Primary Site >> Biliary tract Cancer
Gene >> MTOR
| 1. | |||||||||||
| Journal: | Am J Pathol. 2003 Jul;163(1):217-29. | ||||||||||
| Title: | Identification of novel cellular targets in biliary tract cancers using global gene expression technology. | ||||||||||
| Author: | Hansel, Donna E|Rahman, Ayman|Hidalgo, Manuel|Thuluvath, Paul J|Lillemoe, Keith D|Schulick, Richard|Ku, Ja-Lok|Park, Jae-Gahb|Miyazaki, Kohje|Ashfaq, Raheela|Wistuba, Ignacio I|Varma, Ram|Hawthorne, Lesleyann|Geradts, Joseph|Argani, Pedram|Maitra, Anirban | ||||||||||
| PMID: | 12819026 | ||||||||||
| 2. | |||||||||||
| Journal: | J Clin Invest. 2006 Jul;116(7):1843-52. Epub 2006 Jun 8. | ||||||||||
| Title: | Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. | ||||||||||
| Author: | Xu, Xiaoling|Kobayashi, Shogo|Qiao, Wenhui|Li, Cuiling|Xiao, Cuiying|Radaeva, Svetlana|Stiles, Bangyan|Wang, Rui-Hong|Ohara, Nobuya|Yoshino, Tadashi|LeRoith, Derek|Torbenson, Michael S|Gores, Gregory J|Wu, Hong|Gao, Bin|Deng, Chu-Xia | ||||||||||
| PMID: | 16767220 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2007 Apr 15;67(8):3794-800. | ||||||||||
| Title: | Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model. | ||||||||||
| Author: | Wu, Qi|Kiguchi, Kaoru|Kawamoto, Toru|Ajiki, Tetsuo|Traag, Jeanine|Carbajal, Steve|Ruffino, Lynnsie|Thames, Howard|Wistuba, Ignacio|Thomas, Melanie|Vasquez, Karen M|DiGiovanni, John | ||||||||||
| PMID: | 17440093 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Jan 15;15(2):660-7. | ||||||||||
| Title: | The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Chung, Joon-Yong|Hong, Seung-Mo|Choi, Byeong Yeob|Cho, Hyungjun|Yu, Eunsil|Hewitt, Stephen M | ||||||||||
| PMID: | 19147772 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Jun;8(6):1547-56. | ||||||||||
| Title: | Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells. | ||||||||||
| Author: | Herberger, Beata|Berger, Walter|Puhalla, Harald|Schmid, Katharina|Novak, Sabine|Brandstetter, Anita|Pirker, Christine|Gruenberger, Thomas|Filipits, Martin | ||||||||||
| PMID: | 19509244 | ||||||||||
| 6. | |||||||||||
| Journal: | HPB (Oxford). 2011 May;13(5):309-19. | ||||||||||
| Title: | Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma. | ||||||||||
| Author: | McKay, Siobhan C|Unger, Kristian|Pericleous, Stephanos|Stamp, Gordon|Thomas, Gerry|Hutchins, Robert R|Spalding, Duncan R C | ||||||||||
| PMID: | 21492330 | ||||||||||
| 7. | |||||||||||
| Journal: | Mod Pathol. 2012 Jan;25(1):131-9. | ||||||||||
| Title: | The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas. | ||||||||||
| Author: | Lee, Dakeun|Do, In-Gu|Choi, Kyusam|Sung, Chang Ohk|Jang, Kee-Taek|Choi, Dongwook|Heo, Jin Seok|Choi, Seoung Ho|Kim, Jongmin|Park, Jin Young|Cha, Hyung Jin|Joh, Jae-Won|Choi, Kwan Yong|Kim, Dae Shick | ||||||||||
| PMID: | 21874010 | ||||||||||
| 8. | |||||||||||
| Journal: | Neoplasma. 2012;59(2):137-41. | ||||||||||
| Title: | Immunohistochemical analysis of the mTOR pathway in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Wang, Z|Zheng, T|Wu, Q|Wang, J|Wu, C|Wang, J | ||||||||||
| PMID: | 22248270 | ||||||||||
| 9. | |||||||||||
| Journal: | Genome Med. 2012 Jul 4;4(7):56. | ||||||||||
| Title: | Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability. | ||||||||||
| Author: | Demeure, Michael J|Craig, David W|Sinari, Shripad|Moses, Tracy M|Christoforides, Alexis|Dinh, Jennifer|Izatt, Tyler|Aldrich, Jessica|Decker, Ardis|Baker, Angela|Cherni, Irene|Watanabe, April|Koep, Lawrence|Lake, Douglas|Hostetter, Galen|Trent, Jeffrey M|V | ||||||||||
| PMID: | 22762308 | ||||||||||
| 10. | |||||||||||
| Journal: | Tumour Biol. 2013 Dec;34(6):3637-48. | ||||||||||
| Title: | Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy. | ||||||||||
| Author: | Yothaisong, Supak|Dokduang, Hasaya|Techasen, Anchalee|Namwat, Nisana|Yongvanit, Puangrat|Bhudhisawasdi, Vajarabhongsa|Puapairoj, Anucha|Riggins, Gregory J|Loilome, Watcharin | ||||||||||
| PMID: | 23832540 | ||||||||||
| 11. | |||||||||||
| Journal: | Onco Targets Ther. 2013 Oct 3;6:1373-84. | ||||||||||
| Title: | AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines. | ||||||||||
| Author: | Leal, Pamela|Garcia, Patricia|Sandoval, Alejandra|Buchegger, Kurt|Weber, Helga|Tapia, Oscar|Roa, Juan C | ||||||||||
| PMID: | 24124380 | ||||||||||
| 12. | |||||||||||
| Journal: | Anticancer Res. 2013 May;33(5):1861-6. | ||||||||||
| Title: | Antiproliferative and apoptosis-inducing activity of curcumin against human gallbladder adenocarcinoma cells. | ||||||||||
| Author: | Ono, Misaki|Higuchi, Takako|Takeshima, Mikako|Chen, Chen|Nakano, Shuji | ||||||||||
| PMID: | 23645731 | ||||||||||
| 13. | |||||||||||
| Journal: | Arch Pathol Lab Med. 2013 Apr;137(4):552-7. | ||||||||||
| Title: | Immunohistochemical expression of phospho-mTOR is associated with poor prognosis in patients with gallbladder adenocarcinoma. | ||||||||||
| Author: | Leal, Pamela|Garcia, Patricia|Sandoval, Alejandra|Letelier, Pablo|Brebi, Priscilla|Ili, Carmen|Alvarez, Hector|Tapia, Oscar|Roa, Juan C | ||||||||||
| PMID: | 23544944 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Exp Metastasis. 2013 Feb;30(2):177-87. | ||||||||||
| Title: | Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma. | ||||||||||
| Author: | Hong, Sun Mi|Park, Chang Wook|Cha, Hyung Jin|Kwon, Jung Hee|Yun, Young Sung|Lee, Nam Gyu|Kim, Dae-Ghon|Nam, Hong Gil|Choi, Kwan Yong | ||||||||||
| PMID: | 22875246 | ||||||||||
| 15. | |||||||||||
| Journal: | Hepatology. 2013 Aug;58(2):810-8. | ||||||||||
| Title: | The mTOR pathway in hepatic malignancies. | ||||||||||
| Author: | Bhat, Mamatha|Sonenberg, Nahum|Gores, Gregory J | ||||||||||
| PMID: | 23408390 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Cancer. 2013 Nov;133(9):2065-76. | ||||||||||
| Title: | Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma. | ||||||||||
| Author: | Ewald, Florian|Grabinski, Nicole|Grottke, Astrid|Windhorst, Sabine|Norz, Dominik|Carstensen, Lisa|Staufer, Katharina|Hofmann, Bianca T|Diehl, Frank|David, Kerstin|Schumacher, Udo|Nashan, Bjorn|Jucker, Manfred | ||||||||||
| PMID: | 23588885 | ||||||||||
| 17. | |||||||||||
| Journal: | Cell Biochem Biophys. 2014 Nov;70(2):1337-42. | ||||||||||
| Title: | Phenoxodiol enhances the antitumor activity of gemcitabine in gallbladder cancer through suppressing Akt/mTOR pathway. | ||||||||||
| Author: | Li, Yu|Huang, Xiaoqiang|Huang, Zhiqiang|Feng, Jian | ||||||||||
| PMID: | 24902539 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2014 Dec 23;9(12):e115383. | ||||||||||
| Title: | Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. | ||||||||||
| Author: | Churi, Chaitanya R|Shroff, Rachna|Wang, Ying|Rashid, Asif|Kang, HyunSeon C|Weatherly, Jacqueline|Zuo, Mingxin|Zinner, Ralph|Hong, David|Meric-Bernstam, Funda|Janku, Filip|Crane, Christopher H|Mishra, Lopa|Vauthey, Jean-Nicholas|Wolff, Robert A|Mills, Gord | ||||||||||
| PMID: | 25536104 | ||||||||||
| 19. | |||||||||||
| Journal: | Semin Liver Dis. 2014 Nov;34(4):456-64. | ||||||||||
| Title: | Cholangiocarcinoma: molecular pathways and therapeutic opportunities. | ||||||||||
| Author: | Rizvi, Sumera|Borad, Mitesh J|Patel, Tushar|Gores, Gregory J | ||||||||||
| PMID: | 25369307 | ||||||||||
| 20. | |||||||||||
| Journal: | Invest New Drugs. 2014 Dec;32(6):1144-54. | ||||||||||
| Title: | Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors. | ||||||||||
| Author: | Ewald, Florian|Norz, Dominik|Grottke, Astrid|Hofmann, Bianca T|Nashan, Bjorn|Jucker, Manfred | ||||||||||
| PMID: | 25152244 | ||||||||||
| 21. | |||||||||||
| Journal: | Ann Oncol. 2014 Aug;25(8):1597-603. | ||||||||||
| Title: | Activity and safety of RAD001 (everolimus) in patients affected by biliary tract cancer progressing after prior chemotherapy: a phase II ITMO study. | ||||||||||
| Author: | Buzzoni, R|Pusceddu, S|Bajetta, E|De Braud, F|Platania, M|Iannacone, C|Cantore, M|Mambrini, A|Bertolini, A|Alabiso, O|Ciarlo, A|Turco, C|Mazzaferro, V | ||||||||||
| PMID: | 24827133 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2014 May 15;5(9):2372-89. | ||||||||||
| Title: | Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma. | ||||||||||
| Author: | Chen, Ming-Huang|Chiang, Kun-Chun|Cheng, Chi-Tung|Huang, Shih-Chiang|Chen, Yeng-Yang|Chen, Tsung-Wen|Yeh, Ta-Sen|Jan, Yi-Yin|Wang, Hsi-Ming|Weng, Jiang-Jie|Chang, Peter Mu-Hsin|Liu, Chun-Yu|Li, Chung-Pin|Chao, Yee|Chen, Ming-Han|Huang, Chi-Ying F|Yeh, Chu | ||||||||||
| PMID: | 24796583 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncol Rep. 2014 Jun;31(6):2611-8. | ||||||||||
| Title: | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | ||||||||||
| Author: | Ling, Sunbin|Feng, Tingting|Ke, Qinghong|Fan, Ning|Li, Lei|Li, Zhongxing|Dong, Chengyong|Wang, Cong|Xu, Fei|Li, Yan|Wang, Liming | ||||||||||
| PMID: | 24788596 | ||||||||||
| 24. | |||||||||||
| Journal: | Mol Biol Rep. 2014 Jul;41(7):4507-12. | ||||||||||
| Title: | Inhibition of mTOR pathway attenuates migration and invasion of gallbladder cancer via EMT inhibition. | ||||||||||
| Author: | Zong, Huajie|Yin, Baobing|Zhou, Huading|Cai, Duan|Ma, Baojin|Xiang, Yang | ||||||||||
| PMID: | 24623408 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Treat Rev. 2015 Mar;41(3):222-34. | ||||||||||
| Title: | Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy. | ||||||||||
| Author: | Bizama, Carolina|Garcia, Patricia|Espinoza, Jaime A|Weber, Helga|Leal, Pamela|Nervi, Bruno|Roa, Juan Carlos | ||||||||||
| PMID: | 25639632 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2015 Nov 16;10(11):e0142124. | ||||||||||
| Title: | Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures. | ||||||||||
| Author: | Fraveto, Alice|Cardinale, Vincenzo|Bragazzi, Maria Consiglia|Giuliante, Felice|De Rose, Agostino Maria|Grazi, Gian Luca|Napoletano, Chiara|Semeraro, Rossella|Lustri, Anna Maria|Costantini, Daniele|Nevi, Lorenzo|Di Matteo, Sabina|Renzi, Anastasia|Carpino, | ||||||||||
| PMID: | 26571380 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncotarget. 2015 Oct 13;6(31):31877-88. | ||||||||||
| Title: | Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice. | ||||||||||
| Author: | Weber, Helga|Leal, Pamela|Stein, Stefan|Kunkel, Hana|Garcia, Patricia|Bizama, Carolina|Espinoza, Jaime A|Riquelme, Ismael|Nervi, Bruno|Araya, Juan C|Grez, Manuel|Roa, Juan C | ||||||||||
| PMID: | 26397134 | ||||||||||
| 28. | |||||||||||
| Journal: | Diagn Pathol. 2015 Aug 21;10:148. | ||||||||||
| Title: | Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer. | ||||||||||
| Author: | Roa, Ivan|de Toro, Gonzalo|Fernandez, Fernanda|Game, Anakaren|Munoz, Sergio|de Aretxabala, Xabier|Javle, Milind | ||||||||||
| PMID: | 26294099 | ||||||||||
| 29. | |||||||||||
| Journal: | PLoS One. 2015 Aug 19;10(8):e0136193. | ||||||||||
| Title: | Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling. | ||||||||||
| Author: | Zhang, Peng|Guo, Zhiyong|Wu, Ying|Hu, Ronglin|Du, Jun|He, Xiaoshun|Jiao, Xingyuan|Zhu, Xiaofeng | ||||||||||
| PMID: | 26287365 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2015 Mar 20;6(8):6310-25. | ||||||||||
| Title: | FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells. | ||||||||||
| Author: | Yang, Hui|Lu, Xiaofei|Liu, Ziming|Chen, Lili|Xu, Yunfei|Wang, Yuli|Wei, Guangwei|Chen, Yuxin | ||||||||||
| PMID: | 25749036 | ||||||||||
| 31. | |||||||||||
| Journal: | Br J Cancer. 2015 Mar 17;112(6):1042-51. | ||||||||||
| Title: | Novel therapeutic strategy targeting the Hedgehog signalling and mTOR pathways in biliary tract cancer. | ||||||||||
| Author: | Zuo, M|Rashid, A|Churi, C|Vauthey, J-N|Chang, P|Li, Y|Hung, M-C|Li, D|Javle, M | ||||||||||
| PMID: | 25742482 | ||||||||||
| 32. | |||||||||||
| Journal: | Tumour Biol. 2015 Jul;36(7):5171-7. | ||||||||||
| Title: | Loss of angiotensin-converting enzyme 2 promotes growth of gallbladder cancer. | ||||||||||
| Author: | Zong, Huajie|Yin, Baobing|Zhou, Huading|Cai, Duan|Ma, Baojin|Xiang, Yang | ||||||||||
| PMID: | 25663464 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Lett. 2015 May 1;360(2):141-50. | ||||||||||
| Title: | Fibronectin promotes cell proliferation and invasion through mTOR signaling pathway activation in gallbladder cancer. | ||||||||||
| Author: | Cao, Yang|Liu, Xiyong|Lu, Wei|Chen, Yuanyuan|Wu, Xiangsong|Li, Maolan|Wang, Xu-An|Zhang, Fei|Jiang, Lin|Zhang, Yijian|Hu, Yunping|Xiang, Shanshan|Shu, Yijun|Bao, Runfa|Li, Huaifeng|Wu, Wenguang|Weng, Hao|Yen, Yun|Liu, Yingbin | ||||||||||
| PMID: | 25657110 | ||||||||||
| 34. | |||||||||||
| Journal: | Mol Clin Oncol. 2015 May;3(3):464-470. Epub 2015 Feb 25. | ||||||||||
| Title: | Expression of insulin-like growth factor I receptor as a biomarker for predicting prognosis in biliary tract cancer patients. | ||||||||||
| Author: | Suzuki, Hideo|Roa, Juan C|Kawamoto, Toru|Ishige, Kazunori|Wistuba, Ignacio I|Li, Donghui|Thomas, Melanie B|Shoda, Junichi | ||||||||||
| PMID: | 26137252 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncogenesis. 2016 Dec 5;5(12):e274. | ||||||||||
| Title: | Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans. | ||||||||||
| Author: | Che, L|Fan, B|Pilo, M G|Xu, Z|Liu, Y|Cigliano, A|Cossu, A|Palmieri, G|Pascale, R M|Porcu, A|Vidili, G|Serra, M|Dombrowski, F|Ribback, S|Calvisi, D F|Chen, X | ||||||||||
| PMID: | 27918553 | ||||||||||
| 36. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2016 May;20(9):1699-706. | ||||||||||
| Title: | Inhibition of mTOR suppresses human gallbladder carcinoma cell proliferation and enhances the cytotoxicity of 5-fluorouracil by downregulating MDR1 expression. | ||||||||||
| Author: | Li, Q|Mou, L-J|Tao, L|Chen, W|Sun, X-T|Xia, X-F|Wu, X-Y|Shi, X-L | ||||||||||
| PMID: | 27212159 | ||||||||||
| 37. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 29;7(13):17220-9. | ||||||||||
| Title: | Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Peng, Hong|Zhang, Qiuyang|Li, Jiali|Zhang, Ning|Hua, Yunpeng|Xu, Lixia|Deng, Yubin|Lai, Jiaming|Peng, Zhenwei|Peng, Baogang|Chen, Minhu|Peng, Sui|Kuang, Ming | ||||||||||
| PMID: | 26967384 | ||||||||||
| 38. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Feb 14;22(6):2071-80. | ||||||||||
| Title: | Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice. | ||||||||||
| Author: | Ding, Ning|Che, Li|Li, Xiao-Lei|Liu, Yan|Jiang, Li-Jie|Fan, Biao|Tao, Jun-Yan|Chen, Xin|Ji, Jia-Fu | ||||||||||
| PMID: | 26877611 | ||||||||||
| 39. | |||||||||||
| Journal: | J Gastroenterol. 2016 Jul;51(7):711-21. | ||||||||||
| Title: | A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks. | ||||||||||
| Author: | Mohri, Dai|Ijichi, Hideaki|Miyabayashi, Koji|Takahashi, Ryota|Kudo, Yotaro|Sasaki, Takashi|Asaoka, Yoshinari|Tanaka, Yasuo|Ikenoue, Tsuneo|Tateishi, Keisuke|Tada, Minoru|Isayama, Hiroyuki|Koike, Kazuhiko | ||||||||||
| PMID: | 26614007 | ||||||||||
| 40. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 17;8(3):5349-5360. | ||||||||||
| Title: | Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing. | ||||||||||
| Author: | Feng, Feiling|Cheng, Qingbao|Yang, Liang|Zhang, Dadong|Ji, Shunlong|Zhang, Qiangzu|Lin, Yihui|Li, Fugen|Xiong, Lei|Liu, Chen|Jiang, Xiaoqing | ||||||||||
| PMID: | 28029662 | ||||||||||
| 41. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 21;8(12):19980-19996. | ||||||||||
| Title: | SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressing Akt/mTOR signaling. | ||||||||||
| Author: | Qin, Yiyu|Meng, Li|Fu, Yang|Quan, Zhiwei|Ma, Mingzhe|Weng, Mingzhe|Zhang, Zhengdong|Gao, Cuixiang|Shi, Xinghua|Han, Koulan | ||||||||||
| PMID: | 28212545 | ||||||||||
| 42. | |||||||||||
| Journal: | Mol Oncol. 2017 Sep;11(9):1130-1142. | ||||||||||
| Title: | K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines. | ||||||||||
| Author: | Yeung, Yvonne|Lau, David K|Chionh, Fiona|Tran, Hoanh|Tse, Janson W T|Weickhardt, Andrew J|Nikfarjam, Mehrdad|Scott, Andrew M|Tebbutt, Niall C|Mariadason, John M | ||||||||||
| PMID: | 28544747 | ||||||||||
| 43. | |||||||||||
| Journal: | World J Gastroenterol. 2017 Jun 21;23(23):4311-4316. | ||||||||||
| Title: | Benefit of everolimus in treatment of an intrahepatic cholangiocarcinoma patient with a PIK3CA mutation. | ||||||||||
| Author: | Bian, Ji-Lai|Wang, Mei-Mei|Tong, En-Juan|Sun, Jing|Li, Ming|Miao, Zhi-Bo|Li, Yan-Lin|Zhu, Bai-Hong|Xu, Jia-Jia | ||||||||||
| PMID: | 28694672 | ||||||||||
| 44. | |||||||||||
| Journal: | J Hepatol. 2017 Dec;67(6):1194-1203. | ||||||||||
| Title: | Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. | ||||||||||
| Author: | Zhang, Shanshan|Song, Xinhua|Cao, Dan|Xu, Zhong|Fan, Biao|Che, Li|Hu, Junjie|Chen, Bin|Dong, Mingjie|Pilo, Maria G|Cigliano, Antonio|Evert, Katja|Ribback, Silvia|Dombrowski, Frank|Pascale, Rosa M|Cossu, Antonio|Vidili, Gianpaolo|Porcu, Alberto|Simile, Mar | ||||||||||
| PMID: | 28733220 | ||||||||||
| 45. | |||||||||||
| Journal: | EMBO Rep. 2017 Oct;18(10):1837-1853. | ||||||||||
| Title: | LncRNA-PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis. | ||||||||||
| Author: | Wu, Xiang-Song|Wang, Fang|Li, Huai-Feng|Hu, Yun-Ping|Jiang, Lin|Zhang, Fei|Li, Mao-Lan|Wang, Xu-An|Jin, Yun-Peng|Zhang, Yi-Jian|Lu, Wei|Wu, Wen-Guang|Shu, Yi-Jun|Weng, Hao|Cao, Yang|Bao, Run-Fa|Liang, Hai-Bin|Wang, Zheng|Zhang, Yi-Chi|Gong, Wei|Zheng, Lei | ||||||||||
| PMID: | 28887321 | ||||||||||
| 46. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2018 Apr 1;48(4):396-399. | ||||||||||
| Title: | PI3K-mTOR pathway identified as a potential therapeutic target in biliary tract cancer using a newly established patient-derived cell panel assay. | ||||||||||
| Author: | Sakamoto, Yasunari|Yamagishi, Seri|Tanizawa, Yoshinori|Tajimi, Masaomi|Okusaka, Takuji|Ojima, Hidenori | ||||||||||
| PMID: | 29474549 | ||||||||||
| 47. | |||||||||||
| Journal: | Br J Cancer. 2018 Apr;118(7):966-971. | ||||||||||
| Title: | Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study. | ||||||||||
| Author: | Lau, David K|Tay, Rebecca Y|Yeung, Yvonne H|Chionh, Fiona|Mooi, Jennifer|Murone, Carmel|Skrinos, Effie|Price, Timothy J|Mariadason, John M|Tebbutt, Niall C | ||||||||||
| PMID: | 29527009 | ||||||||||
| 48. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Jul 3. pii: 1078-0432.CCR-18-0284. | ||||||||||
| Title: | Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Song, Xinhua|Liu, Xianqiong|Wang, Haichuan|Wang, Jingxiao|Qiao, Yu|Cigliano, Antonio|Utpatel, Kirsten|Ribback, Silvia|Pilo, Maria G|Serra, Marina|Gordan, John D|Che, Li|Zhang, Shanshan|Cossu, Antonio|Porcu, Alberto|Pascale, Rosa Maria|Dombrowski, Frank|Hu | ||||||||||
| PMID: | 30084835 | ||||||||||