Primary Site >> Colorectal Cancer

Gene >> NDRG4

Journal: J Natl Cancer Inst. 2009 Jul 1;101(13):916-27.
Title: N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.
Author: Melotte, Veerle|Lentjes, Marjolein H F M|van den Bosch, Sandra M|Hellebrekers, Debby M E I|de Hoon, Joep P J|Wouters, Kim A D|Daenen, Kathleen L J|Partouns-Hendriks, Iris E J M|Stessels, Filip|Louwagie, Joost|Smits, Kim M|Weijenberg, Matty P|Sanduleanu, S
PMID: 19535783
Journal: Cancer Res. 2010 Jan 15;70(2):609-20.
Title: Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.
Author: Wilson, Andrew J|Chueh, Anderly C|Togel, Lars|Corner, Georgia A|Ahmed, Naseem|Goel, Sanjay|Byun, Do-Sun|Nasser, Shannon|Houston, Michele A|Jhawer, Minaxi|Smartt, Helena J M|Murray, Lucas B|Nicholas, Courtney|Heerdt, Barbara G|Arango, Diego|Augenlicht, Leo
PMID: 20068171
Journal: Clin Gastroenterol Hepatol. 2012 Mar;10(3):272-7.e1.
Title: The stool DNA test is more accurate than the plasma septin 9 test in detecting colorectal neoplasia.
Author: Ahlquist, David A|Taylor, William R|Mahoney, Douglas W|Zou, Hongzhi|Domanico, Michael|Thibodeau, Stephen N|Boardman, Lisa A|Berger, Barry M|Lidgard, Graham P
PMID: 22019796
Journal: Clin Chem. 2012 Feb;58(2):375-83.
Title: Quantification of methylated markers with a multiplex methylation-specific technology.
Author: Zou, Hongzhi|Allawi, Hatim|Cao, Xiaoming|Domanico, Mike|Harrington, Jonathan|Taylor, William R|Yab, Tracy|Ahlquist, David A|Lidgard, Graham
PMID: 22194633
Journal: Aliment Pharmacol Ther. 2013 Mar;37(5):546-54.
Title: Stool DNA testing for the detection of colorectal neoplasia in patients with inflammatory bowel disease.
Author: Kisiel, J B|Yab, T C|Nazer Hussain, F T|Taylor, W R|Garrity-Park, M M|Sandborn, W J|Loftus, E V|Wolff, B G|Smyrk, T C|Itzkowitz, S H|Rubin, D T|Zou, H|Mahoney, D W|Ahlquist, D A
PMID: 23347191
Journal: Clin Gastroenterol Hepatol. 2013 Oct;11(10):1313-8.
Title: Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia.
Author: Lidgard, Graham P|Domanico, Michael J|Bruinsma, Janelle J|Light, James|Gagrat, Zubin D|Oldham-Haltom, Rebecca L|Fourrier, Keith D|Allawi, Hatim|Yab, Tracy C|Taylor, William R|Simonson, Julie A|Devens, Mary|Heigh, Russell I|Ahlquist, David A|Berger, Barry
PMID: 23639600
Journal: Inflamm Bowel Dis. 2014 Feb;20(2):271-7.
Title: FOXE1 and SYNE1 genes hypermethylation panel as promising biomarker in colitis-associated colorectal neoplasia.
Author: Papadia, Cinzia|Louwagie, Joost|Del Rio, Paolo|Grooteclaes, Madeleine|Coruzzi, Alessandro|Montana, Chiara|Novelli, Marco|Bordi, Cesare|de' Angelis, Gian Luigi|Bassett, Paul|Bigley, Joseph|Warren, Bryan|Atkin, Wendy|Forbes, Alastair
PMID: 24280874
Journal: PLoS One. 2014 Jan 20;9(1):e85659.
Title: Detection of colorectal serrated polyps by stool DNA testing: comparison with fecal immunochemical testing for occult blood (FIT).
Author: Heigh, Russell I|Yab, Tracy C|Taylor, William R|Hussain, Fareeda T N|Smyrk, Thomas C|Mahoney, Douglas W|Domanico, Michael J|Berger, Barry M|Lidgard, Graham P|Ahlquist, David A
PMID: 24465639
Journal: N Engl J Med. 2014 Apr 3;370(14):1287-97.
Title: Multitarget stool DNA testing for colorectal-cancer screening.
Author: Imperiale, Thomas F|Ransohoff, David F|Itzkowitz, Steven H|Levin, Theodore R|Lavin, Philip|Lidgard, Graham P|Ahlquist, David A|Berger, Barry M
PMID: 24645800
Journal: Dig Dis Sci. 2014 Aug;59(8):1764-7.
Title: Stool methylated DNA markers decrease following colorectal cancer resection--implications for surveillance.
Author: Kisiel, John B|Yab, Tracy C|Taylor, William R|Mahoney, Douglas W|Ahlquist, David A
PMID: 24993691
Journal: Oncol Lett. 2014 Oct;8(4):1751-1756.
Title: DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA.
Author: Lu, Hongna|Huang, Shiliang|Zhang, Xie|Wang, Danping|Zhang, Xuesong|Yuan, Xiaogang|Zhang, Qiubo|Huang, Zhigang
PMID: 25202404
Journal: Rinsho Byori. 2015 Mar;63(3):361-8.
Title: [Fecal Biomarker for Colorectal Cancer Diagnosis].
Author: Koga, Yoshikatsu|Yamazaki, Nobuyoshi|Matsumura, Yasuhiro
PMID: 26524859
Journal: World J Gastroenterol. 2015 Sep 21;21(35):10057-61.
Title: Stool DNA methylation assays in colorectal cancer screening.
Author: Kadiyska, Tanya|Nossikoff, Alexander
PMID: 26401070
Journal: Oncol Lett. 2015 Mar;9(3):1383-1387.
Title: Quantitative detection of methylated NDRG4 gene as a candidate biomarker for diagnosis of colorectal cancer.
Author: Xiao, Wenhua|Zhao, Huixia|Dong, Weiwei|Li, Quiwen|Zhu, Jianhua|Li, Guanghui|Zhang, Shufang|Ye, Ming
PMID: 25663916
Journal: Cancer Prev Res (Phila). 2015 Feb;8(2):157-64.
Title: Spectrin repeat containing nuclear envelope 1 and forkhead box protein E1 are promising markers for the detection of colorectal cancer in blood.
Author: Melotte, Veerle|Yi, Joo Mi|Lentjes, Marjolein H F M|Smits, Kim M|Van Neste, Leander|Niessen, Hanneke E C|Wouters, Kim A D|Louwagie, Joost|Schuebel, Kornel E|Herman, James G|Baylin, Stephen B|van Criekinge, Wim|Meijer, Gerrit A|Ahuja, Nita|van Engeland, Ma
PMID: 25538088
Journal: Oncotarget. 2015 Apr 10;6(10):7584-96.
Title: NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patients.
Author: Chu, Dake|Zhang, Zixi|Zhou, Yi|Li, Yunming|Zhu, Shaojun|Zhang, Jian|Zhao, Qingchuan|Ji, Gang|Wang, Weizhong|Zheng, Jianyong
PMID: 25749388
Journal: Oncotarget. 2016 Jan 12;7(2):1311-22.
Title: NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.
Author: Zheng, Jianyong|Li, Yunming|Zhu, Shaojun|Li, Jipeng|Zhao, Qingchuan|Ji, Gang|Wang, Weizhong|Chu, Dake
PMID: 26515606
Journal: J Gastrointest Cancer. 2016 Jun;47(2):143-51.
Title: Stool Investigations for Colorectal Cancer Screening: From Occult Blood Test to DNA Analysis.
Author: Iannone, Andrea|Losurdo, Giuseppe|Pricci, Maria|Girardi, Bruna|Massaro, Antonio|Principi, Mariabeatrice|Barone, Michele|Ierardi, Enzo|Di Leo, Alfredo
PMID: 26922358
Journal: Gut Liver. 2016 Sep 15;10(5):773-80.
Title: Field Cancerization in Sporadic Colon Cancer.
Author: Park, Soo-Kyung|Song, Chang Seok|Yang, Hyo-Joon|Jung, Yoon Suk|Choi, Kyu Yong|Koo, Dong Hoe|Kim, Kyung Eun|Jeong, Kyung Uk|Kim, Hyung Ook|Kim, Hungdai|Chun, Ho-Kyung|Park, Dong Il
PMID: 27114416
Journal: Biochim Biophys Acta. 2016 Aug;1866(1):106-20.
Title: DNA methylation based biomarkers in colorectal cancer: A systematic review.
Author: Lam, Kevin|Pan, Kathy|Linnekamp, Janneke Fiona|Medema, Jan Paul|Kandimalla, Raju
PMID: 27385266
Journal: Neurogastroenterol Motil. 2017 Sep;29(9).
Title: NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons.
Author: Vaes, N|Lentjes, M H F M|Gijbels, M J|Rademakers, G|Daenen, K L|Boesmans, W|Wouters, K A D|Geuzens, A|Qu, X|Steinbusch, H P J|Rutten, B P F|Baldwin, S H|Sharkey, K A|Hofstra, R M W|van Engeland, M|Vanden Berghe, P|Melotte, V
PMID: 28524415
Journal: Oncotarget. 2017 Dec 11;8(69):114183-114194.
Title: Identification and validation of colorectal neoplasia-specific methylation biomarkers based on CTCF-binding sites.
Author: Liu, Jiang|Ding, Zhaoli|Li, Guimei|Tang, Li|Xu, Yu|Luo, Huayou|Yi, Jinhua|Lu, Youwang|Mao, Rui|Nan, Qiong|Ren, Li|Zhang, Tong|Wang, Kunhua
PMID: 29371978
Journal: Intest Res. 2017 Oct;15(4):495-501.
Title: Is methylation analysis of SFRP2, TFPI2, NDRG4, and BMP3 promoters suitable for colorectal cancer screening in the Korean population?
Author: Park, Soo-Kyung|Baek, Hae Lim|Yu, Junghee|Kim, Ji Yeon|Yang, Hyo-Joon|Jung, Yoon Suk|Choi, Kyu Yong|Kim, Hungdai|Kim, Hyung Ook|Jeong, Kyung Uk|Chun, Ho-Kyung|Kim, Kyungeun|Park, Dong Il
PMID: 29142517
Journal: Gene. 2017 Sep 30;630:1-7.
Title: DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.
Author: Li, Jinyun|Chen, Cheng|Bi, Xuer|Zhou, Chongchang|Huang, Tao|Ni, Chao|Yang, Ping|Chen, Si|Ye, Meng|Duan, Shiwei
PMID: 28782576
Journal: Dig Dis Sci. 2017 Mar;62(3):678-688.
Title: Genetic Biomarker Prevalence Is Similar in Fecal Immunochemical Test Positive and Negative Colorectal Cancer Tissue.
Author: Levin, Theodore R|Corley, Douglas A|Jensen, Christopher D|Marks, Amy R|Zhao, Wei K|Zebrowski, Alexis M|Quinn, Virginia P|Browne, Lawrence W|Taylor, William R|Ahlquist, David A|Lidgard, Graham P|Berger, Barry M
PMID: 28044229
Journal: Scand J Gastroenterol. 2018 Mar;53(3):273-278.
Title: Multi-target stool DNA test in the surveillance of inflammatory bowel disease: a cross-sectional cohort study.
Author: Klepp, Pasquale|Kisiel, John B|Smastuen, Milada Cvancarova|Roseth, Arne|Andersen, Solveig N|Vatn, Morten H|Ahlquist, David A|Moum, Bjorn A|Brackmann, Stephan
PMID: 29313389
Journal: Clin Gastroenterol Hepatol. 2018 May 15. pii: S1542-3565(18)30490-7.
Title: Analysis of DNA Methylation at Specific Loci in Stool Samples Detects Colorectal Cancer and High-grade Dysplasia in Patients with Inflammatory Bowel Disease.
Author: Kisiel, John B|Klepp, Pasquale|Allawi, Hatim T|Taylor, William R|Giakoumopoulos, Maria|Sander, Tamara|Yab, Tracy C|Moum, Bjorn A|Lidgard, Graham P|Brackmann, Stephan|Mahoney, Douglas W|Roseth, Arne|Ahlquist, David A
PMID: 29775793
Journal: PLoS One. 2018 Jul 19;13(7):e0200735.
Title: The importance of stool DNA methylation in colorectal cancer diagnosis: A meta-analysis.
Author: Mojtabanezhad Shariatpanahi, Afsaneh|Yassi, Maryam|Nouraie, Mehdi|Sahebkar, Amirhossein|Varshoee Tabrizi, Fatemeh|Kerachian, Mohammad Amin
PMID: 30024936
Journal: Biochim Biophys Acta Gen Subj. 2018 Jul 7;1862(10):2140-2151.
Title: A combined literature and in silico analysis enlightens the role of the NDRG family in the gut.
Author: Vaes, Nathalie|Schonkeren, Simone L|Brosens, Erwin|Koch, Alexander|McCann, Conor J|Thapar, Nikhil|Hofstra, Robert M W|van Engeland, Manon|Melotte, Veerle
PMID: 30033230
Journal: Sci Adv. 2018 Sep 28;4(9):eaat6459.
Title: Facile profiling of molecular heterogeneity by microfluidic digital melt.
Author: O'Keefe, Christine M|Pisanic, Thomas R 2nd|Zec, Helena|Overman, Michael J|Herman, James G|Wang, Tza-Huei
PMID: 30263958