Primary Site >> Biliary tract Cancer
Gene >> MAP2K1
| 1. | |||||||||||
| Journal: | Int J Oncol. 2006 Apr;28(4):915-21. | ||||||||||
| Title: | The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines. | ||||||||||
| Author: | Miyata, Hideki|Sasaki, Tamito|Kuwahara, Kenichi|Serikawa, Masahiro|Chayama, Kazuaki | ||||||||||
| PMID: | 16525641 | ||||||||||
| 2. | |||||||||||
| Journal: | Virchows Arch. 2006 Jun;448(6):776-87. | ||||||||||
| Title: | Cystic cholangiomas after transplantation of pancreatic islets into the livers of diabetic rats. | ||||||||||
| Author: | Evert, Matthias|Schildhaus, Hans-Ulrich|Schneider-Stock, Regine|Dombrowski, Frank | ||||||||||
| PMID: | 16601979 | ||||||||||
| 3. | |||||||||||
| Journal: | J Surg Res. 2006 Nov;136(1):78-84. Epub 2006 Sep 1. | ||||||||||
| Title: | Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-Met. | ||||||||||
| Author: | Leelawat, Kawin|Leelawat, Surang|Tepaksorn, Panada|Rattanasinganchan, Panthip|Leungchaweng, Anicha|Tohtong, Rutaiwan|Sobhon, Prasert | ||||||||||
| PMID: | 16950403 | ||||||||||
| 4. | |||||||||||
| Journal: | World J Gastroenterol. 2007 Mar 14;13(10):1561-8. | ||||||||||
| Title: | Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion. | ||||||||||
| Author: | Leelawat, Kawin|Leelawat, Surang|Narong, Siriluck|Hongeng, Suradej | ||||||||||
| PMID: | 17461449 | ||||||||||
| 5. | |||||||||||
| Journal: | Expert Rev Gastroenterol Hepatol. 2011 Oct;5(5):579-81. | ||||||||||
| Title: | Inhibitor of MEK1/2, selumetinib, for biliary tract cancer. | ||||||||||
| Author: | Furuse, Junji|Nagashima, Fumio | ||||||||||
| PMID: | 21910575 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann Surg Oncol. 2014 Nov;21(12):3827-34. | ||||||||||
| Title: | Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets. | ||||||||||
| Author: | Zhu, Andrew X|Borger, Darrell R|Kim, Yuhree|Cosgrove, David|Ejaz, Aslam|Alexandrescu, Sorin|Groeschl, Ryan Thomas|Deshpande, Vikram|Lindberg, James M|Ferrone, Cristina|Sempoux, Christine|Yau, Thomas|Poon, Ronnie|Popescu, Irinel|Bauer, Todd W|Gamblin, T Cl | ||||||||||
| PMID: | 24889489 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncotarget. 2016 Feb 2;7(5):5306-12. | ||||||||||
| Title: | Whole-exome tumor sequencing study in biliary cancer patients with a response to MEK inhibitors. | ||||||||||
| Author: | Ahn, Daniel H|Ozer, Hatice Gulcin|Hancioglu, Baris|Lesinski, Gregory B|Timmers, Cynthia|Bekaii-Saab, Tanios | ||||||||||
| PMID: | 26683364 | ||||||||||
| 8. | |||||||||||
| Journal: | BMC Cancer. 2016 Feb 24;16:153. | ||||||||||
| Title: | A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study. | ||||||||||
| Author: | Bridgewater, John|Lopes, Andre|Beare, Sandra|Duggan, Marian|Lee, Dymphna|Ricamara, Maravic|McEntee, Delyth|Sukumaran, Ajithkumar|Wasan, Harpreet|Valle, Juan W | ||||||||||
| PMID: | 26912134 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cancer Ther. 2017 Feb;16(2):344-356. | ||||||||||
| Title: | Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities. | ||||||||||
| Author: | Talbert, Erin E|Yang, Jennifer|Mace, Thomas A|Farren, Matthew R|Farris, Alton B|Young, Gregory S|Elnaggar, Omar|Che, Zheng|Timmers, Cynthia D|Rajasekera, Priyani|Maskarinec, Jennifer M|Bloomston, Mark|Bekaii-Saab, Tanios|Guttridge, Denis C|Lesinski, Grego | ||||||||||
| PMID: | 27811010 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Cell Int. 2017 Sep 26;17:85. | ||||||||||
| Title: | Blocking ERK1/2 signaling impairs TGF-beta1 tumor promoting function but enhances its tumor suppressing role in intrahepatic cholangiocarcinoma cells. | ||||||||||
| Author: | Sritananuwat, Phaijit|Sueangoen, Natthaporn|Thummarati, Parichut|Islam, Kittiya|Suthiphongchai, Tuangporn | ||||||||||
| PMID: | 28959141 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Sci. 2018 Jan;109(1):215-224. | ||||||||||
| Title: | Efficacy and safety of trametinib in Japanese patients with advanced biliary tract cancers refractory to gemcitabine. | ||||||||||
| Author: | Ikeda, Masafumi|Ioka, Tatsuya|Fukutomi, Akira|Morizane, Chigusa|Kasuga, Akiyoshi|Takahashi, Hideaki|Todaka, Akiko|Okusaka, Takuji|Creasy, Caretha L|Gorman, Shelby|Felitsky, Daniel J|Kobayashi, Mikiro|Zhang, Fanghong|Furuse, Junji | ||||||||||
| PMID: | 29121415 | ||||||||||
| 12. | |||||||||||
| Journal: | Invest New Drugs. 2018 May 22. pii: 10.1007/s10637-018-0600-2. | ||||||||||
| Title: | Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer. | ||||||||||
| Author: | Finn, R S|Ahn, D H|Javle, M M|Tan, B R Jr|Weekes, C D|Bendell, J C|Patnaik, A|Khan, G N|Laheru, D|Chavira, R|Christy-Bittel, J|Barrett, E|Sawyer, M B|Bekaii-Saab, Tanios S | ||||||||||
| PMID: | 29785570 | ||||||||||