Primary Site >> Colorectal Cancer
Gene >> MT1E
| 1. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1990 Jan;17(1):115-20. | ||||||||||
| Title: | [Phase I clinical study of CPT-11. Research group of CPT-11]. | ||||||||||
| Author: | Taguchi, T|Wakui, A|Hasegawa, K|Niitani, H|Furue, H|Ohta, K|Hattori, T | ||||||||||
| PMID: | 2404454 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 1992;22(1):139-45. | ||||||||||
| Title: | Phase I trial of postoperative 5-FU, radiation therapy, and high dose leucovorin for resectable rectal cancer. | ||||||||||
| Author: | Minsky, B D|Cohen, A M|Enker, W E|Kelsen, D P|Kemeny, N|Riechman, B|Saltz, L|Sigurdson, E R|Frankel, J | ||||||||||
| PMID: | 1727111 | ||||||||||
| 3. | |||||||||||
| Journal: | Jpn J Cancer Res. 1995 Aug;86(8):770-5. | ||||||||||
| Title: | In vivo antitumor activity of hexamethylmelamine against human breast, stomach and colon carcinoma xenografts. | ||||||||||
| Author: | Tanino, H|Kubota, T|Yamada, Y|Koh, J|Kase, S|Furukawa, T|Kuo, T H|Saikawa, Y|Kitajima, M|Naito, Y | ||||||||||
| PMID: | 7559101 | ||||||||||
| 4. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1996 Jul;23(8):1011-8. | ||||||||||
| Title: | [LY188011 phase I study. Research Group of Gemcitabine (LY188011)]. | ||||||||||
| Author: | Taguchi, T|Furuse, K|Fukuoka, M|Shimoyama, T|Morimoto, K|Nakamura, T|Furue, H|Majima, H|Niitani, H|Ohta, K|Wakui, A|Nakao, I|Tsukagoshi, S | ||||||||||
| PMID: | 8687215 | ||||||||||
| 5. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1996 Feb;23(3):379-87. | ||||||||||
| Title: | [Nedaplatin]. | ||||||||||
| Author: | Ota, K | ||||||||||
| PMID: | 8712835 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 1999 Oct;5(10 Suppl):3232s-3242s. | ||||||||||
| Title: | Radioimmunotherapy of small volume disease of colorectal cancer metastatic to the liver: preclinical evaluation in comparison to standard chemotherapy and initial results of a phase I clinical study. | ||||||||||
| Author: | Behr, T M|Salib, A L|Liersch, T|Behe, M|Angerstein, C|Blumenthal, R D|Fayyazi, A|Sharkey, R M|Ringe, B|Becker, H|Wormann, B|Hiddemann, W|Goldenberg, D M|Becker, W | ||||||||||
| PMID: | 10541369 | ||||||||||
| 7. | |||||||||||
| Journal: | Curr Opin Investig Drugs. 2000 Sep;1(1):141-9. | ||||||||||
| Title: | ZD-9331 AstraZeneca. | ||||||||||
| Author: | Niculescu-Duvaz, I | ||||||||||
| PMID: | 11249590 | ||||||||||
| 8. | |||||||||||
| Journal: | J Clin Oncol. 2001 May 1;19(9):2433-8. | ||||||||||
| Title: | Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial. | ||||||||||
| Author: | Freyer, G|Bossard, N|Romestaing, P|Mornex, F|Chapet, O|Trillet-Lenoir, V|Gerard, J P | ||||||||||
| PMID: | 11331322 | ||||||||||
| 9. | |||||||||||
| Journal: | Ann Oncol. 2001 May;12(5):701-7. | ||||||||||
| Title: | Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd). | ||||||||||
| Author: | Galanis, E|Goldberg, R|Reid, J|Atherton, P|Sloan, J|Pitot, H|Rubin, J|Adjei, A A|Burch, P|Safgren, S L|Witzig, T E|Ames, M M|Erlichman, C | ||||||||||
| PMID: | 11432631 | ||||||||||
| 10. | |||||||||||
| Journal: | Isr Med Assoc J. 2004 Oct;6(10):595-8. | ||||||||||
| Title: | A phase I study of oral UFT given concomitantly with standard preoperative radiotherapy for rectal cancer. | ||||||||||
| Author: | Pfeffer, M Raphael|Kundel, Yulia|Zehavi, Meir|Catane, Raphael|Koller, Moshe|Zmora, Oded|Elkayam, Ruth|Symon, Zvi | ||||||||||
| PMID: | 15473585 | ||||||||||
| 11. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2008 Oct;35(10):1697-701. | ||||||||||
| Title: | [Phase I study of CPT-11 and continuous 5-FU / l-leucovorin combination therapy(modified AIO regimen)in patients with metastatic colorectal cancer]. | ||||||||||
| Author: | Nakamura, Toshio|Kurachi, Kiyotaka|Fukazawa, Atsuko|Hayashi, Tadataka|Nakamura, Koichi|Nakajima, Akihito|Suzuki, Shohachi|Konno, Hiroyuki | ||||||||||
| PMID: | 18931571 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2010 Jan 15;70(2):609-20. | ||||||||||
| Title: | Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction. | ||||||||||
| Author: | Wilson, Andrew J|Chueh, Anderly C|Togel, Lars|Corner, Georgia A|Ahmed, Naseem|Goel, Sanjay|Byun, Do-Sun|Nasser, Shannon|Houston, Michele A|Jhawer, Minaxi|Smartt, Helena J M|Murray, Lucas B|Nicholas, Courtney|Heerdt, Barbara G|Arango, Diego|Augenlicht, Leo | ||||||||||
| PMID: | 20068171 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2010 Nov;66(6):1113-21. | ||||||||||
| Title: | A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol. | ||||||||||
| Author: | Dickson, Mark A|Shah, Manish A|Rathkopf, Dana|Tse, Archie|Carvajal, Richard D|Wu, Nian|Lefkowitz, Robert A|Gonen, Mithat|Cane, Lauren M|Dials, Heather J|Schwartz, Gary K | ||||||||||
| PMID: | 20953860 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Feb 15;17(4):849-60. | ||||||||||
| Title: | Phase I safety, pharmacokinetic, and pharmacodynamic study of ENMD-2076, a novel angiogenic and Aurora kinase inhibitor, in patients with advanced solid tumors. | ||||||||||
| Author: | Diamond, Jennifer R|Bastos, Bruno R|Hansen, Ryan J|Gustafson, Daniel L|Eckhardt, S Gail|Kwak, Eunice L|Pandya, Shuchi S|Fletcher, Graham C|Pitts, Todd M|Kulikowski, Gillian N|Morrow, Mark|Arnott, Jamie|Bray, Mark R|Sidor, Carolyn|Messersmith, Wells|Shapir | ||||||||||
| PMID: | 21131552 | ||||||||||
| 15. | |||||||||||
| Journal: | Clin Cancer Res. 2015 Feb 15;21(4):701-11. | ||||||||||
| Title: | A phase I study of continuous oral dosing of OSI-906, a dual inhibitor of insulin-like growth factor-1 and insulin receptors, in patients with advanced solid tumors. | ||||||||||
| Author: | Puzanov, Igor|Lindsay, Colin R|Goff, Laura|Sosman, Jeff|Gilbert, Jill|Berlin, Jordan|Poondru, Srinivasu|Simantov, Ronit|Gedrich, Rich|Stephens, Andrew|Chan, Emily|Evans, T R Jeffry | ||||||||||
| PMID: | 25212606 | ||||||||||
| 16. | |||||||||||
| Journal: | Clin Cancer Res. 2015 Mar 1;21(5):1002-9. | ||||||||||
| Title: | Phase I dose-escalation trial of the oral investigational Hedgehog signaling pathway inhibitor TAK-441 in patients with advanced solid tumors. | ||||||||||
| Author: | Goldman, Jonathan|Eckhardt, S Gail|Borad, Mitesh J|Curtis, Kelly K|Hidalgo, Manuel|Calvo, Emiliano|Ryan, David P|Wirth, Lori J|Parikh, Asit|Partyka, James|Faessel, Helene|Gangolli, Esha|Stewart, Sally|Rosen, Lee S|Bowles, Daniel W | ||||||||||
| PMID: | 25501576 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Jun 15;22(12):2897-907. | ||||||||||
| Title: | Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Macaulay, Valentine M|Middleton, Mark R|Eckhardt, S Gail|Rudin, Charles M|Juergens, Rosalyn A|Gedrich, Richard|Gogov, Sven|McCarthy, Sean|Poondru, Srinivasu|Stephens, Andrew W|Gadgeel, Shirish M | ||||||||||
| PMID: | 26831715 | ||||||||||
| 18. | |||||||||||
| Journal: | Radiother Oncol. 2016 Feb;118(2):382-6. | ||||||||||
| Title: | Phase I study of pre-operative continuous 5-FU and sorafenib with external radiation therapy in locally advanced rectal adenocarcinoma. | ||||||||||
| Author: | Kim, Richard|Prithviraj, Gopi Kesaria|Shridhar, Ravi|Hoffe, Sarah E|Jiang, Kun|Zhao, Xiuhua|Chen, Dung-Tsa|Almhanna, Khaldoun|Strosberg, Jonathan|Campos, Tiffany|Shibata, David | ||||||||||
| PMID: | 26861740 | ||||||||||
| 19. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Jul 1;22(13):3209-17. | ||||||||||
| Title: | A Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of Weekly or Every Three Week Ixabepilone and Daily Sunitinib in Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Montero, Alberto J|Kwon, Deukwoo|Flores, Aurea|Kovacs, Krisztina|Trent, Jonathan C|Benedetto, Pasquale|Rocha-Lima, Caio|Merchan, Jaime R | ||||||||||
| PMID: | 26864210 | ||||||||||
| 20. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Jun 1;22(11):2659-67. | ||||||||||
| Title: | Phase I Study of an AKT Inhibitor (MK-2206) Combined with Lapatinib in Adult Solid Tumors Followed by Dose Expansion in Advanced HER2+ Breast Cancer. | ||||||||||
| Author: | Wisinski, Kari B|Tevaarwerk, Amye J|Burkard, Mark E|Rampurwala, Murtuza|Eickhoff, Jens|Bell, Maria C|Kolesar, Jill M|Flynn, Christopher|Liu, Glenn | ||||||||||
| PMID: | 27026198 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2016 Oct 11;7(41):67495-67506. | ||||||||||
| Title: | Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin. | ||||||||||
| Author: | Overman, Michael J|Morris, Van|Moinova, Helen|Manyam, Ganiraju|Ensor, Joe|Lee, Michael S|Eng, Cathy|Kee, Bryan|Fogelman, David|Shroff, Rachna T|LaFramboise, Thomas|Mazard, Thibault|Feng, Tian|Hamilton, Stanley|Broom, Bradley|Lutterbaugh, James|Issa, Jean- | ||||||||||
| PMID: | 27542211 | ||||||||||
| 22. | |||||||||||
| Journal: | Target Oncol. 2017 Dec;12(6):775-785. | ||||||||||
| Title: | A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer. | ||||||||||
| Author: | Wainberg, Zev A|Alsina, Maria|Soares, Heloisa P|Brana, Irene|Britten, Carolyn D|Del Conte, Gianluca|Ezeh, Patrick|Houk, Brett|Kern, Kenneth A|Leong, Stephen|Pathan, Nuzhat|Pierce, Kristen J|Siu, Lillian L|Vermette, Jennifer|Tabernero, Josep | ||||||||||
| PMID: | 29067643 | ||||||||||