Primary Site >> Stomach Cancer

Gene >> NFE2L2

Journal: Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3410-5.
Title: Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
Author: Ramos-Gomez, M|Kwak, M K|Dolan, P M|Itoh, K|Yamamoto, M|Talalay, P|Kensler, T W
PMID: 11248092
Journal: Proc Natl Acad Sci U S A. 2002 May 28;99(11):7610-5.
Title: Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.
Author: Fahey, Jed W|Haristoy, Xavier|Dolan, Patrick M|Kensler, Thomas W|Scholtus, Isabelle|Stephenson, Katherine K|Talalay, Paul|Lozniewski, Alain
PMID: 12032331
Journal: Oncol Rep. 2008 Jan;19(1):211-6.
Title: The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium.
Author: Arisawa, Tomiyasu|Tahara, Tomomitsu|Shibata, Tomoyuki|Nagasaka, Mitsuo|Nakamura, Masakatsu|Kamiya, Yoshio|Fujita, Hiroshi|Yoshioka, Daisuke|Arima, Yuko|Okubo, Masaaki|Hirata, Ichiro|Nakano, Hiroshi
PMID: 18097597
Journal: Hepatogastroenterology. 2008 Mar-Apr;55(82-83):750-4.
Title: Nrf2 gene promoter polymorphism and gastric carcinogenesis.
Author: Arisawa, Tomiyasu|Tahara, Tomomitsu|Shibata, Tomoyuki|Nagasaka, Mitsuo|Nakamura, Masakatsu|Kamiya, Yoshio|Fujita, Hiroshi|Yoshioka, Daisuke|Okubo, Masaaki|Hirata, Ichiro|Nakano, Hiroshi
PMID: 18613447
Journal: Int J Mol Med. 2009 Mar;23(3):307-11.
Title: FGFR2-related pathogenesis and FGFR2-targeted therapeutics (Review).
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 19212647
Journal: Cancer Prev Res (Phila). 2009 Apr;2(4):353-60.
Title: Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans.
Author: Yanaka, Akinori|Fahey, Jed W|Fukumoto, Atsushi|Nakayama, Mari|Inoue, Souta|Zhang, Songhua|Tauchi, Masafumi|Suzuki, Hideo|Hyodo, Ichinosuke|Yamamoto, Masayuki
PMID: 19349290
Journal: Pathol Res Pract. 2011 Mar 15;207(3):169-73.
Title: Evaluation of Nrf2 and IGF-1 expression in benign, premalignant and malignant gastric lesions.
Author: Wang, Hong-Bo|Zhou, Cheng-Jun|Song, Su-zhen|Chen, Peng|Xu, Wei-hua|Liu, Bin|Zhu, Kong-xi|Yu, Wei-hua|Wu, Hong-lei|Wang, Hong-juan|Lin, Sen|Guo, Jian-qiang|Qin, Cheng-yong
PMID: 21367536
Journal: Arch Toxicol. 2011 Apr;85(4):273-84.
Title: Nrf2: control of sensitivity to carcinogens.
Author: Slocum, Stephen L|Kensler, Thomas W
PMID: 21369766
Journal: Curr Pharm Des. 2011;17(16):1532-40.
Title: Sulforaphane enhances protection and repair of gastric mucosa against oxidative stress in vitro, and demonstrates anti-inflammatory effects on Helicobacter pylori-infected gastric mucosae in mice and human subjects.
Author: Yanaka, Akinori
PMID: 21548875
Journal: Biochem Pharmacol. 2013 Oct 1;86(7):872-87.
Title: Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: the role of IL-6 signaling and Nrf2/AKR1C axis identification.
Author: Chen, Chih-Cheng|Chu, Chia-Bao|Liu, Ko-Jiunn|Huang, Chi-Ying F|Chang, Jang-Yang|Pan, Wen-Yu|Chen, Huang-Hui|Cheng, Yun-Hsia|Lee, Kuan-Der|Chen, Miao-Fen|Kuo, Ching-Chuan|Chen, Li-Tzong
PMID: 23933386
Journal: Asian Pac J Cancer Prev. 2013;14(9):5231-5.
Title: Nrf2 overexpression predicts prognosis and 5-FU resistance in gastric cancer.
Author: Hu, Xiu-Feng|Yao, Jun|Gao, She-Gan|Wang, Xin-Shuai|Peng, Xiu-Qing|Yang, Yan-Tong|Feng, Xiao-Shan
PMID: 24175806
Journal: Arch Iran Med. 2014 Apr;17(4):286-92.
Title: Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions.
Author: Abedi-Ardekani, Behnoush|Hainaut, Pierre
PMID: 24724606
Journal: Molecules. 2014 Jul 24;19(8):10818-31.
Title: Cudarflavone B provides neuroprotection against glutamate-induced mouse hippocampal HT22 cell damage through the Nrf2 and PI3K/Akt signaling pathways.
Author: Lee, Dong-Sung|Ko, Wonmin|Kim, Dong-Cheol|Kim, Youn-Chul|Jeong, Gil-Saeng
PMID: 25061726
Journal: Int J Clin Exp Med. 2015 Aug 15;8(8):13235-42. eCollection 2015.
Title: Correlation between expression of NF-E2-related factor 2 and progression of gastric cancer.
Author: Bao, Jie|Li, Jiansheng|Li, Dongying|Li, Zhenjie
PMID: 26550248
Journal: Int J Mol Sci. 2015 Nov 20;16(11):27757-69.
Title: Resveratrol Protects against Helicobacter pylori-Associated Gastritis by Combating Oxidative Stress.
Author: Zhang, Xiaolin|Jiang, Anmin|Qi, Banghua|Ma, Zhongyou|Xiong, Youyi|Dou, Jinfeng|Wang, Jianfei
PMID: 26610474
Journal: Med Sci Monit. 2015 Sep 27;21:2893-9.
Title: Correlation Between Nuclear Factor E2-Related Factor 2 Expression and Gastric Cancer Progression.
Author: Zheng, Hongyu|Nong, Zhiwei|Lu, Guohao
PMID: 26410168
Journal: BMC Cancer. 2015 Jan 15;15:5.
Title: Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer.
Author: Kawasaki, Yota|Ishigami, Sumiya|Arigami, Takaaki|Uenosono, Yoshikazu|Yanagita, Shigehiro|Uchikado, Yasuto|Kita, Yoshiaki|Nishizono, Yuka|Okumura, Hiroshi|Nakajo, Akihiro|Kijima, Yuko|Maemura, Kosei|Natsugoe, Shoji
PMID: 25588809
Journal: Cell Death Dis. 2016 Feb 18;7:e2106.
Title: Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo.
Author: Deng, C|Zhang, B|Zhang, S|Duan, C|Cao, Y|Kang, W|Yan, H|Ding, X|Zhou, F|Wu, L|Duan, G|Shen, S|Xu, G|Zhang, W|Chen, M|Huang, S|Zhang, X|Lv, Y|Ling, T|Wang, L|Zou, X
PMID: 26890145
Journal: Oncogene. 2016 Sep 22;35(38):5000-9.
Title: RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma.
Author: Sakurai, T|Isogaya, K|Sakai, S|Morikawa, M|Morishita, Y|Ehata, S|Miyazono, K|Koinuma, D
PMID: 26923328
Journal: Biomol Ther (Seoul). 2016 Sep 1;24(5):501-9.
Title: Shikonin Induces Apoptotic Cell Death via Regulation of p53 and Nrf2 in AGS Human Stomach Carcinoma Cells.
Author: Ko, Hyeonseok|Kim, Sun-Joong|Shim, So Hee|Chang, HyoIhl|Ha, Chang Hoon
PMID: 27257011
Journal: Tohoku J Exp Med. 2016 Aug;239(4):279-85.
Title: Sodium Selenite Inhibits Proliferation of Gastric Cancer Cells by Inducing SBP1 Expression.
Author: Gong, Jianzhuang|Li, Li
PMID: 27477809
Journal: Free Radic Biol Med. 2017 Mar;104:75-103.
Title: Redox signaling in the gastrointestinal tract.
Author: Perez, Salvador|Talens-Visconti, Raquel|Rius-Perez, Sergio|Finamor, Isabela|Sastre, Juan
PMID: 28062361
Journal: Acta Pharmacol Sin. 2017 Jul;38(7):1048-1058.
Title: Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment.
Author: Jiang, Xiao-Yan|Zhu, Xiao-Song|Xu, Hong-Ya|Zhao, Zhong-Xi|Li, Si-Ying|Li, Shan-Zhong|Cai, Jian-Hua|Cao, Ji-Min
PMID: 28344324
Journal: Microb Pathog. 2017 Jul;108:71-77.
Title: Evaluation of the antioxidant properties of carexanes in AGS cells transfected with the Helicobacter pylori's protein HspB.
Author: Buommino, Elisabetta|D'Abrosca, Brigida|Donnarumma, Giovanna|Parisi, Annamaria|Scognamiglio, Monica|Fiorentino, Antonio|De Luca, Antonio
PMID: 28479510
Journal: Sci Rep. 2017 Jun 5;7(1):2807.
Title: NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells.
Author: Yoon, Jung Hwan|Kim, Olga|Nam, Suk Woo|Lee, Jung Young|Park, Won Sang
PMID: 28584243
Journal: Sci Rep. 2017 Aug 29;7(1):9873.
Title: A novel chalcone derivative S17 induces apoptosis through ROS dependent DR5 up-regulation in gastric cancer cells.
Author: Zhang, Saiyang|Li, Tingyu|Zhang, Li|Wang, Xiangyu|Dong, Hangqi|Li, Lili|Fu, Dongjun|Li, Yongchun|Zi, Xiaolin|Liu, Hong-Min|Zhang, Yanbing|Xu, Hongde|Jin, Cheng-Yun
PMID: 28852176
Journal: Biomed Pharmacother. 2018 Jan;97:286-292.
Title: Nrf2 overexpression is associated with P-glycoprotein upregulation in gastric cancer.
Author: Jeddi, Farhad|Soozangar, Narges|Sadeghi, Mohammad Reza|Somi, Mohammad Hossein|Shirmohamadi, Masoud|Eftekhar-Sadat, Amir-Taher|Samadi, Nasser
PMID: 29091877
Journal: Biomol Ther (Seoul). 2018 Mar 1;26(2):175-181.
Title: Carbon Monoxide Ameliorates 6-Hydroxydopamine-Induced Cell Death in C6 Glioma Cells.
Author: Moon, Hyewon|Jang, Jung-Hee|Jang, Tae Chang|Park, Gyu Hwan
PMID: 29429149
Journal: Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F469-F478.
Title: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity.
Author: Sun, Liping|Liu, Jing|Yuan, Yanggang|Zhang, Xinzhou|Dong, Zheng
PMID: 29767555
Journal: Sheng Li Xue Bao. 2018 Aug 25;70(4):397-405.
Title: [Wogonoside reverses cisplatin resistance in SGC7901/cDDP cells through inhibition of PI3K/Akt/Nrf2/ARE signaling pathway].
Author: Wang, Li-Jun|Wang, Shi-Guang|Deng, Tong-Xing
PMID: 30112565
Journal: J Pathol. 2018 Oct 10.
Title: Keratin 17 in disease pathogenesis: from cancer to dermatoses.
Author: Yang, Luting|Zhang, Shaolong|Wang, Gang
PMID: 30306595