Primary Site >> Colorectal Cancer

Gene >> NOD2

Journal: Arch Surg. 2000 May;135(5):582-5.
Title: Use of a microsatellite marker in predicting dysplasia in ulcerative colitis.
Author: Hunt, L E|Eichenberger, M R|Petras, R|Galandiuk, S
PMID: 10807284
Journal: Cancer Res. 2004 Mar 1;64(5):1604-6.
Title: The NOD2 3020insC mutation and the risk of colorectal cancer.
Author: Kurzawski, Grzegorz|Suchy, Janina|Kladny, Jozef|Grabowska, Ewa|Mierzejewski, Marek|Jakubowska, Anna|Debniak, Tadeusz|Cybulski, Cezary|Kowalska, Elsbieta|Szych, Zbigniew|Domagala, Wenancjusz|Scott, Rodney J|Lubinski, Jan
PMID: 14996717
Journal: Fam Cancer. 2004;3(3-4):229-32.
Title: Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer.
Author: Lynch, Henry T|Brand, Randall E|Locker, Gershon Y
PMID: 15516846
Journal: Cancer Res. 2004 Oct 15;64(20):7245-7.
Title: NOD2 3020insC alone is not sufficient for colorectal cancer predisposition.
Author: Alhopuro, Pia|Ahvenainen, Taru|Mecklin, Jukka-Pekka|Juhola, Matti|Jarvinen, Heikki J|Karhu, Auli|Aaltonen, Lauri A
PMID: 15492242
Journal: Clin Gastroenterol Hepatol. 2004 Jan;2(1):9-13.
Title: Gastrointestinal basic science 2002-2003: the year in review.
Author: Brenner, David A
PMID: 15017626
Journal: Cancer Res. 2004 Aug 1;64(15):5525; author reply 5525-6.
Title: NOD2 and colorectal cancer: guilt by non-association.
Author: Gasche, Christoph|Carethers, John M
PMID: 15289364
Journal: Int J Cancer. 2005 Apr 10;114(3):433-5.
Title: Association between mutations in the CARD15/NOD2 gene and colorectal cancer in a Greek population.
Author: Papaconstantinou, Ioannis|Theodoropoulos, George|Gazouli, Maria|Panoussopoulos, Dimitris|Mantzaris, Gerassimos J|Felekouras, Evangelos|Bramis, John
PMID: 15578724
Journal: Breast Cancer Res Treat. 2005 Jan;89(1):91-3.
Title: The 3020insC allele of NOD2 predisposes to early-onset breast cancer.
Author: Huzarski, Tomasz|Lener, Marcin|Domagala, Wenancjusz|Gronwald, Jacek|Byrski, Tomasz|Kurzawski, Grzegorz|Suchy, Janina|Chosia, Maria|Woyton, Janusz|Ucinski, Michal|Narod, Steven A|Lubinski, Jan
PMID: 15666202
Journal: Eur J Cancer Prev. 2005 Apr;14(2):143-6.
Title: NOD2 variants and the risk of malignant melanoma.
Author: Debniak, T|Kurzawski, G|Huzarski, T|Byrski, T|Gronwald, J|Debniak, B|Rozmiarek, A|Dziuba, I|Zlowocka, E|Suchy, J|Gorski, B|Cybulski, C|Mierzejewski, M|Masojc, B|Medrek, K|Oszurek, O|Lubinski, J
PMID: 15785318
Journal: Hered Cancer Clin Pract. 2005 Mar 15;3(2):59-63.
Title: The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs.
Author: Lubinski, Jan|Huzarski, Tomasz|Kurzawski, Grzegorz|Suchy, Janina|Masojc, Bartlomiej|Mierzejewski, Marek|Lener, Marcin|Domagala, Wenancjusz|Chosia, Maria|Teodorczyk, Urszula|Medrek, Krzysztof|Debniak, Tadeusz|Zlowocka, Elzbieta|Gronwald, Jacek|Byrski, Toma
PMID: 20223031
Journal: Cancer Res. 2006 Mar 1;66(5):2532-5.
Title: Caspase recruitment domain-containing protein 15 mutations in patients with colorectal cancer.
Author: Roberts, Rebecca L|Gearry, Richard B|Allington, Melanie D E|Morrin, Helen R|Robinson, Bridget A|Frizelle, Frank A
PMID: 16510569
Journal: Hered Cancer Clin Pract. 2006 Jan 15;4(1):48-51.
Title: Pilot study on low penetrance breast and colorectal cancer predisposition markers in latvia.
Author: Irmejs, Arvids|Miklasevics, Edvins|Boroschenko, Viktors|Gardovskis, Andris|Vanags, Andrejs|Melbarde-Gorkusa, Inga|Bitina, Marianna|Suchy, Janina|Gardovskis, Janis
PMID: 20223004
Journal: BMC Cancer. 2007 Mar 27;7:54.
Title: Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients.
Author: Lakatos, Peter Laszlo|Hitre, Erika|Szalay, Ferenc|Zinober, Kerstin|Fuszek, Peter|Lakatos, Laszlo|Fischer, Simon|Osztovits, Janos|Gemela, Orsolya|Veres, Gabor|Papp, Janos|Ferenci, Peter
PMID: 17389035
Journal: Int J Cancer. 2007 Jul 1;121(1):76-9.
Title: No evidence for association of NOD2 R702W and G908R with colorectal cancer.
Author: Tuupanen, Sari|Alhopuro, Pia|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Aaltonen, Lauri A
PMID: 17351900
Journal: BMC Cancer. 2008 Apr 23;8:112.
Title: Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk.
Author: Suchy, Janina|Klujszo-Grabowska, Ewa|Kladny, Jozef|Cybulski, Cezary|Wokolorczyk, Dominika|Szymanska-Pasternak, Jolanta|Kurzawski, Grzegorz|Scott, Rodney J|Lubinski, Jan
PMID: 18433468
Journal: Med Sci Monit. 2008 Sep;14(9):CR480-4.
Title: NOD2/CARD15 polymorphism in patients with rectal cancer.
Author: Szeliga, Jacek|Sondka, Zbyslaw|Jackowski, Marek|Jarkiewicz-Tretyn, Joanna|Tretyn, Andrzej|Malenczyk, Marek
PMID: 18758419
Journal: World J Gastroenterol. 2008 Oct 14;14(38):5834-41.
Title: Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival.
Author: Cruickshank, Sheena-M|Wakenshaw, Louise|Cardone, John|Howdle, Peter-D|Murray, Peter-J|Carding, Simon-R
PMID: 18855982
Journal: Indian J Gastroenterol. 2008 Sep-Oct;27(5):201-3.
Title: Common NOD2 mutations are absent in patients with Crohn's disease in India.
Author: Pugazhendhi, Srinivasan|Amte, Aneesh|Balamurugan, Ramadass|Subramanian, Venkataraman|Ramakrishna, Balakrishnan S
PMID: 19112191
Journal: Cancer Epidemiol. 2009 Aug;33(2):161-3.
Title: Clinical characteristics of tumors derived from colorectal cancer patients who harbor the tumor necrosis factor alpha-1031T/T and NOD2 3020insC polymorphism.
Author: Kladny, Jozef|Suchy, Janina|Klujszo-Grabowska, Ewa|Kacperski, Tomasz|Scott, Rodney J|Kurzawski, Grzegorz|Lubinski, Jan
PMID: 19679065
Journal: BMC Gastroenterol. 2009 Oct 20;9:79.
Title: Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer.
Author: Mockelmann, Nikolaus|von Schonfels, Witigo|Buch, Stephan|von Kampen, Oliver|Sipos, Bence|Egberts, Jan Hendrik|Rosenstiel, Philip|Franke, Andre|Brosch, Mario|Hinz, Sebastian|Roder, Christian|Kalthoff, Holger|Folsch, Ulrich R|Krawczak, Michael|Schreiber, St
PMID: 19843337
Journal: Dig Dis. 2010;28(4-5):590-5.
Title: Chronic inflammation, colorectal cancer and gene polymorphisms.
Author: Boland, C Richard
PMID: 21088407
Journal: Int J Colorectal Dis. 2010 Feb;25(2):161-8.
Title: Differential effects of NOD2 polymorphisms on colorectal cancer risk: a meta-analysis.
Author: Tian, Yun|Li, Yi|Hu, Zhenhua|Wang, Daqing|Sun, Xiyang|Ren, Changshan
PMID: 19787357
Journal: J Intern Med. 2010 Feb;267(2):228-36.
Title: NOD2/CARD15 genotype and common gastrointestinal diseases in 43,600 individuals.
Author: Yazdanyar, S|Nordestgaard, B G
PMID: 19570052
Journal: Int J Colorectal Dis. 2010 Oct;25(10):1211-9.
Title: CARD15 mutations and colorectal cancer in a South European country.
Author: Freire, Paulo|Portela, Francisco|Donato, Maria M|Figueiredo, Pedro|Ferreira, Manuela|Amaro, Pedro|Sa, Anabela|Andrade, Paulo|Gouveia, Hermano|Sofia, Carlos
PMID: 20676658
Journal: Nat Genet. 2011 Jan;43(1):43-7.
Title: Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease.
Author: Momozawa, Yukihide|Mni, Myriam|Nakamura, Kayo|Coppieters, Wouter|Almer, Sven|Amininejad, Leila|Cleynen, Isabelle|Colombel, Jean-Frederic|de Rijk, Peter|Dewit, Olivier|Finkel, Yigael|Gassull, Miquel A|Goossens, Dirk|Laukens, Debby|Lemann, Marc|Libioulle, C
PMID: 21151126
Journal: Fam Cancer. 2011 Jun;10(2):323-30.
Title: German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
Author: Schneider, Ralph|Slater, Emily P|Sina, Mercede|Habbe, Nils|Fendrich, Volker|Matthai, Elvira|Langer, Peter|Bartsch, Detlef K
PMID: 21207249
Journal: Gastroenterol Hepatol (N Y). 2011 Oct;7(10):652-9.
Title: Predictors of aggressive inflammatory bowel disease.
Author: Yarur, Andres J|Strobel, Sebastian G|Deshpande, Amar R|Abreu, Maria T
PMID: 22298958
Journal: Vnitr Lek. 2013 Nov;59(11):977-80.
Title: [Possibilities of genetic diagnostics of intestine tumour and inflammatory diseases in Slovakia].
Author: Desatova, B|Batovsky, M|Mlkva, I
PMID: 24279441
Journal: Scand J Gastroenterol. 2013 Oct;48(10):1188-97.
Title: Card15 mutations and gastric cancer in a Portuguese population.
Author: Freire, Paulo|Figueiredo, Pedro|Cardoso, Ricardo|Donato, Maria M|Sa, Anabela|Portela, Francisco|Romaozinho, Jose M|Sofia, Carlos
PMID: 24047397
Journal: Gut Microbes. 2013 Jul-Aug;4(4):353-6.
Title: NOD2 prevents emergence of disease-predisposing microbiota.
Author: Secher, Thomas|Normand, Sylvain|Chamaillard, Mathias
PMID: 23778641
Journal: Acta Biochim Pol. 2013;60(2):195-8. Epub 2013 Jun 6.
Title: Development of a new, simple and cost-effective diagnostic tool for genetic screening of hereditary colorectal cancer--the DNA microarray assay.
Author: Stojcev, Zoran|Banasiewicz, Tomasz|Kaszuba, Michal|Sikorski, Adam|Szczepkowski, Marek|Bobkiewicz, Adam|Paszkowski, Jacek|Krokowicz, Lukasz|Biczysko, Maciej|Szmeja, Jacek|Jurkowska, Monika|Majewski, Przemyslaw|Mackiewicz, Andrzej|Lamperska, Katarzyna|Drews
PMID: 23741719
Journal: Cancer Discov. 2013 Mar;3(3):OF17.
Title: NOD2 protects against colorectal cancer via regulation of gut bacteria.
Author:
PMID: 23475887
Journal: J Clin Invest. 2013 Feb;123(2):700-11.
Title: NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.
Author: Couturier-Maillard, Aurelie|Secher, Thomas|Rehman, Ateequr|Normand, Sylvain|De Arcangelis, Adele|Haesler, Robert|Huot, Ludovic|Grandjean, Teddy|Bressenot, Aude|Delanoye-Crespin, Anne|Gaillot, Olivier|Schreiber, Stefan|Lemoine, Yves|Ryffel, Bernhard|Hot, D
PMID: 23281400
Journal: Genet Mol Res. 2014 Mar 19;13(3):7079-85.
Title: NOD2/CARD15 variants in Malaysian patients with sporadic colorectal cancer.
Author: Lau, T P|Roslani, A C|Lian, L H|Lee, P C|Hilmi, I|Goh, K L|Chua, K H
PMID: 24682985
Journal: Med Oncol. 2014 May;31(5):954.
Title: 3020insC NOD2/CARD15 polymorphism associated with treatment of colorectal cancer.
Author: Omrane, Ines|Mezlini, Amel|Baroudi, Olfa|Stambouli, Nejla|Bougatef, Karim|Ayari, Hager|Medimegh, Imen|Bouzaienne, Hassen|Uhrhammer, Nancy|Bignon, Yves-Jean|Benammar-Elgaaied, Amel|Marrakchi, Raja
PMID: 24719038
Journal: Med Oncol. 2014 Sep;31(9):173.
Title: A miRNA-binding site single nucleotide polymorphism in the 3'-UTR region of the NOD2 gene is associated with colorectal cancer.
Author: Ahangari, Fatemeh|Salehi, Rasoul|Salehi, Mansour|Khanahmad, Hosein
PMID: 25148897
Journal: Biochim Biophys Acta. 2015 Aug;1856(1):28-38.
Title: The immune microenvironment of the colorectal tumor: Involvement of immunity genes and microRNAs belonging to the TH17 pathway.
Author: Omrane, Ines|Benammar-Elgaaied, Amel
PMID: 25911397
Journal: Oncotarget. 2015 Oct 20;6(32):33456-69.
Title: Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components.
Author: Liu, Rongrong|Truax, Agnieszka D|Chen, Liang|Hu, Peizhen|Li, Zengshan|Chen, Jun|Song, Chaojun|Chen, Lihua|Ting, Jenny Pan-Yun
PMID: 26378020
Journal: World J Gastrointest Surg. 2016 Apr 27;8(4):284-93.
Title: NOD2 mutations and colorectal cancer - Where do we stand?
Author: Branquinho, Diogo|Freire, Paulo|Sofia, Carlos
PMID: 27152134
Journal: Microrna. 2016;5(2):152-156.
Title: Lack of Association between NOD2 rs3135500 and IL12B rs1368439 microRNA Binding Site SNPs and Colorectal Cancer Susceptibility in an Iranian Population.
Author: Chaleshi, Vahid|Tajali, Raziye|Savabkar, Sanaz|Zali, Neda|Mojarad, Ehsan N|Haghazali, Mehrdad|Pasha, Sara|Aghdaei, Hamid A|Zali, Mohammad R|Vahedi, Mohsen
PMID: 27426943
Journal: Nutr Cancer. 2017 Feb-Mar;69(2):276-288.
Title: Vitamin D Reduces Colitis- and Inflammation-Associated Colorectal Cancer in Mice Independent of NOD2.
Author: Elimrani, Ihsan|Koenekoop, Jamie|Dionne, Serge|Marcil, Valerie|Delvin, Edgar|Levy, Emile|Seidman, Ernest G
PMID: 28045548
Journal: Oncoimmunology. 2017 Jan 19;6(3):e1282589.
Title: Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.
Author: Dong, Wenqian|Zhang, Huafeng|Yin, Xiaonan|Liu, Yuying|Chen, Degao|Liang, Xiaoyu|Jin, Xun|Lv, Jiadi|Ma, Jingwei|Tang, Ke|Hu, Zhuowei|Qin, Xiaofeng|Huang, Bo
PMID: 28405506