Primary Site >> Esophagus Cancer

Gene >> MDM2

Journal: Mol Carcinog. 1993;8(4):306-11.
Title: Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas.
Author: Esteve, A|Lehman, T|Jiang, W|Weinstein, I B|Harris, C C|Ruol, A|Peracchia, A|Montesano, R|Hollstein, M
PMID: 8280379
Journal: Gan To Kagaku Ryoho. 1996 Jul;23(8):972-81.
Title: [Prognostic factors for esophageal cancer--from the viewpoint of molecular biology].
Author: Shimada, Y|Imamura, M
PMID: 8687232
Journal: Cancer Genet Cytogenet. 1996 Jul 15;89(2):184-5.
Title: No evidence for the amplifications of MDM2 and C-myc genes involved in the genetic susceptibility to esophageal cancer in a high-risk area of north China.
Author: Zhu, D|Wang, L|Zhang, C|Wang, X|Mao, X|Jia, Y|Yan, S|Wu, M
PMID: 8697432
Journal: Ann Surg. 1997 Aug;226(2):162-8.
Title: Genetic alterations in patients with esophageal cancer with short- and long-term survival rates after curative esophagectomy.
Author: Shimada, Y|Imamura, M|Shibagaki, I|Tanaka, H|Miyahara, T|Kato, M|Ishizaki, K
PMID: 9296509
Journal: Adv Exp Med Biol. 1997;407:41-53.
Title: Involvement of the multiple tumor suppressor genes and 12-lipoxygenase in human prostate cancer. Therapeutic implications.
Author: Gao, X|Porter, A T|Honn, K V
PMID: 9321930
Journal: Nucleic Acids Res. 1998 Aug 1;26(15):3453-9.
Title: The MDM2 gene amplification database.
Author: Momand, J|Jung, D|Wilczynski, S|Niland, J
PMID: 9671804
Journal: Gan To Kagaku Ryoho. 1998 Nov;25(13):2011-20.
Title: [Prognostic factors of esophageal cancer].
Author: Kitagawa, Y|Ueda, M|Ando, N|Ozawa, S|Takeuchi, H|Kitajima, M
PMID: 9838901
Journal: Clin Cancer Res. 2000 Jul;6(7):2851-9.
Title: Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: involvement of p53 accumulation via ARF-mediated MDM2 down-regulation.
Author: Itoshima, T|Fujiwara, T|Waku, T|Shao, J|Kataoka, M|Yarbrough, W G|Liu, T J|Roth, J A|Tanaka, N|Kodama, M
PMID: 10914734
Journal: Pathol Oncol Res. 2001;7(3):203-8.
Title: Alterations in MDM2 expression in esophageal squamous cell carcinoma: relationship with p53 status.
Author: Arora, S|Mathew, R|Mathur, M|Chattopadhayay, T K|Ralhan, R
PMID: 11692147
Journal: Oncogene. 2002 Feb 14;21(8):1208-16.
Title: Facilitation of adenoviral wild-type p53-induced apoptotic cell death by overexpression of p33(ING1) in T.Tn human esophageal carcinoma cells.
Author: Shimada, Hideaki|Liu, Tian-Ling|Ochiai, Takenori|Shimizu, Takanori|Haupt, Ygal|Hamada, Hirofumi|Abe, Toshihiro|Oka, Masaaki|Takiguchi, Masaki|Hiwasa, Takaki
PMID: 11850840
Journal: Mol Carcinog. 2002 Mar;33(3):181-8.
Title: Restoration of wild-type conformation and activity of a temperature-sensitive mutant of p53 (p53(V272M)) by the cytoprotective aminothiol WR1065 in the esophageal cancer cell line TE-1.
Author: North, Sophie|Pluquet, Olivier|Maurici, Daniela|El-Ghissassi, Fatiha|Hainaut, Pierre
PMID: 11870884
Journal: Hum Gene Ther. 2002 Jul 20;13(11):1373-82.
Title: Adenovirus-mediated p14ARF gene transfer cooperates with Ad5CMV-p53 to induce apoptosis in human cancer cells.
Author: Tango, Yasuhisa|Fujiwara, Toshiyoshi|Itoshima, Takahiro|Takata, Yoshiko|Katsuda, Kou|Uno, Futoshi|Ohtani, Shoichiro|Tani, Tohru|Roth, Jack A|Tanaka, Noriaki
PMID: 12162819
Journal: Int J Oncol. 2002 Sep;21(3):547-52.
Title: Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T.Tn expressing non-functional mutated p53.
Author: Sakai, Taro|Furihata, Tadashi|Kawamata, Hitoshi|Omotehara, Fumie|Shinagawa, Yasuhiro|Imura, Johji|Kubota, Keiichi|Terano, Akira|Fujimori, Takahiro
PMID: 12168098
Journal: Exp Mol Pathol. 2002 Dec;73(3):198-208.
Title: MDM2 and CDK4 expression in carcinosarcoma of the esophagus: comparison with squamous cell carcinoma and review of the literature.
Author: Nikitakis, Nikolaos G|Drachenberg, Cinthia B|Papadimitriou, John C
PMID: 12565795
Journal: Clin Cancer Res. 2003 Jan;9(1):243-9.
Title: Cell culture in esophageal squamous cell carcinoma and the association with molecular markers.
Author: Shimada, Yutaka|Maeda, Masato|Watanabe, Go|Yamasaki, Seiji|Komoto, Izumi|Kaganoi, Junichi|Kan, Takatsugu|Hashimoto, Yosuke|Imoto, Issei|Inazawa, Johji|Imamura, Masayuki
PMID: 12538476
Journal: Pathol Int. 2005 Feb;55(2):53-62.
Title: Human papillomavirus infection in Egyptian esophageal carcinoma: correlation with p53, p21, mdm2, C-erbB2 and impact on survival.
Author: Bahnassy, Abeer A|Zekri, Abdel-Rahman N|Abdallah, Samira|El-Shehaby, Amal M R|Sherif, Ghada M
PMID: 15693850
Journal: Exp Oncol. 2006 Sep;28(3):235-40.
Title: Relationship between HPV16/18 E6 and 53, 21WAF1, MDM2, Ki67 and cyclin D1 expression in esophageal squamous cell carcinoma: comparative study by using tissue microarray technology.
Author: Qi, Z L|Huo, X|Xu, X J|Zhang, B|Du, M G|Yang, H W|Zheng, L K|Li, J|Shen, Z Y
PMID: 17080019
Journal: Int J Cancer. 2006 Aug 1;119(3):508-14.
Title: Id-1 promotes proliferation of p53-deficient esophageal cancer cells.
Author: Hui, Cheuk Man|Cheung, Pak Yan|Ling, Ming Tat|Tsao, Sai Wah|Wang, Xianghong|Wong, Yong Chuan|Cheung, Annie L M
PMID: 16506209
Journal: Cancer Sci. 2006 Jun;97(6):554-61.
Title: Phase I/II adenoviral p53 gene therapy for chemoradiation resistant advanced esophageal squamous cell carcinoma.
Author: Shimada, Hideaki|Matsubara, Hisahiro|Shiratori, Tooru|Shimizu, Takanori|Miyazaki, Shinichi|Okazumi, Shinichi|Nabeya, Yoshihiro|Shuto, Kiyohiko|Hayashi, Hideki|Tanizawa, Tooru|Nakatani, Yukio|Nakasa, Hiromitsu|Kitada, Mitsukazu|Ochiai, Takenori
PMID: 16734736
Journal: Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6. Epub 2007 Apr 30.
Title: PACT is a negative regulator of p53 and essential for cell growth and embryonic development.
Author: Li, Li|Deng, Binwei|Xing, Guichun|Teng, Yan|Tian, Chunyan|Cheng, Xuan|Yin, Xiushan|Yang, Juntao|Gao, Xue|Zhu, Yunping|Sun, Qihong|Zhang, Lingqiang|Yang, Xiao|He, Fuchu
PMID: 17470788
Journal: Exp Mol Pathol. 2009 Aug;87(1):42-7.
Title: Expression of Akt and Mdm2 in human esophageal squamous cell carcinoma.
Author: Takahashi, Ken|Miyashita, Masao|Makino, Hiroshi|Akagi, Ichiro|Orita, Hajime|Hagiwara, Nobutoshi|Nomura, Tsutomu|Gabrielson, Edward W|Tajiri, Takashi
PMID: 19124015
Journal: Clin Cancer Res. 2009 May 1;15(9):3103-9.
Title: p53 Arg72Pro and MDM2 T309G polymorphisms, histology, and esophageal cancer prognosis.
Author: Cescon, David W|Bradbury, Penelope A|Asomaning, Kofi|Hopkins, Jessica|Zhai, Rihong|Zhou, Wei|Wang, Zhaoxi|Kulke, Matthew|Su, Li|Ma, Clement|Xu, Wei|Marshall, Ariela L|Heist, Rebecca Suk|Wain, John C|Lynch, Thomas J Jr|Christiani, David C|Liu, Geoffrey
PMID: 19383811
Journal: BMC Cancer. 2010 Apr 13;10:138.
Title: p16INK4a hypermethylation and p53, p16 and MDM2 protein expression in esophageal squamous cell carcinoma.
Author: Taghavi, Noushin|Biramijamal, Firouzeh|Sotoudeh, Masoud|Khademi, Hooman|Malekzadeh, Reza|Moaven, Omeed|Memar, Bahram|A'rabi, Azadeh|Abbaszadegan, Mohammad Reza
PMID: 20388212
Journal: J Gastrointest Surg. 2011 Jan;15(1):48-56.
Title: Functional polymorphisms associated with disease-free survival in resected carcinoma of the esophagus.
Author: Boonstra, Jurjen J|van Marion, Ronald|Tilanus, Hugo W|Dinjens, Winand N M
PMID: 20922573
Journal: Ann Surg Oncol. 2011 May;18(5):1469-77.
Title: MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus.
Author: Hsu, Han-Shui|Chen, Hsin-Wu|Kao, Chia-Li|Wu, Min-Li|Li, Anna Fen-Yau|Cheng, Tzu-Hao
PMID: 21080085
Journal: PLoS One. 2015 Jun 23;10(6):e0130284.
Title: The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells.
Author: Wang, Cong|Jiang, Liping|Wang, Saiqi|Shi, Hongge|Wang, Junwei|Wang, Ran|Li, Yongmei|Dou, Yinhui|Liu, Ying|Hou, Guiqin|Ke, Yu|Liu, Hongmin
PMID: 26103161
Journal: Int J Clin Exp Med. 2015 Aug 15;8(8):13413-6. eCollection 2015.
Title: MDM2 T309G polymorphism and esophageal cancer risk: a meta-analysis.
Author: Lei, Caipeng|Zhang, Weiguo|Fan, Junli|Qiao, Bin|Chen, Qiang|Liu, Qin|Zhao, Chunling
PMID: 26550276
Journal: Ann Oncol. 2015 Apr;26(4):624-44.
Title: A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.
Author: Findlay, J M|Middleton, M R|Tomlinson, I
PMID: 25214541
Journal: Dis Esophagus. 2015 Aug-Sep;28(6):593-601.
Title: Current evidence on the relationship between murine double minute 2 T309G polymorphism and esophageal cancer susceptibility.
Author: Chen, B|Xiong, M-M|Meng, X-L
PMID: 24844868
Journal: Dis Esophagus. 2016 Oct;29(7):856-863.
Title: Association between positive murine double minute 2 expression and clinicopathological characteristics of esophageal squamous cell carcinoma: a meta-analysis.
Author: Chen, J Y|Yang, H|Wen, J|Luo, K J|Liu, Q W|Lei, J Y|Zhen, Y Z|Fu, J H
PMID: 25873358
Journal: Pharmacogenomics J. 2016 Jun;16(3):266-71.
Title: Genetic risk of subsequent esophageal cancer in lymphoma and breast cancer long-term survival patients: a pilot study.
Author: Boldrin, E|Rumiato, E|Fassan, M|Rugge, M|Cagol, M|Marino, D|Chiarion-Sileni, V|Ruol, A|Gusella, M|Pasini, F|Amadori, A|Saggioro, D
PMID: 26054330
Journal: Oncol Rep. 2016 Apr;35(4):2223-7.
Title: MDM2 gene amplification in esophageal carcinoma.
Author: Michalk, Maike|Meinrath, Jeannine|Kunstlinger, Helen|Koitzsch, Ulrike|Drebber, Uta|Merkelbach-Bruse, Sabine|Bollschweiler, Elfriede|Kloth, Michael|Hartmann, Wolfgang|Holscher, Arnulf|Quaas, Alexander|Grimminger, Peter P|Odenthal, Margarete
PMID: 26796597
Journal: Tumour Biol. 2016 Oct 24.
Title: The long non-coding RNA maternally expressed gene 3 activates p53 and is downregulated in esophageal squamous cell cancer.
Author: Lv, Desheng|Sun, Run|Yu, Qian|Zhang, Xuefei
PMID: 27778235
Journal: Mol Cell Biochem. 2017 Jul;431(1-2):75-85.
Title: Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors.
Author: Ohnami, Shumpei|Ohshima, Keiichi|Nagashima, Takeshi|Urakami, Kenichi|Shimoda, Yuji|Saito, Junko|Naruoka, Akane|Hatakeyama, Keiichi|Mochizuki, Tohru|Serizawa, Masakuni|Ohnami, Sumiko|Kusuhara, Masatoshi|Yamaguchi, Ken
PMID: 28258440
Journal: Pathol Oncol Res. 2017 Mar 24.
Title: Nutlin-3, an Antagonist of MDM2, Enhances the Radiosensitivity of Esophageal Squamous Cancer with Wild-Type p53.
Author: He, Tianli|Guo, Jiayou|Song, Hongmei|Zhu, Hongcheng|Di, Xiaoke|Min, Hua|Wang, Yuandong|Chen, Guangzong|Dai, Wangshu|Ma, Jianhua|Sun, Xinchen|Ma, Jianxin
PMID: 28341911
Journal: Oncol Lett. 2017 Dec;14(6):6915-6922.
Title: Combination of histoculture drug response assay and qPCR as an effective method to screen biomarkers for personalized chemotherapy in esophageal cancer.
Author: Wei, Bin|Wang, Jiru|Zhang, Xiaohui|Qian, Zhaoye|Wu, Jingjing|Sun, Yuan|Han, Qin|Wan, Li|Zhu, Jing|Gao, Yong|Chen, Xiaofei
PMID: 29163710
Journal: Biomed Pharmacother. 2018 Nov;107:139-145.
Title: Survivin is critically involved in VEGFR2 signaling-mediated esophageal cancer cell survival.
Author: Meng, Lingxin|Fuhao, Zhu|Xiaoming, Zhou|Yuxiu, Zheng|Zhaojun, Ding|Bingcheng, Li|Meiling, Xu|Shuyan, Sun
PMID: 30086460