Primary Site >> Pancreatic Cancer

Gene >> NGF

Journal: J Clin Oncol. 1999 Aug;17(8):2419-28.
Title: Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer.
Author: Zhu, Z|Friess, H|diMola, F F|Zimmermann, A|Graber, H U|Korc, M|Buchler, M W
PMID: 10561305
Journal: Genomics. 1999 Nov 1;61(3):319-25.
Title: PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1.
Author: Yang, X H|Huang, S
PMID: 10552934
Journal: J Histochem Cytochem. 2001 Oct;49(10):1205-10.
Title: Expression of nerve growth factors in pancreatic neural tissue and pancreatic cancer.
Author: Schneider, M B|Standop, J|Ulrich, A|Wittel, U|Friess, H|Andren-Sandberg, A|Pour, P M
PMID: 11561004
Journal: Mol Carcinog. 2002 Nov;35(3):138-47.
Title: Nerve growth factor and enhancement of proliferation, invasion, and tumorigenicity of pancreatic cancer cells.
Author: Zhu, Zhaowen|Kleeff, Jorg|Kayed, Hany|Wang, Li|Korc, Murray|Buchler, Markus W|Friess, Helmut
PMID: 12410565
Journal: Ann Pathol. 2002 Oct;22(5):349-55.
Title: [Molecular pathways of pancreatic carcinogenesis].
Author: Torrisani, Jerome|Buscail, Louis
PMID: 12483152
Journal: Clin Exp Metastasis. 2004;21(4):285-92.
Title: Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells.
Author: Okada, Yuji|Eibl, Guido|Guha, Sushovan|Duffy, John P|Reber, Howard A|Hines, Oscar J
PMID: 15554384
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2006 Aug;26(8):1251-3.
Title: [Relation of nerve growth factor expression with perineural invasion and pain in pancreatic cancer].
Author: Hua, Zhu-ming|Li, Zhen|Lou, Dong-lan
PMID: 16939930
Journal: Oncol Rep. 2007 Sep;18(3):673-7.
Title: siRNA directed against TrkA sensitizes human pancreatic cancer cells to apoptosis induced by gemcitabine through an inactivation of PI3K/Akt-dependent pathway.
Author: Liu, Dapeng|Zhang, Yong|Dang, Chengxue|Ma, Qingyong|Lee, Woo|Chen, Wuke
PMID: 17671718
Journal: J Gastroenterol Hepatol. 2008 Dec;23(12):1852-9.
Title: Expression of nerve growth factor and tyrosine kinase receptor A and correlation with perineural invasion in pancreatic cancer.
Author: Ma, Jun|Jiang, Yumei|Jiang, Yuhua|Sun, Yan|Zhao, Xueming
PMID: 19120874
Journal: Eur J Surg Oncol. 2009 Aug;35(8):826-32.
Title: Patterns of expression and function of the p75(NGFR) protein in pancreatic cancer cells and tumours.
Author: Wang, W|Zhao, H|Zhang, S|Kang, E|Chen, Y|Ni, C|Zhang, S|Zhu, M
PMID: 19041213
Journal: Growth Factors. 2009 Oct;27(5):289-99.
Title: Transforming growth factor-beta induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway.
Author: Haas, Stephan L|Fitzner, Brit|Jaster, Robert|Wiercinska, Eliza|Gaitantzi, Haristi|Jesnowski, Ralf|Lohr, J-Matthias|Singer, Manfred V|Dooley, Steven|Breitkopf, Katja
PMID: 19639490
Journal: Zhonghua Nei Ke Za Zhi. 2009 Jul;48(7):562-5.
Title: [The expression and significance of nerve growth factor and its receptors in pancreatic ductal adenocarcinoma].
Author: Meng, Ling-Xin|Ding, Zhao-Jun|Chen, Xi-Ping|Fei, Li-Sheng|Chi, Yu-Hua|Zhao, Zhi-Gang|Wang, Xiao-Fang|Hao, Xi-Shan
PMID: 19957796
Journal: Ann Surg. 2010 May;251(5):923-31.
Title: Nerve growth factor and artemin are paracrine mediators of pancreatic neuropathy in pancreatic adenocarcinoma.
Author: Ceyhan, Guralp O|Schafer, Karl-Herbert|Kerscher, Annika G|Rauch, Ulrich|Demir, Ihsan Ekin|Kadihasanoglu, Mustafa|Bohm, Carolin|Muller, Michael W|Buchler, Markus W|Giese, Nathalia A|Erkan, Mert|Friess, Helmut
PMID: 20395845
Journal: J Oral Maxillofac Surg. 2010 Jun;68(6):1290-5.
Title: Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion?
Author: Kolokythas, Antonia|Cox, Darren P|Dekker, Nusi|Schmidt, Brian L
PMID: 20363547
Journal: PLoS One. 2011 Feb 28;6(2):e17385.
Title: Relationship between neural alteration and perineural invasion in pancreatic cancer patients with hyperglycemia.
Author: Li, Junhui|Ma, Qingyong|Liu, Han|Guo, Kun|Li, Feng|Li, Wei|Han, Liang|Wang, Fengfei|Wu, Erxi
PMID: 21386984
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2012 Mar;32(3):296-300.
Title: [Responses of pancreatic cancer cells to stimulations by nerve growth factor and the role of Trk-A expression].
Author: Diao, Dong-Mei|Song, Yong-Chun|Hou, Ni|Xu, Hai-Fei|Wang, Jian-Guang|Dang, Cheng-Xue
PMID: 22445970
Journal: Clin Cancer Res. 2013 Jan 1;19(1):50-61.
Title: The severity of neural invasion is associated with shortened survival in colon cancer.
Author: Liebl, Florian|Demir, Ihsan Ekin|Rosenberg, Robert|Boldis, Alexandra|Yildiz, Esra|Kujundzic, Kristina|Kehl, Timo|Dischl, Dominic|Schuster, Tibor|Maak, Matthias|Becker, Karen|Langer, Rupert|Laschinger, Melanie|Friess, Helmut|Ceyhan, Guralp O
PMID: 23147996
Journal: Mol Cancer Ther. 2013 Mar;12(3):264-73.
Title: Interaction of the sympathetic nerve with pancreatic cancer cells promotes perineural invasion through the activation of STAT3 signaling.
Author: Guo, Kun|Ma, Qingyong|Li, Junhui|Wang, Zheng|Shan, Tao|Li, Wei|Xu, Qinhong|Xie, Keping
PMID: 23288783
Journal: Mol Carcinog. 2014 Oct;53(10):787-92.
Title: Up-regulated cten by FGF2 contributes to FGF2-mediated cell migration.
Author: Hung, Shih-Ya|Shih, Yi-Ping|Chen, Michelle|Lo, Su Hao
PMID: 23625726
Journal: J Natl Cancer Inst. 2014 Aug 8;106(8). pii: dju184.
Title: Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion.
Author: Demir, Ihsan Ekin|Boldis, Alexandra|Pfitzinger, Paulo L|Teller, Steffen|Brunner, Eva|Klose, Natascha|Kehl, Timo|Maak, Matthias|Lesina, Marina|Laschinger, Melanie|Janssen, Klaus-Peter|Algul, Hana|Friess, Helmut|Ceyhan, Guralp O
PMID: 25106646
Journal: Eur Rev Med Pharmacol Sci. 2015 Sep;19(18):3385-90.
Title: Serum nerve growth factor level indicates therapeutic efficacy of 125I seed implantation in advanced pancreatic adenocarcinoma.
Author: Xu, J-B|Yang, X-C|Guo, J-H|Chen, J-Y|Shang, Y|Liu, W-J|Wang, T-M|Zou, L
PMID: 26439032
Journal: Oncotarget. 2016 Apr 5;7(14):18146-58.
Title: Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway.
Author: Han, Liang|Ma, Jiguang|Duan, Wanxing|Zhang, Lun|Yu, Shuo|Xu, Qinhong|Lei, Jianjun|Li, Xuqi|Wang, Zheng|Wu, Zheng|Huang, Jason H|Wu, Erxi|Ma, Qingyong|Ma, Zhenhua
PMID: 26934446
Journal: Pancreatology. 2016 Nov - Dec;16(6):1005-1014.
Title: Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer.
Author: Xin, Beibei|He, Xiaodan|Wang, Juan|Cai, Jun|Wei, Wei|Zhang, Ti|Shen, Xiaohong
PMID: 27654574
Journal: Nat Commun. 2017 Apr 25;8:15130.
Title: Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer.
Author: Lei, Yifeng|Tang, Lixue|Xie, Yangzhouyun|Xianyu, Yunlei|Zhang, Lingmin|Wang, Peng|Hamada, Yoh|Jiang, Kai|Zheng, Wenfu|Jiang, Xingyu
PMID: 28440296
Journal: Cancer Cell. 2018 Jan 8;33(1):75-90.e7.
Title: beta2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Author: Renz, Bernhard W|Takahashi, Ryota|Tanaka, Takayuki|Macchini, Marina|Hayakawa, Yoku|Dantes, Zahra|Maurer, H Carlo|Chen, Xiaowei|Jiang, Zhengyu|Westphalen, C Benedikt|Ilmer, Matthias|Valenti, Giovanni|Mohanta, Sarajo K|Habenicht, Andreas J R|Middelhoff, Mor
PMID: 29249692
Journal: Pancreatology. 2018 May 12. pii: S1424-3903(18)30109-1.
Title: Stromal heterogeneity in pancreatic cancer and chronic pancreatitis.
Author: Haeberle, Lena|Steiger, Katja|Schlitter, Anna Melissa|Safi, Sami Alexander|Knoefel, Wolfram Trudo|Erkan, Mert|Esposito, Irene
PMID: 29778400