Primary Site >> Colorectal Cancer

Gene >> NOTCH2

Journal: Cancer Clin Trials. 1978 Winter;1(4):273-87.
Title: Analysis of adjuvant therapy in large bowel cancer.
Author: Davis, H L|Kisner, D L
PMID: 391429
Journal: J Am Acad Dermatol. 1989 Mar;20(3):416-28.
Title: Long-term efficacy, curative potential, and carcinogenicity of topical mechlorethamine chemotherapy in cutaneous T cell lymphoma.
Author: Vonderheid, E C|Tan, E T|Kantor, A F|Shrager, L|Micaily, B|Van Scott, E J
PMID: 2537348
Journal: Oncogene. 1997 May 8;14(18):2127-36.
Title: Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard.
Author: Fan, S|Chang, J K|Smith, M L|Duba, D|Fornace, A J Jr|O'Connor, P M
PMID: 9174048
Journal: Br J Cancer. 1998 May;77(9):1395-404.
Title: Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells.
Author: Boddie, A W Jr|Constantinou, A|Williams, C|Reed, A
PMID: 9652754
Journal: Proteomics. 2004 Aug;4(8):2261-9.
Title: Radioresistance-related proteins in rectal cancer.
Author: Allal, Abdelkarim S|Kahne, Thilo|Reverdin, Alexandra K|Lippert, Hans|Schlegel, Werner|Reymond, Marc-Andre
PMID: 15274120
Journal: J Cell Biochem. 2005 May 15;95(2):339-51.
Title: Overexpression of GSTA2 protects against cell cycle arrest and apoptosis induced by the DNA inter-strand crosslinking nitrogen mustard, mechlorethamine.
Author: Xie, Jingping|Shults, Keith|Flye, Leanne|Jiang, Fen|Head, David R|Briggs, Robert C
PMID: 15778998
Journal: Int J Oncol. 2007 Jan;30(1):247-51.
Title: Notch signaling in gastrointestinal tract (review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17143535
Journal: Ann Surg Oncol. 2009 Dec;16(12):3259-66.
Title: Notch2 expression is decreased in colorectal cancer and related to tumor differentiation status.
Author: Chu, Dake|Zheng, Jianyong|Wang, Weizhong|Zhao, Qingchuan|Li, Yunming|Li, Jipeng|Xie, Huahong|Zhang, Hongwei|Dong, Guanglong|Xu, Chunsheng|Li, Mengbin|Chen, Dongli|Ji, Gang
PMID: 19653042
Journal: Oncogene. 2010 Feb 18;29(7):992-1002.
Title: Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.
Author: Guilmeau, S|Flandez, M|Mariadason, J M|Augenlicht, L H
PMID: 19935714
Journal: PLoS One. 2011 Mar 18;6(3):e17957.
Title: The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells.
Author: Ungerback, Jonas|Elander, Nils|Grunberg, John|Sigvardsson, Mikael|Soderkvist, Peter
PMID: 21437251
Journal: Int J Stem Cells. 2011 Jun;4(1):70-5.
Title: Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells.
Author: Pinney, Emmett|Zimber, Michael|Schenone, Aaron|Montes-Camacho, Mayra|Ziegler, Frank|Naughton, Gail K
PMID: 24298336
Journal: Genome Biol. 2011 Oct 19;12(10):R103.
Title: Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.
Author: Kloosterman, Wigard P|Hoogstraat, Marlous|Paling, Oscar|Tavakoli-Yaraki, Masoumeh|Renkens, Ivo|Vermaat, Joost S|van Roosmalen, Markus J|van Lieshout, Stef|Nijman, Isaac J|Roessingh, Wijnand|van 't Slot, Ruben|van de Belt, Jose|Guryev, Victor|Koudijs, Marc
PMID: 22014273
Journal: Ann Oncol. 2011 Nov;22(11):2533-4; author reply 2534.
Title: Notch1 and Notch2 have opposite prognostic effects on patients with colorectal cancer.
Author: Masuda, S
PMID: 21709139
Journal: Ann Oncol. 2011 Nov;22(11):2440-7.
Title: Notch1 and Notch2 have opposite prognostic effects on patients with colorectal cancer.
Author: Chu, D|Zhang, Z|Zhou, Y|Wang, W|Li, Y|Zhang, H|Dong, G|Zhao, Q|Ji, G
PMID: 21378202
Journal: Tumour Biol. 2012 Jun;33(3):817-24.
Title: Expression and clinical significance of Notch signaling genes in colorectal cancer.
Author: Jin, Hei-Ying|Zhang, Hong-Ying|Wang, Xiaofeng|Xu, Junhua|Ding, Yijing
PMID: 22219033
Journal: Biochem Pharmacol. 2012 May 1;83(9):1172-82.
Title: Increased expression of VDAC1 sensitizes carcinoma cells to apoptosis induced by DNA cross-linking agents.
Author: Sharaf el dein, Ossama|Gallerne, Cindy|Brenner, Catherine|Lemaire, Christophe
PMID: 22285227
Journal: PLoS One. 2012;7(8):e41001.
Title: Transcriptome profiling of the cancer, adjacent non-tumor and distant normal tissues from a colorectal cancer patient by deep sequencing.
Author: Wu, Yan'an|Wang, Xuetao|Wu, Fangbo|Huang, Ruolei|Xue, Fangqin|Liang, Guantao|Tao, Min|Cai, Pengwei|Huang, Yi
PMID: 22905095
Journal: Pathol Discov. 2013 Aug 16;1:4.
Title: NOTCH2 expression is decreased in epithelial ovarian cancer and is related to the tumor histological subtype.
Author: Galic, Vijaya|Shawber, Carrie J|Reeves, Claire|Shah, Monjri|Murtomaki, Aino|Wright, Jason|Herzog, Thomas|Tong, Guo Xia|Kitajewski, Jan
PMID: 24707357
Journal: Dis Markers. 2013;35(5):395-405.
Title: Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients.
Author: Wang, Wen-Juan|Yao, Yu|Jiang, Li-Li|Hu, Ting-Hua|Ma, Jie-Qun|Ruan, Zhi-Ping|Tian, Tao|Guo, Hui|Wang, Shu-Hong|Nan, Ke-Jun
PMID: 24223455
Journal: Onco Targets Ther. 2013;6:145-53.
Title: Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling.
Author: Jin, Heiying|Gong, Wei|Zhang, Chunxia|Wang, Shuiming
PMID: 23525843
Journal: Pharmacogenomics J. 2014 Apr;14(2):142-50.
Title: Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence.
Author: Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J
PMID: 23817222
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1687-97.
Title: A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Author: Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin
PMID: 24470513
Journal: Cancer Res. 2014 Apr 1;74(7):2106-18.
Title: NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.
Author: Pasto, Anna|Serafin, Valentina|Pilotto, Giorgia|Lago, Claudia|Bellio, Chiara|Trusolino, Livio|Bertotti, Andrea|Hoey, Timothy|Plateroti, Michelina|Esposito, Giovanni|Pinazza, Marica|Agostini, Marco|Nitti, Donato|Amadori, Alberto|Indraccolo, Stefano
PMID: 24525742
Journal: Zhonghua Gan Zang Bing Za Zhi. 2014 May;22(5):354-7.
Title: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells].
Author: Li, Jianfang|Ding, Shixiong|Ying, Liping|Hu, Airong|Hu, Yaoren|Liang, Xiaoyue
PMID: 25180870
Journal: Int J Mol Med. 2016 Sep;38(3):776-84.
Title: Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.
Author: Suliman, Mohammed A|Zhang, Zhenxing|Na, Heya|Ribeiro, Ailton L L|Zhang, Yu|Niang, Bachir|Hamid, Abdu Salim|Zhang, Hua|Xu, Lijie|Zuo, Yunfei
PMID: 27460529
Journal: BMC Med Genomics. 2016 Sep 8;9(1):58.
Title: A 19-Gene expression signature as a predictor of survival in colorectal cancer.
Author: Abdul Aziz, Nurul Ainin|Mokhtar, Norfilza M|Harun, Roslan|Mollah, Md Manir Hossain|Mohamed Rose, Isa|Sagap, Ismail|Mohd Tamil, Azmi|Wan Ngah, Wan Zurinah|Jamal, Rahman
PMID: 27609023
Journal: Oncotarget. 2017 Jul 11;8(28):46081-46089.
Title: Killing effects of Huaier Granule combined with DC-CIK on nude mice transplanted with colon carcinoma cell line.
Author: Sun, Wen-Wen|Dou, Jin-Xia|Zhang, Lin|Qiao, Li-Kui|Shen, Na|Zhao, Qiang|Gao, Wen-Yuan
PMID: 28537906
Journal: Tumour Biol. 2017 Jul;39(7):1010428317708699.
Title: Portulaca oleracea extract can inhibit nodule formation of colon cancer stem cells by regulating gene expression of the Notch signal transduction pathway.
Author: Jin, Heiying|Chen, Li|Wang, Shuiming|Chao, Deng
PMID: 28714363
Journal: Oncol Rep. 2017 Sep;38(3):1895-1901.
Title: Spica Prunellae extract suppresses the growth of human colon carcinoma cells by targeting multiple oncogenes via activating miR-34a.
Author: Fang, Yi|Zhang, Ling|Feng, Jianyu|Lin, Wei|Cai, Qiaoyan|Peng, Jun
PMID: 28713966
Journal: Exp Cell Res. 2017 Mar 1;352(1):104-112.
Title: miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT.
Author: Chen, Jia|Zhang, Haichen|Chen, Ying|Qiao, Guanglei|Jiang, Weihua|Ni, Peihua|Liu, Xiangfan|Ma, Lijun
PMID: 28161537
Journal: Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):168-173.
Title: [Killing effect of Huaier combined with DC-CIK on nude mice bearing colon cancer HT29 stem cells in vivo].
Author: Sun, Wen-Wen|Dou, Jin-Xia|Zhang, Lin|Qiao, Li-Kui|Shen, Na|Gao, Wen-Yuan
PMID: 29552828
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Int J Biol Macromol. 2018 Oct 1;117:445-453.
Title: Overcoming stemness and chemoresistance in colorectal cancer through miR-195-5p-modulated inhibition of notch signaling.
Author: Jin, Yinghu|Wang, Meng|Hu, Hanqing|Huang, Quanlong|Chen, Yinggang|Wang, Guiyu
PMID: 29852230
Journal: Sci Rep. 2018 Jun 13;8(1):9032.
Title: Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.
Author: Chattopadhyay, Arnab|Yang, Xinying|Mukherjee, Pallavi|Sulaiman, Dawoud|Fogelman, Hannah R|Grijalva, Victor|Dubinett, Steven|Wasler, Tonya C|Paul, Manash K|Salehi-Rad, Ramin|Mack, Julia J|Iruela-Arispe, M Luisa|Navab, Mohamad|Fogelman, Alan M|Reddy, Sriniv
PMID: 29899427
Journal: Mol Med Rep. 2018 Oct 17.
Title: Identification of recurrent and novel mutations by wholegenome sequencing of colorectal tumors from the Han population in Shanghai, eastern China.
Author: Teng, Hongfei|Gao, Renyuan|Qin, Nan|Jiang, Xun|Ren, Min|Wang, Yu|Wu, Shouxin|Li, Ning|Zhao, Jiangman|Qin, Huanlong
PMID: 30365144
Journal: Cancers (Basel). 2018 Oct 30;10(11). pii: cancers10110411.
Title: POFUT1 as a Promising Novel Biomarker of Colorectal Cancer.
Author: Chabanais, Julien|Labrousse, Francois|Chaunavel, Alain|Germot, Agnes|Maftah, Abderrahman
PMID: 30380753