Primary Site >> Liver Cancer

Gene >> NEK2

Journal: Gut. 2009 May;58(5):679-87.
Title: Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.
Author: Calvisi, D F|Pinna, F|Ladu, S|Pellegrino, R|Simile, M M|Frau, M|De Miglio, M R|Tomasi, M L|Sanna, V|Muroni, M R|Feo, F|Pascale, R M
PMID: 19136513
Journal: PLoS One. 2012;7(4):e35510.
Title: Functional and topological properties in hepatocellular carcinoma transcriptome.
Author: Drozdov, Ignat|Bornschein, Jan|Wex, Thomas|Valeyev, Najl V|Tsoka, Sophia|Malfertheiner, Peter
PMID: 22539975
Journal: J Exp Clin Cancer Res. 2014 Jan 9;33:6.
Title: Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1.
Author: Huang, Lynn Y L|Lee, Ying-Shuan|Huang, Jiann-Jyh|Chang, Chia-chi|Chang, Jia-Ming|Chuang, Shih-Hsien|Kao, Kuo-Jang|Tsai, Yung-Jen|Tsai, Pei-Yi|Liu, Chia-Wei|Lin, Her-Sheng|Lau, Johnson Y N
PMID: 24401611
Journal: Cancer Chemother Pharmacol. 2014 Sep;74(3):511-20.
Title: Inhibition of Hec1 as a novel approach for treatment of primary liver cancer.
Author: Huang, Lynn Y L|Chang, Chia-chi|Lee, Ying-Shuan|Huang, Jiann-Jyh|Chuang, Shih-Hsien|Chang, Jia-Ming|Kao, Kuo-Jang|Lau, Gillian M G|Tsai, Pei-Yi|Liu, Chia-wei|Lin, Her-Sheng|Gish, Robert G|Lau, Johnson Y N
PMID: 25038613
Journal: J Gastroenterol Hepatol. 2016 Jan;31(1):256-64.
Title: Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Author: Wubetu, Gizachew Y|Shimada, Mitsuo|Morine, Yuji|Ikemoto, Tetsuya|Ishikawa, Daichi|Iwahashi, Shuichi|Yamada, Shinichiro|Saito, Yu|Arakawa, Yusuke|Imura, Satoru
PMID: 26241688
Journal: Tumour Biol. 2016 Feb;37(2):2023-35.
Title: Effect of silencing NEK2 on biological behaviors of HepG2 in human hepatoma cells and MAPK signal pathway.
Author: Zhang, Mei-Xia|Xu, Xi-Ming|Zhang, Peng|Han, Na-Na|Deng, Jun-Jian|Yu, Ting-Ting|Gan, Yuan-Yuan|He, Xiao-Qin|Long, Zhi-Xiong
PMID: 26337275
Journal: Anticancer Res. 2016 Feb;36(2):757-62.
Title: High NEK2 Expression Is a Predictor of Tumor Recurrence in Hepatocellular Carcinoma Patients After Hepatectomy.
Author: Wubetu, Gizachew Yismaw|Morine, Yuji|Teraoku, Hiroki|Yoshikawa, Masato|Ishikawa, Daichi|Yamada, Shinichiro|Ikemoto, Tetsuya|Saito, Y U|Imura, Satoru|Shimada, Mitsuo
PMID: 26851035
Journal: Oncol Rep. 2016 Aug;36(2):853-62.
Title: NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma.
Author: Lin, Shuang|Zhou, Senjun|Jiang, Shaojie|Liu, Xiaolong|Wang, Yifan|Zheng, Xueyong|Zhou, Haimeng|Li, Xuhui|Cai, Xiujun
PMID: 27349376
Journal: Oncol Rep. 2016 Oct;36(4):2193-9.
Title: Increased NEK2 in hepatocellular carcinoma promotes cancer progression and drug resistance by promoting PP1/Akt and Wnt activation.
Author: Wen, Sailan|Liu, Yuwu|Yang, Manyi|Yang, Keda|Huang, Jianghai|Feng, Deyun
PMID: 27509921
Journal: Int J Cancer. 2017 Apr 1;140(7):1581-1596.
Title: Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression.
Author: Wu, Sheng-Ming|Lin, Syuan-Ling|Lee, Kang-Yun|Chuang, Hsiao-Chi|Feng, Po-Hao|Cheng, Wan-Li|Liao, Chia-Jung|Chi, Hsiang-Cheng|Lin, Yang-Hsiang|Tsai, Chung-Ying|Chen, Wei-Jan|Yeh, Chau-Ting|Lin, Kwang-Huei
PMID: 27925179
Journal: Cancer Genet. 2017 Oct;216-217:37-51.
Title: Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets.
Author: Agarwal, Rahul|Narayan, Jitendra|Bhattacharyya, Amitava|Saraswat, Mayank|Tomar, Anil Kumar
PMID: 29025594
Journal: Oncotarget. 2017 May 5;8(32):52948-52959.
Title: MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma.
Author: Fu, Shun-Jun|Chen, Jian|Ji, Fei|Ju, Wei-Qiang|Zhao, Qiang|Chen, Mao-Gen|Guo, Zhi-Yong|Wu, Lin-Wei|Ma, Yi|Wang, Dong-Ping|Zhu, Xiao-Feng|He, Xiao-Shun
PMID: 28881785
Journal: Cancer Biomark. 2017 Jul 19;20(1):101-106.
Title: Low expression of NEK2 is associated with hepatocellular carcinoma progression and poor prognosis.
Author: Fu, Luoqin|Liu, Suxia|Wang, Huiju|Ma, Yingyu|Li, Li|He, Xianglei|Mou, Xiaozhou|Tong, Xiangmin|Hu, Zhiming|Ru, Guoqing
PMID: 28759960
Journal: Oncol Lett. 2017 Mar;13(3):1587-1594.
Title: NIMA-related kinase 2 regulates hepatocellular carcinoma cell growth and proliferation.
Author: Lai, Xiao-Bo|Nie, Yu-Qiang|Huang, Hong-Li|Li, Ying-Fei|Cao, Chuang-Yu|Yang, Hui|Shen, Bo|Feng, Zhi-Qiang
PMID: 28454295
Journal: Int J Oncol. 2017 Feb;50(2):405-413.
Title: NEK2 serves as a prognostic biomarker for hepatocellular carcinoma.
Author: Li, Gang|Zhong, Yanping|Shen, Qingrong|Zhou, Yi|Deng, Xiaofang|Li, Cuiping|Chen, Jiagui|Zhou, Ying|He, Min
PMID: 28101574
Journal: Diagn Pathol. 2017 Jan 13;12(1):4.
Title: A transcriptome profile in hepatocellular carcinomas based on integrated analysis of microarray studies.
Author: Wang, Feifei|Wang, Ruliang|Li, Qiuwen|Qu, Xueling|Hao, Yixin|Yang, Jingwen|Zhao, Huixia|Wang, Qian|Li, Guanghui|Zhang, Fengyun|Zhang, He|Zhou, Xuan|Peng, Xioumei|Bian, Yang|Xiao, Wenhua
PMID: 28086821
Journal: Oncol Rep. 2018 Mar;39(3):1023-1033.
Title: NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition.
Author: Zhang, Yi|Wang, Wei|Wang, Yifei|Huang, Xiaohui|Zhang, Zhaohui|Chen, Bin|Xie, Wenxuan|Li, Shaoqiang|Shen, Shunli|Peng, Baogang
PMID: 29399700
Journal: Ann Hepatol. 2018 Aug 24;17(5):843-856.
Title: NEK2 Promotes Hepatoma Metastasis and Serves as Biomarker for High Recurrence Risk after Hepatic Resection.
Author: Chang, Yu-Ying|Yen, Chia-Jui|Chan, Shih-Huang|Chou, Yi-Wen|Lee, Yun-Ping|Bao, Ching-Yu|Huang, Chien-Jung|Huang, Wenya
PMID: 30145571