Primary Site >> Pancreatic Cancer

Gene >> NOS2

Journal: Langenbecks Arch Surg. 1998 Dec;383(6):474-80.
Title: Overexpression of endothelium-derived nitric oxide synthase isoform 3 in the vasculature of human pancreatic tumor biopsies.
Author: Nussler, A K|Gansauge, S|Gansauge, F|Fischer, U|Butzer, U|Kremsner, P G|Beger, H G
PMID: 9921950
Journal: Arch Surg. 1999 Mar;134(3):245-51.
Title: Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer.
Author: Vickers, S M|MacMillan-Crow, L A|Green, M|Ellis, C|Thompson, J A
PMID: 10088562
Journal: J Leukoc Biol. 1999 May;65(5):597-604.
Title: Demonstration of iNOS-mRNA and iNOS in human monocytes stimulated with cancer cells in vitro.
Author: Siedlar, M|Mytar, B|Krzeszowiak, A|Baran, J|Hyszko, M|Ruggiero, I|Wieckiewicz, J|Stachura, J|Zembala, M
PMID: 10331487
Journal: Cancer Res. 2000 Jan 1;60(1):2-7.
Title: Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages.
Author: Bruns, C J|Shinohara, H|Harbison, M T|Davis, D W|Nelkin, G|Killion, J J|McConkey, D J|Dong, Z|Fidler, I J
PMID: 10646841
Journal: J Interferon Cytokine Res. 2001 Jul;21(7):529-37.
Title: Regulation of interleukin-8 expression by nitric oxide in human pancreatic adenocarcinoma.
Author: Xiong, Q|Shi, Q|Le, X|Wang, B|Xie, K
PMID: 11506748
Journal: Int J Pancreatol. 2001;29(3):133-40.
Title: Inducible nitric oxide synthase (iNOS) immunoreactivity and its relationship to cell proliferation, apoptosis, angiogenesis, clinicopathologic characteristics, and patient survival in pancreatic cancer.
Author: Kong, G|Kim, E K|Kim, W S|Lee, Y W|Lee, J K|Paik, S W|Rhee, J C|Choi, K W|Lee, K T
PMID: 12067216
Journal: Int J Gastrointest Cancer. 2001;29(3):133-140.
Title: Inducible Nitric Oxide Synthase (iNOS) Immunoreactivity and Its Relationship to Cell Proliferation, Apoptosis, Angiogenesis, Clinicopathologic Characteristics, and Patient Survival in Pancreatic Cancer.
Author: Kong, Gu|Kim, Eun|Kim, Wan|Lee, Yong|Lee, Jong|Paik, Seung|Rhee, Jong|Choi, Kyoo|Lee, Kyu
PMID: 12754383
Journal: J Gastroenterol Hepatol. 2002 Aug;17(8):914-21.
Title: Role of cyclooxygenase-2 and inducible nitric oxide synthase in pancreatic cancer.
Author: Kong, Gu|Kim, Eun Kyung|Kim, Wan Sup|Lee, Kyu Taek|Lee, Yong Wook|Lee, Jong Kyun|Paik, Seung Woon|Rhee, Jong Chul
PMID: 12164968
Journal: Oncogene. 2003 Mar 27;22(12):1771-82.
Title: A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis.
Author: Wang, Bailiang|Wei, Daoyan|Crum, Vanessa E|Richardson, Erica L|Xiong, Henry H|Luo, Yu|Huang, Suyun|Abbruzzese, James L|Xie, Keping
PMID: 12660813
Journal: Cancer Res. 2004 Feb 15;64(4):1331-7.
Title: Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta.
Author: Muerkoster, Susanne|Wegehenkel, Kai|Arlt, Alexander|Witt, Maike|Sipos, Bence|Kruse, Marie-Luise|Sebens, Thorsten|Kloppel, Gunter|Kalthoff, Holger|Folsch, Ulrich R|Schafer, Heiner
PMID: 14973050
Journal: Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):51-8.
Title: Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic cancer.
Author: Franco, Luigina|Doria, Denise|Bertazzoni, Elisa|Benini, Anna|Bassi, Claudio
PMID: 15165031
Journal: World J Gastroenterol. 2004 Jul 1;10(13):1918-22.
Title: Expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic adenocarcinoma: correlation with microvessel density.
Author: Kasper, Hans-U|Wolf, Hella|Drebber, Uta|Wolf, Helmut-K|Kern, Michael-A
PMID: 15222037
Journal: Clin Cancer Res. 2006 Apr 15;12(8):2628-33.
Title: Roles of nitric oxide synthase inhibition and vascular endothelial growth factor receptor-2 inhibition on vascular morphology and function in an in vivo model of pancreatic cancer.
Author: Camp, E Ramsay|Yang, Anthony|Liu, Wenbiao|Fan, Fan|Somcio, Ray|Hicklin, Daniel J|Ellis, Lee M
PMID: 16638876
Journal: Carcinogenesis. 2008 Aug;29(8):1608-13.
Title: Increased expression of inducible nitric oxide synthase (iNOS) in N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis and prevention of cancer development by ONO-1714, an iNOS inhibitor.
Author: Takahashi, Mami|Kitahashi, Tsukasa|Ishigamori, Rikako|Mutoh, Michihiro|Komiya, Masami|Sato, Hidetaka|Kamanaka, Yoshihisa|Naka, Masao|Maruyama, Takayuki|Sugimura, Takashi|Wakabayashi, Keiji
PMID: 18567618
Journal: Nutr Cancer. 2008;60 Suppl 1:81-9.
Title: Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids.
Author: Swamy, Malisetty V|Citineni, Bhargava|Patlolla, Jagan M R|Mohammed, Altaf|Zhang, Yuting|Rao, Chinthalapally V
PMID: 19003584
Journal: Semin Immunopathol. 2013 Mar;35(2):203-27.
Title: Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.
Author: Takahashi, Mami|Mutoh, Michihiro|Ishigamori, Rikako|Fujii, Gen|Imai, Toshio
PMID: 22955327
Journal: FEBS Lett. 2014 Aug 25;588(17):3240-50.
Title: Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation.
Author: Fujita, Mayumi|Imadome, Kaori|Endo, Satoshi|Shoji, Yoshimi|Yamada, Shigeru|Imai, Takashi
PMID: 25019574
Journal: Pathol Res Pract. 2014 Dec;210(12):901-8.
Title: Serous neoplasms of the pancreas share many, but not all aspects of their microvascular and angiogenic profile with low-grade clear cell renal cell carcinomas.
Author: Liszka, Lukasz|Pajak, Jacek|Golka, Dariusz
PMID: 25155377
Journal: IUBMB Life. 2014 Dec;66(12):835-46.
Title: Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages.
Author: Meng, Fanbin|Li, Changling|Li, Wan|Gao, Zhigang|Guo, Kejian|Song, Shaowei
PMID: 25557640
Journal: Clin Cancer Res. 2015 Apr 1;21(7):1741-51.
Title: Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.
Author: O'Leary, Brianne R|Fath, Melissa A|Bellizzi, Andrew M|Hrabe, Jennifer E|Button, Anna M|Allen, Bryan G|Case, Adam J|Altekruse, Sean|Wagner, Brett A|Buettner, Garry R|Lynch, Charles F|Hernandez, Brenda Y|Cozen, Wendy|Beardsley, Robert A|Keene, Jeffery|Henry
PMID: 25634994
Journal: Oncotarget. 2016 Aug 16;7(33):52993-53004.
Title: Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer.
Author: Wang, Jian|He, Peijun|Gaida, Matthias|Yang, Shouhui|Schetter, Aaron J|Gaedcke, Jochen|Ghadimi, B Michael|Ried, Thomas|Yfantis, Harris|Lee, Dong|Weiss, Jonathan M|Stauffer, Jimmy|Hanna, Nader|Alexander, H Richard|Hussain, S Perwez
PMID: 27367029
Journal: Antioxid Redox Signal. 2017 Jun 10;26(17):1000-1008.
Title: NO(*) and Pancreatic Cancer: A Complex Interaction with Therapeutic Potential.
Author: Wang, Jian|Hussain, S Perwez
PMID: 27510096
Journal: Hum Vaccin Immunother. 2017 May 4;13(5):1105-1108.
Title: Targeting iNOS to increase efficacy of immunotherapies.
Author: Ekmekcioglu, Suhendan|Grimm, Elizabeth A|Roszik, Jason
PMID: 28121247
Journal: Cancer Cytopathol. 2018 May;126(5):326-335.
Title: Well differentiated grade 3 pancreatic neuroendocrine tumors compared with related neoplasms: A morphologic study.
Author: Sigel, Carlie S|Krauss Silva, Vitor Werneck|Reid, Michelle D|Chhieng, David|Basturk, Olca|Sigel, Keith M|Daniel, Tanisha D|Klimstra, David S|Tang, Laura H
PMID: 29451738
Journal: Mol Carcinog. 2018 Jul 23.
Title: Low dose radiation primed iNOS + M1macrophages modulate angiogenic programming of tumor derived endothelium.
Author: Nadella, Vinod|Singh, Sandhya|Jain, Aklank|Jain, Manju|Vasquez, Karen M|Sharma, Ashok|Tanwar, Pranay|Rath, Goura Kishore|Prakash, Hridayesh
PMID: 30035346