Primary Site >> Liver Cancer
Gene >> NFE2L2
| 1. | |||||||||||
| Journal: | Biochem J. 2004 Jun 1;380(Pt 2):515-21. | ||||||||||
| Title: | Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis. | ||||||||||
| Author: | Ikeda, Hiromi|Nishi, Shinzo|Sakai, Masaharu | ||||||||||
| PMID: | 14960151 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2006 Mar 10;281(10):6734-41. | ||||||||||
| Title: | CCAAT enhancer-binding protein alpha suppresses the rat placental glutathione S-transferase gene in normal liver. | ||||||||||
| Author: | Ikeda, Hiromi|Omoteyama, Kazuki|Yoshida, Kazuhiko|Nishi, Shinzo|Sakai, Masaharu | ||||||||||
| PMID: | 16407263 | ||||||||||
| 3. | |||||||||||
| Journal: | Biochem Pharmacol. 2006 Aug 14;72(4):455-62. | ||||||||||
| Title: | Bucillamine induces glutathione biosynthesis via activation of the transcription factor Nrf2. | ||||||||||
| Author: | Wielandt, Ana M|Vollrath, Valeska|Farias, Marcelo|Chianale, Jose | ||||||||||
| PMID: | 16806086 | ||||||||||
| 4. | |||||||||||
| Journal: | Pharm Res. 2008 Apr;25(4):836-44. | ||||||||||
| Title: | Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression. | ||||||||||
| Author: | Prawan, Auemduan|Keum, Young-Sam|Khor, Tin Oo|Yu, Siwang|Nair, Sujit|Li, Wenge|Hu, Longqin|Kong, Ah-Ng Tony | ||||||||||
| PMID: | 17657593 | ||||||||||
| 5. | |||||||||||
| Journal: | Toxicol Sci. 2008 May;103(1):46-56. | ||||||||||
| Title: | Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR. | ||||||||||
| Author: | Rosen, Mitchell B|Lee, Janice S|Ren, Hongzu|Vallanat, Beena|Liu, Jie|Waalkes, Michael P|Abbott, Barbara D|Lau, Christopher|Corton, J Christopher | ||||||||||
| PMID: | 18281256 | ||||||||||
| 6. | |||||||||||
| Journal: | Hepatology. 2008 Aug;48(2):487-96. | ||||||||||
| Title: | Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development. | ||||||||||
| Author: | Marhenke, Silke|Lamle, Jutta|Buitrago-Molina, Laura Elisa|Canon, Jose Manuel Fernandez|Geffers, Robert|Finegold, Milton|Sporn, Michael|Yamamoto, Masayuki|Manns, Michael P|Grompe, Markus|Vogel, Arndt | ||||||||||
| PMID: | 18666252 | ||||||||||
| 7. | |||||||||||
| Journal: | Med Hypotheses. 2008 Nov;71(5):730-6. | ||||||||||
| Title: | The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver. | ||||||||||
| Author: | Tao, Kai-Shan|Wang, Wen|Wang, Ling|Cao, Da-Yong|Li, Yong-Qi|Wu, Sheng-Xi|Dou, Ke-Feng | ||||||||||
| PMID: | 18701223 | ||||||||||
| 8. | |||||||||||
| Journal: | Planta Med. 2009 Oct;75(12):1314-8. | ||||||||||
| Title: | Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. | ||||||||||
| Author: | Lee, Saet Byoul|Kim, Chul Young|Lee, Hee Ju|Yun, Ji Ho|Nho, Chu Won | ||||||||||
| PMID: | 19452436 | ||||||||||
| 9. | |||||||||||
| Journal: | Nat Cell Biol. 2010 Mar;12(3):213-23. | ||||||||||
| Title: | The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. | ||||||||||
| Author: | Komatsu, Masaaki|Kurokawa, Hirofumi|Waguri, Satoshi|Taguchi, Keiko|Kobayashi, Akira|Ichimura, Yoshinobu|Sou, Yu-Shin|Ueno, Izumi|Sakamoto, Ayako|Tong, Kit I|Kim, Mihee|Nishito, Yasumasa|Iemura, Shun-ichiro|Natsume, Tohru|Ueno, Takashi|Kominami, Eiki|Motoh | ||||||||||
| PMID: | 20173742 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2010 Jun;3(6):753-63. | ||||||||||
| Title: | Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis. | ||||||||||
| Author: | Bishayee, Anupam|Barnes, Kendra F|Bhatia, Deepak|Darvesh, Altaf S|Carroll, Richard T | ||||||||||
| PMID: | 20501860 | ||||||||||
| 11. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2010 Sep 1;247(2):129-37. | ||||||||||
| Title: | Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response. | ||||||||||
| Author: | Gan, Nanqin|Mi, Lixin|Sun, Xiaoyun|Dai, Guofei|Chung, Fung-Lung|Song, Lirong | ||||||||||
| PMID: | 20600217 | ||||||||||
| 12. | |||||||||||
| Journal: | Chem Res Toxicol. 2010 Sep 20;23(9):1477-84. | ||||||||||
| Title: | Activation of Nrf2 by microcystin-LR provides advantages for liver cancer cell growth. | ||||||||||
| Author: | Gan, Nanqin|Sun, Xiaoyun|Song, Lirong | ||||||||||
| PMID: | 20722399 | ||||||||||
| 13. | |||||||||||
| Journal: | AAPS J. 2011 Mar;13(1):1-13. | ||||||||||
| Title: | Anti-inflammatory/Anti-oxidative stress activities and differential regulation of Nrf2-mediated genes by non-polar fractions of tea Chrysanthemum zawadskii and licorice Glycyrrhiza uralensis. | ||||||||||
| Author: | Wu, Tien-Yuan|Khor, Tin Oo|Saw, Constance Lay Lay|Loh, Stephanie C|Chen, Alvin I|Lim, Soon Sung|Park, Jung Han Yoon|Cai, Li|Kong, Ah-Ng Tony | ||||||||||
| PMID: | 20967519 | ||||||||||
| 14. | |||||||||||
| Journal: | Carcinogenesis. 2011 Jun;32(6):888-96. | ||||||||||
| Title: | Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. | ||||||||||
| Author: | Bishayee, Anupam|Bhatia, Deepak|Thoppil, Roslin J|Darvesh, Altaf S|Nevo, Eviatar|Lansky, Ephraim P | ||||||||||
| PMID: | 21389260 | ||||||||||
| 15. | |||||||||||
| Journal: | Toxicology. 2011 May 10;283(2-3):109-17. | ||||||||||
| Title: | Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine. | ||||||||||
| Author: | Shimamoto, Keisuke|Dewa, Yasuaki|Ishii, Yuji|Kemmochi, Sayaka|Taniai, Eriko|Hayashi, Hitomi|Imaoka, Masako|Morita, Reiko|Kuwata, Kazunori|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 21396975 | ||||||||||
| 16. | |||||||||||
| Journal: | J Cell Biol. 2011 Apr 18;193(2):275-84. | ||||||||||
| Title: | Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. | ||||||||||
| Author: | Inami, Yoshihiro|Waguri, Satoshi|Sakamoto, Ayako|Kouno, Tsuguka|Nakada, Kazuto|Hino, Okio|Watanabe, Sumio|Ando, Jin|Iwadate, Manabu|Yamamoto, Masayuki|Lee, Myung-Shik|Tanaka, Keiji|Komatsu, Masaaki | ||||||||||
| PMID: | 21482715 | ||||||||||
| 17. | |||||||||||
| Journal: | Autophagy. 2011 Sep;7(9):1088-90. Epub 2011 Sep 1. | ||||||||||
| Title: | Potential role of p62 in tumor development. | ||||||||||
| Author: | Komatsu, Masaaki | ||||||||||
| PMID: | 21617386 | ||||||||||
| 18. | |||||||||||
| Journal: | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011 Jun;27(6):608-10. | ||||||||||
| Title: | [Expression and distribution of Nrf2 in several hepatocellular carcinoma cell lines]. | ||||||||||
| Author: | Ma, Ren-Qiang|Zhang, Ming-xin|Wang, Jian-sheng|Cai, Hui|Yeer, Mai-ke|Duan, Xiao-yi | ||||||||||
| PMID: | 21651857 | ||||||||||
| 19. | |||||||||||
| Journal: | Free Radic Biol Med. 2011 Nov 1;51(9):1675-85. | ||||||||||
| Title: | Transcriptional modulation of the NAD(P)H:quinone oxidoreductase 1 by mercury in human hepatoma HepG2 cells. | ||||||||||
| Author: | Amara, Issa E A|El-Kadi, Ayman O S | ||||||||||
| PMID: | 21843634 | ||||||||||
| 20. | |||||||||||
| Journal: | Hepatology. 2012 Jun;55(6):1820-9. | ||||||||||
| Title: | Amplified in breast cancer 1 enhances human cholangiocarcinoma growth and chemoresistance by simultaneous activation of Akt and Nrf2 pathways. | ||||||||||
| Author: | Chen, Qiang|Li, Wenjiao|Wan, Yunyan|Xia, Xiaochun|Wu, Qiao|Chen, Yanling|Lai, Zhide|Yu, Chundong|Li, Wengang | ||||||||||
| PMID: | 22213475 | ||||||||||
| 21. | |||||||||||
| Journal: | J Biol Chem. 2012 Mar 23;287(13):9873-86. | ||||||||||
| Title: | Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis. | ||||||||||
| Author: | Niture, Suryakant K|Jaiswal, Anil K | ||||||||||
| PMID: | 22275372 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Sci. 2012 Apr;103(4):760-6. | ||||||||||
| Title: | Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma. | ||||||||||
| Author: | Inoue, Daisuke|Suzuki, Takashi|Mitsuishi, Yoichiro|Miki, Yasuhiro|Suzuki, Satoshi|Sugawara, Shunichi|Watanabe, Mika|Sakurada, Akira|Endo, Chiaki|Uruno, Akira|Sasano, Hironobu|Nakagawa, Takayuki|Satoh, Kennichi|Tanaka, Nobuyuki|Kubo, Hiroshi|Motohashi, Hoz | ||||||||||
| PMID: | 22320446 | ||||||||||
| 23. | |||||||||||
| Journal: | J Toxicol Sci. 2012;37(2):297-306. | ||||||||||
| Title: | Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action. | ||||||||||
| Author: | Hojo, Yuri|Shiraki, Ayako|Tsuchiya, Takuma|Shimamoto, Keisuke|Ishii, Yuji|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22467020 | ||||||||||
| 24. | |||||||||||
| Journal: | Anticancer Drugs. 2012 Jul;23(6):651-8. | ||||||||||
| Title: | The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors. | ||||||||||
| Author: | Hu, Rong|Chen, Nan|Yao, Jing|Zhao, Qing|Zhang, Fengyi|Li, Zhi-Yu|You, Qi-Dong|Guo, Qing-Long | ||||||||||
| PMID: | 22526619 | ||||||||||
| 25. | |||||||||||
| Journal: | Nat Genet. 2012 May 6;44(6):694-8. | ||||||||||
| Title: | Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. | ||||||||||
| Author: | Guichard, Cecile|Amaddeo, Giuliana|Imbeaud, Sandrine|Ladeiro, Yannick|Pelletier, Laura|Maad, Ichrafe Ben|Calderaro, Julien|Bioulac-Sage, Paulette|Letexier, Melanie|Degos, Francoise|Clement, Bruno|Balabaud, Charles|Chevet, Eric|Laurent, Alexis|Couchy, Gabr | ||||||||||
| PMID: | 22561517 | ||||||||||
| 26. | |||||||||||
| Journal: | Biochimie. 2012 Sep;94(9):1876-83. | ||||||||||
| Title: | Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells. | ||||||||||
| Author: | Smirnova, Olga A|Isaguliants, Maria G|Hyvonen, Mervi T|Keinanen, Tuomo A|Tunitskaya, Vera L|Vepsalainen, Jouko|Alhonen, Leena|Kochetkov, Sergey N|Ivanov, Alexander V | ||||||||||
| PMID: | 22579641 | ||||||||||
| 27. | |||||||||||
| Journal: | Toxicology. 2012 Sep 28;299(2-3):69-79. | ||||||||||
| Title: | Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1). | ||||||||||
| Author: | Gross-Steinmeyer, Kerstin|Eaton, David L | ||||||||||
| PMID: | 22640941 | ||||||||||
| 28. | |||||||||||
| Journal: | J Toxicol Sci. 2012;37(3):491-501. | ||||||||||
| Title: | Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action. | ||||||||||
| Author: | Hayashi, Hitomi|Shimamoto, Keisuke|Taniai, Eriko|Ishii, Yuji|Morita, Reiko|Suzuki, Kazuhiko|Shibutani, Makoto|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 22687989 | ||||||||||
| 29. | |||||||||||
| Journal: | PLoS One. 2012;7(7):e41676. | ||||||||||
| Title: | Induction of heme oxygenase-1 inhibits cell death in crotonaldehyde-stimulated HepG2 cells via the PKC-delta-p38-Nrf2 pathway. | ||||||||||
| Author: | Lee, Seung Eun|Yang, Hana|Jeong, Seong Il|Jin, Young-Ho|Park, Cheung-Seog|Park, Yong Seek | ||||||||||
| PMID: | 22848562 | ||||||||||
| 30. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2012 Nov 1;12(9):1173-90. | ||||||||||
| Title: | Chemoprevention of hepatocarcinogenesis with dietary isoprenic derivatives: cellular and molecular aspects. | ||||||||||
| Author: | Ong, Thomas Prates|Cardozo, Monica Testoni|de Conti, Aline|Moreno, Fernando Salvador | ||||||||||
| PMID: | 22873216 | ||||||||||
| 31. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2012 Nov 1;12(9):1244-57. | ||||||||||
| Title: | Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma. | ||||||||||
| Author: | Thoppil, Roslin J|Bhatia, Deepak|Barnes, Kendra F|Haznagy-Radnai, Erzsebet|Hohmann, Judit|Darvesh, Altaf S|Bishayee, Anupam | ||||||||||
| PMID: | 22873220 | ||||||||||
| 32. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2012 Aug;32(8):1093-7. | ||||||||||
| Title: | [Small interfering RNA-mediated Nrf2 gene knockdown enhances hirsutanols A-induced cytotoxicity in cancer cells]. | ||||||||||
| Author: | Ma, Jianguo|Li, Houjin|Deng, Rong|Feng, Gongkan|Zhu, Xiaofeng | ||||||||||
| PMID: | 22931598 | ||||||||||
| 33. | |||||||||||
| Journal: | J Ethnopharmacol. 2012 Nov 21;144(2):416-24. | ||||||||||
| Title: | Induction of quinone oxidoreductase 1 enzyme by Rhazya stricta through Nrf2-dependent mechanism. | ||||||||||
| Author: | El Gendy, Mohamed A M|Ali, Badreldin H|Michail, Karim|Siraki, Arno G|El-Kadi, Ayman O S | ||||||||||
| PMID: | 23026305 | ||||||||||
| 34. | |||||||||||
| Journal: | Biomed Pharmacother. 2012 Dec;66(8):612-6. | ||||||||||
| Title: | STAT3 & Cytochrome P450 2C9: a novel signaling pathway in liver cancer stem cells. | ||||||||||
| Author: | Myung, Sun Jung|Yoon, Jung-Hwan|Yu, Su Jong | ||||||||||
| PMID: | 23089473 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncoimmunology. 2012 Dec 1;1(9):1612-1613. | ||||||||||
| Title: | Next-generation sequencing identified new oncogenes and tumor suppressor genes in human hepatic tumors. | ||||||||||
| Author: | Amaddeo, Giuliana|Guichard, Cecile|Imbeaud, Sandrine|Zucman-Rossi, Jessica | ||||||||||
| PMID: | 23264911 | ||||||||||
| 36. | |||||||||||
| Journal: | J Nutr Biochem. 2013 Jan;24(1):178-87. | ||||||||||
| Title: | Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis. | ||||||||||
| Author: | Bishayee, Anupam|Thoppil, Roslin J|Darvesh, Altaf S|Ohanyan, Vahagn|Meszaros, J Gary|Bhatia, Deepak | ||||||||||
| PMID: | 22841394 | ||||||||||
| 37. | |||||||||||
| Journal: | Toxicol In Vitro. 2013 Feb;27(1):149-56. | ||||||||||
| Title: | Xanthohumol induces phase II enzymes via Nrf2 in human hepatocytes in vitro. | ||||||||||
| Author: | Krajka-Kuzniak, Violetta|Paluszczak, Jaroslaw|Baer-Dubowska, Wanda | ||||||||||
| PMID: | 23085367 | ||||||||||
| 38. | |||||||||||
| Journal: | Drug Metab Pharmacokinet. 2013;28(3):265-8. Epub 2012 Dec 11. | ||||||||||
| Title: | Cytotoxic effects of benzbromarone and its 1'-hydroxy metabolite in human hepatocarcinoma FLC4 cells cultured on micro-space cell culture plates. | ||||||||||
| Author: | Kobayashi, Kaoru|Kajiwara, Eri|Ishikawa, Masayuki|Mimura, Hanaka|Oka, Hidenobu|Ejiri, Yoko|Hosoda, Masaya|Chiba, Kan | ||||||||||
| PMID: | 23229783 | ||||||||||
| 39. | |||||||||||
| Journal: | Dig Dis Sci. 2013 Jun;58(6):1615-26. | ||||||||||
| Title: | The noncytotoxic dose of sorafenib sensitizes Bel-7402/5-FU cells to 5-FU by down-regulating 5-FU-induced Nrf2 expression. | ||||||||||
| Author: | Zhou, Suna|Ye, Wenguang|Duan, Xiaoyi|Zhang, Mingxin|Wang, Jiansheng | ||||||||||
| PMID: | 23314856 | ||||||||||
| 40. | |||||||||||
| Journal: | Toxicology. 2013 Apr 5;306:114-23. | ||||||||||
| Title: | Cadmium telluride quantum dots cause oxidative stress leading to extrinsic and intrinsic apoptosis in hepatocellular carcinoma HepG2 cells. | ||||||||||
| Author: | Nguyen, Kathy C|Willmore, William G|Tayabali, Azam F | ||||||||||
| PMID: | 23485651 | ||||||||||
| 41. | |||||||||||
| Journal: | Genome Res. 2013 May;23(5):800-11. | ||||||||||
| Title: | Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. | ||||||||||
| Author: | Kheradpour, Pouya|Ernst, Jason|Melnikov, Alexandre|Rogov, Peter|Wang, Li|Zhang, Xiaolan|Alston, Jessica|Mikkelsen, Tarjei S|Kellis, Manolis | ||||||||||
| PMID: | 23512712 | ||||||||||
| 42. | |||||||||||
| Journal: | Hepatology. 2013 Sep;58(3):1143-52. | ||||||||||
| Title: | The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice. | ||||||||||
| Author: | Buitrago-Molina, Laura Elisa|Marhenke, Silke|Longerich, Thomas|Sharma, Amar Deep|Boukouris, Aristeidis E|Geffers, Robert|Guigas, Bruno|Manns, Michael P|Vogel, Arndt | ||||||||||
| PMID: | 23526443 | ||||||||||
| 43. | |||||||||||
| Journal: | PLoS One. 2013 May 16;8(5):e63388. | ||||||||||
| Title: | Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis. | ||||||||||
| Author: | Endo, Hitoshi|Niioka, Maki|Kobayashi, Noriko|Tanaka, Mamoru|Watanabe, Tetsu | ||||||||||
| PMID: | 23696823 | ||||||||||
| 44. | |||||||||||
| Journal: | Hepatology. 2013 Nov;58(5):1693-702. | ||||||||||
| Title: | Identification of driver genes in hepatocellular carcinoma by exome sequencing. | ||||||||||
| Author: | Cleary, Sean P|Jeck, William R|Zhao, Xiaobei|Chen, Kui|Selitsky, Sara R|Savich, Gleb L|Tan, Ting-Xu|Wu, Michael C|Getz, Gad|Lawrence, Michael S|Parker, Joel S|Li, Jinyu|Powers, Scott|Kim, Hyeja|Fischer, Sandra|Guindi, Maha|Ghanekar, Anand|Chiang, Derek Y | ||||||||||
| PMID: | 23728943 | ||||||||||
| 45. | |||||||||||
| Journal: | Oxid Med Cell Longev. 2013;2013:763257. | ||||||||||
| Title: | Role of the Nrf2-ARE pathway in liver diseases. | ||||||||||
| Author: | Shin, Sang Mi|Yang, Ji Hye|Ki, Sung Hwan | ||||||||||
| PMID: | 23766860 | ||||||||||
| 46. | |||||||||||
| Journal: | Mutat Res. 2013 Aug 15;755(2):90-9. | ||||||||||
| Title: | Somatic changes in primary liver cancer in Russia: a pilot study. | ||||||||||
| Author: | Kalinina, Olga|Marchio, Agnes|Urbanskii, Aleksandr I|Tarkova, Aleksandra B|Rebbani, Khadija|Granov, Dmitri A|Dejean, Anne|Generalov, Mikhail I|Pineau, Pascal | ||||||||||
| PMID: | 23830926 | ||||||||||
| 47. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2013 Sep 27;439(3):333-9. | ||||||||||
| Title: | Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation. | ||||||||||
| Author: | Yun, Hong Shik|Hong, Eun-Hee|Lee, Su-Jae|Baek, Jeong-Hwa|Lee, Chang-Woo|Yim, Ji-Hye|Um, Hong-Duck|Hwang, Sang-Gu | ||||||||||
| PMID: | 24012673 | ||||||||||
| 48. | |||||||||||
| Journal: | J Cell Sci. 2013 Dec 15;126(Pt 24):5657-69. | ||||||||||
| Title: | Oncogene PKCepsilon controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2. | ||||||||||
| Author: | Niture, Suryakant K|Gnatt, Averell|Jaiswal, Anil K | ||||||||||
| PMID: | 24127568 | ||||||||||
| 49. | |||||||||||
| Journal: | Lipids Health Dis. 2013 Nov 4;12:165. | ||||||||||
| Title: | Nrf2 deletion causes "benign" simple steatosis to develop into nonalcoholic steatohepatitis in mice fed a high-fat diet. | ||||||||||
| Author: | Wang, Chunhua|Cui, Yizhe|Li, Chunyan|Zhang, Yanhua|Xu, Shang|Li, Xiaochong|Li, Hong|Zhang, Xiuying | ||||||||||
| PMID: | 24188280 | ||||||||||
| 50. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Dec 21;19(47):8873-9. | ||||||||||
| Title: | Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. | ||||||||||
| Author: | Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng | ||||||||||
| PMID: | 24379610 | ||||||||||
| 51. | |||||||||||
| Journal: | Biochim Biophys Acta. 2014 Jan;1840(1):219-44. | ||||||||||
| Title: | Berberine and S allyl cysteine mediated amelioration of DEN+CCl4 induced hepatocarcinoma. | ||||||||||
| Author: | Sengupta, Dipanwita|Chowdhury, Kaustav Dutta|Sarkar, Avik|Paul, Soumosish|Sadhukhan, Gobinda Chandra | ||||||||||
| PMID: | 23999088 | ||||||||||
| 52. | |||||||||||
| Journal: | J Gastroenterol. 2014 Sep;49(9):1324-32. | ||||||||||
| Title: | Frequent alteration of the protein synthesis of enzymes for glucose metabolism in hepatocellular carcinomas. | ||||||||||
| Author: | Shimizu, Takayuki|Inoue, Ken-ichi|Hachiya, Hiroyuki|Shibuya, Norisuke|Shimoda, Mitsugi|Kubota, Keiichi | ||||||||||
| PMID: | 24203292 | ||||||||||
| 53. | |||||||||||
| Journal: | Hepatology. 2014 Jun;59(6):2371-82. | ||||||||||
| Title: | NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice. | ||||||||||
| Author: | Shirasaki, Keiichi|Taguchi, Keiko|Unno, Michiaki|Motohashi, Hozumi|Yamamoto, Masayuki | ||||||||||
| PMID: | 24443206 | ||||||||||
| 54. | |||||||||||
| Journal: | Nat Rev Gastroenterol Hepatol. 2014 Jun;11(6):340-9. | ||||||||||
| Title: | Exploration of liver cancer genomes. | ||||||||||
| Author: | Shibata, Tatsuhiro|Aburatani, Hiroyuki | ||||||||||
| PMID: | 24473361 | ||||||||||
| 55. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2014 Jul;7(7):658-65. | ||||||||||
| Title: | Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold. | ||||||||||
| Author: | Johnson, Natalie M|Egner, Patricia A|Baxter, Victoria K|Sporn, Michael B|Wible, Ryan S|Sutter, Thomas R|Groopman, John D|Kensler, Thomas W|Roebuck, Bill D | ||||||||||
| PMID: | 24662598 | ||||||||||
| 56. | |||||||||||
| Journal: | PLoS One. 2014 Apr 1;9(4):e93599. | ||||||||||
| Title: | Maotai ameliorates diethylnitrosamine-initiated hepatocellular carcinoma formation in mice. | ||||||||||
| Author: | Yi, Xu|Long, Li|Yang, Chunzhang|Lu, Yingying|Cheng, Mingliang | ||||||||||
| PMID: | 24690765 | ||||||||||
| 57. | |||||||||||
| Journal: | Mol Pharm. 2014 Jun 2;11(6):1856-68. | ||||||||||
| Title: | The expression of genes involved in hepatocellular carcinoma chemoresistance is affected by mitochondrial genome depletion. | ||||||||||
| Author: | Gonzalez-Sanchez, Ester|Marin, Jose J G|Perez, Maria J | ||||||||||
| PMID: | 24824514 | ||||||||||
| 58. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2014 Jul 11;449(4):471-6. | ||||||||||
| Title: | Knockdown of hepatoma-derived growth factor-related protein-3 induces apoptosis of H1299 cells via ROS-dependent and p53-independent NF-kappaB activation. | ||||||||||
| Author: | Yun, Hong Shik|Baek, Jeong-Hwa|Yim, Ji-Hye|Lee, Su-Jae|Lee, Chang-Woo|Song, Jie-Young|Um, Hong-Duck|Park, Jong Kuk|Park, In-Chul|Hwang, Sang-Gu | ||||||||||
| PMID: | 24857986 | ||||||||||
| 59. | |||||||||||
| Journal: | Acta Neuropathol Commun. 2014 May 3;2:50. | ||||||||||
| Title: | Phosphorylation of serine 349 of p62 in Alzheimer's disease brain. | ||||||||||
| Author: | Tanji, Kunikazu|Miki, Yasuo|Ozaki, Taku|Maruyama, Atsushi|Yoshida, Hidemi|Mimura, Junsei|Matsumiya, Tomoh|Mori, Fumiaki|Imaizumi, Tadaatsu|Itoh, Ken|Kakita, Akiyoshi|Takahashi, Hitoshi|Wakabayashi, Koichi | ||||||||||
| PMID: | 24886973 | ||||||||||
| 60. | |||||||||||
| Journal: | Antioxid Redox Signal. 2014 Dec 20;21(18):2498-514. | ||||||||||
| Title: | The PTEN/NRF2 axis promotes human carcinogenesis. | ||||||||||
| Author: | Rojo, Ana I|Rada, Patricia|Mendiola, Marta|Ortega-Molina, Ana|Wojdyla, Katarzyna|Rogowska-Wrzesinska, Adelina|Hardisson, David|Serrano, Manuel|Cuadrado, Antonio | ||||||||||
| PMID: | 24892215 | ||||||||||
| 61. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2014 Jul;7(7):653-7. | ||||||||||
| Title: | Of mice, rats, and men: could Nrf2 activation protect against aflatoxin heptocarcinogenesis in humans? | ||||||||||
| Author: | Eaton, David L|Schaupp, Christopher M | ||||||||||
| PMID: | 24934619 | ||||||||||
| 62. | |||||||||||
| Journal: | J Hepatol. 2014 Nov;61(5):1178-83. | ||||||||||
| Title: | Paediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations. | ||||||||||
| Author: | Vilarinho, Silvia|Erson-Omay, E Zeynep|Harmanci, Akdes Serin|Morotti, Raffaella|Carrion-Grant, Geneive|Baranoski, Jacob|Knisely, A S|Ekong, Udeme|Emre, Sukru|Yasuno, Katsuhito|Bilguvar, Kaya|Gunel, Murat | ||||||||||
| PMID: | 25016225 | ||||||||||
| 63. | |||||||||||
| Journal: | Biochem Pharmacol. 2014 Sep 15;91(2):168-80. | ||||||||||
| Title: | AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells. | ||||||||||
| Author: | Sid, Brice|Glorieux, Christophe|Valenzuela, Manuel|Rommelaere, Guillaume|Najimi, Mustapha|Dejeans, Nicolas|Renard, Patricia|Verrax, Julien|Calderon, Pedro Buc | ||||||||||
| PMID: | 25058527 | ||||||||||
| 64. | |||||||||||
| Journal: | J Hepatol. 2014 Dec;61(6):1312-20. | ||||||||||
| Title: | The genomic landscape of hepatoblastoma and their progenies with HCC-like features. | ||||||||||
| Author: | Eichenmuller, Melanie|Trippel, Franziska|Kreuder, Michaela|Beck, Alexander|Schwarzmayr, Thomas|Haberle, Beate|Cairo, Stefano|Leuschner, Ivo|von Schweinitz, Dietrich|Strom, Tim M|Kappler, Roland | ||||||||||
| PMID: | 25135868 | ||||||||||
| 65. | |||||||||||
| Journal: | Eur J Pharmacol. 2014 Oct 15;741:247-53. | ||||||||||
| Title: | Sulforaphane inhibition of TPA-mediated PDCD4 downregulation contributes to suppression of c-Jun and induction of p21-dependent Nrf2 expression. | ||||||||||
| Author: | Cho, Jong-Ho|Kim, Young-Woo|Choi, Bu Young|Keum, Young-Sam | ||||||||||
| PMID: | 25169428 | ||||||||||
| 66. | |||||||||||
| Journal: | Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 Sep;45(5):739-43. | ||||||||||
| Title: | [The apoptotic mechanism of hepatocellular carcinoma cell line (HepG2) induced by arsenic trioxide]. | ||||||||||
| Author: | Zhao, Wei|Hu, Ya-Nan|Jiang, Xue-Jun|Chen, Cheng-Zhi|Zhang, Zun-Zhen | ||||||||||
| PMID: | 25341331 | ||||||||||
| 67. | |||||||||||
| Journal: | PLoS One. 2014 Dec 11;9(12):e114912. | ||||||||||
| Title: | A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma. | ||||||||||
| Author: | Marchio, Agnes|Bertani, Stephane|Rojas Rojas, Teresa|Doimi, Franco|Terris, Benoit|Deharo, Eric|Dejean, Anne|Ruiz, Eloy|Pineau, Pascal | ||||||||||
| PMID: | 25502816 | ||||||||||
| 68. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(23):10439-44. | ||||||||||
| Title: | miR-340 reverses cisplatin resistance of hepatocellular carcinoma cell lines by targeting Nrf2-dependent antioxidant pathway. | ||||||||||
| Author: | Shi, Liang|Chen, Zhan-Guo|Wu, Li-Li|Zheng, Jian-Jian|Yang, Jian-Rong|Chen, Xiao-Fei|Chen, Zeng-Qiang|Liu, Cun-Li|Chi, Sheng-Ying|Zheng, Jia-Ying|Huang, Hai-Xia|Lin, Xiang-Yang|Zheng, Fang | ||||||||||
| PMID: | 25556489 | ||||||||||
| 69. | |||||||||||
| Journal: | J Expo Sci Environ Epidemiol. 2015 May;25(3):256-63. | ||||||||||
| Title: | Mutation spectrum of hepatocellular carcinoma from eastern-European patients betrays the impact of a complex exposome. | ||||||||||
| Author: | Tanase, Anna-Maria|Marchio, Agnes|Dumitrascu, Traian|Dima, Simona|Herlea, Vlad|Oprisan, Gabriela|Dejean, Anne|Popescu, Irinel|Pineau, Pascal | ||||||||||
| PMID: | 24736102 | ||||||||||
| 70. | |||||||||||
| Journal: | Drug Des Devel Ther. 2014 Dec 17;9:127-46. | ||||||||||
| Title: | Schisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathway. | ||||||||||
| Author: | He, Jin-Lian|Zhou, Zhi-Wei|Yin, Juan-Juan|He, Chang-Qiang|Zhou, Shu-Feng|Yu, Yang | ||||||||||
| PMID: | 25552902 | ||||||||||
| 71. | |||||||||||
| Journal: | Toxicol Sci. 2015 Apr;144(2):393-405. | ||||||||||
| Title: | N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer. | ||||||||||
| Author: | Wang, Shuang|Sugamori, Kim S|Tung, Aveline|McPherson, J Peter|Grant, Denis M | ||||||||||
| PMID: | 25601990 | ||||||||||
| 72. | |||||||||||
| Journal: | Anticancer Drugs. 2015 Jun;26(5):555-64. | ||||||||||
| Title: | A Schiff base derivative for effective treatment of diethylnitrosamine-induced liver cancer in vivo. | ||||||||||
| Author: | Demirci, Selami|Dogan, Aysegul|Basak, Nese|Telci, Dilek|Dede, Bulent|Orhan, Cemal|Tuzcu, Mehmet|Sahin, Kazm|Sahin, Nurhan|Ozercan, Ibrahim Hanifi|Sahin, Fikrettin | ||||||||||
| PMID: | 25714251 | ||||||||||
| 73. | |||||||||||
| Journal: | Hepatology. 2015 Sep;62(3):851-62. | ||||||||||
| Title: | Nrf2, but not beta-catenin, mutation represents an early event in rat hepatocarcinogenesis. | ||||||||||
| Author: | Zavattari, Patrizia|Perra, Andrea|Menegon, Silvia|Kowalik, Marta Anna|Petrelli, Annalisa|Angioni, Maria Maddalena|Follenzi, Antonia|Quagliata, Luca|Ledda-Columbano, Giovanna Maria|Terracciano, Luigi|Giordano, Silvia|Columbano, Amedeo | ||||||||||
| PMID: | 25783764 | ||||||||||
| 74. | |||||||||||
| Journal: | J Physiol Biochem. 2015 Jun;71(2):227-38. | ||||||||||
| Title: | The activation of the Nrf2/ARE pathway in HepG2 hepatoma cells by phytochemicals and subsequent modulation of phase II and antioxidant enzyme expression. | ||||||||||
| Author: | Krajka-Kuzniak, Violetta|Paluszczak, Jaroslaw|Szaefer, Hanna|Baer-Dubowska, Wanda | ||||||||||
| PMID: | 25800511 | ||||||||||
| 75. | |||||||||||
| Journal: | Cell Physiol Biochem. 2015;35(6):2333-48. | ||||||||||
| Title: | MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil. | ||||||||||
| Author: | Shi, Liang|Wu, Lili|Chen, Zhanguo|Yang, Jianrong|Chen, Xiaofei|Yu, Fangyou|Zheng, Fang|Lin, Xiangyang | ||||||||||
| PMID: | 25896253 | ||||||||||
| 76. | |||||||||||
| Journal: | Cells. 2015 May 20;4(2):169-77. | ||||||||||
| Title: | What is Known Regarding the Participation of Factor Nrf-2 in Liver Regeneration? | ||||||||||
| Author: | Morales-Gonzalez, Jose A|Madrigal-Santillan, Eduardo|Morales-Gonzalez, Angel|Bautista, Mirandeli|Gayosso-Islas, Evila|Sanchez-Moreno, Cecilia | ||||||||||
| PMID: | 26010752 | ||||||||||
| 77. | |||||||||||
| Journal: | Am J Cancer Res. 2015 Mar 15;5(4):1368-81. eCollection 2015. | ||||||||||
| Title: | Disturbance of redox status enhances radiosensitivity of hepatocellular carcinoma. | ||||||||||
| Author: | Sun, Chao|Wang, Zhen-Hua|Liu, Xiong-Xiong|Yang, Li-Na|Wang, Yali|Liu, Yang|Mao, Ai-Hong|Liu, Yuan-Yuan|Zhou, Xin|Di, Cui-Xia|Gan, Lu|Zhang, Hong | ||||||||||
| PMID: | 26101703 | ||||||||||
| 78. | |||||||||||
| Journal: | Toxicol Sci. 2015 Oct;147(2):412-24. | ||||||||||
| Title: | Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication. | ||||||||||
| Author: | Sison-Young, Rowena L C|Mitsa, Dimitra|Jenkins, Rosalind E|Mottram, David|Alexandre, Eliane|Richert, Lysiane|Aerts, Helene|Weaver, Richard J|Jones, Robert P|Johann, Esther|Hewitt, Philip G|Ingelman-Sundberg, Magnus|Goldring, Christopher E P|Kitteringham, | ||||||||||
| PMID: | 26160117 | ||||||||||
| 79. | |||||||||||
| Journal: | BMC Cancer. 2015 Jul 21;15:531. | ||||||||||
| Title: | Nrf2 is a potential prognostic marker and promotes proliferation and invasion in human hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Mingxin|Zhang, Chao|Zhang, Lingmin|Yang, Qi|Zhou, Suna|Wen, Qinsheng|Wang, Jingjie | ||||||||||
| PMID: | 26194347 | ||||||||||
| 80. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Jul 1;8(7):8655-62. eCollection 2015. | ||||||||||
| Title: | N-acetylcysteine protects against liver injure induced by carbon tetrachloride via activation of the Nrf2/HO-1 pathway. | ||||||||||
| Author: | Cai, Zhaobin|Lou, Qi|Wang, Fugen|Li, Er|Sun, Jingjing|Fang, Hongying|Xi, Jianjun|Ju, Liping | ||||||||||
| PMID: | 26339453 | ||||||||||
| 81. | |||||||||||
| Journal: | Biochim Biophys Acta. 2015 Dec;1852(12):2603-17. | ||||||||||
| Title: | Molecular changes associated with chronic liver damage and neoplastic lesions in a murine model of hereditary tyrosinemia type 1. | ||||||||||
| Author: | Angileri, Francesca|Roy, Vincent|Morrow, Genevieve|Scoazec, Jean Yves|Gadot, Nicolas|Orejuela, Diana|Tanguay, Robert M | ||||||||||
| PMID: | 26360553 | ||||||||||
| 82. | |||||||||||
| Journal: | Free Radic Biol Med. 2015 Dec;89:1003-13. | ||||||||||
| Title: | Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells. | ||||||||||
| Author: | Ma, Wenbo|Li, Caiyue|Yin, Shikui|Liu, Jingxin|Gao, Chao|Lin, Zuoxian|Huang, Rongqi|Huang, Jufang|Li, Zhiyuan | ||||||||||
| PMID: | 26456053 | ||||||||||
| 83. | |||||||||||
| Journal: | Hepatobiliary Pancreat Dis Int. 2015 Oct;14(5):485-91. | ||||||||||
| Title: | |||||||||||