Lisa|Che, Li|Ross, Jed|Pau, Gregoire|Sharma, Neeraj|Siebel, Christian W|Chen, Xin|French, Dorothy M
PMID: 25311838
Journal: Cancer Res. 2015 May 1;75(9):1859-67.
Title: miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells.
Author: Zhang, Jing|Jiao, Jingjing|Cermelli, Silvia|Muir, Kyle|Jung, Kwang Hwa|Zou, Ruhai|Rashid, Asif|Gagea, Mihai|Zabludoff, Sonya|Kalluri, Raghu|Beretta, Laura
PMID: 25769721
Journal: Nat Commun. 2015 May 19;6:7122.
Title: C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.
Author: Zhu, Pingping|Wang, Yanying|Du, Ying|He, Lei|Huang, Guanling|Zhang, Geng|Yan, Xinlong|Fan, Zusen
PMID: 25985737
Journal: Oncol Rep. 2015 Oct;34(4):1650-8.
Title: NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells.
Author: Hayashi, Yoshihiro|Osanai, Makoto|Lee, Gang-Hong
PMID: 26252838
Journal: Oncol Rep. 2016 Jul;36(1):181-8.
Title: Notch2 is a crucial regulator of self-renewal and tumorigenicity in human hepatocellular carcinoma cells.
Author: Wu, Wen-Rui|Zhang, Rui|Shi, Xiang-De|Yi, Cao|Xu, Lei-Bo|Liu, Chao
PMID: 27221981
Journal: Oncol Rep. 2017 Jan;37(1):348-356.
Title: Hepatitis B virus X protein and hypoxiainducible factor-1alpha stimulate Notch gene expression in liver cancer cells.
Author: Yang, Sheng-Li|Ren, Quan-Guang|Zhang, Tao|Pan, Xiaoli|Wen, Lu|Hu, Jian-Li|Yu, Chao|He, Qian-Jin
PMID: 27840976
Journal: Appl Immunohistochem Mol Morphol. 2017 Feb 9.
Title: A Brief Report of Immunohistochemical Markers to Identify Aggressive Hepatoblastoma.
Author: Singh, Vivekanand|Manalang, Michelle|Singh, Meenal|Apte, Udayan
PMID: 28187036
Journal: J Egypt Natl Canc Inst. 2017 Mar;29(1):19-24.
Title: Gene expression profiling of circulating CD133(+) cells of hepatocellular carcinoma patients associated with HCV infection.
Author: Zekri, Abdel-Rahman N|El-Sisi, Enas R|Abdallah, Zeinab F|Ismail, Alaa|Barakat Barakat, Ahmed
PMID: 28258914
Journal: Cancer Res. 2017 May 1;77(9):2255-2265.
Title: Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma.
Author: Lin, De-Chen|Mayakonda, Anand|Dinh, Huy Q|Huang, Pinbo|Lin, Lehang|Liu, Xiaoping|Ding, Ling-Wen|Wang, Jie|Berman, Benjamin P|Song, Er-Wei|Yin, Dong|Koeffler, H Phillip
PMID: 28302680
Journal: Cell Death Differ. 2017 May;24(5):889-902.
Title: Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.
Author: Gnani, Daniela|Romito, Ilaria|Artuso, Simona|Chierici, Marco|De Stefanis, Cristiano|Panera, Nadia|Crudele, Annalisa|Ceccarelli, Sara|Carcarino, Elena|D'Oria, Valentina|Porru, Manuela|Giorda, Ezio|Ferrari, Karin|Miele, Luca|Villa, Erica|Balsano, Clara|Pasi
PMID: 28338656
Journal: Front Immunol. 2017 Mar 22;8:320.
Title: 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8(+) T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model.
Author: Dai, Kai|Huang, Ling|Huang, Ya-Bing|Chen, Zu-Bing|Yang, Li-Hua|Jiang, Ying-An
PMID: 28382040
Journal: Front Pharmacol. 2017 Jul 7;8:319.
Title: Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model.
Author: Hubmann, Rainer|Sieghart, Wolfgang|Schnabl, Susanne|Araghi, Mohammad|Hilgarth, Martin|Reiter, Marlies|Demirtas, Dita|Valent, Peter|Zielinski, Christoph|Jager, Ulrich|Shehata, Medhat
PMID: 28736522
Journal: Am J Pathol. 2018 Apr;188(4):995-1006.
Title: Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans.
Author: Zhang, Shanshan|Wang, Jingxiao|Wang, Haichuan|Fan, Lingling|Fan, Biao|Zeng, Billy|Tao, Junyan|Li, Xiaolei|Che, Li|Cigliano, Antonio|Ribback, Silvia|Dombrowski, Frank|Chen, Bin|Cong, Wenming|Wei, Lixin|Calvisi, Diego F|Chen, Xin
PMID: 29378174
Journal: Pediatr Dev Pathol. 2018 Mar 8:1093526618762550.
Title: Hepatic Adenoma Arising in a Patient With Alagille Syndrome: A Case Report.
Author: Pacheco, M Cristina|Monroe, Eric J|Horslen, Simon P
PMID: 29516774
Journal: Oncogene. 2018 Jun;37(24):3229-3242.
Title: Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
Author: Wang, Jingxiao|Dong, Mingjie|Xu, Zhong|Song, Xinhua|Zhang, Shanshan|Qiao, Yu|Che, Li|Gordan, John|Hu, Kaiwen|Liu, Yan|Calvisi, Diego F|Chen, Xin
PMID: 29545603
Journal: Cell Death Dis. 2018 May 1;9(5):487.
Title: lncAKHE enhances cell growth and migration in hepatocellular carcinoma via activation of NOTCH2 signaling.
Author: Huang, Guanqun|Jiang, Hui|Lin, Ye|Wu, Yanpeng|Cai, Weilong|Shi, Boyun|Luo, Yuanwei|Jian, Zhixiang|Zhou, Xinke
PMID: 29706630
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: BMC Cancer. 2018 Jun 7;18(1):640.
Title: Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature.
Author: Gronhoj, Christian|Jensen, David H|Agander, Tina|Kiss, Katalin|Hogdall, Estrid|Specht, Lena|Bagger, Frederik Otzen|Nielsen, Finn Cilius|von Buchwald, Christian
PMID: 29879932
Journal: Oncol Rep. 2018 Sep;40(3):1515-1524.
Title: Combined antitumor effects of 1,25dihydroxy vitamin D3 and Notch inhibitor in liver cancer.
Author: Cai, Lijing|Luo, Lifang|Tang, Zhimou|Meng, Xiaohui
PMID: 30015939