Primary Site >> Colorectal Cancer

Gene >> NDRG1

Journal: Cancer Res. 1998 May 15;58(10):2182-9.
Title: Cap43, a novel gene specifically induced by Ni2+ compounds.
Author: Zhou, D|Salnikow, K|Costa, M
PMID: 9605764
Journal: World J Gastroenterol. 2004 Feb 15;10(4):550-4.
Title: Correlation of N-myc downstream-regulated gene 1 overexpression with progressive growth of colorectal neoplasm.
Author: Wang, Zhen|Wang, Fang|Wang, Wei-Qi|Gao, Qian|Wei, Wan-Li|Yang, Yun|Wang, Guo-Ying
PMID: 14966915
Journal: Zhonghua Bing Li Xue Za Zhi. 2004 Jun;33(3):264-5.
Title: [Expression of NDRG1 gene in the progression of colorectal cancer and its relation to lymphatic metastasis].
Author: Wang, Zheng|Wang, Fan|Wei, Wan-li|Gao, Qie|Yang, Yun|Wang, Gao-ying
PMID: 15256124
Journal: Int J Oncol. 2005 Dec;27(6):1727-36.
Title: Differential gene expression of sulindac-treated human breast epithelial cells.
Author: Roy, D|Panda, A|Calaf, G M|Mitra, A
PMID: 16273229
Journal: World J Gastroenterol. 2007 May 28;13(20):2803-10.
Title: Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.
Author: Koshiji, Minori|Kumamoto, Kensuke|Morimura, Keiichirou|Utsumi, Yasufumi|Aizawa, Michiko|Hoshino, Masami|Ohki, Shinji|Takenoshita, Seiichi|Costa, Max|Commes, Therese|Piquemal, David|Harris, Curtis-C|Tchou-Wong, Kam-Meng
PMID: 17569115
Journal: Cancer Lett. 2008 Aug 8;266(2):171-85.
Title: Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer.
Author: Ummanni, Ramesh|Junker, Heike|Zimmermann, Uwe|Venz, Simone|Teller, Steffen|Giebel, Jurgen|Scharf, Christian|Woenckhaus, Christian|Dombrowski, Frank|Walther, Reinhard
PMID: 18384941
Journal: Ann Surg Oncol. 2009 May;16(5):1287-94.
Title: Identification of high-risk stage II colorectal tumors by combined analysis of the NDRG1 gene expression and the depth of tumor invasion.
Author: Strzelczyk, Barbara|Szulc, Aneta|Rzepko, Robert|Kitowska, Agnieszka|Skokowski, Jaroslaw|Szutowicz, Andrzej|Pawelczyk, Tadeusz
PMID: 19259744
Journal: Carcinogenesis. 2010 Aug;31(8):1381-6.
Title: Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.
Author: Frank, Bernd|Hoffmeister, Michael|Klopp, Norman|Illig, Thomas|Chang-Claude, Jenny|Brenner, Hermann
PMID: 20403915
Journal: Clin Exp Metastasis. 2011 Feb;28(2):127-35.
Title: Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620.
Author: Li, Qian|Chen, Hong
PMID: 21184144
Journal: J Biomed Biotechnol. 2012;2012:256178.
Title: The indolic diet-derivative, 3,3'-diindolylmethane, induced apoptosis in human colon cancer cells through upregulation of NDRG1.
Author: Lerner, A|Grafi-Cohen, M|Napso, T|Azzam, N|Fares, F
PMID: 22187533
Journal: Oncology. 2012;82(3):153-64.
Title: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author: Fernandez-Marcelo, Tamara|Moran, Alberto|de Juan, Carmen|Pascua, Irene|Head, Jacqueline|Gomez, Ana|Hernando, Florentino|Lopez-Asenjo, Jose A|Hernandez, Susana|Sanchez-Pernaute, Andres|Torres, Antonio J|Benito, Manuel|Iniesta, Pilar
PMID: 22433385
Journal: PLoS One. 2013 Jul 9;8(7):e68206.
Title: The metastasis suppressor, N-myc downregulated gene 1 (NDRG1), is a prognostic biomarker for human colorectal cancer.
Author: Mao, Zhihai|Sun, Jing|Feng, Bo|Ma, Junjun|Zang, Lu|Dong, Feng|Zhang, Daohai|Zheng, Minhua
PMID: 23874544
Journal: Biochem Biophys Res Commun. 2013 Sep 20;439(2):241-6.
Title: Correlation of N-myc downstream-regulated gene 1 subcellular localization and lymph node metastases of colorectal neoplasms.
Author: Song, Yan|Lv, Liyang|Du, Juan|Yue, Longtao|Cao, Lili
PMID: 23973486
Journal: J Cell Sci. 2014 Jul 15;127(Pt 14):3116-30.
Title: The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of beta-catenin through mechanisms involving FRAT1 and PAK4.
Author: Jin, Runsen|Liu, Wensheng|Menezes, Sharleen|Yue, Fei|Zheng, Minhua|Kovacevic, Zaklina|Richardson, Des R
PMID: 24829151
Journal: Curr Biol. 2015 Feb 2;25(3):296-305.
Title: NDR functions as a physiological YAP1 kinase in the intestinal epithelium.
Author: Zhang, Lei|Tang, Fengyuan|Terracciano, Luigi|Hynx, Debby|Kohler, Reto|Bichet, Sandrine|Hess, Daniel|Cron, Peter|Hemmings, Brian A|Hergovich, Alexander|Schmitz-Rohmer, Debora
PMID: 25601544
Journal: Eur Rev Med Pharmacol Sci. 2015 Nov;19(22):4275-84.
Title: Bioinformatic analysis of potential candidates for therapy of inflammatory bowel disease.
Author: Li, X L|Zhou, C Y|Sun, Y|Su, Z Y|Wang, X|N Jia, E|Zhang, Q|Jiang, X F|Qi, W Q|Xu, Y
PMID: 26636514
Journal: Oncotarget. 2015 Nov 10;6(35):37511-25.
Title: Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
Author: Talarico, Cristina|D'Antona, Lucia|Scumaci, Domenica|Barone, Agnese|Gigliotti, Francesco|Fiumara, Claudia Vincenza|Dattilo, Vincenzo|Gallo, Enzo|Visca, Paolo|Ortuso, Francesco|Abbruzzese, Claudia|Botta, Lorenzo|Schenone, Silvia|Cuda, Giovanni|Alcaro, Stef
PMID: 26462020
Journal: Oncotarget. 2015 Oct 20;6(32):33893-911.
Title: The metastasis suppressor, NDRG1, inhibits "stemness" of colorectal cancer via down-regulation of nuclear beta-catenin and CD44.
Author: Wangpu, Xiongzhi|Yang, Xiao|Zhao, Jingkun|Lu, Jiaoyang|Guan, Shaopei|Lu, Jun|Kovacevic, Zaklina|Liu, Wensheng|Mi, Lan|Jin, Runsen|Sun, Jing|Yue, Fei|Ma, Junjun|Lu, Aiguo|Richardson, Des R|Wang, Lishun|Zheng, Minhua
PMID: 26418878
Journal: Mol Pharmacol. 2016 May;89(5):521-40.
Title: Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
Author: Wangpu, Xiongzhi|Lu, Jiaoyang|Xi, Ruxing|Yue, Fei|Sahni, Sumit|Park, Kyung Chan|Menezes, Sharleen|Huang, Michael L H|Zheng, Minhua|Kovacevic, Zaklina|Richardson, Des R
PMID: 26895766
Journal: J Surg Oncol. 2016 Sep;114(4):520-7.
Title: Knockdown of NDRG1 promote epithelial-mesenchymal transition of colorectal cancer via NF-kappaB signaling.
Author: Ma, Junli|Gao, Quanli|Zeng, Shan|Shen, Hong
PMID: 27338835
Journal: Oncogene. 2017 Jul 27;36(30):4323-4335.
Title: The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells.
Author: Mi, L|Zhu, F|Yang, X|Lu, J|Zheng, Y|Zhao, Q|Wen, X|Lu, A|Wang, M|Zheng, M|Ji, J|Sun, J
PMID: 28346422
Journal: Zhonghua Bing Li Xue Za Zhi. 2017 Apr 8;46(4):240-244.
Title: [Expression characteristics of PTEN and NDRG1 in colorectal carcinoma and their prognostic value].
Author: Zhang, G X|Qian, Z Y|Yang, L J|Wang, F|Shen, H
PMID: 28376589
Journal: Oncotarget. 2017 Jul 18;8(29):47709-47724.
Title: N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2.
Author: Yang, Xiao|Zhu, Fan|Yu, Chaoran|Lu, Jiaoyang|Zhang, Luyang|Lv, Yanfeng|Sun, Jing|Zheng, Minhua
PMID: 28537875
Journal: Oncotarget. 2017 Jul 28;8(47):82593-82608.
Title: N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4.
Author: Zhang, Xian|Feng, Bo|Zhu, Fan|Yu, Chaoran|Lu, Jiaoyang|Pan, Meng|He, Zirui|Wangpu, Xiongzhi|Sun, Jing|Yang, Xiao
PMID: 29137287
Journal: BMC Cancer. 2018 May 25;18(1):594.
Title: Identification of genes inducing resistance to ionizing radiation in human rectal cancer cell lines: re-sensitization of radio-resistant rectal cancer cells through down regulating NDRG1.
Author: Kim, Soon-Chan|Shin, Young-Kyoung|Kim, Ye-Ah|Jang, Sang-Geun|Ku, Ja-Lok
PMID: 29801473
Journal: Biochim Biophys Acta Gen Subj. 2018 Jul 7;1862(10):2140-2151.
Title: A combined literature and in silico analysis enlightens the role of the NDRG family in the gut.
Author: Vaes, Nathalie|Schonkeren, Simone L|Brosens, Erwin|Koch, Alexander|McCann, Conor J|Thapar, Nikhil|Hofstra, Robert M W|van Engeland, Manon|Melotte, Veerle
PMID: 30033230
Journal: Medicine (Baltimore). 2018 Oct;97(41):e12455.
Title: The prognostic value of decreased NDRG1 expression in patients with digestive system cancers: A meta-analysis.
Author: Chen, Kang|Liu, Xiao-Hong|Wang, Fu-Rong|Liu, Hai-Peng|Huang, Ze-Ping|Chen, Xiao
PMID: 30313035
Journal: Biochem Biophys Res Commun. 2018 Oct 16. pii: S0006-291X(18)32200-9.
Title: Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/beta-catenin pathway in colon cancer cells.
Author: Chen, Zhiqiang|Sun, Jing|Li, Tao|Liu, Yanfeng|Gao, Shang|Zhi, Xuting|Zheng, Minhua
PMID: 30340826