Primary Site >> Pancreatic Cancer

Gene >> LRRK2

Journal: Mol Cancer. 2014 May 6;13:103.
Title: Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
Author: Weygant, Nathaniel|Qu, Dongfeng|Berry, William L|May, Randal|Chandrakesan, Parthasarathy|Owen, Daniel B|Sureban, Sripathi M|Ali, Naushad|Janknecht, Ralf|Houchen, Courtney W
PMID: 24885928
Journal: Oncol Rep. 2017 Nov;38(5):3238-3244.
Title: Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells.
Author: Kawamura, Daichi|Takemoto, Yoshihiro|Nishimoto, Arata|Ueno, Koji|Hosoyama, Tohru|Shirasawa, Bungo|Tanaka, Toshiki|Kugimiya, Naruji|Harada, Eijiro|Hamano, Kimikazu
PMID: 29048622