Primary Site >> Esophagus Cancer

Gene >> MMP2

Journal: Cancer. 1992 Dec 15;70(12):2747-53.
Title: Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Author: Shima, I|Sasaguri, Y|Kusukawa, J|Yamana, H|Fujita, H|Kakegawa, T|Morimatsu, M
PMID: 1451050
Journal: Gan To Kagaku Ryoho. 1995 Mar;22(4):573-9.
Title: [Postoperative prognostic factors for carcinoma of the thoracic esophagus].
Author: Kakegawa, T|Yamana, H
PMID: 7887653
Journal: Int J Oncol. 1996 Apr;8(4):773-9.
Title: Matrix metalloproteinase 2 and 9 in esophageal cancer.
Author: Kataoka, M|Yamagata, S|Takagi, H|Thant, A|Akiyama, S|Iida, K|Watanabe, T|Saga, S|Kishi, J|Hamaguchi, M
PMID: 21544425
Journal: J Surg Oncol. 2002 Oct;81(2):80-6.
Title: Role of matrix metalloproteinase-9 in in vitro invasion of esophageal carcinoma cells.
Author: Suzuki, Tomotaka|Kuwabara, Yoshiyuki|Iwata, Hiroji|Mitani, Masami|Shinoda, Noriyuki|Sato, Atsushi|Mitsui, Akira|Sugiura, Masahiko|Kato, Joji|Fujii, Yoshitaka
PMID: 12355408
Journal: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Mar;35(3):247-54.
Title: [Functions of neutrophil gelatinase-associated lipocalin in the esophageal carcinoma cell line SHEEC].
Author: Li, En-Min|Xu, Li-Yan|Cai, Wei-Jia|Xiong, Hua-Qi|Shen, Zhong-Ying|Zeng, Yi
PMID: 12621549
Journal: Gastric Cancer. 2003;6(1):30-8.
Title: Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Author: Elnemr, Ayman|Yonemura, Yutaka|Bandou, Etsurou|Kinoshita, Kazuo|Kawamura, Taiichi|Takahashi, Shigeru|Tochiori, Shizuka|Endou, Yoshio|Sasaki, Takuma
PMID: 12673424
Journal: Cancer. 2003 May 15;97(10):2412-9.
Title: Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression.
Author: Yamashita, Keishi|Upadhay, Sunil|Mimori, Kohshi|Inoue, Hiroshi|Mori, Masaki
PMID: 12733139
Journal: J Cancer Res Clin Oncol. 2004 Jan;130(1):37-44.
Title: Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Author: Samantaray, S|Sharma, R|Chattopadhyaya, T K|Gupta, S Datta|Ralhan, R
PMID: 14569466
Journal: Zhonghua Zhong Liu Za Zhi. 2005 Feb;27(2):96-8.
Title: [Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma].
Author: Li, Jie-ru|Qi, Feng-ying|Li, Li
PMID: 15946548
Journal: Biochem Biophys Res Commun. 2005 Nov 11;337(1):355-62.
Title: Role of fascin in the proliferation and invasiveness of esophageal carcinoma cells.
Author: Xie, J J|Xu, L Y|Zhang, H H|Cai, W J|Mai, R Q|Xie, Y M|Yang, Z M|Niu, Y D|Shen, Z Y|Li, E M
PMID: 16185662
Journal: Am J Hum Genet. 2005 Jul;77(1):27-40. Epub 2005 May 9.
Title: An entropy-based statistic for genomewide association studies.
Author: Zhao, Jinying|Boerwinkle, Eric|Xiong, Momiao
PMID: 15931594
Journal: Cancer Invest. 2009 May;27(4):443-52.
Title: Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity.
Author: Augoff, K|Grabowski, K|Rabczynski, J|Kolondra, A|Tabola, R|Sikorski, A F
PMID: 19212830
Journal: Ann Surg Oncol. 2009 May;16(5):1384-9.
Title: Neoadjuvant radiochemotherapy increases matrix metalloproteinase activity in healthy tissue in esophageal cancer patients.
Author: Rieff, E A|Hendriks, T|Rutten, H J T|Nieuwenhuijzen, G A P|Gosens, M J E M|van den Brule, A J C|Nienhuijs, S W|de Hingh, I H J T
PMID: 19224281
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Jul;43(7):559-64.
Title: [Genetic polymorphisms in STK15 and MMP-2 associated susceptibility to esophageal cancer in Mongolian population].
Author: Chen, Xia-Bin|Chen, Guang-Lie|Liu, Jun-Niao|Yang, Jing-Zhong|Yu, Dian-Ke|Lin, Dong-Xin|Tan, Wen
PMID: 19954064
Journal: Chin J Cancer. 2010 Jul;29(7):689-96.
Title: Expression of Bmi-1 gene in esophageal carcinoma cell EC9706 and its effect on cell cycle, apoptosis and migration.
Author: Wang, Ju-Feng|Liu, Ying|Liu, Wen-Jing|He, Su-Ying
PMID: 20591222
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jul;30(7):1541-4.
Title: [Expression of S100A4 in esophageal squamous cell carcinoma and its relation to tumor invasion and metastasis].
Author: Zhang, Hong-yan|Zheng, Xian-zhao|Xuan, Xiao-yan|Wang, Xin-hua|Wang, Feng|Li, Shan-shan
PMID: 20650761
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Sep;41(5):755-9.
Title: [Inhibitory effect and molecular mechanism of silencing S100A4 gene on the growth of transplanted tumor of human esophageal carcinoma EC-1 cells in nude mice].
Author: Zhang, Hong-yan|Zheng, Xian-zhao|Xuan, Xiao-yan|Wang, Xin-hua|Wang, Feng|Li, Shan-shan
PMID: 21302434
Journal: J Cell Physiol. 2011 Jul;226(7):1860-7.
Title: Human mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vivo.
Author: Tian, Lin Li Hui|Yue, Weiming|Zhu, Feng|Li, Shuhai|Li, Wenjun
PMID: 21442622
Journal: Cancer Biol Ther. 2011 Jun 1;11(11):981-7. Epub 2011 Jun 1.
Title: Inhibition of hypoxia inducible factor 1alpha expression suppresses the progression of esophageal squamous cell carcinoma.
Author: Zhu, Hong|Feng, Yadong|Zhang, Jie|Zhou, Xiqiao|Hao, Bo|Zhang, Guoxin|Shi, Ruihua
PMID: 21519196
Journal: Ann Surg Oncol. 2011 Feb;18(2):535-42.
Title: FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma.
Author: Nishida, Naohiro|Mimori, Koshi|Yokobori, Takehiko|Sudo, Tomoya|Tanaka, Fumiaki|Shibata, Kohei|Ishii, Hideshi|Doki, Yuichiro|Mori, Masaki
PMID: 20803080
Journal: Dig Dis Sci. 2012 Jan;57(1):32-7.
Title: Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150.
Author: Shen, Yu-Guang|Xu, Yi-Jun|Shi, Zhen-Liang|Han, Hong-Li|Sun, Da-Qiang|Zhang, Xun
PMID: 21879284
Journal: Folia Histochem Cytobiol. 2012 Apr 24;50(1):12-9.
Title: The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer.
Author: Groblewska, Magdalena|Siewko, Maria|Mroczko, Barbara|Szmitkowski, Maciej
PMID: 22532131
Journal: Carcinogenesis. 2012 Nov;33(11):2147-54.
Title: MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis.
Author: Wang, Kai|Li, Juan|Guo, Hong|Xu, Xueqing|Xiong, Gang|Guan, Xingying|Liu, Botao|Li, Junxia|Chen, Xuedan|Yang, Kang|Bai, Yun
PMID: 22859270
Journal: Zhonghua Yi Xue Za Zhi. 2012 Jun 19;92(23):1621-5.
Title: [Small interfering RNA in silencing cox-2 expression enhances radiosensitivity of esophageal cancer EC9706 cell].
Author: Wu, Hui|Lu, Xiao-xu|Liu, Dong-mei|Zhao, Guo-qiang|Fan, Qing-xia
PMID: 22944132
Journal: Cancer Gene Ther. 2012 Dec;19(12):875-9.
Title: Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector.
Author: Song, H|Song, C|Wang, H|Li, C|Yang, F|Lu, S-H|Lin, C|Zhan, Q|Wang, X|Qian, H
PMID: 23079671
Journal: Acta Med Okayama. 2012;66(5):399-407.
Title: HIF-1alpha contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
Author: Jing, Shao-Wu|Wang, Ya-Di|Kuroda, Masahiro|Su, Jing-Wei|Sun, Guo-Gui|Liu, Qing|Cheng, Yun-Jie|Yang, Cong-Rong
PMID: 23093058
Journal: Folia Histochem Cytobiol. 2012;50(4):590-8.
Title: Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Author: Groblewska, Magdalena|Mroczko, Barbara|Kozlowski, Miroslaw|Niklinski, Jacek|Laudanski, Jerzy|Szmitkowski, Maciej
PMID: 23264224
Journal: J Cancer Res Clin Oncol. 2013 Sep;139(9):1433-47.
Title: Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis.
Author: Li, Xiaoying|Qu, Lianxi|Zhong, Yu|Zhao, Yingjie|Chen, Hongyan|Daru, Lu
PMID: 23644699
Journal: Int J Clin Exp Med. 2013 Sep 1;6(8):700-5. eCollection 2013.
Title: MMP-2 and DcR3 expression in esophageal cancer tissue and correlation with patient survival.
Author: Ao, Ran|Du, Ya-Qi|Wang, Ying|Chen, Yu-Shuai|Wang, Bing-Yuan
PMID: 24040480
Journal: Dis Esophagus. 2013 Jan;26(1):75-83.
Title: Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Author: Jing, S-w|Wang, Y-d|Chen, L-Q|Sang, M-x|Zheng, M-m|Sun, G-g|Liu, Q|Cheng, Y-j|Yang, C-r
PMID: 22340517
Journal: Tumour Biol. 2014 Feb;35(2):995-1002.
Title: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma.
Author: Liu, Kai|Luo, Yue|Tian, Hui|Yu, Kai-Zhong|He, Jin-Xian|Shen, Wei-Yu
PMID: 24022664
Journal: World J Gastroenterol. 2014 Dec 21;20(47):17894-904.
Title: HIF-1alpha induces VE-cadherin expression and modulates vasculogenic mimicry in esophageal carcinoma cells.
Author: Tang, Na-Na|Zhu, Hong|Zhang, Hong-Jie|Zhang, Wei-Feng|Jin, Hai-Lin|Wang, Lu|Wang, Pin|He, Gui-Jun|Hao, Bo|Shi, Rui-Hua
PMID: 25548487
Journal: Int J Clin Exp Med. 2014 Sep 15;7(9):2530-40. eCollection 2014.
Title: High GPX1 expression promotes esophageal squamous cell carcinoma invasion, migration, proliferation and cisplatin-resistance but can be reduced by vitamin D.
Author: Gan, Xiangfeng|Chen, Baishen|Shen, Zhuojian|Liu, Yeqing|Li, Haifeng|Xie, Xuan|Xu, Xia|Li, Haigang|Huang, Zhiquan|Chen, Ju
PMID: 25356106
Journal: Cancer Cell Int. 2014 Sep 24;14(1):93.
Title: Human umbilical cord mesenchymal stem cells promote carcinoma growth and lymph node metastasis when co-injected with esophageal carcinoma cells in nude mice.
Author: Yang, Xiaoya|Li, Zhu|Ma, Yintu|Gao, Jun|Liu, Surui|Gao, Yuhua|Wang, Gengyin
PMID: 25298750
Journal: Clin Cancer Res. 2014 Dec 1;20(23):6153-62.
Title: Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.
Author: Shi, Feng|Shang, Li|Pan, Bei-Qing|Wang, Xiao-Min|Jiang, Yan-Yi|Hao, Jia-Jie|Zhang, Yu|Cai, Yan|Xu, Xin|Zhan, Qi-Min|Wang, Ming-Rong
PMID: 25231404
Journal: Biomed Pharmacother. 2014 Jul;68(6):745-50.
Title: Low-dose decitabine induces MAGE-A expression and inhibits invasion via suppression of NF-kappaB2 and MMP2 in Eca109 cells.
Author: Liu, Wei-hua|Sang, Mei-xiang|Hou, Shu-yun|Zhang, Chao|Shan, Bao-en
PMID: 25123082
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2014 Jun;34(6):798-801.
Title: [Amphotericin B suppresses migration and invasion of esophageal carcinoma Eca109 cells in hypoxic microenvironment by down-regulating hypoxia-inducible factor-1alpha activity].
Author: Kang, Qiangqiang|Tang, Min|Hou, Yanli|Duan, Liqun|Chen, Xingyue|Shu, Jin|Wu, Furong|Wang, Ying|Li, Shaolin
PMID: 24968833
Journal: Oncol Rep. 2014 May;31(5):2298-304.
Title: Functional expression of TLR9 in esophageal cancer.
Author: Zhang, Yanli|Wang, Qiuyan|Ma, Ailing|Li, Yunhong|Li, Rui|Wang, Yin
PMID: 24647486
Journal: J Transl Med. 2014 Jan 4;12:1.
Title: XB130 promotes proliferation and invasion of gastric cancer cells.
Author: Shi, Min|Zheng, Dayong|Sun, Li|Wang, Lin|Lin, Li|Wu, Yajun|Zhou, Minyu|Liao, Wenjun|Liao, Yulin|Zuo, Qiang|Liao, Wangjun
PMID: 24387290
Journal: Mod Pathol. 2014 May;27(5):775-83.
Title: ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Author: Yang, Lang|Ren, Yong|Yu, Xi|Qian, Feng|Bian, Bai-Shi-Jiao|Xiao, Hua-liang|Wang, Wei-guang|Xu, Sen-lin|Yang, Jing|Cui, Wei|Liu, Qiang|Wang, Zhe|Guo, Wei|Xiong, Gang|Yang, Kang|Qian, Cheng|Zhang, Xia|Zhang, Peng|Cui, You-hong|Bian, Xiu-wu
PMID: 24201124
Journal: Cancer Sci. 2014 Jan;105(1):134-40.
Title: NRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.
Author: Uraoka, Naohiro|Oue, Naohide|Sakamoto, Naoya|Sentani, Kazuhiro|Oo, Htoo Zarni|Naito, Yutaka|Noguchi, Tsuyoshi|Yasui, Wataru
PMID: 24168165
Journal: Dis Esophagus. 2014 Sep-Oct;27(7):685-92.
Title: Blockage of Nrf2 suppresses the migration and invasion of esophageal squamous cell carcinoma cells in hypoxic microenvironment.
Author: Shen, H|Yang, Y|Xia, S|Rao, B|Zhang, J|Wang, J
PMID: 24028437
Journal: Mol Carcinog. 2014 May;53(5):360-79.
Title: Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1alpha-induced invasion of human esophageal carcinoma cells.
Author: Lin, Meng-Liang|Lu, Yao-Cheng|Chen, Hung-Yi|Lee, Chuan-Chun|Chung, Jing-Gung|Chen, Shih-Shun
PMID: 23192861
Journal: Oncol Rep. 2014 Jun;31(6):2820-6.
Title: Upregulated expression and activation of membraneassociated proteases in esophageal squamous cell carcinoma.
Author: Augoff, Katarzyna|Hryniewicz-Jankowska, Anita|Tabola, Renata|Czapla, Leszek|Szelachowski, Piotr|Wierzbicki, Jaroslaw|Grabowski, Krzysztof|Sikorski, Aleksander F
PMID: 24789592
Journal: Int J Oncol. 2015 Dec;47(6):2255-63.
Title: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells.
Author: Hadisaputri, Yuni Elsa|Miyazaki, Tatsuya|Suzuki, Shigemasa|Kubo, Norio|Zuhrotun, Ade|Yokobori, Takehiko|Abdulah, Rizky|Yazawa, Shin|Kuwano, Hiroyuki
PMID: 26498695
Journal: Med Oncol. 2015 Aug;32(8):222.
Title: Influence of lymphatic endothelial cells on proliferation and invasiveness of esophageal carcinoma cells in vitro and lymphangiogenesis in vivo.
Author: Yang, Xu|Zhai, Nana|Sun, Miaomiao|Zhao, Zhihua|Yang, Jianping|Chen, Kuisheng|Zhang, Hongxin
PMID: 26202395
Journal: Genet Mol Res. 2015 May 4;14(2):4616-24.
Title: Matrix metalloproteinase variants associated with risk and clinical outcome of esophageal cancer.
Author: Zhang, L|Xi, R-X|Zhang, X-Z
PMID: 25966235
Journal: Histol Histopathol. 2015 Oct;30(10):1193-202.
Title: Molecular markers predicting lymph node metastasis in early esophageal cancer.
Author: Plum, Patrick S|Warnecke-Eberz, Ute|Dhaouadi, Oulfa|Alakus, Hakan|Drebber, Uta|Metzger, Ralf|Prenzel, Klaus L|Holscher, Arnulf H|Bollschweiler, Elfriede
PMID: 25869644
Journal: Neoplasma. 2015;62(3):384-90.
Title: miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
Author: Qi, Y|Li, X|Zhao, S
PMID: 25866219
Journal: Tumour Biol. 2015 Aug;36(8):5859-64.
Title: Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloproteinase 2.
Author: Zhang, Yi|Pan, Tiecheng|Zhong, Xiaoxuan|Cheng, Cai
PMID: 25724186
Journal: Mol Med Rep. 2016 Feb;13(2):1097-104.
Title: Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/beta-catenin signaling.
Author: Tantai, Ji-Cheng|Zhang, Yao|Zhao, Heng
PMID: 26647768
Journal: Exp Ther Med. 2016 Sep;12(3):1525-1530.
Title: Inhibitory effect of alpha-solanine on esophageal carcinoma in vitro.
Author: Wang, Lei|Sun, Qian-Qian|Zhang, Shi-Jie|Du, Yu-Wen|Wang, Yuan-Yuan|Zang, Wen-Qiao|Chen, Xiao-Nan|Zhao, Guo-Qiang
PMID: 27588073
Journal: Oncotarget. 2016 Oct 11;7(41):67612-67625.
Title: Gene-gene interactions in gastrointestinal cancer susceptibility.
Author: Kim, Jineun|Yum, Seoyun|Kang, Changwon|Kang, Suk-Jo
PMID: 27588484
Journal: Pak J Pharm Sci. 2016 Jul;29(4 Suppl):1339-42.
Title: The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Author: Guo, Xiao-Qi|Li, Xing-Ya
PMID: 27592483
Journal: Oncol Res. 2017 Apr 14;25(4):485-493.
Title: High TRAF6 Expression Is Associated With Esophageal Carcinoma Recurrence and Prompts Cancer Cell Invasion.
Author: Liu, Xinyang|Wang, Zhichao|Zhang, Guoliang|Zhu, Qikun|Zeng, Hui|Wang, Tao|Gao, Feng|Qi, Zhan|Zhang, Jinwen|Wang, Rui
PMID: 27697099
Journal: Cancer Res Treat. 2017 Feb 24.
Title: Downregulation of HuR Inhibits the Progression of Esophageal Cancer Through Interleukin-18.
Author: Xu, Xiaohui|Song, Cheng|Chen, Zhihua|Yu, Chenxiao|Wang, Yi|Tang, Yiting|Luo, Judong
PMID: 28231690
Journal: Sci Rep. 2017 Apr 12;7(1):854.
Title: The adjuvant value of Andrographis paniculata in metastatic esophageal cancer treatment - from preclinical perspectives.
Author: Li, Lin|Yue, Grace Gar-Lee|Lee, Julia Kin-Ming|Wong, Eric Chun-Wai|Fung, Kwok-Pui|Yu, Jun|Lau, Clara Bik-San|Chiu, Philip Wai-Yan
PMID: 28405006
Journal: Oncol Lett. 2017 Aug;14(2):1387-1394.
Title: Analysis of salivary microRNA expression profiles and identification of novel biomarkers in esophageal cancer.
Author: Du, Jiang|Zhang, Lin
PMID: 28789354
Journal: Int J Mol Sci. 2017 Aug 23;18(9). pii: E1833.
Title: miR-145-5p Suppresses Tumor Cell Migration, Invasion and Epithelial to Mesenchymal Transition by Regulating the Sp1/NF-kappaB Signaling Pathway in Esophageal Squamous Cell Carcinoma.
Author: Mei, Li-Li|Wang, Wen-Jun|Qiu, Yun-Tan|Xie, Xiu-Feng|Bai, Jie|Shi, Zhi-Zhou
PMID: 28832500
Journal: Oncol Lett. 2018 Jan;15(1):1229-1235.
Title: Overexpression of asparaginyl endopeptidase is significant for esophageal carcinoma metastasis and predicts poor patient prognosis.
Author: Liu, Xinyang|Wang, Zhichao|Zhang, Guoliang|Zhu, Qikun|Zeng, Hui|Wang, Tao|Gao, Feng|Qi, Zhan|Zhang, Jinwen|Wang, Rui
PMID: 29399177
Journal: Oncol Lett. 2018 Apr;15(4):4907-4911.
Title: Effect of galectin-3 on vasculogenic mimicry in esophageal cancer cells.
Author: Zhang, Jingxin|Deng, Guodong|Qiao, Lili|Luo, Hui|Liu, Qiqi|Liang, Ning|Xie, Jian|Zhang, Jiandong
PMID: 29552129
Journal: Mol Med Rep. 2018 Oct;18(4):3631-3640.
Title: MicroRNA6753p promotes esophageal squamous cell cancer cell migration and invasion.
Author: Xiao, Qi|Chen, Tianming|Wu, Yao|Wu, Wenxiu|Xu, Yandi|Gong, Zhunan|Chen, Shilin
PMID: 30106155