Primary Site >> Biliary tract Cancer

Gene >> MYC

Journal: Hum Pathol. 1989 Dec;20(12):1163-8.
Title: Oncogene expression in cholangiocarcinoma and in normal hepatic development.
Author: Voravud, N|Foster, C S|Gilbertson, J A|Sikora, K|Waxman, J
PMID: 2574140
Journal: Hum Pathol. 1993 Jan;24(1):37-40.
Title: Expression of oncogene products and growth factors in early gallbladder cancer, advanced gallbladder cancer, and chronic cholecystitis.
Author: Yukawa, M|Fujimori, T|Hirayama, D|Idei, Y|Ajiki, T|Kawai, K|Sugiura, R|Maeda, S|Nagasako, K
PMID: 8093356
Journal: Rev Med Chil. 1994 Jul;122(7):754-9.
Title: [Gallbladder carcinoma: expression of the c-myc and ras-p-21 oncogene products].
Author: Roa, I|Araya, J C|Shiraishi, T|Yatani, R|Wistuba, I|Villaseca, M|de Aretxabala, X
PMID: 7732224
Journal: Pathol Int. 1996 Oct;46(10):764-70.
Title: Expression of apoptosis, proliferating cell nuclear antigen, and apoptosis-related antigens (bcl-2, c-myc, Fas, Lewis(y) and p53) in human cholangiocarcinomas and hepatocellular carcinomas.
Author: Terada, T|Nakanuma, Y
PMID: 8916146
Journal: Int J Cancer. 2003 Mar 10;104(1):44-53.
Title: Effects of E-cadherin transfection on gene expression of a gallbladder carcinoma cell line: repression of MTS1/S100A4 gene expression.
Author: Kohya, Naohiko|Kitajima, Yoshihiko|Jiao, Wan|Miyazaki, Kohji
PMID: 12532418
Journal: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2003 Mar;20(1):68-70.
Title: [The roles of VEGF and C-myc in occurrence, development and metastasis of gallbladder carcinoma].
Author: Liu, Zhimin|Jiang, Lili|Yang, Bin|Liao, Dianying
PMID: 12744166
Journal: Int J Oncol. 2005 Oct;27(4):973-80.
Title: Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas.
Author: Tokumoto, Noriaki|Ikeda, Satoshi|Ishizaki, Yasuyo|Kurihara, Takeshi|Ozaki, Shinji|Iseki, Masahiko|Shimizu, Yosuke|Itamoto, Toshiyuki|Arihiro, Koji|Okajima, Masazumi|Asahara, Toshimasa
PMID: 16142313
Journal: Zhong Yao Cai. 2005 Jun;28(6):489-91.
Title: [Research on resveratrol's effects on suppressing growth and inducing apoptosis of GBC cells].
Author: Sheng, Li|An, Lifeng|He, Ye|Fan, Guixiang|Yuan, Yukang
PMID: 16209266
Journal: Dig Surg. 2007;24(1):38-45. Epub 2007 Mar 16.
Title: Long-term survival after radical resection for pancreatic head and ampullary cancer: a potential role for the EGF-R.
Author: Smeenk, H G|Erdmann, J|van Dekken, H|van Marion, R|Hop, W C J|Jeekel, J|van Eijck, C H J
PMID: 17369680
Journal: Cancer Res. 2007 Oct 1;67(19):9006-12.
Title: FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Author: Akhoondi, Shahab|Sun, Dahui|von der Lehr, Natalie|Apostolidou, Sophia|Klotz, Kathleen|Maljukova, Alena|Cepeda, Diana|Fiegl, Heidi|Dafou, Dimitra|Marth, Christian|Mueller-Holzner, Elisabeth|Corcoran, Martin|Dagnell, Markus|Nejad, Sepideh Zabihi|Nayer, Baba
PMID: 17909001
Journal: Liver Int. 2007 Nov;27(9):1174-84.
Title: Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis.
Author: Itatsu, Keita|Zen, Yoh|Ohira, Shusaku|Ishikawa, Akira|Sato, Yasunori|Harada, Kenichi|Ikeda, Hiroko|Sasaki, Motoko|Nimura, Yuji|Nakanuma, Yasuni
PMID: 17919228
Journal: Hepatology. 2008 Mar;47(3):888-96.
Title: Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.
Author: Komori, Junji|Marusawa, Hiroyuki|Machimoto, Takafumi|Endo, Yoko|Kinoshita, Kazuo|Kou, Tadayuki|Haga, Hironori|Ikai, Iwao|Uemoto, Shinji|Chiba, Tsutomu
PMID: 18306229
Journal: Virchows Arch. 2008 Dec;453(6):579-88.
Title: Immunophenotyping and oncogene amplifications in tumors of the papilla of Vater.
Author: Baumhoer, Daniel|Zlobec, Inti|Tornillo, Luigi|Dietmaier, Wolfgang|Wuensch, Peter H|Hartmann, Arndt|Sessa, Fausto|Ruemmele, Petra|Terracciano, Luigi M
PMID: 18936968
Journal: Anticancer Res. 2009 Jan;29(1):19-26.
Title: Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma.
Author: Ooi, Akishi|Suzuki, Shioto|Nakazawa, Kumiko|Itakura, Jun|Imoto, Issei|Nakamura, Hiroyuki|Dobashi, Yoh
PMID: 19331129
Journal: World J Hepatol. 2009 Oct 31;1(1):35-42.
Title: Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts.
Author: Nakanuma, Yasuni|Sasaki, Motoko|Sato, Yasunori|Ren, Xiangshan|Ikeda, Hiroko|Harada, Kenichi
PMID: 21160963
Journal: Am J Surg. 2010 Apr;199(4):515-21.
Title: Overexpression of LAPTM4B promotes growth of gallbladder carcinoma cells in vitro.
Author: Zhou, Li|He, Xiao-Dong|Yu, Jian-Chun|Zhou, Rou-Li|Yang, Hua|Qu, Qiang|Rui, Jing-An
PMID: 19954766
Journal: Dig Dis Sci. 2010 Oct;55(10):2844-52.
Title: The role of MAPK-ERK pathway in 67-kDa laminin receptor-induced FasL expression in human cholangiocarcinoma cells.
Author: Duan, Shi-Gang|Cheng, Long|Li, Da-Jiang|Zhu, Jin|Xiong, Yan|Li, Xiao-Wu|Wang, Shu-Guang
PMID: 20101459
Journal: Carcinogenesis. 2011 Sep;32(9):1372-80.
Title: Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways.
Author: Prakobwong, Suksanti|Gupta, Subash C|Kim, Ji Hye|Sung, Bokyung|Pinlaor, Porntip|Hiraku, Yusuke|Wongkham, Sopit|Sripa, Banchob|Pinlaor, Somchai|Aggarwal, Bharat B
PMID: 21325634
Journal: Cell Biol Int. 2011 Aug;35(8):799-802.
Title: Down-regulation of c-Myc expression inhibits the invasion of bile duct carcinoma cells.
Author: Li, Zhuo-Ri|Wu, Yi-Fei|Ma, Chun-Yang|Nie, Shen-Dan|Mao, Xian-Hai|Shi, Yong-Zhong
PMID: 21557726
Journal: Asian Pac J Cancer Prev. 2012;13 Suppl:155-60.
Title: TNP-470, a methionine aminopeptidase-2 inhibitor, inhibits cell proliferation, migration and invasion of human cholangiocarcinoma cells in vitro.
Author: Kidoikhammouan, Sonexai|Seubwai, Wunchana|Tantapotinan, Nattawat|Silsirivanit, Atit|Wongkham, Sopit|Sawanyawisuth, Kanlayanee|Wongkham, Chaisiri
PMID: 23480758
Journal: Gastroenterology. 2012 Jul;143(1):246-56.e8.
Title: MicroRNA-26a promotes cholangiocarcinoma growth by activating beta-catenin.
Author: Zhang, Jinqiang|Han, Chang|Wu, Tong
PMID: 22484120
Journal: FEBS Lett. 2012 Sep 21;586(19):3271-8.
Title: Epigenetic regulation of miR-124 by hepatitis C virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3.
Author: Zeng, Bing|Li, Zhihua|Chen, Rufu|Guo, Ning|Zhou, Jiajia|Zhou, Quanbo|Lin, Qing|Cheng, Di|Liao, Qiaofang|Zheng, Liping|Gong, Yuanfeng
PMID: 22819820
Journal: J Dig Dis. 2013 Jan;14(1):45-50.
Title: Xanthogranulomatous cholecystitis: a clinicopathological study of its association with gallbladder carcinoma.
Author: Zhuang, Peng Yuan|Zhu, Ming Jie|Wang, Jian Dong|Zhou, Xue Ping|Quan, Zhi Wei|Shen, Jun
PMID: 23134201
Journal: PLoS One. 2013 Apr 30;8(4):e62844.
Title: Suppression of cholangiocarcinoma cell growth by human umbilical cord mesenchymal stem cells: a possible role of Wnt and Akt signaling.
Author: Liu, Juan|Han, Guoqing|Liu, Hui|Qin, Chengyong
PMID: 23646150
Journal: Oncol Rep. 2013 Sep;30(3):1430-8.
Title: Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells.
Author: Zhang, Kun-Song|Zhou, Qi|Wang, Ya-Feng|Liang, Li-Jian
PMID: 23799613
Journal: Int J Oncol. 2014 Aug;45(2):691-8.
Title: The role of nuclear EpICD in extrahepatic cholangiocarcinoma: association with beta-catenin.
Author: Jachin, Sarangerel|Bae, Jun Sang|Sung, Jong Jin|Park, Ho Sung|Jang, Kyu Yun|Chung, Myoung Ja|Kim, Dae Gohn|Moon, Woo Sung
PMID: 24888903
Journal: Mol Cancer. 2014 Jun 23;13:156.
Title: Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer.
Author: Ma, Ming-Zhe|Li, Chun-Xiao|Zhang, Yan|Weng, Ming-Zhe|Zhang, Ming-di|Qin, Yi-Yu|Gong, Wei|Quan, Zhi-Wei
PMID: 24953832
Journal: Cancer Res. 2015 Apr 1;75(7):1388-98.
Title: Omega-3 Polyunsaturated Fatty Acids Upregulate 15-PGDH Expression in Cholangiocarcinoma Cells by Inhibiting miR-26a/b Expression.
Author: Yao, Lu|Han, Chang|Song, Kyoungsub|Zhang, Jinqiang|Lim, Kyu|Wu, Tong
PMID: 25691459
Journal: PLoS One. 2015 Aug 19;10(8):e0136193.
Title: Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling.
Author: Zhang, Peng|Guo, Zhiyong|Wu, Ying|Hu, Ronglin|Du, Jun|He, Xiaoshun|Jiao, Xingyuan|Zhu, Xiaofeng
PMID: 26287365
Journal: Oncotarget. 2015 Oct 20;6(32):33065-76.
Title: Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer.
Author: Lian, Shi Xian|Shao, Ye Bo|Liu, Hou Bao|He, Jun Yi|Lu, Wei Qi|Zhang, Yong|Jiang, Ying|Zhu, Jun
PMID: 26460616
Journal: Clin Transl Oncol. 2016 Sep;18(9):878-83.
Title: SATB1 is a potential therapeutic target in intrahepatic cholangiocarcinoma.
Author: Zhao, Z|Ma, J|Wu, K|Chen, L|Yu, J|Hu, W|Zhang, K
PMID: 26563145
Journal: Hepatology. 2016 Aug;64(2):336-9.
Title: New molecular interactions of c-Myc in cholangiocarcinoma may open new therapeutic opportunities.
Author: Berasain, Carmen|Fernandez-Barrena, Maite G|Avila, Matias A
PMID: 27102840
Journal: Eur J Histochem. 2016 Feb 9;60(1):2536.
Title: Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach.
Author: Chen, W|Liang, J|Huang, L|Cai, J|Lei, Y|Lai, J|Liang, L|Zhang, K
PMID: 26972709
Journal: Hepatology. 2016 Aug;64(2):439-55.
Title: Deregulated methionine adenosyltransferase alpha1, c-Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans(double dagger).
Author: Yang, Heping|Liu, Ting|Wang, Jiaohong|Li, Tony W H|Fan, Wei|Peng, Hui|Krishnan, Anuradha|Gores, Gregory J|Mato, Jose M|Lu, Shelly C
PMID: 26969892
Journal: Gut. 2016 Oct;65(10):1765-75.
Title: LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Author: Scarzello, Anthony J|Jiang, Qun|Back, Timothy|Dang, Hien|Hodge, Deborah|Hanson, Charlotte|Subleski, Jeffrey|Weiss, Jonathan M|Stauffer, Jimmy K|Chaisaingmongkol, Jitti|Rabibhadana, Siritida|Ruchirawat, Mathuros|Ortaldo, John|Wang, Xin Wei|Norris, Paula S|
PMID: 26206664
Journal: Hepatology. 2017 Apr;65(4):1249-1266.
Title: Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells.
Author: Fan, Wei|Yang, Heping|Liu, Ting|Wang, Jiaohong|Li, Tony W H|Mavila, Nirmala|Tang, Yuanyuan|Yang, JinWon|Peng, Hui|Tu, Jian|Annamalai, Alagappan|Noureddin, Mazen|Krishnan, Anuradha|Gores, Gregory J|Martinez-Chantar, Maria L|Mato, Jose M|Lu, Shelly C
PMID: 27981602
Journal: Oncol Rep. 2017 Mar;37(3):1627-1636.
Title: E3 ubiquitin ligase FBW7alpha inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.
Author: Li, Ming|Ouyang, Ling|Zheng, Zhigang|Xiang, Dan|Ti, Aijun|Li, Leihua|Dan, Yuzhen|Yu, Chundong|Li, Wengang
PMID: 28184929
Journal: Cell Physiol Biochem. 2017;42(1):222-230.
Title: Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in Cholangiocarcinoma.
Author: Lu, Xu|Zhou, Chuang|Li, Renfeng|Deng, Yilei|Zhao, Longshuan|Zhai, Wenlong
PMID: 28535506
Journal: Cancer Sci. 2018 May;109(5):1532-1544.
Title: The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer.
Author: Li, Huaifeng|Jin, Yunpeng|Hu, Yunping|Jiang, Lin|Liu, Fatao|Zhang, Yijian|Hao, Yajuan|Chen, Shili|Wu, Xiangsong|Liu, Yingbin
PMID: 29575299
Journal: Gastroenterology. 2018 Aug;155(2):557-571.e14.
Title: Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.
Author: Liu, Ting|Yang, Heping|Fan, Wei|Tu, Jian|Li, Tony W H|Wang, Jiaohong|Shen, Hong|Yang, JinWon|Xiong, Ting|Steggerda, Justin|Liu, Zhenqiu|Noureddin, Mazen|Maldonado, Stephanie S|Annamalai, Alagappan|Seki, Ekihiro|Mato, Jose M|Lu, Shelly C
PMID: 29733835
Journal: Cancer Sci. 2018 Aug 28.
Title: Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1.
Author: Fujiwara, Hiroaki|Tateishi, Keisuke|Kato, Hiroyuki|Nakatsuka, Takuma|Yamamoto, Keisuke|Tanaka, Yasuo|Ijichi, Hideaki|Takahara, Naminatsu|Mizuno, Suguru|Kogure, Hirofumi|Matsubara, Saburo|Nakai, Yousuke|Koike, Kazuhiko
PMID: 30156013
Journal: Biochem Biophys Res Commun. 2018 Sep 8. pii: S0006-291X(18)31868-0.
Title: Long non-coding RNA EPIC1 promotes cholangiocarcinoma cell growth.
Author: Li, Yong|Cai, Quanyu|Li, Wanhu|Feng, Feiling|Yang, Liang
PMID: 30205958
Journal: Cell Physiol Biochem. 2018 Sep 20;49(5):1933-1942.
Title: miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma.
Author: Kang, Peng-Cheng|Leng, Kai-Ming|Liu, Yue-Ping|Liu, Yang|Xu, Yi|Qin, Wei|Gao, Jian-Jun|Wang, Zhi-Dong|Tai, Sheng|Zhong, Xiang-Yu|Cui, Yun-Fu
PMID: 30235453