Primary Site >> Liver Cancer

Gene >> NAT2

Journal: Biochem J. 1993 Sep 1;294 ( Pt 2):481-6.
Title: Arylamine N-acetyltransferase activity in human cultured cell lines.
Author: Coroneos, E|Sim, E
PMID: 8396914
Journal: Environ Health Perspect. 1997 Jun;105 Suppl 4:749-54.
Title: Interaction between dose and susceptibility to environmental cancer: a short review.
Author: Hietanen, E|Husgafvel-Pursiainen, K|Vainio, H
PMID: 9255556
Journal: Recent Results Cancer Res. 1998;154:47-85.
Title: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Author: Hengstler, J G|Arand, M|Herrero, M E|Oesch, F
PMID: 10026993
Journal: Toxicol Lett. 2000 Sep 30;117(1-2):69-77.
Title: Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene.
Author: Chen, R M|Chou, M W|Ueng, T H
PMID: 11033235
Journal: Gut. 2000 Nov;47(5):703-9.
Title: Role of N-acetyltransferase polymorphisms in hepatitis B related hepatocellular carcinoma: impact of smoking on risk.
Author: Yu, M W|Pai, C I|Yang, S Y|Hsiao, T J|Chang, H C|Lin, S M|Liaw, Y F|Chen, P J|Chen, C J
PMID: 11034589
Journal: IARC Sci Publ. 2001;154:241-4.
Title: Hepatocellular carcinoma: susceptibility markers.
Author: Blum, H E
PMID: 11220663
Journal: Scand J Gastroenterol. 2002 Jan;37(1):99-103.
Title: N-acetyltransferase 2 polymorphism is not related to the risk of advanced alcoholic liver disease.
Author: Agundez, J A G|Ladero, J M|Olivera, M|Lozano, L|Fernandez-Arquero, M|de laConcha, E G|Diaz-Rubio, M|Benitez, J
PMID: 11858170
Journal: Int J Clin Pharmacol Ther. 2002 Mar;40(3):120-4.
Title: Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients in a department of surgical medicine--a pilot investigation.
Author: Farker, K|Schotte, U|Scheele, J|Hoffmann, A
PMID: 11911601
Journal: Therapie. 2002 Sep-Oct;57(5):427-31.
Title: [Clinical relevance of N-acetyltransferase type 2 (NAT2) genetic polymorphism].
Author: Furet, Y|Bechtel, Y|Le Guellec, C|Bechtel, P R|Autret-Leca, E|Paintaud, G
PMID: 12611196
Journal: Am J Gastroenterol. 2003 Jun;98(6):1417-22.
Title: Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma.
Author: Huang, Yi-Shin|Chern, Herng-Der|Wu, Jaw-Ching|Chao, Yee|Huang, Yi-Hsiang|Chang, Full-Young|Lee, Shou-Dong
PMID: 12818290
Journal: Exp Toxicol Pathol. 2003 Jun;54(5-6):387-91.
Title: Impact of N-acetyltransferase polymorphism (NAT2) in hepatocellular carcinoma (HCC)--an investigation in a department of surgical medicine.
Author: Farker, Katrin|Schotte, Uwe|Scheele, Johannes|Hoffmann, Annemarie
PMID: 12877350
Journal: Indian J Exp Biol. 2003 Nov;41(11):1226-32.
Title: Antituberculosis drug-induced hepatitis: risk factors, prevention and management.
Author: Hussain, Z|Kar, P|Husain, S A
PMID: 15332488
Journal: World J Gastroenterol. 2005 Mar 14;11(10):1457-62.
Title: Are polymorphisms of N-acetyltransferase genes susceptible to primary liver cancer in Luoyang, China?
Author: Zhang, Xiu-Feng|Bian, Jian-Chao|Zhang, Xiao-Yan|Zhang, Zhu-Mei|Jiang, Feng|Wang, Qi-Min|Wang, Qi-Jun|Cao, Yan-Yan|Tang, Bo-Ming
PMID: 15770721
Journal: Int J Cancer. 2005 Jun 10;115(2):301-6.
Title: N-Acetyltransferase-2, glutathione S-transferase M1 and T1 genetic polymorphisms, cigarette smoking and hepatocellular carcinoma: a case-control study.
Author: Gelatti, Umberto|Covolo, Loredana|Talamini, Renato|Tagger, Alessandro|Barbone, Fabio|Martelli, Claudia|Cremaschini, Francesca|Franceschi, Silvia|Ribero, Maria Lisa|Garte, Seymour|Nardi, Giuseppe|Donadon, Valter|Donato, Francesco
PMID: 15688397
Journal: Biomarkers. 2007 Jan-Feb;12(1):21-37.
Title: Comparison of biomarkers in workers exposed to 2,4,6-trinitrotoluene.
Author: Sabbioni, G|Sepai, O|Norppa, H|Yan, H|Hirvonen, A|Zheng, Y|Jarventaus, H|Back, B|Brooks, L R|Warren, S H|Demarini, D M|Liu, Y Y
PMID: 17438651
Journal: Carcinogenesis. 2009 Oct;30(10):1729-34.
Title: Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population.
Author: Imaizumi, Takeshi|Higaki, Yasuki|Hara, Megumi|Sakamoto, Tatsuhiko|Horita, Mikako|Mizuta, Toshihiko|Eguchi, Yuichiro|Yasutake, Tsutomu|Ozaki, Iwata|Yamamoto, Kyosuke|Onohara, Shingo|Kawazoe, Seiji|Shigematsu, Hirohisa|Koizumi, Shunzo|Kudo, Sho|Tanaka, Keit
PMID: 19643819
Journal: Drug Metab Dispos. 2009 Nov;37(11):2123-6.
Title: Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
Author: Metry, Kristin J|Neale, Jason R|Bendaly, Jean|Smith, Ned B|Pierce, William M Jr|Hein, David W
PMID: 19666988
Journal: Tumour Biol. 2012 Aug;33(4):1059-63.
Title: Joint effect of polymorphism in the N-acetyltransferase 2 gene and smoking on hepatocellular carcinoma.
Author: Zhang, Jie|Xu, Feng|Ouyang, Chunhui
PMID: 22293947
Journal: Environ Mol Mutagen. 2012 Jun;53(5):350-7.
Title: Influence of arylamine N-acetyltransferase, sex, and age on 4-aminobiphenyl-induced in vivo mutant frequencies and spectra in mouse liver.
Author: Wang, Shuang|Sugamori, Kim S|Brenneman, Debbie|Hsu, Ivy|Calce, Adriana|Grant, Denis M
PMID: 22508569
Journal: Asian Pac J Cancer Prev. 2012;13 Suppl:7-15.
Title: Genetic polymorphism of drug metabolizing enzymes in association with risk of bile duct cancer.
Author: Kukongviriyapan, Veerapol
PMID: 23480767
Journal: J Proteome Res. 2014 Aug 1;13(8):3645-54.
Title: Large-scale proteome quantification of hepatocellular carcinoma tissues by a three-dimensional liquid chromatography strategy integrated with sample preparation.
Author: Xu, Bo|Wang, Fangjun|Song, Chunxia|Sun, Zhen|Cheng, Kai|Tan, Yexiong|Wang, Hongyang|Zou, Hanfa
PMID: 24972180
Journal: Drug Metab Dispos. 2015 Jul;43(7):916-21.
Title: Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice.
Author: Wang, Shuang|Bott, Debbie|Tung, Aveline|Sugamori, Kim S|Grant, Denis M
PMID: 25922528
Journal: J Gastrointest Oncol. 2016 Aug;7(4):570-9.
Title: A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
Author: Mok, Shaffer R S|Mohan, Sachin|Grewal, Navjot|Elfant, Adam B|Judge, Thomas A
PMID: 27563447
Journal: Br J Cancer. 2017 Sep 26;117(7):965-973.
Title: Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
Author: Levi, Francis|Karaboue, Abdoulaye|Saffroy, Raphael|Desterke, Christophe|Boige, Valerie|Smith, Denis|Hebbar, Mohamed|Innominato, Pasquale|Taieb, Julien|Carvalho, Carlos|Guimbaud, Rosine|Focan, Christian|Bouchahda, Mohamed|Adam, Rene|Ducreux, Michel|Milano,
PMID: 28817838
Journal: J Cancer. 2018 Apr 6;9(8):1506-1517.
Title: The Interaction of Smoking with Gene Polymorphisms on Four Digestive Cancers: A Systematic Review and Meta-Analysis.
Author: Du, Le|Lei, Lei|Zhao, Xiaojuan|He, Hongjuan|Chen, Erfei|Dong, Jing|Zeng, Yuan|Yang, Jin
PMID: 29721061
Journal: Oncol Lett. 2018 Jun;15(6):9625-9632.
Title: Screening therapeutic targets of ribavirin in hepatocellular carcinoma.
Author: Xu, Chen|Luo, Liyun|Yu, Yongjun|Zhang, Zhao|Zhang, Yi|Li, Haimei|Cheng, Yue|Qin, Hai|Zhang, Xipeng|Ma, Hongmei|Li, Yuwei
PMID: 29805683