Primary Site >> Colorectal Cancer

Gene >> LCN2

Journal: Cancer Lett. 2004 Mar 31;206(1):107-13.
Title: Wnt inhibitory factor-1: a candidate for a new player in tumorigenesis of intestinal epithelial cells.
Author: Cebrat, Malgorzata|Strzadala, Leon|Kisielow, Pawel
PMID: 15019166
Journal: Cancer Res. 2005 Jan 1;65(1):166-76.
Title: Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors.
Author: Reichling, Tim|Goss, Kathleen Heppner|Carson, Daniel J|Holdcraft, Robert W|Ley-Ebert, Cathy|Witte, Dave|Aronow, Bruce J|Groden, Joanna
PMID: 15665292
Journal: Mol Cell Proteomics. 2006 Aug;5(8):1471-83.
Title: Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.
Author: Madoz-Gurpide, Juan|Lopez-Serra, Paula|Martinez-Torrecuadrada, Jorge Luis|Sanchez, Lydia|Lombardia, Luis|Casal, J Ignacio
PMID: 16733264
Journal: Int J Cancer. 2006 May 15;118(10):2490-7.
Title: Ectopic expression of neutrophil gelatinase-associated lipocalin suppresses the invasion and liver metastasis of colon cancer cells.
Author: Lee, Ho-Jeong|Lee, Eun-Kyoung|Lee, Kong-Ju|Hong, Soon-Won|Yoon, Yeup|Kim, Jang-Seong
PMID: 16381001
Journal: Orv Hetil. 2007 Nov 4;148(44):2067-79.
Title: [Identification of colorectal cancer, adenoma, and inflammatory bowel disease specific gene expression patterns using whole genomic oligonucleotide microarray system].
Author: Galamb, Orsolya|Gyorffy, Balazs|Sipos, Ferenc|Spisak, Sandor|Nemeth, Anna Maria|Miheller, Pal|Dinya, Elek|Molnar, Bela|Tulassay, Zsolt
PMID: 17959550
Journal: Dis Markers. 2008;25(1):1-16.
Title: Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature.
Author: Galamb, Orsolya|Gyorffy, Balazs|Sipos, Ferenc|Spisak, Sandor|Nemeth, Anna Maria|Miheller, Pal|Tulassay, Zsolt|Dinya, Elek|Molnar, Bela
PMID: 18776587
Journal: Int J Cancer. 2008 Dec 15;123(12):2856-64.
Title: Identification of new accessible tumor antigens in human colon cancer by ex vivo protein biotinylation and comparative mass spectrometry analysis.
Author: Conrotto, Paolo|Roesli, Christoph|Rybak, Jascha|Kischel, Philippe|Waltregny, David|Neri, Dario|Castronovo, Vincent
PMID: 18798264
Journal: Lab Invest. 2009 May;89(5):531-48.
Title: NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells.
Author: Hu, Limei|Hittelman, Walter|Lu, Tao|Ji, Ping|Arlinghaus, Ralph|Shmulevich, Ilya|Hamilton, Stanley R|Zhang, Wei
PMID: 19308044
Journal: BMC Cancer. 2009 May 6;9:134.
Title: Clinical significance of Neutrophil gelatinase-associated lipocalin(NGAL) expression in primary rectal cancer.
Author: Zhang, Xiu-Feng|Zhang, Ying|Zhang, Xiao-Hua|Zhou, Su-Mei|Yang, Guan-Gen|Wang, Ou-Chen|Guo, Gui-Long|Yang, Gao-Yi|Hu, Xiao-Qu
PMID: 19419554
Journal: Int J Oncol. 2010 Jun;36(6):1485-90.
Title: Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis.
Author: Bousserouel, Souad|Kauntz, Henriette|Gosse, Francine|Bouhadjar, Mourad|Soler, Luc|Marescaux, Jacques|Raul, Francis
PMID: 20428773
Journal: Oncol Lett. 2010 Nov;1(6):1089-1096.
Title: Neutrophil gelatinase-associated lipocalin immunoexpression in colorectal carcinoma: A stage-specific prognostic factor?
Author: Barresi, Valeria|Luciano, Roberta|Vitarelli, Enrica|Labate, Agata|Tuccari, Giovanni|Barresi, Gaetano
PMID: 22870118
Journal: Oncol Lett. 2010 Jan;1(1):103-108.
Title: Overexpression of neutrophil gelatinase-associated lipocalin and its receptor in colorectal carcinoma: Significant correlation with cell differentiation and tumour invasion.
Author: Lv, Zhuo|Xu, Li-Yan|Shen, Zhong-Ying|Zhang, Fa-Ren|Xu, Xiu-E|Li, En-Min
PMID: 22966265
Journal: J Nutr Biochem. 2011 Jul;22(7):634-41.
Title: Up-regulation of the novel proinflammatory adipokines lipocalin-2, chitinase-3 like-1 and osteopontin as well as angiogenic-related factors in visceral adipose tissue of patients with colon cancer.
Author: Catalan, Victoria|Gomez-Ambrosi, Javier|Rodriguez, Amaia|Ramirez, Beatriz|Silva, Camilo|Rotellar, Fernando|Hernandez-Lizoain, Jose L|Baixauli, Jorge|Valenti, Victor|Pardo, Fernando|Salvador, Javier|Fruhbeck, Gema
PMID: 20961744
Journal: Pathol Res Pract. 2011 Aug 15;207(8):479-86.
Title: Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) prognostic value in stage I colorectal carcinoma.
Author: Barresi, Valeria|Reggiani-Bonetti, Luca|Di Gregorio, Carmela|Vitarelli, Enrica|Ponz De Leon, Maurizio|Barresi, Gaetano
PMID: 21726963
Journal: Clin Cancer Res. 2011 Jul 1;17(13):4331-40.
Title: NGAL expression is elevated in both colorectal adenoma-carcinoma sequence and cancer progression and enhances tumorigenesis in xenograft mouse models.
Author: Sun, Yan|Yokoi, Kenji|Li, Hui|Gao, Jun|Hu, Limei|Liu, Ben|Chen, Kexin|Hamilton, Stanley R|Fan, Dominic|Sun, Baocun|Zhang, Wei
PMID: 21622717
Journal: Hum Pathol. 2011 Nov;42(11):1720-6.
Title: Neutrophil gelatinase-associated lipocalin: a new prognostic marker in stage I colorectal carcinoma?
Author: Barresi, Valeria|Di Gregorio, Carmela|Reggiani-Bonetti, Luca|Ieni, Antonio|Ponz-De Leon, Maurizio|Barresi, Gaetano
PMID: 21420718
Journal: Pathol Int. 2011 Feb;61(2):80-7.
Title: Early modulation of gene expression used as a biomarker for chemoprevention in a preclinical model of colon carcinogenesis.
Author: Bousserouel, Souad|Lamy, Virginie|Gosse, Francine|Lobstein, Annelise|Marescaux, Jacques|Raul, Francis
PMID: 21255184
Journal: Mol Cancer Res. 2011 Feb;9(2):133-48.
Title: S100A8/A9 activate key genes and pathways in colon tumor progression.
Author: Ichikawa, Mie|Williams, Roy|Wang, Ling|Vogl, Thomas|Srikrishna, Geetha
PMID: 21228116
Journal: Biochim Biophys Acta. 2012 Aug;1826(1):129-69.
Title: The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer.
Author: Chakraborty, Subhankar|Kaur, Sukhwinder|Guha, Sushovan|Batra, Surinder K
PMID: 22513004
Journal: Oncotarget. 2012 Oct;3(10):1236-45.
Title: Effects of ectopic expression of NGAL on doxorubicin sensitivity.
Author: Chappell, William H|Abrams, Stephen L|Montalto, Giuseppe|Cervello, Melchiorre|Martelli, Alberto M|Candido, Saverio|Libra, Massimo|Polesel, Jerry|Talamini, Renato|Arlinghaus, Ralph|Steelman, Linda S|McCubrey, James A
PMID: 23100449
Journal: Cell Cycle. 2012 Dec 1;11(23):4447-61.
Title: Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.
Author: Chappell, William H|Abrams, Stephen L|Franklin, Richard A|LaHair, Michelle M|Montalto, Giuseppe|Cervello, Melchiorre|Martelli, Alberto M|Nicoletti, Ferdinando|Candido, Saverio|Libra, Massimo|Polesel, Jerry|Talamini, Renato|Milella, Michele|Tafuri, Agostin
PMID: 23159854
Journal: Cancer Biomark. 2013;13(2):75-9.
Title: Performance of serum lipocalin 2 as a diagnostic marker for colorectal cancer.
Author: Fung, Kim Y C|Priebe, Ilka|Purins, Leanne|Tabor, Bruce|Brierley, Gemma V|Lockett, Trevor|Nice, Edouard|Gibbs, Peter|Tie, Jeannie|McMurrick, Paul|Moore, James|Ruszkiewicz, Andrew|Burgess, Antony|Cosgrove, Leah J
PMID: 23838135
Journal: Br J Cancer. 2013 Jun 25;108(12):2537-41.
Title: Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
Author: McLean, M H|Thomson, A J|Murray, G I|Fyfe, N|Hold, G L|El-Omar, E M
PMID: 23736029
Journal: Oncogene. 2013 Mar 7;32(10):1233-9.
Title: Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression.
Author: Reilly, P T|Teo, W L|Low, M J|Amoyo-Brion, A A|Dominguez-Brauer, C|Elia, A J|Berger, T|Greicius, G|Pettersson, S|Mak, T W
PMID: 22614012
Journal: World J Surg. 2013 May;37(5):1103-9.
Title: Prognostic value of serum neutrophil gelatinase-associated lipocalin in metastatic and nonmetastatic colorectal cancer.
Author: Marti, Josep|Fuster, Josep|Sola, Anna M|Hotter, Georgina|Molina, Rafael|Pelegrina, Amalia|Ferrer, Joana|Deulofeu, Ramon|Fondevila, Constantino|Garcia-Valdecasas, Juan Carlos
PMID: 23389669
Journal: J Gastroenterol Hepatol. 2014 May;29(5):957-63.
Title: Effects of dietary supplementation of glucosamine sulfate on intestinal inflammation in a mouse model of experimental colitis.
Author: Bak, Youn-Kyung|Lampe, Johanna W|Sung, Mi-Kyung
PMID: 24325781
Journal: Genet Mol Res. 2014 Feb 21;13(3):7102-12.
Title: Clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) in colorectal cancer: a meta-analysis.
Author: Wang, Y|Zeng, T T
PMID: 24634297
Journal: World J Surg. 2014 Aug;38(8):2160-7.
Title: Up-regulation of neutrophil gelatinase-associated lipocalin in colorectal cancer predicts poor patient survival.
Author: Maier, Herbert Thomas|Aigner, Felix|Trenkwalder, Birgit|Zitt, Matthias|Vallant, Natalie|Perathoner, Alexander|Margreiter, Christian|Moser, Patrizia|Pratschke, Johann|Amberger, Albert
PMID: 24682311
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jun;17(6):589-93.
Title: [Clinical significance of the detection of serum neutrophil gelatinase-associated lipocalin in human colorectal cancer].
Author: Ding, Lei|Zhang, Xiufeng|Zhang, Yanxiang|Yang, Guangen|Liao, Xiujun|Shen, Zhong|Qiu, Jianming|Mao, Weiming|Hu, Lihua|Shao, Shuxian|Shang, Shanliang
PMID: 24953369
Journal: Int J Clin Exp Med. 2014 Sep 15;7(9):2804-11. eCollection 2014.
Title: Role of human neutrophil gelatinase associated lipocalin (NGAL) and Matrix Metalloproteinase-9 (MMP-9) overexpression in neoplastic colon polyps.
Author: Odabasi, Mehmet|Yesil, Atakan|Ozkara, Selvinaz|Paker, Nurcan|Ozkan, Sevil|Eris, Cengiz|Yildiz, Mehmet Kamil|Abuoglu, Haci Hasan|Gunay, Emre|Tekesin, Kemal
PMID: 25356142
Journal: BMC Cancer. 2014 Dec 3;14:912.
Title: A case-control study of pre-operative levels of serum neutrophil gelatinase-associated lipocalin and other potential inflammatory markers in colorectal cancer.
Author: Duvillard, Laurence|Ortega-Deballon, Pablo|Bourredjem, Abderrahmane|Scherrer, Marie-Lorraine|Mantion, Georges|Delhorme, Jean-Baptiste|Deguelte-Lardiere, Sophie|Petit, Jean-Michel|Bonithon-Kopp, Claire
PMID: 25472811
Journal: Neuroreport. 2015 Sep 30;26(14):870-6.
Title: Ontogenic expression profiles and oxaliplatin regulation of leptin expression in mice dorsal root ganglion.
Author: Chen, Hongping|Wang, Qinghua|Lei, Qiongqiong|Zhang, Lei|Kang, Lumei
PMID: 26302162
Journal: Int J Clin Exp Pathol. 2015 Mar 1;8(3):2888-98. eCollection 2015.
Title: Biomarkers of erlotinib response in non-small cell lung cancer tumors that do not harbor the more common epidermal growth factor receptor mutations.
Author: Lopez-Ayllon, Blanca D|de Castro-Carpeno, Javier|Rodriguez, Carlos|Pernia, Olga|Ibanez de Caceres, Inmaculada|Belda-Iniesta, Cristobal|Perona, Rosario|Sastre, Leandro
PMID: 26045797
Journal: Tumour Biol. 2015 Aug;36(8):6011-8.
Title: Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon cancer in order to inhibit liver metastasis in nude mice.
Author: Harati, Mozhgan Dehghan|Amiri, Fatemeh|Jaleh, Fatemeh|Mehdipour, Ahmad|Harati, Mitra Dehghan|Molaee, Sedigheh|Bahadori, Marzieh|Shokrgozar, Mohammad Ali|Jalili, Mohammad Ali|Roudkenar, Mehryar Habibi
PMID: 25740061
Journal: Asian Pac J Cancer Prev. 2015;16(2):407-10.
Title: Predictive role of neutrophil gelatinase-associated lipocalin in early diagnosis of platin-induced renal injury.
Author: Seker, Mehmet Metin|Deveci, Koksal|Seker, Ayse|Sancakdar, Enver|Yilmaz, Ali|Turesin, A Kerim|Kacan, Turgut|Babacan, Nalan A
PMID: 25684463
Journal: Pharmacogenet Genomics. 2015 Jan;25(1):30-7.
Title: Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.
Author: Sebio, Ana|Gerger, Armin|Matsusaka, Satoshi|Yang, Dongyun|Zhang, Wu|Stremitzer, Stefan|Stintzing, Sebastian|Sunakawa, Yu|Yamauchi, Shinichi|Ning, Yan|Fujimoto, Yoshiya|Ueno, Masashi|Lenz, Heinz-Josef
PMID: 25379721
Journal: Biochem Biophys Res Commun. 2016 Aug 5;476(4):286-292.
Title: Proteomic analysis of minute amount of colonic biopsies by enteroscopy sampling.
Author: Liu, Xing|Xu, Yanli|Meng, Qian|Zheng, Qingqing|Wu, Jianhong|Wang, Chen|Jia, Weiping|Figeys, Daniel|Chang, Ying|Zhou, Hu
PMID: 27230957
Journal: Postepy Hig Med Dosw (Online). 2016 Jan 4;70(0):1026-1031.
Title: Role of oncogene 24p3 neutrophil gelatinase-associated lipocalin (NGAL) in digestive system cancers.
Author: Michalak, Lukasz|Bulska, Magdalena|Kudlacz, Katarzyna|Szczesniak, Piotr
PMID: 27708207
Journal: Chirurgia (Bucur). 2016 Sept-Oct;111(5):414-421.
Title: The Diagnostic and Prognostic Significance of Serum Neutrophil Gelatinase-Associated Lipocalin Levels in Patients with Colorectal Cancer.
Author: Ozemir, Ibrahim Ali|Aslan, Sinan|Eren, Tunc|Bayraktar, Baris|Bilgic, Cagri|Isbilen, Banu|Yalman, Haydar|Yigitbasi, Rafet|Alimoglu, Orhan
PMID: 27819647
Journal: Mol Cancer. 2016 Dec 3;15(1):77.
Title: Lipocalin2 suppresses metastasis of colorectal cancer by attenuating NF-kappaB-dependent activation of snail and epithelial mesenchymal transition.
Author: Feng, Meibao|Feng, Jieqiong|Chen, Wuzhen|Wang, Wubin|Wu, Xuesong|Zhang, Jing|Xu, Fangying|Lai, Maode
PMID: 27912767
Journal: Int J Biol Markers. 2017 Mar 2;32(1):e53-e61.
Title: Can NGAL be employed as prognostic and diagnostic biomarker in human cancers? A systematic review of current evidence.
Author: Roli, Laura|Pecoraro, Valentina|Trenti, Tommaso
PMID: 28106227
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jun 25;20(6):694-700.
Title: [Experimental research of neutrophil gelatinase-associated lipocalin siRNA encapsulated by urocanic acid-coupled chitosan on colon cancer cells].
Author: Shen, Zhong|Xu, Kan|Wang, Houdong|Yang, Guangen|Pan, Jieli|Li, Meiya|Qiu, Jianming|Wu, Wenjing|Zhang, Ying|Zhang, Xiufeng
PMID: 28643318
Journal: Cancer Sci. 2017 Nov;108(11):2176-2186.
Title: Lipocalin 2 negatively regulates cell proliferation and epithelial to mesenchymal transition through changing metabolic gene expression in colorectal cancer.
Author: Kim, Se-Lim|Lee, Soo Teik|Min, In Suk|Park, Young Ran|Lee, Ju Hyung|Kim, Dae-Ghon|Kim, Sang-Wook
PMID: 28859238
Journal: Curr Opin Gastroenterol. 2017 Nov;33(6):422-427.
Title: Novel insights into microbiome in colitis and colorectal cancer.
Author: Yang, Ye|Jobin, Christian
PMID: 28877044
Journal: Recent Pat Anticancer Drug Discov. 2018;13(2):248-254.
Title: Reduced Lipocalin 2 Expression Contributes to Vincristine Resistance in Human Colon Cancer Cells.
Author: Guo, Xiao|Li, Qin|Wang, Yan-Fang|Wang, Tian-Yun|Chen, Si-Jia|Tian, Zheng-Wei
PMID: 29268690
Journal: Oncotarget. 2018 Jul 20;9(56):30761-30772.
Title: NGAL promotes recruitment of tumor infiltrating leukocytes.
Author: Pacifico, Francesco|Pisa, Luna|Mellone, Stefano|Cillo, Michele|Lepore, Alessio|Leonardi, Antonio
PMID: 30112105
Journal: Int J Oncol. 2018 Sep 14.
Title: Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer.
Author: Kim, Se-Lim|Min, In Suk|Park, Young Ran|Lee, Soo Teik|Kim, Sang-Wook
PMID: 30221676