Primary Site >> Colorectal Cancer

Gene >> KRT8

Journal: Int J Cancer. 1990 Oct 15;46(4):604-7.
Title: A two-site enzyme-linked immunosorbent assay for cytokeratin 8.
Author: Sundstrom, B|Stigbrand, T
PMID: 1698728
Journal: Int J Cancer. 1992 Feb 20;50(4):562-6.
Title: Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies.
Author: Ljubimov, A V|Bartek, J|Couchman, J R|Kapuller, L L|Veselov, V V|Kovarik, J|Perevoshchikov, A G|Krutovskikh, V A
PMID: 1371500
Journal: Anticancer Res. 1992 Jul-Aug;12(4):1121-9.
Title: Application of anti lung adenocarcinoma monoclonal antibody recognizing cytokeratin-like cytoplasmic antigen for tumor diagnosis.
Author: Shitara, K|Fujiwara, K|Kusano, A|Yamaguchi, K|Yoshida, H|Sato, S|Hanai, N
PMID: 1503402
Journal: Cancer Res. 1996 Jun 15;56(12):2752-7.
Title: Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments.
Author: Nishibori, H|Matsuno, Y|Iwaya, M|Osada, T|Kubomura, N|Iwamatsu, A|Kohno, H|Sato, S|Kitajima, M|Hirohashi, S
PMID: 8665509
Journal: Hum Pathol. 1998 Feb;29(2):119-26.
Title: Keratin subsets and monoclonal antibody HBME-1 in chordoma: immunohistochemical differential diagnosis between tumors simulating chordoma.
Author: O'Hara, B J|Paetau, A|Miettinen, M
PMID: 9490269
Journal: Gastroenterology. 1999 Oct;117(4):858-65.
Title: Clonogenic growth of epithelial cells from normal colonic mucosa from both mice and humans.
Author: Whitehead, R H|Demmler, K|Rockman, S P|Watson, N K
PMID: 10500068
Journal: Oncogene. 2000 Aug 24;19(36):4125-33.
Title: Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.
Author: Clarke, P A|Hostein, I|Banerji, U|Stefano, F D|Maloney, A|Walton, M|Judson, I|Workman, P
PMID: 10962573
Journal: Lab Invest. 2001 Oct;81(10):1351-61.
Title: Transcription of cytokeratins 8, 18, and 19 in bone marrow and limited expression of cytokeratins 7 and 20 by carcinoma cells: inherent limitations for RT-PCR in the detection of isolated tumor cells.
Author: Dimmler, A|Gerhards, R|Betz, C|Gunther, K|Reingruber, B|Horbach, T|Baumann, I|Kirchner, T|Hohenberger, W|Papadopoulos, T
PMID: 11598148
Journal: J Biol Chem. 2002 Jun 14;277(24):21712-22.
Title: Cancer-associated cleavage of cytokeratin 8/18 heterotypic complexes exposes a neoepitope in human adenocarcinomas.
Author: Ditzel, Henrik J|Strik, Merel C M|Larsen, Morten K|Willis, Antony C|Waseem, Ahmad|Kejling, Karin|Jensenius, Jens C
PMID: 11923318
Journal: Int J Cancer. 2005 Apr 10;114(3):433-5.
Title: Association between mutations in the CARD15/NOD2 gene and colorectal cancer in a Greek population.
Author: Papaconstantinou, Ioannis|Theodoropoulos, George|Gazouli, Maria|Panoussopoulos, Dimitris|Mantzaris, Gerassimos J|Felekouras, Evangelos|Bramis, John
PMID: 15578724
Journal: DNA Cell Biol. 2005 Jan;24(1):21-9.
Title: Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS.
Author: Ramsay, Robert G|Ciznadija, Daniel|Sicurella, Catherine|Reyes, Nancy|Mitchelhill, Ken|Darcy, Phillip K|D'Abaco, Giovanna|Mantamadiotis, Theo
PMID: 15684716
Journal: Mol Cancer. 2006 May 18;5:20.
Title: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery.
Author: De Angelis, Paula M|Svendsrud, Debbie H|Kravik, Katherine L|Stokke, Trond
PMID: 16709241
Journal: Cancer Res. 2006 Jul 1;66(13):6553-62.
Title: Proteomic analysis reveals field-wide changes in protein expression in the morphologically normal mucosa of patients with colorectal neoplasia.
Author: Polley, Abigael C J|Mulholland, Francis|Pin, Carmen|Williams, Elizabeth A|Bradburn, D Mike|Mills, Sarah J|Mathers, John C|Johnson, Ian T
PMID: 16818627
Journal: Scand J Gastroenterol. 2006 Sep;41(9):1073-8.
Title: RT-PCR and immunohistochemical evaluation of sentinel lymph nodes after in vivo mapping with Patent Blue V in colon cancer patients.
Author: Kelder, Wendy|van den Berg, Anke|van der Leij, Judith|Bleeker, Wim|Tiebosch, Anton T M G|Grond, Joris K|Baas, Peter C|Plukker, John Th
PMID: 16938721
Journal: Cell Oncol. 2006;28(4):167-75.
Title: Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays.
Author: Knosel, Thomas|Emde, Valeska|Schluns, Karsten|Schlag, Peter Michael|Dietel, Manfred|Petersen, Iver
PMID: 16988472
Journal: Int J Cancer. 2006 Dec 15;119(12):2958-69.
Title: Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence.
Author: Akare, Sandeep|Jean-Louis, Samira|Chen, Wemin|Wood, Daniel J|Powell, Ashley A|Martinez, Jesse D
PMID: 17019713
Journal: Med Clin (Barc). 2007 Sep 15;129(9):333-4.
Title: [Detection and quantification of circulating tumor cells in peripheral blood in patients with colon cancer].
Author: Vidaurreta, Marta|Sastre, Javier|Sanz-Casla, Maria Teresa|Maestro, Maria Luisa|Rafael, Sara|Diaz-Rubio, Eduardo
PMID: 17910847
Journal: Int J Mol Med. 2008 Oct;22(4):465-72.
Title: Characterization of colon carcinoma growth pattern by computerized morphometry: definition of a complexity index.
Author: Franzen, L E|Hahn-Stromberg, V|Edvardsson, H|Bodin, L
PMID: 18813853
Journal: Proteomics. 2008 Jan;8(2):279-88.
Title: Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis.
Author: Leech, Sian H|Evans, Caroline A|Shaw, Leila|Wong, Chi H|Connolly, Joanne|Griffiths, John R|Whetton, Anthony D|Corfe, Bernard M
PMID: 18203277
Journal: Oncol Rep. 2008 Jul;20(1):89-98.
Title: Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry.
Author: Wong, Cesar Sze-Chuen|Wong, Vicky Wai-Ki|Chan, Charles Ming-Lok|Ma, Brigette Buig-Yue|Hui, Edwin Pun|Wong, Manson Chi-Keung|Lam, Money Yan-Yee|Au, Thomas Chi-Chuen|Chan, Wing-Han|Cheuk, Wah|Chan, Anthony Tak-Cheung
PMID: 18575723
Journal: Int J Cancer. 2009 Apr 15;124(8):1802-10.
Title: Down-modulation of keratin 8 phosphorylation levels by PRL-3 contributes to colorectal carcinoma progression.
Author: Mizuuchi, Eri|Semba, Shuho|Kodama, Yoshinori|Yokozaki, Hiroshi
PMID: 19115206
Journal: Eur J Surg Oncol. 2010 Apr;36(4):428; author reply 429.
Title: Anti-Cytokeratin (CAM5.2) reagent directed against cytokeratin 8, not cytokeratin 18. Comment on "Improving staging accuracy in colon and rectal cancer by sentinel lymph node mapping: a comparative study. Eur J Surg Oncol. 2009; 35: 1065-1070.".
Author: Lin, C K|Yao, C C|Tseng, S W|Han, C P
PMID: 20133104
Journal: Exp Ther Med. 2010 Jan;1(1):9-12.
Title: Circulating cytokeratin 18 fragments and activation of dormant tumor cells in bone marrow of cancer patients.
Author: Ausch, Christoph|Buxhofer-Ausch, Veronika|Olszewski, Ulrike|Hamilton, Gerhard
PMID: 23136585
Journal: ISRN Mol Biol. 2012 Jan 31;2012:706545.
Title: Increased Phospho-Keratin 8 Isoforms in Colorectal Tumors Associated with EGFR Pathway Activation and Reduced Apoptosis.
Author: Arentz, Georgia|Chataway, Tim|Condina, Mark R|Price, Timothy J|Hoffmann, Peter|Hardingham, Jennifer E
PMID: 27398237
Journal: J Proteomics. 2013 May 27;83:15-25.
Title: Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells.
Author: Rufino-Palomares, Eva E|Reyes-Zurita, Fernando J|Garcia-Salguero, Leticia|Mokhtari, Khalida|Medina, Pedro P|Lupianez, Jose A|Peragon, Juan
PMID: 23499989
Journal: Cell Oncol (Dordr). 2013 Jul;36(4):289-301.
Title: In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.
Author: Peran, Macarena|Marchal, Juan Antonio|Garcia, Maria A|Kenyon, Julian|Tosh, David
PMID: 23677639
Journal: Bioorg Med Chem Lett. 2013 Jul 1;23(13):3769-74.
Title: Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells.
Author: Min, Garam|Lee, Su-Kyung|Kim, Hye-Nan|Han, Young-Min|Lee, Rhan-Hee|Jeong, Dae Gwin|Han, Dong Cho|Kwon, Byoung-Mog
PMID: 23726031
Journal: J Cancer Res Ther. 2014 Jan-Mar;10(1):89-96.
Title: Proteomic analysis reveals novel proteins associated with progression and differentiation of colorectal carcinoma.
Author: Gan, Yi|Chen, Daojin|Li, Xiaorong
PMID: 24762493
Journal: Int J Mol Med. 2014 Jan;33(1):194-200.
Title: P7 peptides targeting bFGF sensitize colorectal cancer cells to CPT-11.
Author: Luo, Wu|Yu, Yonglin|Wang, Ruixue|He, Dan|Wang, Cong|Zeng, Xiangfeng|Chen, Xilei|Tan, Xiangpeng|Huang, Tao|Wu, Xiaoping
PMID: 24190390
Journal: Cancer Lett. 2015 Mar 1;358(1):43-6.
Title: Cytokeratin 20 improves the detection of circulating tumor cells in patients with colorectal cancer.
Author: Welinder, Charlotte|Jansson, Bo|Lindell, Gert|Wenner, Jorgen
PMID: 25528628
Journal: Cancer Biol Ther. 2015;16(5):699-708.
Title: Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: a prospective trial with different detection techniques.
Author: Kaifi, Jussuf T|Kunkel, Miriam|Das, Avisnata|Harouaka, Ramdane A|Dicker, David T|Li, Guangfu|Zhu, Junjia|Clawson, Gary A|Yang, Zhaohai|Reed, Michael F|Gusani, Niraj J|Kimchi, Eric T|Staveley-O'Carroll, Kevin F|Zheng, Si-Yang|El-Deiry, Wafik S
PMID: 25807199
Journal: Zhonghua Zhong Liu Za Zhi. 2015 Mar;37(3):165-9.
Title: [Screening of citrullinated proteins in ten tumor cell lines].
Author: Zhang, Wei|Ma, Lining|Sui, Yun|Chang, Xiaotian
PMID: 25975782
Journal: Oncol Rep. 2015 Oct;34(4):1933-42.
Title: Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells.
Author: Chaiyawat, Parunya|Chokchaichamnankit, Daranee|Lirdprapamongkol, Kriengsak|Srisomsap, Chantragan|Svasti, Jisnuson|Champattanachai, Voraratt
PMID: 26252736
Journal: J Hum Genet. 2016 Aug;61(8):711-20.
Title: Claudin-7 indirectly regulates the integrin/FAK signaling pathway in human colon cancer tissue.
Author: Ding, Lei|Wang, Liyong|Sui, Leiming|Zhao, Huanying|Xu, Xiaoxue|Li, Tengyan|Wang, Xiaonan|Li, Wenjing|Zhou, Ping|Kong, Lu
PMID: 27121327
Journal: Carcinogenesis. 2016 Aug;37(8):777-786.
Title: Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway.
Author: Misiorek, Julia O|Lahdeniemi, Iris A K|Nystrom, Joel H|Paramonov, Valeriy M|Gullmets, Josef A|Saarento, Helena|Rivero-Muller, Adolfo|Husoy, Trine|Taimen, Pekka|Toivola, Diana M
PMID: 27234655
Journal: Medicine (Baltimore). 2017 Sep;96(38):e7466.
Title: Cronkhite-Canada syndrome associated with colon cancer metastatic to liver: A case report.
Author: Wang, Jing|Zhao, Lei|Ma, Nina|Che, Juanjuan|Li, Huihui|Cao, Bangwei
PMID: 28930817
Journal: Oncotarget. 2017 May 27;8(57):96774-96790.
Title: Keratin 8 reduces colonic permeability and maintains gut microbiota homeostasis, protecting against colitis and colitis-associated tumorigenesis.
Author: Liu, Chao|Liu, En-Dong|Meng, Yun-Xiao|Dong, Xiao-Ming|Bi, Ya-Lan|Wu, Huan-Wen|Jin, Yan-Chao|Zhao, Ke|Li, Jian-Jie|Yu, Miao|Zhan, Yi-Qun|Chen, Hui|Ge, Chang-Hui|Yang, Xiao-Ming|Li, Chang-Yan
PMID: 29228570
Journal: Anticancer Res. 2018 Feb;38(2):811-816.
Title: The Mesenchymal-Epithelial and Epithelial-Mesenchymal Cellular Plasticity of Liver Metastases with Digestive Origin.
Author: Ceausu, Amalia Raluca|Ciolofan, Alexandru|Cimpean, Anca Maria|Magheti, Adina|Mederle, Ovidiu|Raica, Marius
PMID: 29374706
Journal: Appl Immunohistochem Mol Morphol. 2018 May 3.
Title: Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse.
Author: Buxhofer-Ausch, Veronika|Sheikh, Maidah|Ausch, Christoph|Zotter, Simone|Bauer, Heike|Mollik, Marina|Reiner, Angelika|Gleiss, Andreas|Jager, Walter|Sebesta, Christian|Kriwanek, Stephan|Thalhammer, Theresia
PMID: 29734253