Primary Site >> Colorectal Cancer

Gene >> MAP1LC3B

Journal: Toxicol Appl Pharmacol. 2009 Dec 15;241(3):348-55.
Title: Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity.
Author: Honeggar, Matthew|Beck, Robert|Moos, Philip J
PMID: 19782697
Journal: Int J Mol Med. 2009 Jun;23(6):709-16.
Title: Growth inhibitory effects of vitamin K2 on colon cancer cell lines via different types of cell death including autophagy and apoptosis.
Author: Kawakita, Hideaki|Tsuchida, Akihiko|Miyazawa, Keisuke|Naito, Munekazu|Shigoka, Masatoshi|Kyo, Bunso|Enomoto, Masanobu|Wada, Tatehiko|Katsumata, Kenji|Ohyashiki, Kazuma|Itoh, Masahiro|Tomoda, Akio|Aoki, Tatsuya
PMID: 19424596
Journal: Int J Cancer. 2010 May 15;126(10):2457-68.
Title: Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells.
Author: Bijnsdorp, Irene V|Peters, Godefridus J|Temmink, Olaf H|Fukushima, Masakazu|Kruyt, Frank A
PMID: 19816940
Journal: Autophagy. 2010 Feb;6(2):256-69. Epub 2010 Feb 6.
Title: Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
Author: Huang, Shengbing|Sinicrope, Frank A
PMID: 20104024
Journal: Phytother Res. 2012 Apr;26(4):528-34.
Title: 7,7''-Dimethoxyagastisflavone-induced apoptotic or autophagic cell death in different cancer cells.
Author: Hwang, Chia-Hsiang|Lin, Yu-Ling|Liu, Yen-Ku|Chen, Chia-Hung|Wu, Hsin-Yi|Chang, Cheng-Chang|Chang, Chao-Yuan|Chang, Yu-Kuo|Chiu, Yi-Han|Liao, Kuang-Wen|Lai, Yiu-Kay
PMID: 21915931
Journal: Int J Oncol. 2012 Apr;40(4):1267-76.
Title: Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells.
Author: de Albuquerque-Xavier, Ana Cristina|Bastos, Lilian Goncalves R|de Freitas, Julio Cesar Madureira Jr|Leve, Fernanda|de Souza, Waldemir Fernandez|de Araujo, Wallace Martins|Wanderley, Joao Luiz Mendes|Tanaka, Marcelo Neves|de Souza, Wanderley|Morgado-Diaz,
PMID: 22246348
Journal: PLoS One. 2012;7(5):e37572.
Title: Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells.
Author: Wu, Ya C|Wang, Xiao J|Yu, Le|Chan, Francis K L|Cheng, Alfred S L|Yu, Jun|Sung, Joseph J Y|Wu, William K K|Cho, Chi H
PMID: 22679478
Journal: Oncol Res. 2012;20(2-3):81-91.
Title: Quinacrine-mediated autophagy and apoptosis in colon cancer cells is through a p53- and p21-dependent mechanism.
Author: Mohapatra, Purusottam|Preet, Ranjan|Das, Dipon|Satapathy, Shakti Ranjan|Choudhuri, Tathagata|Wyatt, Michael D|Kundu, Chanakya Nath
PMID: 23193914
Journal: Cancer Biol Med. 2012 Jun;9(2):105-10.
Title: Autophagy enhances the aggressiveness of human colorectal cancer cells and their ability to adapt to apoptotic stimulus.
Author: Zheng, Hai-Yang|Zhang, Xiao-Yang|Wang, Xing-Fen|Sun, Bao-Cun
PMID: 23691463
Journal: Evid Based Complement Alternat Med. 2013;2013:702869.
Title: Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy.
Author: Kwatra, Deep|Subramaniam, Dharmalingam|Ramamoorthy, Prabhu|Standing, David|Moran, Elizabeth|Velayutham, Ravichandiran|Mitra, Ashim|Umar, Shahid|Anant, Shrikant
PMID: 23533514
Journal: Biomed Res Int. 2013;2013:204973.
Title: PSF knockdown enhances apoptosis via downregulation of LC3B in human colon cancer cells.
Author: Tsukahara, Tamotsu|Matsuda, Yoshikazu|Haniu, Hisao
PMID: 24288667
Journal: Int J Oncol. 2013 Sep;43(3):927-35.
Title: Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells.
Author: Greene, Lisa M|Nolan, Derek P|Regan-Komito, Daniel|Campiani, Giuseppe|Williams, D Clive|Zisterer, Daniela M
PMID: 23799546
Journal: J Pathol. 2013 Jan;229(1):62-73.
Title: Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers.
Author: Hu, Xiaotong|Sui, Xinbing|Li, Lili|Huang, Xuefeng|Rong, Rong|Su, Xianwei|Shi, Qinglan|Mo, Lijuan|Shu, Xingsheng|Kuang, Yeye|Tao, Qian|He, Chao
PMID: 22926751
Journal: Gastroenterol Res Pract. 2014;2014:179586.
Title: Absence of autophagy-related proteins expression is associated with poor prognosis in patients with colorectal adenocarcinoma.
Author: Choi, Ji Hye|Cho, Young-Seok|Ko, Yoon Ho|Hong, Soon Uk|Park, Jin Hee|Lee, Myung Ah
PMID: 24723943
Journal: Autophagy. 2014 Jul;10(7):1229-40.
Title: New role for EMD (emerin), a key inner nuclear membrane protein, as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway.
Author: Deroyer, Celine|Renert, Anne-Francoise|Merville, Marie-Paule|Fillet, Marianne
PMID: 24819607
Journal: Br J Cancer. 2014 Jul 15;111(2):375-85.
Title: Dichloroacetate induces autophagy in colorectal cancer cells and tumours.
Author: Lin, G|Hill, D K|Andrejeva, G|Boult, J K R|Troy, H|Fong, A-C L F W T|Orton, M R|Panek, R|Parkes, H G|Jafar, M|Koh, D-M|Robinson, S P|Judson, I R|Griffiths, J R|Leach, M O|Eykyn, T R|Chung, Y-L
PMID: 24892448
Journal: Tumour Biol. 2014 Dec;35(12):12713-9.
Title: miR-204-5p expression in colorectal cancer: an autophagy-associated gene.
Author: Sumbul, Ahmet Taner|Gogebakan, Bulent|Ergun, Sercan|Yengil, Erhan|Batmaci, Celal Yucel|Tonyali, Onder|Yaldiz, Mehmet
PMID: 25209181
Journal: Yonsei Med J. 2014 Nov;55(6):1484-8.
Title: Autophagy activity in pulmonary metastatic tumor tissues from colorectal cancer: a pilot study.
Author: Kim, Young Sam|Shin, Ju Hye|Bae, Mi Kyung|Lee, Chang Young|Kim, Dae Joon|Chung, Kyung Young|Lee, Jin Gu
PMID: 25323883
Journal: Phytomedicine. 2015 May 15;22(5):536-44.
Title: Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity.
Author: Hu, Tao|Wang, Lin|Zhang, Lin|Lu, Lan|Shen, Jing|Chan, Ruby L Y|Li, Mingxing|Wu, William K K|To, Kenneth K W|Cho, Chi Hin
PMID: 25981919
Journal: Phytomedicine. 2015 Nov 15;22(12):1079-87.
Title: Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer.
Author: Wang, Lin|Hu, Tao|Shen, Jing|Zhang, Lin|Chan, Ruby Lok-Yi|Lu, Lan|Li, Mingxing|Cho, Chi Hin|Wu, William Ka Kei
PMID: 26547530
Journal: Oncol Rep. 2015 Dec;34(6):3222-30.
Title: Autophagy is upregulated during colorectal carcinogenesis, and in DNA microsatellite stable carcinomas.
Author: Sena, Paola|Mariani, Francesco|Mancini, Stefano|Benincasa, Marta|Magnani, Giulia|Pedroni, Monica|Palumbo, Carla|Roncucci, Luca
PMID: 26502823
Journal: Oncotarget. 2015 Mar 30;6(9):7084-103.
Title: Autophagy-based survival prognosis in human colorectal carcinoma.
Author: Yang, Maopeng|Zhao, Hong|Guo, Li|Zhang, Qingyuan|Zhao, Ling|Bai, Shuping|Zhang, Minghui|Xu, Sanqi|Wang, Fujing|Wang, Xiaohong|Zhao, Bin
PMID: 25762626
Journal: Colloids Surf B Biointerfaces. 2015 Nov 1;135:793-801.
Title: Novel self-micellizing anticancer lipid nanoparticles induce cell death of colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Baskaran, Rengarajan|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Oh, Seung Hyun|Kyu Yoo, Bong|Kim, Hwan Mook
PMID: 26342325
Journal: BMC Cancer. 2016 Jan 16;16:23.
Title: A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells.
Author: Dutta, Debasmita|Chakraborty, Biswajit|Sarkar, Ankita|Chowdhury, Chinmay|Das, Padma
PMID: 26772983
Journal: Mol Med Rep. 2016 Mar;13(3):2661-70.
Title: Effects of autophagy regulation of tumor-associated macrophages on radiosensitivity of colorectal cancer cells.
Author: Shao, Le-Ning|Zhu, Bao-Song|Xing, Chun-Gen|Yang, Xiao-Dong|Young, Wu|Cao, Jian-Ping
PMID: 26821367
Journal: Am J Cancer Res. 2016 Aug 1;6(8):1661-80. eCollection 2016.
Title: EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells.
Author: Hsieh, Yao-Yu|Lo, Hsiang-Ling|Yang, Pei-Ming
PMID: 27648357
Journal: Oncotarget. 2017 May 2;8(33):54604-54615.
Title: Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.
Author: Niklaus, Monique|Adams, Olivia|Berezowska, Sabina|Zlobec, Inti|Graber, Franziska|Slotta-Huspenina, Julia|Nitsche, Ulrich|Rosenberg, Robert|Tschan, Mario P|Langer, Rupert
PMID: 28903368
Journal: BMC Complement Altern Med. 2017 Dec 16;17(1):538.
Title: Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer.
Author: Li, Hai|Chen, Chen
PMID: 29246220
Journal: Oncotarget. 2017 Aug 3;8(51):88563-88574.
Title: Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death.
Author: Chen, Shun-Ting|Lee, Tzung-Yan|Tsai, Tung-Hu|Huang, Yu-Chuen|Lin, Yin-Cheng|Lin, Chin-Ping|Shieh, Hui-Ru|Hsu, Ming-Ling|Chi, Chih-Wen|Lee, Ming-Cheng|Chang, Hen-Hong|Chen, Yu-Jen
PMID: 29179457
Journal: Sci Rep. 2017 Oct 24;7(1):13912.
Title: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author: Dai, Lianzhi|Chen, Xiaolei|Lu, Xiaohong|Wang, Fen|Zhan, Yanyan|Song, Gang|Hu, Tianhui|Xia, Chun|Zhang, Bing
PMID: 29066806
Journal: Cell Death Dis. 2017 Aug 24;8(8):e3019.
Title: AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells.
Author: Seiwert, Nina|Neitzel, Carina|Stroh, Svenja|Frisan, Teresa|Audebert, Marc|Toulany, Mahmoud|Kaina, Bernd|Fahrer, Jorg
PMID: 28837154
Journal: Life Sci. 2017 Sep 15;185:63-72.
Title: M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway.
Author: Peng, Ying|Qiu, Ling|Xu, Dong|Zhang, Li|Yu, Huixin|Ding, Yuedi|Deng, Lili|Lin, Jianguo
PMID: 28751160
Journal: Eur J Pharm Biopharm. 2017 Aug;117:346-362.
Title: Curcumin loading potentiates the chemotherapeutic efficacy of selenium nanoparticles in HCT116 cells and Ehrlich's ascites carcinoma bearing mice.
Author: Kumari, Manisha|Ray, L|Purohit, M P|Patnaik, S|Pant, A B|Shukla, Y|Kumar, P|Gupta, K C
PMID: 28499854
Journal: Oncotarget. 2017 Feb 28;8(9):14736-14747.
Title: AMPK-autophagy inhibition sensitizes icaritin-induced anti-colorectal cancer cell activity.
Author: Zhou, Chunxian|Gu, Jun|Zhang, Gang|Dong, Da|Yang, Qunying|Chen, Min-Bin|Xu, Dongfeng
PMID: 28103582
Journal: J Cell Biochem. 2018 Apr;119(4):3763-3774.
Title: Hyperthermia enhances radiosensitivity of colorectal cancer cells through ROS inducing autophagic cell death.
Author: Ba, Ming-Chen|Long, Hui|Wang, Shuai|Wu, Yin-Bing|Zhang, Bo-Huo|Yan, Zhao-Fei|Yu, Fei-Hong|Cui, Shu-Zhong
PMID: 29240246
Journal: Photodiagnosis Photodyn Ther. 2018 Mar;21:396-403.
Title: Inhibition of autophagy potentiates the apoptosis-inducing effects of photodynamic therapy on human colon cancer cells.
Author: Ouyang, Guoqing|Xiong, Li|Liu, Zhipeng|Lam, Brandon|Bui, Brian|Ma, Lun|Chen, Xiang|Zhou, Pan|Wang, Kunpeng|Zhang, Zijian|Huang, He|Miao, Xiongying|Chen, Wei|Wen, Yu
PMID: 29355734
Journal: FEBS J. 2018 Jul;285(13):2446-2467.
Title: Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells.
Author: Samdal, Helle|Sandmoe, Malin A|Olsen, Lene C|Jarallah, Elaf A H|Hoiem, Therese S|Schonberg, Svanhild A|Pettersen, Caroline H H
PMID: 29723445
Journal: Discov Med. 2018 Jun;25(140):265-275.
Title: miR-212 and mTOR form a regulation loop to modulate autophagy in colorectal adenoma HT-29 cells.
Author: Ji, Changxue|Ju, Shuai|Qiang, Jinwei
PMID: 30021100
Journal: Med Oncol. 2018 Oct 29;35(12):159.
Title: The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients.
Author: Gil, Justyna|Ramsey, David|Pawlowski, Pawel|Szmida, Elzbieta|Leszczynski, Przemyslaw|Bebenek, Marek|Sasiadek, Maria M
PMID: 30374741