Literatures

Primary Site >> Colorectal Cancer

Gene >> KRAS

1.
Journal:	Jpn J Cancer Res. 1986 Sep;77(9):901-7.
Title:	Colon carcinoma K-ras 2 oncogene of a familial polyposis coli patient.
Author:	Yuasa, Y\|Oto, M\|Sato, C\|Miyaki, M\|Iwama, T\|Tonomura, A\|Namba, M
PMID:	3021699

2.
Journal:	Int J Cancer. 1987 Sep 15;40(3):293-9.
Title:	Prognostic implications of expression of the cellular genes myc, fos, Ha-ras and Ki-ras in colon carcinoma.
Author:	Monnat, M\|Tardy, S\|Saraga, P\|Diggelmann, H\|Costa, J
PMID:	3040597

3.
Journal:	N Engl J Med. 1987 Oct 8;317(15):929-35.
Title:	Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung.
Author:	Rodenhuis, S\|van de Wetering, M L\|Mooi, W J\|Evers, S G\|van Zandwijk, N\|Bos, J L
PMID:	3041218

4.
Journal:	Oncogene. 1987;1(3):315-8.
Title:	c-K-ras mutations in human carcinomas occur preferentially in codon 12.
Author:	Yanez, L\|Groffen, J\|Valenzuela, D M
PMID:	3330777

5.
Journal:	Cancer Res. 1987 Jul 15;47(14):3763-5.
Title:	Overexpression of ras in mucus-secreting human colon carcinoma cells of low tumorigenicity.
Author:	Augenlicht, L H\|Augeron, C\|Yander, G\|Laboisse, C
PMID:	3594436

6.
Journal:	Oncogene. 1988 Dec;3(6):673-8.
Title:	A study of ras gene mutations in colonic adenomas from familial polyposis coli patients.
Author:	Farr, C J\|Marshall, C J\|Easty, D J\|Wright, N A\|Powell, S C\|Paraskeva, C
PMID:	2577869

7.
Journal:	Wien Med Wochenschr. 1988 Jun 30;138(11-12):271-3.
Title:	[Oncogene expression in colonic cancers].
Author:	Hofler, H
PMID:	3051685

8.
Journal:	Lancet. 1989 Aug 12;2(8659):353-6.
Title:	Multiple genetic alterations in distal and proximal colorectal cancer.
Author:	Delattre, O\|Olschwang, S\|Law, D J\|Melot, T\|Remvikos, Y\|Salmon, R J\|Sastre, X\|Validire, P\|Feinberg, A P\|Thomas, G
PMID:	2569552

9.
Journal:	Proc Natl Acad Sci U S A. 1989 Apr;86(7):2403-7.
Title:	Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma.
Author:	Burmer, G C\|Loeb, L A
PMID:	2648401

10.
Journal:	Cancer Res. 1989 Apr 15;49(8):2141-6.
Title:	Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing.
Author:	Burmer, G C\|Rabinovitch, P S\|Loeb, L A
PMID:	2649235

11.
Journal:	Dis Colon Rectum. 1989 Aug;32(8):659-64.
Title:	Detection of ras gene alterations and ras proteins in colorectal cancer.
Author:	Salhab, N\|Jones, D J\|Bos, J L\|Kinsella, A\|Schofield, P F
PMID:	2666051

12.
Journal:	Cancer. 1989 Aug 1;64(3):704-9.
Title:	Expression of c-myc oncogene in colorectal polyps as a biological marker for monitoring malignant potential.
Author:	Imaseki, H\|Hayashi, H\|Taira, M\|Ito, Y\|Tabata, Y\|Onoda, S\|Isono, K\|Tatibana, M
PMID:	2743265

13.
Journal:	Jpn J Med. 1990 Jul-Aug;29(4):391-6.
Title:	Rearrangement, amplification and overexpression of c-Ha Ras gene in premalignant lesion of Turcot's syndrome.
Author:	Minami, T\|Himeno, S\|Shinomura, Y\|Kariya, Y\|Tarui, S\|Sakurai, M
PMID:	1703248

14.
Journal:	Gan To Kagaku Ryoho. 1990 Jul;17(7):1266-73.
Title:	[Molecular pathological diagnosis of cancer].
Author:	Yasui, W\|Tahara, E
PMID:	1973345

15.
Journal:	Cancer. 1990 Jun 1;65(11):2576-9.
Title:	K-ras activation in colorectal tumors from patients with familial polyposis coli.
Author:	Sasaki, M\|Sugio, K\|Sasazuki, T
PMID:	2159840

16.
Journal:	Scand J Gastroenterol Suppl. 1990;175:166-76.
Title:	Lessons from the genetics of colon cancer.
Author:	Ahnen, D J
PMID:	2173130

17.
Journal:	Cancer Res. 1990 Jun 15;50(12):3627-30.
Title:	Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products.
Author:	Meltzer, S J\|Mane, S M\|Wood, P K\|Resau, J H\|Newkirk, C\|Terzakis, J A\|Korelitz, B I\|Weinstein, W M\|Needleman, S W
PMID:	2187599

18.
Journal:	Gastroenterol Clin Biol. 1990;14(4):347-51.
Title:	[A joint study of mutation of the Ki-ras oncogene and overexpression of the Tp53 oncogene in colorectal cancer].
Author:	Laurent-Puig, P\|Delattre, O\|Olschwang, S\|Remvikos, Y\|Melot, T\|Salmon, R J\|Frelat, G\|Thomas, G
PMID:	2190855

19.
Journal:	Gastroenterology. 1990 Aug;99(2):416-20.
Title:	c-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma.
Author:	Burmer, G C\|Levine, D S\|Kulander, B G\|Haggitt, R C\|Rubin, C E\|Rabinovitch, P S
PMID:	2194896

20.
Journal:	Int J Cancer. 1990 Sep 15;46(3):426-31.
Title:	K-ras mutations (codon 12) are not involved in down-regulation of MHC class-I genes in colon carcinomas.
Author:	Oliva, M R\|Cabrera, T\|Esquivias, J\|Perez-Ayala, M\|Redondo, M\|Ruiz-Cabello, F\|Garrido, F
PMID:	2203688

21.
Journal:	Cancer Res. 1990 Feb 1;50(3):480-2.
Title:	Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers.
Author:	Nagata, Y\|Abe, M\|Kobayashi, K\|Yoshida, K\|Ishibashi, T\|Naoe, T\|Nakayama, E\|Shiku, H
PMID:	2404571

22.
Journal:	Int J Cancer. 1991 Sep 9;49(2):220-3.
Title:	Association of Ki-ras mutation with differentiation and tumor-formation pathways in colorectal carcinoma.
Author:	Laurent-Puig, P\|Olschwang, S\|Delattre, O\|Validire, P\|Melot, T\|Mosseri, V\|Salmon, R J\|Thomas, G
PMID:	1652568

23.
Journal:	Genes Chromosomes Cancer. 1991 Nov;3(6):468-73.
Title:	Evidence for a common molecular pathogenesis in colorectal, gastric, and pancreatic cancer.
Author:	Neuman, W L\|Wasylyshyn, M L\|Jacoby, R\|Erroi, F\|Angriman, I\|Montag, A\|Brasitus, T\|Michelassi, F\|Westbrook, C A
PMID:	1663781

24.
Journal:	J Formos Med Assoc. 1991 Dec;90(12):1149-54.
Title:	Analysis of ras gene mutations in gastrointestinal cancers.
Author:	Shen, C\|Chang, J G\|Lee, L S\|Yang, M J\|Chen, T C\|Lin, K Y\|Lee, M D\|Chen, P H
PMID:	1686883

25.
Journal:	Environ Health Perspect. 1991 Jun;93:27-31.
Title:	Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinoma, carcinomas arising in ulcerative colitis, and pancreatic adenocarcinoma.
Author:	Burmer, G C\|Rabinovitch, P S\|Loeb, L A
PMID:	1773797

26.
Journal:	Gan To Kagaku Ryoho. 1991 Jan;18(1):14-21.
Title:	[Diagnosis of colorectal cancer from DNA level].
Author:	Shirasawa, S\|Yanagawa, Y\|Sasazuki, T
PMID:	1846282

27.
Journal:	Gan To Kagaku Ryoho. 1991 Apr;18(4):515-21.
Title:	[Cytomolecular aspects of colorectal carcinoma].
Author:	Miki, Y\|Nishisho, I\|Miyoshi, Y\|Nakamura, Y
PMID:	1849388

28.
Journal:	Br J Cancer. 1991 Jul;64(1):174-8.
Title:	c-Ki-ras gene mutations in dysplasia and carcinomas complicating ulcerative colitis.
Author:	Bell, S M\|Kelly, S A\|Hoyle, J A\|Lewis, F A\|Taylor, G R\|Thompson, H\|Dixon, M F\|Quirke, P
PMID:	1854618

29.
Journal:	Oncogene. 1991 Aug;6(8):1471-6.
Title:	Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-beta.
Author:	Manning, A M\|Williams, A C\|Game, S M\|Paraskeva, C
PMID:	1886718

30.
Journal:	Nihon Shokakibyo Gakkai Zasshi. 1991 Aug;88(8):1539-44.
Title:	[Prevalence of K-ras gene mutations in human colorectal cancers].
Author:	Hayakumo, T\|Azuma, T\|Nakajima, M\|Yasuda, K\|Cho, E\|Mukai, H\|Mizuma, Y\|Ashihara, T\|Mizuno, S\|Hirano, S
PMID:	1942608

31.
Journal:	Int J Cancer. 1991 Dec 2;49(6):875-9.
Title:	Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver.
Author:	Oudejans, J J\|Slebos, R J\|Zoetmulder, F A\|Mooi, W J\|Rodenhuis, S
PMID:	1959991

32.
Journal:	Virus Genes. 1991 Jan;5(1):75-9.
Title:	A novel point mutation at codon 146 of the K-ras gene in a human colorectal cancer identified by the polymerase chain reaction.
Author:	Orita, S\|Higashi, T\|Kawasaki, Y\|Harada, A\|Igarashi, H\|Monden, T\|Morimoto, H\|Shimano, T\|Mori, T\|Miyoshi, J
PMID:	2017878

33.
Journal:	Cancer Lett. 1991 Jun 14;58(1-2):107-13.
Title:	K-ras activation in gastric epithelial tumors in Japanese.
Author:	Miki, H\|Ohmori, M\|Perantoni, A O\|Enomoto, T
PMID:	2049776

34.
Journal:	Patol Pol. 1992;43(3):73-8.
Title:	Colorectal carcinoma as a genetic phenomenon.
Author:	Waliszewski, P
PMID:	1294935

35.
Journal:	Eur J Cancer. 1992;28(1):296-8.
Title:	Multistage carcinogenesis in paediatric and adult cancers.
Author:	Mitchell, C
PMID:	1314630

36.
Journal:	Fukuoka Igaku Zasshi. 1992 Feb;83(2):96-106.
Title:	[Genetic analysis of adenomatous polyposis coli: analysis of alterations of oncogenes and tumor suppressor genes in colorectal tumors].
Author:	Toshitani, K
PMID:	1317336

37.
Journal:	Surg Oncol. 1992 Aug;1(4):275-82.
Title:	K-ras gene mutations in adenomas and carcinomas of the colon.
Author:	Boughdady, I S\|Kinsella, A R\|Haboubi, N Y\|Schofield, P F
PMID:	1341261

38.
Journal:	Cancer. 1992 Dec 15;70(12):2772-7.
Title:	Expression of p53 protein in invasive colorectal carcinomas of different histologic types.
Author:	Hanski, C\|Bornhoeft, G\|Shimoda, T\|Hanski, M L\|Lane, D P\|Stein, H\|Riecken, E O
PMID:	1451054

39.
Journal:	Kobe J Med Sci. 1992 Jun;38(3):161-73.
Title:	Genetic changes in multi-step development of colorectal cancer.
Author:	Tokisue, M\|Yasutake, K\|Nakagawa, T\|Kasuga, M
PMID:	1453686

40.
Journal:	Acta Obstet Gynecol Scand Suppl. 1992;155:25-30.
Title:	Oncogenesis in ovarian cancer.
Author:	Borresen, A L
PMID:	1502889

41.
Journal:	Clin Exp Metastasis. 1992 Sep;10(5):351-60.
Title:	NIH3T3 transfectant containing human K-ras oncogene shows enhanced metastatic activity after in vivo tumor growth or co-culture with fibroblasts.
Author:	Takiguchi, Y\|Takahashi, Y\|Kuriyama, T\|Miyamoto, T
PMID:	1505125

42.
Journal:	Mod Pathol. 1992 Mar;5(2):131-4.
Title:	Lack of ras mutations and prediction of long-term survival in carcinoma of the colon.
Author:	Halter, S A\|Webb, L\|Rose, J
PMID:	1574489

43.
Journal:	Carcinogenesis. 1992 Jan;13(1):45-9.
Title:	K-ras oncogene mutations in rat colon tumors induced by N-methyl-N-nitrosourea.
Author:	Jacoby, R F\|Alexander, R J\|Raicht, R F\|Brasitus, T A
PMID:	1733572

44.
Journal:	Nihon Geka Gakkai Zasshi. 1993 Dec;94(12):1249-55.
Title:	[Cell kinetics of colorectal tumors with assessment by K-ras mutation and PCNA labeling index].
Author:	Tanaka, M\|Omura, K\|Ishida, F\|Watanabe, Y
PMID:	7903793

45.
Journal:	J Clin Pathol. 1993 Jul;46(7):621-3.
Title:	K-ras point mutations in routinely processed tissues: non-radioactive screening by single strand conformational polymorphism analysis.
Author:	Korn, S H\|Moerkerk, P T\|de Goeij, A F
PMID:	8157747

46.
Journal:	J Natl Cancer Inst. 1993 Dec 15;85(24):2004-7.
Title:	K-ras mutations in putative preneoplastic lesions in human colon.
Author:	Pretlow, T P\|Brasitus, T A\|Fulton, N C\|Cheyer, C\|Kaplan, E L
PMID:	8246286

47.
Journal:	Am J Clin Pathol. 1993 Dec;100(6):686-9.
Title:	Mutation analysis of K-ras oncogenes in gastroenterologic cancers by the amplified created restriction sites method.
Author:	Lin, S Y\|Chen, P H\|Wang, C K\|Liu, J D\|Siauw, C P\|Chen, Y J\|Yang, M J\|Liu, M H\|Chen, T C\|Chang, J G
PMID:	8249918

48.
Journal:	Rinsho Byori. 1993 Sep;41(9):1017-23.
Title:	[Sensitive detection of K-ras oncogene codon 12 mutations by nested PCR using mismatched primers and selective digestion of non-mutated PCR fragments with restriction enzyme].
Author:	Fukayama, N\|Sugano, K\|Kyogoku, A\|Nose, H\|Kondou, H\|Ohkura, H
PMID:	8254964

49.
Journal:	Lab Invest. 1993 Dec;69(6):674-81.
Title:	Immunohistochemical detection of RAS, JUN, FOS, and p53 oncoprotein expression in human colorectal adenomas and carcinomas.
Author:	Magrisso, I J\|Richmond, R E\|Carter, J H\|Pross, C B\|Gilfillen, R A\|Carter, H W
PMID:	8264230

50.
Journal:	Jpn J Clin Oncol. 1993 Dec;23(6):350-5.
Title:	Mutational heterogeneity among individual tumors in a case of multiple primary malignancy of the colon.
Author:	Terunuma, H\|Hayakashi, T\|Tsuneyoshi, T\|Fujita, M\|Kino, I\|Baba, S
PMID:	8283788

51.
Journal:	Hum Mutat. 1993;2(2):112-7.
Title:	Detection of K-ras mutation in sputum by mutant-allele-specific amplification (MASA).
Author:	Takeda, S\|Ichii, S\|Nakamura, Y
PMID:	8318987

52.
Journal:	Mol Carcinog. 1993;8(1):44-8.
Title:	Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis.
Author:	Kakiuchi, H\|Ushijima, T\|Ochiai, M\|Imai, K\|Ito, N\|Yachi, A\|Sugimura, T\|Nagao, M
PMID:	8352890

53.
Journal:	Hum Genet. 1993 Oct 1;92(3):244-9.
Title:	Loss of heterozygosity and K-ras gene mutations in gastric cancer.
Author:	Ranzani, G N\|Renault, B\|Pellegata, N S\|Fattorini, P\|Magni, E\|Bacci, F\|Amadori, D
PMID:	8406432

54.
Journal:	Gastroenterology. 1993 Jan;104(1):57-64.
Title:	Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer.
Author:	Bell, S M\|Scott, N\|Cross, D\|Sagar, P\|Lewis, F A\|Blair, G E\|Taylor, G R\|Dixon, M F\|Quirke, P
PMID:	8419262

55.
Journal:	Oncology. 1993;50(1):70-6.
Title:	Position specificity of Ki-ras oncogene mutations during the progression of colorectal carcinoma.
Author:	Rochlitz, C F\|Heide, I\|de Kant, E\|Bohmer, R\|Peter, F J\|Neuhaus, P\|Huhn, D\|Herrmann, R
PMID:	8421601

56.
Journal:	Science. 1993 Apr 2;260(5104):85-8.
Title:	Altered growth of human colon cancer cell lines disrupted at activated Ki-ras.
Author:	Shirasawa, S\|Furuse, M\|Yokoyama, N\|Sasazuki, T
PMID:	8465203

57.
Journal:	J Gastroenterol Hepatol. 1993 Mar-Apr;8(2):174-84.
Title:	Tumour suppressor genes and colorectal neoplasia.
Author:	Koorey, D J\|McCaughan, G W
PMID:	8471756

58.
Journal:	Science. 1993 May 7;260(5109):812-6.
Title:	Clues to the pathogenesis of familial colorectal cancer.
Author:	Aaltonen, L A\|Peltomaki, P\|Leach, F S\|Sistonen, P\|Pylkkanen, L\|Mecklin, J P\|Jarvinen, H\|Powell, S M\|Jen, J\|Hamilton, S R
PMID:	8484121

59.
Journal:	Int J Cancer. 1993 May 8;54(2):249-54.
Title:	Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia.
Author:	Urosevic, N\|Krtolica, K\|Skaro-Milic, A\|Knezevic-Usaj, S\|Dujic, A
PMID:	8486427

60.
Journal:	Br J Surg. 1993 Apr;80(4):442-4.
Title:	Expression of p53 in colorectal cancer and dysplasia complicating ulcerative colitis.
Author:	Taylor, H W\|Boyle, M\|Smith, S C\|Bustin, S\|Williams, N S
PMID:	8495305

61.
Journal:	J Natl Cancer Inst. 1993 Jul 7;85(13):1058-63.
Title:	Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas.
Author:	Shibata, D\|Schaeffer, J\|Li, Z H\|Capella, G\|Perucho, M
PMID:	8515492

62.
Journal:	Int J Oncol. 1993 Feb;2(2):123-34.
Title:	Mutations in the p53 suppressor gene do not correlate with C-k-ras oncogene mutations in colorectal-cancer.
Author:	Peinado, M\|Fernandezrenart, M\|Capella, G\|Wilson, L\|Perucho, M
PMID:	21573526

63.
Journal:	G E N. 1994 Oct-Dec;48(4):264-72.
Title:	[Etiology of colorectal cancer].
Author:	Matos Villalobos, M
PMID:	7557283

64.
Journal:	Eur J Cancer. 1994;30A(8):1113-7.
Title:	c-myc mRNA overexpression is associated with lymph node metastasis in colorectal cancer.
Author:	Sato, K\|Miyahara, M\|Saito, T\|Kobayashi, M
PMID:	7654441

65.
Journal:	Gut. 1994 Nov;35(11):1627-31.
Title:	Mutations of Ki-ras and p53 genes in colorectal cancer and their prognostic significance.
Author:	Morrin, M\|Kelly, M\|Barrett, N\|Delaney, P
PMID:	7828987

66.
Journal:	C R Acad Sci III. 1994 Oct;317(10):869-74.
Title:	[Transformation of NIH/3T3 cells and SW 480 cells displaying K-ras mutation].
Author:	Anker, P\|Lyautey, J\|Lefort, F\|Lederrey, C\|Stroun, M
PMID:	7882132

67.
Journal:	Carcinogenesis. 1994 Jul;15(7):1365-9.
Title:	Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.
Author:	Oda, Y\|Tanaka, M\|Nakanishi, I
PMID:	7913423

68.
Journal:	Oncogene. 1994 Dec;9(12):3701-6.
Title:	The capacity for growth stimulation by TGF beta 1 seen only in advanced colon cancers cannot be ascribed to mutations in APC, DCC, p53 or ras.
Author:	Huang, F\|Hsu, S\|Yan, Z\|Winawer, S\|Friedman, E
PMID:	7970729

69.
Journal:	Biochem Biophys Res Commun. 1994 Jun 15;201(2):574-80.
Title:	Ki-ras and c-myc oncogene expression measured by coamplification polymerase chain reaction.
Author:	Sugimoto, T\|Tsukamato, F\|Fujita, M\|Takai, S
PMID:	8002989

70.
Journal:	J Natl Cancer Inst. 1994 Jul 6;86(13):1007-10.
Title:	Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma.
Author:	Tobi, M\|Luo, F C\|Ronai, Z
PMID:	8007010

71.
Journal:	Cancer Res. 1994 Jul 1;54(13):3376-8.
Title:	Type and number of Ki-ras point mutations relate to stage of human colorectal cancer.
Author:	Moerkerk, P\|Arends, J W\|van Driel, M\|de Bruine, A\|de Goeij, A\|ten Kate, J
PMID:	8012953

72.
Journal:	J Natl Cancer Inst. 1994 Aug 17;86(16):1216-21.
Title:	Microsatellite instability in sporadic endometrial carcinoma.
Author:	Duggan, B D\|Felix, J C\|Muderspach, L I\|Tourgeman, D\|Zheng, J\|Shibata, D
PMID:	8040889

73.
Journal:	Gan To Kagaku Ryoho. 1994 Feb;21(3):343-50.
Title:	[Genetic alterations of human colorectal cancer].
Author:	Suzuki, T\|Ishioka, C\|Gamo, M\|Niitani, T\|Shimodaira, H\|Kanbe, M\|Yamazaki, T\|Yusa, Y\|Kanamaru, R
PMID:	8109990

74.
Journal:	Am J Pathol. 1994 Apr;144(4):767-75.
Title:	K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis.
Author:	Chaubert, P\|Benhattar, J\|Saraga, E\|Costa, J
PMID:	8160776

75.
Journal:	Cancer Res. 1994 Jun 1;54(11):2841-4.
Title:	Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas.
Author:	Minamoto, T\|Sawaguchi, K\|Mai, M\|Yamashita, N\|Sugimura, T\|Esumi, H
PMID:	8187064

76.
Journal:	Nihon Geka Gakkai Zasshi. 1994 Apr;95(4):242-7.
Title:	[Molecular oncological study on DNA ploidy, Ki-ras point mutation, and p21 expression in colorectal cancer].
Author:	Yamazaki, K\|Sato, K\|Hirata, S\|Ikeda, K\|Kubo, Y\|Matsui, H\|Ogawa, K
PMID:	8196591

77.
Journal:	Int J Oncol. 1994 Feb;4(2):391-6.
Title:	Detection of k-ras mutation in normal and malignant colonic tissues by an enriched PCR method.
Author:	Ronai, Z\|Luo, F\|Gradia, S\|Hart, W\|Butler, R
PMID:	21566936

78.
Journal:	Int J Oncol. 1994 Feb;4(2):397-401.
Title:	Detection of ki-ras mutation in nonneoplastic mucosa of Japanese patients with colorectal cancers.
Author:	Minamoto, T\|Ronai, Z\|Yamashita, N\|Ochiai, A\|Sugimura, T\|Mai, M\|Esumi, H
PMID:	21566937

79.
Journal:	Int J Oncol. 1994 Apr;4(4):993-1000.
Title:	The overexpression of the sialyl-lewis(x) moiety is an independent and a more consistent marker of colon carcinogenesis than the overexpression of C-myc and ki-ras oncogenes.
Author:	Hanski, C\|Odefey, U\|Ogorek, D\|Wang, J\|Bornhoeft, G\|Riecken, E
PMID:	21567012

80.
Journal:	Oncol Rep. 1994 May;1(3):547-9.
Title:	Activating mutations in the k-ras gene in ulcerative-colitis and crohns-disease.
Author:	Spandidos, D\|Kiaris, H\|Lioudaki, E\|Manousos, O
PMID:	21607401

81.
Journal:	Tidsskr Nor Laegeforen. 1995 Oct 30;115(26):3266-70.
Title:	[Determination of the activated proto-oncogene (Ki-ras) in feces. A new laboratory analysis for early diagnosis of colorectal cancer].
Author:	Koornstra, J J\|Rokke, O\|Halvorsen, J F\|Haug, K\|Ogreid, D
PMID:	7482456

82.
Journal:	Diagn Mol Pathol. 1995 Sep;4(3):198-202.
Title:	Adenoma-carcinoma sequence of colorectum. Prevalence of K-ras gene mutation in adenomas with increasing degree of dysplasia and aneuploidy.
Author:	Ranaldi, R\|Gioacchini, A M\|Manzin, A\|Clementi, M\|Paolucci, S\|Bearzi, I
PMID:	7493139

83.
Journal:	Cancer Res. 1995 Oct 15;55(20):4575-80.
Title:	Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.
Author:	Rak, J\|Mitsuhashi, Y\|Bayko, L\|Filmus, J\|Shirasawa, S\|Sasazuki, T\|Kerbel, R S
PMID:	7553632

84.
Journal:	Eur J Cancer. 1995 Jul-Aug;31A(7-8):1171-3.
Title:	Molecular genetics of dysplasia in ulcerative colitis.
Author:	Benhattar, J\|Saraga, E
PMID:	7577015

85.
Journal:	Anticancer Drugs. 1995 Aug;6(4):553-61.
Title:	Inhibition of colon cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA of the Ki-ras gene.
Author:	Sakakura, C\|Hagiwara, A\|Tsujimoto, H\|Ozaki, K\|Sakakibara, T\|Oyama, T\|Ogaki, M\|Imanishi, T\|Yamazaki, J\|Takahashi, T
PMID:	7579559

86.
Journal:	J Cell Physiol. 1995 Nov;165(2):239-45.
Title:	Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect.
Author:	Hsu, S\|Huang, F\|Friedman, E
PMID:	7593201

87.
Journal:	Cancer Res. 1995 Jul 15;55(14):3165-70.
Title:	Somatic mutations of the adenomatous polyposis coli gene in gastroduodenal tumors from patients with familial adenomatous polyposis.
Author:	Toyooka, M\|Konishi, M\|Kikuchi-Yanoshita, R\|Iwama, T\|Miyaki, M
PMID:	7606737

88.
Journal:	Dis Colon Rectum. 1995 Aug;38(8):853-65.
Title:	Chemotherapy-induced nuclear alterations of morphologic and genomic characteristics in a human colon cancer grafted onto nude mice.
Author:	Jannot, M C\|Yeaton, P\|Pauwels, O\|DePrez, C\|Astruc, J\|Chazottes, E\|Kruczynski, A\|Kiss, R
PMID:	7634980

89.
Journal:	Scand J Clin Lab Invest Suppl. 1995;221:116-21.
Title:	Tumour diagnosis by PCR-based detection of tumour cells.
Author:	Nollau, P\|Jung, R\|Neumaier, M\|Wagener, C
PMID:	7652485

90.
Journal:	J Clin Gastroenterol. 1995 Jun;20(4):272-6.
Title:	Using biopsy materials to detect mutations in gastrointestinal tumors.
Author:	Hosoi, H\|Hirosawa, S\|Yamamoto, K\|Ohkusa, T\|Aoki, N
PMID:	7665812

91.
Journal:	J Pathol. 1995 Jul;176(3):249-58.
Title:	The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence does not occur between gastric adenoma and adenocarcinoma.
Author:	Maesawa, C\|Tamura, G\|Suzuki, Y\|Ogasawara, S\|Sakata, K\|Kashiwaba, M\|Satodate, R
PMID:	7674088

92.
Journal:	Oncogene. 1995 Apr 6;10(7):1413-6.
Title:	K-ras gene mutations in early colorectal cancer ... flat elevated vs polyp-forming cancer....
Author:	Hasegawa, H\|Ueda, M\|Watanabe, M\|Teramoto, T\|Mukai, M\|Kitajima, M
PMID:	7731692

93.
Journal:	Carcinogenesis. 1995 May;16(5):1121-6.
Title:	Overexpression of protein kinase C beta 1 in the SW480 colon cancer cell line causes growth suppression.
Author:	Goldstein, D R\|Cacace, A M\|Weinstein, I B
PMID:	7767974

94.
Journal:	J Gastroenterol Hepatol. 1995 Mar-Apr;10(2):119-24.
Title:	Ras oncogene and p53 gene hotspot mutations in colorectal cancers.
Author:	Lin, S Y\|Chen, P H\|Yang, M J\|Chen, T C\|Chang, C P\|Chang, J G
PMID:	7787154

95.
Journal:	Arch Surg. 1995 Jan;130(1):9-14.
Title:	K-ras status does not predict successful hepatic resection of colorectal cancer metastasis.
Author:	Kastrinakis, W V\|Ramchurren, N\|Maggard, M\|Steele, G Jr\|Summerhayes, I C
PMID:	7802584

96.
Journal:	Eur J Surg Oncol. 1995 Feb;21(1):96-100.
Title:	The genetic basis of colorectal cancer--clinical implications.
Author:	Tsiotou, A G\|Krespis, E N\|Sakorafas, G H\|Krespi, A E
PMID:	7851569

97.
Journal:	Gut. 1995 Jan;36(1):81-6.
Title:	Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.
Author:	Smith-Ravin, J\|England, J\|Talbot, I C\|Bodmer, W
PMID:	7890240

98.
Journal:	J Clin Lab Anal. 1995;9(5):297-301.
Title:	Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells.
Author:	Yamamoto, H\|Itoh, F\|Senota, A\|Adachi, Y\|Yoshimoto, M\|Endoh, T\|Hinoda, Y\|Yachi, A\|Imai, K
PMID:	8531010

99.
Journal:	J Gastroenterol. 1995 Nov;30 Suppl 8:30-2.
Title:	Detection of c-ras gene mutation and expression of p21 protein in dysplasias and carcinomas complicating ulcerative colitis.
Author:	Tsuda, T\|Mochizuki, M\|Wakasa, H
PMID:	8563883

100.
Journal:	Swiss Surg. 1995;(6):304-6.
Title:	[Prognostic value of K-ras gene mutation in colorectal cancer].
Author:	Cerottini, J P\|Givel, J C\|Benhattar, J
PMID:	8581817

101.
Journal:	Semin Surg Oncol. 1995 Nov-Dec;11(6):399-405.
Title:	Molecular biology of colon polyps and colon cancer.
Author:	Allen, J I
PMID:	8607008

102.
Journal:	Mol Med. 1995 Nov;1(7):789-94.
Title:	Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease.
Author:	Hardingham, J E\|Kotasek, D\|Sage, R E\|Eaton, M C\|Pascoe, V H\|Dobrovic, A
PMID:	8612201

103.
Journal:	Southeast Asian J Trop Med Public Health. 1995;26 Suppl 1:190-6.
Title:	Multistep carcinogenesis in colorectal cancers.
Author:	Takami, K\|Yana, I\|Kurahashi, H\|Nishisho, I
PMID:	8629105

104.
Journal:	Diagn Mol Pathol. 1995 Dec;4(4):261-5.
Title:	Clonal analysis of colorectal tumors using K-ras and p53 gene mutations as markers.
Author:	Dix, B R\|Robbins, P D\|Spagnolo, D V\|Padovan, G L\|House, A K\|Iacopetta, B J
PMID:	8634782

105.
Journal:	Cancer Surv. 1995;25:335-55.
Title:	Emergent issues in the genetics of intestinal neoplasia.
Author:	Dove, W F\|Gould, K A\|Luongo, C\|Moser, A R\|Shoemaker, A R
PMID:	8718526

106.
Journal:	Cancer Detect Prev. 1995;19(6):512-7.
Title:	Sampling method as a key factor in identifying K-ras oncogene mutations in preneoplastic colorectal lesions.
Author:	Ronai, Z\|Minamoto, T\|Butler, R\|Tobi, M\|Luo, F Q\|Zang, E\|Esumi, H\|Sugimura, T
PMID:	8925520

107.
Journal:	Clin Cancer Res. 1995 Apr;1(4):441-5.
Title:	Mutant K-ras oncogenes in colon cancers Do not predict Patient's chemotherapy response or survival
Author:	Markowitz\|Hines\|Lutterbaugh\|Myeroff\|Mackay\|Gordon\|Rustum\|Luna\|Kleinerman
PMID:	9816002

108.
Journal:	Clin Mol Pathol. 1995 Oct;48(5):M273-7.
Title:	A rapid PCR ELISA for the detection of activated K-ras in colorectal cancer.
Author:	Ward, R L\|Santiago, F\|Hawkins, N J\|Coomber, D\|O'connor, T\|Todd, A V
PMID:	16696021

109.
Journal:	Int J Oncol. 1995 Jan;6(1):191-5.
Title:	K-ras mutation in colorectal carcinomas from singapore.
Author:	Phang, T\|Shi, C\|Wee, A\|Ngoi, S\|Li, B\|Lee, H\|Ong, C
PMID:	21556523

110.
Journal:	Int J Oncol. 1995 Apr;6(4):767-72.
Title:	Alterations of p53 and k-ras genes in human colorectal-cancer with ulcerative-colitis.
Author:	Tsuruta, H\|Urano, T\|Makiyama, K\|Abe, K\|Itsuno, M\|Hara, K\|Shiku, H
PMID:	21556601

111.
Journal:	Am J Surg. 1996 Jan;171(1):10-5.
Title:	Contributions of molecular genetics to the clinical management of colorectal cancer.
Author:	Sterm, H S
PMID:	8554121

112.
Journal:	Dig Dis Sci. 1996 Jan;41(1):115-8.
Title:	Frequent K-ras mutations in small bowel adenocarcinomas.
Author:	Sutter, T\|Arber, N\|Moss, S F\|Findling, R I\|Neugut, A I\|Weinstein, I B\|Holt, P R
PMID:	8565742

113.
Journal:	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1082-6.
Title:	Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer.
Author:	Moen, C J\|Groot, P C\|Hart, A A\|Snoek, M\|Demant, P
PMID:	8577718

114.
Journal:	Cancer. 1996 Apr 15;77(8 Suppl):1729-35.
Title:	Detection of DCC and Ki-ras gene alterations in colorectal carcinoma tissue as prognostic markers for liver metastatic recurrence.
Author:	Kato, M\|Ito, Y\|Kobayashi, S\|Isono, K
PMID:	8608570

115.
Journal:	Int J Cancer. 1996 May 3;66(3):332-6.
Title:	Detection of K-ras mutations in stools of patients with colorectal cancer by mutant-enriched PCR.
Author:	Nollau, P\|Moser, C\|Weinland, G\|Wagener, C
PMID:	8621253

116.
Journal:	Am J Pathol. 1996 May;148(5):1671-8.
Title:	Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.
Author:	Caduff, R F\|Johnston, C M\|Svoboda-Newman, S M\|Poy, E L\|Merajver, S D\|Frank, T S
PMID:	8623934

117.
Journal:	Am J Gastroenterol. 1996 Mar;91(3):587-91.
Title:	K-ras mutation in a tubular adenoma originating at an ileostomy in a familial adenomatous polyposis patient.
Author:	Herring, J A\|Hall, C C\|Johnson, J A\|Poole, G V\|Subramony, C\|Suvarna-Gurram, V\|Hall, T J
PMID:	8633516

118.
Journal:	Mol Carcinog. 1996 May;16(1):12-9.
Title:	Frequency of Ki-ras mutations and DNA alkylation in colorectal tissue from individuals living in Manchester.
Author:	Jackson, P E\|Hall, C N\|Badawi, A F\|O'Connor, P J\|Cooper, D P\|Povey, A C
PMID:	8634090

119.
Journal:	Lab Invest. 1996 May;74(5):933-40.
Title:	A novel method for gene analysis of colorectal carcinomas using a crypt isolation technique.
Author:	Habano, W\|Sugai, T\|Nakamura, S\|Yoshida, T
PMID:	8642788

120.
Journal:	Ann Surg Oncol. 1996 Mar;3(2):136-43.
Title:	Synchronous colon carcinomas: molecular-genetic evidence for multicentricity.
Author:	Koness, R J\|King, T C\|Schechter, S\|McLean, S F\|Lodowsky, C\|Wanebo, H J
PMID:	8646513

121.
Journal:	Oncogene. 1996 May 2;12(9):1903-8.
Title:	Increased expression of cyclin D1 and the Rb tumor suppressor gene in c-K-ras transformed rat enterocytes.
Author:	Arber, N\|Sutter, T\|Miyake, M\|Kahn, S M\|Venkatraj, V S\|Sobrino, A\|Warburton, D\|Holt, P R\|Weinstein, I B
PMID:	8649851

122.
Journal:	Int J Cancer. 1996 Jun 21;69(3):241-5.
Title:	A detailed analysis of K-ras point mutations in relation to tumor progression and survival in colorectal cancer patients.
Author:	Span, M\|Moerkerk, P T\|De Goeij, A F\|Arends, J W
PMID:	8682594

123.
Journal:	Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6665-70.
Title:	Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells.
Author:	Plattner, R\|Anderson, M J\|Sato, K Y\|Fasching, C L\|Der, C J\|Stanbridge, E J
PMID:	8692875

124.
Journal:	Int J Cancer. 1996 Aug 7;67(4):539-46.
Title:	Maintenance of growth factor signaling through Ras in human colon carcinoma cells containing K-ras mutations.
Author:	Buard, A\|Zipfel, P A\|Frey, R S\|Mulder, K M
PMID:	8759614

125.
Journal:	J Clin Pathol. 1996 Jun;49(6):460-4.
Title:	Clinical significance of K-ras oncogene activation in ampullary neoplasms.
Author:	Chung, C H\|Wilentz, R E\|Polak, M M\|Ramsoekh, T B\|Noorduyn, L A\|Gouma, D J\|Huibregtse, K\|Offerhaus, G J\|Slebos, R J
PMID:	8763258

126.
Journal:	Tohoku J Exp Med. 1996 Apr;178(4):437-45.
Title:	Double cancer in a 74-year-old woman: a case report with genetic findings.
Author:	Katada, F\|Murakami, K\|Uzuki, M\|Horii, A
PMID:	8804161

127.
Journal:	Cancer Res. 1996 Oct 1;56(19):4307-10.
Title:	Inhibition of apoptosis in colon tumors induced in the rat by 2-amino-3-methylimidazo[4,5-f]quinoline.
Author:	Hayashi, R\|Luk, H\|Horio, D\|Dashwood, R
PMID:	8813112

128.
Journal:	Gene Ther. 1996 Jul;3(7):635-43.
Title:	Anti-tumor immunity is involved in the thymidine kinase-mediated killing of tumors induced by activated Ki-ras(G12V).
Author:	Pavlovic, J\|Nawrath, M\|Tu, R\|Heinicke, T\|Moelling, K
PMID:	8818652

129.
Journal:	Cancer Lett. 1996 Aug 23;106(1):139-44.
Title:	Detection of rare circulating human colon tumor cells in a nude mouse xenograft model.
Author:	Pages, J C\|Sordat, B\|Bautista, D\|Costa, J\|Benhattar, J
PMID:	8827058

130.
Journal:	Nihon Rinsho. 1996 Apr;54(4):906-10.
Title:	[Recent progress of molecular oncology and its contribution to clinical gastroenterology].
Author:	Imai, K\|Hinoda, Y
PMID:	8920648

131.
Journal:	Gastroenterol Clin North Am. 1996 Dec;25(4):737-54.
Title:	The cellular and molecular pathogenesis of colorectal cancer.
Author:	Carethers, J M
PMID:	8960890

132.
Journal:	Cancer Res. 1996 Dec 15;56(24):5713-9.
Title:	Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice.
Author:	Reyes, G\|Villanueva, A\|Garcia, C\|Sancho, F J\|Piulats, J\|Lluis, F\|Capella, G
PMID:	8971180

133.
Journal:	J Pathol. 1996 Dec;180(4):357-63.
Title:	Ki-ras mutations in adenomas: a characteristic of cancer-bearing colorectal mucosa.
Author:	Morris, R G\|Curtis, L J\|Romanowski, P\|Hardcastle, J D\|Jenkins, D A\|Robinson, M\|Wyllie, A H\|Bird, C C
PMID:	9014854

134.
Journal:	Anticancer Res. 1996 Nov-Dec;16(6B):3839-44.
Title:	K-ras gene mutation is a useful predictor of the survival of early stage colorectal cancers.
Author:	Lee, J C\|Wang, S T\|Lai, M D\|Lin, Y J\|Yang, H B
PMID:	9042267

135.
Journal:	Mol Diagn. 1996 Jun;1(1):5-28.
Title:	Prediction of Biologic Aggressiveness in Colorectal Cancer by p53/K-ras-2 Topographic Genotyping.
Author:	Finkelstein\|Przygodzki\|Pricolo\|Sakallah\|Swalsky\|Bakker\|Lanning\|Bland\|Cooper
PMID:	10330194

136.
Journal:	Cancer Biother Radiopharm. 1996 Dec;11(6):373-83.
Title:	Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer.
Author:	Contasta, I\|Pellegrini, P\|Berghella, A M\|Del Beato, T\|Canossi, A\|Di Rocco, M\|Adorno, D\|Casciani, C U
PMID:	10851498

137.
Journal:	Int J Oncol. 1996 Aug;9(2):327-35.
Title:	Genetics of colorectal cancer (Review).
Author:	Peddanna, N\|Mendis, R\|Holt, S\|Verma, R
PMID:	21541519

138.
Journal:	Int J Oncol. 1996 Dec;9(6):1301-6.
Title:	Mutation in the K-ras gene at codon 12 does not correlate with disease progression in colorectal carcinoma patients treated with 5-FU/folinic acid biomodulated chemotherapy.
Author:	Pickard, M\|Sherrington, P\|Brett, M\|Green, B\|Howelevans, A\|Smith, D\|Poston, G\|Kinsella, A
PMID:	21541641

139.
Journal:	Cancer Epidemiol Biomarkers Prev. 1997 Jan;6(1):57-61.
Title:	Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer.
Author:	Bautista, D\|Obrador, A\|Moreno, V\|Cabeza, E\|Canet, R\|Benito, E\|Bosch, X\|Costa, J
PMID:	8993798

140.
Journal:	Scand J Gastroenterol. 1997 Jan;32(1):62-9.
Title:	K-ras mutations and prognosis in large-bowel carcinomas.
Author:	Andersen, S N\|Lovig, T\|Breivik, J\|Lund, E\|Gaudernack, G\|Meling, G I\|Rognum, T O
PMID:	9018769

141.
Journal:	Int J Cancer. 1997 Feb 20;74(1):94-6.
Title:	K-ras and p53 mutations in hereditary non-polyposis colorectal cancers.
Author:	Losi, L\|Ponz de Leon, M\|Jiricny, J\|Di Gregorio, C\|Benatti, P\|Percesepe, A\|Fante, R\|Roncucci, L\|Pedroni, M\|Benhattar, J
PMID:	9036876

142.
Journal:	Cancer. 1997 Mar 15;79(6):1106-13.
Title:	Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis.
Author:	Ward, R L\|Todd, A V\|Santiago, F\|O'Connor, T\|Hawkins, N J
PMID:	9070487

143.
Journal:	Biochem Biophys Res Commun. 1997 Feb 24;231(3):705-11.
Title:	Overexpression of SAP-1, a transmembrane-type protein tyrosine phosphatase, in human colorectal cancers.
Author:	Seo, Y\|Matozaki, T\|Tsuda, M\|Hayashi, Y\|Itoh, H\|Kasuga, M
PMID:	9070877

144.
Journal:	Dis Colon Rectum. 1997 Feb;40(2):161-7.
Title:	Ki-ras point mutation in different types of colorectal carcinomas in early stages.
Author:	Kojima, M\|Konishi, F\|Tsukamoto, T\|Yamashita, K\|Kanazawa, K
PMID:	9075750

145.
Journal:	Am J Pathol. 1997 May;150(5):1815-25.
Title:	Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics.
Author:	Ruschoff, J\|Dietmaier, W\|Luttges, J\|Seitz, G\|Bocker, T\|Zirngibl, H\|Schlegel, J\|Schackert, H K\|Jauch, K W\|Hofstaedter, F
PMID:	9137104

146.
Journal:	Aust N Z J Surg. 1997 May;67(5):233-8.
Title:	Frequency and clinico-pathological associations of ras mutations in colorectal cancer in the Victorian population.
Author:	Thomas, R J\|Liu, Y S\|St Clair, F\|Norris, P M\|Valentine, R\|Phillips, W A
PMID:	9152150

147.
Journal:	Aust N Z J Surg. 1997 May;67(5):239-44.
Title:	K-ras mutation and loss of heterozygosity of chromosome 17p and survival in colorectal cancer.
Author:	Fung, C\|Bragg, T\|Newland, R\|Dent, O\|Nicholson, G\|Bokey, L\|Chapuis, P
PMID:	9152151

148.
Journal:	Anal Biochem. 1997 May 1;247(2):394-403.
Title:	Detection of infrequent and multiple K-ras mutations in human tumors and tumor-adjacent tissues.
Author:	Keohavong, P\|Zhu, D\|Whiteside, T L\|Swalsky, P\|Bakker, A\|Elder, E M\|Siegfried, J M\|Srivastava, S\|Finkelstein, S D
PMID:	9177704

149.
Journal:	Cancer Res. 1997 Jun 15;57(12):2485-92.
Title:	K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients.
Author:	Zhu, D\|Keohavong, P\|Finkelstein, S D\|Swalsky, P\|Bakker, A\|Weissfeld, J\|Srivastava, S\|Whiteside, T L
PMID:	9192830

150.
Journal:	Mol Carcinog. 1997 Jun;19(2):137-44.
Title:	Assessment of mutations in Ki-ras and p53 in colon cancers from azoxymethane- and dimethylhydrazine-treated rats.
Author:	Erdman, S H\|Wu, H D\|Hixson, L J\|Ahnen, D J\|Gerner, E W
PMID:	9210960

151.
Journal:	Gan To Kagaku Ryoho. 1997 Jul;24 Suppl 2:332-6.
Title:	[Findings of genetic changes in small intestinal carcinomas].
Author:	Hirai, A\|Hibi, K\|Nakamura, H\|Fujikake, Y\|Matsui, T\|Kasai, Y\|Akiyama, S\|Ito, K\|Takagi, H
PMID:	9263525

152.
Journal:	J Immunol Methods. 1997 Aug 7;206(1-2):11-9.
Title:	Detection of colorectal cancer K-ras mutations using a simplified oligonucleotide ligation assay.
Author:	Rothschild, C B\|Brewer, C S\|Loggie, B\|Beard, G A\|Triscott, M X
PMID:	9328563

153.
Journal:	Am J Clin Oncol. 1997 Oct;20(5):527-9.
Title:	Irinotecan hydrochloride (CPT-11) resistance identified by K-ras mutation in patients with progressive colon cancer after treatment with 5-fluorouracil (5-FU).
Author:	Nemunaitis, J\|Cox, J\|Meyer, W\|Courtney, A\|Mues, G
PMID:	9345343

154.
Journal:	J Biol Chem. 1997 Oct 31;272(44):27902-7.
Title:	Oncogenic c-Ki-ras but not oncogenic c-Ha-ras up-regulates CEA expression and disrupts basolateral polarity in colon epithelial cells.
Author:	Yan, Z\|Deng, X\|Chen, M\|Xu, Y\|Ahram, M\|Sloane, B F\|Friedman, E
PMID:	9346938

155.
Journal:	Surgery. 1997 Oct;122(4):765-70.
Title:	A newly identified pattern of K-ras mutations at codons 12 and 13 is associated with long-term survival in colorectal cancer.
Author:	Senagore, A J\|Biener, J T
PMID:	9347854

156.
Journal:	Gastroenterology. 1997 Nov;113(5):1589-98.
Title:	In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia.
Author:	Licato, L L\|Keku, T O\|Wurzelmann, J I\|Murray, S C\|Woosley, J T\|Sandler, R S\|Brenner, D A
PMID:	9352861

157.
Journal:	Cancer Res. 1997 Nov 1;57(21):4714-7.
Title:	Activated Ki-ras enhances sensitivity of ceramide-induced apoptosis without c-Jun NH2-terminal kinase/stress-activated protein kinase or extracellular signal-regulated kinase activation in human colon cancer cells.
Author:	Ohmori, M\|Shirasawa, S\|Furuse, M\|Okumura, K\|Sasazuki, T
PMID:	9354428

158.
Journal:	Br J Cancer. 1997;76(8):1001-10.
Title:	Manumycin and gliotoxin derivative KT7595 block Ras farnesylation and cell growth but do not disturb lamin farnesylation and localization in human tumour cells.
Author:	Nagase, T\|Kawata, S\|Tamura, S\|Matsuda, Y\|Inui, Y\|Yamasaki, E\|Ishiguro, H\|Ito, T\|Miyagawa, J\|Mitsui, H\|Yamamoto, K\|Kinoshita, M\|Matsuzawa, Y
PMID:	9376258

159.
Journal:	J Biol Chem. 1997 Dec 5;272(49):30928-36.
Title:	Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells.
Author:	Yan, Z\|Chen, M\|Perucho, M\|Friedman, E
PMID:	9388239

160.
Journal:	Scand J Clin Lab Invest. 1997 Nov;57(7):601-4.
Title:	Detection of tumour DNA in serum of colorectal cancer patients.
Author:	de Kok, J B\|van Solinge, W W\|Ruers, T J\|Roelofs, R W\|van Muijen, G N\|Willems, J L\|Swinkels, D W
PMID:	9397491

161.
Journal:	Br J Cancer. 1997;76(12):1610-6.
Title:	Colorectal carcinoma in Hong Kong: epidemiology and genetic mutations.
Author:	Yuen, S T\|Chung, L P\|Leung, S Y\|Luk, I S\|Chan, S Y\|Ho, J C\|Ho, J W\|Wyllie, A H
PMID:	9413950

162.
Journal:	Mol Carcinog. 1997 Dec;20(4):389-93.
Title:	No involvement of APC gene mutations in ulcerative colitis-associated rat colon carcinogenesis induced by 1-hydroxyanthraquinone and methylazoxymethanol acetate.
Author:	Suzui, M\|Ushijima, T\|Yoshimi, N\|Nakagama, H\|Hara, A\|Sugimura, T\|Nagao, M\|Mori, H
PMID:	9433483

163.
Journal:	Wiad Lek. 1997;50 Suppl 1 Pt 1:76-81.
Title:	[P21-ras protein in tumors of the large intestine].
Author:	Pawlowska-Wakowicz, B\|Paluszkiewicz, P\|Karski, J\|Wojcierowski, J
PMID:	9446408

164.
Journal:	Eur J Cancer. 1997 Nov;33(13):2265-72.
Title:	Ki-ras oncogene and p53 tumour suppressor gene mutations in colorectal carcinomas from the European Saar-Luxembourg region are less frequent than predicted by the classic adenoma-carcinoma sequence model.
Author:	Pauly, M\|Schmitz, M\|Kayser, I\|Tureci, O\|Lagoda, P\|Seitz, G\|Dicato, M
PMID:	9470817

165.
Journal:	Verh Dtsch Ges Pathol. 1997;81:219-27.
Title:	Molecular analysis in endometrial cancer.
Author:	Caduff, R F\|Svoboda-Neumann, S M\|Johnston, C M\|Bartos, R E\|Frank, T S
PMID:	9474873

166.
Journal:	Cell Immunol. 1997 Dec 15;182(2):137-51.
Title:	Generation of stable CD4+ and CD8+ T cell lines from patients immunized with ras oncogene-derived peptides reflecting codon 12 mutations.
Author:	Abrams, S I\|Khleif, S N\|Bergmann-Leitner, E S\|Kantor, J A\|Chung, Y\|Hamilton, J M\|Schlom, J
PMID:	9514698

167.
Journal:	Clin Cancer Res. 1997 Aug;3(8):1413-7.
Title:	Combined analysis of microsatellite instability and K-ras mutation increases detection incidence of normal samples from colorectal cancer patients.
Author:	Minamoto, T\|Esumi, H\|Ochiai, A\|Belitsky, G\|Mai, M\|Sugimura, T\|Ronai, Z
PMID:	9815826

168.
Journal:	Cancer Biother Radiopharm. 1997 Dec;12(6):385-93.
Title:	Immunological implications of alterations in the c-Ki-ras and p53 genes in the stepwise progression of colorectal cancer: indications for the improvement of prognosis, biotherapy treatment and tumor biology understanding
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PMID:	10851492

169.
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Title:	Suppression of serum-induced c-jun expression by activated Ki-ras in human colon cancer cells.
Author:	Furuse, M\|Shirasawa, S\|Okumura, K\|Ohmori, M\|Sasazuki, T
PMID:	12503187

170.
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Title:	ras and myc analysis in primary and metastatic colorectal carcinomas.
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171.
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Title:	MHC class I bound peptides of a colon carcinoma cell line, a Ki-ras gene-targeted progeny cell line and a B cell line.
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172.
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Title:	Molecular pathogenesis of sporadic duodenal cancer.
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173.
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Title:	Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study.
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174.
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Title:	Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells.
Author:	Okada, F\|Rak, J W\|Croix, B S\|Lieubeau, B\|Kaya, M\|Roncari, L\|Shirasawa, S\|Sasazuki, T\|Kerbel, R S
PMID:	9520413

175.
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Title:	Comparative analysis of histology, DNA content, p53 and Ki-ras mutations in colectomy specimens with long-standing ulcerative colitis.
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176.
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Title:	Molecular detection of genetic alterations in the serum of colorectal cancer patients.
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177.
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178.
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Title:	Immunoperoxidase staining for cytokeratins 8 and 18 is very sensitive for detection of occult node metastasis of colorectal cancer: a comparison with genetic analysis of K-ras.
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179.
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Title:	The detection of K-ras mutations in colorectal cancer using the amplification-refractory mutation system.
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180.
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181.
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Title:	Role of K-ras mutations in colorectal carcinoma.
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182.
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Title:	Genetic alterations in a patient with Turcot's syndrome.
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183.
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184.
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Title:	Detection of K-ras point mutations in the supernatants of peritoneal and pleural effusions for diagnosis complementary to cytologic examination.
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PMID:	9620027

185.
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Title:	Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+.
Author:	Goggins, M\|Offerhaus, G J\|Hilgers, W\|Griffin, C A\|Shekher, M\|Tang, D\|Sohn, T A\|Yeo, C J\|Kern, S E\|Hruban, R H
PMID:	9626054

186.
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Title:	Primary cancer of the small intestine and mutational analysis of the K-ras and p53 genes.
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187.
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188.
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PMID:	9695076

189.
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190.
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PMID:	9703874

191.
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Title:	Restriction endonuclease-mediated selective polymerase chain reaction: a novel assay for the detection of K-ras mutations in clinical samples.
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PMID:	9708798

192.
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Title:	Ki-ras mutations and prognosis in colorectal cancer.
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193.
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Title:	Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality.
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PMID:	9713338

194.
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Title:	Identification of a human CD8+ T lymphocyte neo-epitope created by a ras codon 12 mutation which is restricted by the HLA-A2 allele.
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PMID:	9732698

195.
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Title:	Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences.
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196.
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PMID:	9778456

197.
Journal:	Teratog Carcinog Mutagen. 1998;18(4):183-97.
Title:	Long-term analysis of colonic aberrant crypt formation after treatment of Sprague-Dawley rats with azoxymethane.
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PMID:	9804274

198.
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Title:	Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.
Author:	Liu, M\|Bryant, M S\|Chen, J\|Lee, S\|Yaremko, B\|Lipari, P\|Malkowski, M\|Ferrari, E\|Nielsen, L\|Prioli, N\|Dell, J\|Sinha, D\|Syed, J\|Korfmacher, W A\|Nomeir, A A\|Lin, C C\|Wang, L\|Taveras, A G\|Doll, R J\|Njoroge, F G\|Mallams, A K\|Remiszewski, S\|Catino, J J\|Girijaval
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199.
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Title:	[Analysis of genetic disorders of cancer of the rectum: differences in relation to cancer of the colon].
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PMID:	9823556

200.
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Title:	Inhibition of apoptosis after thymineless stress is conferred by oncogenic K-Ras in colon carcinoma cells.
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PMID:	9829751

201.
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Title:	Endogenous TNF inducibility and prognosis of colorectal cancer.
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PMID:	9891459

202.
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Title:	Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients.
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PMID:	10025877

203.
Journal:	Eur J Histochem. 1998;42 Spec No:67-76.
Title:	Ki-ras and p53 gene mutations in pancreatic ductal carcinoma: a relationship with tumor phenotype and survival.
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PMID:	10076772

204.
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Title:	Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice.
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205.
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PMID:	9926917

206.
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Title:	Symptomatic colonic polyps in childhood: not so benign.
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PMID:	9932851

207.
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Title:	Molecular characteristics of poorly differentiated adenocarcinoma and signet-ring-cell carcinoma of colorectum.
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PMID:	9988229

208.
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Title:	L-myc genotypes in Hong Kong Chinese colorectal carcinoma patients.
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PMID:	10023018

209.
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PMID:	10067361

210.
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Title:	p53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer.
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PMID:	10334521

211.
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Title:	Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
Author:	Okumura, K\|Shirasawa, S\|Nishioka, M\|Sasazuki, T
PMID:	10344756

212.
Journal:	Hepatogastroenterology. 1999 Mar-Apr;46(26):830-7.
Title:	Reappraisal of K-ras and p53 gene mutations in the recurrence of Dukes' B2 rectal cancer after curative resection.
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PMID:	10370622

213.
Journal:	Hepatogastroenterology. 1999 Mar-Apr;46(26):883-90.
Title:	Clinicopathologic and carcinogenetic appraisal of DNA replication error in sporadic T3N0M0 stage colorectal cancer after curative resection.
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PMID:	10370632

214.
Journal:	Cancer. 1999 Jul 1;86(1):31-6.
Title:	K-ras mutation and loss of heterozygosity of the adenomatous polyposis coli gene in patients with colorectal adenomas with in situ carcinoma.
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PMID:	10391560

215.
Journal:	J Pathol. 1999 Mar;187(4):433-8.
Title:	Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.
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PMID:	10398103

216.
Journal:	Br J Cancer. 1999 Jan;79(1):168-71.
Title:	Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer.
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PMID:	10408710

217.
Journal:	Nihon Shokakibyo Gakkai Zasshi. 1999 Jul;96(7):809-16.
Title:	[Establishment of alpha-fetoprotein producing human rectal cancer cell line (RKK-YK) and its features].
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PMID:	10434556

218.
Journal:	Oncology. 1999;57(2):149-56.
Title:	Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival.
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PMID:	10461063

219.
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PMID:	10461447

220.
Journal:	Br J Cancer. 1999 Aug;80(12):1884-91.
Title:	Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis.
Author:	Allgayer, H\|Wang, H\|Shirasawa, S\|Sasazuki, T\|Boyd, D
PMID:	10471035

221.
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Title:	c-Ki-ras mutations in colorectal adenocarcinomas from a country with a rapidly changing colorectal cancer incidence.
Author:	Tang, W Y\|Elnatan, J\|Lee, Y S\|Goh, H S\|Smith, D R
PMID:	10496348

222.
Journal:	Genes Chromosomes Cancer. 1999 Nov;26(3):247-52.
Title:	Colorectal cancer with and without microsatellite instability involves different genes.
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PMID:	10502323

223.
Journal:	Oncol Rep. 1999 Nov-Dec;6(6):1417-20.
Title:	Cell cycle variations in azoxymethane-induced rat colorectal carcinogenesis studied by flow cytometry.
Author:	Caderni, G\|Dolara, P\|Fazi, M\|Luceri, C\|Geido, E\|Rapallo, A\|Di Vinci, A\|Giaretti, W
PMID:	10523722

224.
Journal:	Cancer Res. 1999 Oct 15;59(20):5169-75.
Title:	Sensitive detection of K-ras mutations augments diagnosis of colorectal cancer metastases in the liver.
Author:	Schimanski, C C\|Linnemann, U\|Berger, M R
PMID:	10537293

225.
Journal:	Cancer Res. 1999 Oct 15;59(20):5181-5.
Title:	Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas.
Author:	Martinez, M E\|Maltzman, T\|Marshall, J R\|Einspahr, J\|Reid, M E\|Sampliner, R\|Ahnen, D J\|Hamilton, S R\|Alberts, D S
PMID:	10537295

226.
Journal:	Cytogenet Cell Genet. 1999;86(2):112-7.
Title:	Molecular pathology of colorectal cancer.
Author:	Bosman, F T
PMID:	10545700

227.
Journal:	Scand J Gastroenterol. 1999 Nov;34(11):1162-7.
Title:	A case of adenocarcinoma of the small intestine in a Japanese patient with Crohn disease: a report with immunohistochemical and oncogenic analyses.
Author:	Uesugi, H\|Mitomi, H\|Sada, M\|Takahashi, H\|Kobayashi, K\|Igarashi, M\|Katsumata, T\|Ihara, A\|Ohtani, Y\|Ikeda, S\|Okayasu, I
PMID:	10582770

228.
Journal:	Rinsho Byori. 1999 Nov;47(11):1059-63.
Title:	[Detection of K-ras mutations in colon cancer by PHA-PHFA (preferential homoduplex formation assay)].
Author:	Funato, T\|Zeng, Z\|Satoh, J\|Fujiwara, J\|Kaku, M\|Sasaki, T
PMID:	10590684

229.
Journal:	Jpn J Cancer Res. 1999 Oct;90(10):1081-7.
Title:	Genetic alterations in ulcerative colitis-associated neoplasia focusing on APC, K-ras gene and microsatellite instability.
Author:	Umetani, N\|Sasaki, S\|Watanabe, T\|Shinozaki, M\|Matsuda, K\|Ishigami, H\|Ueda, E\|Muto, T
PMID:	10595736

230.
Journal:	Eur J Hum Genet. 1999 Dec;7(8):928-32.
Title:	Multiple APC mutations in sporadic flat colorectal adenomas.
Author:	van Wyk, R\|Slezak, P\|Kotze, M J\|Jaramillo, E\|Koizumi, K\|Grobbelaar, J J
PMID:	10602369

231.
Journal:	Med Secoli. 1999;11(1):85-105.
Title:	Renaissance mummies in Italy.
Author:	Fornaciari, G
PMID:	11624203

232.
Journal:	Genes Chromosomes Cancer. 2000 Feb;27(2):202-8.
Title:	Somatic mutations of the APC, KRAS, and TP53 genes in nonpolypoid colorectal adenomas.
Author:	van Wyk, R\|Slezak, P\|Hayes, V M\|Buys, C H\|Kotze, M J\|de Jong, G\|Rubio, C\|Dolk, A\|Jaramillo, E\|Koizumi, K\|Grobbelaar, J J
PMID:	10612810

233.
Journal:	Gut. 2000 Feb;46(2):200-4.
Title:	Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer.
Author:	Curran, B\|Lenehan, K\|Mulcahy, H\|Tighe, O\|Bennett, M A\|Kay, E W\|O'Donoghue, D P\|Leader, M\|Croke, D T
PMID:	10644313

234.
Journal:	Carcinogenesis. 2000 Feb;21(2):307-9.
Title:	Animal products and K-ras codon 12 and 13 mutations in colon carcinomas.
Author:	Kampman, E\|Voskuil, D W\|van Kraats, A A\|Balder, H F\|van Muijen, G N\|Goldbohm, R A\|van't Veer, P
PMID:	10657973

235.
Journal:	Oncol Rep. 2000 Mar-Apr;7(2):233-9.
Title:	pS2 expression as a possible diagnostic marker of colorectal carcinoma in ulcerative colitis.
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PMID:	10671663

236.
Journal:	Hepatogastroenterology. 2000 Jan-Feb;47(31):57-70.
Title:	Chronic inflammatory bowel disease and cancer.
Author:	Pohl, C\|Hombach, A\|Kruis, W
PMID:	10690586

237.
Journal:	Dis Colon Rectum. 2000 Feb;43(2):155-9; discussion 159-62.
Title:	Molecular staging of colorectal cancer: K-ras mutation analysis of lymph nodes upstages Dukes B patients.
Author:	Thebo, J S\|Senagore, A J\|Reinhold, D S\|Stapleton, S R
PMID:	10696887

238.
Journal:	Mol Carcinog. 2000 Mar;27(3):210-8.
Title:	Azoxymethane induces KI-ras activation in the tumor resistant AKR/J mouse colon.
Author:	Bolt, A B\|Papanikolaou, A\|Delker, D A\|Wang, Q S\|Rosenberg, D W
PMID:	10708483

239.
Journal:	Br J Cancer. 2000 Feb;82(4):905-12.
Title:	Manumycin inhibits ras signal transduction pathway and induces apoptosis in COLO320-DM human colon tumour cells.
Author:	Di Paolo, A\|Danesi, R\|Nardini, D\|Bocci, G\|Innocenti, F\|Fogli, S\|Barachini, S\|Marchetti, A\|Bevilacqua, G\|Del Tacca, M
PMID:	10732765

240.
Journal:	J Cell Biochem Suppl. 2000;34:35-9.
Title:	Utilization of K-ras mutations identified in stool DNA for the early detection of colorectal cancer.
Author:	Lev, Z\|Kislitsin, D\|Rennert, G\|Lerner, A
PMID:	10762013

241.
Journal:	Cancer Gene Ther. 2000 Mar;7(3):495-500.
Title:	Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells.
Author:	Funato, T\|Ishii, T\|Kambe, M\|Scanlon, K J\|Sasaki, T
PMID:	10766356

242.
Journal:	Oncol Rep. 2000 May-Jun;7(3):501-8.
Title:	Colitis-related rat colon carcinogenesis induced by 1-hydroxy-anthraquinone and methylazoxymethanol acetate (Review).
Author:	Tanaka, T\|Kohno, H\|Murakami, M\|Shimada, R\|Kagami, S
PMID:	10767359

243.
Journal:	Cancer Res. 2000 May 1;60(9):2368-71.
Title:	Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Author:	Esteller, M\|Toyota, M\|Sanchez-Cespedes, M\|Capella, G\|Peinado, M A\|Watkins, D N\|Issa, J P\|Sidransky, D\|Baylin, S B\|Herman, J G
PMID:	10811111

244.
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Title:	Somatic mutation screening: identification of individuals harboring K-ras mutations with the use of plasma DNA.
Author:	Kopreski, M S\|Benko, F A\|Borys, D J\|Khan, A\|McGarrity, T J\|Gocke, C D
PMID:	10841827

245.
Journal:	Clin Cancer Res. 2000 Jun;6(6):2129-37.
Title:	Detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer.
Author:	Sorenson, G D
PMID:	10873061

246.
Journal:	Mol Pathol. 2000 Feb;53(1):24-30.
Title:	p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women.
Author:	Servomaa, K\|Kiuru, A\|Kosma, V M\|Hirvikoski, P\|Rytomaa, T
PMID:	10884918

247.
Journal:	Eur J Cancer. 2000 May;36(8):1008-15.
Title:	p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer.
Author:	Bouzourene, H\|Gervaz, P\|Cerottini, J P\|Benhattar, J\|Chaubert, P\|Saraga, E\|Pampallona, S\|Bosman, F T\|Givel, J C
PMID:	10885605

248.
Journal:	Rinsho Byori. 2000 Jun;48(6):547-53.
Title:	[Characteristics of plasma DNA and its application for detection of K-ras gene mutation].
Author:	Hayashi, T\|Sugahara, K\|Dateki, N\|Yamada, Y\|Sudou, R\|Kanematsu, T\|Kamihira, S
PMID:	10897674

249.
Journal:	Anticancer Res. 2000 May-Jun;20(3A):1695-701.
Title:	The prognostic value of the presence of mutations at the codons 12, 13, 61 of K-ras oncogene in colorectal cancer.
Author:	Pajkos, G\|Kiss, I\|Sandor, J\|Ember, I\|Kishazi, P
PMID:	10928094

250.
Journal:	Br J Cancer. 2000 Sep;83(6):833-9.
Title:	Ribozyme-mediated inactivation of mutant K-ras oncogene in a colon cancer cell line.
Author:	Tokunaga, T\|Tsuchida, T\|Kijima, H\|Okamoto, K\|Oshika, Y\|Sawa, N\|Ohnishi, Y\|Yamazaki, H\|Miura, S\|Ueyama, Y\|Nakamura, M
PMID:	10952790

251.
Journal:	Anticancer Res. 2000 Jul-Aug;20(4):2469-72.
Title:	Clinical value of bile for the detection of mutant K-ras from colorectal liver metastases.
Author:	de Kok, J B\|Swinkels, D W\|Ruers, T J
PMID:	10953312

252.
Journal:	Int J Cancer. 2000 Jul 20;89(4):337-44.
Title:	Detection of tumor cells in blood using CD45 magnetic cell separation followed by nested mutant allele-specific amplification of p53 and K-ras genes in patients with colorectal cancer.
Author:	Iinuma, H\|Okinaga, K\|Adachi, M\|Suda, K\|Sekine, T\|Sakagawa, K\|Baba, Y\|Tamura, J\|Kumagai, H\|Ida, A
PMID:	10956407

253.
Journal:	Nature. 2000 Aug 24;406(6798):897-902.
Title:	Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma.
Author:	Sasaki, T\|Irie-Sasaki, J\|Horie, Y\|Bachmaier, K\|Fata, J E\|Li, M\|Suzuki, A\|Bouchard, D\|Ho, A\|Redston, M\|Gallinger, S\|Khokha, R\|Mak, T W\|Hawkins, P T\|Stephens, L\|Scherer, S W\|Tsao, M\|Penninger, J M
PMID:	10972292

254.
Journal:	Dig Liver Dis. 2000 Mar;32(2):131-6.
Title:	K-ras and p53 mutations in DNA extracted from colonic epithelial cells exfoliated in faeces of patients with colorectal cancer.
Author:	Notarnicola, M\|Cavallini, A\|Cardone, R\|Pezzolla, F\|Demma, I\|Di Leo, A
PMID:	10975788

255.
Journal:	World J Surg. 2000 Sep;24(9):1091-7.
Title:	Colorectal carcinogenesis based on molecular biology of early colorectal cancer, with special reference to nonpolypoid (superficial) lesions.
Author:	Watanabe, T\|Muto, T
PMID:	11036287

256.
Journal:	Am J Gastroenterol. 2000 Oct;95(10):2953-7.
Title:	Impact of KRAS and TP53 mutations on survival in patients with left- and right-sided Dukes' C colon cancer.
Author:	Bleeker, W A\|Hayes, V M\|Karrenbeld, A\|Hofstra, R M\|Hermans, J\|Buys, C C\|Plukker, J T
PMID:	11051374

257.
Journal:	Mol Med. 2000 Aug;6(8):693-704.
Title:	A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells.
Author:	Halaschek-Wiener, J\|Wacheck, V\|Schlagbauer-Wadl, H\|Wolff, K\|Kloog, Y\|Jansen, B
PMID:	11055588

258.
Journal:	Chirurg. 2000 Oct;71(10):1230-4; discussion 1234-5.
Title:	["Field cancerization"--an additional phenomenon in development of colon tumors? K-ras codon 12 mutations in normal colonic mucosa of patients with colorectal neoplasms].
Author:	Aivado, M\|Gynes, M\|Gorelov, V\|Schmidt, W U\|Roher, H D\|Goretzki, P E
PMID:	11077584

259.
Journal:	Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1155-62.
Title:	Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine.
Author:	Lawson, K R\|Ignatenko, N A\|Piazza, G A\|Cui, H\|Gerner, E W
PMID:	11097222

260.
Journal:	Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1193-7.
Title:	Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study.
Author:	Samowitz, W S\|Curtin, K\|Schaffer, D\|Robertson, M\|Leppert, M\|Slattery, M L
PMID:	11097226

261.
Journal:	J Gastroenterol Hepatol. 2000 Oct;15(10):1151-7.
Title:	Analysis of K-ras codon 12 mutations and p53 overexpression in colorectal nodule-aggregating tumors.
Author:	Kusaka, T\|Fukui, H\|Sano, Y\|Ueda, Y\|Chiba, T\|Fujimori, T
PMID:	11106095

262.
Journal:	Cancer Res. 2000 Dec 1;60(23):6607-10.
Title:	Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells.
Author:	Taylor, M T\|Lawson, K R\|Ignatenko, N A\|Marek, S E\|Stringer, D E\|Skovan, B A\|Gerner, E W
PMID:	11118042

263.
Journal:	J Clin Pathol. 2000 Nov;53(11):841-5.
Title:	Pathogenesis of non-familial colorectal carcinomas with high microsatellite instability.
Author:	Shitoh, K\|Konishi, F\|Miyaki, M\|Iijima, T\|Furukawa, T\|Tsukamoto, T\|Nagai, H
PMID:	11127266

264.
Journal:	Ann Surg Oncol. 2000 Dec;7(10):727-31.
Title:	Specific c-K-ras gene mutations as a tumor-response marker in locally advanced rectal cancer treated with preoperative chemoradiotherapy.
Author:	Luna-Perez, P\|Segura, J\|Alvarado, I\|Labastida, S\|Santiago-Payan, H\|Quintero, A
PMID:	11129419

265.
Journal:	Int J Colorectal Dis. 2000 Nov;15(5-6):275-81.
Title:	Flat-elevated and depressed, subtypes of flat early colorectal cancers, should be distinguished by their pathological features.
Author:	Sakashita, M\|Aoyama, N\|Maekawa, S\|Kuroda, K\|Shirasaka, D\|Ichihara, T\|Kuroda, Y\|Minami, R\|Maeda, S\|Kasuga, M
PMID:	11151430

266.
Journal:	Cancer Res. 2000 Dec 15;60(24):6886-9.
Title:	Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.
Author:	Baba, I\|Shirasawa, S\|Iwamoto, R\|Okumura, K\|Tsunoda, T\|Nishioka, M\|Fukuyama, K\|Yamamoto, K\|Mekada, E\|Sasazuki, T
PMID:	11156386

267.
Journal:	Cancer Res. 2000 Dec 15;60(24):6935-41.
Title:	Associations between dietary intake and Ki-ras mutations in colon tumors: a population-based study.
Author:	Slattery, M L\|Curtin, K\|Anderson, K\|Ma, K N\|Edwards, S\|Leppert, M\|Potter, J\|Schaffer, D\|Samowitz, W S
PMID:	11156393

268.
Journal:	Int J Biol Markers. 2000 Oct-Dec;15(4):300-7.
Title:	Molecular detection of codon 12 K-RAS mutations in circulating DNA from serum of colorectal cancer patients.
Author:	Salbe, C\|Trevisiol, C\|Ferruzzi, E\|Mancuso, T\|Nascimbeni, R\|Di Fabio, F\|Salerni, B\|Dittadi, R
PMID:	11192825

269.
Journal:	Exp Lung Res. 2000 Dec;26(8):581-93.
Title:	Use of p53 transgenic mice in the development of cancer models for multiple purposes.
Author:	Lubet, R A\|Zhang, Z\|Wiseman, R W\|You, M
PMID:	11195457

270.
Journal:	Exp Lung Res. 2000 Dec;26(8):709-30.
Title:	Differential sensitivity to lung tumorigenesis following transplacental exposure of mice to polycyclic hydrocarbons, heterocyclic amines, and lung tumor promoters.
Author:	Miller, M S\|Gressani, K M\|Leone-Kabler, S\|Townsend, A J\|Malkinson, A M\|O'Sullivan, M G
PMID:	11195466

271.
Journal:	Neoplasma. 2000;47(6):335-41.
Title:	A double germline mutations in the APC and p53 genes.
Author:	Zajac, V\|Tomka, M\|Ilencikova, D\|Majek, P\|Stevurkova, V\|Kirchhoff, T
PMID:	11263856

272.
Journal:	Anal Cell Pathol. 2000;21(2):49-57.
Title:	Intratumor heterogeneity of k-ras and p53 mutations among human colorectal adenomas containing early cancer.
Author:	Giaretti, W\|Rapallo, A\|Sciutto, A\|Macciocu, B\|Geido, E\|Hermsen, M A\|Postma, C\|Baak, J P\|Williams, R A\|Meijer, G A
PMID:	11310641

273.
Journal:	J Biol Chem. 2001 Jan 12;276(2):1555-63.
Title:	Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III.
Author:	Yan, Z\|Deng, X\|Friedman, E
PMID:	11029459

274.
Journal:	Clin Chem. 2001 Feb;47(2):186-94.
Title:	K-ras mutation detection by hybridization to a polypyrrole DNA chip.
Author:	Lopez-Crapez, E\|Livache, T\|Marchand, J\|Grenier, J
PMID:	11159765

275.
Journal:	Am J Surg Pathol. 2001 Feb;25(2):177-84.
Title:	Hyperplastic polyposis: association with colorectal cancer.
Author:	Leggett, B A\|Devereaux, B\|Biden, K\|Searle, J\|Young, J\|Jass, J
PMID:	11176066

276.
Journal:	J Clin Oncol. 2001 Jan 15;19(2):299-304.
Title:	K-ras and p16 aberrations confer poor prognosis in human colorectal cancer.
Author:	Esteller, M\|Gonzalez, S\|Risques, R A\|Marcuello, E\|Mangues, R\|Germa, J R\|Herman, J G\|Capella, G\|Peinado, M A
PMID:	11208819

277.
Journal:	Eur J Surg Oncol. 2001 Feb;27(1):80-7.
Title:	Relevance of Ki-67 antigen expression and K-ras mutation in colorectal liver metastases.
Author:	Petrowsky, H\|Sturm, I\|Graubitz, O\|Kooby, D A\|Staib-Sebler, E\|Gog, C\|Kohne, C H\|Hillebrand, T\|Daniel, P T\|Fong, Y\|Lorenz, M
PMID:	11237496

278.
Journal:	J Pathol. 2001 Mar;193(3):303-9.
Title:	Molecular changes in the Ki-ras and APC genes in colorectal adenomas and carcinomas arising in the same patient.
Author:	Zauber, N P\|Sabbath-Solitare, M\|Marotta, S P\|Zauber, A G\|Bishop, D T
PMID:	11241408

279.
Journal:	Dis Colon Rectum. 2001 Mar;44(3):358-63.
Title:	Prognostic significance of K-ras and TP53 mutations in the role of adjuvant chemotherapy on survival in patients with Dukes C colon cancer.
Author:	Bleeker, W A\|Hayes, V M\|Karrenbeld, A\|Hofstra, R M\|Verlind, E\|Hermans, J\|Poppema, S\|Buys, C H\|Plukker, J T
PMID:	11289281

280.
Journal:	Mol Ther. 2001 Apr;3(4):491-9.
Title:	Suppression of colorectal cancer growth using an adenovirus vector expressing an antisense K-ras RNA.
Author:	Nakano, M\|Aoki, K\|Matsumoto, N\|Ohnami, S\|Hatanaka, K\|Hibi, T\|Terada, M\|Yoshida, T
PMID:	11319909

281.
Journal:	Clin Cancer Res. 2001 May;7(5):1118-26.
Title:	Biomarkers for early detection of colon cancer.
Author:	Srivastava, S\|Verma, M\|Henson, D E
PMID:	11350874

282.
Journal:	Int J Colorectal Dis. 2001 Apr;16(2):108-11.
Title:	Tumour-derived mutated K-ras codon 12 expression in regional lymph nodes of stage II colorectal cancer patients is not associated with increased risk of cancer-related death.
Author:	Clarke, G A\|Ryan, E\|Crowe, J P\|O'Keane, J C\|MacMathuna, P
PMID:	11355316

283.
Journal:	Cancer Res. 2001 May 15;61(10):4003-9.
Title:	Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.
Author:	Hostein, I\|Robertson, D\|DiStefano, F\|Workman, P\|Clarke, P A
PMID:	11358818

284.
Journal:	J Clin Oncol. 2001 Jun 1;19(11):2837-43.
Title:	Discordance between K-ras mutations in bone marrow micrometastases and the primary tumor in colorectal cancer.
Author:	Tortola, S\|Steinert, R\|Hantschick, M\|Peinado, M A\|Gastinger, I\|Stosiek, P\|Lippert, H\|Schlegel, W\|Reymond, M A
PMID:	11387355

285.
Journal:	Cancer Res. 2001 Jun 15;61(12):4689-92.
Title:	Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
Author:	Esteller, M\|Risques, R A\|Toyota, M\|Capella, G\|Moreno, V\|Peinado, M A\|Baylin, S B\|Herman, J G
PMID:	11406538

286.
Journal:	Ann Surg Oncol. 2001 Jun;8(5):407-12.
Title:	Clinical significance of K-Ras mutations in intraoperative tumor drainage blood from patients with colorectal carcinoma.
Author:	Etoh, T\|Ueo, H\|Inoue, H\|Sato, K\|Utsunomiya, T\|Barnard, G F\|Kitano, S\|Mori, M
PMID:	11407514

287.
Journal:	Exp Mol Pathol. 2001 Jun;70(3):289-301.
Title:	Detection of the mutated K-Ras biomarker in colorectal carcinoma.
Author:	Doolittle, B R\|Emanuel, J\|Tuttle, C\|Costa, J
PMID:	11418008

288.
Journal:	Digestion. 2001;63(4):229-33.
Title:	K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias.
Author:	Heinzlmann, M\|Neynaber, S\|Heldwein, W\|Folwaczny, C
PMID:	11435722

289.
Journal:	Clin Chem Lab Med. 2001 Jun;39(6):501-4.
Title:	Melting temperature analysis as quantitative method for detection of point mutations.
Author:	Porcelli, B\|Frosi, B\|Terzuoli, L\|Arezzini, L\|Pagani, R\|Civitelli, S\|Tanzini, G\|Orlando, C\|Pazzagli, M\|Marziliano, N\|Da Prato, L
PMID:	11506461

290.
Journal:	Am Surg. 2001 Aug;67(8):802-5.
Title:	K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells.
Author:	Thebo, J S\|Senagore, A J\|Krygier, S\|Luchtefeld, M A
PMID:	11510588

291.
Journal:	Mol Cell Probes. 2001 Oct;15(5):243-7.
Title:	A modified mutagenic PCR-RFLP method for K-ras codon 12 and 13 mutations detection in NSCLC patients.
Author:	Hatzaki, A\|Razi, E\|Anagnostopoulou, K\|Iliadis, K\|Kodaxis, A\|Papaioannou, D\|Labropoulos, S\|Vasilaki, M\|Kosmidis, P\|Saetta, A\|Mihalatos, M\|Nasioulas, G
PMID:	11735295

292.
Journal:	J Pathol. 2001 Dec;195(5):543-8.
Title:	Ki-ras mutation type and the survival benefit from adjuvant chemotherapy in Dukes' C colorectal cancer.
Author:	Gnanasampanthan, G\|Elsaleh, H\|McCaul, K\|Iacopetta, B
PMID:	11745689

293.
Journal:	Cytometry. 2001 Dec 15;46(6):345-50.
Title:	Analysis of Ki-ras gene mutations associated with DNA diploid, aneuploid, and multiploid colorectal carcinomas using a crypt isolation technique.
Author:	Sugai, T\|Habano, W\|Nakamura, S\|Jiao, Y F\|Higuchi, T\|Inomata, M\|Chiba, T
PMID:	11754204

294.
Journal:	World J Gastroenterol. 2001 Jun;7(3):352-6.
Title:	APC and K-ras gene mutation in aberrant crypt foci of human colon.
Author:	Yuan, P\|Sun, M H\|Zhang, J S\|Zhu, X Z\|Shi, D R
PMID:	11819789

295.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2001 Feb;30(1):35-8.
Title:	[Mutations of APC and K-ras gene in aberrant crypt foci from human colon].
Author:	Yuan, P\|Sun, M\|Zhang, J\|Zhu, X\|Shi, D
PMID:	11866955

296.
Journal:	East Afr Med J. 2001 Jul;78(7 Suppl):S48-9.
Title:	Lessons learned from colorectal model of tumourigenesis.
Author:	Wakhisi, J
PMID:	11957250

297.
Journal:	Surgery. 2002 Feb;131(2):190-7.
Title:	Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer.
Author:	Gervaz, Pascal\|Cerottini, Jean-Philippe\|Bouzourene, Hanifa\|Hahnloser, Dieter\|Doan, Christy L\|Benhattar, Jean\|Chaubert, Pascal\|Secic, Michelle\|Gillet, Michel\|Carethers, John M
PMID:	11854698

298.
Journal:	Int J Cancer. 2002 Feb 20;97(6):823-7.
Title:	Associations between family history of colorectal cancer and genetic alterations in tumors.
Author:	Slattery, Martha L\|Curtin, Karen\|Schaffer, Donna\|Anderson, Kristen\|Samowitz, Wade
PMID:	11857362

299.
Journal:	Clin Chim Acta. 2002 Apr;318(1-2):107-12.
Title:	A simple method of detecting K-ras point mutations in stool samples for colorectal cancer screening using one-step polymerase chain reaction/restriction fragment length polymorphism analysis.
Author:	Nishikawa, Takashi\|Maemura, Kentaro\|Hirata, Ichiro\|Matsuse, Ryouichi\|Morikawa, Hiroshi\|Toshina, Ken\|Murano, Mitsuyuki\|Hashimoto, Keiichi\|Nakagawa, Yoshihito\|Saitoh, Osamu\|Uchida, Kazuo\|Katsu, Kenichi
PMID:	11880119

300.
Journal:	Int J Mol Med. 2002 May;9(5):485-8.
Title:	Frequent polymorphism of peroxisome proliferator activated receptor gamma gene in colorectal cancer containing wild-type K-ras gene.
Author:	Tomita, Shigeki\|Kawamata, Hitoshi\|Imura, Johji\|Omotehara, Fumie\|Ueda, Yoshihiko\|Fujimori, Takahiro
PMID:	11956653

301.
Journal:	Int J Cancer. 2002 Jun 1;99(4):597-602.
Title:	Prognostic significance of p53 mutations in colon cancer at the population level.
Author:	Samowitz, Wade S\|Curtin, Karen\|Ma, Khe-ni\|Edwards, Sandra\|Schaffer, Donna\|Leppert, Mark F\|Slattery, Martha L
PMID:	11992552

302.
Journal:	Anal Biochem. 2002 May 15;304(2):200-5.
Title:	Mutation detection in KRAS Exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries.
Author:	Bjorheim, Jens\|Minarik, Marek\|Gaudernack, Gustav\|Ekstrom, Per Olaf
PMID:	12009696

303.
Journal:	Int J Oncol. 2002 Jun;20(6):1263-8.
Title:	Frequent detection of K-ras mutation in stool samples of colorectal carcinoma patients after improved DNA extraction: comparison with tissue samples.
Author:	Ito, Yasushi\|Kobayashi, Susumu\|Taniguchi, Tetsushi\|Kainuma, Osamu\|Hara, Tsuyosi\|Ochiai, Takenori
PMID:	12012008

304.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G932-6.
Title:	Age-associated loss of heterozygosity of tumor suppressor genes in the gastric mucosa of humans.
Author:	Moragoda, Lathika\|Jaszewski, Richard\|Kulkarni, Prasad\|Majumdar, Adhip P N
PMID:	12016117

305.
Journal:	Anticancer Res. 2002 Jan-Feb;22(1A):171-5.
Title:	Effect of vaccination with mutant KRAS peptides on rat colon carcinogenesis induced by azoxymethane.
Author:	Paulsen, Jan Erik\|Bjorheim, Jens\|Roe, Janne\|Eide, Tor Jacob\|Alexander, Jan\|Gaudernack, Gustav
PMID:	12017282

306.
Journal:	Oncogene. 2002 May 23;21(23):3792-5.
Title:	K-ras mutations and RASSF1A promoter methylation in colorectal cancer.
Author:	van Engeland, Manon\|Roemen, Guido M J M\|Brink, Mirian\|Pachen, Marco M M\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Arends, Jan-Willem\|van den Brandt, Piet A\|de Goeij, Anton F P M\|Herman, James G
PMID:	12032847

307.
Journal:	Am J Clin Pathol. 2002 Jun;117(6):908-15.
Title:	High apoptotic activity and low epithelial cell proliferation with underexpression of p21(WAF1/CIP1) and p27Kip1 of mucinous carcinomas of the colorectum: comparison with well-differentiated type.
Author:	Akino, Fumiyuki\|Mitomi, Hiroyuki\|Nakamura, Takatoshi\|Ohtani, Yoshimasa\|Ichinoe, Masaaki\|Okayasu, Isao
PMID:	12047142

308.
Journal:	J Gastroenterol. 2002;37(5):354-62.
Title:	Colorectal carcinoma with special reference to growth pattern classifications: clinicopathologic characteristics and genetic changes.
Author:	Kurahashi, Toshinori\|Kaneko, Kazuhiro\|Makino, Reiko\|Mitamura, Keiji
PMID:	12051534

309.
Journal:	J Pathol. 2002 May;197(1):128-35.
Title:	Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on beta-catenin protein dysregulation, but not k-ras mutation.
Author:	Wong, N A C S\|Morris, R G\|McCondochie, A\|Bader, S\|Jodrell, D I\|Harrison, D J
PMID:	12081197

310.
Journal:	Jpn J Clin Oncol. 2002 Jun;32(6):196-201.
Title:	Increased frequency of p53 mutation in sporadic colorectal cancer from cigarette smokers.
Author:	Miyaki, Michiko\|Iijima, Takeru\|Ishii, Reiko\|Kita, Yumi\|Koike, Morio\|Kuroki, Toshio\|Mori, Takeo
PMID:	12110635

311.
Journal:	Jpn J Clin Oncol. 2002 Jun;32(6):219-21.
Title:	Concurrent mutations of K-ras oncogene at codons 12 and 22 in colon cancer.
Author:	Miyakura, Yasuyuki\|Sugano, Kokichi\|Fukayama, Noriko\|Konishi, Fumio\|Nagai, Hideo
PMID:	12110640

312.
Journal:	Int J Cancer. 2002 Aug 10;100(5):542-8.
Title:	Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis.
Author:	Lecomte, Thierry\|Berger, Anne\|Zinzindohoue, Franck\|Micard, Stephanie\|Landi, Bruno\|Blons, Helene\|Beaune, Philippe\|Cugnenc, Paul-Henri\|Laurent-Puig, Pierre
PMID:	12124803

313.
Journal:	Gastroenterology. 2002 Aug;123(2):492-504.
Title:	Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice.
Author:	Janssen, Klaus-Peter\|el-Marjou, Fatima\|Pinto, Daniel\|Sastre, Xavier\|Rouillard, Dany\|Fouquet, Coralie\|Soussi, Thierry\|Louvard, Daniel\|Robine, Sylvie
PMID:	12145803

314.
Journal:	J Exp Clin Cancer Res. 2002 Jun;21(2):203-11.
Title:	Molecular changes in the early stage of colon carcinogenesis in rats treated with azoxymethane.
Author:	Kishimoto, Y\|Morisawa, T\|Hosoda, A\|Shiota, G\|Kawasaki, H\|Hasegawa, J
PMID:	12148579

315.
Journal:	Cancer Causes Control. 2002 Aug;13(6):527-34.
Title:	GSTM-1 and NAT2 and genetic alterations in colon tumors.
Author:	Slattery, M L\|Curtin, Karen\|Ma, K\|Schaffer, Donna\|Potter, John\|Samowitz, Wade
PMID:	12195642

316.
Journal:	Nature. 2002 Aug 29;418(6901):934.
Title:	Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.
Author:	Rajagopalan, Harith\|Bardelli, Alberto\|Lengauer, Christoph\|Kinzler, Kenneth W\|Vogelstein, Bert\|Velculescu, Victor E
PMID:	12198537

317.
Journal:	FASEB J. 2002 Oct;16(12):1642-4.
Title:	Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice.
Author:	Guerrero, Silvia\|Figueras, Agnes\|Casanova, Isolda\|Farre, Lourdes\|Lloveras, Belen\|Capella, Gabriel\|Trias, Manuel\|Mangues, Ramon
PMID:	12207005

318.
Journal:	Gastroenterology. 2002 Oct;123(4):1109-19.
Title:	Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability.
Author:	Hermsen, Mario\|Postma, Cindy\|Baak, Jan\|Weiss, Marjan\|Rapallo, Anna\|Sciutto, Andrea\|Roemen, Guido\|Arends, Jan-Willem\|Williams, Richard\|Giaretti, Walter\|De Goeij, Anton\|Meijer, Gerrit
PMID:	12360473

319.
Journal:	BMC Cancer. 2002 Oct 14;2:25.
Title:	Predominance of CIN versus MSI in the development of rectal cancer at young age.
Author:	Fernebro, Eva\|Halvarsson, Britta\|Baldetorp, Bo\|Nilbert, Mef
PMID:	12379157

320.
Journal:	J Mol Diagn. 2002 Nov;4(4):191-200.
Title:	Molecular validation of the modified Vienna classification of colorectal tumors.
Author:	Sugai, Tamotsu\|Habano, Wataru\|Uesugi, Noriyuki\|Jiao, Yu-Fei\|Nakamura, Shin-ichi\|Sato, Kimihiko\|Chiba, Toshimi\|Ishii, Motohiro
PMID:	12411586

321.
Journal:	J Nutr. 2002 Nov;132(11 Suppl):3518S-3521S.
Title:	DNA alkylation and repair in the large bowel: animal and human studies.
Author:	Povey, Andrew C\|Badawi, Alaa F\|Cooper, Donald P\|Hall, C Nicholas\|Harrison, Kathryn L\|Jackson, Peta E\|Lees, Nicholas P\|O'Connor, Peter J\|Margison, Geoffrey P
PMID:	12421880

322.
Journal:	Cancer Res. 2002 Nov 15;62(22):6451-5.
Title:	Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
Author:	Yuen, Siu T\|Davies, Helen\|Chan, Tsun L\|Ho, Judy W\|Bignell, Graham R\|Cox, Charles\|Stephens, Philip\|Edkins, Sarah\|Tsui, Wendy W\|Chan, Annie S\|Futreal, P Andrew\|Stratton, Michael R\|Wooster, Richard\|Leung, Suet Y
PMID:	12438234

323.
Journal:	Jpn J Cancer Res. 2002 Nov;93(11):1266-9.
Title:	Detection of tumor DNA in serum of colorectal cancer patients.
Author:	Ito, Seiji\|Hibi, Kenji\|Nakayama, Hiroshi\|Kodera, Yasuhiro\|Ito, Katsuki\|Akiyama, Seiji\|Nakao, Akimasa
PMID:	12460469

324.
Journal:	Genes Chromosomes Cancer. 2003 Jan;36(1):17-25.
Title:	Methylation profile of the MLH1 promoter region and their relationship to colorectal carcinogenesis.
Author:	Miyakura, Yasuyuki\|Sugano, Kokichi\|Konishi, Fumio\|Fukayama, Noriko\|Igarashi, Seiji\|Kotake, Kenjiro\|Matsui, Takashi\|Koyama, Yasuo\|Maekawa, Masato\|Nagai, Hideo
PMID:	12461746

325.
Journal:	Gut. 2003 Jan;52(1):101-8.
Title:	A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up.
Author:	Ryan, B M\|Lefort, F\|McManus, R\|Daly, J\|Keeling, P W N\|Weir, D G\|Kelleher, D
PMID:	12477769

326.
Journal:	Mol Carcinog. 2003 Feb;36(2):45-52.
Title:	Exploring environmental causes of altered ras effects: fragmentation plus integration?
Author:	Porta, Miquel\|Ayude, Daniel\|Alguacil, Juan\|Jariod, Manuel
PMID:	12557259

327.
Journal:	Br J Cancer. 2003 Feb 10;88(3):413-9.
Title:	CpG island methylation is a common finding in colorectal cancer cell lines.
Author:	Suter, C M\|Norrie, M\|Ku, S L\|Cheong, K F\|Tomlinson, I\|Ward, R L
PMID:	12569385

328.
Journal:	Br J Cancer. 2003 Feb 24;88(4):530-6.
Title:	Specific T-cell immunity against Ki-ras peptides in patients with pancreatic and colorectal cancers.
Author:	Shono, Y\|Tanimura, H\|Iwahashi, M\|Tsunoda, T\|Tani, M\|Tanaka, H\|Matsuda, K\|Yamaue, H
PMID:	12592366

329.
Journal:	Int J Mol Med. 2003 Apr;11(4):485-90.
Title:	Telomeric repeat-length alterations in colorectal carcinoma are associated with loss of heterozygosity and point mutation in p53 gene.
Author:	Ohki, Shinji\|Onda, Masamitsu\|Fukushima, Toshihiko\|Takita, Kenichi\|Suzuki, Shinichi\|Hoshino, Masami\|Tsuchiya, Atsuo\|Abe, Rikiya\|Takenoshita, Seiichi
PMID:	12632102

330.
Journal:	Mol Cancer Res. 2003 Mar;1(5):393-401.
Title:	Met receptor overexpression and oncogenic Ki-ras mutation cooperate to enhance tumorigenicity of colon cancer cells in vivo.
Author:	Long, Isolde Seiden\|Han, Kathy\|Li, Ming\|Shirasawa, Senji\|Sasazuki, Takehiko\|Johnston, Michael\|Tsao, Ming-Sound
PMID:	12651912

331.
Journal:	Electrophoresis. 2003 Jan;24(1-2):63-9.
Title:	Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis.
Author:	Bjorheim, Jens\|Gaudernack, Gustav\|Giercksky, Karl-Erik\|Ekstrom, Per O
PMID:	12652573

332.
Journal:	Genes Chromosomes Cancer. 2003 Jun;37(2):207-13.
Title:	Near-diploid and near-triploid human sporadic colorectal adenocarcinomas differ for KRAS2 and TP53 mutational status.
Author:	Giaretti, Walter\|Venesio, Tiziana\|Sciutto, Andrea\|Prevosto, Claudia\|Geido, Elio\|Risio, Mauro
PMID:	12696070

333.
Journal:	Folia Histochem Cytobiol. 2003;41(2):97-100.
Title:	Evaluation of K-RAS gene in colorectal cancer.
Author:	Okulczyk, Bogna\|Piotrowski, Zdzislaw\|Kovalchuk, Oksana\|Niklinski, Jacek\|Chyczewski, Lech
PMID:	12722796

334.
Journal:	Carcinogenesis. 2003 Apr;24(4):703-10.
Title:	K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study.
Author:	Brink, Mirian\|de Goeij, Anton F P M\|Weijenberg, Matty P\|Roemen, Guido M J M\|Lentjes, Marjolein H F M\|Pachen, Marco M M\|Smits, Kim M\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van den Brandt, Piet A
PMID:	12727799

335.
Journal:	Cell Mol Life Sci. 2003 Mar;60(3):495-506.
Title:	Murine models of colorectal cancer: studying the role of oncogenic K-ras.
Author:	Janssen, K P
PMID:	12737309

336.
Journal:	J Biol Chem. 2003 Jul 25;278(30):28167-72.
Title:	Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration.
Author:	Ikeda, Wataru\|Kakunaga, Shigeki\|Itoh, Shinsuke\|Shingai, Tatsushi\|Takekuni, Kyoji\|Satoh, Keiko\|Inoue, Yoko\|Hamaguchi, Akiko\|Morimoto, Koji\|Takeuchi, Masakazu\|Imai, Toshio\|Takai, Yoshimi
PMID:	12740392

337.
Journal:	Clin Colorectal Cancer. 2003 May;3(1):47-53.
Title:	Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia.
Author:	Tagore, Kuldeep S\|Lawson, Michael J\|Yucaitis, Joy A\|Gage, Rhonda\|Orr, Tashia\|Shuber, Anthony P\|Ross, Michael E
PMID:	12777192

338.
Journal:	Mol Pathol. 2003 Jun;56(3):137-40.
Title:	Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchronous metastases compared with the findings in accompanying adenomas.
Author:	Zauber, P\|Sabbath-Solitare, M\|Marotta, S P\|Bishop, D T
PMID:	12782759

339.
Journal:	Zhonghua Nei Ke Za Zhi. 2003 Feb;42(2):77-80.
Title:	[Study of angiogenesis in human colorectal carcinoma and its modulation by p53 and K-ras gene].
Author:	Zhong, Shi-shun\|Zhang, Zhen-shu\|Li, Shu-mei\|Deng, Hai-jun\|Ma, Qiang
PMID:	12783699

340.
Journal:	Oncol Rep. 2003 Jul-Aug;10(4):859-66.
Title:	Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene.
Author:	Yamada, Kanae\|Zhong, Xiaoling\|Kanazawa, Shinsaku\|Koike, Junichi\|Tsujita, Kazunori\|Hemmi, Hiromichi
PMID:	12792735

341.
Journal:	Int J Cancer. 2003 Aug 20;106(2):187-97.
Title:	Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin.
Author:	Germann, Anja\|Dihlmann, Susanne\|Hergenhahn, Manfred\|Doeberitz, Magnus von Knebel\|Koesters, Robert
PMID:	12800193

342.
Journal:	Eur J Surg Oncol. 2003 Aug;29(6):491-6.
Title:	Distribution of genetic variants in preneoplastic areas of colorectal tumours.
Author:	Lindforss, U\|Papadogiannakis, N\|Zetterquist, H\|Lindberg, G\|Olivecrona, H
PMID:	12875854

343.
Journal:	Nutr Cancer. 2003;45(2):203-10.
Title:	Lignan precursors from flaxseed or rye bran do not protect against the development of intestinal neoplasia in ApcMin mice.
Author:	van Kranen, Henk J\|Mortensen, Alicja\|Sorensen, Ilona K\|van den Berg-Wijnands, Jolanda\|Beems, Rudolf\|Nurmi, Tarja\|Adlercreutz, Herman\|van Kreijl, Coen F
PMID:	12881015

344.
Journal:	Tumori. 2003 May-Jun;89(3):259-62.
Title:	Transitions and transversions in Ki-ras gene in colorectal cancers in Mexican patients.
Author:	Segura-Uribe, Julia\|Santiago-Payan, Hector\|Quintero, Angelina
PMID:	12908779

345.
Journal:	Clin Cancer Res. 2003 Aug 1;9(8):3073-9.
Title:	beta-Catenin and ras oncogenes detect most human colorectal cancer.
Author:	Zhang, Bin\|Ougolkov, Andrei\|Yamashita, Kaname\|Takahashi, Yutaka\|Mai, Masayoshi\|Minamoto, Toshinari
PMID:	12912959

346.
Journal:	Br J Cancer. 2003 Aug 18;89(4):707-12.
Title:	Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma.
Author:	Matsumoto, N\|Yoshida, T\|Yamashita, K\|Numata, Y\|Okayasu, I
PMID:	12915883

347.
Journal:	Cancer Res. 2003 Aug 15;63(16):4878-81.
Title:	BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.
Author:	Chan, Tsun L\|Zhao, Wei\|Leung, Suet Y\|Yuen, Siu T
PMID:	12941809

348.
Journal:	J Biol Chem. 2003 Nov 21;278(47):46278-87. Epub 2003 Sep 12.
Title:	Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression.
Author:	Klampfer, Lidija\|Huang, Jie\|Corner, Georgia\|Mariadason, John\|Arango, Diego\|Sasazuki, Takehiko\|Shirasawa, Senji\|Augenlicht, Leonard
PMID:	12972432

349.
Journal:	Cancer Res. 2003 Sep 1;63(17):5218-23.
Title:	Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin.
Author:	Shao, Jinyi\|Lee, Sean B\|Guo, Huiping\|Evers, B Mark\|Sheng, Hongmiao
PMID:	14500348

350.
Journal:	Int J Cancer. 2003 Nov 10;107(3):387-93.
Title:	High frequency of activated K-ras codon 15 mutant in colorectal carcinomas from Taiwanese patients.
Author:	Wang, Jaw-Yuan\|Hsieh, Jan-Sing\|Chen, Fang-Ming\|Yeh, Ching-Sheng\|Alexandersen, Ketil\|Huang, Tsung-Jen\|Chen, David c p\|Lin, Shiu-Ru
PMID:	14506738

351.
Journal:	Pathol Int. 2003 Dec;53(12):828-36.
Title:	Analysis of Ki-ras and p53 gene mutations in laterally spreading tumors of the colorectum.
Author:	Noro, Akihiro\|Sugai, Tamotsu\|Habano, Wataru\|Nakamura, Shin-ichi
PMID:	14629748

352.
Journal:	Clin Cancer Res. 2003 Nov 15;9(15):5660-5.
Title:	Immunohistochemical and mutational analyses of beta-catenin, Ki-ras, and p53 in two subtypes of colorectal mucinous carcinoma.
Author:	Ikeda, Satoshi\|Shimizu, Yosuke\|Fujimori, Masahiko\|Ishizaki, Yasuyo\|Kurihara, Takeshi\|Ojima, Yasutomo\|Okajima, Masazumi\|Asahara, Toshimasa
PMID:	14654549

353.
Journal:	World J Gastroenterol. 2003 Dec;9(12):2642-9.
Title:	Aberrant crypt foci as microscopic precursors of colorectal cancer.
Author:	Cheng, Lei\|Lai, Mao-De
PMID:	14669304

354.
Journal:	J Gastroenterol. 2003;38(12):1185-8.
Title:	Genetic analysis of radiation-associated rectal cancer.
Author:	Tsuji, Takashi\|Sawai, Terumitsu\|Nakagoe, Tohru\|Hidaka, Shigekazu\|Shibasaki, Shinichi\|Tanaka, Kenji\|Nanashima, Atsushi\|Yamaguchi, Hiroyuki\|Yasutake, Tohru\|Tagawa, Yutaka
PMID:	14714259

355.
Journal:	Comp Med. 2003 Dec;53(6):633-8.
Title:	Analysis of beta-catenin, Ki-ras, and microsatellite stability in azoxymethane-induced colon tumors of BDIX/Orl Ico rats.
Author:	Sorensen, Nanna Moller\|Kobaek-Larsen, Morten\|Bonne, Anita\|van Zutphen, Bert\|Fenger, Claus\|Kristiansen, Karsten\|Ritskes-Hoitinga, Merel
PMID:	14727811

356.
Journal:	J Cell Physiol. 2004 Feb;198(2):277-94.
Title:	Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines.
Author:	Liou, James S\|Chen, James S\|Faller, Douglas V
PMID:	14603530

357.
Journal:	J Hum Genet. 2004;49(1):46-52. Epub 2003 Dec 13.
Title:	Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells.
Author:	Inokuchi, Junichi\|Komiya, Misako\|Baba, Iwai\|Naito, Seiji\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	14673706

358.
Journal:	Carcinogenesis. 2004 Apr;25(4):527-33. Epub 2003 Dec 19.
Title:	Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.
Author:	Fransen, Karin\|Klintenas, Maria\|Osterstrom, Anna\|Dimberg, Jan\|Monstein, Hans-Jurg\|Soderkvist, Peter
PMID:	14688025

359.
Journal:	Carcinogenesis. 2004 Apr;25(4):605-12.
Title:	o-Nitrotoluene-induced large intestinal tumors in B6C3F1 mice model human colon cancer in their molecular pathogenesis.
Author:	Sills, R C\|Hong, H L\|Flake, G\|Moomaw, C\|Clayton, N\|Boorman, G A\|Dunnick, J\|Devereux, T R
PMID:	14688030

360.
Journal:	Genes Chromosomes Cancer. 2004 Feb;39(2):138-42.
Title:	Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation.
Author:	Domingo, Enric\|Espin, Eloi\|Armengol, Manel\|Oliveira, Carla\|Pinto, Mafalda\|Duval, Alex\|Brennetot, Caroline\|Seruca, Raquel\|Hamelin, Richard\|Yamamoto, Hiroyuki\|Schwartz, Simo Jr
PMID:	14695993

361.
Journal:	Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):267-71.
Title:	Celecoxib but not rofecoxib inhibits the growth of transformed cells in vitro.
Author:	Kazanov, Diana\|Dvory-Sobol, Hadas\|Pick, Marjorie\|Liberman, Eliezer\|Strier, Ludmila\|Choen-Noyman, Efrat\|Deutsch, Varda\|Kunik, Talya\|Arber, Nadir
PMID:	14734479

362.
Journal:	Int J Cancer. 2004 Mar 20;109(2):265-73.
Title:	MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma.
Author:	Atkins, Derek\|Breuckmann, Aldona\|Schmahl, Gerd E\|Binner, Priska\|Ferrone, Soldano\|Krummenauer, Frank\|Storkel, Stephan\|Seliger, Barbara
PMID:	14750179

363.
Journal:	Mol Carcinog. 2004 Feb;39(2):91-102.
Title:	Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells.
Author:	Ignatenko, Natalia A\|Babbar, Naveen\|Mehta, Dipti\|Casero, Robert A Jr\|Gerner, Eugene W
PMID:	14750214

364.
Journal:	Eur J Clin Invest. 2004 Feb;34(2):100-6.
Title:	K-ras and B-raf gene mutations are not associated with gastrin- and CCK2-receptor mRNA expression in human colorectal tumour tissues.
Author:	Monstein, H-J\|Fransen, K\|Dimberg, J\|Soderkvist, P
PMID:	14764072

365.
Journal:	Int J Oncol. 2004 Mar;24(3):687-96.
Title:	Quantitative detection of mutant alleles of the K-ras gene with minor groove binder-conjugated fluorogenic DNA probes.
Author:	Itabashi, Tetsuya\|Maesawa, Cihaya\|Uchiyama, Michiro\|Higuchi, Taro\|Masuda, Tomoyuki
PMID:	14767554

366.
Journal:	J Pathol. 2004 Mar;202(3):336-40.
Title:	In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours.
Author:	Sieben, Nathalie L G\|Macropoulos, Patricia\|Roemen, Guido M J M\|Kolkman-Uljee, Sandra M\|Jan Fleuren, Gert\|Houmadi, Rifat\|Diss, Tim\|Warren, Bretta\|Al Adnani, Mudher\|De Goeij, Anton P M\|Krausz, Thomas\|Flanagan, Adrienne M
PMID:	14991899

367.
Journal:	Cancer Res. 2004 Mar 1;64(5):1765-72.
Title:	Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.
Author:	Mizukami, Yusuke\|Li, Jingnan\|Zhang, Xiaobo\|Zimmer, Michael A\|Iliopoulos, Othon\|Chung, Daniel C
PMID:	14996738

368.
Journal:	Genes Chromosomes Cancer. 2004 May;40(1):1-9.
Title:	Role of inherited defects of MYH in the development of sporadic colorectal cancer.
Author:	Kambara, Takeshi\|Whitehall, Vicki L J\|Spring, Kevin J\|Barker, Melissa A\|Arnold, Sven\|Wynter, Coral V A\|Matsubara, Nagahide\|Tanaka, Noriaki\|Young, Joanne P\|Leggett, Barbara A\|Jass, Jeremy R
PMID:	15034862

369.
Journal:	Nucleic Acids Res. 2004 Mar 22;32(5):e53.
Title:	Sensitive and specific detection of K-ras mutations in colon tumors by short oligonucleotide mass analysis.
Author:	Lleonart, Matilde E\|Ramon y Cajal, Santiago\|Groopman, John D\|Friesen, Marlin D
PMID:	15037663

370.
Journal:	Int J Cancer. 2004 Jun 10;110(2):183-7.
Title:	Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer.
Author:	Ferraz, Jean-Marc\|Zinzindohoue, Franck\|Lecomte, Thierry\|Cugnenc, Paul-Henri\|Loriot, Marie-Anne\|Beaune, Philippe\|Stucker, Isabelle\|Berger, Anne\|Laurent-Puig, Pierre
PMID:	15069679

371.
Journal:	J Mol Diagn. 2004 May;6(2):101-7.
Title:	Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer.
Author:	Su, Ying-Hsiu\|Wang, Mengjun\|Brenner, Dean E\|Ng, Alan\|Melkonyan, Hovsep\|Umansky, Samuil\|Syngal, Sapna\|Block, Timothy M
PMID:	15096565

372.
Journal:	Carcinogenesis. 2004 Sep;25(9):1619-28. Epub 2004 Apr 29.
Title:	Fat and K-ras mutations in sporadic colorectal cancer in The Netherlands Cohort Study.
Author:	Brink, Mirian\|Weijenberg, Matty P\|De Goeij, Anton F P M\|Schouten, Leo J\|Koedijk, Femke D H\|Roemen, Guido M J M\|Lentjes, Marjolein H F M\|De Bruine, Adriaan P\|Goldbohm, R Alexandra\|Van Den Brandt, Piet A
PMID:	15117813

373.
Journal:	Am J Obstet Gynecol. 2004 Apr;190(4):935-42.
Title:	RAS/RAF mutation and defective DNA mismatch repair in endometrial cancers.
Author:	Mutch, David G\|Powell, Matthew A\|Mallon, Mary Ann\|Goodfellow, Paul J
PMID:	15118616

374.
Journal:	Int J Oncol. 2004 Jun;24(6):1537-44.
Title:	K-ras codon 12 and 13 mutations are correlated with differential patterns of tumor cell dissemination in colorectal cancer patients.
Author:	Conzelmann, Michael\|Linnemann, Ulrich\|Berger, Martin R
PMID:	15138598

375.
Journal:	Cancer Lett. 2004 Jul 8;210(1):101-9.
Title:	p53 is an independent pre-treatment markers for long-term survival in stage II and III colorectal cancers: an analysis of interaction between genetic markers and fluorouracil-based adjuvant therapy.
Author:	Tang, Reiping\|Wang, Jeng-Yi\|Fan, Chung-Wei\|Tsao, Kuo-Chien\|Chen, Hong-Hua\|Wu, Chi-Ming\|Chen, Jinn-Shiun\|Changchien, Chung Rong\|Hsieh, Ling-Ling
PMID:	15172127

376.
Journal:	Cancer Lett. 2004 Jul 28;211(1):105-9.
Title:	Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer.
Author:	Miyaki, Michiko\|Iijima, Takeru\|Yamaguchi, Tatsuro\|Kadofuku, Tsuyoki\|Funata, Nobuaki\|Mori, Takeo
PMID:	15194222

377.
Journal:	Br J Cancer. 2004 Jul 19;91(2):312-8.
Title:	Pathological features and genetic alterations in colorectal carcinomas with characteristics of nonpolypoid growth.
Author:	Kaneko, K\|Kurahashi, T\|Makino, R\|Konishi, K\|Ito, H\|Katagiri, A\|Kumekawa, Y\|Hirayama, Y\|Yoneyama, K\|Kushima, M\|Kusano, M\|Tajiri, H\|Rembacken, B J\|Mitamura, K\|Imawari, M
PMID:	15213719

378.
Journal:	J Gastroenterol. 2004 Jun;39(6):544-9.
Title:	Analysis of Ki-ras gene mutations within the same tumor using a single tumor crypt in colorectal carcinomas.
Author:	Ishii, Motohiro\|Sugai, Tamotsu\|Habano, Wataru\|Nakamura, Shin-Ichi
PMID:	15235871

379.
Journal:	Anticancer Res. 2004 May-Jun;24(3b):2011-20.
Title:	Decrease in specific micronutrient intake in colorectal cancer patients with tumors presenting Ki-ras mutation.
Author:	Laso, Nuria\|Mas, Sergi\|Jose Lafuente, M\|Casterad, Xavier\|Trias, Manuel\|Ballesta, Antonio\|Molina, Rafael\|Salas, Jordi\|Ascaso, Carlos\|Zheng, Shichun\|Wiencke, John K\|Lafuente, Amalia
PMID:	15274393

380.
Journal:	Hum Mol Genet. 2004 Oct 1;13(19):2303-11. Epub 2004 Aug 4.
Title:	Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
Author:	Oliveira, Carla\|Westra, Jantine L\|Arango, Diego\|Ollikainen, Miina\|Domingo, Enric\|Ferreira, Ana\|Velho, Sergia\|Niessen, Renee\|Lagerstedt, Kristina\|Alhopuro, Pia\|Laiho, Paivi\|Veiga, Isabel\|Teixeira, Manuel R\|Ligtenberg, Marjolijn\|Kleibeuker, Jan H\|Sijmons, R
PMID:	15294875

381.
Journal:	Anticancer Res. 2004 Jul-Aug;24(4):2471-6.
Title:	Association of K-ras mutations with liver metastases from colorectal carcinoma.
Author:	Tsunoda, Akira\|Iijima, Takeru\|Tsunoda, Yuko\|Nakao, Kentaroh\|Miyaki, Michiko\|Kusano, Mitsuo
PMID:	15330200

382.
Journal:	J Clin Pathol. 2004 Sep;57(9):938-42.
Title:	Ki-ras gene mutations, LOH of the APC and DCC genes, and microsatellite instability in primary colorectal carcinoma are not associated with micrometastases in pericolonic lymph nodes or with patients' survival.
Author:	Zauber, N P\|Wang, C\|Lee, P S\|Redondo, T C\|Bishop, D T\|Goel, A
PMID:	15333653

383.
Journal:	Mol Cancer. 2004 Oct 11;3:28.
Title:	A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.
Author:	Lind, Guro E\|Thorstensen, Lin\|Lovig, Tone\|Meling, Gunn I\|Hamelin, Richard\|Rognum, Torleiv O\|Esteller, Manel\|Lothe, Ragnhild A
PMID:	15476557

384.
Journal:	Am J Surg Pathol. 2004 Nov;28(11):1452-9.
Title:	BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.
Author:	Yang, Shi\|Farraye, Francis A\|Mack, Charline\|Posnik, Oksana\|O'Brien, Michael J
PMID:	15489648

385.
Journal:	Scand J Gastroenterol. 2004 Aug;39(8):748-53.
Title:	Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomas.
Author:	Blaker, H\|Helmchen, B\|Bonisch, A\|Aulmann, S\|Penzel, R\|Otto, H F\|Rieker, R J
PMID:	15513360

386.
Journal:	World J Gastroenterol. 2004 Dec 15;10(24):3688-90.
Title:	Co-mutation of p53, K-ras genes and accumulation of p53 protein and its correlation to clinicopathological features in rectal cancer.
Author:	Pan, Zhi-Zhong\|Wan, De-Sen\|Chen, Gong\|Li, Li-Ren\|Lu, Zhen-Hai\|Huang, Bi-Jun
PMID:	15534934

387.
Journal:	Appl Immunohistochem Mol Morphol. 2004 Dec;12(4):380-6.
Title:	p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochemistry.
Author:	Curtin, Karen\|Slattery, Martha L\|Holubkov, Richard\|Edwards, Sandra\|Holden, Joseph A\|Samowitz, Wade S
PMID:	15536342

388.
Journal:	Biochem Biophys Res Commun. 2004 Dec 17;325(3):784-91.
Title:	Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations.
Author:	Albanese, Ida\|Scibetta, Angelo Giuseppe\|Migliavacca, Manuela\|Russo, Antonio\|Bazan, Viviana\|Tomasino, Rosa Maria\|Colomba, Paolo\|Tagliavia, Marcello\|La Farina, Mario
PMID:	15541358

389.
Journal:	Mutat Res. 2004 Dec 21;568(2):283-92.
Title:	Genomic heterogeneity and instability in colorectal cancer: spectral karyotyping, glutathione transferase-Ml and ras.
Author:	Bartos, Jeremy D\|Stoler, Daniel L\|Matsui, Sei-ichi\|Swede, Helen\|Willmott, Lyndsay J\|Sait, Sheila N\|Petrelli, Nicholas J\|Anderson, Garth R
PMID:	15542115

390.
Journal:	J Clin Oncol. 2004 Nov 15;22(22):4584-94.
Title:	Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Author:	Nagasaka, Takeshi\|Sasamoto, Hiromi\|Notohara, Kenji\|Cullings, Harry M\|Takeda, Masanori\|Kimura, Keigo\|Kambara, Takeshi\|MacPhee, Donald G\|Young, Joanne\|Leggett, Barbara A\|Jass, Jeremy R\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	15542810

391.
Journal:	Clin Colorectal Cancer. 2004 Nov;4(4):252-9.
Title:	Genetic alterations in locally advanced stage II/III colon cancer: a search for prognostic markers.
Author:	Westra, Jantine L\|Plukker, John T\|Buys, Charles H\|Hofstra, Robert M
PMID:	15555207

392.
Journal:	Dig Dis Sci. 2004 Oct;49(10):1631-3.
Title:	Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis.
Author:	Shitoh, Kazuhisa\|Koinuma, Koji\|Furukawa, Taiji\|Okada, Masaki\|Nagai, Hideo
PMID:	15573917

393.
Journal:	Dis Colon Rectum. 2004 Nov;47(11):1915-21.
Title:	Cyclooxygenase-2 overexpression is related to polypoid growth and K-ras gene mutation in T1 colorectal carcinomas.
Author:	Okawa, Takuya\|Yoshinaga, Keigo\|Uetake, Hiroyuki\|Sato, Takanobu\|Higuchi, Tetsuro\|Nemoto, Tetsuo\|Sugihara, Kenichi
PMID:	15622585

394.
Journal:	Rocz Akad Med Bialymst. 2004;49 Suppl 1:52-4.
Title:	Clinical usefulness of K-RAS mutation detection in colorectal cancer and in surgical margins of the colon.
Author:	Okulczyk, B\|Kovalchuk, O\|Piotrowski, Z\|Mysliwiec, P\|Chyczewski, L
PMID:	15638373

395.
Journal:	J Cell Physiol. 2005 Feb;202(2):503-9.
Title:	Laser pressure catapulting (LPC): optimization LPC-system and genotyping of colorectal carcinomas.
Author:	Bazan, Viviana\|La Rocca, Gaspare\|Corsale, Simona\|Agnese, Valentina\|Macaluso, Marcella\|Migliavacca, Manuela\|Gregorio, Valter\|Cascio, Sandra\|Sisto, Pasqua Sandra\|Di Fede, Gaetana\|Buscemi, Maria\|Fiorentino, Eugenio\|Passantino, Rita\|Morello, Vincenza\|Tomasino
PMID:	15316933

396.
Journal:	Blood. 2005 Feb 15;105(4):1734-41. Epub 2004 Oct 19.
Title:	Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis.
Author:	Yu, Joanne L\|May, Linda\|Lhotak, Vladimir\|Shahrzad, Siranoush\|Shirasawa, Senji\|Weitz, Jeffrey I\|Coomber, Brenda L\|Mackman, Nigel\|Rak, Janusz W
PMID:	15494427

397.
Journal:	J Cancer Res Clin Oncol. 2005 Feb;131(2):101-10.
Title:	Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells.
Author:	Kapitza, S\|Pongratz, M\|Jakupec, M A\|Heffeter, P\|Berger, W\|Lackinger, L\|Keppler, B K\|Marian, B
PMID:	15503135

398.
Journal:	Int J Cancer. 2005 May 1;114(5):824-30.
Title:	Dietary folate intake and k-ras mutations in sporadic colon and rectal cancer in The Netherlands Cohort Study.
Author:	Brink, Mirian\|Weijenberg, Matty P\|de Goeij, Anton F P M\|Roemen, Guido M J M\|Lentjes, Marjolein H F M\|de Bruine, Adriaan P\|van Engeland, Manon\|Goldbohm, R Alexandra\|van den Brandt, Piet A
PMID:	15609319

399.
Journal:	Clin Cancer Res. 2005 Jan 1;11(1):41-8.
Title:	Cyclooxygenase-2 is a target of KRASD12, which facilitates the outgrowth of murine C26 colorectal liver metastases.
Author:	Smakman, Niels\|Kranenburg, Onno\|Vogten, Jan M\|Bloemendaal, Alexander L A\|van Diest, Paul\|Borel Rinkes, Inne H M
PMID:	15671526

400.
Journal:	J Cell Physiol. 2005 Aug;204(2):484-8.
Title:	Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression.
Author:	Calistri, Daniele\|Rengucci, Claudia\|Seymour, Ian\|Lattuneddu, Arturo\|Polifemo, Anna Maria\|Monti, Franco\|Saragoni, Luca\|Amadori, Dino
PMID:	15702478

401.
Journal:	Int J Cancer. 2005 Jul 10;115(5):673-7.
Title:	Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma.
Author:	Aust, Daniela E\|Haase, Michael\|Dobryden, Lyudmyla\|Markwarth, Annett\|Lohrs, Udo\|Wittekind, Christian\|Baretton, Gustavo B\|Tannapfel, Andrea
PMID:	15704157

402.
Journal:	Oncol Rep. 2005 Mar;13(3):473-6.
Title:	Mapping of the critical region of mitogene-inducible gene-6 for NF-kappaB activation.
Author:	Mabuchi, Reiko\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	15706420

403.
Journal:	Genes Chromosomes Cancer. 2005 Jun;43(2):194-201.
Title:	A substantial proportion of microsatellite-unstable colon tumors carry TP53 mutations while not showing chromosomal instability.
Author:	Westra, Jantine L\|Boven, Ludolf G\|van der Vlies, Pieter\|Faber, Hendrika\|Sikkema, Birgit\|Schaapveld, Michael\|Dijkhuizen, Trijnie\|Hollema, Harry\|Buys, Charles H C M\|Plukker, John T M\|Kok, Klaas\|Hofstra, Robert M W
PMID:	15729700

404.
Journal:	Int J Cancer. 2005 Jul 20;115(6):943-50.
Title:	BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms.
Author:	Ikehara, Nobunao\|Semba, Shuho\|Sakashita, Masanori\|Aoyama, Nobuo\|Kasuga, Masato\|Yokozaki, Hiroshi
PMID:	15729718

405.
Journal:	Cancer Res. 2005 Feb 15;65(4):1244-50.
Title:	Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.
Author:	Pollock, Claire B\|Shirasawa, Senji\|Sasazuki, Takehiko\|Kolch, Walter\|Dhillon, Amardeep S
PMID:	15735008

406.
Journal:	Cancer Res. 2005 Mar 1;65(5):1642-6.
Title:	Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
Author:	Shigematsu, Hisayuki\|Takahashi, Takao\|Nomura, Masaharu\|Majmudar, Kuntal\|Suzuki, Makoto\|Lee, Huei\|Wistuba, Ignacio I\|Fong, Kwun M\|Toyooka, Shinichi\|Shimizu, Nobuyoshi\|Fujisawa, Takehiko\|Minna, John D\|Gazdar, Adi F
PMID:	15753357

407.
Journal:	Cancer Genet Cytogenet. 2005 Apr 1;158(1):55-60.
Title:	Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan.
Author:	Wu, Chi-Ming\|Tang, Reiping\|Wang, Jeng-Yi\|Changchien, Chung-Rong\|Hsieh, Ling-Ling
PMID:	15771905

408.
Journal:	Cancer Res. 2005 Mar 15;65(6):2085-8.
Title:	Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells.
Author:	Stearns, Mark\|Tran, Jordan\|Francis, Mary Kay\|Zhang, Hong\|Sell, Christian
PMID:	15781617

409.
Journal:	Cancer Res. 2005 Mar 15;65(6):2321-9.
Title:	Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.
Author:	Dalerba, Piero\|Guiducci, Cristiana\|Poliani, Pietro Luigi\|Cifola, Ingrid\|Parenza, Mariella\|Frattini, Milo\|Gallino, Gianfrancesco\|Carnevali, Ileana\|Di Giulio, Ilvia\|Andreola, Salvatore\|Lombardo, Claudia\|Rivoltini, Licia\|Schweighoffer, Tamas\|Belli, Filiberto
PMID:	15781646

410.
Journal:	Anticancer Res. 2005 Jan-Feb;25(1B):657-61.
Title:	Persistence of K-ras mutations in plasma after colorectal tumor resection.
Author:	Lindforss, Ulrik\|Zetterquist, Henrik\|Papadogiannakis, Nikos\|Olivecrona, Hans
PMID:	15816642

411.
Journal:	Lancet Oncol. 2005 May;6(5):279-86.
Title:	Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study.
Author:	Moroni, Mauro\|Veronese, Silvio\|Benvenuti, Silvia\|Marrapese, Giovanna\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Gambacorta, Marcello\|Siena, Salvatore\|Bardelli, Alberto
PMID:	15863375

412.
Journal:	Ann Oncol. 2005 May;16 Suppl 4:iv44-49.
Title:	Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies.
Author:	Russo, A\|Bazan, V\|Agnese, V\|Rodolico, V\|Gebbia, N
PMID:	15923428

413.
Journal:	Ann Oncol. 2005 May;16 Suppl 4:iv50-55.
Title:	Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study.
Author:	Bazan, V\|Agnese, V\|Corsale, S\|Calo, V\|Valerio, M R\|Latteri, M A\|Vieni, S\|Grassi, N\|Cicero, G\|Dardanoni, G\|Tomasino, R M\|Colucci, G\|Gebbia, N\|Russo, A
PMID:	15923430

414.
Journal:	Colorectal Dis. 2005 Jul;7(4):323-6.
Title:	Colorectal adenomas with a low frequency of ki-ras mutations: a sample from a population with a low mortality rate from colorectal cancer.
Author:	Kornaros, S\|Liloglou, T\|Politou, M\|Elemenoglou, I
PMID:	15932552

415.
Journal:	Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title:	Molecular markers that predict response to colon cancer therapy.
Author:	Ahmed, Farid E
PMID:	15934813

416.
Journal:	Gastroenterology. 2005 Jun;128(7):1907-18.
Title:	Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta.
Author:	Li, Jingnan\|Mizukami, Yusuke\|Zhang, Xiaobo\|Jo, Won-Seok\|Chung, Daniel C
PMID:	15940626

417.
Journal:	Cancer. 2005 Aug 15;104(4):719-29.
Title:	Clinical and genetic findings in an Ashkenazi Jewish population with colorectal neoplasms.
Author:	Zauber, N Peter\|Sabbath-Solitare, Marlene\|Marotta, Stephen\|Zauber, Ann G\|Foulkes, William\|Chan, May\|Turner, Faye\|Bishop, D Timothy
PMID:	15959913

418.
Journal:	Eur J Cancer. 2005 Jul;41(11):1649-54.
Title:	The prevalence of PIK3CA mutations in gastric and colon cancer.
Author:	Velho, Sergia\|Oliveira, Carla\|Ferreira, Ana\|Ferreira, Antonio Carlos\|Suriano, Gianpaolo\|Schwartz, Simo Jr\|Duval, Alex\|Carneiro, Fatima\|Machado, Jose Carlos\|Hamelin, Richard\|Seruca, Raquel
PMID:	15994075

419.
Journal:	Oncogene. 2005 Nov 17;24(51):7630-4.
Title:	Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
Author:	Oliveira, Carla\|Velho, Sergia\|Domingo, Enric\|Preto, Ana\|Hofstra, Robert M W\|Hamelin, Richard\|Yamamoto, Hiroyuki\|Seruca, Raquel\|Schwartz, Simo Jr
PMID:	16007118

420.
Journal:	Gastroenterology. 2005 Jul;129(1):156-69.
Title:	The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.
Author:	Akino, Kimishige\|Toyota, Minoru\|Suzuki, Hiromu\|Mita, Hiroaki\|Sasaki, Yasushi\|Ohe-Toyota, Mutsumi\|Issa, Jean-Pierre J\|Hinoda, Yuji\|Imai, Kohzoh\|Tokino, Takashi
PMID:	16012945

421.
Journal:	Cancer. 2005 Sep 1;104(5):952-61.
Title:	BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
Author:	Lubomierski, Nikolaus\|Plotz, Guido\|Wormek, Marc\|Engels, Knut\|Kriener, Susanne\|Trojan, Jorg\|Jungling, Bernd\|Zeuzem, Stefan\|Raedle, Jochen
PMID:	16015629

422.
Journal:	Electrophoresis. 2005 Aug;26(16):3076-80.
Title:	Detection of single-base mutation by affinity capillary electrophoresis using a DNA-polyacrylamide conjugate.
Author:	Sato, Kae\|Inoue, Akira\|Hosokawa, Kazuo\|Maeda, Mizuo
PMID:	16041699

423.
Journal:	Biochem Soc Trans. 2005 Aug;33(Pt 4):679-83.
Title:	MutYH (MYH) and colorectal cancer.
Author:	Sampson, J R\|Jones, S\|Dolwani, S\|Cheadle, J P
PMID:	16042573

424.
Journal:	J Mol Diagn. 2005 Aug;7(3):413-21.
Title:	Sensitive sequencing method for KRAS mutation detection by Pyrosequencing.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Brahmandam, Mohan\|Yan, Liying\|Cantor, Mami\|Namgyal, Chungdak\|Mino-Kenudson, Mari\|Lauwers, Gregory Y\|Loda, Massimo\|Fuchs, Charles S
PMID:	16049314

425.
Journal:	Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 May;19(9):417-9.
Title:	[The expressions of K-ras in human laryngeal squamous cell carcinoma cell lines (Hep-2) and its significance].
Author:	Chen, Xiong\|Kong, Weijia\|Cai, Guanglian\|Zhang, Sulin\|Zhang, Dan
PMID:	16075979

426.
Journal:	Oncol Rep. 2005 Sep;14(3):625-31.
Title:	Mutations in the p53 and Ki-ras genes, microsatellite instability and site of tumor origin in colorectal cancer.
Author:	Catalano, Teresa\|Curia, Maria Cristina\|Aceto, Gitana\|Verginelli, Fabio\|Cascinu, Stefano\|Cama, Alessandro\|Mariani-Costantini, Renato\|Teti, Diana\|Battista, Pasquale
PMID:	16077965

427.
Journal:	Oncogene. 2005 Dec 15;24(56):8338-42.
Title:	Dual effect of Kras(D12) knockdown on tumorigenesis: increased immune-mediated tumor clearance and abrogation of tumor malignancy.
Author:	Smakman, Niels\|Veenendaal, Liesbeth M\|van Diest, Paul\|Bos, Rinke\|Offringa, Rienk\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	16091732

428.
Journal:	Biochim Biophys Acta. 2005 Nov 25;1756(2):103-14.
Title:	Control of colorectal metastasis formation by K-Ras.
Author:	Smakman, Niels\|Borel Rinkes, Inne H M\|Voest, Emile E\|Kranenburg, Onno
PMID:	16098678

429.
Journal:	J Clin Oncol. 2005 Aug 20;23(24):5635-43.
Title:	Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients.
Author:	Westra, Jantine L\|Schaapveld, Michael\|Hollema, Harry\|de Boer, Jelle P\|Kraak, Marian M J\|de Jong, Debora\|ter Elst, Arja\|Mulder, Nanno H\|Buys, Charles H C M\|Hofstra, Robert M W\|Plukker, John T M
PMID:	16110022

430.
Journal:	Biochim Biophys Acta. 2005 Nov 25;1756(2):115-25. Epub 2005 Jul 13.
Title:	Mutant KRAS, chromosomal instability and prognosis in colorectal cancer.
Author:	Castagnola, Patrizio\|Giaretti, Walter
PMID:	16112461

431.
Journal:	Nat Med. 2005 Sep;11(9):992-7. Epub 2005 Aug 28.
Title:	Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.
Author:	Mizukami, Yusuke\|Jo, Won-Seok\|Duerr, Eva-Maria\|Gala, Manish\|Li, Jingnan\|Zhang, Xiaobo\|Zimmer, Michael A\|Iliopoulos, Othon\|Zukerberg, Lawrence R\|Kohgo, Yutaka\|Lynch, Maureen P\|Rueda, Bo R\|Chung, Daniel C
PMID:	16127434

432.
Journal:	Gastroenterology. 2005 Sep;129(3):837-45.
Title:	Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer.
Author:	Samowitz, Wade S\|Albertsen, Hans\|Herrick, Jennifer\|Levin, Theodore R\|Sweeney, Carol\|Murtaugh, Maureen A\|Wolff, Roger K\|Slattery, Martha L
PMID:	16143123

433.
Journal:	Cancer Res. 2005 Sep 15;65(18):8134-41.
Title:	Ischemia-induced K-ras mutations in human colorectal cancer cells: role of microenvironmental regulation of MSH2 expression.
Author:	Shahrzad, Siranoush\|Quayle, Lindsay\|Stone, Courtney\|Plumb, Claire\|Shirasawa, Senji\|Rak, Janusz W\|Coomber, Brenda L
PMID:	16166287

434.
Journal:	Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
Title:	Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Cantor, Mami\|Brahmandam, Mohan\|Clark, Jeffrey W\|Namgyal, Chungdak\|Kawasaki, Takako\|Kinsella, Kate\|Michelini, Ann L\|Enzinger, Peter C\|Kulke, Matthew H\|Ryan, David P\|Loda, Massimo\|Fuchs, Charles S
PMID:	16166444

435.
Journal:	J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8.
Title:	MGMT promoter methylation and field defect in sporadic colorectal cancer.
Author:	Shen, Lanlan\|Kondo, Yutaka\|Rosner, Gary L\|Xiao, Lianchun\|Hernandez, Natalie Supunpong\|Vilaythong, Jill\|Houlihan, P Scott\|Krouse, Robert S\|Prasad, Anil R\|Einspahr, Janine G\|Buckmeier, Julie\|Alberts, David S\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	16174854

436.
Journal:	J Nutr. 2005 Oct;135(10):2462-7.
Title:	MTHFR variants reduce the risk of G:C->A:T transition mutations within the p53 tumor suppressor gene in colon tumors.
Author:	Ulrich, C M\|Curtin, K\|Samowitz, W\|Bigler, J\|Potter, J D\|Caan, B\|Slattery, M L
PMID:	16177213

437.
Journal:	Hepatogastroenterology. 2005 Sep-Oct;52(65):1421-6.
Title:	Venous invasion and down-regulation of p21(WAF1/CIP1) are associated with metastasis in colorectal carcinomas.
Author:	Mitomi, Hiroyuki\|Mori, Akio\|Kanazawa, Hideki\|Nishiyama, Yasuhiko\|Ihara, Atsushi\|Otani, Yoshimasa\|Sada, Miwa\|Kobayashi, Kiyonori\|Igarashi, Masahiro
PMID:	16201087

438.
Journal:	Cancer Biol Ther. 2005 Aug;4(8):861-3.
Title:	The Cables gene on chromosome 18Q regulates colon cancer progression in vivo.
Author:	Kirley, Sandra D\|D'Apuzzo, Massimo\|Lauwers, Gregory Y\|Graeme-Cook, Fiona\|Chung, Daniel C\|Zukerberg, Lawrence R
PMID:	16210915

439.
Journal:	Biochim Biophys Acta. 2005 Nov 25;1756(2):83-96. Epub 2005 Jul 18.
Title:	Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer?
Author:	Pretlow, Theresa P\|Pretlow, Thomas G
PMID:	16219426

440.
Journal:	Rev Esp Enferm Dig. 2005 Jul;97(7):472-80.
Title:	Antisense gene therapy using anti-k-ras and antitelomerase oligonucleotides in colorectal cancer.
Author:	Lledo, S\|Alfonso, R\|Alino, S F
PMID:	16262526

441.
Journal:	J Virol. 2005 Dec;79(23):14981-5.
Title:	Sensitization to apoptosis underlies KrasD12-dependent oncolysis of murine C26 colorectal carcinoma cells by reovirus T3D.
Author:	Smakman, Niels\|van den Wollenberg, Diana J M\|Borel Rinkes, Inne H M\|Hoeben, Rob C\|Kranenburg, Onno
PMID:	16282499

442.
Journal:	Clin Cancer Res. 2005 Dec 1;11(23):8281-7.
Title:	Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries.
Author:	Chan, Annie O\|Soliman, Amr S\|Zhang, Qing\|Rashid, Asif\|Bedeir, Ahmed\|Houlihan, P Scott\|Mokhtar, Nadia\|Al-Masri, Nidal\|Ozbek, Ugur\|Yaghan, Rami\|Kandilci, Ayten\|Omar, Sherif\|Kapran, Yersu\|Dizdaroglu, Ferhunde\|Bondy, Melissa L\|Amos, Christopher I\|Issa, Jean-P
PMID:	16322286

443.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Dec;22(6):694-7.
Title:	[Loss of heterozygosity on chromosome 12p12-13 region in Chinese patients with colon carcinoma].
Author:	Li, Hong\|Wan, Jun\|Li, Yuan\|Zhu, Mei-ling\|Zhao, Po
PMID:	16331576

444.
Journal:	BMC Cancer. 2005 Dec 15;5:160.
Title:	Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.
Author:	Luchtenborg, Margreet\|Weijenberg, Matty P\|Wark, Petra A\|Saritas, A Merdan\|Roemen, Guido M J M\|van Muijen, Goos N P\|de Bruine, Adriaan P\|van den Brandt, Piet A\|de Goeij, Anton F P M
PMID:	16356174

445.
Journal:	Biomed Pharmacother. 2005 Oct;59 Suppl 2:S370-4.
Title:	Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathway.
Author:	Dvory-Sobol, H\|Kazanov, D\|Arber, N
PMID:	16507412

446.
Journal:	Cancer Biomark. 2005;1(2-3):177-82.
Title:	Detection of a K-ras mutation in urine of patients with colorectal cancer.
Author:	Su, Ying-Hsiu\|Wang, Mengjun\|Aiamkitsumrit, Benjamas\|Brenner, Dean E\|Block, Timothy M
PMID:	17192038

447.
Journal:	Mod Pathol. 2006 Jan;19(1):59-68.
Title:	Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Cantor, Mami\|Namgyal, Chungdak\|Kawasaki, Takako\|Kirkner, Gregory\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Fuchs, Charles S
PMID:	16118624

448.
Journal:	Int J Cancer. 2006 Feb 1;118(3):616-27.
Title:	Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.
Author:	Roberts, Michael L\|Drosopoulos, Konstantinos G\|Vasileiou, Ioannis\|Stricker, Mona\|Taoufik, Era\|Maercker, Christian\|Guialis, Apostolia\|Alexis, Michael N\|Pintzas, Alexander
PMID:	16152623

449.
Journal:	Oncogene. 2006 Jan 5;25(1):91-102.
Title:	Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer.
Author:	Seiden-Long, I M\|Brown, K R\|Shih, W\|Wigle, D A\|Radulovich, N\|Jurisica, I\|Tsao, M-S
PMID:	16158056

450.
Journal:	Int J Cancer. 2006 Apr 1;118(7):1721-7.
Title:	Relationship between genetic alterations and prognosis in sporadic colorectal cancer.
Author:	Chang, Shih-Ching\|Lin, Jen-Kou\|Yang, Shung Haur\|Wang, Huann-Sheng\|Li, Anna Fen-Yau\|Chi, Chin-Wen
PMID:	16231316

451.
Journal:	Biochem Biophys Res Commun. 2006 Feb 10;340(2):469-75. Epub 2005 Dec 15.
Title:	Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines.
Author:	Whyte, David B\|Holbeck, Susan L
PMID:	16376301

452.
Journal:	Int J Cancer. 2006 Jun 1;118(11):2765-71.
Title:	BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer.
Author:	Tanaka, Hirofumi\|Deng, Guoren\|Matsuzaki, Koji\|Kakar, Sanjay\|Kim, Grace E\|Miura, Soichiro\|Sleisenger, Marvin H\|Kim, Young S
PMID:	16381005

453.
Journal:	Mol Cancer. 2006 Jan 10;5:2.
Title:	BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status.
Author:	Li, Wei Qi\|Kawakami, Kazuyuki\|Ruszkiewicz, Andrew\|Bennett, Graeme\|Moore, James\|Iacopetta, Barry
PMID:	16403224

454.
Journal:	Gut. 2006 Jul;55(7):1000-6. Epub 2006 Jan 11.
Title:	CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Author:	Ogino, S\|Cantor, M\|Kawasaki, T\|Brahmandam, M\|Kirkner, G J\|Weisenberger, D J\|Campan, M\|Laird, P W\|Loda, M\|Fuchs, C S
PMID:	16407376

455.
Journal:	Mutat Res. 2006 Mar 20;595(1-2):117-24.
Title:	Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer.
Author:	Samowitz, Wade S\|Wolff, Roger K\|Ma, Khe Ni\|Andersen, Kristen\|Caan, Bette\|Slattery, Martha L
PMID:	16448675

456.
Journal:	Anticancer Res. 2006 Jan-Feb;26(1A):107-19.
Title:	Aberrant crypt foci.
Author:	Alrawi, Sadir J\|Schiff, Michael\|Carroll, Robert E\|Dayton, Merril\|Gibbs, John F\|Kulavlat, Mahmood\|Tan, Dongfeng\|Berman, Kevin\|Stoler, Daniel L\|Anderson, Garth R
PMID:	16475686

457.
Journal:	Cancer Causes Control. 2006 Apr;17(3):239-49.
Title:	PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).
Author:	Slattery, Martha L\|Curtin, Karen\|Wolff, Roger\|Ma, Khe Ni\|Sweeney, Carol\|Murtaugh, Maureen\|Potter, John D\|Levin, Theodore R\|Samowitz, Wade
PMID:	16489531

458.
Journal:	Mol Cancer Ther. 2006 Feb;5(2):309-16.
Title:	RRR-alpha-tocopherol succinate down-regulates oncogenic Ras signaling.
Author:	Donapaty, Sreenivasa\|Louis, Somaja\|Horvath, Elizabeth\|Kun, Jiang\|Sebti, Said M\|Malafa, Mokenge P
PMID:	16505104

459.
Journal:	World J Gastroenterol. 2006 Feb 21;12(7):1033-7.
Title:	Loss of heterozygosity of Kras2 gene on 12p12-13 in Chinese colon carcinoma patients.
Author:	Wan, Jun\|Li, Hong\|Li, Yuan\|Zhu, Mei-Ling\|Zhao, Po
PMID:	16534842

460.
Journal:	Cancer Gene Ther. 2006 Aug;13(8):815-8.
Title:	Immunosuppression promotes reovirus therapy of colorectal liver metastases.
Author:	Smakman, N\|van der Bilt, J D W\|van den Wollenberg, D J M\|Hoeben, R C\|Borel Rinkes, I H M\|Kranenburg, O
PMID:	16543920

461.
Journal:	Cancer Res. 2006 Apr 15;66(8):3992-5.
Title:	KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.
Author:	Lievre, Astrid\|Bachet, Jean-Baptiste\|Le Corre, Delphine\|Boige, Valerie\|Landi, Bruno\|Emile, Jean-Francois\|Cote, Jean-Francois\|Tomasic, Gorana\|Penna, Christophe\|Ducreux, Michel\|Rougier, Philippe\|Penault-Llorca, Frederique\|Laurent-Puig, Pierre
PMID:	16618717

462.
Journal:	Anticancer Res. 2006 Mar-Apr;26(2A):1077-84.
Title:	Cancer genetics of sporadic colorectal cancer: BRAF and PI3KCA mutations, their impact on signaling and novel targeted therapies.
Author:	Oikonomou, Eftychia\|Pintzas, Alexandros
PMID:	16619509

463.
Journal:	J Mol Diagn. 2006 May;8(2):193-201.
Title:	Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas.
Author:	Sugai, Tamotsu\|Habano, Wataru\|Jiao, Yu-Fei\|Tsukahara, Mitsunori\|Takeda, Yuichiro\|Otsuka, Koki\|Nakamura, Shin-ichi
PMID:	16645205

464.
Journal:	BMC Cancer. 2006 May 4;6:115.
Title:	Coexistence of K-ras mutations and HPV infection in colon cancer.
Author:	Buyru, Nur\|Tezol, Ayda\|Dalay, Nejat
PMID:	16672071

465.
Journal:	Mod Pathol. 2006 Aug;19(8):1083-90.
Title:	Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Author:	Ogino, Shuji\|Brahmandam, Mohan\|Kawasaki, Takako\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	16699497

466.
Journal:	Cancer Res. 2006 May 15;66(10):5403-8.
Title:	KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand.
Author:	Smakman, Niels\|van den Wollenberg, Diana J M\|Elias, Sjoerd G\|Sasazuki, Takehiko\|Shirasawa, Senji\|Hoeben, Rob C\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	16707468

467.
Journal:	Ann Oncol. 2006 Jun;17 Suppl 7:vii84-90.
Title:	Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
Author:	Bazan, V\|Bruno, L\|Augello, C\|Agnese, V\|Calo, V\|Corsale, S\|Gargano, G\|Terrasi, M\|Schiro, V\|Di Fede, G\|Adamo, V\|Intrivici, C\|Crosta, A\|Rinaldi, G\|Latteri, F\|Dardanoni, G\|Grassi, N\|Valerio, M R\|Colucci, G\|Macaluso, M\|Russo, A
PMID:	16760301

468.
Journal:	Toxicol Sci. 2006 Oct;93(2):286-97.
Title:	Uranyl nitrilotriacetate, a stabilized salt of uranium, is genotoxic in nontransformed human colon cells and in the human colon adenoma cell line LT97.
Author:	Knobel, Yuonne\|Glei, Michael\|Weise, Anja\|Osswald, Kerstin\|Schaferhenrich, Anja\|Richter, Konrad Klaus\|Claussen, Uwe\|Pool-Zobel, Beatrice Louise
PMID:	16840563

469.
Journal:	J Pathol. 2006 Oct;210(2):147-54.
Title:	Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author:	Ogino, S\|Kawasaki, T\|Kirkner, G J\|Ogawa, A\|Dorfman, I\|Loda, M\|Fuchs, C S
PMID:	16850502

470.
Journal:	Histopathology. 2006 Aug;49(2):121-31.
Title:	Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer.
Author:	Jass, J R\|Baker, K\|Zlobec, I\|Higuchi, T\|Barker, M\|Buchanan, D\|Young, J
PMID:	16879389

471.
Journal:	Am J Clin Oncol. 2006 Aug;29(4):364-70.
Title:	Do MSI-L sporadic colorectal tumors develop through "mild mutator pathway"?
Author:	Oliart, Soledad\|Martinez-Santos, Cristina\|Moreno-Azcoita, Mariano\|Cerquella, Carlos\|Nejda, Nargisse\|Daimiel, Lydia\|Iglesias, Daniel\|Fernandez-Peralta, Antonia M\|Gonzalez-Aguilera, Juan J
PMID:	16891863

472.
Journal:	J Surg Oncol. 2006 Sep 1;94(3):234-41.
Title:	Distinctive clinicopathological features of Ki-ras mutated colorectal cancers.
Author:	Lin, Jen-Kou\|Chang, Shih-Ching\|Wang, Huann-Sheng\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Chen, Wei-Chone\|Lin, Tzu-Chen\|Li, Anna Fen-Yau
PMID:	16900509

473.
Journal:	J Pathol. 2006 Nov;210(3):344-50.
Title:	Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas.
Author:	Judson, H\|Stewart, A\|Leslie, A\|Pratt, N R\|Baty, D U\|Steele, R J C\|Carey, F A
PMID:	16902913

474.
Journal:	Alcohol. 2006 Apr;38(3):147-54.
Title:	Alcohol and the risk of colon and rectal cancer with mutations in the K-ras gene.
Author:	Bongaerts, Brenda W C\|de Goeij, Anton F P M\|van den Brandt, Piet A\|Weijenberg, Matty P
PMID:	16905440

475.
Journal:	J Exp Clin Cancer Res. 2006 Jun;25(2):235-42.
Title:	Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers.
Author:	Noda, H\|Kato, Y\|Yoshikawa, H\|Arai, M\|Togashi, K\|Nagai, H\|Konishi, F\|Miki, Y
PMID:	16918136

476.
Journal:	J Exp Clin Cancer Res. 2006 Jun;25(2):259-67.
Title:	K-ras 4A and 4B are co-expressed widely in human tissues, and their ratio is altered in sporadic colorectal cancer.
Author:	Plowman, S J\|Berry, R L\|Bader, S A\|Luo, F\|Arends, M J\|Harrison, D J\|Hooper, M L\|Patek, C E
PMID:	16918139

477.
Journal:	Diagn Mol Pathol. 2006 Sep;15(3):162-8.
Title:	Adequacy of colonoscopic biopsy specimens for molecular analysis: a comparative study with colectomy tissue.
Author:	Zauber, Neil P\|Sabbath-Solitare, Marlene\|Marotta, Stephen\|Perera, Lilani P\|Bishop, David T
PMID:	16932072

478.
Journal:	Cancer Biol Ther. 2006 Aug;5(8):928-32. Epub 2006 Aug 1.
Title:	Recurrent KRAS codon 146 mutations in human colorectal cancer.
Author:	Edkins, Sarah\|O'Meara, Sarah\|Parker, Adrian\|Stevens, Claire\|Reis, Marcelo\|Jones, Sian\|Greenman, Chris\|Davies, Helen\|Dalgliesh, Gillian\|Forbes, Simon\|Hunter, Chris\|Smith, Raffaella\|Stephens, Philip\|Goldstraw, Peter\|Nicholson, Andrew\|Chan, Tsun Leung\|Velcul
PMID:	16969076

479.
Journal:	Br J Cancer. 2006 Oct 23;95(8):1101-7.
Title:	Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.
Author:	Miranda, E\|Destro, A\|Malesci, A\|Balladore, E\|Bianchi, P\|Baryshnikova, E\|Franchi, G\|Morenghi, E\|Laghi, L\|Gennari, L\|Roncalli, M
PMID:	16969349

480.
Journal:	Cell Oncol. 2006;28(4):161-6.
Title:	KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression.
Author:	Calistri, Daniele\|Rengucci, Claudia\|Seymour, Ian\|Leonardi, Elena\|Truini, Mauro\|Malacarne, Davide\|Castagnola, Patrizio\|Giaretti, Walter
PMID:	16988471

481.
Journal:	Gastroenterology. 2006 Oct;131(4):1096-109. Epub 2006 Aug 16.
Title:	APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
Author:	Janssen, Klaus-Peter\|Alberici, Paola\|Fsihi, Hafida\|Gaspar, Claudia\|Breukel, Cor\|Franken, Patrick\|Rosty, Christophe\|Abal, Miguel\|El Marjou, Fatima\|Smits, Ron\|Louvard, Daniel\|Fodde, Riccardo\|Robine, Sylvie
PMID:	17030180

482.
Journal:	J Mol Diagn. 2006 Nov;8(5):582-8.
Title:	CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17065427

483.
Journal:	Clin Chem. 2006 Dec;52(12):2299-302.
Title:	Improved marker combination for detection of de novo genetic variation and aberrant DNA in colorectal neoplasia.
Author:	Kann, Lisa\|Han, James\|Ahlquist, David\|Levin, Theodore\|Rex, Douglas\|Whitney, Duncan\|Markowitz, Sanford\|Shuber, Anthony
PMID:	17082247

484.
Journal:	Oncol Rep. 2006 Dec;16(6):1245-52.
Title:	Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene.
Author:	Wang, Jaw-Yuan\|Wang, Yung-Hsin\|Jao, Shu-Wen\|Lu, Chien-Yu\|Kuo, Chao-Hung\|Hu, Huang-Ming\|Hsieh, Jan-Sing\|Chong, Inn-Wen\|Cheng, Tian-Lu\|Lin, Shiu-Ru
PMID:	17089045

485.
Journal:	Cancer Biother Radiopharm. 2006 Oct;21(5):488-505.
Title:	Colon cancer and gene alterations: their immunological implications and suggestions for prognostic indices and improvements in biotherapy.
Author:	Contasta, Ida\|Pellegrini, Patrizia\|Berghella, Anna Maria\|Del Beato, Tiziana\|Adorno, Domenico
PMID:	17105421

486.
Journal:	Am J Surg Pathol. 2006 Dec;30(12):1491-501.
Title:	Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points.
Author:	O'Brien, Michael J\|Yang, Shi\|Mack, Charline\|Xu, Huihong\|Huang, Christopher S\|Mulcahy, Elizabeth\|Amorosino, Mark\|Farraye, Francis A
PMID:	17122504

487.
Journal:	Cell Oncol. 2006;28(5-6):247-57.
Title:	Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Author:	Derks, Sarah\|Postma, Cindy\|Moerkerk, Peter T M\|van den Bosch, Sandra M\|Carvalho, Beatriz\|Hermsen, Mario A J A\|Giaretti, Walter\|Herman, James G\|Weijenberg, Matty P\|de Bruine, Adriaan P\|Meijer, Gerrit A\|van Engeland, Manon
PMID:	17167178

488.
Journal:	Int J Biol Markers. 2006 Oct-Dec;21(4):223-8.
Title:	Prognostic value of circulating KRAS2 gene mutations in colorectal cancer with distant metastases.
Author:	Trevisiol, C\|Di Fabio, F\|Nascimbeni, R\|Peloso, L\|Salbe, C\|Ferruzzi, E\|Salerni, B\|Gion, M
PMID:	17177160

489.
Journal:	Crit Rev Oncog. 2006 Dec;12(3-4):273-87.
Title:	Colorectal cancer: a multipathway disease.
Author:	Jass, Jeremy R
PMID:	17425506

490.
Journal:	Verh Dtsch Ges Pathol. 2006;90:18-24.
Title:	Types of colorectal adenoma.
Author:	Lugli, A\|Jass, J R
PMID:	17867575

491.
Journal:	Med Secoli. 2006;18(3):843-64.
Title:	[The Aragonese mummies of the Basilica of Saint Domenico Maggiore in Naples].
Author:	Fornaciari, Gino
PMID:	18175625

492.
Journal:	Oncogene. 2007 Jan 4;26(1):158-63. Epub 2006 Sep 4.
Title:	KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.
Author:	Oliveira, C\|Velho, S\|Moutinho, C\|Ferreira, A\|Preto, A\|Domingo, E\|Capelinha, A F\|Duval, A\|Hamelin, R\|Machado, J C\|Schwartz, S Jr\|Carneiro, F\|Seruca, R
PMID:	16953233

493.
Journal:	Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title:	Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Yamaji, Taiki\|Loda, Massimo\|Fuchs, Charles S
PMID:	17086168

494.
Journal:	Oncogene. 2007 May 10;26(21):3051-9. Epub 2006 Nov 20.
Title:	Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.
Author:	Keller, J W\|Haigis, K M\|Franklin, J L\|Whitehead, R H\|Jacks, T\|Coffey, R J
PMID:	17130841

495.
Journal:	J Cell Physiol. 2007 Mar;210(3):740-9.
Title:	Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium.
Author:	Keller, Jeffrey W\|Franklin, Jeffrey L\|Graves-Deal, Ramona\|Friedman, David B\|Whitwell, Corbin W\|Coffey, Robert J
PMID:	17133351

496.
Journal:	Virchows Arch. 2007 Feb;450(2):151-9.
Title:	Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations.
Author:	Schmitz, K J\|Wohlschlaeger, J\|Alakus, H\|Bohr, J\|Stauder, M A\|Worm, K\|Winde, G\|Schmid, K W\|Baba, H A
PMID:	17149612

497.
Journal:	Biochem Biophys Res Commun. 2007 Jan 19;352(3):728-32. Epub 2006 Nov 27.
Title:	Characterization of a novel oncogenic K-ras mutation in colon cancer.
Author:	Akagi, Kiwamu\|Uchibori, Ryosuke\|Yamaguchi, Kensei\|Kurosawa, Keiko\|Tanaka, Yoichiro\|Kozu, Tomoko
PMID:	17150185

498.
Journal:	Int J Biochem Cell Biol. 2007;39(4):672-7. Epub 2006 Nov 3.
Title:	Colorectal cancer: potential therapeutic benefits of Vitamin D.
Author:	Jimenez-Lara, Ana M
PMID:	17157547

499.
Journal:	Toxicol Sci. 2007 Apr;96(2):279-84.
Title:	Comet fluorescence in situ hybridization analysis for oxidative stress-induced DNA damage in colon cancer relevant genes.
Author:	Glei, Michael\|Schaeferhenrich, Anja\|Claussen, Uwe\|Kuechler, Alma\|Liehr, Thomas\|Weise, Anja\|Marian, Brigitte\|Sendt, Wolfgang\|Pool-Zobel, Beatrice L
PMID:	17192441

500.
Journal:	Am J Pathol. 2007 Jan;170(1):377-87.
Title:	Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human.
Author:	Alberici, Paola\|de Pater, Emma\|Cardoso, Joana\|Bevelander, Mieke\|Molenaar, Lia\|Jonkers, Jos\|Fodde, Riccardo
PMID:	17200209

501.
Journal:	Oncol Rep. 2007 Feb;17(2):399-407.
Title:	Expression analysis of pancreatic cancer cell lines reveals association of enhanced gene transcription and genomic amplifications at the 8q22.1 and 8q24.22 loci.
Author:	Domagk, Dirk\|Schaefer, Karl-Ludwig\|Eisenacher, Martin\|Braun, Yvonne\|Wai, Daniel H\|Schleicher, Christina\|Diallo-Danebrock, Raihanatou\|Bojar, Hans\|Roeder, Gernot\|Gabbert, Helmut E\|Domschke, Wolfram\|Poremba, Christopher
PMID:	17203180

502.
Journal:	Histopathology. 2007 Jan;50(1):113-30.
Title:	Classification of colorectal cancer based on correlation of clinical, morphological and molecular features.
Author:	Jass, J R
PMID:	17204026

503.
Journal:	Mol Cancer Ther. 2007 Jan;6(1):269-76.
Title:	Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.
Author:	Sarthy, Aparna V\|Morgan-Lappe, Susan E\|Zakula, Dorothy\|Vernetti, Lawrence\|Schurdak, Mark\|Packer, Jeremy C L\|Anderson, Mark G\|Shirasawa, Senji\|Sasazuki, Takehiko\|Fesik, Stephen W
PMID:	17237286

504.
Journal:	Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title:	Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17239930

505.
Journal:	Transl Res. 2007 Feb;149(2):96-102.
Title:	Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC).
Author:	Chien, Chih-Cheng\|Chen, Shu-Hung\|Liu, Chen-Chiung\|Lee, Chia-Long\|Yang, Ruey-Neng\|Yang, Shung-Haur\|Huang, Chi-Jung
PMID:	17240321

506.
Journal:	Gastroenterology. 2007 Feb;132(2):527-30. Epub 2006 Nov 29.
Title:	Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
Author:	Will, Olivia\|Carvajal-Carmona, Luis G\|Gorman, Patricia\|Howarth, Kimberley M\|Jones, Angela M\|Polanco-Echeverry, Guadalupe M\|Chinaleong, Jo-Anne\|Gunther, Thomas\|Silver, Andrew\|Clark, Susan K\|Tomlinson, Ian
PMID:	17258725

507.
Journal:	Oncogene. 2007 Jun 28;26(30):4435-41. Epub 2007 Jan 29.
Title:	Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.
Author:	Kohonen-Corish, M R J\|Sigglekow, N D\|Susanto, J\|Chapuis, P H\|Bokey, E L\|Dent, O F\|Chan, C\|Lin, B P C\|Seng, T J\|Laird, P W\|Young, J\|Leggett, B A\|Jass, J R\|Sutherland, R L
PMID:	17260021

508.
Journal:	Gut. 2007 Jul;56(7):926-33. Epub 2007 Jan 31.
Title:	Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study.
Author:	Gylling, A\|Abdel-Rahman, W M\|Juhola, M\|Nuorva, K\|Hautala, E\|Jarvinen, H J\|Mecklin, J-P\|Aarnio, M\|Peltomaki, P
PMID:	17267619

509.
Journal:	Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title:	TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17270239

510.
Journal:	Int J Cancer. 2007 May 15;120(10):2226-32.
Title:	Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival.
Author:	Curtin, Karen\|Ulrich, Cornelia M\|Samowitz, Wade S\|Bigler, Jeannette\|Caan, Bette\|Potter, John D\|Slattery, Martha L
PMID:	17290389

511.
Journal:	Mol Cancer Res. 2007 Feb;5(2):165-70. Epub 2007 Feb 9.
Title:	APC mutations and other genetic and epigenetic changes in colon cancer.
Author:	Samowitz, Wade S\|Slattery, Martha L\|Sweeney, Carol\|Herrick, Jennifer\|Wolff, Roger K\|Albertsen, Hans
PMID:	17293392

512.
Journal:	Mol Cancer Res. 2007 Feb;5(2):195-201.
Title:	Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.
Author:	Hollestelle, Antoinette\|Elstrodt, Fons\|Nagel, Jord H A\|Kallemeijn, Wouter W\|Schutte, Mieke
PMID:	17314276

513.
Journal:	Cell Signal. 2007 Jul;19(7):1465-72. Epub 2007 Jan 24.
Title:	BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK.
Author:	Beck, Stayce E\|Jung, Barbara H\|Del Rosario, Eunice\|Gomez, Jessica\|Carethers, John M
PMID:	17317101

514.
Journal:	Clin Chem. 2007 Apr;53(4):787-90. Epub 2007 Feb 22.
Title:	Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras mutations in stool DNA: high prevalence in a large sample of older adults.
Author:	Haug, Ulrike\|Hillebrand, Timo\|Bendzko, Peter\|Low, Michael\|Rothenbacher, Dietrich\|Stegmaier, Christa\|Brenner, Hermann
PMID:	17317884

515.
Journal:	Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title:	Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	17339237

516.
Journal:	Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title:	Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17350669

517.
Journal:	Int J Cancer. 2007 Jun 15;120(12):2734-8.
Title:	Chromosomal 20q gain in the DNA diploid component of aneuploid colorectal carcinomas.
Author:	De Angelis, Paula M\|Stokke, Trond\|Beigi, Marzieh\|Flatberg, Goril\|Enger, Marianne\|Haug, Kristiane\|Aass, Hans Christian D\|Schjolberg, Aasa\|Andresen, Per Arne\|Ariansen, Sarah\|Bo, Anne Signe\|Mjaland, Odd\|Clausen, Ole Petter
PMID:	17354231

518.
Journal:	Oncol Rep. 2007 May;17(5):1095-9.
Title:	Loss of Smad4 expression predicts liver metastasis in human colorectal cancer.
Author:	Losi, Lorena\|Bouzourene, Hanifa\|Benhattar, Jean
PMID:	17390050

519.
Journal:	Int J Biol Markers. 2007 Jan-Mar;22(1):12-8.
Title:	Highly conserved sequence of exon 15 BRAF gene and KRAS codon 12 mutation among Greek patients with colorectal cancer.
Author:	Symvoulakis, E K\|Zaravinos, A\|Panutsopulos, D\|Zoras, O\|Papalambros, E\|Sigala, F\|Spandidos, D A
PMID:	17393356

520.
Journal:	J Gastrointestin Liver Dis. 2007 Mar;16(1):11-7.
Title:	Clinical significance of p53, K-ras and DCC gene alterations in the stage I-II colorectal cancers.
Author:	Akkiprik, Mustafa\|Ataizi-Celikel, Cigdem\|Dusunceli, Fikret\|Sonmez, Ozgur\|Gulluoglu, Bahadir M\|Sav, Aydin\|Ozer, Ayse
PMID:	17410283

521.
Journal:	Cancer Res. 2007 Apr 15;67(8):3551-4.
Title:	Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans.
Author:	Rosenberg, Daniel W\|Yang, Shi\|Pleau, Devon C\|Greenspan, Emily J\|Stevens, Richard G\|Rajan, Thiruchandurai V\|Heinen, Christopher D\|Levine, Joel\|Zhou, Yijian\|O'Brien, Michael J
PMID:	17440063

522.
Journal:	Cancer J. 2007 Jan-Feb;13(1):49-55.
Title:	Targeting aberrant chromatin structure in colorectal carcinomas.
Author:	Konishi, Kazuo\|Issa, Jean-Pierre J
PMID:	17464246

523.
Journal:	World J Gastroenterol. 2007 Apr 14;13(14):2048-52.
Title:	Histopathological and genetic differences between polypoid and non-polypoid submucosal colorectal carcinoma.
Author:	Hirata, Ichiro\|Wang, Fang-Yu\|Murano, Mitsuyuki\|Inoue, Takuya\|Toshina, Ken\|Nishikawa, Takashi\|Maemura, Kentaro
PMID:	17465446

524.
Journal:	BMC Cancer. 2007 May 2;7:72.
Title:	18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Ohnishi, Mutsuko\|Fuchs, Charles S
PMID:	17474983

525.
Journal:	J Pathol. 2007 Aug;212(4):378-85.
Title:	Molecular classification and genetic pathways in hyperplastic polyposis syndrome.
Author:	Carvajal-Carmona, L G\|Howarth, K M\|Lockett, M\|Polanco-Echeverry, G M\|Volikos, E\|Gorman, M\|Barclay, E\|Martin, L\|Jones, A M\|Saunders, B\|Guenther, T\|Donaldson, A\|Paterson, J\|Frayling, I\|Novelli, M R\|Phillips, R\|Thomas, H J W\|Silver, A\|Atkin, W\|Tomlinson, I P
PMID:	17503413

526.
Journal:	J Pathol. 2007 Jul;212(3):260-8.
Title:	Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer.
Author:	Zlobec, I\|Lugli, A\|Baker, K\|Roth, S\|Minoo, P\|Hayashi, S\|Terracciano, L\|Jass, J R
PMID:	17516584

527.
Journal:	Diagn Mol Pathol. 2007 Jun;16(2):91-5.
Title:	Limitations in molecular detection of lymph node micrometastasis from colorectal cancer.
Author:	Klebig, Felix\|Fischer, Carsten\|Petri, Susan\|Gerull, Helwe\|Wagener, Christoph\|Tschentscher, Peter
PMID:	17525678

528.
Journal:	Int J Cancer. 2007 Oct 15;121(8):1717-23.
Title:	Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer.
Author:	Rohde, Franziska\|Rimkus, Caroline\|Friederichs, Jan\|Rosenberg, Robert\|Marthen, Carmen\|Doll, Dietrich\|Holzmann, Bernhard\|Siewert, Jorg-Rudiger\|Janssen, Klaus-Peter
PMID:	17565744

529.
Journal:	J Mol Diagn. 2007 Jul;9(3):305-14.
Title:	Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Kraft, Peter\|Loda, Massimo\|Fuchs, Charles S
PMID:	17591929

530.
Journal:	Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title:	MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author:	Ogino, Shuji\|Hazra, Aditi\|Tranah, Gregory J\|Kirkner, Gregory J\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Hunter, David J\|Fuchs, Charles S
PMID:	17621591

531.
Journal:	Eur J Gastroenterol Hepatol. 2007 Aug;19(8):725-7.
Title:	Stool DNA analysis detects premorphological colorectal neoplasia: a case report.
Author:	Ogreid, Dagfinn\|Hamre, Erik
PMID:	17625445

532.
Journal:	Pathol Res Pract. 2007;203(7):489-97. Epub 2007 Jul 12.
Title:	K-ras mutation detection in colorectal cancer using the Pyrosequencing technique.
Author:	Poehlmann, Angela\|Kuester, Doerthe\|Meyer, Frank\|Lippert, Hans\|Roessner, Albert\|Schneider-Stock, Regine
PMID:	17629419

533.
Journal:	Cancer Causes Control. 2007 Oct;18(8):865-79. Epub 2007 Jul 18.
Title:	Dietary fat and risk of colon and rectal cancer with aberrant MLH1 expression, APC or KRAS genes.
Author:	Weijenberg, Matty P\|Luchtenborg, Margreet\|de Goeij, Anton F P M\|Brink, Mirian\|van Muijen, Goos N P\|de Bruine, Adriaan P\|Goldbohm, R Alexandra\|van den Brandt, Piet A
PMID:	17636402

534.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jul;27(7):1018-21.
Title:	[Value of fecal and blood adenomatous polyposis coli gene and K-ras gene mutation detection in colorectal neoplasm screening].
Author:	Zhan, Jun\|Li, Xin\|Yu, Zhong\|Yuan, Yu-hong\|Hou, Jing
PMID:	17666342

535.
Journal:	Carcinogenesis. 2007 Sep;28(9):1851-8. Epub 2007 Aug 11.
Title:	Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns.
Author:	Lea, I A\|Jackson, M A\|Li, X\|Bailey, S\|Peddada, S D\|Dunnick, J K
PMID:	17693665

536.
Journal:	J Int Med Res. 2007 Jul-Aug;35(4):450-7.
Title:	No duplicate KRAS mutation is identified on the same allele in gastric or colorectal cancer cells with multiple KRAS mutations.
Author:	Kimura, K\|Nagasaka, T\|Hoshizima, N\|Sasamoto, H\|Notohara, K\|Takeda, M\|Kominami, K\|Iishii, T\|Tanaka, N\|Matsubara, N
PMID:	17697521

537.
Journal:	Hum Pathol. 2007 Nov;38(11):1696-702.
Title:	High-degree tumor budding and podia-formation in sporadic colorectal carcinomas with K-ras gene mutations.
Author:	Prall, Friedrich\|Ostwald, Christiane
PMID:	17707462

538.
Journal:	Neoplasia. 2007 Jul;9(7):536-45.
Title:	Acquisition of anoikis resistance promotes the emergence of oncogenic K-ras mutations in colorectal cancer cells and stimulates their tumorigenicity in vivo.
Author:	Derouet, Mathieu\|Wu, Xue\|May, Linda\|Hoon Yoo, Byong\|Sasazuki, Takehiko\|Shirasawa, Senji\|Rak, Janusz\|Rosen, Kirill V
PMID:	17710156

539.
Journal:	Lab Chip. 2007 Sep;7(9):1162-70.
Title:	DNA mutation detection with chip-based temperature gradient capillary electrophoresis using a slantwise radiative heating system.
Author:	Zhang, Hui-Dan\|Zhou, Jing\|Xu, Zhang-Run\|Song, Jin\|Dai, Jing\|Fang, Jin\|Fang, Zhao-Lun
PMID:	17713615

540.
Journal:	Eur J Gastroenterol Hepatol. 2007 Oct;19(10):883-9.
Title:	P21WAF1/CIP1 expression in colorectal carcinomas is related to Kras mutations and prognosis.
Author:	Mitomi, Hiroyuki\|Ohkura, Yasuo\|Fukui, Naoshi\|Kanazawa, Hideki\|Kishimoto, Ichiro\|Nakamura, Takatoshi\|Yokoyama, Kaoru\|Sada, Miwa\|Kobayashi, Kiyonori\|Tanabe, Satoshi\|Saigenji, Katsunori
PMID:	17873613

541.
Journal:	Clin Cancer Res. 2007 Oct 1;13(19):5729-35.
Title:	Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.
Author:	Sanchez-de-Abajo, Ana\|de la Hoya, Miguel\|van Puijenbroek, Marjo\|Tosar, Alicia\|Lopez-Asenjo, J A\|Diaz-Rubio, Eduardo\|Morreau, Hans\|Caldes, Trinidad
PMID:	17908962

542.
Journal:	Oncol Rep. 2007 Nov;18(5):1093-7.
Title:	Involvement of the serrated neoplasia pathway in inflammatory bowel disease-related colorectal oncogenesis.
Author:	Bossard, Celine\|Denis, Marc G\|Bezieau, Stephane\|Bach-Ngohou, Kalyane\|Bourreille, Arnaud\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	17914558

543.
Journal:	J Hum Genet. 2007;52(12):978-84.
Title:	Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line.
Author:	Fujimoto, Takahiro\|Koyanagi, Midori\|Baba, Iwai\|Nakabayashi, Kazuhiko\|Kato, Norihiro\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	17934691

544.
Journal:	Gastroenterol Clin North Am. 2007 Dec;36(4):947-68, viii.
Title:	Hyperplastic and serrated polyps of the colorectum.
Author:	O'Brien, Michael J
PMID:	17996799

545.
Journal:	Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18654-9. Epub 2007 Nov 14.
Title:	Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.
Author:	Shen, Lanlan\|Toyota, Minoru\|Kondo, Yutaka\|Lin, E\|Zhang, Li\|Guo, Yi\|Hernandez, Natalie Supunpong\|Chen, Xinli\|Ahmed, Saira\|Konishi, Kazuo\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	18003927

546.
Journal:	Cancer Res. 2007 Nov 15;67(22):10766-73.
Title:	Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer.
Author:	Santiago, Cariluz\|Pagan, Beatriz\|Isidro, Angel A\|Appleyard, Caroline B
PMID:	18006820

547.
Journal:	Gastroenterol Hepatol. 2007 Dec;30(10):592-6.
Title:	[Genetic profile and molecular bases of pancreatic carcinogenesis].
Author:	Sanchez-Fayos Calabuig, Paloma\|Martin Relloso, Maria Jesus\|Porres Cubero, Juan Carlos
PMID:	18028855

548.
Journal:	Cancer Res. 2007 Dec 15;67(24):11594-600.
Title:	Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.
Author:	Uronis, Joshua M\|Herfarth, Hans H\|Rubinas, Tara C\|Bissahoyo, Anika C\|Hanlon, Kathleen\|Threadgill, David W
PMID:	18089788

549.
Journal:	Hepatogastroenterology. 2007 Dec;54(80):2259-65.
Title:	The differentially mutational spectra of the APC, K-ras, and p53 genes in sporadic colorectal cancers from Taiwanese patients.
Author:	Wang, Jaw-Yuan\|Hsieh, Jan-Sing\|Lu, Chien-Yu\|Yu, Fang-Jung\|Wu, Jeng-Yih\|Chen, Fang-Ming\|Huang, Che-Jen\|Lin, Shiu-Ru
PMID:	18265644

550.
Journal:	Int J Colorectal Dis. 2008 Jan;23(1):7-13. Epub 2007 Oct 9.
Title:	Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer.
Author:	Yoshida, Shiei\|Ikehara, Nobunao\|Aoyama, Nobuo\|Shirasaka, Daisuke\|Sakashita, Masanori\|Semba, Shuho\|Hasuo, Tadateru\|Miki, Ikuya\|Morita, Yoshinori\|Tamura, Takao\|Azuma, Takeshi\|Yokozaki, Hiroshi\|Kasuga, Masato
PMID:	17924122

551.
Journal:	Hum Mutat. 2008 Feb;29(2):284-8.
Title:	PIK3CA cancer mutations display gender and tissue specificity patterns.
Author:	Benvenuti, Silvia\|Frattini, Milo\|Arena, Sabrina\|Zanon, Carlo\|Cappelletti, Vera\|Coradini, Danila\|Daidone, Maria Grazia\|Pilotti, Silvana\|Pierotti, Marco A\|Bardelli, Alberto
PMID:	18022911

552.
Journal:	Gastroenterology. 2008 Jan;134(1):120-30. Epub 2007 Oct 17.
Title:	Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis.
Author:	Nandan, Mandayam O\|McConnell, Beth B\|Ghaleb, Amr M\|Bialkowska, Agnieszka B\|Sheng, Hongmiao\|Shao, Jinyi\|Babbin, Brian A\|Robine, Sylvie\|Yang, Vincent W
PMID:	18054006

553.
Journal:	Genes Chromosomes Cancer. 2008 Mar;47(3):253-9.
Title:	SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients.
Author:	Swanson, Kenneth D\|Winter, Jordan M\|Reis, Marcelo\|Bentires-Alj, Mohamed\|Greulich, Heidi\|Grewal, Rupinder\|Hruban, Ralph H\|Yeo, Charles J\|Yassin, Yosuf\|Iartchouk, Oleg\|Montgomery, Kate\|Whitman, Susan P\|Caligiuri, Michael A\|Loh, Mignon L\|Gilliland, D Gary\|Lo
PMID:	18064648

554.
Journal:	Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title:	WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Liu, Zhiqian\|Yamamoto, Hiroyuki\|Loda, Massimo\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18084250

555.
Journal:	Int J Oncol. 2008 Jan;32(1):153-9.
Title:	Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rgammanull (NOG) mice.
Author:	Hamada, Kenji\|Monnai, Makoto\|Kawai, Kenji\|Nishime, Chiyoko\|Kito, Chika\|Miyazaki, Noriyuki\|Ohnishi, Yasuyuki\|Nakamura, Masato\|Suemizu, Hiroshi
PMID:	18097554

556.
Journal:	Int J Cancer. 2008 Apr 15;122(8):1745-56.
Title:	Fra-1 regulates vimentin during Ha-RAS-induced epithelial mesenchymal transition in human colon carcinoma cells.
Author:	Andreolas, Chrysovalantis\|Kalogeropoulou, Margarita\|Voulgari, Angeliki\|Pintzas, Alexander
PMID:	18098284

557.
Journal:	J Pathol. 2008 Feb;214(3):320-7.
Title:	BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
Author:	Preto, A\|Figueiredo, J\|Velho, S\|Ribeiro, A S\|Soares, P\|Oliveira, C\|Seruca, R
PMID:	18098337

558.
Journal:	Clin Cancer Res. 2008 Jan 1;14(1):139-42.
Title:	Identification of patients with (atypical) MUTYH-associated polyposis by KRAS2 c.34G > T prescreening followed by MUTYH hotspot analysis in formalin-fixed paraffin-embedded tissue.
Author:	van Puijenbroek, Marjo\|Nielsen, Maartje\|Tops, Carli M J\|Halfwerk, Hans\|Vasen, Hans F A\|Weiss, Marjan M\|van Wezel, Tom\|Hes, Frederik J\|Morreau, Hans
PMID:	18172263

559.
Journal:	Mol Carcinog. 2008 Jul;47(7):538-53.
Title:	Activated K-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis.
Author:	Roy, Upal K Basu\|Rial, Nathaniel S\|Kachel, Karen L\|Gerner, Eugene W
PMID:	18176934

560.
Journal:	Hum Mutat. 2008 Mar;29(3):441-50.
Title:	Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD).
Author:	Bentivegna, Steven\|Zheng, Jianbiao\|Namsaraev, Eugeni\|Carlton, Victoria E H\|Pavlicek, Adam\|Moorhead, Martin\|Siddiqui, Farooq\|Wang, Zhiyong\|Lee, Liana\|Ireland, James S\|Suyenaga, Kent\|Willis, Thomas D\|Faham, Malek\|Seymour, Albert B
PMID:	18186519

561.
Journal:	Carcinogenesis. 2008 Mar;29(3):647-55.
Title:	Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells.
Author:	Seiden-Long, Isolde\|Navab, Roya\|Shih, Warren\|Li, Ming\|Chow, Jane\|Zhu, Chang Qi\|Radulovich, Nikolina\|Saucier, Caroline\|Tsao, Ming-Sound
PMID:	18192688

562.
Journal:	Pathol Int. 2008 Feb;58(2):104-13.
Title:	Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.
Author:	Lee, Sun\|Cho, Nam-Yun\|Choi, Minhee\|Yoo, Eun J\|Kim, Jung-Ho\|Kang, Gyeong H
PMID:	18199160

563.
Journal:	J Clin Oncol. 2008 Jan 20;26(3):374-9.
Title:	KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.
Author:	Lievre, Astrid\|Bachet, Jean-Baptiste\|Boige, Valerie\|Cayre, Anne\|Le Corre, Delphine\|Buc, Emmanuel\|Ychou, Marc\|Bouche, Olivier\|Landi, Bruno\|Louvet, Christophe\|Andre, Thierry\|Bibeau, Frederic\|Diebold, Marie-Daniele\|Rougier, Philippe\|Ducreux, Michel\|Tomasic,
PMID:	18202412

564.
Journal:	Crit Rev Oncol Hematol. 2008 Apr;66(1):21-30.
Title:	Potential predictive markers of response to EGFR-targeted therapies in colorectal cancer.
Author:	Spano, Jean Philippe\|Milano, Gerard\|Vignot, Stephane\|Khayat, David
PMID:	18206383

565.
Journal:	Pathologe. 2008 Feb;29(1):93-6.
Title:	[Molecular pathology analysis of the KRAS mutation status in patients with metastasized colorectal carcinoma: an initial approach using predictive pathology].
Author:	Tannapfel, A
PMID:	18210112

566.
Journal:	Cell Oncol. 2008;30(1):1-11.
Title:	Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases.
Author:	Veenendaal, Liesbeth M\|Kranenburg, Onno\|Smakman, Niels\|Klomp, Annemarie\|Borel Rinkes, Inne H M\|van Diest, Paul J
PMID:	18219106

567.
Journal:	Int J Cancer. 2008 May 15;122(10):2255-9.
Title:	Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.
Author:	Barault, Ludovic\|Veyrie, Nicolas\|Jooste, Valerie\|Lecorre, Delphine\|Chapusot, Caroline\|Ferraz, Jean-Marc\|Lievre, Astrid\|Cortet, Marion\|Bouvier, Anne-Marie\|Rat, Patrick\|Roignot, Patrick\|Faivre, Jean\|Laurent-Puig, Pierre\|Piard, Francoise
PMID:	18224685

568.
Journal:	Bull Cancer. 2008 Jan;95(1):133-40.
Title:	[Predictive factors of response to anti-EGFR treatments in colorectal cancer].
Author:	Lievre, Astrid\|Laurent-Puig, Pierre
PMID:	18230579

569.
Journal:	Int J Cancer. 2008 Jun 1;122(11):2429-36.
Title:	Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.
Author:	Nagasaka, Takeshi\|Goel, Ajay\|Notohara, Kenji\|Takahata, Takaomi\|Sasamoto, Hiromi\|Uchida, Takuyuki\|Nishida, Naoshi\|Tanaka, Noriaki\|Boland, Clement Richard\|Matsubara, Nagahide
PMID:	18240147

570.
Journal:	Cancer Gene Ther. 2008 May;15(5):284-92.
Title:	Transient infection of freshly isolated human colorectal tumor cells by reovirus T3D intermediate subviral particles.
Author:	van Houdt, W J\|Smakman, N\|van den Wollenberg, D J M\|Emmink, B L\|Veenendaal, L M\|van Diest, P J\|Hoeben, R C\|Borel Rinkes, I H M\|Kranenburg, O
PMID:	18259212

571.
Journal:	Int J Cancer. 2008 Jun 1;122(11):2462-70.
Title:	Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon.
Author:	Calcagno, Shelly R\|Li, Shuhua\|Colon, Migdalisel\|Kreinest, Pamela A\|Thompson, E Aubrey\|Fields, Alan P\|Murray, Nicole R
PMID:	18271008

572.
Journal:	Mutat Res. 2008 Mar 29;652(1):54-64.
Title:	Cigarette smoking and KRAS oncogene mutations in sporadic colorectal cancer: results from the Netherlands Cohort Study.
Author:	Weijenberg, M P\|Aardening, P W M\|de Kok, T M\|de Goeij, A F P M\|van den Brandt, P A
PMID:	18296105

573.
Journal:	Am J Surg Pathol. 2008 Mar;32(3):407-12.
Title:	Serrated polyps with "intermediate features" of sessile serrated polyp and microvesicular hyperplastic polyp: a practical approach to the classification of nondysplastic serrated polyps.
Author:	Chung, Sun M\|Chen, Yao-Tseng\|Panczykowski, Andrea\|Schamberg, Neal\|Klimstra, David S\|Yantiss, Rhonda K
PMID:	18300810

574.
Journal:	J Clin Oncol. 2008 Apr 1;26(10):1626-34.
Title:	Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.
Author:	Amado, Rafael G\|Wolf, Michael\|Peeters, Marc\|Van Cutsem, Eric\|Siena, Salvatore\|Freeman, Daniel J\|Juan, Todd\|Sikorski, Robert\|Suggs, Sid\|Radinsky, Robert\|Patterson, Scott D\|Chang, David D
PMID:	18316791

575.
Journal:	Biochem Biophys Res Commun. 2008 May 23;370(1):189-94.
Title:	Anti-tumor activity of ESX1 on cancer cells harboring oncogenic K-ras mutation.
Author:	Nakajima, Junta\|Ishikawa, Susumu\|Hamada, Jun-Ichi\|Yanagihara, Masatomo\|Koike, Takao\|Hatakeyama, Masanori
PMID:	18361917

576.
Journal:	Nat Genet. 2008 May;40(5):600-8.
Title:	Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Author:	Haigis, Kevin M\|Kendall, Krystle R\|Wang, Yufang\|Cheung, Ann\|Haigis, Marcia C\|Glickman, Jonathan N\|Niwa-Kawakita, Michiko\|Sweet-Cordero, Alejandro\|Sebolt-Leopold, Judith\|Shannon, Kevin M\|Settleman, Jeffrey\|Giovannini, Marco\|Jacks, Tyler
PMID:	18372904

577.
Journal:	Pharmacogenomics. 2008 Apr;9(4):463-7.
Title:	DxS Ltd.
Author:	Cross, Joanne
PMID:	18384259

578.
Journal:	Turk J Gastroenterol. 2008 Mar;19(1):22-7.
Title:	Relationship between overexpression of ras p21 oncoprotein and K-ras codon 12 and 13 mutations in Turkish colorectal cancer patients.
Author:	Akkiprik, Mustafa\|Celikel, Cigdem Ataizi\|Dusunceli, Fikret\|Sonmez, Ozgur\|Gulluoglu, Bahadir M\|Sav, Aydin\|Ozer, Ayse
PMID:	18386236

579.
Journal:	Mol Diagn Ther. 2008;12(2):87-98.
Title:	The role of molecular markers in predicting response to therapy in patients with colorectal cancer.
Author:	Shankaran, Veena\|Wisinski, Kari B\|Mulcahy, Mary F\|Benson, Al B 3rd
PMID:	18422373

580.
Journal:	Chirurg. 2008 Jun;79(6):576-9.
Title:	[Molecular pathologic KRAS mutation analysis. A prerequisite of effective antibody treatment for metastasized colorectal cancer].
Author:	Dietel, M\|Tannapfel, A\|Baretton, G\|Kreipe, H\|Kloor, M\|Gabbert, H\|Kirchner, T
PMID:	18431556

581.
Journal:	Rozhl Chir. 2008 Jan;87(1):32-7.
Title:	[K-ras mutation as a prognostic factor in colorectal carcinoma].
Author:	Sacha, M\|Havlicek, K\|Sakra, L\|Rajman, M\|Beranek, M
PMID:	18432074

582.
Journal:	Gastroenterology. 2008 Jun;134(7):1950-60, 1960.e1.
Title:	Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer.
Author:	Nagasaka, Takeshi\|Koi, Minoru\|Kloor, Matthias\|Gebert, Johannes\|Vilkin, Alex\|Nishida, Naoshi\|Shin, Sung Kwan\|Sasamoto, Hiromi\|Tanaka, Noriaki\|Matsubara, Nagahide\|Boland, C Richard\|Goel, Ajay
PMID:	18435933

583.
Journal:	Mod Pathol. 2008 May;21 Suppl 2:S23-30.
Title:	Targeted therapy of cancer: new roles for pathologists in colorectal cancer.
Author:	Hamilton, Stanley R
PMID:	18437170

584.
Journal:	Clin Cancer Res. 2008 May 1;14(9):2560-9.
Title:	Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Author:	Suehiro, Yutaka\|Wong, Chi Wai\|Chirieac, Lucian R\|Kondo, Yutaka\|Shen, Lanlan\|Webb, C Renee\|Chan, Yee Wai\|Chan, Annie S Y\|Chan, Tsun Leung\|Wu, Tsung-Teh\|Rashid, Asif\|Hamanaka, Yuichiro\|Hinoda, Yuji\|Shannon, Rhonda L\|Wang, Xuemei\|Morris, Jeffrey\|Issa, Jean-P
PMID:	18451217

585.
Journal:	Eur J Cancer. 2008 Jun;44(9):1290-301.
Title:	Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.
Author:	Deng, Guoren\|Kakar, Sanjay\|Tanaka, Hirofumi\|Matsuzaki, Koji\|Miura, Soichiro\|Sleisenger, Marvin H\|Kim, Young S
PMID:	18486467

586.
Journal:	J Clin Oncol. 2008 May 20;26(15):2600; author reply 2601-2.
Title:	Should KRAS mutations be considered an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab?
Author:	Garassino, Marina Chiara\|Farina, Gabriella\|Rossi, Antonio\|Martelli, Olga\|Torri, Valter
PMID:	18487581

587.
Journal:	Neoplasia. 2008 Jun;10(6):534-41.
Title:	PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author:	Nosho, Katsuhiko\|Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Zepf, Dimity\|Yan, Liying\|Longtine, Janina A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18516290

588.
Journal:	Arch Pathol Lab Med. 2008 Jun;132(6):958-64.
Title:	Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability.
Author:	Kakar, Sanjay\|Deng, Guoren\|Sahai, Vaibhav\|Matsuzaki, Koji\|Tanaka, Hirofumi\|Miura, Soichuro\|Kim, Young S
PMID:	18517279

589.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title:	In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author:	Ikediobi, Ogechi N\|Reimers, Mark\|Durinck, Steffen\|Blower, Paul E\|Futreal, Andrew P\|Stratton, Michael R\|Weinstein, John N
PMID:	18524847

590.
Journal:	Curr Opin Oncol. 2008 Jul;20(4):454-8.
Title:	Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer?
Author:	Laurent-Puig, Pierre\|Taieb, Julien
PMID:	18525343

591.
Journal:	BMC Cancer. 2008 Jun 10;8:169.
Title:	A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment.
Author:	Goncalves, Anthony\|Esteyries, Severine\|Taylor-Smedra, Brynn\|Lagarde, Arnaud\|Ayadi, Mounay\|Monges, Genevieve\|Bertucci, Francois\|Esterni, Benjamin\|Delpero, Jean-Robert\|Turrini, Olivier\|Lelong, Bernard\|Viens, Patrice\|Borg, Jean-Paul\|Birnbaum, Daniel\|Olschwan
PMID:	18544172

592.
Journal:	Int J Cancer. 2008 Sep 1;123(5):1060-7.
Title:	p73 Isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis.
Author:	Diaz, Raquel\|Pena, Cristina\|Silva, Javier\|Lorenzo, Yolanda\|Garcia, Vanesa\|Garcia, Jose M\|Sanchez, Antonio\|Espinosa, Pablo\|Yuste, Rosario\|Bonilla, Felix\|Dominguez, Gemma
PMID:	18546269

593.
Journal:	Carcinogenesis. 2008 Jul;29(7):1351-9.
Title:	Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors.
Author:	Gylling, A H S\|Nieminen, T T\|Abdel-Rahman, W M\|Nuorva, K\|Juhola, M\|Joensuu, E I\|Jarvinen, H J\|Mecklin, J-P\|Aarnio, M\|Peltomaki, P T
PMID:	18550572

594.
Journal:	BMC Gastroenterol. 2008 Jun 13;8:24.
Title:	The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.
Author:	Patek, Charles E\|Arends, Mark J\|Rose, Lorraine\|Luo, Feijun\|Walker, Marion\|Devenney, Paul S\|Berry, Rachel L\|Lawrence, Nicola J\|Ridgway, Rachel A\|Sansom, Owen J\|Hooper, Martin L
PMID:	18554389

595.
Journal:	Biochem Pharmacol. 2008 Jul 15;76(2):198-207.
Title:	Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: the role of p53 and p21.
Author:	Escandell, Jose M\|Kaler, Pawan\|Recio, M Carmen\|Sasazuki, Takehiko\|Shirasawa, Senji\|Augenlicht, Leonard\|Rios, Jose-Luis\|Klampfer, Lidija
PMID:	18561895

596.
Journal:	World J Gastroenterol. 2008 Jun 14;14(22):3461-3.
Title:	Heterogeneity of colorectal adenomas, the serrated adenoma, and implications for screening and surveillance.
Author:	Freeman, Hugh-James
PMID:	18567071

597.
Journal:	Br J Cancer. 2008 Jul 8;99(1):83-9.
Title:	Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.
Author:	Cappuzzo, F\|Varella-Garcia, M\|Finocchiaro, G\|Skokan, M\|Gajapathy, S\|Carnaghi, C\|Rimassa, L\|Rossi, E\|Ligorio, C\|Di Tommaso, L\|Holmes, A J\|Toschi, L\|Tallini, G\|Destro, A\|Roncalli, M\|Santoro, A\|Janne, P A
PMID:	18577988

598.
Journal:	Neoplasia. 2008 Jul;10(7):680-6, 2 p following 686.
Title:	RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A.
Author:	Ahlquist, Terje\|Bottillo, Irene\|Danielsen, Stine A\|Meling, Gunn I\|Rognum, Torleiv O\|Lind, Guro E\|Dallapiccola, Bruno\|Lothe, Ragnhild A
PMID:	18592002

599.
Journal:	Gastroenterology. 2008 Sep;135(3):899-906.
Title:	B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.
Author:	Matos, Paulo\|Oliveira, Carla\|Velho, Sergia\|Goncalves, Vania\|da Costa, Luis Teixiera\|Moyer, Mary Pat\|Seruca, Raquel\|Jordan, Peter
PMID:	18602919

600.
Journal:	Hum Pathol. 2008 Sep;39(9):1301-8.
Title:	Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II.
Author:	Ohta, Miki\|Sugimoto, Takafumi\|Seto, Motoko\|Mohri, Dai\|Asaoka, Yoshinari\|Tada, Motohisa\|Tanaka, Yasuo\|Yamaji, Yutaka\|Kanai, Fumihiko\|Kawabe, Takao\|Omata, Masao
PMID:	18619647

601.
Journal:	Biol Chem. 2008 Jun;389(6):757-64.
Title:	Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells.
Author:	Henkhaus, Rebecca S\|Gerner, Eugene W\|Ignatenko, Natalia A
PMID:	18627290

602.
Journal:	Am J Clin Pathol. 2008 Aug;130(2):247-53.
Title:	High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer.
Author:	Simi, Lisa\|Pratesi, Nicola\|Vignoli, Marina\|Sestini, Roberta\|Cianchi, Fabio\|Valanzano, Rosa\|Nobili, Stefania\|Mini, Enrico\|Pazzagli, Mario\|Orlando, Claudio
PMID:	18628094

603.
Journal:	BMC Cancer. 2008 Jul 27;8:213.
Title:	Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer?
Author:	Kristensen, Annette Torgunrud\|Wiig, Johan N\|Larsen, Stein G\|Giercksky, Karl-Erik\|Ekstrom, Per O
PMID:	18655729

604.
Journal:	Pol J Pathol. 2008;59(2):93-6.
Title:	KRAS mutation profile in colorectal carcinoma and novel mutation--internal tandem duplication in KRAS.
Author:	Wojcik, Piotr\|Kulig, Jan\|Okon, Krzysztof\|Zazula, Monika\|Mozdzioch, Ilona\|Niepsuj, Anna\|Stachura, Jerzy
PMID:	18669174

605.
Journal:	Gene. 2008 Nov 1;423(2):188-93.
Title:	Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1.
Author:	Zhao, Yan\|Miyashita, Kaname\|Ando, Takayuki\|Kakeji, Yoshihiro\|Yamanaka, Takeharu\|Taguchi, Kenichi\|Ushijima, Toshikazu\|Oda, Shinya\|Maehara, Yoshihiko
PMID:	18692554

606.
Journal:	Toxicol Appl Pharmacol. 2008 Nov 1;232(3):408-17.
Title:	Reciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3.
Author:	Zeliadt, Nicholette A\|Mauro, Laura J\|Wattenberg, Elizabeth V
PMID:	18771677

607.
Journal:	BMC Cancer. 2008 Sep 9;8:255.
Title:	BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
Author:	Velho, Sergia\|Moutinho, Catia\|Cirnes, Luis\|Albuquerque, Cristina\|Hamelin, Richard\|Schmitt, Fernando\|Carneiro, Fatima\|Oliveira, Carla\|Seruca, Raquel
PMID:	18782444

608.
Journal:	Clin Cancer Res. 2008 Sep 15;14(18):5869-76.
Title:	Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study.
Author:	Personeni, Nicola\|Fieuws, Steffen\|Piessevaux, Hubert\|De Hertogh, Gert\|De Schutter, Jef\|Biesmans, Bart\|De Roock, Wendy\|Capoen, An\|Debiec-Rychter, Maria\|Van Laethem, Jean-Luc\|Peeters, Marc\|Humblet, Yves\|Van Cutsem, Eric\|Tejpar, Sabine
PMID:	18794099

609.
Journal:	Int J Cancer. 2008 Dec 1;123(11):2587-93.
Title:	Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
Author:	Kim, Yong Ho\|Kakar, Sanjay\|Cun, Lisa\|Deng, Guoren\|Kim, Young S
PMID:	18798261

610.
Journal:	Curr Gastroenterol Rep. 2008 Oct;10(5):490-8.
Title:	Significance of serrated polyps of the colon.
Author:	Groff, Rachel J\|Nash, Russell\|Ahnen, Dennis J
PMID:	18799125

611.
Journal:	Virchows Arch. 2008 Nov;453(5):417-31.
Title:	KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.
Author:	van Krieken, J H J M\|Jung, A\|Kirchner, T\|Carneiro, F\|Seruca, R\|Bosman, F T\|Quirke, P\|Flejou, J F\|Plato Hansen, T\|de Hertogh, G\|Jares, P\|Langner, C\|Hoefler, G\|Ligtenberg, M\|Tiniakos, D\|Tejpar, S\|Bevilacqua, G\|Ensari, A
PMID:	18802721

612.
Journal:	Pathologe. 2008 Nov;29 Suppl 2:200-3.
Title:	[Molecular targets for colon cancer. VEGF, EGFR - and what else?].
Author:	Rocken, C
PMID:	18810446

613.
Journal:	Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title:	CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author:	Lee, Sun\|Cho, Nam-Yun\|Yoo, Eun Joo\|Kim, Jung Ho\|Kang, Gyeong Hoon
PMID:	18834226

614.
Journal:	Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2895-8.
Title:	A prospective study of dietary folate and vitamin B and colon cancer according to microsatellite instability and KRAS mutational status.
Author:	Schernhammer, Eva S\|Giovannuccci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18843035

615.
Journal:	Cancer Res. 2008 Oct 15;68(20):8541-6.
Title:	Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.
Author:	Barault, Ludovic\|Charon-Barra, Celine\|Jooste, Valerie\|de la Vega, Mathilde Funes\|Martin, Laurent\|Roignot, Patrick\|Rat, Patrick\|Bouvier, Anne-Marie\|Laurent-Puig, Pierre\|Faivre, Jean\|Chapusot, Caroline\|Piard, Francoise
PMID:	18922929

616.
Journal:	N Engl J Med. 2008 Oct 23;359(17):1757-65.
Title:	K-ras mutations and benefit from cetuximab in advanced colorectal cancer.
Author:	Karapetis, Christos S\|Khambata-Ford, Shirin\|Jonker, Derek J\|O'Callaghan, Chris J\|Tu, Dongsheng\|Tebbutt, Niall C\|Simes, R John\|Chalchal, Haji\|Shapiro, Jeremy D\|Robitaille, Sonia\|Price, Timothy J\|Shepherd, Lois\|Au, Heather-Jane\|Langer, Christiane\|Moore, Mal
PMID:	18946061

617.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5713-20.
Title:	Cohort study of fatty acid synthase expression and patient survival in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Meyerhardt, Jeffrey A\|Kirkner, Gregory J\|Chan, Andrew T\|Kawasaki, Takako\|Giovannucci, Edward L\|Loda, Massimo\|Fuchs, Charles S
PMID:	18955444

618.
Journal:	BioDrugs. 2008;22(6):403-11.
Title:	Panitumumab: in metastatic colorectal cancer with wild-type KRAS.
Author:	Weber, Juliane\|McCormack, Paul L
PMID:	18998757

619.
Journal:	J Clin Oncol. 2008 Dec 10;26(35):5705-12.
Title:	Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.
Author:	Di Nicolantonio, Federica\|Martini, Miriam\|Molinari, Francesca\|Sartore-Bianchi, Andrea\|Arena, Sabrina\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19001320

620.
Journal:	PLoS One. 2008;3(11):e3698.
Title:	Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author:	Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Kure, Shoko\|Kirkner, Gregory J\|Schernhammer, Eva S\|Hazra, Aditi\|Hunter, David J\|Quackenbush, John\|Spiegelman, Donna\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19002263

621.
Journal:	Bull Cancer. 2008 Oct;95(10):931-4.
Title:	[Is it possible to individualize prescription of medical treatment in colorectal cancer? The clinician point of view].
Author:	Ducreux, Michel\|Boige, Valerie\|Malka, David\|Laurent-Puig, Pierre
PMID:	19004722

622.
Journal:	Bull Cancer. 2008 Oct;95(10):935-42.
Title:	[The biological point of view on pharmacogenetics of anticancer agents in colorectal cancer].
Author:	Laurent-Puig, Pierre\|Lievre, Astrid\|Ducreux, Michel\|Loriot, Marie-Anne
PMID:	19004723

623.
Journal:	Bull Cancer. 2008 Oct;95(10):1003-5.
Title:	[Design of new protocols. Role of molecular biology units?].
Author:	Milano, Gerard
PMID:	19004733

624.
Journal:	Tumour Biol. 2008;29(6):343-50.
Title:	Total number of genome alterations in sporadic gastrointestinal cancer inferred from pooled analyses in the literature.
Author:	Nishimura, Takafumi
PMID:	19023234

625.
Journal:	J Natl Cancer Inst. 2008 Dec 3;100(23):1734-8.
Title:	A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Chan, Andrew T\|Schernhammer, Eva S\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19033568

626.
Journal:	Electrophoresis. 2008 Dec;29(23):4751-60.
Title:	Ligase detection reaction for the analysis of point mutations using free-solution conjugate electrophoresis in a polymer microfluidic device.
Author:	Sinville, Rondedrick\|Coyne, Jennifer\|Meagher, Robert J\|Cheng, Yu-Wei\|Barany, Francis\|Barron, Annelise\|Soper, Steven A
PMID:	19053073

627.
Journal:	Oncologist. 2008 Dec;13(12):1270-5.
Title:	High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice.
Author:	Santini, Daniele\|Loupakis, Fotios\|Vincenzi, Bruno\|Floriani, Irene\|Stasi, Irene\|Canestrari, Emanuele\|Rulli, Eliana\|Maltese, Paolo Enrico\|Andreoni, Francesca\|Masi, Gianluca\|Graziano, Francesco\|Baldi, Giacomo Giulio\|Salvatore, Lisa\|Russo, Antonio\|Perrone, Gi
PMID:	19056857

628.
Journal:	Zhonghua Zhong Liu Za Zhi. 2008 Jul;30(7):498-501.
Title:	[Effect of microRNA143 expression on cell proliferation in colonic carcinoma].
Author:	Liu, Hong\|Zhang, Su-Zhan\|Cai, Shan-Rong\|Peng, Jia-Ping\|Zheng, Shu
PMID:	19062714

629.
Journal:	Br J Cancer. 2008 Dec 16;99(12):2100.
Title:	KRAS mutation status in colorectal cancer to predict response to EGFR targeted therapies: the need for a more precise definition.
Author:	Rouleau, E\|Spyratos, F\|Dieumegard, B\|Guinebretiere, J M\|Lidereau, R\|Bieche, I
PMID:	19078954

630.
Journal:	Mol Cancer. 2008 Dec 16;7:92.
Title:	Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.
Author:	Monticone, Massimiliano\|Biollo, Emanuela\|Maffei, Massimo\|Donadini, Alessandra\|Romeo, Francesco\|Storlazzi, Clelia Tiziana\|Giaretti, Walter\|Castagnola, Patrizio
PMID:	19087308

631.
Journal:	Clin Cancer Res. 2008 Dec 15;14(24):8221-7.
Title:	Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.
Author:	Ogino, Shuji\|Kirkner, Gregory J\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Shima, Kaori\|Hazra, Aditi\|Chan, Andrew T\|Dehari, Reiko\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19088039

632.
Journal:	Cancer Treat Rev. 2008;34 Suppl 2:S3-7.
Title:	First-line combination treatment of colorectal cancer with hepatic metastases: choosing a targeted agent.
Author:	Lenz, Heinz-Josef
PMID:	19101405

633.
Journal:	Mol Cancer. 2008 Dec 31;7:94.
Title:	Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author:	Ahlquist, Terje\|Lind, Guro E\|Costa, Vera L\|Meling, Gunn I\|Vatn, Morten\|Hoff, Geir S\|Rognum, Torleiv O\|Skotheim, Rolf I\|Thiis-Evensen, Espen\|Lothe, Ragnhild A
PMID:	19117505

634.
Journal:	Curr Treat Options Oncol. 2008 Dec;9(4-6):357-74.
Title:	The role of targeted therapy in the treatment of advanced colorectal cancer.
Author:	Fakih, Marwan
PMID:	19238551

635.
Journal:	Ther Clin Risk Manag. 2008 Dec;4(6):1221-7.
Title:	Targeting colorectal cancer with anti-epidermal growth factor receptor antibodies: focus on panitumumab.
Author:	Hoda, Daanish\|Simon, George R\|Garrett, Christopher R
PMID:	19337429

636.
Journal:	Gastrointest Cancer Res. 2008 Jul;2(4 Suppl):S20-2.
Title:	Colorectal Cancer Treatment: What's Next? (or: Is There Life After EGFR and VEGF?).
Author:	Saltz, Leonard
PMID:	19343143

637.
Journal:	Clin Adv Hematol Oncol. 2008 Dec;6(12):1-13, 14-6.
Title:	KRAS mutation in metastatic colorectal cancer and its impact on the use of EGFR inhibitors.
Author:	Lenz, Heinz-Josef\|Chu, Edward\|Grothey, Axel
PMID:	19378369

638.
Journal:	J Cancer Epidemiol. 2008;2008:215809.
Title:	Genetic and epigenetic tumor suppressor gene silencing are distinct molecular phenotypes driven by growth promoting mutations in nonsmall cell lung cancer.
Author:	Marsit, Carmen J\|Houseman, E Andres\|Nelson, Heather H\|Kelsey, Karl T
PMID:	20445774

639.
Journal:	Mutat Res. 2009 Jan-Feb;681(1):33-43.
Title:	Use of Comet-FISH in the study of DNA damage and repair: review.
Author:	Glei, Michael\|Hovhannisyan, Galina\|Pool-Zobel, Beatrice L
PMID:	18304859

640.
Journal:	Ann Oncol. 2009 Jan;20(1):84-90.
Title:	PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.
Author:	Perrone, F\|Lampis, A\|Orsenigo, M\|Di Bartolomeo, M\|Gevorgyan, A\|Losa, M\|Frattini, M\|Riva, C\|Andreola, S\|Bajetta, E\|Bertario, L\|Leo, E\|Pierotti, M A\|Pilotti, S
PMID:	18669866

641.
Journal:	Genes Chromosomes Cancer. 2009 Jan;48(1):1-9.
Title:	Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Author:	Sweeney, Carol\|Boucher, Kenneth M\|Samowitz, Wade S\|Wolff, Roger K\|Albertsen, Hans\|Curtin, Karen\|Caan, Bette J\|Slattery, Martha L
PMID:	18767147

642.
Journal:	Gut. 2009 Jan;58(1):90-6.
Title:	CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	18832519

643.
Journal:	J Pathol. 2009 Jan;217(1):42-53.
Title:	Role of Necl-5 in the pathophysiology of colorectal lesions induced by dimethylhydrazine and/or dextran sodium sulphate.
Author:	Abe, A\|Fukui, H\|Fujii, S\|Kono, T\|Mukawa, K\|Yoshitake, N\|Sekikawa, A\|Ichikawa, K\|Tomita, S\|Yamagishi, H\|Imai, Y\|Shinoda, M\|Ishizaki, H\|Tanaka-Okamoto, M\|Kubota, K\|Miyoshi, J\|Takai, Y\|Fujimori, T
PMID:	18973187

644.
Journal:	Cancer Lett. 2009 Feb 18;274(2):266-70.
Title:	Endometrial cancer and somatic G>T KRAS transversion in patients with constitutional MUTYH biallelic mutations.
Author:	Tricarico, Rossella\|Bet, Paola\|Ciambotti, Benedetta\|Di Gregorio, Carmela\|Gatteschi, Beatrice\|Gismondi, Viviana\|Toschi, Benedetta\|Tonelli, Francesco\|Varesco, Liliana\|Genuardi, Maurizio
PMID:	18980800

645.
Journal:	Gastroenterology. 2009 Jan;136(1):206-16.
Title:	Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression.
Author:	Ohta, Miki\|Seto, Motoko\|Ijichi, Hideaki\|Miyabayashi, Koji\|Kudo, Yotaro\|Mohri, Dai\|Asaoka, Yoshinari\|Tada, Motohisa\|Tanaka, Yasuo\|Ikenoue, Tsuneo\|Kanai, Fumihiko\|Kawabe, Takao\|Omata, Masao
PMID:	18992247

646.
Journal:	Mutat Res. 2009 Jan 15;660(1-2):12-21.
Title:	Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
Author:	Slattery, Martha L\|Wolff, Roger K\|Curtin, Karen\|Fitzpatrick, Frank\|Herrick, Jennifer\|Potter, John D\|Caan, Bette J\|Samowitz, Wade S
PMID:	18992263

647.
Journal:	Gastroenterology. 2009 Feb;136(2):459-70.
Title:	High detection rates of colorectal neoplasia by stool DNA testing with a novel digital melt curve assay.
Author:	Zou, Hongzhi\|Taylor, William R\|Harrington, Jonathan J\|Hussain, Fareeda Taher Nazer\|Cao, Xiaoming\|Loprinzi, Charles L\|Levine, Theodore R\|Rex, Douglas K\|Ahnen, Dennis\|Knigge, Kandice L\|Lance, Peter\|Jiang, Xuan\|Smith, David I\|Ahlquist, David A
PMID:	19026650

648.
Journal:	J Clin Oncol. 2009 Jan 1;27(1):158-9; author reply 159.
Title:	KRAS mutations and anti-epidermal growth factor receptor therapy in colorectal cancer with lymph node metastases.
Author:	Velho, Sergia\|Oliveira, Carla\|Seruca, Raquel
PMID:	19047277

649.
Journal:	Am J Surg Pathol. 2009 Apr;33(4):572-82.
Title:	Clinical, pathologic, and molecular features of early-onset colorectal carcinoma.
Author:	Yantiss, Rhonda K\|Goodarzi, Mahmoud\|Zhou, Xi K\|Rennert, Hanna\|Pirog, Edyta C\|Banner, Barbara F\|Chen, Yao-Tseng
PMID:	19047896

650.
Journal:	Pharmacogenomics. 2009 Jan;10(1):1-3.
Title:	Setting future standards for KRAS testing in colorectal cancer.
Author:	van Krieken, Han\|Tol, Jolien
PMID:	19102707

651.
Journal:	Neoplasia. 2009 Jan;11(1):22-31, 6p following 31.
Title:	Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function.
Author:	Lee, Sun-Hye\|Lee, Su-Jin\|Jung, Yeon Sang\|Xu, Yongbin\|Kang, Ho Sung\|Ha, Nam-Chul\|Park, Bum-Joon
PMID:	19107228

652.
Journal:	Cancer Treat Rev. 2009 May;35(3):262-71.
Title:	Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR.
Author:	Heinemann, Volker\|Stintzing, Sebastian\|Kirchner, Thomas\|Boeck, Stefan\|Jung, Andreas
PMID:	19117687

653.
Journal:	J Clin Oncol. 2009 Mar 1;27(7):1130-6.
Title:	KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection.
Author:	Jimeno, Antonio\|Messersmith, Wells A\|Hirsch, Fred R\|Franklin, Wilbur A\|Eckhardt, S Gail
PMID:	19124802

654.
Journal:	Oncogene. 2009 Mar 12;28(10):1385-92.
Title:	Role of miR-143 targeting KRAS in colorectal tumorigenesis.
Author:	Chen, X\|Guo, X\|Zhang, H\|Xiang, Y\|Chen, J\|Yin, Y\|Cai, X\|Wang, K\|Wang, G\|Ba, Y\|Zhu, L\|Wang, J\|Yang, R\|Zhang, Y\|Ren, Z\|Zen, K\|Zhang, J\|Zhang, C-Y
PMID:	19137007

655.
Journal:	Oncologist. 2009 Jan;14(1):29-39.
Title:	Anti-epidermal growth factor receptor monotherapy in the treatment of metastatic colorectal cancer: where are we today?
Author:	Peeters, Marc\|Price, Tim\|Van Laethem, Jean-Luc
PMID:	19144681

656.
Journal:	Carcinogenesis. 2009 Mar;30(3):494-9.
Title:	Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B.
Author:	Asaka, Shin-ichi\|Arai, Yoshiko\|Nishimura, Yoji\|Yamaguchi, Kensei\|Ishikubo, Tsutomu\|Yatsuoka, Toshimasa\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	19147861

657.
Journal:	Gan To Kagaku Ryoho. 2009 Jan;36(1):11-4.
Title:	[Biomarker for chemotherapy in patients with colorectal cancer].
Author:	Matsusaka, Satoshi
PMID:	19151559

658.
Journal:	Ann Oncol. 2009 Jul;20(7):1216-22.
Title:	MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
Author:	de Vogel, S\|Weijenberg, M P\|Herman, J G\|Wouters, K A D\|de Goeij, A F P M\|van den Brandt, P A\|de Bruine, A P\|van Engeland, M
PMID:	19164452

659.
Journal:	Gastroenterology. 2009 Apr;136(4):1242-50.
Title:	Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.
Author:	Ogino, Shuji\|Shima, Kaori\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Chen, Li\|Toyoda, Saori\|Kirkner, Gregory J\|Wang, Y Lynn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19186181

660.
Journal:	J Clin Oncol. 2009 Apr 20;27(12):2091-6.
Title:	American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy.
Author:	Allegra, Carmen J\|Jessup, J Milburn\|Somerfield, Mark R\|Hamilton, Stanley R\|Hammond, Elizabeth H\|Hayes, Daniel F\|McAllister, Pamela K\|Morton, Roscoe F\|Schilsky, Richard L
PMID:	19188670

661.
Journal:	Cancer. 2009 Apr 1;115(7):1544-54.
Title:	Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy.
Author:	Peeters, Marc\|Siena, Salvatore\|Van Cutsem, Eric\|Sobrero, Alberto\|Hendlisz, Alain\|Cascinu, Stefano\|Kalofonos, Haralabos\|Devercelli, Giovanna\|Wolf, Michael\|Amado, Rafael G
PMID:	19189371

662.
Journal:	Clin Cancer Res. 2009 Feb 15;15(4):1155-61.
Title:	Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.
Author:	Kumar, Krishan\|Brim, Hassan\|Giardiello, Francis\|Smoot, Duane T\|Nouraie, Mehdi\|Lee, Edward L\|Ashktorab, Hassan
PMID:	19190129

663.
Journal:	Gastroenterology. 2009 May;136(5):1680-8.e7.
Title:	TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.
Author:	Trobridge, Patty\|Knoblaugh, Sue\|Washington, M Kay\|Munoz, Nina M\|Tsuchiya, Karen D\|Rojas, Andres\|Song, Xiaoling\|Ulrich, Cornelia M\|Sasazuki, Takehiko\|Shirasawa, Senji\|Grady, William M
PMID:	19208363

664.
Journal:	Cancer Res. 2009 Mar 1;69(5):1851-7.
Title:	PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.
Author:	Sartore-Bianchi, Andrea\|Martini, Miriam\|Molinari, Francesca\|Veronese, Silvio\|Nichelatti, Michele\|Artale, Salvatore\|Di Nicolantonio, Federica\|Saletti, Piercarlo\|De Dosso, Sara\|Mazzucchelli, Luca\|Frattini, Milo\|Siena, Salvatore\|Bardelli, Alberto
PMID:	19223544

665.
Journal:	J Hematol Oncol. 2009 Feb 23;2:9.
Title:	Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.
Author:	Javle, Milind\|Hsueh, Chung-Tsen
PMID:	19236713

666.
Journal:	J Clin Oncol. 2009 Mar 20;27(9):1477-84.
Title:	PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Chan, Andrew T\|Engelman, Jeffrey A\|Kraft, Peter\|Cantley, Lewis C\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19237633

667.
Journal:	J Clin Oncol. 2009 Apr 10;27(11):1822-8.
Title:	Health-related quality of life in patients with advanced colorectal cancer treated with cetuximab: overall and KRAS-specific results of the NCIC CTG and AGITG CO.17 Trial.
Author:	Au, Heather-Jane\|Karapetis, Christos S\|O'Callaghan, Chris J\|Tu, Dongsheng\|Moore, Malcolm J\|Zalcberg, John R\|Kennecke, Hagen\|Shapiro, Jeremy D\|Koski, Sheryl\|Pavlakis, Nick\|Charpentier, Danielle\|Wyld, David\|Jefford, Michael\|Knight, Gregory J\|Magoski, Nadine
PMID:	19273701

668.
Journal:	Clin Adv Hematol Oncol. 2009 Jan;7(1):45-53, 64.
Title:	K-ras mutations in colorectal cancer: a practice changing discovery.
Author:	Saif, M Wasif\|Shah, Manasi
PMID:	19274041

669.
Journal:	Gastroenterology. 2009 Jul;137(1):176-87.
Title:	Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.
Author:	Li, Vivian S W\|Yuen, Siu Tsan\|Chan, Tsun Leung\|Yan, Helen H N\|Law, Wai Lun\|Yeung, Bonnie H Y\|Chan, Annie S Y\|Tsui, Wai Yin\|So, Samuel\|Chen, Xin\|Leung, Suet Yi
PMID:	19303019

670.
Journal:	Neoplasma. 2009;56(3):275-8.
Title:	Genetic analysis of KRAS mutation status in metastatic colorectal cancer patients.
Author:	Zavodna, K\|Konecny, M\|Krivulcik, T\|Spanik, S\|Behulova, R\|Vizvaryova, M\|Weismanova, E\|Galbavy, S\|Kausitz, J
PMID:	19309232

671.
Journal:	N Engl J Med. 2009 Apr 2;360(14):1408-17.
Title:	Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.
Author:	Van Cutsem, Eric\|Kohne, Claus-Henning\|Hitre, Erika\|Zaluski, Jerzy\|Chang Chien, Chung-Rong\|Makhson, Anatoly\|D'Haens, Geert\|Pinter, Tamas\|Lim, Robert\|Bodoky, Gyorgy\|Roh, Jae Kyung\|Folprecht, Gunnar\|Ruff, Paul\|Stroh, Christopher\|Tejpar, Sabine\|Schlichting, M
PMID:	19339720

672.
Journal:	Clin Exp Metastasis. 2009;26(6):569-87.
Title:	A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.
Author:	Joyce, Tobias\|Cantarella, Daniela\|Isella, Claudio\|Medico, Enzo\|Pintzas, Alexander
PMID:	19340593

673.
Journal:	Cancer Lett. 2009 Aug 28;281(2):162-70.
Title:	Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells.
Author:	Xavier, Cristina P R\|Lima, Cristovao F\|Preto, Ana\|Seruca, Raquel\|Fernandes-Ferreira, Manuel\|Pereira-Wilson, Cristina
PMID:	19344998

674.
Journal:	Am J Ther. 2009 Nov-Dec;16(6):554-61.
Title:	KRAS mutational status as a predictor of epidermal growth factor receptor inhibitor efficacy in colorectal cancer.
Author:	Baynes, Roy D\|Gansert, Jennifer
PMID:	19352138

675.
Journal:	J Clin Immunol. 2009 Jul;29(4):545-54.
Title:	Association of MICA-TM and MICB C1_2_A microsatellite polymorphisms with tumor progression in patients with colorectal cancer.
Author:	Kopp, R\|Glas, J\|Lau-Werner, U\|Albert, E D\|Weiss, E H
PMID:	19353249

676.
Journal:	BMC Cancer. 2009 Apr 9;9:111.
Title:	KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay.
Author:	Auner, Veronika\|Kriegshauser, Gernot\|Tong, Dan\|Horvat, Reinhard\|Reinthaller, Alexander\|Mustea, Alexander\|Zeillinger, Robert
PMID:	19358724

677.
Journal:	Carcinogenesis. 2009 Jun;30(6):1016-23.
Title:	Lung tumor promotion by curcumin.
Author:	Dance-Barnes, Stephanie T\|Kock, Nancy D\|Moore, Joseph E\|Lin, Elaine Y\|Mosley, Libyadda J\|D'Agostino, Ralph B Jr\|McCoy, Thomas P\|Townsend, Alan J\|Miller, Mark Steven
PMID:	19359593

678.
Journal:	Expert Opin Biol Ther. 2009 May;9(5):565-77.
Title:	KRAS mutations and sensitivity to anti-EGFR monoclonal antibodies in metastatic colorectal carcinoma: an open issue.
Author:	Silvestris, Nicola\|Tommasi, Stefania\|Santini, Daniele\|Russo, Antonio\|Simone, Gianni\|Petriella, Daniela\|Maiello, Evaristo\|Tonini, Giuseppe\|Colucci, Giuseppe
PMID:	19368524

679.
Journal:	Mol Cancer Ther. 2009 Apr;8(4):834-43.
Title:	KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer.
Author:	Yeh, Jen Jen\|Routh, Elizabeth D\|Rubinas, Tara\|Peacock, Janie\|Martin, Timothy D\|Shen, Xiang Jun\|Sandler, Robert S\|Kim, Hong Jin\|Keku, Temitope O\|Der, Channing J
PMID:	19372556

680.
Journal:	Gan To Kagaku Ryoho. 2009 Apr;36(4):557-66.
Title:	[Molecular targeted therapy in colorectal cancer and its resistance].
Author:	Shitara, Kohei\|Muro, Kei
PMID:	19381027

681.
Journal:	J Hematol Oncol. 2009 Apr 22;2:18.
Title:	Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy.
Author:	Chang, David Z\|Kumar, Vikas\|Ma, Ying\|Li, Kuiyuan\|Kopetz, Scott
PMID:	19386128

682.
Journal:	Cancer J. 2009 Mar-Apr;15(2):110-3.
Title:	KRAS mutations and susceptibility to cetuximab and panitumumab in colorectal cancer.
Author:	Jimeno, Antonio\|Messersmith, Wells A\|Hirsch, Fred R\|Franklin, Wilbur A\|Eckhardt, S Gail
PMID:	19390304

683.
Journal:	Oncologist. 2009 May;14(5):478-88.
Title:	Chemotherapy with targeted agents for the treatment of metastatic colorectal cancer.
Author:	Kohne, Claus-Henning\|Lenz, Heinz-Josef
PMID:	19411318

684.
Journal:	Neoplasia. 2009 May;11(5):418-25.
Title:	Aurora-A expression is independently associated with chromosomal instability in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Toyoda, Saori\|Kirkner, Gregory J\|Goel, Ajay\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19412426

685.
Journal:	Invest Clin. 2009 Mar;50(1):55-63.
Title:	[Frequency and clinicopathological associations of K-ras mutations in Venezuelan patients with colo-rectal cancer].
Author:	Estrada, Pedro\|Rojas-Atencio, Alicia\|Zabala, William\|Borjas, Lisbeth\|Soca, Lazaro\|Urdaneta, Karelis\|Alvarez-Nava, Francisco\|Canizales, Jenny\|Rojas, Janeth\|Soto, Marisol
PMID:	19418727

686.
Journal:	Int J Oncol. 2009 Jun;34(6):1541-7.
Title:	Analysis of a correlation between the BRAF V600E mutation and abnormal DNA mismatch repair in patients with sporadic endometrial cancer.
Author:	Kawaguchi, Makiko\|Yanokura, Megumi\|Banno, Kouji\|Kobayashi, Yusuke\|Kuwabara, Yoshiko\|Kobayashi, Maya\|Nomura, Hiroyuki\|Hirasawa, Akira\|Susumu, Nobuyuki\|Aoki, Daisuke
PMID:	19424571

687.
Journal:	Diagn Mol Pathol. 2009 Jun;18(2):62-71.
Title:	Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.
Author:	Packham, Deborah\|Ward, Robyn L\|Ap Lin, Vita\|Hawkins, Nicholas J\|Hitchins, Megan P
PMID:	19430299

688.
Journal:	Mod Pathol. 2009 Jul;22(7):922-32.
Title:	SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Firestein, Ron\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19430421

689.
Journal:	BMC Cancer. 2009 May 13;9:145.
Title:	A gene expression predictor of response to EGFR-targeted therapy stratifies progression-free survival to cetuximab in KRAS wild-type metastatic colorectal cancer.
Author:	Balko, Justin M\|Black, Esther P
PMID:	19439077

690.
Journal:	Mutat Res. 2009 Jun-Jul;677(1-2):27-32.
Title:	Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes.
Author:	Hu, Ying\|Le Leu, Richard K\|Young, Graeme P
PMID:	19442760

691.
Journal:	J Chromatogr A. 2009 Jun 26;1216(26):5147-54.
Title:	Genotyping of K-ras codons 12 and 13 mutations in colorectal cancer by capillary electrophoresis.
Author:	Chen, Yen-Ling\|Chang, Ya-Sian\|Chang, Jan-Gowth\|Wu, Shou-Mei
PMID:	19450806

692.
Journal:	Biosens Bioelectron. 2009 Jul 15;24(11):3306-10.
Title:	A novel mutant allele specific amplification and electrochemiluminescence method for the detection of point mutation in clinical samples.
Author:	Zhu, Debin\|Xing, Da\|Tang, Yabing\|Zhang, Lan
PMID:	19450969

693.
Journal:	Int J Cancer. 2009 Oct 1;125(7):1698-704.
Title:	Tumor markers and rectal cancer: support for an inflammation-related pathway.
Author:	Slattery, Martha L\|Wolff, Roger K\|Herrick, Jennifer\|Caan, Bette J\|Samowitz, Wade
PMID:	19452524

694.
Journal:	Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title:	DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Baba, Yoshifumi\|Kirkner, Gregory J\|Chen, Li\|Gokhale, Sumita\|Hazra, Aditi\|Spiegelman, Donna\|Giovannucci, Edward L\|Jaenisch, Rudolf\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19470733

695.
Journal:	Dtsch Arztebl Int. 2009 Mar;106(12):202-6.
Title:	The treatment of colorectal carcinoma with monoclonal antibodies: the importance of KRAS mutation analysis and EGFR status.
Author:	Stintzing, Sebastian\|Heinemann, Volker\|Moosmann, Nicolas\|Hiddemann, Wolfgang\|Jung, Andreas\|Kirchner, Thomas
PMID:	19471640

696.
Journal:	Gut. 2009 Sep;58(9):1234-41.
Title:	Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
Author:	Seth, R\|Crook, S\|Ibrahem, S\|Fadhil, W\|Jackson, D\|Ilyas, M
PMID:	19474002

697.
Journal:	Cell Oncol. 2009;31(3):161-7.
Title:	A fast, sensitive and accurate high resolution melting (HRM) technology-based assay to screen for common K-ras mutations.
Author:	Kramer, D\|Thunnissen, F B\|Gallegos-Ruiz, M I\|Smit, E F\|Postmus, P E\|Meijer, C J L M\|Snijders, P J F\|Heideman, D A M
PMID:	19478384

698.
Journal:	Nat Rev Clin Oncol. 2009 Jun;6(6):306-7.
Title:	Genetics: Predictive value of KRAS mutations in chemoresistant CRC.
Author:	Lievre, Astrid\|Laurent-Puig, Pierre
PMID:	19483733

699.
Journal:	PLoS One. 2009 May 27;4(5):e5717.
Title:	Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors.
Author:	Jaiswal, Bijay S\|Janakiraman, Vasantharajan\|Kljavin, Noelyn M\|Eastham-Anderson, Jeffrey\|Cupp, James E\|Liang, Yuxin\|Davis, David P\|Hoeflich, Klaus P\|Seshagiri, Somasekar
PMID:	19492075

700.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title:	A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author:	Ogino, Shuji\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Wolpin, Brian M\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19505918

701.
Journal:	Am J Gastroenterol. 2009 Aug;104(8):2047-56.
Title:	A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Kure, Shoko\|Shima, Kaori\|Irahara, Natsumi\|Toyoda, Saori\|Chen, Li\|Kirkner, Gregory J\|Wolpin, Brian M\|Chan, Andrew T\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19513025

702.
Journal:	Cancer. 2009 Aug 15;115(16):3609-17.
Title:	Assessment of K-ras mutation: a step toward personalized medicine for patients with colorectal cancer.
Author:	Jiang, Yixing\|Kimchi, Eric T\|Staveley-O'Carroll, Kevin F\|Cheng, Hua\|Ajani, Jaffer A
PMID:	19526592

703.
Journal:	BMC Cancer. 2009 Jun 15;9:184.
Title:	Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas.
Author:	Nielsen, Maartje\|de Miranda, Noel F C C\|van Puijenbroek, Marjo\|Jordanova, Ekaterina S\|Middeldorp, Anneke\|van Wezel, Tom\|van Eijk, Ronald\|Tops, Carli M J\|Vasen, Hans F A\|Hes, Frederik J\|Morreau, Hans
PMID:	19527492

704.
Journal:	Nat Rev Cancer. 2009 Jul;9(7):489-99.
Title:	Genetic prognostic and predictive markers in colorectal cancer.
Author:	Walther, Axel\|Johnstone, Elaine\|Swanton, Charles\|Midgley, Rachel\|Tomlinson, Ian\|Kerr, David
PMID:	19536109

705.
Journal:	Mol Diagn Ther. 2009;13(2):103-14.
Title:	Clinical biomarkers in oncology: focus on colorectal cancer.
Author:	De Roock, Wendy\|Biesmans, Bart\|De Schutter, Jef\|Tejpar, Sabine
PMID:	19537845

706.
Journal:	Gan To Kagaku Ryoho. 2009 Jun;36(6):1003-6.
Title:	[Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
Author:	Yoda, Yusuke\|Yoshino, Takayuki\|Kadowaki, Shigenori\|Bando, Hideaki\|Okano, Susumu\|Fukushima, Hiraku\|Fuse, Nozomu\|Tahara, Makoto\|Doi, Toshihiko\|Ohtsu, Atsushi
PMID:	19542725

707.
Journal:	Adv Anat Pathol. 2009 Jul;16(4):196-203.
Title:	KRAS mutation testing in colorectal cancer.
Author:	Plesec, Thomas P\|Hunt, Jennifer L
PMID:	19546608

708.
Journal:	Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
Title:	A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Kure, Shoko\|Shima, Kaori\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19549773

709.
Journal:	Int J Cancer. 2009 Dec 15;125(12):2783-91.
Title:	Endogenous expression of the sodium iodide symporter mediates uptake of iodide in murine models of colorectal carcinoma.
Author:	Gaertner, Florian C\|Rohde, Franziska\|Mueller, Jan\|Blechert, Birgit\|Janssen, Klaus-Peter\|Essler, Markus
PMID:	19569179

710.
Journal:	Dis Colon Rectum. 2009 Jul;52(7):1304-11.
Title:	A comparison of colon and rectal somatic DNA alterations.
Author:	Slattery, Martha L\|Curtin, Karen\|Wolff, Roger K\|Boucher, Kenneth M\|Sweeney, Carol\|Edwards, Sandra\|Caan, Bette J\|Samowitz, Wade
PMID:	19571709

711.
Journal:	Indian J Cancer. 2009 Jul-Sep;46(3):219-25.
Title:	Mutation pattern of K-ras gene in colorectal cancer patients of Kashmir: a report.
Author:	Sameer, A S\|Chowdhri, N A\|Abdullah, S\|Shah, Z A\|Siddiqi, M A
PMID:	19574674

712.
Journal:	Mutat Res. 2009 Nov 2;670(1-2):96-8.
Title:	Genetic pathways to colorectal cancer.
Author:	Lea, Isabel A\|Jackson, Marcus A\|Dunnick, June K
PMID:	19576232

713.
Journal:	Magy Onkol. 2009 Jun;53(2):135-42.
Title:	[Panitumumab-treatment of metastatic colorectal cancer].
Author:	Piko, Bela
PMID:	19581179

714.
Journal:	JOP. 2009 Jul 6;10(4):357-60.
Title:	Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
Author:	Strimpakos, Alexios S\|Syrigos, Kostas N\|Saif, Muhammad Wasif
PMID:	19581734

715.
Journal:	Dis Colon Rectum. 2009 Jun;52(6):1039-45.
Title:	Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas.
Author:	Kalady, Matthew F\|Sanchez, Julian A\|Manilich, Elena\|Hammel, Jeff\|Casey, Graham\|Church, James M
PMID:	19581844

716.
Journal:	Langenbecks Arch Surg. 2009 Nov;394(6):973-83.
Title:	Treatment for colorectal liver metastases: a review.
Author:	Shimada, Hiroshi\|Tanaka, Kuniya\|Endou, Itaru\|Ichikawa, Yasushi
PMID:	19582473

717.
Journal:	Clin Cancer Res. 2009 Jul 15;15(14):4665-73.
Title:	Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Freed, Ellen\|Irahara, Natsumi\|Philips, Juliet\|Meyerhardt, Jeffrey A\|Hornick, Jason L\|Shivdasani, Ramesh A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19584150

718.
Journal:	Clin Cancer Res. 2009 Jul 15;15(14):4531-7.
Title:	Down-regulation of epidermal growth factor receptor by selective expansion of a 5'-end regulatory dinucleotide repeat in colon cancer with microsatellite instability.
Author:	Baranovskaya, Svetlana\|Martin, Yolanda\|Alonso, Sergio\|Pisarchuk, Ksenia L\|Falchetti, Mario\|Dai, Yuichi\|Khaldoyanidi, Sophia\|Krajewski, Stan\|Novikova, Inna\|Sidorenko, Yuri S\|Perucho, Manuel\|Malkhosyan, Sergei R
PMID:	19584170

719.
Journal:	J Clin Oncol. 2009 Aug 20;27(24):4027-34.
Title:	Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges.
Author:	Mandrekar, Sumithra J\|Sargent, Daniel J
PMID:	19597023

720.
Journal:	Nat Rev Clin Oncol. 2009 Sep;6(9):528-34.
Title:	Are RAS mutations predictive markers of resistance to standard chemotherapy?
Author:	Loriot, Yohann\|Mordant, Pierre\|Deutsch, Eric\|Olaussen, Ken Andre\|Soria, Jean-Charles
PMID:	19597509

721.
Journal:	Br J Cancer. 2009 Aug 18;101(4):715-21.
Title:	KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.
Author:	Loupakis, F\|Ruzzo, A\|Cremolini, C\|Vincenzi, B\|Salvatore, L\|Santini, D\|Masi, G\|Stasi, I\|Canestrari, E\|Rulli, E\|Floriani, I\|Bencardino, K\|Galluccio, N\|Catalano, V\|Tonini, G\|Magnani, M\|Fontanini, G\|Basolo, F\|Falcone, A\|Graziano, F
PMID:	19603018

722.
Journal:	Gan To Kagaku Ryoho. 2009 Jul;36(7):1063-6.
Title:	[Status of components in EGFR-related signal transduction as predictive markers for anti-EGFR antibody therapy in colorectal cancer treatment].
Author:	Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Ishioka, Chikashi
PMID:	19620792

723.
Journal:	Surgery. 2009 Aug;146(2):227-31.
Title:	Genetic and molecular diversity of colon cancer hepatic metastases.
Author:	Messick, Craig A\|Sanchez, Julian\|Dejulius, Kathryn L\|Church, James M\|Kalady, Matthew F
PMID:	19628078

724.
Journal:	Clin Colorectal Cancer. 2009 Jul;8(3):135-40.
Title:	KRAS testing in metastatic colorectal cancer: implications on the use of biologic agents.
Author:	Bekaii-Saab, Tanios
PMID:	19632927

725.
Journal:	Nat Rev Clin Oncol. 2009 Sep;6(9):519-27.
Title:	Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.
Author:	Normanno, Nicola\|Tejpar, Sabine\|Morgillo, Floriana\|De Luca, Antonella\|Van Cutsem, Eric\|Ciardiello, Fortunato
PMID:	19636327

726.
Journal:	Int J Cancer. 2009 Nov 15;125(10):2332-41.
Title:	Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.
Author:	Balmanno, Kathryn\|Chell, Simon D\|Gillings, Annette S\|Hayat, Shaista\|Cook, Simon J
PMID:	19637312

727.
Journal:	Int J Cancer. 2009 Nov 1;125(9):2127-35.
Title:	TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Author:	Oikonomou, Eftychia\|Kosmidou, Vivian\|Katseli, Anastasia\|Kothonidis, Konstantinos\|Mourtzoukou, Despina\|Kontogeorgos, George\|Andera, Ladislav\|Zografos, Georgios\|Pintzas, Alexander
PMID:	19637313

728.
Journal:	J Mol Diagn. 2009 Sep;11(5):381-9.
Title:	Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology.
Author:	Snozek, Christine L H\|O'Kane, Dennis J\|Algeciras-Schimnich, Alicia
PMID:	19644023

729.
Journal:	Anticancer Res. 2009 Aug;29(8):3369-74.
Title:	A novel K-ras mutation in colorectal cancer. A case report and literature review.
Author:	Palmirotta, Raffaele\|Savonarola, Annalisa\|Formica, Vincenzo\|Ludovici, Giorgia\|Del Monte, Girolamo\|Roselli, Mario\|Guadagni, Fiorella
PMID:	19661358

730.
Journal:	Science. 2009 Sep 18;325(5947):1555-9.
Title:	Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Author:	Yun, Jihye\|Rago, Carlo\|Cheong, Ian\|Pagliarini, Ray\|Angenendt, Philipp\|Rajagopalan, Harith\|Schmidt, Kerstin\|Willson, James K V\|Markowitz, Sandy\|Zhou, Shibin\|Diaz, Luis A Jr\|Velculescu, Victor E\|Lengauer, Christoph\|Kinzler, Kenneth W\|Vogelstein, Bert\|Papado
PMID:	19661383

731.
Journal:	Curr Drug Targets. 2009 Oct;10(10):1033-40.
Title:	Anti-EGFR therapy in colorectal cancer: how to choose the right patient.
Author:	Meriggi, F\|Di Biasi, B\|Abeni, C\|Zaniboni, A
PMID:	19663767

732.
Journal:	J Natl Cancer Inst. 2009 Sep 2;101(17):1182-92.
Title:	Prospective cost-effectiveness analysis of cetuximab in metastatic colorectal cancer: evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 trial.
Author:	Mittmann, Nicole\|Au, Heather-Jane\|Tu, Dongsheng\|O'Callaghan, Christopher J\|Isogai, Pierre K\|Karapetis, Christos S\|Zalcberg, John R\|Evans, William K\|Moore, Malcolm J\|Siddiqui, Jehan\|Findlay, Brian\|Colwell, Bruce\|Simes, John\|Gibbs, Peter\|Links, Matthew\|Tebb
PMID:	19666851

733.
Journal:	Cancer Causes Control. 2009 Nov;20(9):1763-8.
Title:	Microsatellite instability and survival in rectal cancer.
Author:	Samowitz, Wade S\|Curtin, Karen\|Wolff, Roger K\|Tripp, Sheryl R\|Caan, Bette J\|Slattery, Martha L
PMID:	19669908

734.
Journal:	Zhonghua Yi Xue Za Zhi. 2009 May 26;89(20):1387-90.
Title:	[Efficacy of cetuximab in therapy of metastatic colorectal cancer: a system evaluation].
Author:	Hou, Sheng-huai\|Liang, Xiao-bo\|Bai, Wen-qi\|Yang, Jun\|Yan, Dong\|Zhang, Xin\|Wang, Li-chun
PMID:	19671328

735.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1390-8.
Title:	Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha.
Author:	Mori, Akira\|Moser, Christian\|Lang, Sven A\|Hackl, Christina\|Gottfried, Eva\|Kreutz, Marina\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	19671674

736.
Journal:	Mol Cancer Res. 2009 Aug;7(8):1244-52.
Title:	Oncogenic activating mutations are associated with local copy gain.
Author:	Modrek, Barmak\|Ge, Lin\|Pandita, Ajay\|Lin, Eva\|Mohan, Sankar\|Yue, Peng\|Guerrero, Steve\|Lin, William M\|Pham, Thinh\|Modrusan, Zora\|Seshagiri, Somasekar\|Stern, Howard M\|Waring, Paul\|Garraway, Levi A\|Chant, John\|Stokoe, David\|Cavet, Guy
PMID:	19671679

737.
Journal:	Genes Chromosomes Cancer. 2009 Nov;48(11):953-62.
Title:	Integrative approach for prioritizing cancer genes in sporadic colon cancer.
Author:	Reid, James F\|Gariboldi, Manuela\|Sokolova, Viktorija\|Capobianco, Patrizia\|Lampis, Andrea\|Perrone, Federica\|Signoroni, Stefano\|Costa, Aurora\|Leo, Ermanno\|Pilotti, Silvana\|Pierotti, Marco A
PMID:	19672874

738.
Journal:	BMC Cancer. 2009 Aug 13;9:282.
Title:	Presence of activating KRAS mutations correlates significantly with expression of tumour suppressor genes DCN and TPM1 in colorectal cancer.
Author:	Mlakar, Vid\|Berginc, Gasper\|Volavsek, Metka\|Stor, Zdravko\|Rems, Miran\|Glavac, Damjan
PMID:	19678923

739.
Journal:	Cancer Epidemiol. 2009 Aug;33(2):123-9.
Title:	A gene marker panel covering the Wnt and the Ras-Raf-MEK-MAPK signalling pathways allows to detect gene mutations in 80% of early (UICC I) colon cancer stages in humans.
Author:	Scholtka, Bettina\|Schneider, Mandy\|Melcher, Ralph\|Katzenberger, Tiemo\|Friedrich, Daniela\|Berghof-Jager, Kornelia\|Scheppach, Wolfgang\|Steinberg, Pablo
PMID:	19679059

740.
Journal:	Pathol Res Pract. 2009;205(12):858-62.
Title:	Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer.
Author:	Neumann, Jens\|Zeindl-Eberhart, Evelyn\|Kirchner, Thomas\|Jung, Andreas
PMID:	19679400

741.
Journal:	Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title:	A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author:	Nosho, Katsuhiko\|Kure, Shoko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Spiegelman, Donna\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19686742

742.
Journal:	Clin Cancer Res. 2009 Sep 1;15(17):5528-33.
Title:	Tissue biomarker development in a multicentre trial context: a feasibility study on the PETACC3 stage II and III colon cancer adjuvant treatment trial.
Author:	Bosman, Fred T\|Yan, Pu\|Tejpar, Sabine\|Fiocca, Roberto\|Van Cutsem, Eric\|Kennedy, Richard D\|Dietrich, Daniel\|Roth, Arnaud
PMID:	19690194

743.
Journal:	J Clin Invest. 2009 Sep;119(9):2702-13.
Title:	Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Author:	Lee, Daekee\|Yu, Ming\|Lee, Eunjung\|Kim, Hyunok\|Yang, Yanan\|Kim, Kyoungmi\|Pannicia, Christina\|Kurie, Jonathan M\|Threadgill, David W
PMID:	19690388

744.
Journal:	Rev Med Suisse. 2009 Jul 15;5(211):1513-8.
Title:	[Predictive biomarkers in colorectal cancer].
Author:	Bosman, Fred T
PMID:	19694362

745.
Journal:	J Clin Oncol. 2009 Sep 20;27(27):4591-8.
Title:	Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Kirkner, Gregory J\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19704056

746.
Journal:	Gastroenterol Clin Biol. 2009 Aug-Sep;33(8-9):672-80.
Title:	[Targeted biotherapy: a revolution in the management of patients with colorectal cancer?].
Author:	Rougier, P\|Mitry, E
PMID:	19717258

747.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21.
Title:	p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Shima, Kaori\|Baba, Yoshifumi\|Irahara, Natsumi\|Kirkner, Gregory J\|Hazra, Aditi\|De Vivo, Immaculata\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19723919

748.
Journal:	Mod Pathol. 2009 Dec;22(12):1588-99.
Title:	MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.
Author:	Hawkins, Nicholas J\|Lee, James H-F\|Wong, Justin J-L\|Kwok, Chau-To\|Ward, Robyn L\|Hitchins, Megan P
PMID:	19734844

749.
Journal:	Cancer Prev Res (Phila). 2009 Sep;2(9):814-22.
Title:	Concordant DNA methylation in synchronous colorectal carcinomas.
Author:	Konishi, Kazuo\|Shen, Lanlan\|Jelinek, Jaroslav\|Watanabe, Yoshiyuki\|Ahmed, Saira\|Kaneko, Kazuhiro\|Kogo, Mari\|Takano, Toshihumi\|Imawari, Michio\|Hamilton, Stanley R\|Issa, Jean-Pierre J
PMID:	19737982

750.
Journal:	J Clin Oncol. 2009 Oct 20;27(30):5068-74.
Title:	Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
Author:	Jacobs, Bart\|De Roock, Wendy\|Piessevaux, Hubert\|Van Oirbeek, Robin\|Biesmans, Bart\|De Schutter, Jef\|Fieuws, Steffen\|Vandesompele, Jo\|Peeters, Marc\|Van Laethem, Jean-Luc\|Humblet, Yves\|Penault-Llorca, Frederique\|De Hertogh, Gert\|Laurent-Puig, Pierre\|Van Cuts
PMID:	19738126

751.
Journal:	J Natl Cancer Inst. 2009 Oct 7;101(19):1308-24.
Title:	Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
Author:	Siena, Salvatore\|Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Balfour, Julia\|Bardelli, Alberto
PMID:	19738166

752.
Journal:	Am J Surg Pathol. 2009 Dec;33(12):1823-32.
Title:	Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation.
Author:	Yachida, Shinichi\|Mudali, Shiyama\|Martin, Sherri A\|Montgomery, Elizabeth A\|Iacobuzio-Donahue, Christine A
PMID:	19745699

753.
Journal:	J Int Med Res. 2009 Jul-Aug;37(4):1038-45.
Title:	Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
Author:	Kominami, K\|Nagasaka, T\|Cullings, H M\|Hoshizima, N\|Sasamoto, H\|Young, J\|Leggett, B A\|Tanaka, N\|Matsubara, N
PMID:	19761686

754.
Journal:	J Clin Pathol. 2009 Oct;62(10):886-91.
Title:	Detection of KRAS mutations in colorectal cancer by high-resolution melting analysis.
Author:	Ma, E S K\|Wong, C L P\|Law, F B F\|Chan, W-K\|Siu, D
PMID:	19783717

755.
Journal:	Br J Surg. 2009 Oct;96(10):1196-204.
Title:	Genetic and epigenetic classifications define clinical phenotypes and determine patient outcomes in colorectal cancer.
Author:	Sanchez, J A\|Krumroy, L\|Plummer, S\|Aung, P\|Merkulova, A\|Skacel, M\|DeJulius, K L\|Manilich, E\|Church, J M\|Casey, G\|Kalady, M F
PMID:	19787768

756.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title:	Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author:	Kure, Shoko\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Irahara, Natsumi\|Shima, Kaori\|Ng, Kimmie\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19789368

757.
Journal:	Arch Pathol Lab Med. 2009 Oct;133(10):1600-6.
Title:	The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer.
Author:	Monzon, Federico A\|Ogino, Shuji\|Hammond, M Elizabeth H\|Halling, Kevin C\|Bloom, Kenneth J\|Nikiforova, Marina N
PMID:	19792050

758.
Journal:	Magy Onkol. 2009 Sep;53(3):263-6.
Title:	[Metachronous metastasis from rectal adenocarcinoma to the penis--case report].
Author:	Kuronya, Zsofia\|Bodrogi, Istvan\|Lovey, Jozsef\|Plotar, Vanda\|Manninger, Sandor\|Papai, Zsuzsanna
PMID:	19793691

759.
Journal:	Saudi J Gastroenterol. 2009 Oct-Dec;15(4):217-9.
Title:	KRAS and TP53 mutations in colorectal carcinoma.
Author:	Al-Kuraya, Khawla S
PMID:	19794264

760.
Journal:	Saudi J Gastroenterol. 2009 Oct-Dec;15(4):244-52.
Title:	Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.
Author:	Sameer, A Syed\|ul Rehman, Shakeel\|Pandith, Arshad A\|Syeed, Nidda\|Shah, Zaffar A\|Chowdhri, Nissar A\|Wani, Khursheed A\|Siddiqi, Mushtaq A
PMID:	19794270

761.
Journal:	J Mol Diagn. 2009 Nov;11(6):508-13.
Title:	Sensitive detection of KRAS mutations in archived formalin-fixed paraffin-embedded tissue using mutant-enriched PCR and reverse-hybridization.
Author:	Ausch, Christoph\|Buxhofer-Ausch, Veronika\|Oberkanins, Christian\|Holzer, Barbara\|Minai-Pour, Michael\|Jahn, Stephan\|Dandachi, Nadia\|Zeillinger, Robert\|Kriegshauser, Gernot
PMID:	19797612

762.
Journal:	PLoS One. 2009 Oct 2;4(10):e7287.
Title:	Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Di Nicolantonio, Federica\|Nichelatti, Michele\|Molinari, Francesca\|De Dosso, Sara\|Saletti, Piercarlo\|Martini, Miriam\|Cipani, Tiziana\|Marrapese, Giovanna\|Mazzucchelli, Luca\|Lamba, Simona\|Veronese, Silvio\|Frattini, Milo\|Bardelli, Albe
PMID:	19806185

763.
Journal:	J Mol Diagn. 2009 Nov;11(6):543-52.
Title:	A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting.
Author:	Whitehall, Vicki\|Tran, Kayla\|Umapathy, Aarti\|Grieu, Fabienne\|Hewitt, Chelsee\|Evans, Tiffany-Jane\|Ismail, Tuty\|Li, Wei Qi\|Collins, Peter\|Ravetto, Paul\|Leggett, Barbara\|Salto-Tellez, Manuel\|Soong, Richie\|Fox, Stephen\|Scott, Rodney J\|Dobrovic, Alexander\|Iaco
PMID:	19815694

764.
Journal:	J Pathol. 2009 Dec;219(4):435-45.
Title:	Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma.
Author:	Abubaker, Jehad\|Bavi, Prashant\|Al-Haqawi, Wael\|Sultana, Mehar\|Al-Harbi, Sayer\|Al-Sanea, Nasser\|Abduljabbar, Alaa\|Ashari, Luai H\|Alhomoud, Samar\|Al-Dayel, Fouad\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	19824059

765.
Journal:	Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title:	Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Meyerhardt, Jeffrey A\|Baba, Yoshifumi\|Shima, Kaori\|Glickman, Jonathan N\|Ferrone, Cristina R\|Mino-Kenudson, Mari\|Tanaka, Noriko\|Dranoff, Glenn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19825961

766.
Journal:	Anticancer Drugs. 2009 Nov;20(10):851-5.
Title:	Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities.
Author:	Modjtahedi, Helmout\|Essapen, Sharadah
PMID:	19826350

767.
Journal:	Am J Ther. 2009 Nov-Dec;16(6):477-9.
Title:	Personalized medicine enters the US marketplace: KRAS, anti-EGFR monoclonal antibodies, and colon cancer.
Author:	Lieberman, Ronald
PMID:	19829092

768.
Journal:	BMC Clin Pathol. 2009 Oct 15;9:8.
Title:	Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor.
Author:	Jonsson, Mats\|Ekstrand, Anna\|Edekling, Thomas\|Eberhard, Jakob\|Grabau, Dorthe\|Borg, David\|Nilbert, Mef
PMID:	19832985

769.
Journal:	Internist (Berl). 2009 Nov;50(11):1239-52.
Title:	[Chemotherapy of colorectal cancer].
Author:	Reinacher-Schick, A\|Pohl, M\|Schmiegel, W
PMID:	19838655

770.
Journal:	Cancer Res. 2009 Nov 1;69(21):8499-506.
Title:	Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.
Author:	Kikuchi, Hirotoshi\|Pino, Maria S\|Zeng, Min\|Shirasawa, Senji\|Chung, Daniel C
PMID:	19843849

771.
Journal:	Neoplasia. 2009 Nov;11(11):1116-31.
Title:	BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells.
Author:	Oikonomou, Eftychia\|Makrodouli, Eleni\|Evagelidou, Maria\|Joyce, Tobias\|Probert, Lesley\|Pintzas, Alexander
PMID:	19881948

772.
Journal:	J Clin Oncol. 2009 Dec 10;27(35):5931-7.
Title:	KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial.
Author:	Richman, Susan D\|Seymour, Matthew T\|Chambers, Philip\|Elliott, Faye\|Daly, Catherine L\|Meade, Angela M\|Taylor, Graham\|Barrett, Jennifer H\|Quirke, Philip
PMID:	19884549

773.
Journal:	Clin Cancer Res. 2009 Nov 15;15(22):6956-62.
Title:	PIK3CA mutations predict local recurrences in rectal cancer patients.
Author:	He, Youji\|Van't Veer, Laura J\|Mikolajewska-Hanclich, Izabela\|van Velthuysen, Marie-Louise F\|Zeestraten, Eliane C M\|Nagtegaal, Iris D\|van de Velde, Cornelis J H\|Marijnen, Corrie A M
PMID:	19903786

774.
Journal:	Clin Transl Oncol. 2009 Nov;11(11):737-47.
Title:	Biomarkers and anti-EGFR therapies for KRAS wild-type metastatic colorectal cancer.
Author:	Garcia-Saenz, Jose A\|Sastre, Javier\|Diaz-Rubio Garcia, Eduardo
PMID:	19917537

775.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Nov;12(6):594-7.
Title:	[Effect of KRAS mutation on efficacy of Cetuximab combined with chemotherapy in advanced colorectal cancer patients].
Author:	Pu, Xing-xiang\|Deng, Yan-hong\|Xu, Fei\|Xiao, Jian\|Guo, Hong-qiang\|Huang, He\|Tian, Ying\|He, You-jian\|Lin, Tong-yu
PMID:	19921572

776.
Journal:	Am J Health Syst Pharm. 2009 Dec 1;66(23):2105-12.
Title:	Clinical and economic value of screening for Kras mutations as predictors of response to epidermal growth factor receptor inhibitors.
Author:	Mancl, Erin E\|Kolesar, Jill M\|Vermeulen, Lee C
PMID:	19923311

777.
Journal:	Clin Cancer Res. 2009 Dec 1;15(23):7322-9.
Title:	KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Irahara, Natsumi\|Niedzwiecki, Donna\|Hollis, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Schaefer, Paul\|Whittom, Renaud\|Hantel, Alexander\|Benson, Al B 3rd\|Goldberg, Richard M\|Bertagnolli, Monica M\|Fuchs, Charles S
PMID:	19934290

778.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3384-8.
Title:	Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer.
Author:	Curtin, Karen\|Samowitz, Wade S\|Wolff, Roger K\|Ulrich, Cornelia M\|Caan, Bette J\|Potter, John D\|Slattery, Martha L
PMID:	19959686

779.
Journal:	BMC Cancer. 2009 Dec 12;9:435.
Title:	Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway.
Author:	Tseng, Ya-Shih\|Lee, Jenq-Chang\|Huang, Chi-Ying F\|Liu, Hsiao-Sheng
PMID:	20003375

780.
Journal:	Clin Cancer Res. 2009 Dec 15;15(24):7492-7501.
Title:	Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.
Author:	Banck, Michaela S\|Grothey, Axel
PMID:	20008849

781.
Journal:	PLoS One. 2009 Dec 18;4(12):e8199.
Title:	KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis.
Author:	Cejas, Paloma\|Lopez-Gomez, Miriam\|Aguayo, Cristina\|Madero, Rosario\|de Castro Carpeno, Javier\|Belda-Iniesta, Cristobal\|Barriuso, Jorge\|Moreno Garcia, Victor\|Larrauri, Javier\|Lopez, Rocio\|Casado, Enrique\|Gonzalez-Baron, Manuel\|Feliu, Jaime
PMID:	20020061

782.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S15-22.
Title:	[Technical considerations for KRAS testing in colorectal cancer. The pathologist's point of view].
Author:	Bibeau, F\|Frugier, H\|Denouel, A\|Sabourin, J-C\|Boissiere-Michot, F
PMID:	20034866

783.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S23-30.
Title:	[Prognostic role of KRAS mutation in colorectal cancer].
Author:	Di Fiore, F\|Michel, P
PMID:	20034867

784.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S31-40.
Title:	[Use of anti-EGFR antibodies (cetuximab and panitumumab) in the treatment of metastatic colorectal cancer in KRAS wild type patients].
Author:	Smith, D\|Bosacki, C\|Merrouche, Y
PMID:	20034868

785.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S41-6.
Title:	[Impact of mutational status of KRAS in the care of patients with colorectal cancer metastasis].
Author:	Assenat, E\|Ychou, M
PMID:	20034869

786.
Journal:	Bull Cancer. 2009 Dec;96 Suppl:S47-56.
Title:	[Technical considerations for KRAS testing in colorectal cancer. The biologist's point of view].
Author:	Blons, H\|Laurent-Puig, P
PMID:	20034870

787.
Journal:	Gan To Kagaku Ryoho. 2009 Nov;36(12):2155-7.
Title:	[A case of liver metastasis treated by cetuximab monotherapy with partial response].
Author:	Murata, Kohei\|Ide, Yoshihito\|Nagase, Hirotsugu\|Mukai, Ryota\|Okada, Kazuyuki\|Ota, Hideo\|Maruyama, Kentaro\|Yokouchi, Hideoki\|Hayashi, Masumi\|Tanaka, Shoko\|Oka, Akemi\|Kinuta, Masakatsu
PMID:	20037354

788.
Journal:	Anticancer Res. 2009 Dec;29(12):5077-82.
Title:	Autophagy: novel action of panitumumab in colon cancer.
Author:	Giannopoulou, Efstathia\|Antonacopoulou, Anna\|Matsouka, Panagiota\|Kalofonos, Haralabos P
PMID:	20044619

789.
Journal:	Magy Onkol. 2009 Dec;53(4):361-6.
Title:	[Validation study of KRAS mutation in colorectal cancer].
Author:	Kopper, Laszlo\|Timar, Jozsef
PMID:	20071308

790.
Journal:	Curr Opin Mol Ther. 2009 Dec;11(6):611-22.
Title:	Predictive biomarkers of clinical response to targeted antibodies in colorectal cancer.
Author:	Chua, Wei\|Moore, Melissa M\|Charles, Kellie A\|Clarke, Stephen J
PMID:	20072938

791.
Journal:	Pancreatology. 2009;9(6):793-6.
Title:	MUTYH exon 7 and 13 mutations associated with colorectal cancer (MAP syndrome) are not commonly associated with sporadic pancreatic cancer.
Author:	Smith, Lauren M\|Sharif, Saima\|Brand, Randall\|Fink, Erin\|Lamb, Janette\|Whitcomb, David C
PMID:	20110747

792.
Journal:	Oncology. 2009;77 Suppl 1:57-68.
Title:	The long and winding road to useful predictive factors for anti-EGFR therapy in metastatic colorectal carcinoma: the KRAS/BRAF pathway.
Author:	Russo, Antonio\|Rizzo, Sergio\|Bronte, Giuseppe\|Silvestris, Nicola\|Colucci, Giuseppe\|Gebbia, Nicola\|Bazan, Viviana\|Fulfaro, Fabio
PMID:	20130433

793.
Journal:	Oncology. 2009;77 Suppl 1:69-74.
Title:	The dark side of the moon: the PI3K/PTEN/AKT pathway in colorectal carcinoma.
Author:	Silvestris, Nicola\|Tommasi, Stefania\|Petriella, Daniela\|Santini, Daniele\|Fistola, Ettore\|Russo, Antonio\|Numico, Gianmauro\|Tonini, Giuseppe\|Maiello, Evaristo\|Colucci, Giuseppe
PMID:	20130434

794.
Journal:	J Oncol. 2009;2009:831626.
Title:	Concordance of KRAS/BRAF Mutation Status in Metastatic Colorectal Cancer before and after Anti-EGFR Therapy.
Author:	Gattenlohner, S\|Etschmann, B\|Kunzmann, V\|Thalheimer, A\|Hack, M\|Kleber, G\|Einsele, H\|Germer, C\|Muller-Hermelink, H-K
PMID:	20300583

795.
Journal:	An R Acad Nac Med (Madr). 2009;126(2):243-57; discussion 258-62.
Title:	[Biomarkers and anti-EGFR therapies for KRAS wild-type tumors in metastatic colorectal cancer patients].
Author:	Diaz-Rubio Garcia, Eduardo
PMID:	20432670

796.
Journal:	Onco Targets Ther. 2009 Feb 18;2:161-70.
Title:	Targeting colorectal cancer with anti-epidermal growth factor receptor antibodies: focus on panitumumab.
Author:	Williams, Kerry J\|Lockhart, A Craig
PMID:	20616903

797.
Journal:	J Oncol Pract. 2009 Mar;5(2):71-2.
Title:	ASCO Provisional Clinical Opinion: KRAS, Cetuximab, and Panitumumab-Clinical Implications in Colorectal Cancer.
Author:	Morton, Roscoe F\|Hammond, Elizabeth H
PMID:	20856723

798.
Journal:	Cancer Manag Res. 2009 Jul 23;1:79-88.
Title:	Evolving role of cetuximab in the treatment of colorectal cancer.
Author:	Schuch, Gunter\|Kobold, Sebastian\|Bokemeyer, Carsten
PMID:	21188126

799.
Journal:	Ther Adv Med Oncol. 2009 Sep;1(2):55-68.
Title:	Medical treatment of advanced colorectal cancer in 2009.
Author:	Grothey, Axel
PMID:	21789113

800.
Journal:	Ther Adv Med Oncol. 2009 Nov;1(3):167-81.
Title:	Beyond KRAS: perspectives on new potential markers of intrinsic and acquired resistance to epidermal growth factor receptor inhibitors in metastatic colorectal cancer.
Author:	Loupakis, Fotios\|Cremolini, Chiara\|Fontanini, Gabriella\|Stasi, Irene\|Salvatore, Lisa\|Falcone, Alfredo
PMID:	21789120

801.
Journal:	Clin Cases Miner Bone Metab. 2009 Jan;6(1):17-24.
Title:	Pharmacogenetics: implementing personalized medicine.
Author:	Mini, Enrico\|Nobili, Stefania
PMID:	22461093

802.
Journal:	Per Med. 2009 Mar;6(2):145-157.
Title:	Toward an individualizing therapy for colorectal cancer: the example of the anti-EGFR monoclonal antibodies.
Author:	Lievre, Astrid\|Laurent-Puig, Pierre
PMID:	29788610

803.
Journal:	J Cell Mol Med. 2010 Aug;14(8):2122-31.
Title:	High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue.
Author:	Tol, Jolien\|Dijkstra, Jeroen R\|Vink-Borger, Marianne E\|Nagtegaal, Iris D\|Punt, Cornelis J A\|Van Krieken, Johan H J M\|Ligtenberg, Marjolijn J L
PMID:	19453520

804.
Journal:	Crit Rev Oncol Hematol. 2010 Apr;74(1):16-26.
Title:	Integration of panitumumab into the treatment of colorectal cancer.
Author:	Gravalos, Cristina\|Cassinello, Javier\|Garcia-Alfonso, Pilar\|Jimeno, Antonio
PMID:	19616446

805.
Journal:	Ann Surg Oncol. 2010 Feb;17(2):572-8.
Title:	KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases.
Author:	Nash, Garrett M\|Gimbel, Mark\|Shia, Jinru\|Nathanson, Daniel R\|Ndubuisi, MacKevin I\|Zeng, Zhao-Shi\|Kemeny, Nancy\|Paty, Philip B
PMID:	19727962

806.
Journal:	Fam Cancer. 2010 Jun;9(2):125-9.
Title:	Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.
Author:	Ekstrand, Anna Isinger\|Jonsson, Mats\|Lindblom, Annika\|Borg, Ake\|Nilbert, Mef
PMID:	19731079

807.
Journal:	Int J Cancer. 2010 Jun 15;126(12):2863-73.
Title:	CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival.
Author:	Firestein, Ron\|Shima, Kaori\|Nosho, Katsuhiko\|Irahara, Natsumi\|Baba, Yoshifumi\|Bojarski, Emeric\|Giovannucci, Edward L\|Hahn, William C\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19790197

808.
Journal:	Am J Gastroenterol. 2010 Feb;105(2):420-33.
Title:	Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Kirkner, Gregory J\|Mino-Kenudson, Mari\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	19809407

809.
Journal:	Ann Surg Oncol. 2010 Feb;17(2):416-24.
Title:	KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer.
Author:	Nash, Garrett M\|Gimbel, Mark\|Cohen, Alfred M\|Zeng, Zhao-Shi\|Ndubuisi, Mackevin I\|Nathanson, Daniel R\|Ott, Jurg\|Barany, Francis\|Paty, Philip B
PMID:	19813061

810.
Journal:	Med Oncol. 2010 Dec;27(4):1066-72.
Title:	MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer.
Author:	Paule, Bernard\|Castagne, Vincent\|Picard, Veronique\|Saffroy, Raphael\|Adam, Rene\|Guettier, Catherine\|Farinotti, Robert\|Bonhomme-Faivre, Laurence
PMID:	19862647

811.
Journal:	Clin Biochem. 2010 Feb;43(3):296-301.
Title:	Detection of N-, H-, and KRAS codons 12, 13, and 61 mutations with universal RAS primer multiplex PCR and N-, H-, and KRAS-specific primer extension.
Author:	Chang, Ya-Sian\|Yeh, Kun-Tu\|Hsu, Nicholas C\|Lin, Shu-Hui\|Chang, Tien-Jye\|Chang, Jan-Gowth
PMID:	19879255

812.
Journal:	Methods Mol Biol. 2010;576:341-50.
Title:	The EGFR pathway as an example for genotype: phenotype correlation in tumor genes.
Author:	Mogck, Ulrike\|Goekkurt, Eray\|Stoehlmacher, Jan
PMID:	19882270

813.
Journal:	Int J Cancer. 2010 Jul 15;127(2):367-80.
Title:	Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.
Author:	Zlobec, Inti\|Bihl, Michel P\|Schwarb, Heike\|Terracciano, Luigi\|Lugli, Alessandro
PMID:	19908233

814.
Journal:	Radiother Oncol. 2010 Jan;94(1):76-81.
Title:	KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.
Author:	Gaedcke, Jochen\|Grade, Marian\|Jung, Klaus\|Schirmer, Markus\|Jo, Peter\|Obermeyer, Christoph\|Wolff, Hendrik A\|Herrmann, Markus K\|Beissbarth, Tim\|Becker, Heinz\|Ried, Thomas\|Ghadimi, Michael
PMID:	19913317

815.
Journal:	Br J Cancer. 2010 Jan 5;102(1):151-61.
Title:	Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients.
Author:	Zlobec, I\|Molinari, F\|Kovac, M\|Bihl, M P\|Altermatt, H J\|Diebold, J\|Frick, H\|Germer, M\|Horcic, M\|Montani, M\|Singer, G\|Yurtsever, H\|Zettl, A\|Terracciano, L\|Mazzucchelli, L\|Saletti, P\|Frattini, M\|Heinimann, K\|Lugli, A
PMID:	19935791

816.
Journal:	Ann Surg Oncol. 2010 Apr;17(4):1168-76.
Title:	KRAS mutation in colon cancer: a marker of resistance to EGFR-I therapy.
Author:	Siddiqui, Ahmad D\|Piperdi, Bilal
PMID:	19936839

817.
Journal:	Ann Surg Oncol. 2010 Feb;17(2):624-33.
Title:	Enhancing detection of circulating tumor cells with activating KRAS oncogene in patients with colorectal cancer by weighted chemiluminescent membrane array method.
Author:	Yang, Ming-Je\|Chiu, Hua-Hsien\|Wang, Hwei-Ming\|Yen, Li-Chen\|Tsao, Der-An\|Hsiao, Chao-Peng\|Chen, Yi-Fang\|Wang, Jaw-Yuan\|Lin, Shiu-Ru
PMID:	19937133

818.
Journal:	Am J Clin Oncol. 2010 Oct;33(5):456-60.
Title:	KRAS status in patients with colorectal cancer peritoneal carcinomatosis and its impact on outcome.
Author:	Gillern, Suzanne M\|Chua, Terence C\|Stojadinovic, Alexander\|Esquivel, Jesus
PMID:	19952717

819.
Journal:	Recent Pat Anticancer Drug Discov. 2010 Jun;5(2):142-51.
Title:	Anti-epidermal growth factor receptor antibodies in the treatment of metastatic colorectal cancer.
Author:	Kendall, Anne\|Lord, Rosemary\|Maisey, Nick
PMID:	19954416

820.
Journal:	Hum Mol Genet. 2010 Feb 15;19(4):697-706.
Title:	Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours.
Author:	Velho, Sergia\|Oliveira, Carla\|Paredes, Joana\|Sousa, Sonia\|Leite, Marina\|Matos, Paulo\|Milanezi, Fernanda\|Ribeiro, Ana Sofia\|Mendes, Nuno\|Licastro, Danilo\|Karhu, Auli\|Oliveira, Maria Jose\|Ligtenberg, Marjolijn\|Hamelin, Richard\|Carneiro, Fatima\|Lindblom, Ann
PMID:	19955118

821.
Journal:	Pathologe. 2010 Feb;31(1):16-21.
Title:	[Pathological diagnosis for individualized therapy of colorectal cancer].
Author:	Kirchner, T\|Jung, A
PMID:	19957085

822.
Journal:	J Mol Diagn. 2010 Jan;12(1):35-42.
Title:	KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: comparison of methods and impact of histology.
Author:	Weichert, Wilko\|Schewe, Christiane\|Lehmann, Annika\|Sers, Christine\|Denkert, Carsten\|Budczies, Jan\|Stenzinger, Albrecht\|Joos, Hans\|Landt, Olfert\|Heiser, Volker\|Rocken, Christoph\|Dietel, Manfred
PMID:	20007841

823.
Journal:	J Mol Diagn. 2010 Jan;12(1):43-50.
Title:	KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.
Author:	Franklin, Wilbur A\|Haney, Jerry\|Sugita, Michio\|Bemis, Lynne\|Jimeno, Antonio\|Messersmith, Wells A
PMID:	20007845

824.
Journal:	J Clin Oncol. 2010 Jan 20;28(3):466-74.
Title:	Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.
Author:	Roth, Arnaud D\|Tejpar, Sabine\|Delorenzi, Mauro\|Yan, Pu\|Fiocca, Roberto\|Klingbiel, Dirk\|Dietrich, Daniel\|Biesmans, Bart\|Bodoky, Gyorgy\|Barone, Carlo\|Aranda, Enrique\|Nordlinger, Bernard\|Cisar, Laura\|Labianca, Roberto\|Cunningham, David\|Van Cutsem, Eric\|Bosma
PMID:	20008640

825.
Journal:	Clin Cancer Res. 2010 Jan 1;16(1):21-33.
Title:	Three DNA methylation epigenotypes in human colorectal cancer.
Author:	Yagi, Koichi\|Akagi, Kiwamu\|Hayashi, Hiroshi\|Nagae, Genta\|Tsuji, Shingo\|Isagawa, Takayuki\|Midorikawa, Yutaka\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Seto, Yasuyuki\|Aburatani, Hiroyuki\|Kaneda, Atsushi
PMID:	20028768

826.
Journal:	Ann Surg Oncol. 2010 May;17(5):1429-34.
Title:	KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications.
Author:	Italiano, Antoine\|Hostein, Isabelle\|Soubeyran, Isabelle\|Fabas, Thibault\|Benchimol, Daniel\|Evrard, Serge\|Gugenheim, Jean\|Becouarn, Yves\|Brunet, Rene\|Fonck, Marianne\|Francois, Eric\|Saint-Paul, Marie-Christine\|Pedeutour, Florence
PMID:	20049644

827.
Journal:	Int J Cancer. 2010 Sep 1;127(6):1321-31.
Title:	Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer.
Author:	Perkins, Geraldine\|Lievre, Astrid\|Ramacci, Carole\|Meatchi, Tchao\|de Reynies, Aurelien\|Emile, Jean-Francois\|Boige, Valerie\|Tomasic, Gorana\|Bachet, Jean-Baptiste\|Bibeau, Frederic\|Bouche, Olivier\|Penault-Llorca, Frederique\|Merlin, Jean-Louis\|Laurent-Puig, Pi
PMID:	20049837

828.
Journal:	Diagn Cytopathol. 2010 Dec;38(12):869-73.
Title:	KRAS mutation analysis on cytological specimens of metastatic colo-rectal cancer.
Author:	Troncone, Giancarlo\|Malapelle, Umberto\|Cozzolino, Immacolata\|Palombini, Lucio
PMID:	20049979

829.
Journal:	Ann Surg Oncol. 2010 Jul;17(7):1767-76.
Title:	Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas.
Author:	Kim, Jin C\|Choi, Jin S\|Roh, Seon A\|Cho, Dong H\|Kim, Tae W\|Kim, Yong S
PMID:	20077021

830.
Journal:	Bull Cancer. 2010 Feb;97(2):265-80.
Title:	[Prerequisites to the administration and prevention of adverse effects of chemotherapy in colorectal cancer].
Author:	Bouche, O\|Scaglia, E\|Lagarde, S
PMID:	20080456

831.
Journal:	Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1565-70.
Title:	Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Author:	Hung, Kenneth E\|Maricevich, Marco A\|Richard, Larissa Georgeon\|Chen, Wei Y\|Richardson, Michael P\|Kunin, Alexandra\|Bronson, Roderick T\|Mahmood, Umar\|Kucherlapati, Raju
PMID:	20080688

832.
Journal:	Carcinogenesis. 2010 May;31(5):777-84.
Title:	Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.
Author:	Hashimoto, Yutaka\|Akiyama, Yoshimitsu\|Otsubo, Takeshi\|Shimada, Shu\|Yuasa, Yasuhito
PMID:	20080834

833.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):358-65.
Title:	Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.
Author:	Chung, Christine H\|Seeley, Erin H\|Roder, Heinrich\|Grigorieva, Julia\|Tsypin, Maxim\|Roder, Joanna\|Burtness, Barbara A\|Argiris, Athanassios\|Forastiere, Arlene A\|Gilbert, Jill\|Murphy, Barbara\|Caprioli, Richard M\|Carbone, David P\|Cohen, Ezra E W
PMID:	20086114

834.
Journal:	Curr Cancer Drug Targets. 2010 Feb;10(1):68-79.
Title:	Molecular predictors of efficacy to anti-EGFR agents in colorectal cancer patients.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Canestrari, Emanuele\|Magnani, Mauro
PMID:	20088793

835.
Journal:	PLoS One. 2010 Jan 21;5(1):e8802.
Title:	Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes.
Author:	Lurkin, Irene\|Stoehr, Robert\|Hurst, Carolyn D\|van Tilborg, Angela A G\|Knowles, Margaret A\|Hartmann, Arndt\|Zwarthoff, Ellen C
PMID:	20098682

836.
Journal:	J Clin Oncol. 2010 Mar 1;28(7):1254-61.
Title:	Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer.
Author:	Bardelli, Alberto\|Siena, Salvatore
PMID:	20100961

837.
Journal:	Gastroenterology. 2010 May;138(5):1854-62.
Title:	Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency.
Author:	Goel, Ajay\|Xicola, Rosa M\|Nguyen, Thuy-Phuong\|Doyle, Brian J\|Sohn, Vanessa R\|Bandipalliam, Prathap\|Rozek, Laura S\|Reyes, Josep\|Cordero, Carmen\|Balaguer, Francesc\|Castells, Antoni\|Jover, Rodrigo\|Andreu, Montserrat\|Syngal, Sapna\|Boland, C Richard\|Llor, Xavi
PMID:	20102720

838.
Journal:	Clin Cancer Res. 2010 Feb 1;16(3):790-9.
Title:	Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases.
Author:	Baldus, Stephan E\|Schaefer, Karl-L\|Engers, Rainer\|Hartleb, Dinah\|Stoecklein, Nikolas H\|Gabbert, Helmut E
PMID:	20103678

839.
Journal:	Mol Cancer Ther. 2010 Feb;9(2):450-60.
Title:	A novel E1B-55kD-deleted oncolytic adenovirus carrying mutant KRAS-regulated hdm2 transgene exerts specific antitumor efficacy on colorectal cancer cells.
Author:	Liu, Chin-Cheng\|Liu, Jin-Hwang\|Wu, Suh-Chin\|Yen, Chueh-Chuan\|Chen, Wei-Shone\|Tsai, Ying-Chieh
PMID:	20124454

840.
Journal:	Cancer Res. 2010 Feb 15;70(4):1479-85.
Title:	Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.
Author:	Slattery, Martha L\|Herrick, Jennifer\|Curtin, Karen\|Samowitz, Wade\|Wolff, Roger K\|Caan, Bette J\|Duggan, David\|Potter, John D\|Peters, Ulrike
PMID:	20124488

841.
Journal:	Oncologist. 2010;15(2):157-67.
Title:	Predicting response to EGFR inhibitors in metastatic colorectal cancer: current practice and future directions.
Author:	Shankaran, Veena\|Obel, Jennifer\|Benson, Al B 3rd
PMID:	20133499

842.
Journal:	Int J Cancer. 2010 Dec 1;127(11):2569-75.
Title:	Combined analysis of specific KRAS mutation, BRAF and microsatellite instability identifies prognostic subgroups of sporadic and hereditary colorectal cancer.
Author:	Zlobec, Inti\|Kovac, Michal\|Erzberger, Priska\|Molinari, Francesca\|Bihl, Michel P\|Rufle, Alexander\|Foerster, Anja\|Frattini, Milo\|Terracciano, Luigi\|Heinimann, Karl\|Lugli, Alessandro
PMID:	20162668

843.
Journal:	Cancer Treat Rev. 2010 Feb;36 Suppl 1:S11-4.
Title:	Successful long-term management of a patient with late-stage metastatic colorectal cancer treated with panitumumab.
Author:	Seront, Emmanuel\|Marot, Liliane\|Coche, Emmanuel\|Gala, Jean-Luc\|Sempoux, Christine\|Humblet, Yves
PMID:	20189054

844.
Journal:	BioDrugs. 2010 Apr 1;24(2):131-46.
Title:	Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter.
Author:	Teimoori-Toolabi, Ladan\|Azadmanesh, Kayhan\|Amanzadeh, Amir\|Zeinali, Sirous
PMID:	20199127

845.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title:	PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Goessling, Wolfram\|Chan, Andrew T\|Ng, Kimmie\|Chan, Jennifer A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20200425

846.
Journal:	J Mol Diagn. 2010 May;12(3):292-9.
Title:	A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinoma.
Author:	Angulo, Barbara\|Garcia-Garcia, Elena\|Martinez, Rebeca\|Suarez-Gauthier, Ana\|Conde, Esther\|Hidalgo, Manuel\|Lopez-Rios, Fernando
PMID:	20203003

847.
Journal:	Diagn Cytopathol. 2010 Dec;38(12):932-5.
Title:	Metastasis of colon cancer to the thyroid gland: a case diagnosed on fine-needle aspirate by a combined cytological, immunocytochemical, and molecular approach.
Author:	Cozzolino, Immacolata\|Malapelle, Umberto\|Carlomagno, Chiara\|Palombini, Lucio\|Troncone, Giancarlo
PMID:	20213843

848.
Journal:	World J Gastroenterol. 2010 Mar 14;16(10):1177-87.
Title:	Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer.
Author:	Saridaki, Zacharenia\|Georgoulias, Vassilis\|Souglakos, John
PMID:	20222160

849.
Journal:	Rinsho Byori. 2010 Feb;58(2):169-74.
Title:	[Current update and testing procedures for genetic diagnosis in malignant neoplasm: additional information on pathological tests].
Author:	Funato, Tadao\|Takeda, Mayu
PMID:	20229816

850.
Journal:	BMC Cancer. 2010 Mar 16;10:99.
Title:	Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study.
Author:	Naguib, Adam\|Mitrou, Panagiota N\|Gay, Laura J\|Cooke, James C\|Luben, Robert N\|Ball, Richard Y\|McTaggart, Alison\|Arends, Mark J\|Rodwell, Sheila A
PMID:	20233436

851.
Journal:	BMC Cancer. 2010 Mar 16;10:101.
Title:	A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
Author:	Fumagalli, Debora\|Gavin, Patrick G\|Taniyama, Yusuke\|Kim, Seung-Il\|Choi, Hyun-Joo\|Paik, Soonmyung\|Pogue-Geile, Katherine L
PMID:	20233444

852.
Journal:	Br J Cancer. 2010 Mar 30;102(7):1137-44.
Title:	Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients.
Author:	Montagut, C\|Iglesias, M\|Arumi, M\|Bellosillo, B\|Gallen, M\|Martinez-Fernandez, A\|Martinez-Aviles, L\|Canadas, I\|Dalmases, A\|Moragon, E\|Lema, L\|Serrano, S\|Rovira, A\|Rojo, F\|Bellmunt, J\|Albanell, J
PMID:	20234366

853.
Journal:	Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2010 Feb;32(1):46-50.
Title:	[Effects of K-ras gene mutation on colon cancer cell line Caco-2 metastasis by regulating E-cadherin/beta-catenin/p120 protein complex formation and RhoA protein activity].
Author:	Li, Jing-nan\|Li, Xiao\|Qian, Jia-ming\|Lu, Xin-qing\|Yang, Hong
PMID:	20236587

854.
Journal:	Lakartidningen. 2010 Feb 3-9;107(5):255-9.
Title:	[Mutational analysis of KRAS prior to targeted therapy in colorectal cancer. Quality control of molecular pathological methods in Sweden].
Author:	Enlund, Fredrik\|Helenius, Gisela\|Palmqvist, Richard\|Edsjo, Anders\|Sundstrom, Magnus
PMID:	20297566

855.
Journal:	Mol Cancer. 2010 Mar 18;9:63.
Title:	Kruppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.
Author:	Nandan, Mandayam O\|Ghaleb, Amr M\|McConnell, Beth B\|Patel, Nilesh V\|Robine, Sylvie\|Yang, Vincent W
PMID:	20298593

856.
Journal:	Nat Rev Clin Oncol. 2010 May;7(5):251-65.
Title:	The molecular pathology of cancer.
Author:	Harris, Timothy J R\|McCormick, Frank
PMID:	20351699

857.
Journal:	Br J Cancer. 2010 Apr 13;102(8):1254-64.
Title:	Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.
Author:	de Bruijn, M T\|Raats, D A E\|Hoogwater, F J H\|van Houdt, W J\|Cameron, K\|Medema, J P\|Borel Rinkes, I H M\|Kranenburg, O
PMID:	20354524

858.
Journal:	Cancer Chemother Pharmacol. 2010 Aug;66(3):605-9.
Title:	Acquired KRAS mutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis.
Author:	Bouchahda, Mohamed\|Karaboue, Abdoulaye\|Saffroy, Raphael\|Innominato, Pasquale\|Gorden, Lee\|Guettier, Catherine\|Adam, Rene\|Levi, Francis
PMID:	20361188

859.
Journal:	Biochem Biophys Res Commun. 2010 Apr 23;395(1):158-62.
Title:	The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: a comparison between direct sequencing and real-time PCR.
Author:	Kobunai, Takashi\|Watanabe, Toshiaki\|Yamamoto, Yoko\|Eshima, Kiyoshi
PMID:	20361930

860.
Journal:	Am J Pathol. 2010 May;176(5):2292-301.
Title:	HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Chung, Daniel C\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20363910

861.
Journal:	Arch Pathol Lab Med. 2010 Apr;134(4):620-4.
Title:	KRas and BRaf mutational status analysis from formalin-fixed, paraffin-embedded tissues using multiplex polymerase chain reaction-based assay.
Author:	Jakubauskas, Arturas\|Griskevicius, Laimonas
PMID:	20367313

862.
Journal:	Int J Oncol. 2010 May;36(5):1137-44.
Title:	KRAS mutations in Slovene patients with colorectal cancer: frequency, distribution and correlation with the response to treatment.
Author:	Licar, Alenka\|Cerkovnik, Petra\|Ocvirk, Janja\|Novakovic, Srdjan
PMID:	20372787

863.
Journal:	Curr Colorectal Cancer Rep. 2010 Mar 10;6(2):51-59.
Title:	Genetic and Chemical Models of Colorectal Cancer in Mice.
Author:	Nandan, Mandayam O\|Yang, Vincent W
PMID:	20376303

864.
Journal:	Clin Colorectal Cancer. 2010 Apr;9(2):102-7.
Title:	A phase II trial of FOLFOX6 and cetuximab in the first-line treatment of patients with metastatic colorectal cancer.
Author:	Boccia, Ralph V\|Cosgriff, Thomas M\|Headley, David L\|Badarinath, Suprith\|Dakhil, Shaker R
PMID:	20378504

865.
Journal:	Oncogene. 2010 May 27;29(21):3033-43.
Title:	Oncogenic mutations as predictive factors in colorectal cancer.
Author:	Lievre, A\|Blons, H\|Laurent-Puig, P
PMID:	20383189

866.
Journal:	Cancer Causes Control. 2010 Aug;21(8):1237-45.
Title:	Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes.
Author:	Slattery, Martha L\|Curtin, Karen\|Wolff, Roger K\|Herrick, Jennifer S\|Caan, Bette J\|Samowitz, Wade
PMID:	20383576

867.
Journal:	BMC Cancer. 2010 Apr 13;10:136.
Title:	Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
Author:	Sanchez-Munoz, Alfonso\|Gallego, Elena\|de Luque, Vanessa\|Perez-Rivas, Luis G\|Vicioso, Luis\|Ribelles, Nuria\|Lozano, Jose\|Alba, Emilio
PMID:	20385028

868.
Journal:	Clin Trials. 2010 Oct;7(5):567-73.
Title:	Predictive biomarker validation in practice: lessons from real trials.
Author:	Mandrekar, Sumithra J\|Sargent, Daniel J
PMID:	20392785

869.
Journal:	Expert Rev Anticancer Ther. 2010 Apr;10(4):499-505.
Title:	Panitumumab: a new frontier of target therapy for the treatment of metastatic colorectal cancer.
Author:	Addeo, Raffaele\|Caraglia, Michele\|Cerbone, Domenico\|Frega, Nicola\|Cimmino, Gaetano\|Abbruzzese, Alberto\|Del Prete, Salvatore
PMID:	20397915

870.
Journal:	Diagn Pathol. 2010 Apr 16;5:23.
Title:	A comparability study of 5 commercial KRAS tests.
Author:	Oliner, Kelly\|Juan, Todd\|Suggs, Sid\|Wolf, Michael\|Sarosi, Ildiko\|Freeman, Daniel J\|Gyuris, Tibor\|Baron, Will\|Bakker, Andreas\|Parker, Alex\|Patterson, Scott D
PMID:	20398393

871.
Journal:	Clin Ther. 2010 Mar;32(3):437-53.
Title:	Monoclonal antibodies in the treatment of metastatic colorectal cancer: a review.
Author:	Tol, Jolien\|Punt, Cornelis J A
PMID:	20399983

872.
Journal:	Curr Clin Pharmacol. 2010 Aug;5(3):166-77.
Title:	Molecular targeted therapy in prevalent tumors: learning from the past and future perspectives.
Author:	Metzger-Filho, Otto\|Moulin, Camilo\|Awada, Ahmad
PMID:	20406173

873.
Journal:	Mol Cancer Ther. 2010 May;9(5):1308-17.
Title:	Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Author:	Serova, Maria\|Astorgues-Xerri, Lucile\|Bieche, Ivan\|Albert, Sebastien\|Vidaud, Michel\|Benhadji, Karim A\|Emami, Shahin\|Vidaud, Dominique\|Hammel, Pascal\|Theou-Anton, Nathalie\|Gespach, Christian\|Faivre, Sandrine\|Raymond, Eric
PMID:	20406951

874.
Journal:	Eur J Cancer. 2010 Jul;46(11):1997-2009.
Title:	Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab.
Author:	Tol, Jolien\|Dijkstra, Jeroen R\|Klomp, Marjolein\|Teerenstra, Steven\|Dommerholt, Martin\|Vink-Borger, M Elisa\|van Cleef, Patricia H\|van Krieken, J Han\|Punt, Cornelis J A\|Nagtegaal, Iris D
PMID:	20413299

875.
Journal:	J Mol Diagn. 2010 Jul;12(4):418-24.
Title:	Detection of low-level KRAS mutations using PNA-mediated asymmetric PCR clamping and melting curve analysis with unlabeled probes.
Author:	Oh, Ji Eun\|Lim, Hee Sun\|An, Chang Hyeok\|Jeong, Eun Goo\|Han, Ji Youn\|Lee, Sug Hyung\|Yoo, Nam Jin
PMID:	20413678

876.
Journal:	Cell Oncol. 2010 Jan 1;32(4):245-57.
Title:	Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.
Author:	van Houdt, Winan J\|de Bruijn, Menno T\|Emmink, Benjamin L\|Raats, Danielle\|Hoogwater, Frederik J H\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	20413844

877.
Journal:	Curr Oncol Rep. 2010 May;12(3):160-7.
Title:	KRAS testing and its importance in colorectal cancer.
Author:	Patil, Deepa T\|Fraser, Cory R\|Plesec, Thomas P
PMID:	20425075

878.
Journal:	Recent Pat DNA Gene Seq. 2010 Jun;4(2):86-93.
Title:	Recent patents and advances in genomic biomarker discovery for colorectal cancers.
Author:	Quyun, Chen\|Ye, Zhiyun\|Lin, Sheng-Cai\|Lin, Biaoyang
PMID:	20426761

879.
Journal:	Am J Pathol. 2010 Jun;176(6):2972-85.
Title:	Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization.
Author:	Redente, Elizabeth F\|Dwyer-Nield, Lori D\|Merrick, Daniel T\|Raina, Komal\|Agarwal, Rajesh\|Pao, William\|Rice, Pamela L\|Shroyer, Kenneth R\|Malkinson, Alvin M
PMID:	20431028

880.
Journal:	Nutr Cancer. 2010;62(4):436-42.
Title:	Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors.
Author:	Slattery, Martha L\|Wolff, Roger K\|Herrick, Jennifer S\|Caan, Bette J\|Samowitz, Wade
PMID:	20432164

881.
Journal:	BMC Cancer. 2010 May 5;10:180.
Title:	Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Author:	van Roon, Eddy H J\|van Puijenbroek, Marjo\|Middeldorp, Anneke\|van Eijk, Ronald\|de Meijer, Emile J\|Erasmus, Dianhdra\|Wouters, Kim A D\|van Engeland, Manon\|Oosting, Jan\|Hes, Frederik J\|Tops, Carli M J\|van Wezel, Tom\|Boer, Judith M\|Morreau, Hans
PMID:	20444249

882.
Journal:	Neoplasia. 2010 May;12(5):397-404.
Title:	Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.
Author:	Tsunoda, Toshiyuki\|Takashima, Yasuo\|Fujimoto, Takahiro\|Koyanagi, Midori\|Yoshida, Yasuhiro\|Doi, Keiko\|Tanaka, Yoko\|Kuroki, Masahide\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	20454511

883.
Journal:	BMC Cancer. 2010 May 11;10:189.
Title:	Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas.
Author:	Van Damme, Nancy\|Deron, Philippe\|Van Roy, Nadine\|Demetter, Pieter\|Bols, Alain\|Van Dorpe, Jo\|Baert, Filip\|Van Laethem, Jean-Luc\|Speleman, Franki\|Pauwels, Patrick\|Peeters, Marc
PMID:	20459770

884.
Journal:	Genes Chromosomes Cancer. 2010 Jul;49(7):620-9.
Title:	MDM2 gene amplification in colorectal cancer is associated with disease progression at the primary site, but inversely correlated with distant metastasis.
Author:	Sugano, Nobuhiro\|Suda, Tetsuji\|Godai, Ten-I\|Tsuchida, Kazuhito\|Shiozawa, Manabu\|Sekiguchi, Hironobu\|Yoshihara, Mitsuyo\|Matsukuma, Shoichi\|Sakuma, Yuji\|Tsuchiya, Eiju\|Kameda, Yoichi\|Akaike, Makoto\|Miyagi, Yohei
PMID:	20461754

885.
Journal:	Integr Biol (Camb). 2010 Apr;2(4):202-8.
Title:	Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation.
Author:	Kreeger, Pamela K\|Wang, Yufang\|Haigis, Kevin M\|Lauffenburger, Douglas A
PMID:	20473400

886.
Journal:	Clin Chem Lab Med. 2010 Aug;48(8):1103-6.
Title:	A novel mutant-enriched liquidchip technology for the qualitative detection of somatic mutations in KRAS gene from both serum and tissue samples.
Author:	Wu, Shiyang\|Zhu, Zeyao\|He, Jiaying\|Luo, Xiaodi\|Xu, Jiasen\|Ren-Heidenreich, Lifen
PMID:	20482381

887.
Journal:	BMC Cancer. 2010 May 21;10:227.
Title:	Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features.
Author:	Ang, Pei Woon\|Loh, Marie\|Liem, Natalia\|Lim, Pei Li\|Grieu, Fabienne\|Vaithilingam, Aparna\|Platell, Cameron\|Yong, Wei Peng\|Iacopetta, Barry\|Soong, Richie
PMID:	20492682

888.
Journal:	Nucleic Acids Res. 2010 Oct;38(18):6159-75.
Title:	Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts.
Author:	Thierry, Alain R\|Mouliere, Florent\|Gongora, Celine\|Ollier, Jeremy\|Robert, Bruno\|Ychou, Marc\|Del Rio, Maguy\|Molina, Franck
PMID:	20494973

889.
Journal:	Gan To Kagaku Ryoho. 2010 May;37(5):782-6.
Title:	[Cetuximab for patients with metastatic colorectal cancer-from the result of recent clinical trials].
Author:	Ariyama, Hiroshi\|Kusaba, Hitoshi\|Baba, Eiji
PMID:	20495306

890.
Journal:	Gan To Kagaku Ryoho. 2010 May;37(5):799-804.
Title:	[The anti EGFR antibody indication between the Japanese and overseas guidelines].
Author:	Nozaki, Akira\|Shinozaki, Eiji\|Mizunuma, Nobuyuki
PMID:	20495310

891.
Journal:	Pol J Pathol. 2010;61(1):23-6.
Title:	BRAF mutations in sporadic colorectal carcinoma from polish patients.
Author:	Wojcik, Piotr\|Okon, Krzysztof\|Osuch, Czeslaw\|Klimkowska, Agnieszka\|Tomaszewska, Romana
PMID:	20496269

892.
Journal:	Ann Oncol. 2010 Dec;21(12):2396-402.
Title:	The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients.
Author:	Farina-Sarasqueta, A\|van Lijnschoten, G\|Moerland, E\|Creemers, G-J\|Lemmens, V E P P\|Rutten, H J T\|van den Brule, A J C
PMID:	20501503

893.
Journal:	Mol Cancer. 2010 May 27;9:125.
Title:	Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Author:	Baba, Yoshifumi\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Tanaka, Noriko\|Shima, Kaori\|Hazra, Aditi\|Schernhammer, Eva S\|Hunter, David J\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20507599

894.
Journal:	Cancer J. 2010 May-Jun;16(3):262-72.
Title:	Molecular markers in the treatment of metastatic colorectal cancer.
Author:	Wilson, Peter M\|Labonte, Melissa J\|Lenz, Heinz-Josef
PMID:	20526105

895.
Journal:	J Pathol. 2010 Jul;221(3):239-41.
Title:	Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma.
Author:	Fodde, Riccardo\|Tomlinson, Ian
PMID:	20527017

896.
Journal:	Clin Cancer Res. 2010 Jun 15;16(12):3193-204.
Title:	Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.
Author:	Pitts, Todd M\|Tan, Aik Choon\|Kulikowski, Gillian N\|Tentler, John J\|Brown, Amy M\|Flanigan, Sara A\|Leong, Stephen\|Coldren, Christopher D\|Hirsch, Fred R\|Varella-Garcia, Marileila\|Korch, Christopher\|Eckhardt, S Gail
PMID:	20530704

897.
Journal:	PLoS One. 2010 Jun 4;5(6):e10966.
Title:	Hypoxia activates the K-ras proto-oncogene to stimulate angiogenesis and inhibit apoptosis in colon cancer cells.
Author:	Zeng, Min\|Kikuchi, Hirotoshi\|Pino, Maria S\|Chung, Daniel C
PMID:	20532039

898.
Journal:	Nihon Rinsho. 2010 Jun;68(6):1085-93.
Title:	[Antibody therapy in cancer].
Author:	Komatsu, Hirokazu
PMID:	20535960

899.
Journal:	Cancer Sci. 2010 Sep;101(9):2048-53.
Title:	Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy?
Author:	Paez, David\|Pare, Laia\|Espinosa, Inigo\|Salazar, Juliana\|del Rio, Elisabeth\|Barnadas, Agusti\|Marcuello, Eugenio\|Baiget, Montserrat
PMID:	20550522

900.
Journal:	Oncogene. 2010 Aug 19;29(33):4658-70.
Title:	Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells.
Author:	Wang, Y\|Ngo, V N\|Marani, M\|Yang, Y\|Wright, G\|Staudt, L M\|Downward, J
PMID:	20562906

901.
Journal:	Neoplasia. 2010 Jun;12(6):443-52.
Title:	Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.
Author:	van Houdt, Winan J\|Hoogwater, Frederik J H\|de Bruijn, Menno T\|Emmink, Benjamin L\|Nijkamp, Maarten W\|Raats, Danielle A E\|van der Groep, Petra\|van Diest, Paul\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	20563247

902.
Journal:	BMC Cancer. 2010 Jun 17;10:300.
Title:	SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene.
Author:	Sameer, A Syed\|Chowdri, Nissar A\|Syeed, Nidda\|Banday, Mujeeb Z\|Shah, Zaffar A\|Siddiqi, Mushtaq A
PMID:	20565773

903.
Journal:	Cancer Res. 2010 Jul 15;70(14):5901-11.
Title:	Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Author:	Janakiraman, Manickam\|Vakiani, Efsevia\|Zeng, Zhaoshi\|Pratilas, Christine A\|Taylor, Barry S\|Chitale, Dhananjay\|Halilovic, Ensar\|Wilson, Manda\|Huberman, Kety\|Ricarte Filho, Julio Cezar\|Persaud, Yogindra\|Levine, Douglas A\|Fagin, James A\|Jhanwar, Suresh C\|Mar
PMID:	20570890

904.
Journal:	Clin Lab. 2010;56(5-6):175-86.
Title:	Comparison of two different screening methods for the KRAS mutation in colorectal cancer.
Author:	Er, Tze-Kiong\|Chang, Ya-Sian\|Yeh, Kun-Tu\|Chang, Tien-Jye\|Chang, Jan-Gowth
PMID:	20575464

905.
Journal:	Genetika. 2010 May;46(5):700-8.
Title:	[Mutation analysis of K-ras protooncogene in colorectal adenocarcinomas and polyps in Russian patients].
Author:	Amosenko, F A\|Korchagina, E L\|Matveeva, T I\|Vaganov, Iu E\|Vlasov, S B\|Poltavets, N V\|Veselov, V V\|Gar'kavtseva, R F\|Poliakov, A V
PMID:	20583607

906.
Journal:	Oncologist. 2010;15(7):699-731.
Title:	A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.
Author:	Deschoolmeester, Vanessa\|Baay, Marc\|Specenier, Pol\|Lardon, Filip\|Vermorken, Jan B
PMID:	20584808

907.
Journal:	Drug Discov Today. 2010 Jul;15(13-14):502-16.
Title:	Therapeutic modulation of k-ras signaling in colorectal cancer.
Author:	Krens, Lisanne L\|Baas, Jara M\|Gelderblom, Hans\|Guchelaar, Henk-Jan
PMID:	20594936

908.
Journal:	Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12605-10.
Title:	T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Author:	Lutterbuese, Ralf\|Raum, Tobias\|Kischel, Roman\|Hoffmann, Patrick\|Mangold, Susanne\|Rattel, Benno\|Friedrich, Matthias\|Thomas, Oliver\|Lorenczewski, Grit\|Rau, Doris\|Schaller, Evelyne\|Herrmann, Ines\|Wolf, Andreas\|Urbig, Thomas\|Baeuerle, Patrick A\|Kufer, Peter
PMID:	20616015

909.
Journal:	J Mol Diagn. 2010 Sep;12(5):705-11.
Title:	The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer.
Author:	Mancini, Irene\|Santucci, Claudio\|Sestini, Roberta\|Simi, Lisa\|Pratesi, Nicola\|Cianchi, Fabio\|Valanzano, Rosa\|Pinzani, Pamela\|Orlando, Claudio
PMID:	20616366

910.
Journal:	Carcinogenesis. 2010 Sep;31(9):1604-11.
Title:	Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Lundgreen, Abbie\|Fitzpatrick, Francis A\|Curtin, Karen\|Wolff, Roger K
PMID:	20622004

911.
Journal:	Transl Res. 2010 Aug;156(2):98-105.
Title:	Cycleave polymerase chain reaction method is practically applicable for V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)/V-raf murine sarcoma viral oncogene homolog B1 (BRAF) genotyping in colorectal cancer.
Author:	Yokota, Tomoya\|Shibata, Noriko\|Ura, Takashi\|Takahari, Daisuke\|Shitara, Kohei\|Muro, Kei\|Yatabe, Yasushi
PMID:	20627194

912.
Journal:	Dis Colon Rectum. 2010 Aug;53(8):1182-9.
Title:	Alcohol consumption and rectal tumor mutations and epigenetic changes.
Author:	Slattery, Martha L\|Wolff, Roger K\|Herrick, Jennifer S\|Curtin, Karen\|Caan, Bette J\|Samowitz, Wade
PMID:	20628283

913.
Journal:	Clin Colorectal Cancer. 2010 Jun;9 Suppl 1:S16-27.
Title:	Integrating biomarkers into clinical decision making for colorectal cancer.
Author:	Wilson, Peter M\|Lenz, Heinz-Josef
PMID:	20630847

914.
Journal:	Clin Colorectal Cancer. 2010 Jun;9 Suppl 1:S44-50.
Title:	Treatment paradigms with epidermal growth factor receptor-targeted therapies in colorectal cancer.
Author:	Stein, Stacey\|Cohen, Deirdre J\|Hochster, Howard S
PMID:	20630850

915.
Journal:	Anticancer Drugs. 2010 Sep;21(8):737-48.
Title:	Targeted therapy in advanced colorectal cancer: more data, more questions.
Author:	Ochenduszko, Sebastian L\|Krzemieniecki, Krzysztof
PMID:	20631611

916.
Journal:	Ann Pharm Fr. 2010 Jul;68(4):233-53.
Title:	[Recent developments of pharmacogenomics in the treatment of colorectal cancers].
Author:	Astier, A
PMID:	20637356

917.
Journal:	Fam Cancer. 2010 Dec;9(4):589-94.
Title:	MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.
Author:	Lefevre, Jeremie H\|Colas, Chrystelle\|Coulet, Florence\|Bonilla, Carolina\|Mourra, Najat\|Flejou, Jean-Francois\|Tiret, Emmanuel\|Bodmer, Walter\|Soubrier, Florent\|Parc, Yann
PMID:	20640893

918.
Journal:	Zhonghua Yi Xue Za Zhi. 2010 May 11;90(18):1268-71.
Title:	[Significance of K-ras detection in colorectal cancer].
Author:	Xu, Xiang-ming\|Zhang, Guo-liang\|Li, Min-wei\|Wang, Dan-yang\|Lin, Jian-jiang
PMID:	20646601

919.
Journal:	Jpn J Clin Oncol. 2010 Sep;40(9):855-62.
Title:	Progress in cancer chemotherapy with special stress on molecular-targeted therapy.
Author:	Saijo, Nagahiro
PMID:	20651047

920.
Journal:	Anticancer Res. 2010 Jun;30(6):1969-75.
Title:	KRAS and BRAF mutation analysis from liquid-based cytology brushings of colorectal carcinoma in comparison with formalin-fixed, paraffin-embedded tissue.
Author:	Spathis, Aris\|Georgoulakis, John\|Foukas, Periklis\|Kefala, Maria\|Leventakos, Konstantinos\|Machairas, Anastasios\|Panayiotides, Ioannis\|Karakitsos, Petros
PMID:	20651341

921.
Journal:	Anat Rec (Hoboken). 2010 Sep;293(9):1506-11.
Title:	Gene mutations in epidermal growth factor receptor signaling network and their association with survival in Chinese patients with metastatic colorectal cancers.
Author:	Liao, Wangjun\|Liao, Yulin\|Zhou, Jeff X\|Xie, Jianming\|Chen, Jinzhang\|Huang, Weizhen\|Luo, Rongcheng
PMID:	20652941

922.
Journal:	Cancer. 2010 Nov 1;116(21):4954-64.
Title:	The prognostic value of c-Kit, K-ras codon 12, and p53 codon 72 mutations in Egyptian patients with stage II colorectal cancer.
Author:	El-Serafi, Mostafa M\|Bahnassy, Abeer A\|Ali, Nasr M\|Eid, Salem M\|Kamel, Mahmoud M\|Abdel-Hamid, Nayera A\|Zekri, Abdel-Rahman N
PMID:	20652953

923.
Journal:	Clin Gastroenterol Hepatol. 2010 Nov;8(11):966-71.
Title:	Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer.
Author:	Goel, Ajay\|Nagasaka, Takeshi\|Spiegel, Jennifer\|Meyer, Richard\|Lichliter, Warren E\|Boland, C Richard
PMID:	20655395

924.
Journal:	Mol Cancer. 2010 Jul 30;9:203.
Title:	Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.
Author:	Bavi, Prashant\|Prabhakaran, Sarita E\|Abubaker, Jehad\|Qadri, Zeeshan\|George, Thara\|Al-Sanea, Nasser\|Abduljabbar, Alaa\|Ashari, Luai H\|Alhomoud, Samar\|Al-Dayel, Fouad\|Hussain, Azhar R\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	20673328

925.
Journal:	Curr Oncol. 2010 Jul;17 Suppl 1:S31-40.
Title:	KRAS mutation testing in the treatment of metastatic colorectal cancer with anti-EGFR therapies.
Author:	Soulieres, D\|Greer, W\|Magliocco, Anthony M\|Huntsman, D\|Young, S\|Tsao, M-S\|Kamel-Reid, S
PMID:	20680106

926.
Journal:	Gastroenterology. 2010 Dec;139(6):1855-64.
Title:	Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Huttenhower, Curtis\|Tanaka, Noriko\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20682317

927.
Journal:	Cancer Genet Cytogenet. 2010 Sep;201(2):128-32.
Title:	Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
Author:	Pehlivan, Sacide\|Artac, Mehmet\|Sever, Tugce\|Bozcuk, Hakan\|Kilincarslan, Can\|Pehlivan, Mustafa
PMID:	20682398

928.
Journal:	Intern Med. 2010;49(15):1637-40. Epub 2010 Aug 2.
Title:	Epigenetic inactivation of tumor suppressor SFRP2 and point mutation in KRAS proto-oncogene in fistula-associated mucinous type anal adenocarcinoma: report of two cases.
Author:	Sen, Metin\|Ozdemir, Ozturk\|Turan, Mustafa\|Arici, Sema\|Yildiz, Fazilet\|Koksal, Binnur\|Goze, Fahrettin
PMID:	20686305

929.
Journal:	BMC Cancer. 2010 Aug 9;10:413.
Title:	Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
Author:	Scheel, Silvio K\|Porzner, Marc\|Pfeiffer, Sabine\|Ormanns, Steffen\|Kirchner, Thomas\|Jung, Andreas
PMID:	20696052

930.
Journal:	J Natl Compr Canc Netw. 2010 Jul;8 Suppl 3:S22-5.
Title:	Modification and implementation of NCCN guidelines on colon cancer in the Middle East and North Africa region.
Author:	Icli, Fikri\|Akbulut, Hakan\|Bazarbashi, Shouki\|Kuzu, Mehmet Ayhan\|Mallath, Mohandas K\|Rasul, Kakil Ibrahim\|Strong, Scott\|Syed, Aamir Ali\|Zorlu, Faruk\|Engstrom, Paul F
PMID:	20697127

931.
Journal:	Biomark Med. 2010 Aug;4(4):535-41.
Title:	Use of K-Ras as a predictive biomarker for selecting anti-EGF receptor/pathway treatment.
Author:	Jiang, Yixing\|Mackley, Heath\|Cheng, Hua\|Ajani, Jaffer A
PMID:	20701442

932.
Journal:	Ann Surg Oncol. 2010 Dec;17(12):3370-8.
Title:	Improved testing for microsatellite instability in colorectal cancer using a simplified 3-marker assay.
Author:	Esemuede, Iyare\|Forslund, Ann\|Khan, Sajid A\|Qin, Li-Xuan\|Gimbel, Mark I\|Nash, Garrett M\|Zeng, Zhaoshi\|Rosenberg, Shoshana\|Shia, Jinru\|Barany, Francis\|Paty, Philip B
PMID:	20703819

933.
Journal:	Cancer Cell. 2010 Aug 9;18(2):135-46.
Title:	Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis.
Author:	Bennecke, Moritz\|Kriegl, Lydia\|Bajbouj, Monther\|Retzlaff, Kristin\|Robine, Sylvie\|Jung, Andreas\|Arkan, Melek C\|Kirchner, Thomas\|Greten, Florian R
PMID:	20708155

934.
Journal:	Pharmacogenomics. 2010 Aug;11(8):1169-79.
Title:	Detection of KRAS mutations in colorectal carcinoma patients with an integrated PCR/sequencing and real-time PCR approach.
Author:	Carotenuto, Pietro\|Roma, Cristin\|Rachiglio, Anna Maria\|Tatangelo, Fabiana\|Pinto, Carmine\|Ciardiello, Fortunato\|Nappi, Oscar\|Iaffaioli, R Vincenzo\|Botti, Gerardo\|Normanno, Nicola
PMID:	20712532

935.
Journal:	J Clin Oncol. 2010 Sep 20;28(27):4240-6.
Title:	Randomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer.
Author:	Reidy, Diane Lauren\|Vakiani, Efsevia\|Fakih, Marwan G\|Saif, Muhammad Wasif\|Hecht, Joel Randolph\|Goodman-Davis, Noah\|Hollywood, Ellen\|Shia, Jinru\|Schwartz, Jonathan\|Chandrawansa, Kumari\|Dontabhaktuni, Aruna\|Youssoufian, Hagop\|Solit, David B\|Saltz, Leonard B
PMID:	20713879

936.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):813-23.
Title:	KRAS mutation testing of colorectal cancer for anti-EGFR therapy: dogmas versus evidence.
Author:	Timar, Jozsef\|Hegedus, Balazs\|Raso, Erzsebet
PMID:	20718705

937.
Journal:	Curr Cancer Drug Targets. 2010 Dec;10(8):799-812.
Title:	Predictive molecular markers of response to epidermal growth factor receptor(EGFR) family-targeted therapies.
Author:	Barton, Sarah\|Starling, Naureen\|Swanton, Charles
PMID:	20718710

938.
Journal:	Genes Chromosomes Cancer. 2010 Nov;49(11):1024-34.
Title:	Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas.
Author:	Gaedcke, Jochen\|Grade, Marian\|Jung, Klaus\|Camps, Jordi\|Jo, Peter\|Emons, Georg\|Gehoff, Anastasia\|Sax, Ulrich\|Schirmer, Markus\|Becker, Heinz\|Beissbarth, Tim\|Ried, Thomas\|Ghadimi, B Michael
PMID:	20725992

939.
Journal:	Mol Cell Probes. 2010 Dec;24(6):376-80.
Title:	High sensitive mutation analysis on KRAS gene using LNA/DNA chimeras as PCR amplification blockers of wild-type alleles.
Author:	Huang, Qing\|Wang, Gui-Yu\|Huang, Jun-Fu\|Zhang, Bo\|Fu, Wei-Ling
PMID:	20732413

940.
Journal:	Clin Adv Hematol Oncol. 2010 Jun;8(6):437-44.
Title:	BRAF testing in advanced colorectal cancer: is it ready for prime time?
Author:	Phillips, Brooke\|Kalady, Matthew\|Kim, Richard
PMID:	20733556

941.
Journal:	Electrophoresis. 2010 Sep;31(18):3137-43.
Title:	A miniaturized spatial temperature gradient capillary electrophoresis system with radiative heating and automated sample introduction for DNA mutation detection.
Author:	Xu, Zhang-Run\|Li, Qi\|Fan, Xiao-Feng\|Zhang, Hui-Dan\|Fang, Jin
PMID:	20734373

942.
Journal:	Diagn Mol Pathol. 2010 Sep;19(3):157-63.
Title:	NRAS mutations are rare in colorectal cancer.
Author:	Irahara, Natsumi\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Yan, Liying\|Dias-Santagata, Dora\|Iafrate, Anthony John\|Fuchs, Charles S\|Haigis, Kevin M\|Ogino, Shuji
PMID:	20736745

943.
Journal:	Case Rep Oncol. 2010 May 7;3(2):154-159.
Title:	Long-Lasting Tumor Response in Patients with Panitumumab Monotherapy for Chemorefractory Metastatic Colorectal Carcinoma - A Report of Two Cases.
Author:	Ramadori, G\|Cameron, S\|Tschechne, B
PMID:	20740189

944.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1025-33.
Title:	Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer.
Author:	Baba, Y\|Nosho, K\|Shima, K\|Meyerhardt, J A\|Chan, A T\|Engelman, J A\|Cantley, L C\|Loda, M\|Giovannucci, E\|Fuchs, C S\|Ogino, S
PMID:	20808308

945.
Journal:	Cancer Res. 2010 Sep 15;70(18):7253-63.
Title:	Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2.
Author:	Mologni, Luca\|Dekhil, Hafedh\|Ceccon, Monica\|Purgante, Stefania\|Lan, Cathy\|Cleris, Loredana\|Magistroni, Vera\|Formelli, Franca\|Gambacorti-Passerini, Carlo B
PMID:	20823162

946.
Journal:	Pathologe. 2010 Oct;31 Suppl 2:280-4.
Title:	[mRNA quantification. The next challenge in routine diagnostics].
Author:	Jung, A\|Jaitner, S\|Schaffauer, A J\|Kirchner, T
PMID:	20824431

947.
Journal:	Gastroenterol Clin Biol. 2010 Dec;34(12):662-81.
Title:	Circulating free tumor DNA and colorectal cancer.
Author:	Lecomte, T\|Ceze, N\|Dorval, E\|Laurent-Puig, P
PMID:	20832215

948.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2777-85.
Title:	Cathepsin B expression and survival in colon cancer: implications for molecular detection of neoplasia.
Author:	Chan, Andrew T\|Baba, Yoshifumi\|Shima, Kaori\|Nosho, Katsuhiko\|Chung, Daniel C\|Hung, Kenneth E\|Mahmood, Umar\|Madden, Karen\|Poss, Kirtland\|Ranieri, Audrey\|Shue, Daniel\|Kucherlapati, Raju\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20833970

949.
Journal:	Expert Rev Anticancer Ther. 2010 Sep;10(9):1371-3.
Title:	American Society of Clinical Oncology 2010 colorectal update.
Author:	Murphy, Janet E\|Ryan, David P
PMID:	20836671

950.
Journal:	Br J Cancer. 2010 Sep 28;103(7):1019-24.
Title:	Prognostic role of EGFR gene copy number and KRAS mutation in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy.
Author:	Bengala, C\|Bettelli, S\|Bertolini, F\|Sartori, G\|Fontana, A\|Malavasi, N\|Depenni, R\|Zironi, S\|Del Giovane, C\|Luppi, G\|Conte, P F
PMID:	20842128

951.
Journal:	Hum Mutat. 2010 Dec;31(12):1366-73.
Title:	Increased sensitivity of KRAS mutation detection by high-resolution melting analysis of COLD-PCR products.
Author:	Kristensen, Lasse S\|Daugaard, Iben L\|Christensen, Mariann\|Hamilton-Dutoit, Stephen\|Hager, Henrik\|Hansen, Lise Lotte
PMID:	20848649

952.
Journal:	J Clin Oncol. 2010 Dec 20;28(36):e756-8.
Title:	Patient with colorectal cancer with heterogeneous KRAS molecular status responding to cetuximab-based chemotherapy.
Author:	Mancuso, Andrea\|Sollami, Rossella\|Recine, Federica\|Cerbone, Linda\|Macciomei, Maria Cristina\|Leone, Alvaro
PMID:	20855834

953.
Journal:	Adv Clin Chem. 2010;51:71-119.
Title:	EGFR and KRAS in colorectal cancer.
Author:	Markman, Ben\|Javier Ramos, Francisco\|Capdevila, Jaume\|Tabernero, Josep
PMID:	20857619

954.
Journal:	Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17604-9.
Title:	A mathematical framework to determine the temporal sequence of somatic genetic events in cancer.
Author:	Attolini, Camille Stephan-Otto\|Cheng, Yu-Kang\|Beroukhim, Rameen\|Getz, Gad\|Abdel-Wahab, Omar\|Levine, Ross L\|Mellinghoff, Ingo K\|Michor, Franziska
PMID:	20864632

955.
Journal:	PLoS Curr. 2010 Sep 2;2. pii: RRN1175.
Title:	KRAS mutational analysis for colorectal cancer. Application: pharmacogenomic.
Author:	Wang, Grace\|Kelley, Robin K\|Gappnet
PMID:	20877448

956.
Journal:	J Clin Oncol. 2010 Nov 1;28(31):4769-77.
Title:	Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
Author:	Roberts, Patrick J\|Stinchcombe, Thomas E\|Der, Channing J\|Socinski, Mark A
PMID:	20921461

957.
Journal:	Clin Cancer Res. 2010 Nov 15;16(22):5402-13.
Title:	MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer.
Author:	Giraldez, Maria Dolores\|Balaguer, Francesc\|Bujanda, Luis\|Cuatrecasas, Miriam\|Munoz, Jenifer\|Alonso-Espinaco, Virginia\|Larzabal, Mikel\|Petit, Anna\|Gonzalo, Victoria\|Ocana, Teresa\|Moreira, Leticia\|Enriquez-Navascues, Jose Maria\|Boland, C Richard\|Goel, Ajay\|
PMID:	20924129

958.
Journal:	J Pathol. 2010 Dec;222(4):350-66.
Title:	Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.
Author:	Nosho, Katsuhiko\|Baba, Yoshifumi\|Tanaka, Noriko\|Shima, Kaori\|Hayashi, Marika\|Meyerhardt, Jeffrey A\|Giovannucci, Edward\|Dranoff, Glenn\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20927778

959.
Journal:	Expert Rev Gastroenterol Hepatol. 2010 Oct;4(5):525-9.
Title:	Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond.
Author:	Katsios, Christos\|Ziogas, Dimosthenis E\|Roukos, Dimitrios H
PMID:	20932136

960.
Journal:	Clin Cancer Res. 2010 Nov 15;16(22):5591-602.
Title:	Germline polymorphisms in genes involved in the IGF1 pathway predict efficacy of cetuximab in wild-type KRAS mCRC patients.
Author:	Winder, Thomas\|Zhang, Wu\|Yang, Dongyun\|Ning, Yan\|Bohanes, Pierre\|Gerger, Armin\|Wilson, Peter M\|Pohl, Alexandra\|Mauro, David J\|Langer, Christiane\|Rowinsky, Eric K\|Lenz, Heinz-Josef
PMID:	20935157

961.
Journal:	World J Gastroenterol. 2010 Oct 14;16(38):4858-64.
Title:	Comparative analysis of dideoxy sequencing, the KRAS StripAssay and pyrosequencing for detection of KRAS mutation.
Author:	Gao, Jing\|Li, Yan-Yan\|Sun, Ping-Nai\|Shen, Lin
PMID:	20939116

962.
Journal:	Mol Cancer. 2010 Oct 13;9:271.
Title:	The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis.
Author:	Bergeron, Sebastien\|Lemieux, Etienne\|Durand, Veronique\|Cagnol, Sebastien\|Carrier, Julie C\|Lussier, Jacques G\|Boucher, Marie-Josee\|Rivard, Nathalie
PMID:	20942929

963.
Journal:	Ann Oncol. 2010 Oct;21 Suppl 7:vii123-9.
Title:	What can the molecular pathologist offer for optimal decision making?
Author:	Richman, S D\|Hutchins, G G A\|Seymour, M T\|Quirke, P
PMID:	20943604

964.
Journal:	Gastroenterol Clin North Am. 2010 Sep;39(3):601-13.
Title:	Targeted therapeutic agents for colorectal cancer.
Author:	Chee, Cheng E\|Sinicrope, Frank A
PMID:	20951919

965.
Journal:	Br J Cancer. 2010 Nov 9;103(10):1627-36.
Title:	KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis.
Author:	Deschoolmeester, V\|Boeckx, C\|Baay, M\|Weyler, J\|Wuyts, W\|Van Marck, E\|Peeters, M\|Lardon, F\|Vermorken, J B
PMID:	20959826

966.
Journal:	Clin Transl Oncol. 2010 Nov;12(11):729-34.
Title:	SEOM clinical guidelines for the treatment of advanced colorectal cancer.
Author:	Garcia-Carbonero, Rocio\|Gomez Espana, M Auxiliadora\|Casado Saenz, Enrique\|Alonso Orduna, Vicente\|Cervantes Ruiperez, Andres\|Gallego Plazas, Javier\|Garcia Alfonso, Pilar\|Juez Martel, Ignacio\|Gonzalez Flores, Encarnacion\|Lomas Garrido, Maria\|Isla Casado, Do
PMID:	20974564

967.
Journal:	JAMA. 2010 Oct 27;304(16):1812-20.
Title:	Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.
Author:	De Roock, Wendy\|Jonker, Derek J\|Di Nicolantonio, Federica\|Sartore-Bianchi, Andrea\|Tu, Dongsheng\|Siena, Salvatore\|Lamba, Simona\|Arena, Sabrina\|Frattini, Milo\|Piessevaux, Hubert\|Van Cutsem, Eric\|O'Callaghan, Chris J\|Khambata-Ford, Shirin\|Zalcberg, John R\|Si
PMID:	20978259

968.
Journal:	BMC Cancer. 2010 Oct 27;10:587.
Title:	Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
Author:	Pinheiro, Manuela\|Ahlquist, Terje\|Danielsen, Stine A\|Lind, Guro E\|Veiga, Isabel\|Pinto, Carla\|Costa, Vera\|Afonso, Luis\|Sousa, Olga\|Fragoso, Maria\|Santos, Lucio\|Henrique, Rui\|Lopes, Paula\|Lopes, Carlos\|Lothe, Ragnhild A\|Teixeira, Manuel R
PMID:	20979647

969.
Journal:	Anticancer Res. 2010 Oct;30(10):4209-17.
Title:	Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study).
Author:	Zhang, Wu\|Azuma, Mizutomo\|Lurje, Georg\|Gordon, Michael A\|Yang, Dongyun\|Pohl, Alexandra\|Ning, Yan\|Bohanes, Pierre\|Gerger, Armin\|Winder, Thomas\|Hollywood, Ellen\|Danenberg, Kathleen D\|Saltz, Leonard\|Lenz, Heinz-Josef
PMID:	21036743

970.
Journal:	Anticancer Res. 2010 Oct;30(10):4229-35.
Title:	Concordant analysis of KRAS status in primary colon carcinoma and matched metastasis.
Author:	Mariani, Pascale\|Lae, Marick\|Degeorges, Armelle\|Cacheux, Wulfran\|Lappartient, Emmanuelle\|Margogne, Audrey\|Pierga, Jean-Yves\|Girre, Veronique\|Mignot, Laurent\|Falcou, Marie Christine\|Salmon, Remy-Jacques\|Delattre, Olivier\|De Cremoux, Patricia
PMID:	21036746

971.
Journal:	Am J Pathol. 2010 Dec;177(6):2731-40.
Title:	Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author:	Tanaka, Noriko\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Shima, Kaori\|Quackenbush, John\|Haigis, Kevin M\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21037082

972.
Journal:	Diagn Mol Pathol. 2010 Dec;19(4):201-8.
Title:	High sensitivity of reverse-hybridization methodology in the detection of KRAS mutations from formalin-fixed paraffin-embedded colorectal cancer samples.
Author:	De Miglio, Maria Rosaria\|Mura, Antonica\|Uras, Maria Gabriela\|Manca, Alessandra\|Contini, Marcella\|Murgia, Luciano\|Zinellu, Angelo\|Sotgia, Salvatore\|Carru, Ciriaco\|Massarelli, Giovannino\|Cossu-Rocca, Paolo
PMID:	21052001

973.
Journal:	J Cell Biochem. 2010 Dec 1;111(5):1082-6.
Title:	Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer.
Author:	Chen, Jiezhong\|Huang, Xu-Feng\|Katsifis, Andrew
PMID:	21053280

974.
Journal:	Duodecim. 2010;126(17):2002-11.
Title:	[Colorectal serrated lesions: current insight on their role in colorectal carcinogenesis].
Author:	Makinen, Markus
PMID:	21053517

975.
Journal:	Zhonghua Wai Ke Za Zhi. 2010 Aug 15;48(16):1247-51.
Title:	[K-ras gene mutation in colorectal cancer and its clinicopathologic significance].
Author:	Yuan, Ying\|Hu, Han-guang\|Ye, Xiao-xian\|Shen, Hong\|Zheng, Shu
PMID:	21055216

976.
Journal:	Mol Cancer. 2010 Nov 13;9:293.
Title:	Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1alpha and HIF-2alpha target genes.
Author:	Chun, Sang Y\|Johnson, Craig\|Washburn, Joseph G\|Cruz-Correa, Marcia R\|Dang, Duyen T\|Dang, Long H
PMID:	21073737

977.
Journal:	Gan To Kagaku Ryoho. 2010 Nov;37(11):2189-91.
Title:	[Two cases of colorectal cancer patients with poor performance status who had unresectable liver metastasis effectively treated by cetuximab].
Author:	Osawa, Gakuji\|Yoshimatsu, Kazuhiko\|Yokomizo, Hajime\|Matsumoto, Atsuo\|Yano, Yuki\|Itagaki, Hiroko\|Otani, Taisuke\|Fujimoto, Takashi\|Umehara, Arihiro\|Ogawa, Kenji
PMID:	21084825

978.
Journal:	PLoS One. 2010 Nov 12;5(11):e13978.
Title:	DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
Author:	Berg, Marianne\|Danielsen, Stine A\|Ahlquist, Terje\|Merok, Marianne A\|Agesen, Trude H\|Vatn, Morten H\|Mala, Tom\|Sjo, Ole H\|Bakka, Arne\|Moberg, Ingvild\|Fetveit, Torunn\|Mathisen, Oystein\|Husby, Anders\|Sandvik, Oddvar\|Nesbakken, Arild\|Thiis-Evensen, Espen\|Lothe
PMID:	21103049

979.
Journal:	Swiss Med Wkly. 2010 Nov 19;140:w13112.
Title:	Kras in metastatic colorectal cancer.
Author:	Wicki, Andreas\|Herrmann, Richard\|Christofori, Gerhard
PMID:	21104470

980.
Journal:	BMC Clin Pathol. 2010 Nov 26;10:6.
Title:	COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma.
Author:	Pritchard, Colin C\|Akagi, Laura\|Reddy, Poluru L\|Joseph, Loren\|Tait, Jonathan F
PMID:	21110880

981.
Journal:	BMC Cancer. 2010 Dec 1;10:660.
Title:	KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice.
Author:	Sundstrom, Magnus\|Edlund, Karolina\|Lindell, Monica\|Glimelius, Bengt\|Birgisson, Helgi\|Micke, Patrick\|Botling, Johan
PMID:	21122130

982.
Journal:	Tohoku J Exp Med. 2010 Dec;222(4):243-50.
Title:	Increased expression of annexin A1 is correlated with K-ras mutation in colorectal cancer.
Author:	Su, Ning\|Xu, Xin-Yun\|Chen, Han\|Gao, Wen-Chao\|Ruan, Can-Ping\|Wang, Qiang\|Sun, Yan-Ping
PMID:	21127395

983.
Journal:	Cancer Treat Rev. 2010 Nov;36 Suppl 3:S56-61.
Title:	Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy?
Author:	Rizzo, Sergio\|Bronte, Giuseppe\|Fanale, Daniele\|Corsini, Lidia\|Silvestris, Nicola\|Santini, Daniele\|Gulotta, Gaspare\|Bazan, Viviana\|Gebbia, Nicola\|Fulfaro, Fabio\|Russo, Antonio
PMID:	21129611

984.
Journal:	Br J Cancer. 2010 Dec 7;103(12):1765-72.
Title:	Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer.
Author:	Di Fiore, F\|Sesboue, R\|Michel, P\|Sabourin, J C\|Frebourg, T
PMID:	21139621

985.
Journal:	Curr Oncol. 2010 Nov;17(6):39-45.
Title:	Consensus recommendations for the use of anti-egfr therapies in metastatic colorectal cancer.
Author:	Cripps, C\|Gill, S\|Ahmed, S\|Colwell, B\|Dowden, S\|Kennecke, H\|Maroun, J\|Samson, B\|Thirlwell, M\|Wong, R
PMID:	21151408

986.
Journal:	World J Gastroenterol. 2010 Dec 14;16(46):5881-8.
Title:	Impact of KRAS mutation and PTEN expression on cetuximab-treated colorectal cancer.
Author:	Li, Fang-Hua\|Shen, Lin\|Li, Zhuang-Hua\|Luo, Hui-Yan\|Qiu, Miao-Zhen\|Zhang, Hui-Zhong\|Li, Yu-Hong\|Xu, Rui-Hua
PMID:	21155011

987.
Journal:	World J Gastrointest Surg. 2010 Oct 27;2(10):314-8.
Title:	Population-based epidemiology, risk factors and screening of intraductal papillary mucinous neoplasm patients.
Author:	Khan, Saboor\|Sclabas, Guido\|Reid-Lombardo, Kaye M
PMID:	21160836

988.
Journal:	Int J Biol Markers. 2010 Oct-Dec;25(4):179-84.
Title:	Mutation analysis of BRAF exon 15 and KRAS codons 12 and 13 in Moroccan patients with colorectal cancer.
Author:	Bennani, Bahia\|Gilles, Sophie\|Fina, Frederic\|Nanni, Isabelle\|Ibrahimi, Sidi Adil\|Riffi, Afaf Amarti\|Nejjari, Chakib\|Benajeh, Dafr-Allah\|El Abkari, Mohammed\|Martin, Pierre-Marie\|Ouafik, L'Houcine
PMID:	21161938

989.
Journal:	Magy Onkol. 2010 Dec;54(4):383-94.
Title:	Predictive and prognostic factors in the complex treatment of patients with colorectal cancer.
Author:	Laszlo, Landherr
PMID:	21163770

990.
Journal:	Prescrire Int. 2010 Oct;19(109):219-24.
Title:	Chemotherapy of metastatic colorectal cancer.
Author:
PMID:	21180382

991.
Journal:	Anticancer Res. 2010 Dec;30(12):5251-6.
Title:	KRAS genotyping as biomarker in colorectal cancer: a comparison of three commercial kits on histologic material.
Author:	Cavallini, Aldo\|Valentini, Anna Maria\|Lippolis, Catia\|Campanella, Daniela\|Guerra, Vito\|Caruso, Maria Lucia
PMID:	21187522

992.
Journal:	Gastroenterol Res Pract. 2010;2010:789363.
Title:	Analysis of KRAS Mutations of Exon 2 Codons 12 and 13 by SNaPshot Analysis in Comparison to Common DNA Sequencing.
Author:	Zinsky, Rica\|Bolukbas, Servet\|Bartsch, Holger\|Schirren, Joachim\|Fisseler-Eckhoff, Annette
PMID:	21197450

993.
Journal:	Rev Prat. 2010 Oct 20;60(8):1094-9.
Title:	[Targeted therapies in colorectal cancer].
Author:	Sablin, Marie-Paule\|Dreyer, Chantal\|Colichi, Camelia\|Bouattour, Mohamed\|Faivre, Sandrine
PMID:	21197741

994.
Journal:	Clin Colorectal Cancer. 2010 Dec;9(5):269-73.
Title:	Targeted therapies as adjuvant treatment for early-stage colorectal cancer: first impressions and clinical questions.
Author:	Chibaudel, Benoist\|Tournigand, Christophe\|Andre, Thierry\|Larsen, Annette K\|de Gramont, Aimery
PMID:	21208840

995.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2010 Nov;39(11):757-61.
Title:	[Screening for K-ras mutations in colorectal and lung cancers by using a novel real-time PCR with ADx-K-ras kit and Sanger DNA sequencing].
Author:	Zhang, Hai-Ping\|Fu, Li\|Chen, Pei-Qiong\|Ye, Yun-Bin\|Ji, Tian-Hai\|Zheng, Li-Mou
PMID:	21215167

996.
Journal:	Bull Cancer. 2010 Dec;97(12):1441-52.
Title:	[Clinical significance of BRAF mutations in colorectal cancer].
Author:	Lievre, A\|Rouleau, E\|Buecher, B\|Mitry, E
PMID:	21220223

997.
Journal:	Mol Diagn Ther. 2010 Dec 1;14(6):375-84.
Title:	Cost-effectiveness analysis of KRAS testing and cetuximab as last-line therapy for colorectal cancer.
Author:	Shiroiwa, Takeru\|Motoo, Yoshiharu\|Tsutani, Kiichiro
PMID:	21275455

998.
Journal:	Acta Gastroenterol Belg. 2010 Oct-Dec;73(4):497-503.
Title:	Accurate KRAS mutation testing for EGFR-targeted therapy in colorectal cancer: emphasis on the key role and responsibility of pathologists.
Author:	Hoorens, A\|Jouret-Mourin, A\|Sempoux, C\|Demetter, P\|De Hertogh, G\|Teugels, E
PMID:	21299161

999.
Journal:	Oncology. 2010;79(5-6):415-22.
Title:	Cetuximab plus FOLFOX-4 in untreated patients with advanced colorectal cancer: a Gruppo Oncologico dell'Italia Meridionale Multicenter phase II study.
Author:	Colucci, Giuseppe\|Giuliani, Francesco\|Garufi, Carlo\|Mattioli, Rodolfo\|Manzione, Luigi\|Russo, Antonio\|Lopez, Massimo\|Parrella, Paola\|Tommasi, Stefania\|Copetti, Massimiliano\|Daniele, Bruno\|Pisconti, Salvatore\|Tuveri, Guido\|Silvestris, Nicola\|Maiello, Evaris
PMID:	21474966

1000.
Journal:	Folia Histochem Cytobiol. 2010 Dec;48(4):597-602.
Title:	Molecular differences in the KRAS gene mutation between a primary tumor and related metastatic sites - case report and a literature review.
Author:	Kosakowska, Ewa Anna\|Stec, Rafal\|Charkiewicz, Radoslaw\|Skoczek, Marta\|Chyczewski, Lech
PMID:	21478103

1001.
Journal:	Cancer Biomark. 2010-2011;8(2):89-94.
Title:	LNA-based PCR clamping enrichment assay for the identification of KRAS mutations.
Author:	Efrati, Edna\|Elkin, Hela\|Peerless, Yehudit\|Sabo, Edmond\|Ben-Izhak, Ofer\|Hershkovitz, Dov
PMID:	21896996

1002.
Journal:	Cancer Biomark. 2010-2011;8(6):331-40.
Title:	KRAS mutation detection in Tunisian sporadic coloractal cancer patients with direct sequencing, high resolution melting and denaturating high performance liquid chromatography.
Author:	Karim, Bougatef\|Florence, Coulet\|Kamel, Rouissi\|Nadia, Kourda\|Ines, Omrane\|Raja, Marrakchi\|Sarra, Ben Jileni\|Florent, Soubrier\|Amel, Ben Ammar-Elgaaied
PMID:	22072121

1003.
Journal:	J Gastrointest Oncol. 2010 Dec;1(2):90-6.
Title:	KRAS status and clinical outcome in metastatic colorectal cancer patients treated with first-line FOLFOX chemotherapy.
Author:	Sharma, Neelesh\|Saifo, Maher\|Tamaskar, Ila R\|Bhuvaneswari, Ramkumar\|Mashtare, Terry\|Fakih, Marwan
PMID:	22811812

1004.
Journal:	Ont Health Technol Assess Ser. 2010;10(25):1-49. Epub 2010 Dec 1.
Title:	KRAS Testing for Anti-EGFR Therapy in Advanced Colorectal Cancer: An Evidence-Based and Economic Analysis.
Author:
PMID:	23074403

1005.
Journal:
Title:
Author:	Terasawa, Teruhiko\|Dahabreh, Issa\|Castaldi, Peter J\|Trikalinos, Thomas A
PMID:	26065050

1006.
Journal:	Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title:	Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author:	Shima, Kaori\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Cantor, Mami\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20473920

1007.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1315-20.
Title:	KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer.
Author:	Herreros-Villanueva, Marta\|Rodrigo, Maximiliano\|Claver, Manuel\|Muniz, Pilar\|Lastra, Enrique\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20563851

1008.
Journal:	Mol Biol Rep. 2011 Feb;38(2):1347-51.
Title:	PIK3CA mutations in KRAS and BRAF wild type colorectal cancer patients. A study of Spanish population.
Author:	Herreros-Villanueva, Marta\|Gomez-Manero, Noemi\|Muniz, Pilar\|Garcia-Giron, Carlos\|Coma del Corral, Maria Jesus
PMID:	20571907

1009.
Journal:	Diagn Cytopathol. 2011 Apr;39(4):274-7.
Title:	KRAS testing on colo-rectal carcinoma cytological imprints.
Author:	Malapelle, Umberto\|Bellevicine, Claudio\|Russo, Anna\|Salatiello, Maria\|Palombini, Lucio\|Troncone, Giancarlo
PMID:	20607679

1010.
Journal:	Int J Cancer. 2011 May 1;128(9):2075-84.
Title:	Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation.
Author:	Tie, Jeanne\|Gibbs, Peter\|Lipton, Lara\|Christie, Michael\|Jorissen, Robert N\|Burgess, Antony W\|Croxford, Matthew\|Jones, Ian\|Langland, Rachel\|Kosmider, Suzanne\|McKay, Daniel\|Bollag, Gideon\|Nolop, Keith\|Sieber, Oliver M\|Desai, Jayesh
PMID:	20635392

1011.
Journal:	Med Oncol. 2011 Dec;28(4):1048-53.
Title:	Distribution of some activating KRAS and BRAF mutations in Slovene patients with colorectal cancer.
Author:	Licar, Alenka\|Cerkovnik, Petra\|Novakovic, Srdjan
PMID:	20645028

1012.
Journal:	Jpn J Clin Oncol. 2011 Jan;41(1):52-6.
Title:	Feasibility and robustness of amplification refractory mutation system (ARMS)-based KRAS testing using clinically available formalin-fixed, paraffin-embedded samples of colorectal cancers.
Author:	Ogasawara, Naomi\|Bando, Hideaki\|Kawamoto, Yasuyuki\|Yoshino, Takayuki\|Tsuchihara, Katsuya\|Ohtsu, Atsushi\|Esumi, Hiroyasu
PMID:	20696815

1013.
Journal:	Cancer Treat Rev. 2011 May;37(3):221-33.
Title:	All about KRAS for clinical oncology practice: gene profile, clinical implications and laboratory recommendations for somatic mutational testing in colorectal cancer.
Author:	Linardou, Helena\|Briasoulis, Evangelos\|Dahabreh, Issa J\|Mountzios, Giannis\|Papadimitriou, Christos\|Papadopoulos, Savvas\|Bafaloukos, Dimitrios\|Kosmidis, Paris\|Murray, Samuel
PMID:	20817364

1014.
Journal:	Int J Cancer. 2011 Jun 15;128(12):2938-46.
Title:	EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer.
Author:	Ho-Pun-Cheung, Alexandre\|Assenat, Eric\|Bascoul-Mollevi, Caroline\|Bibeau, Frederic\|Boissiere-Michot, Florence\|Cellier, Dominic\|Azria, David\|Rouanet, Philippe\|Senesse, Pierre\|Ychou, Marc\|Lopez-Crapez, Evelyne
PMID:	20824716

1015.
Journal:	Cancer Immunol Immunother. 2011 Jan;60(1):61-73.
Title:	Lenalidomide enhances antibody-dependent cellular cytotoxicity of solid tumor cells in vitro: influence of host immune and tumor markers.
Author:	Wu, Lei\|Parton, Anastasia\|Lu, Ling\|Adams, Mary\|Schafer, Peter\|Bartlett, J Blake
PMID:	20848094

1016.
Journal:	Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):677-83.
Title:	Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase II study.
Author:	Kim, Sun Young\|Hong, Yong Sang\|Kim, Dae Yong\|Kim, Tae Won\|Kim, Jee Hyun\|Im, Seok Ah\|Lee, Keun Seok\|Yun, Tak\|Jeong, Seung-Yong\|Choi, Hyo Seong\|Lim, Seok-Byung\|Chang, Hee Jin\|Jung, Kyung Hae
PMID:	20888703

1017.
Journal:	Jpn J Clin Oncol. 2011 Feb;41(2):165-71.
Title:	The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissues.
Author:	Okayama, Naoko\|Nishioka, Mitsuaki\|Hazama, Shoichi\|Sakai, Kouhei\|Suehiro, Yutaka\|Maekawa, Masato\|Sakamoto, Jun-ichi\|Iwamoto, Shigeyoshi\|Kato, Takeshi\|Mishima, Hideyuki\|Oka, Masaaki\|Hinoda, Yuji
PMID:	20926413

1018.
Journal:	Int J Cancer. 2011 Jun 1;128(11):2726-34.
Title:	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.
Author:	Slattery, Martha L\|Curtin, Karen\|Poole, Elizabeth M\|Duggan, David J\|Samowitz, Wade S\|Peters, Ulrike\|Caan, Bette J\|Potter, John D\|Ulrich, Cornelia M
PMID:	20949557

1019.
Journal:	Oncogene. 2011 Feb 3;30(5):561-74.
Title:	Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab.
Author:	Dunn, E F\|Iida, M\|Myers, R A\|Campbell, D A\|Hintz, K A\|Armstrong, E A\|Li, C\|Wheeler, D L
PMID:	20956938

1020.
Journal:	Cancer Chemother Pharmacol. 2011 Aug;68(2):317-23.
Title:	Clinical impact of K-ras mutation in colorectal cancer patients treated with adjuvant FOLFOX.
Author:	Chang, Myung Hee\|Lee, In Kyu\|Si, Yoon\|Lee, Kyu Sang\|Woo, In-Sook\|Byun, Jae Ho
PMID:	20972872

1021.
Journal:	Cytopathology. 2011 Dec;22(6):358-64.
Title:	KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.
Author:	Pang, N K B\|Nga, M E\|Chin, S Y\|Ismail, T M\|Lim, G L\|Soong, R\|Salto-Tellez, M
PMID:	21029218

1022.
Journal:	J Clin Pathol. 2011 Jan;64(1):30-6.
Title:	Sensitive multiplex detection of KRAS codons 12 and 13 mutations in paraffin-embedded tissue specimens.
Author:	Laosinchai-Wolf, Walairat\|Ye, Fei\|Tran, Vu\|Yang, Zhe\|White, Roxanna\|Bloom, Kenneth\|Choppa, Paul\|Labourier, Emmanuel
PMID:	21030527

1023.
Journal:	J Surg Oncol. 2011 Jan 1;103(1):25-33.
Title:	Genetic alterations of K-ras may reflect prognosis in stage III colon cancer patients below 60 years of age.
Author:	Onozato, Wataru\|Yamashita, Keishi\|Yamashita, Kazuya\|Kuba, Tatsuru\|Katoh, Hiroshi\|Nakamura, Takatoshi\|Sato, Takeo\|Ihara, Atsushi\|Okayasu, Isao\|Watanabe, Masahiko
PMID:	21031422

1024.
Journal:	Mutat Res. 2011 Jan 10;706(1-2):13-20.
Title:	Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Wolff, Roger K
PMID:	21035469

1025.
Journal:	Gut. 2011 Mar;60(3):397-411.
Title:	Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field.
Author:	Ogino, Shuji\|Chan, Andrew T\|Fuchs, Charles S\|Giovannucci, Edward
PMID:	21036793

1026.
Journal:	Carcinogenesis. 2011 Mar;32(3):318-26.
Title:	Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-beta-signaling pathway.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21088106

1027.
Journal:	Annu Rev Pathol. 2011;6:479-507.
Title:	Molecular genetics of colorectal cancer.
Author:	Fearon, Eric R
PMID:	21090969

1028.
Journal:	Cancer Biol Ther. 2011 Jan 15;11(2):177-83. Epub 2011 Jan 15.
Title:	Co-expression of matrix metalloproteinase-7 (MMP-7) and phosphorylated insulin growth factor receptor I (pIGF-1R) correlates with poor prognosis in patients with wild-type KRAS treated with cetuximab or panitumumab: a GEMCAD study.
Author:	Horndler, Carlos\|Gallego, Rosa\|Garcia-Albeniz, Xabier\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Jimeno, Mireya\|Ortego, Javier\|Codony-Servat, Jordi\|Fernandez-Martos, Carlos\|Calatrava, Ana\|Marin-Aguilera, Mercedes\|Munoz, Jenifer\|Castellvi-Be
PMID:	21099348

1029.
Journal:	Tumour Biol. 2011 Apr;32(2):417-24.
Title:	Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab.
Author:	Garcia-Albeniz, Xabier\|Pericay, Carles\|Alonso-Espinaco, Virginia\|Alonso, Vicente\|Escudero, Pilar\|Fernandez-Martos, Carlos\|Gallego, Rosa\|Gascon, Pere\|Castellvi-Bel, Sergi\|Maurel, Joan
PMID:	21104178

1030.
Journal:	Jpn J Clin Oncol. 2011 Feb;41(2):239-44.
Title:	Biased discordance of KRAS mutation detection in archived colorectal cancer specimens between the ARMS-Scorpion method and direct sequencing.
Author:	Bando, Hideaki\|Tsuchihara, Katsuya\|Yoshino, Takayuki\|Kojima, Motohiro\|Ogasawara, Naomi\|Fukushima, Hiraku\|Ochiai, Atsushi\|Ohtsu, Atsushi\|Esumi, Hiroyasu
PMID:	21113056

1031.
Journal:	Ann Oncol. 2011 May;22(5):1141-6.
Title:	Early magnesium modifications as a surrogate marker of efficacy of cetuximab-based anticancer treatment in KRAS wild-type advanced colorectal cancer patients.
Author:	Vincenzi, B\|Galluzzo, S\|Santini, D\|Rocci, L\|Loupakis, F\|Correale, P\|Addeo, R\|Zoccoli, A\|Napolitano, A\|Graziano, F\|Ruzzo, A\|Falcone, A\|Francini, G\|Dicuonzo, G\|Tonini, G
PMID:	21115601

1032.
Journal:	Cancer Res. 2011 Jan 15;71(2):445-53.
Title:	MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy.
Author:	Yoon, Juyong\|Koo, Kyoung-Hwa\|Choi, Kang-Yell
PMID:	21118963

1033.
Journal:	Cancer Causes Control. 2011 Feb;22(2):301-9.
Title:	MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Suzuki, Maiko\|Yamauchi, Mai\|Hayashi, Marika\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21140203

1034.
Journal:	Cancer Res. 2011 Feb 1;71(3):1071-80.
Title:	Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17.
Author:	Van Schaeybroeck, Sandra\|Kyula, Joan N\|Fenton, Audrey\|Fenning, Catherine S\|Sasazuki, Takehiko\|Shirasawa, Senji\|Longley, Daniel B\|Johnston, Patrick G
PMID:	21148749

1035.
Journal:	Cancer Sci. 2011 Jan;102(1):18-24.
Title:	Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes.
Author:	Kaneda, Atsushi\|Yagi, Koichi
PMID:	21159060

1036.
Journal:	Lancet Oncol. 2011 Jun;12(6):594-603.
Title:	KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.
Author:	De Roock, Wendy\|De Vriendt, Veerle\|Normanno, Nicola\|Ciardiello, Fortunato\|Tejpar, Sabine
PMID:	21163703

1037.
Journal:	Oncol Rep. 2011 Mar;25(3):789-94.
Title:	Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author:	Aoyagi, Haruhiko\|Iida, Satoru\|Uetake, Hiroyuki\|Ishikawa, Toshiaki\|Takagi, Yoko\|Kobayashi, Hirotoshi\|Higuchi, Tetsuro\|Yasuno, Masamichi\|Enomoto, Masayuki\|Sugihara, Kenichi
PMID:	21174064

1038.
Journal:	Int J Colorectal Dis. 2011 Feb;26(2):173-81.
Title:	Health-related quality of life and colorectal cancer-specific symptoms in patients with chemotherapy-refractory metastatic disease treated with panitumumab.
Author:	Odom, Dawn\|Barber, Beth\|Bennett, Lee\|Peeters, Marc\|Zhao, Zhongyun\|Kaye, James\|Wolf, Michael\|Wiezorek, Jeffrey
PMID:	21190026

1039.
Journal:	Cancer Res. 2011 Mar 1;71(5):1520-5.
Title:	Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.
Author:	Fischer, Marcus\|Yen, Wan-Ching\|Kapoun, Ann M\|Wang, Min\|O'Young, Gilbert\|Lewicki, John\|Gurney, Austin\|Hoey, Timothy
PMID:	21193546

1040.
Journal:	Cancer Res. 2011 Jan 1;71(1):206-15.
Title:	Activation and involvement of Ral GTPases in colorectal cancer.
Author:	Martin, Timothy D\|Samuel, Jonathan C\|Routh, Elizabeth D\|Der, Channing J\|Yeh, Jen Jen
PMID:	21199803

1041.
Journal:	Ann Intern Med. 2011 Jan 4;154(1):37-49.
Title:	Systematic review: Anti-epidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancer.
Author:	Dahabreh, Issa J\|Terasawa, Teruhiko\|Castaldi, Peter J\|Trikalinos, Thomas A
PMID:	21200037

1042.
Journal:	Genes Chromosomes Cancer. 2011 Mar;50(3):196-206.
Title:	MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype.
Author:	Slattery, Martha L\|Wolff, Erica\|Hoffman, Michael D\|Pellatt, Daniel F\|Milash, Brett\|Wolff, Roger K
PMID:	21213373

1043.
Journal:	Mol Cancer Ther. 2011 Mar;10(3):558-65.
Title:	PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors.
Author:	Janku, Filip\|Tsimberidou, Apostolia M\|Garrido-Laguna, Ignacio\|Wang, Xuemei\|Luthra, Rajyalakshmi\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Moroney, John W\|Piha-Paul, Sarina A\|Wheler, Jennifer J\|Moulder, Stacy L\|Fu, Siqing\|Kurzrock, Razelle
PMID:	21216929

1044.
Journal:	Nat Rev Clin Oncol. 2011 Jan;8(1):1.
Title:	Genetics: In colorectal cancer, not all KRAS mutations are created equal.
Author:	Kirk, Rebecca
PMID:	21218523

1045.
Journal:	J Mol Diagn. 2011 Jan;13(1):64-73.
Title:	Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping.
Author:	Arcila, Maria\|Lau, Christopher\|Nafa, Khedoudja\|Ladanyi, Marc
PMID:	21227396

1046.
Journal:	Am J Clin Pathol. 2011 Feb;135(2):245-52.
Title:	KRAS gene mutation in colorectal cancer is correlated with increased proliferation and spontaneous apoptosis.
Author:	Liu, Xiuli\|Jakubowski, Maureen\|Hunt, Jennifer L
PMID:	21228365

1047.
Journal:	Virchows Arch. 2011 Feb;458(2):213-9.
Title:	Downregulation of the hedgehog receptor PTCH1 in colorectal serrated adenocarcinomas is not caused by PTCH1 mutations.
Author:	Stefanius, Karoliina\|Kantola, Tiina\|Tuomisto, Anne\|Vahteristo, Pia\|Karttunen, Tuomo J\|Aaltonen, Lauri A\|Makinen, Markus J\|Karhu, Auli
PMID:	21234763

1048.
Journal:	Clin Cancer Res. 2011 Mar 1;17(5):1122-30.
Title:	KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.
Author:	Tie, Jeanne\|Lipton, Lara\|Desai, Jayesh\|Gibbs, Peter\|Jorissen, Robert N\|Christie, Michael\|Drummond, Katharine J\|Thomson, Benjamin N J\|Usatoff, Valery\|Evans, Peter M\|Pick, Adrian W\|Knight, Simon\|Carne, Peter W G\|Berry, Roger\|Polglase, Adrian\|McMurrick, Paul
PMID:	21239505

1049.
Journal:	Lab Invest. 2011 May;91(5):788-98.
Title:	Rapid detection of low-abundance K-ras mutation in stools of colorectal cancer patients using chip-based temperature gradient capillary electrophoresis.
Author:	Zhang, Huidan\|Wang, Xiaonan\|Ma, Qian\|Zhou, Zhe\|Fang, Jin
PMID:	21242956

1050.
Journal:	Am J Gastroenterol. 2011 Feb;106(2):190-8.
Title:	The American College of Gastroenterology Emily Couric Lecture--the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived?
Author:	Ahnen, Dennis J
PMID:	21266962

1051.
Journal:	Anticancer Res. 2011 Jan;31(1):255-61.
Title:	A phase II study of capecitabine, oxaliplatin, bevacizumab and cetuximab in the treatment of metastatic colorectal cancer.
Author:	Wong, Nan Soon\|Fernando, Nishan H\|Nixon, Andrew B\|Cushman, Stephanie\|Aklilu, Mebea\|Bendell, Johanna C\|Morse, Michael A\|Blobe, Gerard C\|Ashton, Jill\|Pang, Herbert\|Hurwitz, Herbert I
PMID:	21273607

1052.
Journal:	FEBS Lett. 2011 Feb 18;585(4):693-9.
Title:	The Evi1, microRNA-143, K-Ras axis in colon cancer.
Author:	Gao, Jin-Song\|Zhang, Yingjie\|Tang, Xiaoli\|Tucker, Lynne D\|Tarwater, Patrick M\|Quesenberry, Peter J\|Rigoutsos, Isidore\|Ramratnam, Bharat
PMID:	21276449

1053.
Journal:	J Visc Surg. 2011 Feb;148(1):12-8.
Title:	Targeted biotherapy in metastatic colorectal carcinoma: Current practice.
Author:	Cacheux, W\|Le Tourneau, C\|Baranger, B\|Mignot, L\|Mariani, P
PMID:	21277276

1054.
Journal:	PLoS One. 2011 Jan 20;6(1):e15980.
Title:	Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in >/= 2 line cetuximab-based therapy of colorectal cancer patients.
Author:	Saridaki, Zacharenia\|Tzardi, Maria\|Papadaki, Chara\|Sfakianaki, Maria\|Pega, Fraga\|Kalikaki, Aristea\|Tsakalaki, Eleftheria\|Trypaki, Maria\|Messaritakis, Ippokratis\|Stathopoulos, Efstathios\|Mavroudis, Dimitris\|Georgoulias, Vassilis\|Souglakos, John
PMID:	21283802

1055.
Journal:	Anticancer Drugs. 2011 Jun;22(5):384-91.
Title:	Novel modalities in the treatment of patients with KRAS-mutated colorectal cancer.
Author:	Dimou, Anastasios\|Syrigos, Konstantinos\|Saif, Muhammad Wasif
PMID:	21285867

1056.
Journal:	Br J Cancer. 2011 Mar 1;104(5):856-62.
Title:	BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer.
Author:	Yokota, T\|Ura, T\|Shibata, N\|Takahari, D\|Shitara, K\|Nomura, M\|Kondo, C\|Mizota, A\|Utsunomiya, S\|Muro, K\|Yatabe, Y
PMID:	21285991

1057.
Journal:	Int J Colorectal Dis. 2011 Jul;26(7):823-33.
Title:	Cetuximab and panitumumab in KRAS wild-type colorectal cancer: a meta-analysis.
Author:	Petrelli, Fausto\|Borgonovo, Karen\|Cabiddu, Mary\|Ghilardi, Mara\|Barni, Sandro
PMID:	21286919

1058.
Journal:	Cancer Genomics Proteomics. 2011 Jan-Feb;8(1):15-8.
Title:	BRAF p.Val600Glu (V600E) somatic mutation is mainly associated with MSS phenotype in metastatic colorectal cancer.
Author:	Qiu, Jinghua\|Compagnone, Marion\|Laibe, Sophy\|Lagarde, Arnaud\|Goncalves, Anthony\|Turrini, Olivier\|Xerri, Luc\|Monges, Genevieve\|Olschwang, Sylviane
PMID:	21289333

1059.
Journal:	J Clin Oncol. 2011 Mar 10;29(8):1050-8.
Title:	Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104--a randomized trial of the German AIO CRC study group.
Author:	Moosmann, Nicolas\|von Weikersthal, Ludwig Fischer\|Vehling-Kaiser, Ursula\|Stauch, Martina\|Hass, Holger G\|Dietzfelbinger, Herrmann\|Oruzio, Daniel\|Klein, Stefan\|Zellmann, Klaus\|Decker, Thomas\|Schulze, Mathias\|Abenhardt, Wolfgang\|Puchtler, Gerhard\|Kappauf, He
PMID:	21300933

1060.
Journal:	Genes Chromosomes Cancer. 2011 May;50(5):307-12.
Title:	Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
Author:	Vaughn, Cecily P\|Zobell, Scott D\|Furtado, Larissa V\|Baker, Christine L\|Samowitz, Wade S
PMID:	21305640

1061.
Journal:	Clin Cancer Res. 2011 Mar 15;17(6):1452-62.
Title:	STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.
Author:	Morikawa, Teppei\|Baba, Yoshifumi\|Yamauchi, Mai\|Kuchiba, Aya\|Nosho, Katsuhiko\|Shima, Kaori\|Tanaka, Noriko\|Huttenhower, Curtis\|Frank, David A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21310826

1062.
Journal:	Hum Pathol. 2011 Jul;42(7):1047-52.
Title:	A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author:	Pancione, Massimo\|Di Blasi, Arturo\|Sabatino, Lina\|Fucci, Alessandra\|Dalena, Anna Maria\|Palombi, Natalia\|Carotenuto, Pietro\|Aquino, Gabriella\|Daniele, Bruno\|Normanno, Nicola\|Colantuoni, Vittorio
PMID:	21315413

1063.
Journal:	Methods Mol Biol. 2011;720:339-48.
Title:	Polyamine transport systems in mammalian cells and tissues.
Author:	Uemura, Takeshi\|Gerner, Eugene W
PMID:	21318884

1064.
Journal:	Anal Chem. 2011 Mar 15;83(6):2301-9.
Title:	High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system.
Author:	Dharmasiri, Udara\|Njoroge, Samuel K\|Witek, Malgorzata A\|Adebiyi, Morayo G\|Kamande, Joyce W\|Hupert, Mateusz L\|Barany, Francis\|Soper, Steven A
PMID:	21319808

1065.
Journal:	Nat Rev Clin Oncol. 2011 Feb 15;8(4):222-32.
Title:	Implementing prognostic and predictive biomarkers in CRC clinical trials.
Author:	Van Schaeybroeck, Sandra\|Allen, Wendy L\|Turkington, Richard C\|Johnston, Patrick G
PMID:	21321566

1066.
Journal:	Cancer Chemother Pharmacol. 2011 Apr;67(4):729-39.
Title:	Statins are logical candidates for overcoming limitations of targeting therapies on malignancy: their potential application to gastrointestinal cancers.
Author:	Shimoyama, Shouji
PMID:	21327931

1067.
Journal:	Mod Pathol. 2011 May;24(5):729-38.
Title:	Clinicopathological and molecular characterization of colorectal micropapillary carcinoma.
Author:	Verdu, Montse\|Roman, Ruth\|Calvo, Miquel\|Rodon, Natalia\|Garcia, Beatriz\|Gonzalez, Marta\|Vidal, August\|Puig, Xavier
PMID:	21336262

1068.
Journal:	Cancer Chemother Pharmacol. 2011 Oct;68(4):1045-55.
Title:	Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer.
Author:	Park, Jin Hyun\|Han, Sae-Won\|Oh, Do-Youn\|Im, Seock-Ah\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kim, Tae-You\|Bang, Yung-Jue\|Park, Jae-Gahb
PMID:	21340604

1069.
Journal:	Ann Surg Oncol. 2011 Dec;18(13):3694-700.
Title:	Molecular profiling of colon tumors: the search for clinically relevant biomarkers of progression, prognosis, therapeutics, and predisposition.
Author:	Bacolod, Manny D\|Barany, Francis
PMID:	21347779

1070.
Journal:	J Mol Diagn. 2011 Mar;13(2):199-205.
Title:	SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.
Author:	Farina Sarasqueta, Arantza\|Moerland, Elna\|de Bruyne, Hanneke\|de Graaf, Henk\|Vrancken, Tamara\|van Lijnschoten, Gesina\|van den Brule, Adriaan J C
PMID:	21354055

1071.
Journal:	Discov Med. 2011 Feb;11(57):95-105.
Title:	The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer.
Author:	Yarom, Nirit\|Jonker, Derek J
PMID:	21356164

1072.
Journal:	Br J Cancer. 2011 Mar 15;104(6):1020-6.
Title:	KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.
Author:	Knijn, N\|Mekenkamp, L J M\|Klomp, M\|Vink-Borger, M E\|Tol, J\|Teerenstra, S\|Meijer, J W R\|Tebar, M\|Riemersma, S\|van Krieken, J H J M\|Punt, C J A\|Nagtegaal, I D
PMID:	21364579

1073.
Journal:	J Mol Signal. 2011 Mar 3;6:2.
Title:	Activation of K-RAS by co-mutation of codons 19 and 20 is transforming.
Author:	Naguib, Adam\|Wilson, Catherine H\|Adams, David J\|Arends, Mark J
PMID:	21371307

1074.
Journal:	Clin Exp Metastasis. 2011 Jun;28(5):427-35.
Title:	Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors.
Author:	Goranova, Teodora Evgenieva\|Ohue, Masayuki\|Shimoharu, Yutaro\|Kato, Kikuya
PMID:	21380628

1075.
Journal:	J Clin Oncol. 2011 Apr 1;29(10):1261-70.
Title:	Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer.
Author:	Hutchins, Gordon\|Southward, Katie\|Handley, Kelly\|Magill, Laura\|Beaumont, Claire\|Stahlschmidt, Jens\|Richman, Susan\|Chambers, Philip\|Seymour, Matthew\|Kerr, David\|Gray, Richard\|Quirke, Philip
PMID:	21383284

1076.
Journal:	World J Gastroenterol. 2011 Feb 14;17(6):809-16.
Title:	Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients.
Author:	Shen, Hong\|Yuan, Ying\|Hu, Han-Guang\|Zhong, Xian\|Ye, Xiao-Xian\|Li, Mo-Dan\|Fang, Wei-Jia\|Zheng, Shu
PMID:	21390154

1077.
Journal:	J Natl Cancer Inst. 2011 Apr 20;103(8):674-88.
Title:	Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.
Author:	Lee, Jeeyun\|Lee, Inkyoung\|Han, Boram\|Park, Joon Oh\|Jang, Jiryeon\|Park, Chaehwa\|Kang, Won Ki
PMID:	21398618

1078.
Journal:	PLoS One. 2011 Mar 8;6(3):e17384.
Title:	In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.
Author:	Miller, Sharon J\|Joshi, Bishnu P\|Feng, Ying\|Gaustad, Adam\|Fearon, Eric R\|Wang, Thomas D
PMID:	21408169

1079.
Journal:	Exp Oncol. 2011 Mar;33(1):28-32.
Title:	Is there any association between TACSTD2, KIAA1253, Ku70 and mutant KRAS gene expression and clinical-pathological features of colorectal cancer?
Author:	Ghezzi, T L\|Brum, I S\|Biolchi, V\|Garicochea, B\|Fillmann, L S\|Corleta, O C
PMID:	21423092

1080.
Journal:	Mod Pathol. 2011 Jul;24(7):1015-22.
Title:	Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.
Author:	Kriegl, Lydia\|Neumann, Jens\|Vieth, Michael\|Greten, Florian R\|Reu, Simone\|Jung, Andreas\|Kirchner, Thomas
PMID:	21423154

1081.
Journal:	Oncol Rep. 2011 Jun;25(6):1691-7.
Title:	KRAS, BRAF and PIK3CA mutations in human colorectal cancer: relationship with metastatic colorectal cancer.
Author:	Li, Hong-Tao\|Lu, Yuan-Yuan\|An, Yan-Xin\|Wang, Xin\|Zhao, Qing-Chuan
PMID:	21424126

1082.
Journal:	Cancer. 2011 Apr 1;117(7):1399-408.
Title:	Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Hayashi, Marika\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21425139

1083.
Journal:	Cancer J. 2011 Mar-Apr;17(2):114-26.
Title:	Molecular predictors of response to chemotherapy in colorectal cancer.
Author:	Dienstmann, Rodrigo\|Vilar, Eduardo\|Tabernero, Josep
PMID:	21427555

1084.
Journal:	Pathology. 2011 Apr;43(3):228-33.
Title:	Clinically important molecular features of Peruvian colorectal tumours: high prevalence of DNA mismatch repair deficiency and low incidence of KRAS mutations.
Author:	Egoavil, C M\|Montenegro, P\|Soto, J L\|Casanova, L\|Sanchez-Lihon, J\|Castillejo, M I\|Martinez-Canto, A\|Perez-Carbonell, L\|Castillejo, A\|Guarinos, C\|Barbera, V M\|Jover, R\|Paya, A\|Alenda, C
PMID:	21436632

1085.
Journal:	Patholog Res Int. 2011 Mar 15;2011:219309.
Title:	Impact of KRAS Mutations on Management of Colorectal Carcinoma.
Author:	Sullivan, Kevin M\|Kozuch, Peter S
PMID:	21437184

1086.
Journal:	Oncologist. 2011;16(4):467-78.
Title:	External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds.
Author:	Bellon, Ellen\|Ligtenberg, Marjolijn J L\|Tejpar, Sabine\|Cox, Karen\|de Hertogh, Gert\|de Stricker, Karin\|Edsjo, Anders\|Gorgoulis, Vassilis\|Hofler, Gerald\|Jung, Andreas\|Kotsinas, Athanassios\|Laurent-Puig, Pierre\|Lopez-Rios, Fernando\|Hansen, Tine Plato\|Rouleau
PMID:	21441573

1087.
Journal:	Sci Signal. 2011 Mar 29;4(166):ra17.
Title:	Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Newman, Scott\|Dry, Jonathan R\|Hampson, Mark\|Edwards, Paul A W\|Smith, Paul D\|Cook, Simon J
PMID:	21447798

1088.
Journal:	Nat Rev Clin Oncol. 2011 Mar 8;8(4):193.
Title:	Targeted therapies: dasatinib sensitizes KRAS-mutant colorectal cancer tumors to cetuximab.
Author:	Hutchinson, Lisa
PMID:	21451492

1089.
Journal:	Pathol Oncol Res. 2011 Dec;17(4):819-25.
Title:	High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
Author:	Naghibalhossaini, Fakhraddin\|Hosseini, Hamideh Mahmoodzadeh\|Mokarram, Pooneh\|Zamani, Mozhdeh
PMID:	21455633

1090.
Journal:	Nutr Cancer. 2011;63(3):357-66.
Title:	Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women.
Author:	Curtin, Karen\|Samowitz, Wade S\|Ulrich, Cornelia M\|Wolff, Roger K\|Herrick, Jennifer S\|Caan, Bette J\|Slattery, Martha L
PMID:	21462086

1091.
Journal:	Cancer Res. 2011 May 15;71(10):3635-48.
Title:	The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.
Author:	LaBonte, Melissa J\|Wilson, Peter M\|Fazzone, Will\|Russell, Jared\|Louie, Stan G\|El-Khoueiry, Anthony\|Lenz, Heinz-Josef\|Ladner, Robert D
PMID:	21464044

1092.
Journal:	Cell Oncol (Dordr). 2011 Aug;34(4):307-13.
Title:	Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737.
Author:	Raats, Danielle A E\|de Bruijn, Menno T\|Steller, Ernst J A\|Emmink, Benjamin L\|Borel-Rinkes, Inne H M\|Kranenburg, Onno
PMID:	21468686

1093.
Journal:	Cancer Causes Control. 2011 Jul;22(7):955-63.
Title:	Variation in the CYP19A1 gene and risk of colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Kadlubar, Susan\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21479914

1094.
Journal:	Anal Cell Pathol (Amst). 2011;34(1-2):61-6.
Title:	Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.
Author:	Richman, Susan D\|Chambers, Philip\|Seymour, Matthew T\|Daly, Catherine\|Grant, Sophie\|Hemmings, Gemma\|Quirke, Philip
PMID:	21483104

1095.
Journal:	Anticancer Res. 2011 Apr;31(4):1379-85.
Title:	Combined KRAS and TP53 mutation status is not predictive in CAPOX-treated metastatic colorectal cancer.
Author:	De Bruijn, Menno T\|Raats, Danielle A E\|Tol, Jolien\|Hinrichs, John\|Teerenstra, Steven\|Punt, Cornelis J A\|Rinkes, Inne H M Borel\|Kranenburg, Onno
PMID:	21508389

1096.
Journal:	Cancer. 2011 May 1;117(9):1847-54.
Title:	DNA methylation predicts recurrence from resected stage III proximal colon cancer.
Author:	Ahn, Joong Bae\|Chung, Woon Bok\|Maeda, Osamu\|Shin, Sang Joon\|Kim, Hyun Soo\|Chung, Hyun Chul\|Kim, Nam Kyu\|Issa, Jean-Pierre J
PMID:	21509761

1097.
Journal:	Curr Biol. 2011 May 10;21(9):779-86.
Title:	Amphiregulin exosomes increase cancer cell invasion.
Author:	Higginbotham, James N\|Demory Beckler, Michelle\|Gephart, Jonathan D\|Franklin, Jeffrey L\|Bogatcheva, Galina\|Kremers, Gert-Jan\|Piston, David W\|Ayers, Gregory D\|McConnell, Russell E\|Tyska, Matthew J\|Coffey, Robert J
PMID:	21514161

1098.
Journal:	Mod Pathol. 2011 Aug;24(8):1090-100.
Title:	Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls.
Author:	Lamy, Aude\|Blanchard, France\|Le Pessot, Florence\|Sesboue, Richard\|Di Fiore, Frederic\|Bossut, Jessie\|Fiant, Elodie\|Frebourg, Thierry\|Sabourin, Jean-Christophe
PMID:	21516079

1099.
Journal:	JAMA. 2011 Apr 27;305(16):1685-94.
Title:	Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Meyerhardt, Jeffrey A\|Shima, Kaori\|Nosho, Katsuhiko\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21521850

1100.
Journal:	Arch Pathol Lab Med. 2011 May;135(5):578-87.
Title:	Molecular diagnostics of colorectal cancer.
Author:	Bedeir, Ahmed\|Krasinskas, Alyssa M
PMID:	21526956

1101.
Journal:	Clin Cancer Res. 2011 Jun 1;17(11):3551-7.
Title:	Detection of tumor DNA at the margins of colorectal cancer liver metastasis.
Author:	Holdhoff, Matthias\|Schmidt, Kerstin\|Diehl, Frank\|Aggrawal, Nishant\|Angenendt, Philipp\|Romans, Katharine\|Edelstein, Daniel L\|Torbenson, Michael\|Kinzler, Kenneth W\|Vogelstein, Bert\|Choti, Michael A\|Diaz, Luis A Jr
PMID:	21531819

1102.
Journal:	Pathol Res Pract. 2011 Jun 15;207(6):399-402.
Title:	Morphological and molecular heterogeneity in colorectal neoplasms with K-RAS mutation. A report of two cases.
Author:	Bosmuller, Hans\|Kranewitter, Wolfgang\|Webersinke, Gerald\|Rumpold, Holger\|Hackl, Margit\|Fend, Falko
PMID:	21536390

1103.
Journal:	Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5.
Title:	Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.
Author:	Curtin, Karen\|Ulrich, Cornelia M\|Samowitz, Wade S\|Wolff, Roger K\|Duggan, David J\|Makar, Karen W\|Caan, Bette J\|Slattery, Martha L
PMID:	21537397

1104.
Journal:	Int J Colorectal Dis. 2011 Nov;26(11):1387-95.
Title:	Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.
Author:	Liou, Jyh-Ming\|Wu, Ming-Shiang\|Shun, Chia-Tung\|Chiu, Han-Mo\|Chen, Mei-Jyh\|Chen, Chien-Chuan\|Wang, Hsiu-Po\|Lin, Jaw-Town\|Liang, Jin-Tung
PMID:	21553007

1105.
Journal:	BMC Res Notes. 2011 May 10;4:140.
Title:	Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models.
Author:	Matsuo, Teppei\|Nishizuka, Satoshi S\|Ishida, Kazushige\|Iwaya, Takeshi\|Ikeda, Miyuki\|Wakabayashi, Go
PMID:	21554739

1106.
Journal:	Expert Opin Biol Ther. 2011 Jul;11(7):937-49.
Title:	Cetuximab in the treatment of patients with colorectal cancer.
Author:	Garrett, Christopher R\|Eng, Cathy
PMID:	21557708

1107.
Journal:	Clin Cancer Res. 2011 May 15;17(10):3469-77.
Title:	Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Author:	Grimminger, Peter P\|Danenberg, Peter\|Dellas, Kathrin\|Arnold, Dirk\|Rodel, Claus\|Machiels, Jean-Pascal\|Haustermans, Karin\|Debucquoy, Annelies\|Velenik, Vaneja\|Sempoux, Christine\|Bracko, Matej\|Holscher, Arnulf H\|Semrau, Robert\|Yang, Dongyun\|Danenberg, Kathlee
PMID:	21558395

1108.
Journal:	Clin Chim Acta. 2011 Aug 17;412(17-18):1578-81.
Title:	KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing.
Author:	French, Deborah\|Smith, Andrew\|Powers, Martin P\|Wu, Alan H B
PMID:	21575616

1109.
Journal:	Int J Colorectal Dis. 2011 Oct;26(10):1241-8.
Title:	Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case reports.
Author:	Macedo, Mariana Petaccia\|Andrade, Louise De Brot\|Coudry, Renata\|Crespo, Rodrigo\|Gomes, Marina\|Lisboa, Bianca Cristina Garcia\|Aguiar, Samuel Jr\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|Cunha, Isabela Werneck
PMID:	21603900

1110.
Journal:	Clin Colorectal Cancer. 2011 Mar 1;10(1):63-9.
Title:	Effect of KRAS mutational status in advanced colorectal cancer on the outcomes of anti-epidermal growth factor receptor monoclonal antibody therapy: a systematic review and meta-analysis.
Author:	Lin, Albert Y\|Buckley, Nicholas S\|Lu, An-Ting T\|Kouzminova, Natalia B\|Salpeter, Shelley R
PMID:	21609938

1111.
Journal:	Inflamm Bowel Dis. 2011 Sep;17(9):1966-70.
Title:	Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer.
Author:	Sanchez, Julian A\|Dejulius, Kathryn L\|Bronner, Mary\|Church, James M\|Kalady, Matthew F
PMID:	21618350

1112.
Journal:	Cancer Lett. 2011 Sep 1;308(1):118-21.
Title:	Stromal cells do not share KRAS mutations that the epithelial component harbors in colorectal carcinomas.
Author:	Baloglu, Huseyin\|Yigit, Nuri
PMID:	21624768

1113.
Journal:	Clin Cancer Res. 2011 Jul 15;17(14):4901-14.
Title:	Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.
Author:	Molinari, Francesca\|Felicioni, Lara\|Buscarino, Michela\|De Dosso, Sara\|Buttitta, Fiamma\|Malatesta, Sara\|Movilia, Alessandra\|Luoni, Marco\|Boldorini, Renzo\|Alabiso, Oscar\|Girlando, Salvatore\|Soini, Barbara\|Spitale, Alessandra\|Di Nicolantonio, Federica\|Salett
PMID:	21632860

1114.
Journal:	Clin Ther. 2011 Apr;33(4):482-97.
Title:	Cost-effectiveness of targeted therapy with cetuximab in patients with K-ras wild-type colorectal cancer presenting with initially unresectable metastases limited to the liver in a German setting.
Author:	Asseburg, Christian\|Frank, Martin\|Kohne, Claus-Henning\|Hartmann, Jorg Thomas\|Griebsch, Ingolf\|Mohr, Andrea\|Osowski, Ulrike\|Schulten, Jeltje\|Mittendorf, Thomas
PMID:	21635994

1115.
Journal:	Lancet. 2011 Jun 18;377(9783):2103-14.
Title:	Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial.
Author:	Maughan, Timothy S\|Adams, Richard A\|Smith, Christopher G\|Meade, Angela M\|Seymour, Matthew T\|Wilson, Richard H\|Idziaszczyk, Shelley\|Harris, Rebecca\|Fisher, David\|Kenny, Sarah L\|Kay, Edward\|Mitchell, Jenna K\|Madi, Ayman\|Jasani, Bharat\|James, Michelle D\|Brid
PMID:	21641636

1116.
Journal:	J Clin Oncol. 2011 Jul 1;29(19):2728-9.
Title:	Impact of KRAS and BRAF gene mutations on targeted therapies in colorectal cancer.
Author:	Bass, Adam
PMID:	21646605

1117.
Journal:	J Clin Oncol. 2011 Jul 1;29(19):2675-82.
Title:	Impact of KRAS and BRAF Gene Mutation Status on Outcomes From the Phase III AGITG MAX Trial of Capecitabine Alone or in Combination With Bevacizumab and Mitomycin in Advanced Colorectal Cancer.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Weickhardt, Andrew\|Townsend, Amanda R\|Wrin, Joseph W\|Chua, Ann\|Shivasami, Aravind\|Cummins, Michelle M\|Murone, Carmel\|Tebbutt, Niall C
PMID:	21646616

1118.
Journal:	Magy Onkol. 2011 Jun;55(2):99-100, 102-4.
Title:	[Effect of KRAS mutation status on the efficiency of Avastin therapy of colorectal cancer].
Author:	Hegedus, Zita\|Barbai, Tamas\|Tatrai, Peter\|Hegedus, Balazs\|Kiss, Andras\|Raso, Erzsebet\|Bodoky, Gyorgy
PMID:	21655475

1119.
Journal:	J Pathol. 2011 Nov;225(3):336-43.
Title:	Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.
Author:	Zlobec, Inti\|Bihl, Michel\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	21660972

1120.
Journal:	Hepatogastroenterology. 2011 Mar-Apr;58(106):411-6.
Title:	Heterogeneity in primary colorectal cancer and its corresponding metastases: a potential reason of EGFR-targeted therapy failure?
Author:	Li, Zhongqi\|Jin, Ketao\|Lan, Huanrong\|Teng, Lisong
PMID:	21661405

1121.
Journal:	Cancer Genet. 2011 May;204(5):245-51.
Title:	Correlation of polypoid colorectal adenocarcinoma with pre-existing adenomatous polyps and KRAS mutation.
Author:	Chen, Hui\|Lefferts, Joel A\|Schwab, Mary C\|Suriawinata, Arief A\|Tsongalis, Gregory J
PMID:	21665177

1122.
Journal:	Cancer Res. 2011 Aug 1;71(15):5144-53.
Title:	Inhibition of miR-193a expression by Max and RXRalpha activates K-Ras and PLAU to mediate distinct aspects of cellular transformation.
Author:	Iliopoulos, Dimitrios\|Rotem, Asaf\|Struhl, Kevin
PMID:	21670079

1123.
Journal:	J Surg Oncol. 2011 Nov 1;104(6):661-6.
Title:	The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy.
Author:	Lin, Jen-Kou\|Lin, An-Jen\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Yang, Shung-Haur\|Li, Anna Fen-Yau\|Chang, Shih-Ching
PMID:	21671463

1124.
Journal:	Clin Cancer Res. 2011 Aug 1;17(15):5161-9.
Title:	EGF61 polymorphism predicts complete pathologic response to cetuximab-based chemoradiation independent of KRAS status in locally advanced rectal cancer patients.
Author:	Hu-Lieskovan, Siwen\|Vallbohmer, Daniel\|Zhang, Wu\|Yang, Dongyun\|Pohl, Alexander\|Labonte, Melissa J\|Grimminger, Peter P\|Holscher, Arnulf H\|Semrau, Robert\|Arnold, Dirk\|Dellas, Kathrin\|Debucquoy, Annelies\|Haustermans, Karin\|Machiels, Jean-Pascal H\|Sempoux, Ch
PMID:	21673069

1125.
Journal:	Br J Cancer. 2011 Jul 12;105(2):281-7.
Title:	Molecular alterations associated with liver metastases development in colorectal cancer patients.
Author:	Bruin, S C\|He, Y\|Mikolajewska-Hanclich, I\|Liefers, G-J\|Klijn, C\|Vincent, A\|Verwaal, V J\|de Groot, K A\|Morreau, H\|van Velthuysen, M-L F\|Tollenaar, R A E M\|van 't Veer, L J
PMID:	21673680

1126.
Journal:	Sci Signal. 2011;4(170):er2.
Title:	A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Newman, Scott\|Dry, Jonathan R\|Hampson, Mark\|Edwards, Paul A W\|Smith, Paul D\|Cook, Simon J
PMID:	21674991

1127.
Journal:	Harefuah. 2011 May;150(5):447-50, 491.
Title:	[Identification of K-RAS mutations in colorectal cancer patients in Israel].
Author:	Segal, Gadi\|Liebermann, Nicky\|Klang, Shmuel\|Siegelmann-Daniel, Nava\|Beit-Or, Anat\|Klien, Baruch\|Shoushan-Gutman, Lior
PMID:	21678640

1128.
Journal:	Harefuah. 2011 May;150(5):451-2, 490.
Title:	[Personalized medicine--the future is already here].
Author:	Abadi-Korek, Ifat\|Shemer, Joshua
PMID:	21678641

1129.
Journal:	Drugs R D. 2011;11(2):101-11.
Title:	Use of bevacizumab in metastatic colorectal cancer: report from the Mexican opinion and analysis forum on colorectal cancer treatment with bevacizumab (September 2009).
Author:	Zinser-Sierra, Juan W\|Rodriguez-Ramirez, Saul\|Villalobos-Valencia, Ricardo\|Ramirez-Marquez, Marcelino
PMID:	21679003

1130.
Journal:	Cancer Prev Res (Phila). 2011 Nov;4(11):1808-15.
Title:	Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies.
Author:	Lee, Jung Eun\|Baba, Yoshifumi\|Ng, Kimmie\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji\|Chan, Andrew T
PMID:	21680706

1131.
Journal:	Int J Mol Sci. 2011;12(5):3191-204.
Title:	KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues.
Author:	Solassol, Jerome\|Ramos, Jeanne\|Crapez, Evelyne\|Saifi, Majda\|Mange, Alain\|Vianes, Evelyne\|Lamy, Pierre-Jean\|Costes, Valerie\|Maudelonde, Thierry
PMID:	21686179

1132.
Journal:	Br J Cancer. 2011 Jul 12;105(2):255-62.
Title:	EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer.
Author:	Algars, A\|Lintunen, M\|Carpen, O\|Ristamaki, R\|Sundstrom, J
PMID:	21694725

1133.
Journal:	PLoS One. 2011;6(6):e20919.
Title:	Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.
Author:	Al-Ghamdi, Saleh\|Albasri, Abdulkader\|Cachat, Julien\|Ibrahem, Salih\|Muhammad, Belal A\|Jackson, Darryl\|Nateri, Abdolrahman S\|Kindle, Karin B\|Ilyas, Mohammad
PMID:	21698197

1134.
Journal:	Genet Test Mol Biomarkers. 2011 Nov;15(11):831-4.
Title:	Comparison of KRAS mutation tests in colorectal cancer patients.
Author:	Hancer, Veysel Sabri\|Buyukdogan, Murat\|Turkmen, Ilknur\|Bassullu, Nuray\|Altug, Tuncay\|Diz-Kucukkaya, Reyhan\|Bulbul-Dogusoy, Gulen\|Demir, Gokhan
PMID:	21699410

1135.
Journal:	Gastroenterology. 2011 Sep;141(3):1003-1013.e1-10.
Title:	Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.
Author:	Feng, Ying\|Bommer, Guido T\|Zhao, Jenny\|Green, Maranne\|Sands, Evan\|Zhai, Yali\|Brown, Kelly\|Burberry, Aaron\|Cho, Kathleen R\|Fearon, Eric R
PMID:	21699772

1136.
Journal:	Virchows Arch. 2011 Aug;459(2):155-60.
Title:	Mutation analysis of KRAS prior to targeted therapy in colorectal cancer: development and evaluation of quality by a European external quality assessment scheme.
Author:	Dequeker, Elisabeth\|Ligtenberg, Marjolijn J L\|Vander Borght, Sara\|van Krieken, Johan H J M
PMID:	21701884

1137.
Journal:	J Mol Diagn. 2011 Jul;13(4):436-45.
Title:	KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers diagnostic and therapeutic implications.
Author:	Balschun, Katharina\|Haag, Jochen\|Wenke, Ann-Kathrin\|von Schonfels, Witigo\|Schwarz, Nicolas T\|Rocken, Christoph
PMID:	21704278

1138.
Journal:	Lung Cancer. 2011 Oct;74(1):7-11.
Title:	Do all lung adenocarcinomas follow a stepwise progression?
Author:	Yatabe, Yasushi\|Borczuk, Alain C\|Powell, Charles A
PMID:	21705107

1139.
Journal:	Cancer Biol Ther. 2011 Aug 1;12(3):239-51. Epub 2011 Aug 1.
Title:	Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer.
Author:	Gallant, Jean-Nicolas\|Allen, Joshua E\|Smith, Charles D\|Dicker, David T\|Wang, Wenge\|Dolloff, Nathan G\|Navaraj, Arunasalam\|El-Deiry, Wafik S
PMID:	21725213

1140.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):325-32.
Title:	Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
Author:	Inno, Alessandro\|Di Salvatore, Mariantonietta\|Cenci, Tonia\|Martini, Maurizio\|Orlandi, Armando\|Strippoli, Antonia\|Ferrara, Anna Maria\|Bagala, Cinzia\|Cassano, Alessandra\|Larocca, Luigi Maria\|Barone, Carlo
PMID:	21729677

1141.
Journal:	Clin Colorectal Cancer. 2011 Dec;10(4):279-89.
Title:	Development of molecular biomarkers in individualized treatment of colorectal cancer.
Author:	De Mattos-Arruda, Leticia\|Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	21729679

1142.
Journal:	Oncologist. 2011;16(8):1061-8.
Title:	KRAS and colorectal cancer: ethical and pragmatic issues in effecting real-time change in oncology clinical trials and practice.
Author:	Blanke, Charles D\|Goldberg, Richard M\|Grothey, Axel\|Mooney, Margaret\|Roach, Nancy\|Saltz, Leonard B\|Welch, John J\|Wood, William A\|Meropol, Neal J
PMID:	21737577

1143.
Journal:	Anticancer Res. 2011 Jun;31(6):2149-60.
Title:	Estimating preclinical efficacy targets utilizing cetuximab efficacy in KRAS mutant and wild-type colorectal cancer models.
Author:	Prewett, Marie\|Bassi, Rajiv\|Paz, Keren\|Amatulli, Michael\|Deevi, Dhanvanthri\|Li, Huiling\|Wang, Su\|Witte, Larry\|Samakoglu, Selda\|Tonra, James R
PMID:	21737635

1144.
Journal:	PLoS One. 2011;6(6):e21632.
Title:	Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.
Author:	Oikonomou, Eftychia\|Koc, Michal\|Sourkova, Vladimira\|Andera, Ladislav\|Pintzas, Alexander
PMID:	21738740

1145.
Journal:	Clin Chim Acta. 2011 Sep 18;412(19-20):1874-8.
Title:	Differential detection of KRAS mutations in codons 12 and 13 with a modified loop-hybrid (LH) mobility shift assay using an insert-type LH-generator.
Author:	Matsukuma, Shoichi\|Yoshihara, Mitsuyo\|Suda, Tetsuji\|Shiozawa, Manabu\|Akaike, Makoto\|Ishikawa, Tomokazu\|Koizume, Shiro\|Sakuma, Yuji\|Miyagi, Yohei
PMID:	21741959

1146.
Journal:	Oncologist. 2011;16(9):1239-49.
Title:	Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review.
Author:	Baas, Jara M\|Krens, Lisanne L\|Guchelaar, Henk-Jan\|Morreau, Hans\|Gelderblom, Hans
PMID:	21742964

1147.
Journal:	Mod Pathol. 2011 Oct;24(10):1404-12.
Title:	VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
Author:	Vlajnic, Tatjana\|Andreozzi, Maria Carla\|Schneider, Sandra\|Tornillo, Luigi\|Karamitopoulou, Eva\|Lugli, Alessandro\|Ruiz, Christian\|Zlobec, Inti\|Terracciano, Luigi
PMID:	21743435

1148.
Journal:	Expert Rev Mol Diagn. 2011 Jul;11(6):635-42.
Title:	Laboratory methods for KRAS mutation analysis.
Author:	Anderson, Steven M
PMID:	21745016

1149.
Journal:	Cas Lek Cesk. 2011;150(6):321-6.
Title:	[KRAS mutation testing in therapeutic algorithm for treatment of metastatic colorectal carcinoma].
Author:	Dubska, Lenka\|Vyskocilova, Martina\|Nenutil, Rudolf\|Valik, Dalibor\|Knoflickova, Dana\|Fabian, Pavel\|Kocakova, Ilona\|Demlova, Regina\|Beranek, Martin\|Drastikova, Monika\|Vosmikova, Hana\|Boday, Arpad\|Horka, Katerina\|Simova, Jarmila\|Drabek, Jiri\|Ehrmann, Jiri\|Ha
PMID:	21751504

1150.
Journal:	Gan To Kagaku Ryoho. 2011 Jul;38(7):1079-83.
Title:	[Predictive biomarkers of anti-EGFR monoclonal anti-body in colorectal cancer].
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	21772090

1151.
Journal:	Gan To Kagaku Ryoho. 2011 Jul;38(7):1205-8.
Title:	FOLFOX plus cetuximab for a patient with metastatic colorectal cancer with icterus due to multiple liver metastases.
Author:	Mizota, Ayako\|Shitara, Kohei\|Kondo, Chihiro\|Nomura, Motoo\|Yokota, Tomoya\|Takahari, Daisuke\|Ura, Takashi\|Muro, Kei
PMID:	21772113

1152.
Journal:	J Natl Cancer Inst. 2011 Aug 17;103(16):1278.
Title:	Re: Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations.
Author:	Brandi, Giovanni\|Biasco, Guido\|Tavolari, Simona
PMID:	21775746

1153.
Journal:	P T. 2011 May;36(5):263-79.
Title:	Roles of EGFR and KRAS Mutations in the Treatment Of Patients With Non-Small-Cell Lung Cancer.
Author:	Langer, Corey J
PMID:	21785539

1154.
Journal:	Semin Oncol. 2011 Aug;38(4):576-87.
Title:	Predictive molecular classifiers in colorectal cancer.
Author:	Bohanes, Pierre\|LaBonte, Melissa J\|Winder, Thomas\|Lenz, Heinz-Josef
PMID:	21810517

1155.
Journal:	Rinsho Byori. 2011 Jun;59(6):598-601.
Title:	[KRAS mutation test].
Author:	Hinoda, Yuji
PMID:	21815483

1156.
Journal:	Nat Rev Clin Oncol. 2011 Aug 9;8(12):711-9.
Title:	Cancer immunology--analysis of host and tumor factors for personalized medicine.
Author:	Ogino, Shuji\|Galon, Jerome\|Fuchs, Charles S\|Dranoff, Glenn
PMID:	21826083

1157.
Journal:	PLoS One. 2011;6(7):e22769.
Title:	PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.
Author:	Janku, Filip\|Lee, J Jack\|Tsimberidou, Apostolia M\|Hong, David S\|Naing, Aung\|Falchook, Gerald S\|Fu, Siqing\|Luthra, Rajyalakshmi\|Garrido-Laguna, Ignacio\|Kurzrock, Razelle
PMID:	21829508

1158.
Journal:	Am J Surg Pathol. 2011 Sep;35(9):1327-30.
Title:	Does neoadjuvant therapy alter KRAS and/or MSI results in rectal adenocarcinoma testing?
Author:	Ondrejka, Sarah L\|Schaeffer, David F\|Jakubowski, Maureen A\|Owen, David A\|Bronner, Mary P
PMID:	21836482

1159.
Journal:	Fam Cancer. 2011 Dec;10(4):623-31.
Title:	Familial colorectal cancer type X syndrome: two distinct molecular entities?
Author:	Francisco, Ines\|Albuquerque, Cristina\|Lage, Pedro\|Belo, Helio\|Vitoriano, Ines\|Filipe, Bruno\|Claro, Isabel\|Ferreira, Sara\|Rodrigues, Paula\|Chaves, Paula\|Leitao, Carlos Nobre\|Pereira, Antonio Dias
PMID:	21837511

1160.
Journal:	Diagn Cytopathol. 2011 Sep;39(9):703-10.
Title:	Cytology-based gene mutation tests to predict response to anti-epidermal growth factor receptor therapy: a review.
Author:	Malapelle, Umberto\|Bellevicine, Claudio\|Zeppa, Pio\|Palombini, Lucio\|Troncone, Giancarlo
PMID:	21837660

1161.
Journal:	J Natl Cancer Inst. 2011 Oct 19;103(20):1540-51.
Title:	Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803.
Author:	Ng, Kimmie\|Ogino, Shuji\|Meyerhardt, Jeffrey A\|Chan, Jennifer A\|Chan, Andrew T\|Niedzwiecki, Donna\|Hollis, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Benson, Al B 3rd\|Schaefer, Paul L\|Whittom, Renaud\|Hantel, Alexander\|Goldberg, Richard M\|Bertagnolli, Monica M\|V
PMID:	21849660

1162.
Journal:	Clin Transl Oncol. 2011 Sep;13(9):664-71.
Title:	APC and KRAS mutations in distal colorectal polyps are related to smoking habits in men: results of a cross-sectional study.
Author:	Martinez, Fernando\|Fernandez-Martos, Carlos\|Quintana, Maria Jesus\|Castells, Antoni\|Llombart, Antonio\|Iniguez, Francisco\|Guillem, Vicente\|Dasi, Francisco
PMID:	21865138

1163.
Journal:	Ann Surg. 2011 Sep;254(3):486-92; discussion 492-3.
Title:	Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer.
Author:	Garcia-Aguilar, Julio\|Chen, Zhenbin\|Smith, David D\|Li, Wenyan\|Madoff, Robert D\|Cataldo, Peter\|Marcet, Jorge\|Pastor, Carlos
PMID:	21865946

1164.
Journal:	Anticancer Res. 2011 Sep;31(9):2971-4.
Title:	The efficacy of gemcitabine as salvage treatment in patients with refractory advanced colorectal cancer (CRC): a single institution experience.
Author:	Saif, Muhammad Wasif\|Kaley, Kristin\|Penney, Robin\|Hotchkiss, Susan\|Syrigos, Kostas N\|Strimpakos, Alexios S
PMID:	21868546

1165.
Journal:	Anticancer Res. 2011 Jul;31(7):2453-9.
Title:	Oncogenic KRAS regulates miR-200c and miR-221/222 in a 3D-specific manner in colorectal cancer cells.
Author:	Tsunoda, Toshiyuki\|Takashima, Yasuo\|Yoshida, Yasuhiro\|Doi, Keiko\|Tanaka, Yoko\|Fujimoto, Takahiro\|Machida, Takashi\|Ota, Takeharu\|Koyanagi, Midori\|Kuroki, Masahide\|Sasazuki, Takehiko\|Shirasawa, Senji
PMID:	21873159

1166.
Journal:	Anticancer Res. 2011 Jul;31(7):2535-9.
Title:	KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines.
Author:	Yoshida, Yasuhiro\|Tsunoda, Toshiyuki\|Doi, Keiko\|Tanaka, Yoko\|Fujimoto, Takahiro\|Machida, Takashi\|Ota, Takeharu\|Koyanagi, Midori\|Takashima, Yasuo\|Sasazuki, Takehiko\|Kuroki, Masahide\|Iwasaki, Akinori\|Shirasawa, Senji
PMID:	21873171

1167.
Journal:	Curr Oncol. 2011 Aug;18(4):e180-4.
Title:	Canadian Expert Group consensus recommendations: KRAS testing in colorectal cancer.
Author:	Aubin, F\|Gill, S\|Burkes, R\|Colwell, B\|Kamel-Reid, S\|Koski, S\|Pollett, A\|Samson, B\|Tehfe, M\|Wong, R\|Young, S\|Soulieres, D
PMID:	21874108

1168.
Journal:	Clin Cancer Res. 2011 Oct 15;17(20):6522-30.
Title:	EGFR- and VEGF(R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies.
Author:	Poindessous, Virginie\|Ouaret, Djamila\|El Ouadrani, Karima\|Battistella, Aude\|Megalophonos, Virginie F\|Kamsu-Kom, Nyam\|Petitprez, Amelie\|Escargueil, Alexandre E\|Boudou, Pascaline\|Dumont, Sylvie\|Cervera, Pascale\|Flejou, Jean-Francois\|Andre, Thierry\|Tournigan
PMID:	21880790

1169.
Journal:	Histopathology. 2011 Aug;59(2):342-5.
Title:	Multiple intratumoral KRAS mutations can clonally segregate to different lymph node metastases in colon cancer.
Author:	Jahn, Stephan W\|Winter, Gerlinde\|Stacher, Elvira\|Halbwedl, Iris\|Gattenlohner, Stefan\|Stockinger, Richard\|Spreitzer, Stefan\|Waldispuehl-Geigl, Julie\|Geigl, Jochen B\|Offner, Felix\|Hoefler, Gerald
PMID:	21884216

1170.
Journal:	Hum Immunol. 2011 Nov;72(11):1022-8.
Title:	Tumor-infiltrating lymphocytes and dendritic cells in human colorectal cancer: their relationship to KRAS mutational status and disease recurrence.
Author:	Kocian, Petr\|Sedivcova, Monika\|Drgac, Jan\|Cerna, Katerina\|Hoch, Jiri\|Kodet, Roman\|Bartunkova, Jirina\|Spisek, Radek\|Fialova, Anna
PMID:	21884745

1171.
Journal:	Oncology. 2011;81(1):3-8.
Title:	KRAS mutation in metastatic pancreatic ductal adenocarcinoma: results of a multicenter phase II study evaluating efficacy of cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line therapy.
Author:	Kullmann, F\|Hartmann, A\|Stohr, R\|Messmann, H\|Dollinger, M M\|Trojan, J\|Fuchs, M\|Hollerbach, S\|Harder, J\|Troppmann, M\|Kutscheidt, A\|Endlicher, E
PMID:	21894049

1172.
Journal:	J Clin Oncol. 2011 Oct 1;29(28):3783-90.
Title:	Phase I pharmacokinetic and pharmacodynamic dose-escalation study of RG7160 (GA201), the first glycoengineered monoclonal antibody against the epidermal growth factor receptor, in patients with advanced solid tumors.
Author:	Paz-Ares, Luis G\|Gomez-Roca, Carlos\|Delord, Jean-Pierre\|Cervantes, Andres\|Markman, Ben\|Corral, Jesus\|Soria, Jean-Charles\|Berge, Yann\|Roda, Desamparados\|Russell-Yarde, Fiona\|Hollingsworth, Simon\|Baselga, Jose\|Umana, Pablo\|Manenti, Luigi\|Tabernero, Josep
PMID:	21900113

1173.
Journal:	Sci Transl Med. 2011 Sep 7;3(99):99ra86.
Title:	Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.
Author:	Yonesaka, Kimio\|Zejnullahu, Kreshnik\|Okamoto, Isamu\|Satoh, Taroh\|Cappuzzo, Federico\|Souglakos, John\|Ercan, Dalia\|Rogers, Andrew\|Roncalli, Massimo\|Takeda, Masayuki\|Fujisaka, Yasuhito\|Philips, Juliet\|Shimizu, Toshio\|Maenishi, Osamu\|Cho, Yonggon\|Sun, Jason\|D
PMID:	21900593

1174.
Journal:	PLoS One. 2011;6(8):e24114.
Title:	Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.
Author:	Vasovcak, Peter\|Pavlikova, Kristyna\|Sedlacek, Zdenek\|Skapa, Petr\|Kouda, Martin\|Hoch, Jiri\|Krepelova, Anna
PMID:	21901162

1175.
Journal:	PLoS One. 2011;6(9):e24419.
Title:	Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome.
Author:	Danielsen, Stine A\|Cekaite, Lina\|Agesen, Trude H\|Sveen, Anita\|Nesbakken, Arild\|Thiis-Evensen, Espen\|Skotheim, Rolf I\|Lind, Guro E\|Lothe, Ragnhild A
PMID:	21909432

1176.
Journal:	Radiat Oncol. 2011 Sep 12;6:114.
Title:	Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy.
Author:	Davies, Janine M\|Trembath, Dimitri\|Deal, Allison M\|Funkhouser, William K\|Calvo, Benjamin F\|Finnegan, Timothy\|Weck, Karen E\|Tepper, Joel E\|O'Neil, Bert H
PMID:	21910869

1177.
Journal:	Gan To Kagaku Ryoho. 2011 Sep;38(9):1533-6.
Title:	[A case of sigmoid colon cancer with liver and ovarian metastases effectively treated by panitumumab after acquiring resistance to prior chemotherapy regimens].
Author:	Honda, Kuniomi\|Hata, Yoshitaka\|Ihara, Eikichi\|Tomita, Yosuke\|Miyata, Seiichi\|Sumida, Yorinobu\|Ihara, Yuji\|Misawa, Tadashi
PMID:	21918357

1178.
Journal:	Cancer Biol Ther. 2011 Oct 1;12(7):557-68. Epub 2011 Oct 1.
Title:	Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients.
Author:	Kline, Christina Leah\|Sheikh, Hassan S\|Scicchitano, Angelique\|Gingrich, Rebecca\|Beachler, Cheryl\|Finnberg, Niklas K\|Liao, Jason\|Sivik, Jeffrey\|El-Deiry, Wafik S
PMID:	21931273

1179.
Journal:	Toxicol Pathol. 2011 Dec;39(7):1065-74.
Title:	Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors.
Author:	Pandiri, Arun R\|Sills, Robert C\|Hoenerhoff, Mark J\|Peddada, Shyamal D\|Ton, Thai-Vu T\|Hong, Hue-Hua L\|Flake, Gordon P\|Malarkey, David E\|Olson, Greg R\|Pogribny, Igor P\|Walker, Nigel J\|Boudreau, Mary D
PMID:	21937742

1180.
Journal:	Rinsho Byori. 2011 Aug;59(8):757-62.
Title:	[Tm analysis method using a quenching probe is a simple and rapid way to simultaneously detect KRAS and BRAF mutations].
Author:	Akagi, Kiwamu\|Arai, Yoshiko
PMID:	21942085

1181.
Journal:	Mol Cancer. 2011 Sep 23;10:118.
Title:	BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
Author:	Makrodouli, Eleni\|Oikonomou, Eftychia\|Koc, Michal\|Andera, Ladislav\|Sasazuki, Takehiko\|Shirasawa, Senji\|Pintzas, Alexander
PMID:	21943101

1182.
Journal:	BMC Cancer. 2011 Sep 24;11:406.
Title:	Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing.
Author:	Borras, Emma\|Jurado, Ismael\|Hernan, Imma\|Gamundi, Maria Jose\|Dias, Miguel\|Marti, Isabel\|Mane, Begona\|Arcusa, Angels\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	21943394

1183.
Journal:	PLoS One. 2011;6(9):e25062.
Title:	TGFBR2 and BAX mononucleotide tract mutations, microsatellite instability, and prognosis in 1072 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Yamauchi, Mai\|Kuchiba, Aya\|Imamura, Yu\|Liao, Xiaoyun\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21949851

1184.
Journal:	Genet Mol Res. 2011 Oct 3;10(4):3002-12.
Title:	Prospective analysis of KRAS wild-type patients with metastatic colorectal cancer using cetuximab plus FOLFIRI or FOLFOX4 treatment regimens.
Author:	Huang, M Y\|Chen, M J\|Tsai, H L\|Kuo, C H\|Ma, C J\|Hou, M F\|Chuang, S C\|Lin, S R\|Wang, J Y
PMID:	21968808

1185.
Journal:	Clin Transl Oncol. 2011 Oct;13(10):721-7.
Title:	Multidisciplinary approach of colorectal liver metastases.
Author:	Juez, I\|Rubio, C\|Figueras, J
PMID:	21975333

1186.
Journal:	J Clin Invest. 2011 Nov;121(11):4311-21.
Title:	Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.
Author:	Ebi, Hiromichi\|Corcoran, Ryan B\|Singh, Anurag\|Chen, Zhao\|Song, Youngchul\|Lifshits, Eugene\|Ryan, David P\|Meyerhardt, Jeffrey A\|Benes, Cyril\|Settleman, Jeffrey\|Wong, Kwok-Kin\|Cantley, Lewis C\|Engelman, Jeffrey A
PMID:	21985784

1187.
Journal:	Clin Cancer Res. 2011 Dec 15;17(24):7723-31.
Title:	A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.
Author:	Smits, Kim M\|Paranjape, Trupti\|Nallur, Sunitha\|Wouters, Kim A D\|Weijenberg, Matty P\|Schouten, Leo J\|van den Brandt, Piet A\|Bosman, Fred T\|Weidhaas, Joanne B\|van Engeland, Manon
PMID:	21994416

1188.
Journal:	Expert Rev Anticancer Ther. 2011 Oct;11(10):1499-503.
Title:	Anti-EGFR therapy in first-line colorectal cancer.
Author:	Lamas, Maria J\|Duran, Goretti\|Gallardo, Elena
PMID:	21999123

1189.
Journal:	Genome Biol. 2011 Oct 19;12(10):R103.
Title:	Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.
Author:	Kloosterman, Wigard P\|Hoogstraat, Marlous\|Paling, Oscar\|Tavakoli-Yaraki, Masoumeh\|Renkens, Ivo\|Vermaat, Joost S\|van Roosmalen, Markus J\|van Lieshout, Stef\|Nijman, Isaac J\|Roessingh, Wijnand\|van 't Slot, Ruben\|van de Belt, Jose\|Guryev, Victor\|Koudijs, Marc
PMID:	22014273

1190.
Journal:	Virchows Arch. 2011 Nov;459(5):487-93.
Title:	Molecular morphometric analysis shows relative intra-tumoural homogeneity for KRAS mutations in colorectal cancer.
Author:	Farber, Liora\|Efrati, Edna\|Elkin, Hela\|Peerless, Yehudit\|Sabo, Edmond\|Ben-Izhak, Ofer\|Hershkovitz, Dov
PMID:	22016105

1191.
Journal:	Expert Rev Mol Diagn. 2011 Nov;11(8):799-802.
Title:	Detection of KRAS and BRAF mutations in advanced colorectal cancer by allele-specific single-base primer extension.
Author:	Balschun, Katharina\|Wenke, Ann-Kathrin\|Rocken, Christoph\|Haag, Jochen
PMID:	22022941

1192.
Journal:	Neoplasia. 2011 Oct;13(10):931-46.
Title:	Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death.
Author:	Berdiel-Acer, Mireia\|Bohem, Monika E\|Lopez-Doriga, Adriana\|Vidal, August\|Salazar, Ramon\|Martinez-Iniesta, Maria\|Santos, Cristina\|Sanjuan, Xavier\|Villanueva, Alberto\|Mollevi, David G
PMID:	22028619

1193.
Journal:	J Natl Compr Canc Netw. 2011 Nov;9(11):1293-302.
Title:	Biomarker use in colorectal cancer therapy.
Author:	Kelley, Robin K\|Wang, Grace\|Venook, Alan P
PMID:	22056657

1194.
Journal:	Pathol Res Pract. 2011 Dec 15;207(12):762-8.
Title:	Frequency of KRAS, BRAF, and PIK3CA mutations in advanced colorectal cancers: Comparison of peptide nucleic acid-mediated PCR clamping and direct sequencing in formalin-fixed, paraffin-embedded tissue.
Author:	Kwon, Mi Jung\|Lee, Seung Eun\|Kang, So Young\|Choi, Yoon-La
PMID:	22070922

1195.
Journal:	Diagn Mol Pathol. 2011 Dec;20(4):189-93.
Title:	KRAS detection in colonic tumors by DNA extraction from FTA paper: the molecular touch-prep.
Author:	Petras, Melissa L\|Lefferts, Joel A\|Ward, Brian P\|Suriawinata, Arief A\|Tsongalis, Gregory J
PMID:	22089345

1196.
Journal:	Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):562-8.
Title:	Expression of p16INK4a, alone or combined with p53, is predictive of better prognosis in colorectal adenocarcinoma in Tunisian patients.
Author:	Miladi-Abdennadher, Imen\|Abdelmaksoud-Damak, Rania\|Ayadi, Lobna\|Khabir, Abdelmajid\|Amouri, Ali\|Frikha, Foued\|Ellouz, Sameh\|Frikha, Mounir\|Sellami-Boudawara, Tahia\|Mokdad-Gargouri, Raja
PMID:	22095233

1197.
Journal:	BMC Cancer. 2011 Nov 25;11:496.
Title:	Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.
Author:	Dahan, Laetitia\|Norguet, Emmanuelle\|Etienne-Grimaldi, Marie-Christine\|Formento, Jean-Louis\|Gasmi, Mohamed\|Nanni, Isabelle\|Gaudart, Jean\|Garcia, Stephane\|Ouafik, L'Houcine\|Seitz, Jean-Francois\|Milano, Gerard
PMID:	22117530

1198.
Journal:	Int J Biol Markers. 2011 Oct-Dec;26(4):276-7.
Title:	KRAS and BRAF mutation status in patients with sporadic colorectal cancer: data from two different Mediterranean countries.
Author:	Symvoulakis, Emmanouil K\|Zaravinos, Apostolos\|Zoras, Odysseas\|Spandidos, Demetrios A
PMID:	22139644

1199.
Journal:	Cesk Patol. 2011 Oct;47(4):154-8.
Title:	[Molecular predictive markers of EGFR-targeted therapy in metastatic colorectal cancer].
Author:	Fabian, P\|Berkovcova, J
PMID:	22145213

1200.
Journal:	World J Gastroenterol. 2011 Nov 21;17(43):4779-86.
Title:	Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer.
Author:	Guo, Gui-Fang\|Jiang, Wen-Qi\|Zhang, Bei\|Cai, Yu-Chen\|Xu, Rui-Hua\|Chen, Xu-Xian\|Wang, Fang\|Xia, Liang-Ping
PMID:	22147978

1201.
Journal:	World J Gastroenterol. 2011 Nov 14;17(42):4729-33.
Title:	Neuroendocrine and squamous colonic composite carcinoma: case report with molecular analysis.
Author:	Wentz, Sabrina C\|Vnencak-Jones, Cindy\|Chopp, William V
PMID:	22180717

1202.
Journal:	Int J Mol Epidemiol Genet. 2011;2(4):300-15. Epub 2011 Dec 3.
Title:	Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer.
Author:	Poole, Elizabeth M\|Curtin, Karen\|Hsu, Li\|Kulmacz, Richard J\|Duggan, David J\|Makar, Karen W\|Xiao, Liren\|Carlson, Christopher S\|Slattery, Martha L\|Caan, Bette J\|Potter, John D\|Ulrich, Cornelia M
PMID:	22199994

1203.
Journal:	PLoS One. 2011;6(12):e29146.
Title:	KRAS mutations testing in colorectal carcinoma patients in Italy: from guidelines to external quality assessment.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Bardelli, Alberto\|Gambacorta, Marcello\|Botti, Gerardo\|Nappi, Oscar\|Siena, Salvatore\|Ciardiello, Fortunato\|Taddei, Gianluigi\|Marchetti, Antonio
PMID:	22216189

1204.
Journal:	Oncology. 2011;81(5-6):359-64.
Title:	Clinical and economic aspects of KRAS mutational status as predictor for epidermal growth factor receptor inhibitor therapy in metastatic colorectal cancer patients.
Author:	Konigsberg, Robert\|Hulla, Wolfgang\|Klimpfinger, Martin\|Reiner-Concin, Angelika\|Steininger, Tanja\|Buchler, Wilfried\|Terkola, Robert\|Dittrich, Christian
PMID:	22248908

1205.
Journal:	Folia Histochem Cytobiol. 2011;49(4):570-8.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Rojo, Marcial Garcia
PMID:	22252751

1206.
Journal:	Folia Histochem Cytobiol. 2011;49(4):729-33.
Title:	Concurrent mutation in exons 1 and 2 of the K-ras oncogene in colorectal cancer.
Author:	Palmirotta, Raffaele\|Savonarola, Annalisa\|Ludovici, Giorgia\|De Marchis, Maria Laura\|Covello, Renato\|Ettorre, Giuseppe Maria\|Ialongo, Cristiano\|Guadagni, Fiorella
PMID:	22252770

1207.
Journal:	Klin Onkol. 2011;24(6):465-9.
Title:	[The role of chemotherapy and targeted antiVEGF- and antiEGFR-therapy in metastatic colorectal cancer: a case report of long-term and intensive response].
Author:	Nemecek, R\|Vyzula, R
PMID:	22257237

1208.
Journal:	Lijec Vjesn. 2011 Nov-Dec;133(11-12):403-7.
Title:	[The role of KRAS gene mutation testing in colorectal cancer--a predictive biomarker of response to EGFR inhibitors therapy].
Author:	Rako, Ivana\|Jakic-Razumovic, Jasminka\|Caban, Domagoj\|Sertic, Jadranka\|Katalinic, Darko\|Golem, Hilda\|Plestina, Stjepko
PMID:	22329297

1209.
Journal:	Cancer Discov. 2011 Nov;1(6):508-23.
Title:	A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Author:	Bertotti, Andrea\|Migliardi, Giorgia\|Galimi, Francesco\|Sassi, Francesco\|Torti, Davide\|Isella, Claudio\|Cora, Davide\|Di Nicolantonio, Federica\|Buscarino, Michela\|Petti, Consalvo\|Ribero, Dario\|Russolillo, Nadia\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alber
PMID:	22586653

1210.
Journal:	Exp Ther Med. 2011 Jul;2(4):695-700.
Title:	Sessile serrated adenoma shares similar genetic and epigenetic features with microsatellite unstable colon cancer in a location-dependent manner.
Author:	Maeda, Takafumi\|Suzuki, Koichi\|Togashi, Kazutomo\|Nokubi, Mitsuhiro\|Saito, Masaaki\|Tsujinaka, Shingo\|Kamiyama, Hidenori\|Konishi, Fumio
PMID:	22977561

1211.
Journal:	Chin J Cancer Res. 2011 Dec;23(4):271-5.
Title:	Wild-Type KRAS and BRAF Could Predict Response to Cetuximab in Chinese Colorectal Cancer Patients.
Author:	Gao, Jing\|Wang, Ting-Ting\|Yu, Jing-Wei\|Li, Yan-Yan\|Shen, Lin
PMID:	23357879

1212.
Journal:	Cancers (Basel). 2011 Mar 29;3(2):1622-38.
Title:	Predictive and prognostic factors in colorectal cancer: a personalized approach.
Author:	Kulendran, Myutan\|Stebbing, John F\|Marks, Christopher G\|Rockall, Timothy A
PMID:	24212777

1213.
Journal:	Cancers (Basel). 2011 Apr 1;3(2):1844-60.
Title:	Biomarkers in advanced colorectal cancer: challenges in translating clinical research into practice.
Author:	Lemech, Charlotte\|Arkenau, Hendrik-Tobias
PMID:	24212785

1214.
Journal:	Cancers (Basel). 2011 Jun 23;3(2):2767-810.
Title:	Review of histopathological and molecular prognostic features in colorectal cancer.
Author:	Marzouk, Ola\|Schofield, John
PMID:	24212832

1215.
Journal:	Gastroenterol Hepatol Bed Bench. 2011 Spring;4(2):70-5.
Title:	The role of kras mutations and MSI status in diagnosis of colorectal cancer.
Author:	Shemirani, Atena Irani\|Haghighi, Mahdi Montazer\|Milanizadeh, Saman\|Taleghani, Mohammad Yaghoob\|Fatemi, Seyed Reza\|Damavand, Behzad\|Akbari, Zahra\|Zali, Mohammad Reza
PMID:	24834160

1216.
Journal:	Gastroenterology Res. 2011 Aug;4(4):162-167.
Title:	Biotherapy in the Adjuvant Treatment of Colorectal Cancer.
Author:	Tazi, El Mehdi\|Essadi, Ismail\|Boutayeb, Saber\|M'rabti, Hind\|Errihani, Hassan
PMID:	27942334

1217.
Journal:	Colorectal Dis. 2012 Jan;14(1):3-17.
Title:	Review of biomarkers in colorectal cancer.
Author:	Newton, K F\|Newman, W\|Hill, J
PMID:	21040359

1218.
Journal:	Int J Cancer. 2012 Feb 1;130(3):653-64.
Title:	Genetic variation in bone morphogenetic protein and colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Herrick, Jennifer S\|Kadlubar, Susan\|Caan, Bette J\|Potter, John D\|Wolff, Roger K
PMID:	21387313

1219.
Journal:	Int J Cancer. 2012 Feb 15;130(4):837-46.
Title:	Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Author:	Middeldorp, A\|van Eijk, R\|Oosting, J\|Forte, G I\|van Puijenbroek, M\|van Nieuwenhuizen, M\|Corver, W E\|Ruano, D\|Caldes, T\|Wijnen, J\|Morreau, H\|van Wezel, T
PMID:	21445971

1220.
Journal:	Cancer Treat Rev. 2012 Feb;38(1):63-7.
Title:	Critical comments for roles of biomarkers in the diagnosis and treatment of cancer.
Author:	Saijo, Nagahiro
PMID:	21652149

1221.
Journal:	Genome Res. 2012 Feb;22(2):271-82.
Title:	Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Author:	Hinoue, Toshinori\|Weisenberger, Daniel J\|Lange, Christopher P E\|Shen, Hui\|Byun, Hyang-Min\|Van Den Berg, David\|Malik, Simeen\|Pan, Fei\|Noushmehr, Houtan\|van Dijk, Cornelis M\|Tollenaar, Rob A E M\|Laird, Peter W
PMID:	21659424

1222.
Journal:	Invest New Drugs. 2012 Aug;30(4):1607-13.
Title:	Biweekly cetuximab plus irinotecan as second-line chemotherapy for patients with irinotecan-refractory and KRAS wild-type metastatic colorectal cancer according to epidermal growth factor receptor expression status.
Author:	Kang, Myoung Joo\|Hong, Yong Sang\|Kim, Kyu-pyo\|Kim, Sun Young\|Baek, Ji Yeon\|Ryu, Min-Hee\|Lee, Jae-Lyun\|Chang, Heung Moon\|Kim, Mi-Jung\|Chang, Hee Jin\|Kang, Yoon-Koo\|Kim, Tae Won
PMID:	21706149

1223.
Journal:	Appl Immunohistochem Mol Morphol. 2012 Mar;20(2):146-52.
Title:	Relationship between expression of ras p21 oncoprotein and mutation status of the K-ras gene in sporadic colorectal cancer patients in Tunisia.
Author:	Sammoud, Souraya\|Khiari, Meriem\|Semeh, Amara\|Amine, Lounis\|Ines, Chaar\|Amira, Arfaoui\|Lilia, Kriaa\|Taher, Khalfallah\|Sabeh, Mzabi\|Saadia, Bouraoui
PMID:	21768877

1224.
Journal:	Int J Surg Pathol. 2012 Apr;20(2):185-90.
Title:	Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Author:	Remo, Andrea\|Zanella, Caterina\|Molinari, Enrico\|Talamini, Alberto\|Tollini, Filippo\|Piacentini, Paolo\|Battaglia, Paolo\|Baritono, Elisabetta\|Bonetti, Andrea\|Lanza, Franco\|Fasolin, Antonio\|Manfrin, Erminia\|Vendraminelli, Roberto
PMID:	21791485

1225.
Journal:	Inflamm Bowel Dis. 2012 Apr;18(4):641-8.
Title:	Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers.
Author:	Olaru, Alexandru V\|Cheng, Yulan\|Agarwal, Rachana\|Yang, Jian\|David, Stefan\|Abraham, John M\|Yu, Wayne\|Kwon, John H\|Lazarev, Mark\|Brant, Steven R\|Marohn, Michael R\|Hutcheon, David F\|Harpaz, Noam\|Meltzer, Stephen J\|Mori, Yuriko
PMID:	21830278

1226.
Journal:	Int J Oncol. 2012 Jan;40(1):176-84.
Title:	The effect of a dimeric Affibody molecule (ZEGFR:1907)2 targeting EGFR in combination with radiation in colon cancer cell lines.
Author:	Haggblad Sahlberg, Sara\|Spiegelberg, Diana\|Lennartsson, Johan\|Nygren, Peter\|Glimelius, Bengt\|Stenerlow, Bo
PMID:	21879255

1227.
Journal:	Cancer Chemother Pharmacol. 2012 Mar;69(3):577-90.
Title:	Pharmacodynamics of DT-IgG, a dual-targeting antibody against VEGF-EGFR, in tumor xenografted mice.
Author:	Hurwitz, Selwyn J\|Zhang, Hongzheng\|Yun, Sujin\|Batuwangala, Thil D\|Steward, Michael\|Holmes, Steve D\|Rycroft, Daniel\|Pan, Lin\|Tighiouart, Mourad\|Shin, Hyung Ju C\|Koenig, Lydia\|Wang, Yuxiang\|Chen, Zhuo Georgia\|Shin, Dong M
PMID:	21913035

1228.
Journal:	Genes Chromosomes Cancer. 2012 Jan;51(1):1-9.
Title:	MicroRNA profiling differentiates colorectal cancer according to KRAS status.
Author:	Mosakhani, Neda\|Sarhadi, Virinder Kaur\|Borze, Ioana\|Karjalainen-Lindsberg, Marja-Liisa\|Sundstrom, Jari\|Ristamaki, Raija\|Osterlund, Pia\|Knuutila, Sakari
PMID:	21922590

1229.
Journal:	Clin Colorectal Cancer. 2012 Mar;11(1):14-23.
Title:	Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma.
Author:	Peeters, Marc\|Cohn, Allen\|Kohne, Claus-Henning\|Douillard, Jean-Yves
PMID:	21925954

1230.
Journal:	Int J Cancer. 2012 Aug 15;131(4):813-20.
Title:	Oncogenic PIK3CA mutations in colorectal cancers and polyps.
Author:	Whitehall, Vicki L J\|Rickman, Celestine\|Bond, Catherine E\|Ramsnes, Ingunn\|Greco, Sonia A\|Umapathy, Aarti\|McKeone, Diane\|Faleiro, Rebecca J\|Buttenshaw, Ron L\|Worthley, Daniel L\|Nayler, Sam\|Zhao, Zhen Zhen\|Montgomery, Grant W\|Mallitt, Kylie-Ann\|Jass, Jeremy
PMID:	21932420

1231.
Journal:	Int J Oncol. 2012 Feb;40(2):378-84.
Title:	Detection of KRAS mutations in colorectal cancer with Fast COLD-PCR.
Author:	Carotenuto, Pietro\|Roma, Cristin\|Cozzolino, Salvatore\|Fenizia, Francesca\|Rachiglio, Anna Maria\|Tatangelo, Fabiana\|Iannaccone, Alessia\|Baron, Luigi\|Botti, Gerardo\|Normanno, Nicola
PMID:	21971641

1232.
Journal:	J Pathol. 2012 Feb;226(3):544-55.
Title:	Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer.
Author:	Han, Hai-Bo\|Gu, Jin\|Zuo, Hui-Jing\|Chen, Zhi-Guo\|Zhao, Wei\|Li, Ming\|Ji, Deng-Bo\|Lu, You-Yong\|Zhang, Zhi-Qian
PMID:	21984339

1233.
Journal:	Surgery. 2012 Apr;151(4):564-70.
Title:	CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer.
Author:	Jo, Peter\|Jung, Klaus\|Grade, Marian\|Conradi, Lena-Christin\|Wolff, Hendrik A\|Kitz, Julia\|Becker, Heinz\|Ruschoff, Josef\|Hartmann, Arndt\|Beissbarth, Tim\|Muller-Dornieden, Annegret\|Ghadimi, Michael\|Schneider-Stock, Regine\|Gaedcke, Jochen
PMID:	22001634

1234.
Journal:	Mol Carcinog. 2012 Dec;51(12):1003-8.
Title:	Assessment of three epigenotypes in colorectal cancer by combined bisulfite restriction analysis.
Author:	Karpinski, Pawel\|Szmida, Elzbieta\|Misiak, Blazej\|Ramsey, David\|Leszczynski, Przemyslaw\|Bebenek, Marek\|Sedziak, Tomasz\|Grzebieniak, Zygmunt\|Jonkisz, Anna\|Lebioda, Arleta\|Sasiadek, Maria M
PMID:	22006538

1235.
Journal:	Clin Gastroenterol Hepatol. 2012 Mar;10(3):272-7.e1.
Title:	The stool DNA test is more accurate than the plasma septin 9 test in detecting colorectal neoplasia.
Author:	Ahlquist, David A\|Taylor, William R\|Mahoney, Douglas W\|Zou, Hongzhi\|Domanico, Michael\|Thibodeau, Stephen N\|Boardman, Lisa A\|Berger, Barry M\|Lidgard, Graham P
PMID:	22019796

1236.
Journal:	Exp Cell Res. 2012 Jan 15;318(2):160-8.
Title:	Novel approach to abuse the hyperactive K-Ras pathway for adenoviral gene therapy of colorectal cancer.
Author:	Naumov, Inna\|Kazanov, Dina\|Lisiansky, Victoria\|Starr, Alex\|Aroch, Ilan\|Shapira, Shiran\|Kraus, Sarah\|Arber, Nadir
PMID:	22020090

1237.
Journal:	Int J Cancer. 2012 Sep 1;131(5):1169-78.
Title:	Tumor TP53 expression status, body mass index and prognosis in colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Liao, Xiaoyun\|Imamura, Yu\|Yamauchi, Mai\|Qian, Zhi Rong\|Nishihara, Reiko\|Sato, Kaori\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22038927

1238.
Journal:	Ann Oncol. 2012 Jun;23(6):1518-25.
Title:	PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis.
Author:	Mao, C\|Yang, Z Y\|Hu, X F\|Chen, Q\|Tang, J L
PMID:	22039088

1239.
Journal:	Anticancer Agents Med Chem. 2012 Feb;12(2):163-71.
Title:	Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers?
Author:	Yokota, Tomoya
PMID:	22043994

1240.
Journal:	Cancer Cytopathol. 2012 Jun 25;120(3):145-60.
Title:	Role of ancillary studies in fine-needle aspiration from selected tumors.
Author:	Schmitt, Fernando\|Barroca, Helena
PMID:	22045615

1241.
Journal:	Cell Biochem Biophys. 2012 Apr;62(3):415-20.
Title:	Comparative screening of K-ras mutations in colorectal cancer and lung cancer patients using a novel real-time PCR with ADx-K-ras kit and Sanger DNA sequencing.
Author:	Zhang, Haiping\|Zheng, Xiongwei\|Ji, Tianhai\|Fu, Li\|Bai, Dongyu\|Liao, Yongqiang\|Zhang, Haifang\|Ding, Yi\|Zheng, Limou
PMID:	22048888

1242.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):101-11.
Title:	Phase III trial of cetuximab, bevacizumab, and 5-fluorouracil/leucovorin vs. FOLFOX-bevacizumab in colorectal cancer.
Author:	Saltz, Leonard\|Badarinath, Suprith\|Dakhil, Shaker\|Bienvenu, Bryan\|Harker, W Graydon\|Birchfield, George\|Tokaz, Laurence K\|Barrera, David\|Conkling, Paul R\|O'Rourke, Mark A\|Richards, Donald A\|Reidy, Diane\|Solit, David\|Vakiani, Efsevia\|Capanu, Marinella\|Scale
PMID:	22055112

1243.
Journal:	Gastroenterology. 2012 Feb;142(2):248-56; quiz e25-6.
Title:	Next-generation stool DNA test accurately detects colorectal cancer and large adenomas.
Author:	Ahlquist, David A\|Zou, Hongzhi\|Domanico, Michael\|Mahoney, Douglas W\|Yab, Tracy C\|Taylor, William R\|Butz, Malinda L\|Thibodeau, Stephen N\|Rabeneck, Linda\|Paszat, Lawrence F\|Kinzler, Kenneth W\|Vogelstein, Bert\|Bjerregaard, Niels Chr\|Laurberg, Soren\|Sorensen,
PMID:	22062357

1244.
Journal:	J Gastroenterol. 2012 Mar;47(3):266-75.
Title:	Preclinical study of the DNA repair inhibitor Dbait in combination with chemotherapy in colorectal cancer.
Author:	Devun, Flavien\|Bousquet, Guilhem\|Biau, Julian\|Herbette, Aurelie\|Roulin, Christophe\|Berger, Frederique\|Sun, Jian-Sheng\|Robine, Sylvie\|Dutreix, Marie
PMID:	22068457

1245.
Journal:	Int J Oncol. 2012 Mar;40(3):782-8.
Title:	Two initiation sites of early detection of colon cancer, revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of tumor cells.
Author:	Amsterdam, Abraham\|Shezen, Elias\|Raanan, Calanit\|Schreiber, Letizia\|Slilat, Yasmin\|Fabrikant, Yakov\|Melzer, Ehud\|Seger, Rony
PMID:	22108866

1246.
Journal:	Ann Oncol. 2012 Jul;23(7):1706-12.
Title:	Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Scartozzi, M\|Giampieri, R\|Maccaroni, E\|Mandolesi, A\|Giustini, L\|Silva, R\|Zaniboni, A\|Biscotti, T\|Biagetti, S\|Galizia, E\|Loupakis, F\|Falcone, A\|Bearzi, I\|Cascinu, S
PMID:	22112971

1247.
Journal:	Clin Cancer Res. 2012 Jan 15;18(2):350-9.
Title:	Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution.
Author:	Sylvester, Brooke E\|Huo, Dezheng\|Khramtsov, Andrey\|Zhang, Jing\|Smalling, Rana V\|Olugbile, Sope\|Polite, Blase N\|Olopade, Olufunmilayo I
PMID:	22114137

1248.
Journal:	Am J Pathol. 2012 Feb;180(2):616-25.
Title:	Intermediate methylation epigenotype and its correlation to KRAS mutation in conventional colorectal adenoma.
Author:	Yagi, Koichi\|Takahashi, Hirokazu\|Akagi, Kiwamu\|Matsusaka, Keisuke\|Seto, Yasuyuki\|Aburatani, Hiroyuki\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	22115708

1249.
Journal:	Cancer Treat Rev. 2012 Oct;38(6):618-25.
Title:	Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis.
Author:	Vale, Claire L\|Tierney, Jayne F\|Fisher, David\|Adams, Richard A\|Kaplan, Richard\|Maughan, Timothy S\|Parmar, Mahesh K B\|Meade, Angela M
PMID:	22118887

1250.
Journal:	Clin Exp Metastasis. 2012 Feb;29(2):123-32.
Title:	Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease.
Author:	Vickers, Michael M\|Bar, Jair\|Gorn-Hondermann, Ivan\|Yarom, Nirit\|Daneshmand, Manijeh\|Hanson, Jennifer E L\|Addison, Christina L\|Asmis, Timothy R\|Jonker, Derek J\|Maroun, Jean\|Lorimer, Ian A J\|Goss, Glenwood D\|Dimitroulakos, Jim
PMID:	22120473

1251.
Journal:	Cancer Sci. 2012 Mar;103(3):600-5.
Title:	Predicting cetuximab accumulation in KRAS wild-type and KRAS mutant colorectal cancer using 64Cu-labeled cetuximab positron emission tomography.
Author:	Achmad, Arifudin\|Hanaoka, Hirofumi\|Yoshioka, Hiroki\|Yamamoto, Shinji\|Tominaga, Hideyuki\|Araki, Takuya\|Ohshima, Yasuhiro\|Oriuchi, Noboru\|Endo, Keigo
PMID:	22126621

1252.
Journal:	J Clin Pathol. 2012 Mar;65(3):218-23.
Title:	Standardisation of EGFR FISH in colorectal cancer: results of an international interlaboratory reproducibility ring study.
Author:	Sartore-Bianchi, Andrea\|Fieuws, Steffen\|Veronese, Silvio\|Moroni, Mauro\|Personeni, Nicola\|Frattini, Milo\|Torri, Valter\|Cappuzzo, Federico\|Vander Borght, Sara\|Martin, Vittoria\|Skokan, Margaret\|Santoro, Armando\|Gambacorta, Marcello\|Tejpar, Sabine\|Varella-Gar
PMID:	22130903

1253.
Journal:	Cancer Lett. 2012 Feb 28;315(2):122-8.
Title:	Carnosine inhibits KRAS-mediated HCT116 proliferation by affecting ATP and ROS production.
Author:	Iovine, Barbara\|Iannella, Maria Luigia\|Nocella, Francesca\|Pricolo, Maria Rosaria\|Bevilacqua, Maria Assunta
PMID:	22137144

1254.
Journal:	Dig Dis Sci. 2012 Apr;57(4):913-7.
Title:	Is KRAS mutation associated with interval colorectal cancers?
Author:	Shaukat, Aasma\|Arain, Mustafa\|Anway, Ruth\|Manaktala, Sharad\|Pohlman, Laurie\|Thyagarajan, Bharat
PMID:	22138963

1255.
Journal:	Eur J Cancer. 2012 Feb;48(3):396-406.
Title:	The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Author:	Hernlund, Emma\|Olofsson, Maria Hagg\|Fayad, Walid\|Fryknas, Marten\|Lesiak-Mieczkowska, Karolina\|Zhang, Xiaonan\|Brnjic, Slavica\|Schmidt, Vivien\|D'Arcy, Padraig\|Sjoblom, Tobias\|De Milito, Angelo\|Larsson, Rolf\|Linder, Stig
PMID:	22154651

1256.
Journal:	Mol Biol Rep. 2012 May;39(5):5387-91.
Title:	No evidence for PML-RARa bcr1 fusion gene in colorectal cancer.
Author:	Herreros-Villanueva, Marta
PMID:	22167334

1257.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):85-7.
Title:	To give or not to give anti-epidermal growth factor receptor (EGFR) monoclonal antibodies to patients with KRAS G13D mutation in advanced colorectal cancer.
Author:	Kim, Richard\|Kubal, Timothy
PMID:	22169039

1258.
Journal:	Mol Cancer Ther. 2012 Mar;11(3):720-9.
Title:	Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212.
Author:	Jing, Junping\|Greshock, Joel\|Holbrook, Joanna Dawn\|Gilmartin, Aidan\|Zhang, Xiping\|McNeil, Elizabeth\|Conway, Theresa\|Moy, Christopher\|Laquerre, Sylvie\|Bachman, Kurt\|Wooster, Richard\|Degenhardt, Yan
PMID:	22169769

1259.
Journal:	Virchows Arch. 2012 Feb;460(2):141-9.
Title:	Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma.
Author:	Lee, Sung\|Brophy, Victoria H\|Cao, Jianli\|Velez, Margot\|Hoeppner, Corey\|Soviero, Stephen\|Lawrence, H Jeffrey
PMID:	22173329

1260.
Journal:	Clin Cancer Res. 2012 Feb 15;18(4):1051-62.
Title:	Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models.
Author:	Morelli, M Pia\|Tentler, John J\|Kulikowski, Gillian N\|Tan, Aik-Choon\|Bradshaw-Pierce, Erica L\|Pitts, Todd M\|Brown, Amy M\|Nallapareddy, Sujatha\|Arcaroli, John J\|Serkova, Natalie J\|Hidalgo, Manuel\|Ciardiello, Fortunato\|Eckhardt, S Gail
PMID:	22173548

1261.
Journal:	Clin Cancer Res. 2012 Feb 1;18(3):688-99.
Title:	Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment.
Author:	Vermaat, Joost S\|Nijman, Isaac J\|Koudijs, Marco J\|Gerritse, Frank L\|Scherer, Stefan J\|Mokry, Michal\|Roessingh, Wijnand M\|Lansu, Nico\|de Bruijn, Ewart\|van Hillegersberg, Richard\|van Diest, Paul J\|Cuppen, Edwin\|Voest, Emile E
PMID:	22173549

1262.
Journal:	Mol Cancer Ther. 2012 Mar;11(3):700-9.
Title:	TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity in multiple dosing regimens.
Author:	Hikichi, Yuichi\|Honda, Kohei\|Hikami, Kouki\|Miyashita, Hitoshi\|Kaieda, Isao\|Murai, Saomi\|Uchiyama, Noriko\|Hasegawa, Maki\|Kawamoto, Tomohiro\|Sato, Takashi\|Ichikawa, Takashi\|Cao, Sheldon\|Nie, Zhe\|Zhang, Lilly\|Yang, Johnny\|Kuida, Keisuke\|Kupperman, Erik
PMID:	22188812

1263.
Journal:	Mol Oncol. 2012 Feb;6(1):15-26.
Title:	Drug development to overcome resistance to EGFR inhibitors in lung and colorectal cancer.
Author:	Dienstmann, Rodrigo\|De Dosso, Sara\|Felip, Enriqueta\|Tabernero, Josep
PMID:	22189054

1264.
Journal:	Ann Surg Oncol. 2012 Jun;19(6):1944-53.
Title:	Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer.
Author:	Morikawa, Teppei\|Kuchiba, Aya\|Qian, Zhi Rong\|Mino-Kenudson, Mari\|Hornick, Jason L\|Yamauchi, Mai\|Imamura, Yu\|Liao, Xiaoyun\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22189472

1265.
Journal:	Cell Cycle. 2012 Jan 15;11(2):361-6.
Title:	KRAS alleles: the LCS6 3'UTR variant and KRAS coding sequence mutations in the NCI-60 panel.
Author:	Kundu, Samrat T\|Nallur, Sunitha\|Paranjape, Trupti\|Boeke, Marta\|Weidhaas, Joanne B\|Slack, Frank J
PMID:	22189714

1266.
Journal:	Clin Chem. 2012 Mar;58(3):580-9.
Title:	COLD-PCR enrichment of rare cancer mutations prior to targeted amplicon resequencing.
Author:	Milbury, Coren A\|Correll, Mick\|Quackenbush, John\|Rubio, Renee\|Makrigiorgos, G Mike
PMID:	22194627

1267.
Journal:	Dig Dis Sci. 2012 May;57(5):1271-80.
Title:	The complex intratumoral heterogeneity of colon cancer highlighted by laser microdissection.
Author:	Buob, David\|Fauvel, Harold\|Buisine, Marie-Pierre\|Truant, Stephanie\|Mariette, Christophe\|Porchet, Nicole\|Wacrenier, Agnes\|Copin, Marie-Christine\|Leteurtre, Emmanuelle
PMID:	22198706

1268.
Journal:	Arch Pathol Lab Med. 2012 Jan;136(1):26-32.
Title:	Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma.
Author:	Kamel-Reid, Suzanne\|Zhang, Tong\|Persons, Diane L\|Nikiforova, Marina N\|Halling, Kevin C
PMID:	22208484

1269.
Journal:	Oncologist. 2012;17(1):13.
Title:	Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Author:	Chiorean, E Gabriela\|Ramasubbaiah, Rashmi\|Yu, Menggang\|Picus, Joel\|Bufill, Jose A\|Tong, Yan\|Coleman, Nicki\|Johnston, Erica L\|Currie, Colleen\|Loehrer, Patrick J
PMID:	22210086

1270.
Journal:	Oncologist. 2012;17(1):14.
Title:	Panitumumab in patients with KRAS wild-type colorectal cancer after progression on cetuximab.
Author:	Wadlow, Raymond C\|Hezel, Aram F\|Abrams, Thomas A\|Blaszkowsky, Lawrence S\|Fuchs, Charles S\|Kulke, Matthew H\|Kwak, Eunice L\|Meyerhardt, Jeffrey A\|Ryan, David P\|Szymonifka, Jackie\|Wolpin, Brian M\|Zhu, Andrew X\|Clark, Jeffrey W
PMID:	22210091

1271.
Journal:	Environ Mol Mutagen. 2012 Jan;53(1):22-31.
Title:	Differences in the frequencies of K-ras c12-13 genotypes by gender and pathologic phenotypes in colorectal tumors measured using the allele discrimination method.
Author:	Chow, Lihui\|Lin, Peng-Chan\|Chang, Jeffrey S\|Chu, Pei-Yi\|Lee, Pao-Kung\|Chen, Shan-Na\|Cheng, Ying-Min\|Lee, Jenq-Chang\|Chang, Jang-Yang\|Liu, Tsang-Wu
PMID:	22223432

1272.
Journal:	Dis Colon Rectum. 2012 Feb;55(2):181-90.
Title:	Clinicopathologic and molecular characteristics of synchronous colorectal cancers: heterogeneity of clinical outcome depending on microsatellite instability status of individual tumors.
Author:	Bae, Jeong M\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong H
PMID:	22228162

1273.
Journal:	Clin Cancer Res. 2012 Feb 15;18(4):1177-85.
Title:	Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan.
Author:	Spindler, Karen-Lise Garm\|Pallisgaard, Niels\|Vogelius, Ivan\|Jakobsen, Anders
PMID:	22228631

1274.
Journal:	Curr Cancer Drug Targets. 2012 Feb;12(2):124-31.
Title:	Analysis of the concordance in the EGFR pathway status between primary tumors and related metastases of colorectal cancer patients:implications for cancer therapy.
Author:	Cejas, P\|Lopez-Gomez, M\|Aguayo, C\|Madero, R\|Moreno-Rubio, J\|de Castro Carpeno, J\|Belda-Iniesta, C\|Barriuso, J\|Moreno Garcia, V\|Diaz, E\|Burgos, E\|Gonzalez-Baron, M\|Feliu, J
PMID:	22229245

1275.
Journal:	Arch Pathol Lab Med. 2012 May;136(5):496-503.
Title:	Targeted therapies and predictive markers in epithelial malignancies of the gastrointestinal tract.
Author:	McIntire, Maria\|Redston, Mark
PMID:	22229849

1276.
Journal:	Am J Gastroenterol. 2012 Mar;107(3):460-9.
Title:	A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma.
Author:	Kimura, Tomoaki\|Yamamoto, Eiichiro\|Yamano, Hiro-O\|Suzuki, Hiromu\|Kamimae, Seiko\|Nojima, Masanori\|Sawada, Takeshi\|Ashida, Masami\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Kato, Ryusuke\|Harada, Taku\|Suzuki, Ryo\|Maruyama, Reo\|Kai, Masahiro\|Imai, Kohzoh\|Shinomura, Yasuh
PMID:	22233696

1277.
Journal:	Transplantation. 2012 Mar 15;93(5):509-17.
Title:	Role of oncogenic pathways and KRAS/BRAF mutations in the behavior of colon adenocarcinoma in renal transplant patients.
Author:	Revuelta, Ignacio\|Moya-Rull, Daniel\|Garcia-Herrera, Adriana\|Rovira, Jordi\|Ayala de la Pena, Francisco\|Misiego, Antonio\|Guzman, Flavia\|Oppenheimer, Federico\|Albanell, Joan\|Campistol, Josep M
PMID:	22245873

1278.
Journal:	J Natl Cancer Inst. 2012 Feb 8;104(3):228-39.
Title:	Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
Author:	Ihle, Nathan T\|Byers, Lauren A\|Kim, Edward S\|Saintigny, Pierre\|Lee, J Jack\|Blumenschein, George R\|Tsao, Anne\|Liu, Suyu\|Larsen, Jill E\|Wang, Jing\|Diao, Lixia\|Coombes, Kevin R\|Chen, Lu\|Zhang, Shuxing\|Abdelmelek, Mena F\|Tang, Ximing\|Papadimitrakopoulou, Vass
PMID:	22247021

1279.
Journal:	Singapore Med J. 2012 Jan;53(1):26-31.
Title:	Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer.
Author:	Zulhabri, O\|Rahman, J\|Ismail, S\|Isa, M R\|Wan Zurinah, W N
PMID:	22252179

1280.
Journal:	Biochem Soc Trans. 2012 Feb;40(1):73-8.
Title:	Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling.
Author:	Little, Annette S\|Balmanno, Kathryn\|Sale, Matthew J\|Smith, Paul D\|Cook, Simon J
PMID:	22260668

1281.
Journal:	Clin Cancer Res. 2012 Apr 15;18(8):2316-25.
Title:	The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer.
Author:	Shimizu, Toshio\|Tolcher, Anthony W\|Papadopoulos, Kyriakos P\|Beeram, Muralidhar\|Rasco, Drew W\|Smith, Lon S\|Gunn, Shelly\|Smetzer, Leslie\|Mays, Theresa A\|Kaiser, Brianne\|Wick, Michael J\|Alvarez, Cathy\|Cavazos, Aracely\|Mangold, Gina L\|Patnaik, Amita
PMID:	22261800

1282.
Journal:	Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):233-47.
Title:	Emerging role of cetuximab in the treatment of colorectal cancer.
Author:	Papa, Anselmo\|Rossi, Luigi\|Lo Russo, Giuseppe\|Giordani, Erika\|Spinelli, Gian Paolo\|Zullo, Angelo\|Petrozza, Vincenzo\|Tomao, Silverio
PMID:	22264223

1283.
Journal:	Digestion. 2012;85(2):99-102.
Title:	Search for novel target molecules for the effective treatment or prevention of colorectal cancer.
Author:	Tsujii, Masahiko
PMID:	22269287

1284.
Journal:	Invest New Drugs. 2012 Dec;30(6):2219-25.
Title:	Combination of ATP-competitive mammalian target of rapamycin inhibitors with standard chemotherapy for colorectal cancer.
Author:	Atreya, Chloe E\|Ducker, Gregory S\|Feldman, Morris E\|Bergsland, Emily K\|Warren, Robert S\|Shokat, Kevan M
PMID:	22270257

1285.
Journal:	Arch Pathol Lab Med. 2012 Oct;136(10):1298-307. Epub 2012 Jan 24.
Title:	Clinical implementation of KRAS testing in metastatic colorectal carcinoma: the pathologist's perspective.
Author:	Ross, Jeffrey S
PMID:	22272560

1286.
Journal:	Mod Pathol. 2012 May;25(5):731-9.
Title:	KRAS genotyping in rectal adenocarcinoma specimens with low tumor cellularity after neoadjuvant treatment.
Author:	Boissiere-Michot, Florence\|Lopez-Crapez, Evelyne\|Frugier, Helene\|Berthe, Marie-Laurence\|Ho-Pun-Cheung, Alexandre\|Assenat, Eric\|Maudelonde, Thierry\|Lamy, Pierre-Jean\|Bibeau, Frederic
PMID:	22282307

1287.
Journal:	Clin Cancer Res. 2012 Mar 15;18(6):1696-703.
Title:	Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer.
Author:	Kawada, Kenji\|Nakamoto, Yuji\|Kawada, Mayumi\|Hida, Koya\|Matsumoto, Takuya\|Murakami, Teppei\|Hasegawa, Suguru\|Togashi, Kaori\|Sakai, Yoshiharu
PMID:	22282467

1288.
Journal:	Clin Colorectal Cancer. 2012 Jun;11(2):143-50.
Title:	PTEN gene expression and mutations in the PIK3CA gene as predictors of clinical benefit to anti-epidermal growth factor receptor antibody therapy in patients with KRAS wild-type metastatic colorectal cancer.
Author:	Sood, Arjun\|McClain, Danielle\|Maitra, Radhashree\|Basu-Mallick, Atrayee\|Seetharam, Raviraja\|Kaubisch, Andreas\|Rajdev, Lakshmi\|Mariadason, John M\|Tanaka, Kathryn\|Goel, Sanjay
PMID:	22285706

1289.
Journal:	Onkologie. 2012;35 Suppl 1:42-8.
Title:	Personalized treatment of colorectal cancer.
Author:	Arnold, Dirk\|Stein, Alexander
PMID:	22286587

1290.
Journal:	Int J Cancer. 2012 Oct 15;131(8):1790-9.
Title:	Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.
Author:	Garcia-Solano, J\|Conesa-Zamora, P\|Carbonell, P\|Trujillo-Santos, J\|Torres-Moreno D, D\|Pagan-Gomez, I\|Rodriguez-Braun, E\|Perez-Guillermo, M
PMID:	22287190

1291.
Journal:	Diagn Mol Pathol. 2012 Mar;21(1):9-13.
Title:	Comparison of a PNA clamp PCR and an ARMS/Scorpion PCR assay for the detection of K-ras mutations.
Author:	Nordgard, Oddmund\|Oltedal, Satu\|Janssen, Emiel A M\|Gilje, Bjornar\|Korner, Hartwig\|Tjensvoll, Kjersti\|Smaaland, Rune
PMID:	22306670

1292.
Journal:	Diagn Mol Pathol. 2012 Mar;21(1):14-23.
Title:	KRAS mutation testing in colorectal cancer: comparison of the results obtained using 3 different methods for the analysis of codons G12 and G13.
Author:	Bihl, Michel P\|Hoeller, Sylvia\|Andreozzi, Maria Carla\|Foerster, Anja\|Rufle, Alexander\|Tornillo, Luigi\|Terracciano, Luigi
PMID:	22306671

1293.
Journal:	Am J Surg Pathol. 2012 May;36(5):744-52.
Title:	BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features.
Author:	Pai, Reetesh K\|Jayachandran, Priya\|Koong, Albert C\|Chang, Daniel T\|Kwok, Shirley\|Ma, Lisa\|Arber, Daniel A\|Balise, Raymond R\|Tubbs, Raymond R\|Shadrach, Bonnie\|Pai, Rish K
PMID:	22314188

1294.
Journal:	Cancer Res. 2012 Mar 15;72(6):1547-56.
Title:	Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling.
Author:	Horst, David\|Chen, Justina\|Morikawa, Teppei\|Ogino, Shuji\|Kirchner, Thomas\|Shivdasani, Ramesh A
PMID:	22318865

1295.
Journal:	Cancer Sci. 2012 Apr;103(4):791-6.
Title:	Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy.
Author:	Hsieh, Yao-Yu\|Tzeng, Cheng-Hwai\|Chen, Ming-Huang\|Chen, Po-Min\|Wang, Wei-Shu
PMID:	22321154

1296.
Journal:	Oncol Rep. 2012 May;27(5):1527-34.
Title:	NF-kappaB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IkappaBalpha pathway.
Author:	Lin, Gen\|Tang, Zhiwei\|Ye, Yun-Bin\|Chen, Qiang
PMID:	22327383

1297.
Journal:	Gan To Kagaku Ryoho. 2012 Feb;39(2):311-5.
Title:	[Pathologically complete response for unresectable stage IV rectal cancer using systemic chemotherapy with panitumumab - a case report].
Author:	Bamba, Takeo\|Suda, Takeyasu\|Nakano, Masato\|Terashima, Tetsuro\|Umezu, Hajime
PMID:	22333651

1298.
Journal:	Cancer Epidemiol Biomarkers Prev. 2012 Apr;21(4):681-4.
Title:	Postmenopausal hormone therapy and colorectal cancer risk in relation to somatic KRAS mutation status among older women.
Author:	Limburg, Paul J\|Limsui, David\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Cerhan, James R
PMID:	22337533

1299.
Journal:	Cell. 2012 Feb 17;148(4):639-50.
Title:	TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.
Author:	Singh, Anurag\|Sweeney, Michael F\|Yu, Min\|Burger, Alexa\|Greninger, Patricia\|Benes, Cyril\|Haber, Daniel A\|Settleman, Jeff
PMID:	22341439

1300.
Journal:	Am J Gastroenterol. 2012 May;107(5):782-9.
Title:	Cigarette smoking and colorectal cancer risk by KRAS mutation status among older women.
Author:	Samadder, N J\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Cerhan, James R\|Limburg, Paul J
PMID:	22349355

1301.
Journal:	Clin Cancer Res. 2012 Apr 15;18(8):2257-68.
Title:	Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.
Author:	Liao, Xiaoyun\|Morikawa, Teppei\|Lochhead, Paul\|Imamura, Yu\|Kuchiba, Aya\|Yamauchi, Mai\|Nosho, Katsuhiko\|Qian, Zhi Rong\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22357840

1302.
Journal:	Virchows Arch. 2012 Feb;460(2):129-30.
Title:	The times have changed: molecular pathology is here to stay. A commentary on: analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Le
Author:	van Krieken, J Han\|Hoefler, Gerald
PMID:	22358180

1303.
Journal:	Oncologist. 2012;17(3):339-45.
Title:	First-line cetuximab plus capecitabine in elderly patients with advanced colorectal cancer: clinical outcome and subgroup analysis according to KRAS status from a Spanish TTD Group Study.
Author:	Sastre, Javier\|Gravalos, Cristina\|Rivera, Fernando\|Massuti, Bartomeu\|Valladares-Ayerbes, Manuel\|Marcuello, Eugenio\|Manzano, Jose L\|Benavides, Manuel\|Hidalgo, Manuel\|Diaz-Rubio, Eduardo\|Aranda, Enrique
PMID:	22363067

1304.
Journal:	Expert Rev Mol Diagn. 2012 Mar;12(2):123-6.
Title:	KRAS mutational test for metastatic colorectal cancer patients: not just a technical problem.
Author:	Molinari, Francesca\|Frattini, Milo
PMID:	22369372

1305.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1223-30.
Title:	Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines.
Author:	Duerr, Eva-Maria\|Mizukami, Yusuke\|Moriichi, Kentaro\|Gala, Manish\|Jo, Won-Seok\|Kikuchi, Hirotoshi\|Xavier, Ramnik J\|Chung, Daniel C
PMID:	22383492

1306.
Journal:	Curr Cancer Drug Targets. 2012 May;12(4):316-28.
Title:	Patient-tailored treatments with anti-EGFR monoclonal antibodies in advanced colorectal cancer: KRAS and beyond.
Author:	Ballestrero, A\|Garuti, A\|Cirmena, G\|Rocco, I\|Palermo, C\|Nencioni, A\|Scabini, S\|Zoppoli, G\|Parodi, S\|Patrone, F
PMID:	22385512

1307.
Journal:	Clin Cancer Res. 2012 May 1;18(9):2515-25.
Title:	Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.
Author:	Migliardi, Giorgia\|Sassi, Francesco\|Torti, Davide\|Galimi, Francesco\|Zanella, Eugenia R\|Buscarino, Michela\|Ribero, Dario\|Muratore, Andrea\|Massucco, Paolo\|Pisacane, Alberto\|Risio, Mauro\|Capussotti, Lorenzo\|Marsoni, Silvia\|Di Nicolantonio, Federica\|Bardelli,
PMID:	22392911

1308.
Journal:	J Clin Oncol. 2012 Apr 20;30(12):1288-95.
Title:	Identification of a poor-prognosis BRAF-mutant-like population of patients with colon cancer.
Author:	Popovici, Vlad\|Budinska, Eva\|Tejpar, Sabine\|Weinrich, Scott\|Estrella, Heather\|Hodgson, Graeme\|Van Cutsem, Eric\|Xie, Tao\|Bosman, Fred T\|Roth, Arnaud D\|Delorenzi, Mauro
PMID:	22393095

1309.
Journal:	J Crohns Colitis. 2012 Jul;6(6):647-54.
Title:	Molecular alterations in colitis-associated colorectal neoplasia: study from a low prevalence area using magnifying chromo colonoscopy.
Author:	Shivakumar, Bhadravathi Marigowda\|Kumar, Balasubramanian Lakshman\|Bhat, Ganesh\|Suvarna, Deepak\|Rao, Lakshmi\|Pai, C Ganesh\|Satyamoorthy, Kapaettu
PMID:	22398042

1310.
Journal:	BMC Cancer. 2012 Mar 13;12:88.
Title:	Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases.
Author:	Kuramochi, Hidekazu\|Nakajima, Go\|Kaneko, Yuka\|Nakamura, Ayako\|Inoue, Yuji\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	22409860

1311.
Journal:	J Clin Oncol. 2012 May 1;30(13):1505-12.
Title:	Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer.
Author:	Weickhardt, Andrew J\|Price, Tim J\|Chong, Geoff\|Gebski, Val\|Pavlakis, Nick\|Johns, Terrance G\|Azad, Arun\|Skrinos, Effie\|Fluck, Kate\|Dobrovic, Alexander\|Salemi, Renato\|Scott, Andrew M\|Mariadason, John M\|Tebbutt, Niall C
PMID:	22412142

1312.
Journal:	J Mol Diagn. 2012 May-Jun;14(3):187-91.
Title:	Implementation of formalin-fixed, paraffin-embedded cell line pellets as high-quality process controls in quality assessment programs for KRAS mutation analysis.
Author:	Dijkstra, Jeroen R\|Opdam, Frank J M\|Boonyaratanakornkit, Jerry\|Schonbrunner, E Ralf\|Shahbazian, Mona\|Edsjo, Anders\|Hoefler, Gerald\|Jung, Andreas\|Kotsinas, Athanassios\|Gorgoulis, Vassilis G\|Lopez-Rios, Fernando\|de Stricker, Karin\|Rouleau, Etienne\|Biesmans,
PMID:	22414609

1313.
Journal:	Ther Adv Med Oncol. 2012 Mar;4(2):75-89.
Title:	Therapeutic strategy in unresectable metastatic colorectal cancer.
Author:	Chibaudel, Benoist\|Tournigand, Christophe\|Andre, Thierry\|de Gramont, Aimery
PMID:	22423266

1314.
Journal:	Int J Biol Markers. 2012 Jan-Mar;27(1):27-33.
Title:	Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.
Author:	Bagadi, Sarita B\|Sanghvi, Meera\|Nair, Sudish B\|Das, Bibhu R
PMID:	22427190

1315.
Journal:	Oncol Rep. 2012 Jun;27(6):1887-92.
Title:	Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment.
Author:	Oliveras-Ferraros, Cristina\|Massaguer Vall-Llovera, Anna\|Vazquez-Martin, Alejandro\|Salip, Dolors Carrion\|Queralt, Bernardo\|Cufi, Silvia\|Martin-Castillo, Begona\|Bosch-Barrera, Joaquim\|Brunet, Joan\|De Llorens, Rafael\|Menendez, Javier A
PMID:	22427198

1316.
Journal:	Gut. 2012 Jun;61(6):847-54.
Title:	Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum.
Author:	Yamauchi, Mai\|Morikawa, Teppei\|Kuchiba, Aya\|Imamura, Yu\|Qian, Zhi Rong\|Nishihara, Reiko\|Liao, Xiaoyun\|Waldron, Levi\|Hoshida, Yujin\|Huttenhower, Curtis\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles\|Ogino, Shuji
PMID:	22427238

1317.
Journal:	Int J Colorectal Dis. 2012 Oct;27(10):1325-32.
Title:	Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study.
Author:	Sun, Pei-Long\|Li, Bing\|Ye, Qi-Fa
PMID:	22430888

1318.
Journal:	J Exp Clin Cancer Res. 2012 Mar 23;31:26.
Title:	Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer.
Author:	Shojaei, Farbod\|Scott, Nathan\|Kang, Xiaolin\|Lappin, Patrick B\|Fitzgerald, Amanda A\|Karlicek, Shannon\|Simmons, Brett H\|Wu, Aidong\|Lee, Joseph H\|Bergqvist, Simon\|Kraynov, Eugenia
PMID:	22444159

1319.
Journal:	Eur J Cancer. 2012 May;48(7):1108-15.
Title:	Concordance in KRAS and BRAF mutations in endoscopic biopsy samples and resection specimens of colorectal adenocarcinoma.
Author:	Krol, L C\|'t Hart, N A\|Methorst, N\|Knol, A J\|Prinsen, C\|Boers, J E
PMID:	22446020

1320.
Journal:	J Exp Med. 2012 Apr 9;209(4):697-711.
Title:	Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.
Author:	Azoitei, Ninel\|Hoffmann, Christopher M\|Ellegast, Jana M\|Ball, Claudia R\|Obermayer, Kerstin\|Gossele, Ulrike\|Koch, Britta\|Faber, Katrin\|Genze, Felicitas\|Schrader, Mark\|Kestler, Hans A\|Dohner, Hartmut\|Chiosis, Gabriela\|Glimm, Hanno\|Frohling, Stefan\|Scholl, C
PMID:	22451720

1321.
Journal:	Respirology. 2012 Oct;17(7):1048-59.
Title:	Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis.
Author:	Sato, Mitsuo\|Shames, David S\|Hasegawa, Yoshinori
PMID:	22452538

1322.
Journal:	J Clin Pathol. 2012 Jul;65(7):604-7.
Title:	KRAS mutational status of endoscopic biopsies matches resection specimens.
Author:	Yang, Qing-Hua\|Schmidt, Jason\|Soucy, Genvieve\|Odze, Robert\|Dejesa-Jamanila, Liza\|Arnold, Keely\|Kuslich, Christine\|Lash, Richard
PMID:	22461648

1323.
Journal:	Med Oncol. 2012 Dec;29(4):2864-5.
Title:	Three different KRAS statuses in three synchronous colorectal cancers.
Author:	Jolissaint, L\|Cacheux, W\|Mariani, P\|Le Tourneau, C\|Lievre, A\|Lappartient, E\|Margogne, A\|Farkhondeh, F\|de Cremoux, P
PMID:	22467075

1324.
Journal:	J Clin Oncol. 2012 May 10;30(14):1620-7.
Title:	Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C).
Author:	Dewdney, Alice\|Cunningham, David\|Tabernero, Josep\|Capdevila, Jaume\|Glimelius, Bengt\|Cervantes, Andres\|Tait, Diana\|Brown, Gina\|Wotherspoon, Andrew\|Gonzalez de Castro, David\|Chua, Yu Jo\|Wong, Rachel\|Barbachano, Yolanda\|Oates, Jacqueline\|Chau, Ian
PMID:	22473163

1325.
Journal:	JAMA. 2012 Apr 4;307(13):1383-93.
Title:	Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial.
Author:	Alberts, Steven R\|Sargent, Daniel J\|Nair, Suresh\|Mahoney, Michelle R\|Mooney, Margaret\|Thibodeau, Stephen N\|Smyrk, Thomas C\|Sinicrope, Frank A\|Chan, Emily\|Gill, Sharlene\|Kahlenberg, Morton S\|Shields, Anthony F\|Quesenberry, James T\|Webb, Thomas A\|Farr, Gist
PMID:	22474202

1326.
Journal:	Mod Pathol. 2012 Aug;25(8):1128-39.
Title:	Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features.
Author:	Chang, Daniel T\|Pai, Rish K\|Rybicki, Lisa A\|Dimaio, Michael A\|Limaye, Maneesha\|Jayachandran, Priya\|Koong, Albert C\|Kunz, Pamela A\|Fisher, George A\|Ford, James M\|Welton, Mark\|Shelton, Andrew\|Ma, Lisa\|Arber, Daniel A\|Pai, Reetesh K
PMID:	22481281

1327.
Journal:	Neoplasma. 2012;59(4):376-83.
Title:	Mutation pattern of KRAS and BRAF oncogenes in colorectal cancer patients.
Author:	Rako, I\|Jakic-Razumovic, J\|Katalinic, D\|Sertic, J\|Plestina, S
PMID:	22489692

1328.
Journal:	J Transl Med. 2012 Apr 10;10:71.
Title:	Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab.
Author:	Scartozzi, Mario\|Giampieri, Riccardo\|Maccaroni, Elena\|Mandolesi, Alessandra\|Biagetti, Simona\|Alfonsi, Simona\|Giustini, Lucio\|Loretelli, Cristian\|Faloppi, Luca\|Bittoni, Alessandro\|Bianconi, Maristella\|Del Prete, Michela\|Bearzi, Italo\|Cascinu, Stefano
PMID:	22490361

1329.
Journal:	Anticancer Res. 2012 Apr;32(4):1457-61.
Title:	Comparison of the chemosensitivity of the primary lesion and a pancreatic metastasis of colon cancer: a case report.
Author:	Tamagawa, Hiroshi\|Miyagi, Yohei\|Numata, Masakatsu\|Yamamoto, Naoto\|Shiozawa, Manabu\|Morinaga, Soichiro\|Sekiyama, Akiko\|Sekiguchi, Hironobu\|Sakuma, Yuji\|Kameda, Yoichi\|Akaike, Makoto\|Masuda, Munetaka\|Imada, Toshio
PMID:	22493386

1330.
Journal:	Clin Cancer Res. 2012 Jun 1;18(11):3132-41.
Title:	Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.
Author:	Kemper, Kristel\|Versloot, Miranda\|Cameron, Katherine\|Colak, Selcuk\|de Sousa e Melo, Felipe\|de Jong, Joan H\|Bleackley, Joanne\|Vermeulen, Louis\|Versteeg, Rogier\|Koster, Jan\|Medema, Jan Paul
PMID:	22496204

1331.
Journal:	Neoplasia. 2012 Mar;14(3):190-205.
Title:	Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPbeta-dependent suppression of EGFR expression.
Author:	Derer, Stefanie\|Berger, Sven\|Schlaeth, Martin\|Schneider-Merck, Tanja\|Klausz, Katja\|Lohse, Stefan\|Overdijk, Marije B\|Dechant, Michael\|Kellner, Christian\|Nagelmeier, Iris\|Scheel, Andreas H\|Lammerts van Bueren, Jeroen J\|van de Winkel, Jan G J\|Parren, Paul W
PMID:	22496619

1332.
Journal:	Int J Oncol. 2012 Jul;41(1):285-91.
Title:	Use of multiple biomarkers for the localization and characterization of colon cancer stem cells by indirect immunocytochemistry.
Author:	Amsterdam, Abraham\|Raanan, Calanit\|Schreiber, Letizia\|Freyhan, Ora\|Fabrikant, Yakov\|Melzer, Ehud
PMID:	22504585

1333.
Journal:	Arch Surg. 2012 Aug;147(8):715-23.
Title:	Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.
Author:	Morikawa, Teppei\|Tanaka, Noriko\|Kuchiba, Aya\|Nosho, Katsuhiko\|Yamauchi, Mai\|Hornick, Jason L\|Swanson, Richard S\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Huttenhower, Curtis\|Schrag, Deborah\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22508672

1334.
Journal:	Am J Surg Pathol. 2012 Jun;36(6):876-82.
Title:	Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics.
Author:	Rosty, Christophe\|Buchanan, Daniel D\|Walsh, Michael D\|Pearson, Sally-Ann\|Pavluk, Erika\|Walters, Rhiannon J\|Clendenning, Mark\|Spring, Kevin J\|Jenkins, Mark A\|Win, Aung K\|Hopper, John L\|Sweet, Kevin\|Frankel, Wendy L\|Aronson, Melyssa\|Gallinger, Steve\|Goldbla
PMID:	22510757

1335.
Journal:	Future Oncol. 2012 Apr;8(4):373-89.
Title:	Panitumumab: a summary of clinical development in colorectal cancer and future directions.
Author:	Argiles, Guillem\|Dienstmann, Rodrigo\|Elez, Elena\|Tabernero, Josep
PMID:	22515440

1336.
Journal:	Curr Cancer Drug Targets. 2012 Sep;12(7):873-98.
Title:	A molecular signature for oncogenic BRAF in human colon cancer cells is revealed by microarray analysis.
Author:	Joyce, T\|Oikonomou, E\|Kosmidou, V\|Makrodouli, E\|Bantounas, I\|Avlonitis, S\|Zografos, G\|Pintzas, A
PMID:	22515520

1337.
Journal:	J BUON. 2012 Jan-Mar;17(1):73-8.
Title:	Meta-analysis of the predictive value of KRAS mutations in treatment response using cetuximab in colorectal cancer.
Author:	Tsoukalas, N\|Tzovaras, A A\|Tolia, M\|Kostakis, I D\|Papakostidi, A\|Pistamaltzian, N\|Ardavanis, A
PMID:	22517696

1338.
Journal:	Dig Dis Sci. 2012 Sep;57(9):2325-33.
Title:	KRAS mutation and NF-kappaB activation indicates tolerance of chemotherapy and poor prognosis in colorectal cancer.
Author:	Lin, Gen\|Zheng, Xiong-Wei\|Li, Chao\|Chen, Qiang\|Ye, Yun-Bin
PMID:	22526587

1339.
Journal:	Br J Cancer. 2012 May 22;106(11):1826-32.
Title:	Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.
Author:	Pichler, M\|Winter, E\|Stotz, M\|Eberhard, K\|Samonigg, H\|Lax, S\|Hoefler, G
PMID:	22549179

1340.
Journal:	Oncol Rep. 2012 Jul;28(1):15-20.
Title:	Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Author:	Li, Bo\|Gao, Shuohui\|Wei, Feng\|Bellail, Anita C\|Hao, Chunhai\|Liu, Tongjun
PMID:	22552366

1341.
Journal:	Diagn Mol Pathol. 2012 Jun;21(2):114-9.
Title:	Applicability of a System for fully automated nucleic acid extraction from formalin-fixed paraffin-embedded sections for routine KRAS mutation testing.
Author:	Lehmann, Annika\|Schewe, Christiane\|Hennig, Guido\|Denkert, Carsten\|Weichert, Wilko\|Budczies, Jan\|Dietel, Manfred
PMID:	22555094

1342.
Journal:	Gastrointest Cancer Res. 2012 Jan;5(1):19-27.
Title:	Genetic alterations in colorectal cancer.
Author:	Armaghany, Tannaz\|Wilson, Jon D\|Chu, Quyen\|Mills, Glenn
PMID:	22574233

1343.
Journal:	Clin Chim Acta. 2012 Oct 9;413(19-20):1605-11.
Title:	Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.
Author:	Hsieh, Li-Ling\|Er, Tze-Kiong\|Chen, Chih-Chieh\|Hsieh, Jan-Sing\|Chang, Jan-Gowth\|Liu, Ta-Chih
PMID:	22579930

1344.
Journal:	Int J Oncol. 2012 Aug;41(2):583-8.
Title:	Differential response to EGFR- and VEGF-targeted therapies in patient-derived tumor tissue xenograft models of colon carcinoma and related metastases.
Author:	Jin, Ketao\|Lan, Huanrong\|Cao, Feilin\|Han, Na\|Xu, Zhenzhen\|Li, Guangliang\|He, Kuifeng\|Teng, Lisong
PMID:	22581265

1345.
Journal:	APMIS. 2012 Jun;120(6):459-68.
Title:	K-ras mutations are correlated to lymph node metastasis and tumor stage, but not to the growth pattern of colon carcinoma.
Author:	Mannan, Abdul\|Hahn-Stromberg, Victoria
PMID:	22583358

1346.
Journal:	Oncologist. 2012;17(6):823-9.
Title:	High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease.
Author:	Ruzzo, Annamaria\|Graziano, Francesco\|Vincenzi, Bruno\|Canestrari, Emanuele\|Perrone, Giuseppe\|Galluccio, Nadia\|Catalano, Vincenzo\|Loupakis, Fotios\|Rabitti, Carla\|Santini, Daniele\|Tonini, Giuseppe\|Fiorentini, Giammaria\|Rossi, David\|Falcone, Alfredo\|Magnani,
PMID:	22584434

1347.
Journal:	PLoS One. 2012;7(5):e36653.
Title:	KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.
Author:	Mao, Chen\|Zhou, Junhua\|Yang, Zuyao\|Huang, Yafang\|Wu, Xinyin\|Shen, Hong\|Tang, Jinling\|Chen, Qing
PMID:	22586484

1348.
Journal:	Anticancer Res. 2012 May;32(5):1621-6.
Title:	Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients.
Author:	Levy, Miroslav\|Benesova, Lucie\|Lipska, Ludmila\|Belsanova, Barbora\|Minarikova, Petra\|Veprekova, Gabriela\|Zavoral, Miroslav\|Minarik, Marek
PMID:	22593440

1349.
Journal:	Expert Opin Biol Ther. 2012 Jun;12 Suppl 1:S209-15.
Title:	The importance of examining the proportion of circulating DNA originating from tumor, microenvironment and normal cells in colorectal cancer patients.
Author:	Mouliere, Florent\|Thierry, Alain R
PMID:	22594497

1350.
Journal:	Food Funct. 2012 Aug;3(8):844-52.
Title:	Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway.
Author:	Xavier, Cristina P R\|Lima, Cristovao F\|Fernandes-Ferreira, Manuel\|Pereira-Wilson, Cristina
PMID:	22596086

1351.
Journal:	Clin Colorectal Cancer. 2012 Dec;11(4):280-90.
Title:	High-resolution melting assay (HRMA) is a simple and sensitive stool-based DNA Test for the detection of mutations in colorectal neoplasms.
Author:	Li, Bing-Sheng\|Wang, Xin-Ying\|Xu, An-Gao\|Ma, Feng-Li\|Ma, Qun-Ying\|Li, Zao\|Liu, Ji-Hong\|Gan, Ai-Hua\|Yu, Zhi-Jin\|Zhang, Xiao-Hui\|Jiang, Bo
PMID:	22609129

1352.
Journal:	Cancer Chemother Pharmacol. 2012 Jun;69(6):1647-55.
Title:	Loss of PTEN expression as a predictor of resistance to anti-EGFR monoclonal therapy in metastatic colorectal cancer: evidence from retrospective studies.
Author:	Wang, Zhen-Hua\|Gao, Qin-Yan\|Fang, Jing-Yuan
PMID:	22610356

1353.
Journal:	Cell Res. 2012 Aug;22(8):1227-45.
Title:	Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.
Author:	Steckel, Michael\|Molina-Arcas, Miriam\|Weigelt, Britta\|Marani, Michaela\|Warne, Patricia H\|Kuznetsov, Hanna\|Kelly, Gavin\|Saunders, Becky\|Howell, Michael\|Downward, Julian\|Hancock, David C
PMID:	22613949

1354.
Journal:	Ann Surg Oncol. 2012 Oct;19(11):3441-8.
Title:	Clinical outcomes of patients with microsatellite-unstable colorectal carcinomas depend on L1 methylation level.
Author:	Rhee, Ye-Young\|Kim, Mi Jung\|Bae, Jeong Mo\|Koh, Jae Moon\|Cho, Nam-Yun\|Juhnn, Yong-Sung\|Kim, Donguk\|Kang, Gyeong Hoon
PMID:	22618722

1355.
Journal:	Nihon Rinsho. 2012 May;70(5):802-8.
Title:	[Biomarker for colorectal cancer].
Author:	Nagasaka, Takeshi\|Mori, Yoshiko\|Umeda, Yuzo\|Fujiwara, Toshiyoshi
PMID:	22620004

1356.
Journal:	Oncol Rep. 2012 Aug;28(2):473-80.
Title:	Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer.
Author:	Kuno, Takashi\|Matsubara, Nagahide\|Tsuda, Satoshi\|Kobayashi, Masayoshi\|Hamanaka, Mie\|Yamagishi, Daisuke\|Tsukamoto, Kiyoshi\|Yamano, Tomoki\|Noda, Masafumi\|Ikeuchi, Hiroki\|Kim, Sanghyuk\|Tamura, Kazuo\|Tomita, Naohiro
PMID:	22641385

1357.
Journal:	Anticancer Res. 2012 Jun;32(6):2271-5.
Title:	KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells.
Author:	Ota, Takeharu\|Doi, Keiko\|Fujimoto, Takahiro\|Tanaka, Yoko\|Ogawa, Masahiro\|Matsuzaki, Hiroshi\|Kuroki, Masahide\|Miyamoto, Shingo\|Shirasawa, Senji\|Tsunoda, Toshiyuki
PMID:	22641662

1358.
Journal:	Anticancer Res. 2012 Jun;32(6):2301-8.
Title:	ALPK2 is crucial for luminal apoptosis and DNA repair-related gene expression in a three-dimensional colonic-crypt model.
Author:	Yoshida, Yasuhiro\|Tsunoda, Toshiyuki\|Doi, Keiko\|Fujimoto, Takahiro\|Tanaka, Yoko\|Ota, Takeharu\|Ogawa, Masahiro\|Matsuzaki, Hiroshi\|Kuroki, Masahide\|Iwasaki, Akinori\|Shirasawa, Senji
PMID:	22641666

1359.
Journal:	Vestn Ross Akad Med Nauk. 2012;(2):35-41.
Title:	[Comparison of different methods of molecular-genetic analysis of somatic mutations in K-ras gene in patients with colorectal cancer].
Author:	Amosenko, F A\|Karpov, I V\|Poliakov, A V\|Kovalenko, S P\|Shamanin, V A\|Liubchenko, L N
PMID:	22642176

1360.
Journal:	Gastroenterology. 2012 Sep;143(3):730-740.
Title:	A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans.
Author:	Bongers, Gerold\|Muniz, Luciana R\|Pacer, Michelle E\|Iuga, Alina C\|Thirunarayanan, Nanthakumar\|Slinger, Erik\|Smit, Martine J\|Reddy, E Premkumar\|Mayer, Lloyd\|Furtado, Glaucia C\|Harpaz, Noam\|Lira, Sergio A
PMID:	22643351

1361.
Journal:	Front Oncol. 2012 Feb 27;2:7.
Title:	Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Terracciano, Luigi\|Lugli, Alessandro
PMID:	22655257

1362.
Journal:	J Mol Med (Berl). 2012 Dec;90(12):1421-38.
Title:	Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors.
Author:	Ragusa, Marco\|Statello, Luisa\|Maugeri, Marco\|Majorana, Alessandra\|Barbagallo, Davide\|Salito, Loredana\|Sammito, Mariangela\|Santonocito, Manuela\|Angelica, Rosario\|Cavallaro, Andrea\|Scalia, Marina\|Caltabiano, Rosario\|Privitera, Giuseppe\|Biondi, Antonio\|Di Vi
PMID:	22660396

1363.
Journal:	J Clin Oncol. 2012 Aug 20;30(24):2956-62.
Title:	Comparative genomic analysis of primary versus metastatic colorectal carcinomas.
Author:	Vakiani, Efsevia\|Janakiraman, Manickam\|Shen, Ronglai\|Sinha, Rileen\|Zeng, Zhaoshi\|Shia, Jinru\|Cercek, Andrea\|Kemeny, Nancy\|D'Angelica, Michael\|Viale, Agnes\|Heguy, Adriana\|Paty, Philip\|Chan, Timothy A\|Saltz, Leonard B\|Weiser, Martin\|Solit, David B
PMID:	22665543

1364.
Journal:	Dig Dis Sci. 2012 Nov;57(11):2863-72.
Title:	Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia.
Author:	Abdul Murad, Nor Azian\|Othman, Zulhabri\|Khalid, Melati\|Abdul Razak, Zuraini\|Hussain, Rosniza\|Nadesan, Sukumar\|Sagap, Ismail\|Mohamed Rose, Isa\|Wan Ngah, Wan Zurinah\|Jamal, Rahman
PMID:	22669205

1365.
Journal:	Cancer. 2012 Dec 15;118(24):6144-51.
Title:	Safety, pharmacokinetics, and activity of EZN-2208, a novel conjugate of polyethylene glycol and SN38, in patients with advanced malignancies.
Author:	Kurzrock, Razelle\|Goel, Sanjay\|Wheler, Jennifer\|Hong, David\|Fu, Siqing\|Rezai, Keyvan\|Morgan-Linnell, Sonia K\|Urien, Saik\|Mani, Sridhar\|Chaudhary, Imran\|Ghalib, Mohammed H\|Buchbinder, Aby\|Lokiec, Francois\|Mulcahy, Mary
PMID:	22674635

1366.
Journal:	PLoS One. 2012;7(5):e38033.
Title:	KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors.
Author:	Garrido-Laguna, Ignacio\|Hong, David S\|Janku, Filip\|Nguyen, Ly M\|Falchook, Gerald S\|Fu, Siqing\|Wheler, Jenifer J\|Luthra, Rajyalakshmi\|Naing, Aung\|Wang, Xuemei\|Kurzrock, Razelle
PMID:	22675430

1367.
Journal:	PLoS One. 2012;7(6):e38422.
Title:	Histological and molecular evaluation of patient-derived colorectal cancer explants.
Author:	Uronis, Joshua M\|Osada, Takuya\|McCall, Shannon\|Yang, Xiao Yi\|Mantyh, Christopher\|Morse, Michael A\|Lyerly, H Kim\|Clary, Bryan M\|Hsu, David S
PMID:	22675560

1368.
Journal:	World J Gastroenterol. 2012 Jun 7;18(21):2712-8.
Title:	Phosphatase and tensin homolog expression related to cetuximab effects in colorectal cancer patients: a meta-analysis.
Author:	Shen, Yue\|Yang, Jian\|Xu, Zhi\|Gu, Dong-Ying\|Chen, Jin-Fei
PMID:	22690082

1369.
Journal:	Carcinogenesis. 2012 Sep;33(9):1782-90.
Title:	Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Author:	Gulhati, Pat\|Zaytseva, Yekaterina Y\|Valentino, Joseph D\|Stevens, Payton D\|Kim, Ji Tae\|Sasazuki, Takehiko\|Shirasawa, Senji\|Lee, Eun Y\|Weiss, Heidi L\|Dong, Jianli\|Gao, Tianyan\|Evers, B Mark
PMID:	22696593

1370.
Journal:	Adv Gerontol. 2012;25(1):72-8.
Title:	[Age-related and clinical-pathogenetic features of colorectal cancer associated with status of K-ras gene].
Author:	Beliaeva, A V\|Ianus, G A\|Suspithyn, E N\|Zaitseva, O A\|Iatsuk, O S\|Moiseenko, A B\|Guliaev, A V\|Imianitov, E N
PMID:	22708448

1371.
Journal:	Drugs. 2012 Jun 19;72 Suppl 1:28-36.
Title:	Prognostic and predictive value of K-RAS mutations in non-small cell lung cancer.
Author:	Califano, Raffaele\|Landi, Lorenza\|Cappuzzo, Federico
PMID:	22712795

1372.
Journal:	Br J Cancer. 2012 Jul 10;107(2):345-51.
Title:	A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens.
Author:	Gonzalez de Castro, D\|Angulo, B\|Gomez, B\|Mair, D\|Martinez, R\|Suarez-Gauthier, A\|Shieh, F\|Velez, M\|Brophy, V H\|Lawrence, H J\|Lopez-Rios, F
PMID:	22713664

1373.
Journal:	Small GTPases. 2012 Jan-Mar;3(1):34-9.
Title:	KRAS mutant colorectal tumors: past and present.
Author:	Brand, Toni M\|Wheeler, Deric L
PMID:	22714415

1374.
Journal:	Anal Chem. 2012 Jul 3;84(13):5645-52.
Title:	Digital detection of multiple minority mutants in stool DNA for noninvasive colorectal cancer diagnosis.
Author:	Deng, Lili\|Qi, Zongtai\|Zou, Binjie\|Wu, Haiping\|Huang, Huan\|Kajiyama, Tomoharu\|Kambara, Hideki\|Zhou, Guohua
PMID:	22715805

1375.
Journal:	Nature. 2012 Jun 28;486(7404):532-6.
Title:	Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
Author:	Misale, Sandra\|Yaeger, Rona\|Hobor, Sebastijan\|Scala, Elisa\|Janakiraman, Manickam\|Liska, David\|Valtorta, Emanuele\|Schiavo, Roberta\|Buscarino, Michela\|Siravegna, Giulia\|Bencardino, Katia\|Cercek, Andrea\|Chen, Chin-Tung\|Veronese, Silvio\|Zanon, Carlo\|Sartore-B
PMID:	22722830

1376.
Journal:	Mol Cancer Ther. 2012 Sep;11(9):2062-71.
Title:	Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.
Author:	Dienstmann, Rodrigo\|Serpico, Danila\|Rodon, Jordi\|Saura, Cristina\|Macarulla, Teresa\|Elez, Elena\|Alsina, Maria\|Capdevila, Jaume\|Perez-Garcia, Jose\|Sanchez-Olle, Gessami\|Aura, Claudia\|Prudkin, Ludmila\|Landolfi, Stefania\|Hernandez-Losa, Javier\|Vivancos, Ana\|T
PMID:	22723336

1377.
Journal:	Pathol Oncol Res. 2012 Oct;18(4):1077-84. Epub 2012 Jun 23.
Title:	Characteristics of advanced- and non advanced sporadic polypoid colorectal adenomas: correlation to KRAS mutations.
Author:	Yadamsuren, Enkh-Amar\|Nagy, Szilvia\|Pajor, Laszlo\|Lacza, Agnes\|Bogner, Barna
PMID:	22729813

1378.
Journal:	J Hepatobiliary Pancreat Sci. 2012 Sep;19(5):528-35.
Title:	Selecting the best targeted agent in first-line treatment of unresectable liver metastases from colorectal cancer: does the bench have the answers?
Author:	Benhaim, L\|Loupakis, F\|Labonte, M J\|Lenz, H J
PMID:	22735932

1379.
Journal:	Oncol Lett. 2012 Feb;3(2):269-272.
Title:	Good response to leucovorin and fluorouracil plus oxaliplatin and cetuximab therapy in a patient with metastatic ascending colon cancer harboring a KRAS p.G13D mutation.
Author:	Ochiai, Takumi\|Nishimura, Kazuhiko\|Watanabe, Tomoo\|Kitajima, Masayuki\|Nakatani, Akinori\|Inou, Takashi\|Washio, Marie\|Sakuyama, Naoki\|Sato, Tsuyoshi\|Kishine, Kenji\|Ochi, Takanori\|Ookubo, Satoshi\|Futagawa, Shunji\|Orikasa, Hideki\|Mashiko, Satomi\|Nagaoka, Isao
PMID:	22740893

1380.
Journal:	Oncol Lett. 2012 Mar;3(3):565-570.
Title:	PIK3CA mutation and methylation influences the outcome of colorectal cancer.
Author:	Iida, Satoru\|Kato, Shunsuke\|Ishiguro, Megumi\|Matsuyama, Takatoshi\|Ishikawa, Toshiaki\|Kobayashi, Hirotoshi\|Higuchi, Tetsuro\|Uetake, Hiroyuki\|Enomoto, Masayuki\|Sugihara, Kenichi
PMID:	22740953

1381.
Journal:	Oncol Lett. 2012 Mar;3(3):649-653.
Title:	Acquired/intratumoral mutation of KRAS during metastatic progression of colorectal carcinogenesis.
Author:	Otsuka, Kazunori\|Satoyoshi, Rika\|Nanjo, Hiroshi\|Miyazawa, Hideaki\|Abe, Yuki\|Tanaka, Masamitsu\|Yamamoto, Yuzo\|Shibata, Hiroyuki
PMID:	22740969

1382.
Journal:	Clin Chem. 2012 Sep;58(9):1332-41.
Title:	Nanofluidic digital PCR for KRAS mutation detection and quantification in gastrointestinal cancer.
Author:	Azuara, Daniel\|Ginesta, Mireia M\|Gausachs, Mireia\|Rodriguez-Moranta, Francisco\|Fabregat, Joan\|Busquets, Juli\|Pelaez, Nuria\|Boadas, Jaume\|Galter, Sara\|Moreno, Victor\|Costa, Jose\|de Oca, Javier\|Capella, Gabriel
PMID:	22745110

1383.
Journal:	Ann Surg Oncol. 2012 Nov;19(12):3719-26.
Title:	Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.
Author:	Nordgard, Oddmund\|Oltedal, Satu\|Aasprong, Ole Gunnar\|Soreide, Jon Arne\|Soreide, Kjetil\|Tjensvoll, Kjersti\|Gilje, Bjornar\|Heikkila, Reino\|Guriby, Marianne\|Lothe, Ragnhild A\|Smaaland, Rune\|Korner, Hartwig
PMID:	22752373

1384.
Journal:	Mol Cancer Ther. 2012 Sep;11(9):1884-93.
Title:	Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the betaGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo.
Author:	Mallucci, Livio\|Shi, Dong-yun\|Davies, Derek\|Jordan, Peter\|Nicol, Alastair\|Lotti, Lavinia\|Mariani-Costantini, Renato\|Verginelli, Fabio\|Wells, Valerie\|Zicha, Daniel
PMID:	22752425

1385.
Journal:	Clin Cancer Res. 2012 Sep 1;18(17):4753-63.
Title:	Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.
Author:	Imamura, Yu\|Morikawa, Teppei\|Liao, Xiaoyun\|Lochhead, Paul\|Kuchiba, Aya\|Yamauchi, Mai\|Qian, Zhi Rong\|Nishihara, Reiko\|Meyerhardt, Jeffrey A\|Haigis, Kevin M\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22753589

1386.
Journal:	Anticancer Res. 2012 Jul;32(7):2585-90.
Title:	A significant role of lipogenic enzymes in colorectal cancer.
Author:	Notarnicola, Maria\|Messa, Caterina\|Caruso, Maria Gabriella
PMID:	22753716

1387.
Journal:	BMC Genomics. 2012 Jun 18;13 Suppl 4:S9.
Title:	Domain landscapes of somatic mutations in cancer.
Author:	Nehrt, Nathan L\|Peterson, Thomas A\|Park, DoHwan\|Kann, Maricel G
PMID:	22759657

1388.
Journal:	In Vivo. 2012 Jul-Aug;26(4):537-47.
Title:	A comprehensive procedural approach to genotyping KRAS and BRAF from paraffin embedded tissues for diagnostic purposes.
Author:	Palmirotta, Raffaele\|Ludovici, Giorgia\|De Marchis, Maria Laura\|Leone, Barbara\|Formica, Vincenzo\|Ettorre, Giuseppe Maria\|Cavaliere, Francesco\|Della-Morte, David\|Ferroni, Patrizia\|Roselli, Mario\|Guadagni, Fiorella
PMID:	22773565

1389.
Journal:	Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2127-33.
Title:	Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.
Author:	Ohashi, Kadoaki\|Sequist, Lecia V\|Arcila, Maria E\|Moran, Teresa\|Chmielecki, Juliann\|Lin, Ya-Lun\|Pan, Yumei\|Wang, Lu\|de Stanchina, Elisa\|Shien, Kazuhiko\|Aoe, Keisuke\|Toyooka, Shinichi\|Kiura, Katsuyuki\|Fernandez-Cuesta, Lynnette\|Fidias, Panos\|Yang, James Chi
PMID:	22773810

1390.
Journal:	Gan To Kagaku Ryoho. 2012 Jul;39(7):1147-9.
Title:	[A case report of advanced mucinous adenocarcinoma of the transverse colon with peritoneal dissemination effectively treated by multidisciplinary approach with a focus on FOLFOX4 therapy combined with panitumumab].
Author:	Asano, Tomonari\|Negita, Masataka\|Uemura, Takanori\|Takagi, Daishi\|Hattori, Masashi\|Kamiya, Isao
PMID:	22790058

1391.
Journal:	Small GTPases. 2012 Apr-Jun;3(2):126-30.
Title:	Differential involvement of RalA and RalB in colorectal cancer.
Author:	Martin, Timothy D\|Der, Channing J
PMID:	22790202

1392.
Journal:	Chemother Res Pract. 2012;2012:359041.
Title:	CpG Island Methylation, Microsatellite Instability, and BRAF Mutations and Their Clinical Application in the Treatment of Colon Cancer.
Author:	Wu, Christina\|Bekaii-Saab, Tanios
PMID:	22792460

1393.
Journal:	Oncol Rep. 2012 Oct;28(4):1187-92.
Title:	KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung.
Author:	Yokota, Keisuke\|Sasaki, Hidefumi\|Okuda, Katsuhiro\|Shimizu, Shigeki\|Shitara, Masayuki\|Hikosaka, Yu\|Moriyama, Satoru\|Yano, Motoki\|Fujii, Yoshitaka
PMID:	22797671

1394.
Journal:	J Proteomics. 2012 Sep 18;75(17):5356-69.
Title:	Interplay between oncogenic K-Ras and wild-type H-Ras in Caco2 cell transformation.
Author:	Ikonomou, Georgia\|Kostourou, Vassiliki\|Shirasawa, Senji\|Sasazuki, Takehiko\|Samiotaki, Martina\|Panayotou, George
PMID:	22800643

1395.
Journal:	J Med Life. 2012 Jun 12;5(2):168-72. Epub 2012 Jun 18.
Title:	Evaluating the treatment of metastatic colorectal cancer with monoclonal antibodies.
Author:	Popa, C\|Ionescu, S\|Mihaila, D\|Gal, I\|Poteca, T\|Simion, S
PMID:	22802884

1396.
Journal:	Histopathology. 2012 Nov;61(5):777-87.
Title:	The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer.
Author:	Zlobec, Inti\|Bihl, Michel P\|Foerster, Anja\|Rufle, Alex\|Lugli, Alessandro
PMID:	22803799

1397.
Journal:	Histopathology. 2012 Dec;61(6):1036-42.
Title:	KRAS mutation is present in a small subset of primary urinary bladder adenocarcinomas.
Author:	Alexander, Riley E\|Lopez-Beltran, Antonio\|Montironi, Rodolfo\|MacLennan, Gregory T\|Post, Kristin M\|Bilbo, Sarah A\|Jones, Timothy D\|Huang, Wenbin\|Rao, Qiu\|Sen, Joyashree D\|Meehan, Kari\|Cornwell, Anita\|Miravalle, Leticia\|Cheng, Liang
PMID:	22804747

1398.
Journal:	BMC Cancer. 2012 Jul 17;12:292.
Title:	Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients.
Author:	Mekenkamp, Leonie J M\|Tol, Jolien\|Dijkstra, Jeroen R\|de Krijger, Inge\|Vink-Borger, M Elisa\|van Vliet, Shannon\|Teerenstra, Steven\|Kamping, Eveline\|Verwiel, Eugene\|Koopman, Miriam\|Meijer, Gerrit A\|van Krieken, J Han Jm\|Kuiper, Roland\|Punt, Cornelis J A\|Nagt
PMID:	22804917

1399.
Journal:	Br J Cancer. 2012 Aug 7;107(4):626-31.
Title:	KRAS mutation detection by high-resolution melting analysis significantly predicts clinical benefit of cetuximab in metastatic colorectal cancer.
Author:	Malapelle, U\|Carlomagno, C\|Salatiello, M\|De Stefano, A\|De Luca, C\|Bianco, R\|Marciano, R\|Cimminiello, C\|Bellevicine, C\|De Placido, S\|Troncone, G
PMID:	22805329

1400.
Journal:	PLoS One. 2012;7(7):e40671.
Title:	Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.
Author:	Steinestel, Konrad\|Bruderlein, Silke\|Steinestel, Julie\|Markl, Bruno\|Schwerer, Michael J\|Arndt, Annette\|Kraft, Klaus\|Propper, Christian\|Moller, Peter
PMID:	22808230

1401.
Journal:	Dis Colon Rectum. 2012 Aug;55(8):913-23.
Title:	Is K-ras gene mutation a prognostic factor for colorectal cancer: a systematic review and meta-analysis.
Author:	Ren, JiaoJiao\|Li, GuangXiao\|Ge, Jie\|Li, Xia\|Zhao, YaShuang
PMID:	22810479

1402.
Journal:	Nature. 2012 Jul 18;487(7407):330-7.
Title:	Comprehensive molecular characterization of human colon and rectal cancer.
Author:
PMID:	22810696

1403.
Journal:	PLoS One. 2012;7(7):e41343.
Title:	BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner.
Author:	Lau, Ken S\|Zhang, Tinghu\|Kendall, Krystle R\|Lauffenburger, Douglas\|Gray, Nathanael S\|Haigis, Kevin M
PMID:	22815993

1404.
Journal:	Clin Cancer Res. 2012 Oct 1;18(19):5314-28.
Title:	Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer.
Author:	Julien, Sylvia\|Merino-Trigo, Ana\|Lacroix, Ludovic\|Pocard, Marc\|Goere, Diane\|Mariani, Pascale\|Landron, Sophie\|Bigot, Ludovic\|Nemati, Fariba\|Dartigues, Peggy\|Weiswald, Louis-Bastien\|Lantuas, Denis\|Morgand, Loic\|Pham, Emmanuel\|Gonin, Patrick\|Dangles-Marie, V
PMID:	22825584

1405.
Journal:	J Cell Biol. 2012 Jul 23;198(2):185-94.
Title:	K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc.
Author:	Magudia, Kirti\|Lahoz, Aurelia\|Hall, Alan
PMID:	22826122

1406.
Journal:	Surgery. 2012 Aug;152(2):277-85.
Title:	Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer.
Author:	Valentino, Joseph D\|Elliott, Victoria A\|Zaytseva, Yekaterina Y\|Rychahou, Piotr G\|Mustain, W Conan\|Wang, Chi\|Gao, Tianyan\|Evers, B Mark
PMID:	22828149

1407.
Journal:	Mol Cancer. 2012 Jul 25;11:46.
Title:	Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model.
Author:	Tsunoda, Toshiyuki\|Ota, Takeharu\|Fujimoto, Takahiro\|Doi, Keiko\|Tanaka, Yoko\|Yoshida, Yasuhiro\|Ogawa, Masahiro\|Matsuzaki, Hiroshi\|Hamabashiri, Masato\|Tyson, Darren R\|Kuroki, Masahide\|Miyamoto, Shingo\|Shirasawa, Senji
PMID:	22830422

1408.
Journal:	Eur J Cancer. 2012 Dec;48(18):3405-13.
Title:	Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.
Author:	Lochhead, Paul\|Imamura, Yu\|Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Liao, Xiaoyun\|Qian, Zhi Rong\|Nishihara, Reiko\|Wu, Kana\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	22840368

1409.
Journal:	Expert Rev Mol Diagn. 2012 Jul;12(6):593-602.
Title:	Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.
Author:	Ong, Frank S\|Das, Kingshuk\|Wang, Jay\|Vakil, Hana\|Kuo, Jane Z\|Blackwell, Wendell-Lamar B\|Lim, Stephen W\|Goodarzi, Mark O\|Bernstein, Kenneth E\|Rotter, Jerome I\|Grody, Wayne W
PMID:	22845480

1410.
Journal:	Cytopathology. 2012 Oct;23(5):286-94.
Title:	Molecular diagnosis on tissues and cells: how it affects training and will affect practice in the future.
Author:	Boyd, C\|Boyle, D P
PMID:	22846108

1411.
Journal:	Clin Transl Oncol. 2012 Oct;14(10):726-39.
Title:	Guidelines for biomarker testing in colorectal carcinoma (CRC): a national consensus of the Spanish Society of Pathology (SEAP) and the Spanish Society of Medical Oncology (SEOM).
Author:	Garcia-Alfonso, Pilar\|Salazar, Ramon\|Garcia-Foncillas, Jesus\|Musulen, Eva\|Garcia-Carbonero, Rocio\|Paya, Artemio\|Perez-Segura, Pedro\|Ramon y Cajal, Santiago\|Navarro, Samuel
PMID:	22855150

1412.
Journal:	Pathol Biol (Paris). 2012 Aug;60(4):223-8.
Title:	[Therapeutic monoclonal antibodies in oncology].
Author:	Bouzid, K\|Bedairia, N\|Marty, M
PMID:	22863361

1413.
Journal:	Clin Transl Oncol. 2012 Dec;14(12):937-42.
Title:	Study of KRAS new predictive marker in a clinical laboratory.
Author:	Bando, Inmaculada\|Cillero, Lourdes\|Sanz-Ortega, Julian\|Llovet, Patricia\|Pescador, Paula\|Ferrer, Milagros\|de la Hoya, Miguel\|Sastre, Javier\|Garcia, Eduardo Diaz-Rubio\|Caldes, Trinidad
PMID:	22865324

1414.
Journal:	Oncotarget. 2012 Jul;3(7):700-8.
Title:	The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes.
Author:	Singhal, Ruchi\|Kandel, Eugene S
PMID:	22869096

1415.
Journal:	J Clin Pathol. 2012 Oct;65(10):940-4. Epub 2012 Aug 7.
Title:	Sanger sequencing in routine KRAS testing: a review of 1720 cases from a pathologist's perspective.
Author:	Malapelle, Umberto\|Bellevicine, Claudio\|Salatiello, Maria\|de Luca, Caterina\|Rispo, Elisabetta\|Riccio, Palmira\|Sparano, Lucianna\|De Stefano, Alfonso\|Carlomagno, Chiara\|Maiello, Francesco Maria\|Vita, Giulia\|Nappi, Oscar\|Troncone, Giancarlo
PMID:	22872705

1416.
Journal:	BMC Cancer. 2012 Aug 9;12:347.
Title:	Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer.
Author:	Kim, Mi-Jung\|Lee, Hye Seung\|Kim, Jee Hyun\|Kim, Yu Jung\|Kwon, Ji Hyun\|Lee, Jeong-Ok\|Bang, Soo-Mee\|Park, Kyoung Un\|Kim, Duck-Woo\|Kang, Sung-Bum\|Kim, Jae-Sung\|Lee, Jong Seok\|Lee, Keun-Wook
PMID:	22876814

1417.
Journal:	BMC Cancer. 2012 Aug 9;12:349.
Title:	Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group.
Author:	Reinacher-Schick, Anke\|Schulmann, Karsten\|Modest, Dominik P\|Bruns, Nina\|Graeven, Ulrich\|Jaworska, Malgorzata\|Greil, Richard\|Porschen, Rainer\|Arnold, Dirk\|Schmiegel, Wolff\|Tannapfel, Andrea
PMID:	22876876

1418.
Journal:	Histopathology. 2012 Dec;61(6):1117-24.
Title:	The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer.
Author:	Fadhil, Wakkas\|Ibrahem, Salih\|Seth, Rashmi\|AbuAli, Ghada\|Ragunath, Krishna\|Kaye, Philip\|Ilyas, Mohammad
PMID:	22882224

1419.
Journal:	Pathol Res Pract. 2012 Oct 15;208(10):592-7.
Title:	Influence of anatomical subsite on the incidence of microsatellite instability, and KRAS and BRAF mutation rates in patients with colon carcinoma.
Author:	Benedix, Frank\|Meyer, Frank\|Kube, Rainer\|Kropf, Siegfried\|Kuester, Doerthe\|Lippert, Hans\|Roessner, Albert\|Kruger, Sabine
PMID:	22898351

1420.
Journal:	Gan To Kagaku Ryoho. 2012 Aug;39(8):1221-5.
Title:	[Evaluation of skin toxicity caused by cetuximab related to its clinical response].
Author:	Osuga, Takahiro\|Kogawa, Takahiro\|Kimura, Tomohiro\|Abe, Masakazu\|Tsuji, Yasushi\|Kondo, Hitoshi
PMID:	22902446

1421.
Journal:	Gan To Kagaku Ryoho. 2012 Aug;39(8):1267-70.
Title:	[A case of colon cancer with chronic renal dysfunction responding to effective retreatment with FOLFIRI].
Author:	Kitade, Hironori\|Shimasaki, Takeo\|Yoshimitsu, Yutaka\|Okuda, Miho\|Hokkoku, Kengo\|Mori, Mitsue\|Shintaku, Kimiko\|Sakuma, Hiroshi\|Ueda, Hiroshi\|Nakai, Masuo
PMID:	22902456

1422.
Journal:	Cancer Biol Ther. 2012 Nov;13(13):1235-43.
Title:	K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecan- or oxaliplatin-based chemotherapy.
Author:	Stec, Rafal\|Bodnar, Lubomir\|Charkiewicz, Radoslaw\|Korniluk, Jan\|Rokita, Marta\|Smoter, Marta\|Ciechowicz, Marzena\|Chyczewski, Lech\|Niklinski, Jacek\|Kozlowski, Wojciech\|Szczylik, Cezary
PMID:	22909976

1423.
Journal:	PLoS One. 2012;7(7):e41347.
Title:	Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.
Author:	Brandi, Giovanni\|Tavolari, Simona\|De Rosa, Francesco\|Di Girolamo, Stefania\|Agostini, Valentina\|Barbera, Maria Aurelia\|Frega, Giorgio\|Biasco, Guido
PMID:	22911782

1424.
Journal:	Oncol Rep. 2012 Nov;28(5):1579-84.
Title:	The prognostic value of KRAS mutations in patients with colorectal cancer.
Author:	Inoue, Yasuhiro\|Saigusa, Susumu\|Iwata, Takashi\|Okugawa, Yoshinaga\|Toiyama, Yuji\|Tanaka, Koji\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22922794

1425.
Journal:	J Transl Med. 2012 Aug 27;10:173.
Title:	Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing.
Author:	Bihl, Michel P\|Foerster, Anja\|Lugli, Alessandro\|Zlobec, Inti
PMID:	22925370

1426.
Journal:	Stud Health Technol Inform. 2012;179:143-54.
Title:	Digital pathology in personalized cancer therapy.
Author:	Slodkowska, Janina\|Garcia-Rojo, Marcial
PMID:	22925795

1427.
Journal:	Genes Chromosomes Cancer. 2012 Dec;51(12):1133-43.
Title:	Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors.
Author:	Poeta, Maria Luana\|Massi, Emanuela\|Parrella, Paola\|Pellegrini, Pasquale\|De Robertis, Mariangela\|Copetti, Massimiliano\|Rabitti, Carla\|Perrone, Giuseppe\|Muda, Andrea Onetti\|Molinari, Francesca\|Zanellato, Elena\|Crippa, Stefano\|Caputo, Damiano\|Caricato, Marco
PMID:	22927297

1428.
Journal:	J Transl Med. 2012 Aug 29;10:178.
Title:	Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia.
Author:	Palomba, Grazia\|Colombino, Maria\|Contu, Antonio\|Massidda, Bruno\|Baldino, Giovanni\|Pazzola, Antonio\|Ionta, MariaTeresa\|Capelli, Francesca\|Trova, Vittorio\|Sedda, Tito\|Sanna, Giovanni\|Tanda, Francesco\|Budroni, Mario\|Palmieri, Giuseppe\|Cossu, Antonio\|Contu, M
PMID:	22931052

1429.
Journal:	Arch Pathol Lab Med. 2012 Sep;136(9):983-92.
Title:	High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.
Author:	Ney, Jasmin Teresa\|Froehner, Stefanie\|Roesler, Angelika\|Buettner, Reinhard\|Merkelbach-Bruse, Sabine
PMID:	22938585

1430.
Journal:	Mol Cancer Ther. 2012 Nov;11(11):2342-51.
Title:	Inhibition of monocarboxylate transporter 2 induces senescence-associated mitochondrial dysfunction and suppresses progression of colorectal malignancies in vivo.
Author:	Lee, Inkyoung\|Lee, Sook-Ja\|Kang, Won Ki\|Park, Chaehwa
PMID:	22964484

1431.
Journal:	Exp Ther Med. 2012 Mar;3(3):547-549.
Title:	Possibility of molecular targeting therapy for the treatment of cancer of unknown primary origin by analysis of intracellular signaling molecules.
Author:	Ohta, Shoichiro\|Cho, Yukiko\|Shibata, Masaharu\|Nagai, Kimihiro\|Iijima, Tatsuo\|Saito, Hitoaki\|Asakura, Hirotaka\|Kojima, Hiroshi
PMID:	22969927

1432.
Journal:	J Int Med Res. 2012;40(4):1589-98.
Title:	Detection of KRAS mutations and their associations with clinicopathological features and survival in Chinese colorectal cancer patients.
Author:	Li, Z\|Chen, Y\|Wang, D\|Wang, G\|He, L\|Suo, J
PMID:	22971512

1433.
Journal:	Cancer Cell. 2012 Sep 11;22(3):318-30.
Title:	EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Author:	Navas, Carolina\|Hernandez-Porras, Isabel\|Schuhmacher, Alberto J\|Sibilia, Maria\|Guerra, Carmen\|Barbacid, Mariano
PMID:	22975375

1434.
Journal:	Ann Oncol. 2012 Sep;23 Suppl 10:x63-70.
Title:	What can molecular pathology offer for optimal decision making?
Author:	Aust, D E\|Sommer, U\|Baretton, G B
PMID:	22987994

1435.
Journal:	Am J Pathol. 2012 Nov;181(5):1847-61.
Title:	Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.
Author:	Yamamoto, Eiichiro\|Suzuki, Hiromu\|Yamano, Hiro-o\|Maruyama, Reo\|Nojima, Masanori\|Kamimae, Seiko\|Sawada, Takeshi\|Ashida, Masami\|Yoshikawa, Kenjiro\|Kimura, Tomoaki\|Takagi, Ryo\|Harada, Taku\|Suzuki, Ryo\|Sato, Akiko\|Kai, Masahiro\|Sasaki, Yasushi\|Tokino, Takashi
PMID:	22995252

1436.
Journal:	Genet Test Mol Biomarkers. 2012 Nov;16(11):1277-81.
Title:	beta-catenin and K-ras mutations and RASSF1A promoter methylation in Taiwanese colorectal cancer patients.
Author:	Chen, Shee-Ping\|Wu, Chang-Chieh\|Huang, Sung-Ying\|Kang, Jung-Cheng\|Chiu, Sheng-Chun\|Yang, Kuo-Liang\|Pang, Cheng-Yoong
PMID:	23009572

1437.
Journal:	Br J Cancer. 2012 Nov 6;107(10):1791-2; author reply 1793-4.
Title:	Comment on 'a comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens'.
Author:	Normanno, N\|Rachiglio, A\|Roma, C\|Ciardiello, F\|Pinto, C
PMID:	23011482

1438.
Journal:	Lancet Oncol. 2012 Nov;13(11):1152-60.
Title:	Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial.
Author:	Foxtrot Collaborative Group
PMID:	23017669

1439.
Journal:	Br J Surg. 2012 Nov;99(11):1575-82.
Title:	KRAS status and outcome of liver resection after neoadjuvant chemotherapy including bevacizumab.
Author:	Stremitzer, S\|Stift, J\|Gruenberger, B\|Tamandl, D\|Aschacher, T\|Wolf, B\|Wrba, F\|Gruenberger, T
PMID:	23027075

1440.
Journal:	Carcinogenesis. 2012 Dec;33(12):2398-408.
Title:	MAP kinase genes and colon and rectal cancer.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Wolff, Roger K
PMID:	23027623

1441.
Journal:	Clin Exp Gastroenterol. 2012;5:167-71.
Title:	Retrospective analysis of KRAS status in metastatic colorectal cancer patients: a single-center feasibility study.
Author:	Montomoli, Jonathan\|Hamilton-Dutoit, Stephen Jacques\|Froslev, Trine\|Taylor, Aliki\|Erichsen, Rune
PMID:	23028236

1442.
Journal:	PLoS One. 2012;7(9):e45462.
Title:	Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.
Author:	Kaler, Pawan\|Augenlicht, Leonard\|Klampfer, Lidija
PMID:	23029025

1443.
Journal:	J BUON. 2012 Jul-Sep;17(3):575-80.
Title:	KRAS and BRAF mutations in Serbian patients with colorectal cancer.
Author:	Jakovljevic, K\|Malisic, E\|Cavic, M\|Krivokuca, A\|Dobricic, J\|Jankovic, R
PMID:	23033302

1444.
Journal:	Clin Cancer Res. 2012 Dec 1;18(23):6531-41.
Title:	Mutation profiling and microsatellite instability in stage II and III colon cancer: an assessment of their prognostic and oxaliplatin predictive value.
Author:	Gavin, Patrick G\|Colangelo, Linda H\|Fumagalli, Debora\|Tanaka, Noriko\|Remillard, Matthew Y\|Yothers, Greg\|Kim, Chungyeul\|Taniyama, Yusuke\|Kim, Seung Il\|Choi, Hyun Joo\|Blackmon, Nicole L\|Lipchik, Corey\|Petrelli, Nicholas J\|O'Connell, Michael J\|Wolmark, Norma
PMID:	23045248

1445.
Journal:	Oncotarget. 2012 Oct;3(10):1182-93.
Title:	Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.
Author:	Kriegl, Lydia\|Vieth, Michael\|Kirchner, Thomas\|Menssen, Antje
PMID:	23045412

1446.
Journal:	Cancer Biol Ther. 2012 Dec;13(14):1390-5.
Title:	A LIN28B polymorphism predicts for colon cancer survival.
Author:	Ye, Yuanqing\|Madison, Blair\|Wu, Xifeng\|Rustgi, Anil K
PMID:	23052130

1447.
Journal:	Clin Exp Metastasis. 2012 Oct;29(7):821-39.
Title:	Meeting the biologic challenge of colorectal metastases.
Author:	Wanebo, Harold J\|LeGolvan, Mark\|Paty, Philip B\|Saha, Sukamal\|Zuber, Markus\|D'Angelica, Michael I\|Kemeny, Nancey E
PMID:	23053740

1448.
Journal:	Onco Targets Ther. 2012;5:199-211.
Title:	Critical appraisal of bevacizumab in the treatment of metastatic colorectal cancer.
Author:	Zoratto, Federica\|Rossi, Luigi\|Zullo, Angelo\|Papa, Anselmo\|Zaccarelli, Eleonora\|Tomao, Luigi\|Giordani, Erika\|Colonna, Maria\|Baiano, Giovanni\|Tomao, Silverio
PMID:	23055745

1449.
Journal:	Anticancer Res. 2012 Oct;32(10):4371-4.
Title:	FBN2 methylation is detected in the serum of colorectal cancer patients with hepatic metastasis.
Author:	Hibi, Kenji\|Mizukami, Hiroki\|Saito, Mitsuo\|Kigawa, Gaku\|Nemoto, Hiroshi\|Sanada, Yutaka
PMID:	23060561

1450.
Journal:	Exp Ther Med. 2012 Jul;4(1):109-112.
Title:	Potential clinical significance of plasma-based KRAS mutation analysis using the COLD-PCR/TaqMan((R)) -MGB probe genotyping method.
Author:	Liu, Peijia\|Liang, Hongyan\|Xue, Li\|Yang, Chun\|Liu, Yang\|Zhou, Kun\|Jiang, Xiaofeng
PMID:	23060932

1451.
Journal:	Nutr Cancer. 2012;64(7):899-910.
Title:	Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
Author:	Razzak, Anthony A\|Oxentenko, Amy S\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Harnack, Lisa J\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Th
PMID:	23061900

1452.
Journal:	Bioorg Med Chem. 2012 Nov 15;20(22):6724-31.
Title:	Synthesis and evaluation of apoptosis induction of thienopyrimidine compounds on KRAS and BRAF mutated colorectal cancer cell lines.
Author:	Pedeboscq, Stephane\|Gravier, Denis\|Casadebaig, Francoise\|Hou, Genevieve\|Gissot, Arnaud\|Rey, Christophe\|Ichas, Francois\|De Giorgi, Francesca\|Lartigue, Lydia\|Pometan, Jean-Paul
PMID:	23063521

1453.
Journal:	Gan To Kagaku Ryoho. 2012 Oct;39(10):1567-70.
Title:	[Two cases of metastatic colorectal cancer in wild-type K-RAS effectively treated by panitumumab].
Author:	Ishiyama, Yasuhiro\|Kotake, Masanori\|Matsunaga, Masashi\|Kitamura, Hirotaka\|Yamamoto, Michihiro\|Inaki, Noriyuki\|Kurokawa, Masaru\|Bando, Hiroyuki\|Yamada, Tetsuji
PMID:	23064074

1454.
Journal:	World J Gastroenterol. 2012 Oct 7;18(37):5171-80.
Title:	KRAS mutation testing in metastatic colorectal cancer.
Author:	Tan, Cong\|Du, Xiang
PMID:	23066310

1455.
Journal:	Jpn J Clin Oncol. 2012 Dec;42(12):1146-51.
Title:	Clinical outcome of Japanese metastatic colorectal cancer patients harbouring the KRAS p.G13D mutation treated with cetuximab + irinotecan.
Author:	Bando, Hideaki\|Yoshino, Takayuki\|Yuki, Satoshi\|Shinozaki, Eiji\|Nishina, Tomohiro\|Kadowaki, Shigenori\|Yamazaki, Kentaro\|Kajiura, Shinya\|Tsuchihara, Katsuya\|Fujii, Satoshi\|Yamanaka, Takeharu\|Ohtsu, Atsushi
PMID:	23071293

1456.
Journal:	Cancer Invest. 2012 Dec;30(10):741-7.
Title:	Concordant KRAS mutations in primary and metastatic colorectal cancer tissue specimens: a meta-analysis and systematic review.
Author:	Han, Cheng-Bo\|Li, Fan\|Ma, Jie-Tao\|Zou, Hua-Wei
PMID:	23075074

1457.
Journal:	Radiol Oncol. 2012 Sep;46(3):252-7.
Title:	Cetuximab in preoperative treatment of rectal cancer - term outcome of the XERT trial.
Author:	Velenik, Vaneja\|Ocvirk, Janja\|Oblak, Irena\|Anderluh, Franc
PMID:	23077464

1458.
Journal:	Chemother Res Pract. 2012;2012:198197.
Title:	Antiepidermal growth factor receptor monoclonal antibodies: applications in colorectal cancer.
Author:	Azizi, Efat\|Kittai, Adam\|Kozuch, Peter
PMID:	23091721

1459.
Journal:	N Engl J Med. 2012 Oct 25;367(17):1596-606.
Title:	Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
Author:	Liao, Xiaoyun\|Lochhead, Paul\|Nishihara, Reiko\|Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Imamura, Yu\|Qian, Zhi Rong\|Baba, Yoshifumi\|Shima, Kaori\|Sun, Ruifang\|Nosho, Katsuhiko\|Meyerhardt, Jeffrey A\|Giovannucci, Edward\|Fuchs, Charles S\|Chan, Andrew T\|Ogino
PMID:	23094721

1460.
Journal:	Ann Surg. 2012 Nov;256(5):763-71; discussion 771.
Title:	Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Author:	Nitsche, Ulrich\|Rosenberg, Robert\|Balmert, Alexander\|Schuster, Tibor\|Slotta-Huspenina, Julia\|Herrmann, Pia\|Bader, Franz G\|Friess, Helmut\|Schlag, Peter M\|Stein, Ulrike\|Janssen, Klaus-Peter
PMID:	23095620

1461.
Journal:	Dtsch Med Wochenschr. 2012 Nov;137(45):2327-31.
Title:	[The change of pathology in the era of personalized medicine using the example of discordant KRAS mutational status in metastasized colorectal carcinoma].
Author:	Hekeler, E\|Zoller, W G\|Wiedorn, K H\|Bosse, A
PMID:	23111797

1462.
Journal:	World J Gastroenterol. 2012 Oct 21;18(39):5551-9.
Title:	MUC5AC/beta-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors.
Author:	Nakae, Kosaburo\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Morimoto, Takashi\|Hidaka, Yasuhiro\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	23112547

1463.
Journal:	Eur J Gastroenterol Hepatol. 2012 Dec;24(12):1430-7.
Title:	Colorectal neuroendocrine carcinomas and adenocarcinomas share oncogenic pathways. A clinico-pathologic study of 12 cases.
Author:	Karkouche, Raymond\|Bachet, Jean-Baptiste\|Sandrini, Jeremy\|Mitry, Emmanuel\|Penna, Christophe\|Cote, Jean-Francois\|Blons, Helene\|Penault-Llorca, Frederique\|Rougier, Philippe\|Saint Andre, Jean-Paul\|Emile, Jean-Francois
PMID:	23114745

1464.
Journal:	Chirurgia (Bucur). 2012 Sep-Oct;107(5):555-63.
Title:	Prognostic and predictive factors in colorectal cancer.
Author:	Bolocan, A\|Ion, D\|Ciocan, D N\|Paduraru, D N
PMID:	23116828

1465.
Journal:	Int J Biol Markers. 2012 Dec 27;27(4):e366-74.
Title:	Survey of KRAS, BRAF and PIK3CA mutational status in 209 consecutive Italian colorectal cancer patients.
Author:	Bozzao, Cristina\|Varvara, Dora\|Piglionica, Marilidia\|Bagnulo, Rosanna\|Forte, Giovanna\|Patruno, Margherita\|Russo, Silvana\|Piscitelli, Domenico\|Stella, Alessandro\|Resta, Nicoletta
PMID:	23125007

1466.
Journal:	PLoS One. 2012;7(11):e48803.
Title:	Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.
Author:	Cohen, Gadi\|Lecht, Shimon\|Arien-Zakay, Hadar\|Ettinger, Keren\|Amsalem, Orit\|Oron-Herman, Mor\|Yavin, Eylon\|Prus, Diana\|Benita, Simon\|Nissan, Aviram\|Lazarovici, Philip
PMID:	23144978

1467.
Journal:	J Cancer Epidemiol. 2012;2012:294730.
Title:	Patterns of cancer genetic testing: a randomized survey of Oregon clinicians.
Author:	Cox, Summer L\|Zlot, Amy I\|Silvey, Kerry\|Elliott, Debi\|Horn, Tara\|Johnson, Amber\|Leman, Richard F
PMID:	23150730

1468.
Journal:	Gan To Kagaku Ryoho. 2012 Nov;39(11):1618-25.
Title:	[Predictive biomarkers for anti-EGFR antibodies].
Author:	Bando, Hideaki\|Yoshino, Takayuki
PMID:	23152013

1469.
Journal:	PLoS One. 2012;7(11):e49683.
Title:	Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer.
Author:	Zhao, Hong\|Li, Qinshan\|Wang, Jian\|Su, Xianwei\|Ng, Ka Man\|Qiu, Tian\|Shan, Ling\|Ling, Yun\|Wang, Linfang\|Cai, Jianqiang\|Ying, Jianming
PMID:	23152928

1470.
Journal:	Rozhl Chir. 2012 Aug;91(8):427-32.
Title:	[K-ras mutational status and tumour-infiltrating lymphocytes in human colon cancer: state of the art and future perspectives].
Author:	Kocian, P\|Sedivcova, M\|Drgac, J\|Cerna, K\|Hoch, J\|Kodet, R\|Bartunkova, J\|Spisek, R\|Fialova, A
PMID:	23153426

1471.
Journal:	Oncotarget. 2012 Nov;3(11):1348-55.
Title:	Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.
Author:	Beggs, Andrew D\|Domingo, Enric\|McGregor, Megan\|Presz, Mikael\|Johnstone, Elaine\|Midgley, Rachel\|Kerr, David\|Oukrif, Dahmane\|Novelli, Marco\|Abulafi, Muti\|Hodgson, Shirley V\|Fadhil, Wakkas\|Ilyas, Mohammad\|Tomlinson, Ian P M
PMID:	23154512

1472.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):579-83.
Title:	[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases].
Author:	Gao, Jing\|Sun, Zhi-wei\|Li, Yan-yan\|Shen, Lin
PMID:	23157823

1473.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):584-9.
Title:	[KRAS and BRAF gene mutations in correlation with clinicopathologic features of colorectal carcinoma in Chinese].
Author:	Zhu, Xiao-li\|Cai, Xu\|Zhang, Ling\|Yang, Fei\|Sheng, Wei-qi\|Lu, Yong-ming\|Du, Xiang\|Zhou, Xiao-yan
PMID:	23157824

1474.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):590-4.
Title:	[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].
Author:	Ling, Yun\|Ying, Jian-ming\|Qiu, Tian\|Shan, Ling\|Guo, Lei\|Lu, Ning
PMID:	23157825

1475.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):595-8.
Title:	[Correlation between KRAS mutations and clinicopathologic features in colorectal carcinomas].
Author:	Gao, Jie\|Zhang, Jing\|Lu, Tao\|Li, Xiao-yuan\|Jia, Ning\|Liang, Zhi-yong
PMID:	23157826

1476.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):599-602.
Title:	[Comparison of real-time PCR-optimized oligonucleotide probe method and Sanger sequencing for detection of KRAS mutations in colorectal and lung carcinomas].
Author:	Qiu, Tian\|Ling, Yun\|Chen, Zhao\|Shan, Ling\|Guo, Lei\|Lu, Ning\|Ying, Jian-ming
PMID:	23157827

1477.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):603-6.
Title:	[Correlation of KRAS gene mutations and clinicopathologic parameters in colorectal carcinoma].
Author:	Wang, Qiong\|Zhong, Mei\|Lu, Ya-li\|Yuan, Jing\|Wei, Li-xin
PMID:	23157828

1478.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):635-6.
Title:	[Consensus for KRAS gene mutation detection in colorectal carcinoma].
Author:
PMID:	23157836

1479.
Journal:	Pol J Pathol. 2012 Nov;63(3):145-64.
Title:	KRAS mutation testing in colorectal cancer as an example of the pathologist's role in personalized targeted therapy: a practical approach.
Author:	Domagala, Pawel\|Hybiak, Jolanta\|Sulzyc-Bielicka, Violetta\|Cybulski, Cezary\|Rys, Janusz\|Domagala, Wenancjusz
PMID:	23161231

1480.
Journal:	BMC Cancer. 2012 Nov 20;12:534.
Title:	Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab.
Author:	Kjersem, Janne B\|Ikdahl, Tone\|Guren, Tormod\|Skovlund, Eva\|Sorbye, Halfdan\|Hamfjord, Julian\|Pfeiffer, Per\|Glimelius, Bengt\|Kersten, Christian\|Solvang, Hiroko\|Tveit, Kjell M\|Kure, Elin H
PMID:	23167843

1481.
Journal:	J Transl Med. 2012 Nov 21;10:232.
Title:	Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome.
Author:	Calemma, Rosa\|Ottaiano, Alessandro\|Trotta, Anna Maria\|Nasti, Guglielmo\|Romano, Carmela\|Napolitano, Maria\|Galati, Domenico\|Borrelli, Pasquale\|Zanotta, Serena\|Cassata, Antonino\|Castello, Giuseppe\|Iaffaioli, Vincenzo Rosario\|Scala, Stefania
PMID:	23171437

1482.
Journal:	Acta Biochim Pol. 2012;59(4):467-74. Epub 2012 Nov 21.
Title:	The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Author:	Tokarz, Paulina\|Blasiak, Janusz
PMID:	23173124

1483.
Journal:	BMC Cancer. 2012 Nov 23;12:548.
Title:	Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer.
Author:	Kristensen, Lasse Sommer\|Kjeldsen, Tina Ellegaard\|Hager, Henrik\|Hansen, Lise Lotte
PMID:	23173730

1484.
Journal:	Int J Mol Sci. 2012 Sep 25;13(10):12153-68.
Title:	Prognostic and predictive roles of KRAS mutation in colorectal cancer.
Author:	Arrington, Amanda K\|Heinrich, Eileen L\|Lee, Wendy\|Duldulao, Marjun\|Patel, Supriya\|Sanchez, Julian\|Garcia-Aguilar, Julio\|Kim, Joseph
PMID:	23202889

1485.
Journal:	Oncol Lett. 2012 Oct;4(4):705-710.
Title:	KRAS mutations and subtyping in colorectal cancer in Jordanian patients.
Author:	Elbjeirami, Wafa M\|Sughayer, Maher A
PMID:	23205087

1486.
Journal:	Acta Cytol. 2012;56(6):655-60.
Title:	Circulating tumor cells in lung cancer.
Author:	Young, Rachel\|Pailler, Emma\|Billiot, Fanny\|Drusch, Francoise\|Barthelemy, Amelie\|Oulhen, Marianne\|Besse, Benjamin\|Soria, Jean-Charles\|Farace, Francoise\|Vielh, Philippe
PMID:	23207444

1487.
Journal:	PLoS One. 2012;7(11):e50701.
Title:	KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells.
Author:	Lin, Yu-Lin\|Liau, Jau-Yu\|Yu, Shan-Chi\|Ou, Da-Liang\|Lin, Liang-In\|Tseng, Li-Hui\|Chang, Yih-Leong\|Yeh, Kun-Huei\|Cheng, Ann-Lii
PMID:	23209813

1488.
Journal:	Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21046-51.
Title:	Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
Author:	Ashraf, Shazad Q\|Nicholls, Angela M\|Wilding, Jennifer L\|Ntouroupi, Triantafyllia G\|Mortensen, Neil J\|Bodmer, Walter F
PMID:	23213241

1489.
Journal:	PLoS One. 2012;7(11):e50806.
Title:	Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer.
Author:	Ree, Anne Hansen\|Kristensen, Annette Torgunrud\|Saelen, Marie Gron\|de Wijn, Rik\|Edvardsen, Hege\|Jovanovic, Jovana\|Abrahamsen, Torveig Weum\|Dueland, Svein\|Flatmark, Kjersti
PMID:	23226389

1490.
Journal:	PLoS One. 2012;7(11):e50925.
Title:	No survival benefit from adding cetuximab or panitumumab to oxaliplatin-based chemotherapy in the first-line treatment of metastatic colorectal cancer in KRAS wild type patients: a meta-analysis.
Author:	Zhou, Si-wei\|Huang, Yuan-yuan\|Wei, Ying\|Jiang, Zhi-min\|Zhang, Yuan-dong\|Yang, Qiong\|Xie, De-rong
PMID:	23226426

1491.
Journal:	Exp Ther Med. 2012 Nov;4(5):790-794.
Title:	Detecting KRAS mutations in peripheral blood of colorectal cancer patients by peptide nucleic acid clamp PCR.
Author:	Miyano, Shozo\|Hanazawa, Kisaburo\|Kitabatake, Toshiaki\|Fujisawa, Minoru\|Kojima, Kuniaki
PMID:	23226727

1492.
Journal:	PLoS One. 2012;7(12):e51449.
Title:	Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells.
Author:	Mologni, Luca\|Brussolo, Stefania\|Ceccon, Monica\|Gambacorti-Passerini, Carlo
PMID:	23227266

1493.
Journal:	Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3659-67.
Title:	Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.
Author:	Weng, Meng-Tzu\|Lee, Jih-Hsiang\|Wei, Shu-Chen\|Li, Qiuning\|Shahamatdar, Sina\|Hsu, Dennis\|Schetter, Aaron J\|Swatkoski, Stephen\|Mannan, Poonam\|Garfield, Susan\|Gucek, Marjan\|Kim, Marianne K H\|Annunziata, Christina M\|Creighton, Chad J\|Emanuele, Michael J\|Harris
PMID:	23236152

1494.
Journal:	Nihon Rinsho. 2012 Dec;70(12):2152-8.
Title:	[Anti-EGFR antibody therapy for colorectal cancer].
Author:	Ishikawa, Toshiaki\|Uetake, Hiroyuki\|Sugihara, Kenichi
PMID:	23259389

1495.
Journal:	Genes Cancer. 2012 Jul;3(7-8):459-66.
Title:	KRAS Testing: A Tool for the Implementation of Personalized Medicine.
Author:	Shackelford, Rodney E\|Whitling, Nicholas A\|McNab, Patricia\|Japa, Shanker\|Coppola, Domenico
PMID:	23264846

1496.
Journal:	PLoS One. 2012;7(12):e51654.
Title:	Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
Author:	Kriegl, Lydia\|Jung, Andreas\|Horst, David\|Rizzani, Antonia\|Jackstadt, Rene\|Hermeking, Heiko\|Gallmeier, Eike\|Gerbes, Alexander L\|Kirchner, Thomas\|Goke, Burkhard\|De Toni, Enrico N
PMID:	23284732

1497.
Journal:	Asian Pac J Cancer Prev. 2012;13(11):5599-603.
Title:	Mutational analysis of key EGFR pathway genes in Chinese breast cancer patients.
Author:	Tong, Lin\|Yang, Xue-Xi\|Liu, Min-Feng\|Yao, Guang-Yu\|Dong, Jian-Yu\|Ye, Chang-Sheng\|Li, Ming
PMID:	23317280

1498.
Journal:	Rinsho Byori. 2012 Oct;60(10):976-81.
Title:	[Genetic and epigenetic changes in colorectal cancer and genetic testing for personalized medicine].
Author:	Suehiro, Yutaka\|Hinoda, Yuji
PMID:	23323463

1499.
Journal:	Front Genet. 2013 Jan 17;3:312.
Title:	High-resolution melting analysis of the common c.1905+1G>A mutation causing dihydropyrimidine dehydrogenase deficiency and lethal 5-fluorouracil toxicity.
Author:	Borras, Emma\|Dotor, Emma\|Arcusa, Angels\|Gamundi, Maria J\|Hernan, Imma\|de Sousa Dias, Miguel\|Mane, Begona\|Agundez, Jose A G\|Blanca, Miguel\|Carballo, Miguel
PMID:	23335937

1500.
Journal:	Acta Chir Iugosl. 2012;59(2):31-8.
Title:	Colorectal carcinoma under microscopy: patohistology or much more?
Author:	Knezevic-Usaj, Slavica\|Zivkovic-Kapicl, Ratjana\|Panjkovic, Milana\|Klem, Istvan\|Eri, Zivka
PMID:	23373356

1501.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Nov;43(6):821-6.
Title:	[A study on the mutation of P53 and K-ras gene in colorectal adenomas and colorectal carcinomas].
Author:	Xu, Wei\|Cheng, Yong\|Shen, Xiong-Fei
PMID:	23387205

1502.
Journal:	Asian Pac J Cancer Prev. 2012;13(12):6097-100.
Title:	ABO and Rh blood groups and risk of colorectal adenocarcinoma.
Author:	Urun, Yuksel\|Ozdemir, Nuriye Yildirim\|Utkan, Gungor\|Akbulut, Hakan\|Savas, Berna\|Oksuzoglu, Berna\|Oztuna, Derya Gokmen\|Dogan, Izzet\|Yalcin, Bulent\|Senler, Filiz Cay\|Onur, Handan\|Demirkazik, Ahmet\|Zengin, Nurullah\|Icli, Fikri
PMID:	23464411

1503.
Journal:	Case Rep Oncol. 2012 May;5(2):404-8.
Title:	Acrometastasis as the Initial Presentation of a KRAS-Positive Colon Cancer.
Author:	Gharwan, Helen\|Yarlagadda, Lavanya\|Duffy, Austin
PMID:	23525126

1504.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Dec;15(12):1318-21.
Title:	[Competing endogenous RNA regulation mechanism and its role in the development and progression of colorectal cancer].
Author:	Gao, Xian-hua\|Fu, Chuan-gang\|Lao, Xin-yuan\|Tan, Zhu-jun
PMID:	23596669

1505.
Journal:	Gastroenterol Hepatol Bed Bench. 2012 Spring;5(2):71-8.
Title:	Molecular profile of colorectal cancer in Indonesia: is there another pathway?
Author:	Abdullah, Murdani\|Sudoyo, Aru Wisaksono\|Utomo, Ahmad R\|Fauzi, Ahmad\|Rani, Abdul Aziz
PMID:	24834203

1506.
Journal:	Am J Clin Oncol. 2013 Feb;36(1):49-52.
Title:	Rechallenge with oxaliplatin and fluoropyrimidine for metastatic colorectal carcinoma after prior therapy.
Author:	Townsend, Amanda R\|Bishnoi, Sarwan\|Broadbridge, Vy\|Beeke, Carol\|Karapetis, Christos S\|Jain, Kunal\|Luke, Colin\|Padbury, Robert\|Price, Timothy J
PMID:	22270106

1507.
Journal:	Oncogene. 2013 Jan 31;32(5):564-76.
Title:	Oncogenic KRAS and BRAF activation of the MEK/ERK signaling pathway promotes expression of dual-specificity phosphatase 4 (DUSP4/MKP2) resulting in nuclear ERK1/2 inhibition.
Author:	Cagnol, S\|Rivard, N
PMID:	22430215

1508.
Journal:	Int J Clin Oncol. 2013 Jun;18(3):454-63.
Title:	Clinical significance of KRAS gene mutation and epidermal growth factor receptor expression in Japanese patients with squamous cell carcinoma of the larynx, oropharynx and hypopharynx.
Author:	Fujii, Satoshi\|Uryu, Hideoki\|Akashi, Ken\|Suzuki, Kensuke\|Yamazaki, Manabu\|Tahara, Makoto\|Hayashi, Ryuichi\|Ochiai, Atsushi
PMID:	22441881

1509.
Journal:	Fundam Clin Pharmacol. 2013 Aug;27(4):434-42.
Title:	Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation.
Author:	Chu, Celine\|Noel-Hudson, Marie-Sophie\|Boige, Valerie\|Goere, Diane\|Marion, Sylvie\|Polrot, Melanie\|Bigot, Ludovic\|Gonin, Patrick\|Farinotti, Robert\|Bonhomme-Faivre, Laurence
PMID:	22458846

1510.
Journal:	Med Princ Pract. 2013;22(1):4-11.
Title:	Tumor markers in clinical practice: a review focusing on common solid cancers.
Author:	Duffy, Michael J
PMID:	22584792

1511.
Journal:	Appl Immunohistochem Mol Morphol. 2013 Jan;21(1):54-8.
Title:	Development of a computerized morphometry application for assessment of the tumor fraction in colon carcinoma tissue samples.
Author:	Hershkovitz, Tova\|Shenhav, Avshalom\|Sabo, Edmond\|Ben-Izhak, Ofer\|Hershkovitz, Dov
PMID:	22595946

1512.
Journal:	Invest New Drugs. 2013 Apr;31(2):345-54.
Title:	Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer.
Author:	Azad, Nilofer\|Dasari, Arvind\|Arcaroli, John\|Taylor, Gretchen E\|Laheru, Daniel A\|Carducci, Michael A\|McManus, Martine\|Quackenbush, Kevin\|Wright, John J\|Hidalgo, Manuel\|Diaz, Luis A Jr\|Donehower, Ross C\|Zhao, Ming\|Rudek, Michelle A\|Messersmith, Wells A
PMID:	22615057

1513.
Journal:	Int J Clin Oncol. 2013 Aug;18(4):670-7.
Title:	Clinical usefulness of KRAS, BRAF, and PIK3CA mutations as predictive markers of cetuximab efficacy in irinotecan- and oxaliplatin-refractory Japanese patients with metastatic colorectal cancer.
Author:	Soeda, Hiroshi\|Shimodaira, Hideki\|Watanabe, Mika\|Suzuki, Takao\|Gamoh, Makio\|Mori, Takahiro\|Komine, Keigo\|Iwama, Noriyuki\|Kato, Shunsuke\|Ishioka, Chikashi
PMID:	22638623

1514.
Journal:	Int J Cancer. 2013 Jan 1;132(1):236-45.
Title:	Prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer patients and its correlation with parameters of the epidermal growth factor receptor signal transduction pathway: results from a randomized trial of the GERMAN AIO CRC Stu
Author:	Stintzing, Sebastian\|Kapaun, Christine\|Laubender, Rudiger Paul\|Jung, Andreas\|Neumann, Jens\|Modest, Dominik Paul\|Giessen, Clemens\|Moosmann, Nicolas\|Wollenberg, Andreas\|Kirchner, Thomas\|Heinemann, Volker
PMID:	22644776

1515.
Journal:	Crit Rev Oncol Hematol. 2013 Jan;85(1):45-81.
Title:	Prognostic and predictive biomarkers for epidermal growth factor receptor-targeted therapy in colorectal cancer: beyond KRAS mutations.
Author:	Custodio, Ana\|Feliu, Jaime
PMID:	22647972

1516.
Journal:	Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):201-7.
Title:	KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials.
Author:	Kim, Sun Young\|Shim, Eun Kyung\|Yeo, Hyun Yang\|Baek, Ji Yeon\|Hong, Yong Sang\|Kim, Dae Yong\|Kim, Tae Won\|Kim, Jee Hyun\|Im, Seock-Ah\|Jung, Kyung Hae\|Chang, Hee Jin
PMID:	22672749

1517.
Journal:	Int J Cancer. 2013 Jan 15;132(2):297-307.
Title:	Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma.
Author:	Conesa-Zamora, Pablo\|Garcia-Solano, Jose\|Garcia-Garcia, Francisco\|Turpin, Maria Del Carmen\|Trujillo-Santos, Javier\|Torres-Moreno, Daniel\|Oviedo-Ramirez, Isabel\|Carbonell-Munoz, Rosa\|Munoz-Delgado, Encarnacion\|Rodriguez-Braun, Edith\|Conesa, Ana\|Perez-Guill
PMID:	22696308

1518.
Journal:	Int J Cancer. 2013 Jan 15;132(2):251-8.
Title:	Colorectal cancer and RASSF family--a special emphasis on RASSF1A.
Author:	Fernandes, Maria Sofia\|Carneiro, Fatima\|Oliveira, Carla\|Seruca, Raquel
PMID:	22733432

1519.
Journal:	Oncogene. 2013 May 16;32(20):2576-85.
Title:	RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets.
Author:	Kent, O A\|Fox-Talbot, K\|Halushka, M K
PMID:	22751122

1520.
Journal:	Int J Colorectal Dis. 2013 May;28(5):733-4.
Title:	Letter to the editor: Worse prognosis caused by anti-EGFR treatment in advanced colorectal cancer patients with KRAS mutation.
Author:	Yin, Peihao\|Qiu, Yanyan\|Li, Qi
PMID:	22752244

1521.
Journal:	Crit Rev Oncol Hematol. 2013 Feb;85(2):121-35.
Title:	Overview of biomarkers in metastatic colorectal cancer: tumour, blood and patient-related factors.
Author:	Clarke, Stephen J\|Karapetis, Christos S\|Gibbs, Peter\|Pavlakis, Nick\|Desai, Jayesh\|Michael, Michael\|Tebbutt, Niall C\|Price, Tim J\|Tabernero, Josep
PMID:	22762963

1522.
Journal:	Cancer. 2013 Jan 15;119(2):266-76.
Title:	Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.
Author:	Miranda, Elena\|Bianchi, Paolo\|Destro, Annarita\|Morenghi, Emanuela\|Malesci, Alberto\|Santoro, Armando\|Laghi, Luigi\|Roncalli, Massimo
PMID:	22786759

1523.
Journal:	Gut. 2013 Apr;62(4):540-9.
Title:	A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction.
Author:	Tian, Sun\|Simon, Iris\|Moreno, Victor\|Roepman, Paul\|Tabernero, Josep\|Snel, Mireille\|van't Veer, Laura\|Salazar, Ramon\|Bernards, Rene\|Capella, Gabriel
PMID:	22798500

1524.
Journal:	Diagn Cytopathol. 2013 Jul;41(7):595-8.
Title:	Epidermal growth factor receptor and Kras gene expression: reliability of mutational analysis on cytological samples.
Author:	Bozzetti, Cecilia\|Negri, Francesca V\|Azzoni, Cinzia\|Naldi, Nadia\|Nizzoli, Rita\|Bortesi, Beatrice\|Zobbi, Valentina\|Bottarelli, Lorena\|Tiseo, Marcello\|Silini, Enrico Maria\|Ardizzoni, Andrea
PMID:	22833420

1525.
Journal:	Cell Res. 2013 Jan;23(1):13-4.
Title:	Resistance to EGFR blockade in colorectal cancer: liquid biopsies and latent subclones.
Author:	Konieczkowski, David J\|Garraway, Levi A
PMID:	22847744

1526.
Journal:	J Pathol. 2013 Jan;229(1):99-110.
Title:	MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes.
Author:	Donehower, Lawrence A\|Creighton, Chad J\|Schultz, Nikolaus\|Shinbrot, Eve\|Chang, Kyle\|Gunaratne, Preethi H\|Muzny, Donna\|Sander, Chris\|Hamilton, Stanley R\|Gibbs, Richard A\|Wheeler, David
PMID:	22899370

1527.
Journal:	Mod Pathol. 2013 Feb;26(2):302-13.
Title:	Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer.
Author:	Voutsina, Alexandra\|Tzardi, Maria\|Kalikaki, Aristea\|Zafeiriou, Zafeiris\|Papadimitraki, Elsa\|Papadakis, Michael\|Mavroudis, Dimitris\|Georgoulias, Vassilis
PMID:	22936063

1528.
Journal:	Ann Surg Oncol. 2013 Apr;20(4):1395-402.
Title:	The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Author:	Takatsuno, Yasushi\|Mimori, Koshi\|Yamamoto, Ken\|Sato, Tetsuya\|Niida, Atsushi\|Inoue, Hiroshi\|Imoto, Seiya\|Kawano, Shuhei\|Yamaguchi, Rui\|Toh, Hiroyuki\|Iinuma, Hisae\|Ishimaru, Shinya\|Ishii, Hideshi\|Suzuki, Sadao\|Tokudome, Shinkan\|Watanabe, Masahiko\|Tanaka, Ju
PMID:	22976378

1529.
Journal:	Exp Mol Pathol. 2013 Feb;94(1):103-8.
Title:	HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53.
Author:	Ghosh, Anil\|Lai, Cecilia\|McDonald, Sarah\|Suraweera, Nirosha\|Sengupta, Neel\|Propper, David\|Dorudi, Sina\|Silver, Andrew
PMID:	22982087

1530.
Journal:	J Cell Biochem. 2013 Mar;114(3):514-24.
Title:	Molecular diagnostics and personalized medicine in oncology: challenges and opportunities.
Author:	Normanno, Nicola\|Rachiglio, Anna Maria\|Roma, Cristin\|Fenizia, Francesca\|Esposito, Claudia\|Pasquale, Raffaella\|La Porta, Maria Libera\|Iannaccone, Alessia\|Micheli, Filippo\|Santangelo, Michele\|Bergantino, Francesca\|Costantini, Susan\|De Luca, Antonella
PMID:	22991232

1531.
Journal:	J Hepatobiliary Pancreat Sci. 2013 Feb;20(2):223-33.
Title:	Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.
Author:	Umeda, Yuzo\|Nagasaka, Takeshi\|Mori, Yoshiko\|Sadamori, Hiroshi\|Sun, Dong-Sheng\|Shinoura, Susumu\|Yoshida, Ryuich\|Satoh, Daisuke\|Nobuoka, Daisuke\|Utsumi, Masashi\|Yoshida, Kazuhiro\|Yagi, Takahito\|Fujiwara, Toshiyoshi
PMID:	23010994

1532.
Journal:	Int J Cancer. 2013 Apr 15;132(8):1800-10.
Title:	Molecular patterns in the evolution of serrated lesion of the colorectum.
Author:	Gaiser, Timo\|Meinhardt, Sandra\|Hirsch, Daniela\|Killian, Jonathan Keith\|Gaedcke, Jochen\|Jo, Peter\|Ponsa, Immaculada\|Miro, Rosa\|Ruschoff, Josef\|Seitz, Gerhard\|Hu, Yue\|Camps, Jordi\|Ried, Thomas
PMID:	23011871

1533.
Journal:	J Cancer Res Clin Oncol. 2013 Feb;139(2):201-9.
Title:	KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines.
Author:	Messner, Isabelle\|Cadeddu, Giuseppe\|Huckenbeck, Wolfgang\|Knowles, Helen J\|Gabbert, Helmut E\|Baldus, Stephan E\|Schaefer, Karl-Ludwig
PMID:	23015072

1534.
Journal:	Neoplasma. 2013;60(1):83-91.
Title:	Bevacizumab in combination with chemotherapy in the first-line treatment of metastatic colorectal carcinoma.
Author:	Usakova, V\|Sevcikova, K\|Usak, J\|Bartosova, Z\|Mikulova, M\|Spanik, S
PMID:	23067221

1535.
Journal:	Genes Chromosomes Cancer. 2013 Feb;52(2):140-9.
Title:	Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization.
Author:	Sawada, Takeshi\|Yamamoto, Eiichiro\|Suzuki, Hiromu\|Nojima, Masanori\|Maruyama, Reo\|Shioi, Yoshihiro\|Akasaka, Risaburo\|Kamimae, Seiko\|Harada, Taku\|Ashida, Masami\|Kai, Masahiro\|Adachi, Yasushi\|Yamamoto, Hiroyuki\|Imai, Kohzoh\|Toyota, Minoru\|Itoh, Fumio\|Sugai,
PMID:	23073979

1536.
Journal:	Methods. 2013 Jan;59(1):116-25.
Title:	RNA biomarkers in colorectal cancer.
Author:	Bustin, Stephen A\|Murphy, Jamie
PMID:	23079397

1537.
Journal:	Clin Colorectal Cancer. 2013 Mar;12(1):28-36.
Title:	Impact of STAT3 phosphorylation on the clinical effectiveness of anti-EGFR-based therapy in patients with metastatic colorectal cancer.
Author:	Dobi, Erion\|Monnien, Franck\|Kim, Stefano\|Ivanaj, Arben\|N'Guyen, Thiery\|Demarchi, Martin\|Adotevi, Olivier\|Thierry-Vuillemin, Antoine\|Jary, Marie\|Kantelip, Bernadette\|Pivot, Xavier\|Godet, Yann\|Degano, Severine Valmary\|Borg, Christophe
PMID:	23083634

1538.
Journal:	J Clin Gastroenterol. 2013 Jul;47(6):509-14.
Title:	KRAS mutations are associated with specific morphologic features in colon cancer.
Author:	Gunal, Armagan\|Hui, Pei\|Kilic, Selim\|Xu, Ruliang\|Jain, Dhanpat\|Mitchell, Kisha\|Robert, Marie\|Kenney, Barton
PMID:	23090042

1539.
Journal:	Dig Dis Sci. 2013 Apr;58(4):998-1003.
Title:	The usability of allele-specific PCR and reverse-hybridization assays for KRAS genotyping in Serbian colorectal cancer patients.
Author:	Brotto, Ksenija\|Malisic, Emina\|Cavic, Milena\|Krivokuca, Ana\|Jankovic, Radmila
PMID:	23108567

1540.
Journal:	Oncogene. 2013 Oct;32(40):4806-13.
Title:	Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression.
Author:	Pagliuca, A\|Valvo, C\|Fabrizi, E\|di Martino, S\|Biffoni, M\|Runci, D\|Forte, S\|De Maria, R\|Ricci-Vitiani, L
PMID:	23128394

1541.
Journal:	Clin Chem. 2013 Jan;59(1):252-60.
Title:	Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.
Author:	Gasch, Christin\|Bauernhofer, Thomas\|Pichler, Martin\|Langer-Freitag, Sabine\|Reeh, Matthias\|Seifert, Adrian M\|Mauermann, Oliver\|Izbicki, Jakob R\|Pantel, Klaus\|Riethdorf, Sabine
PMID:	23136247

1542.
Journal:	Cancer Epidemiol Biomarkers Prev. 2013 Jan;22(1):91-101.
Title:	KRAS testing and epidermal growth factor receptor inhibitor treatment for colorectal cancer in community settings.
Author:	Webster, Jennifer\|Kauffman, Tia L\|Feigelson, Heather Spencer\|Pawloski, Pamala A\|Onitilo, Adedayo A\|Potosky, Arnold L\|Cross, Deanna\|Meier, Paul R\|Mirabedi, Anousheh S\|Delate, Thomas\|Daida, Yihe\|Williams, Andrew E\|Alexander, Gwen L\|McCarty, Catherine A\|Hond
PMID:	23155138

1543.
Journal:	Hum Pathol. 2013 May;44(5):829-36.
Title:	Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Author:	Bettstetter, Marcus\|Berezowska, Sabina\|Keller, Gisela\|Walch, Axel\|Feuchtinger, Annette\|Slotta-Huspenina, Julia\|Feith, Marcus\|Drecoll, Enken\|Hofler, Heinz\|Langer, Rupert
PMID:	23158210

1544.
Journal:	Mol Cell Proteomics. 2013 Feb;12(2):343-55.
Title:	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Author:	Demory Beckler, Michelle\|Higginbotham, James N\|Franklin, Jeffrey L\|Ham, Amy-Joan\|Halvey, Patrick J\|Imasuen, Imade E\|Whitwell, Corbin\|Li, Ming\|Liebler, Daniel C\|Coffey, Robert J
PMID:	23161513

1545.
Journal:	J Pathol. 2013 Feb;229(3):441-8.
Title:	Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.
Author:	Domingo, Enric\|Ramamoorthy, Rajarajan\|Oukrif, Dahmane\|Rosmarin, Daniel\|Presz, Michal\|Wang, Haitao\|Pulker, Hannah\|Lockstone, Helen\|Hveem, Tarjei\|Cranston, Treena\|Danielsen, Havard\|Novelli, Marco\|Davidson, Brian\|Xu, Zheng-Zhou\|Molloy, Peter\|Johnstone, Elain
PMID:	23165447

1546.
Journal:	Br J Cancer. 2013 Jan 15;108(1):115-20.
Title:	KRAS mutational status affects oxaliplatin-based chemotherapy independently from basal mRNA ERCC-1 expression in metastatic colorectal cancer patients.
Author:	Basso, M\|Strippoli, A\|Orlandi, A\|Martini, M\|Calegari, M A\|Schinzari, G\|Di Salvatore, M\|Cenci, T\|Cassano, A\|Larocca, L M\|Barone, C
PMID:	23175150

1547.
Journal:	Int J Clin Oncol. 2013 Dec;18(6):1042-8.
Title:	Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.
Author:	Nakanishi, Ryota\|Harada, Jun\|Tuul, Munkhbold\|Zhao, Yan\|Ando, Koji\|Saeki, Hiroshi\|Oki, Eiji\|Ohga, Takefumi\|Kitao, Hiroyuki\|Kakeji, Yoshihiro\|Maehara, Yoshihiko
PMID:	23188063

1548.
Journal:	J Surg Res. 2013 Mar;180(1):97-103.
Title:	Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis.
Author:	Shetty, Shreya\|Thomas, Peter\|Ramanan, Bala\|Sharma, Poonam\|Govindarajan, Venkatesh\|Loggie, Brian
PMID:	23199549

1549.
Journal:	Am J Surg Pathol. 2013 Mar;37(3):434-42.
Title:	Multiplicity and molecular heterogeneity of colorectal carcinomas in individuals with serrated polyposis.
Author:	Rosty, Christophe\|Walsh, Michael D\|Walters, Rhiannon J\|Clendenning, Mark\|Pearson, Sally-Ann\|Jenkins, Mark A\|Win, Aung Ko\|Hopper, John L\|Sweet, Kevin\|Frankel, Wendy L\|Aronson, Melyssa\|Gallinger, Steve\|Goldblatt, Jack\|Tucker, Kathy\|Greening, Sian\|Gattas, Mi
PMID:	23211288

1550.
Journal:	Yonsei Med J. 2013 Jan 1;54(1):123-30.
Title:	Correlations of dynamic contrast-enhanced magnetic resonance imaging with morphologic, angiogenic, and molecular prognostic factors in rectal cancer.
Author:	Hong, Hye-Suk\|Kim, Se Hoon\|Park, Hae-Jeong\|Park, Mi-Suk\|Kim, Ki Whang\|Kim, Won Ho\|Kim, Nam Kyu\|Lee, Jae Mun\|Cho, Hyeon Je
PMID:	23225808

1551.
Journal:	Mol Cancer Res. 2013 Feb;11(2):109-21.
Title:	Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author:	Tabusa, Hana\|Brooks, Teresa\|Massey, Andrew J
PMID:	23233484

1552.
Journal:	Biochem J. 2013 Mar 1;450(2):285-94.
Title:	The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance.
Author:	Sale, Matthew J\|Cook, Simon J
PMID:	23234544

1553.
Journal:	Virchows Arch. 2013 Jan;462(1):39-46.
Title:	KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance.
Author:	Dijkstra, J R\|Heideman, D A M\|Meijer, G A\|Boers, J E\|'t Hart, N A\|Diebold, J\|Hirschmann, A\|Hoefler, G\|Winter, G\|Miltenberger-Miltenyi, G\|Pereira, S V\|Richman, S D\|Quirke, P\|Rouleau, E L\|Guinebretiere, J M\|Tejpar, S\|Biesmans, B\|van Krieken, J H J M
PMID:	23242173

1554.
Journal:	Oncol Lett. 2013 Jan;5(1):249-254.
Title:	Comparison of KRAS/BRAF mutations between primary tumors and serum in colorectal cancer: Biological and clinical implications.
Author:	Pu, Xingxiang\|Pan, Zhizhong\|Huang, Ying\|Tian, Ying\|Guo, Hongqiang\|Wu, Lin\|He, Xuexing\|Chen, Xinggui\|Zhang, Shaodan\|Lin, Tongyu
PMID:	23255930

1555.
Journal:	Eur J Cancer. 2013 Apr;49(6):1161-8.
Title:	Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: analysis of data from the EXTREME and CRYSTAL studies.
Author:	Licitra, Lisa\|Storkel, Stephan\|Kerr, Keith M\|Van Cutsem, Eric\|Pirker, Robert\|Hirsch, Fred R\|Vermorken, Jan B\|von Heydebreck, Anja\|Esser, Regina\|Celik, Ilhan\|Ciardiello, Fortunato
PMID:	23265711

1556.
Journal:	Mol Biol Rep. 2013 May;40(5):3851-7.
Title:	Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.
Author:	Mokarram, P\|Zamani, M\|Kavousipour, S\|Naghibalhossaini, F\|Irajie, C\|Moradi Sarabi, M\|Hosseini, S V
PMID:	23271133

1557.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S485-91.
Title:	KRAS and BRAF mutations in 203 esophageal squamous cell carcinomas: pyrosequencing technology and literature review.
Author:	Shigaki, Hironobu\|Baba, Yoshifumi\|Watanabe, Masayuki\|Miyake, Keisuke\|Murata, Asuka\|Iwagami, Shiro\|Ishimoto, Takatsugu\|Iwatsuki, Masaaki\|Yoshida, Naoya\|Baba, Hideo
PMID:	23274581

1558.
Journal:	Int J Cancer. 2013 Jul;133(1):43-57.
Title:	Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.
Author:	Basu Roy, Upal K\|Henkhaus, Rebecca S\|Loupakis, Fotios\|Cremolini, Chiara\|Gerner, Eugene W\|Ignatenko, Natalia A
PMID:	23280667

1559.
Journal:	Mol Cancer. 2013 Jan 3;12:1.
Title:	Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Author:	Sengupta, Neel\|Yau, Christopher\|Sakthianandeswaren, Anuratha\|Mouradov, Dmitri\|Gibbs, Peter\|Suraweera, Nirosha\|Cazier, Jean-Baptiste\|Polanco-Echeverry, Guadalupe\|Ghosh, Anil\|Thaha, Mohamed\|Ahmed, Shafi\|Feakins, Roger\|Propper, David\|Dorudi, Sina\|Sieber, Oli
PMID:	23286373

1560.
Journal:	Genet Test Mol Biomarkers. 2013 Feb;17(2):135-9.
Title:	The proto-oncogene KRAS and BRAF profiles and some clinical characteristics in colorectal cancer in the Turkish population.
Author:	Ozen, Filiz\|Ozdemir, Semra\|Zemheri, Ebru\|Hacimuto, Gizem\|Silan, Fatma\|Ozdemir, Ozturk
PMID:	23297805

1561.
Journal:	Cancer Res. 2013 Mar 15;73(6):1912-21.
Title:	Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis.
Author:	Martini, Miriam\|Russo, Mariangela\|Lamba, Simona\|Vitiello, Elisa\|Crowley, Emily Hannah\|Sassi, Francesco\|Romanelli, Davide\|Frattini, Milo\|Marchetti, Antonio\|Bardelli, Alberto
PMID:	23319808

1562.
Journal:	Dis Markers. 2013;34(3):171-7.
Title:	Duplex reverse-hybridization assay for the simultaneous detection of KRAS/BRAF mutations in FFPE-extracted genomic DNA from colorectal cancer specimens.
Author:	Buxhofer-Ausch, Veronika\|Ausch, Christoph\|Zeillinger, Robert\|Oberkanins, Christian\|Dandachi, Nadia\|Reiner-Concin, Angelika\|Kriegshauser, Gernot
PMID:	23324583

1563.
Journal:	Oncology. 2013;84(4):210-3.
Title:	A phase II study of high-dose cetuximab plus irinotecan in colorectal cancer patients with KRAS wild-type tumors who progressed after standard dose of cetuximab plus irinotecan.
Author:	Fora, Ahmad A\|McMahon, Jeanne A\|Wilding, Greg\|Groman, Adrienne\|Ma, Wen Wee\|Romano, Karen S\|Fakih, Marwan G
PMID:	23328486

1564.
Journal:	Histopathology. 2013 Feb;62(3):367-86.
Title:	The serrated pathway to colorectal carcinoma: current concepts and challenges.
Author:	Bettington, Mark\|Walker, Neal\|Clouston, Andrew\|Brown, Ian\|Leggett, Barbara\|Whitehall, Vicki
PMID:	23339363

1565.
Journal:	Aliment Pharmacol Ther. 2013 Mar;37(5):546-54.
Title:	Stool DNA testing for the detection of colorectal neoplasia in patients with inflammatory bowel disease.
Author:	Kisiel, J B\|Yab, T C\|Nazer Hussain, F T\|Taylor, W R\|Garrity-Park, M M\|Sandborn, W J\|Loftus, E V\|Wolff, B G\|Smyrk, T C\|Itzkowitz, S H\|Rubin, D T\|Zou, H\|Mahoney, D W\|Ahlquist, D A
PMID:	23347191

1566.
Journal:	Mod Pathol. 2013 Jun;26(6):825-34.
Title:	Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Walters, Rhiannon J\|Pearson, Sally\|Pavluk, Erika\|Nagler, Belinda\|Pakenas, David\|Jass, Jeremy R\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Parry, Susan\|Hopper, John L\|Giles, Graham G
PMID:	23348904

1567.
Journal:	Eur J Gastroenterol Hepatol. 2013 Mar;25(3):319-26.
Title:	A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations.
Author:	Metz, Andrew J\|Bourke, Michael J\|Moss, Alan\|Dower, Ashraf\|Zarzour, Peter\|Hawkins, Nicholas J\|Ward, Robyn L\|Hesson, Luke B
PMID:	23354161

1568.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jan;16(1):80-3.
Title:	[Application of matrix assisted laser desorption ionization-time of flight-mass spectrometry in detecting K-ras gene mutation of colorectal cancer].
Author:	Xing, Jia-di\|Zhang, Lian-hai\|Li, Jing-jing\|Li, Zi-yu\|Su, Xiang-qian\|Ji, Jia-fu
PMID:	23355247

1569.
Journal:	PLoS One. 2013;8(1):e54510.
Title:	Detection of low-abundance KRAS mutations in colorectal cancer using microfluidic capillary electrophoresis-based restriction fragment length polymorphism method with optimized assay conditions.
Author:	Zhang, Huidan\|Song, Jin\|Ren, Hui\|Xu, Zhangrun\|Wang, Xiaonan\|Shan, Lianfeng\|Fang, Jin
PMID:	23355875

1570.
Journal:	EPMA J. 2013 Jan 28;4(1):3.
Title:	Targeted therapies in colorectal cancer-an integrative view by PPPM.
Author:	Hagan, Suzanne\|Orr, Maria C M\|Doyle, Brendan
PMID:	23356214

1571.
Journal:	Acta Histochem. 2013 Jul;115(6):569-76.
Title:	Two initiation sites of early detection of colon cancer revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of the tumor cells.
Author:	Amsterdam, Abraham\|Shezen, Elias\|Raanan, Calanit\|Schreiber, Letizia\|Slilat, Yasmin\|Fabrikant, Yakov\|Melzer, Ehud\|Seger, Rony
PMID:	23357054

1572.
Journal:	Arch Pathol Lab Med. 2013 Feb;137(2):155.
Title:	Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma.
Author:	Idowu, Michael O
PMID:	23368856

1573.
Journal:	Mod Pathol. 2013 Jul;26(7):1013-22.
Title:	Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status.
Author:	Kim, Jung H\|Rhee, Ye-Y\|Bae, Jeong-M\|Kwon, Hyeong-J\|Cho, Nam-Y\|Kim, Mi J\|Kang, Gyeong H
PMID:	23370766

1574.
Journal:	BMC Cancer. 2013 Feb 2;13:49.
Title:	Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes.
Author:	Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Xanthakis, Ioannis\|Sgouros, Joseph\|Televantou, Despina\|Kafiri, Georgia\|Tsamandas, Athanassios C\|Razis, Evangelia\|Galan
PMID:	23374602

1575.
Journal:	Clin Gastroenterol Hepatol. 2013 Jun;11(6):705-11; quiz e46.
Title:	Clinical subtypes and molecular characteristics of serrated polyposis syndrome.
Author:	Guarinos, Carla\|Sanchez-Fortun, Cristina\|Rodriguez-Soler, Maria\|Perez-Carbonell, Lucia\|Egoavil, Cecilia\|Juarez, Miriam\|Serradesanferm, Anna\|Bujanda, Luis\|Fernandez-Banares, Fernando\|Cubiella, Joaquin\|de-Castro, Luisa\|Guerra, Ana\|Aguirre, Elena\|Herreros-de
PMID:	23376323

1576.
Journal:	J Clin Med Res. 2013 Feb;5(1):67-9.
Title:	A case of syncronised hereditery nonpoliposis colorectal tumor with different hystopathological type and k-ras gene mutation: case report.
Author:	Dinc, Bulent\|Temel, Halis Musfik
PMID:	23390480

1577.
Journal:	BMC Cancer. 2013 Feb 7;13:67.
Title:	A prospective multicenter phase II study evaluating multimodality treatment of patients with peritoneal carcinomatosis arising from appendiceal and colorectal cancer: the COMBATAC trial.
Author:	Glockzin, Gabriel\|Rochon, Justine\|Arnold, Dirk\|Lang, Sven A\|Klebl, Frank\|Zeman, Florian\|Koller, Michael\|Schlitt, Hans J\|Piso, Pompiliu
PMID:	23391248

1578.
Journal:	Target Oncol. 2013 Sep;8(3):183-8.
Title:	Bevacizumab-based treatment in colorectal cancer with a NRAS Q61K mutation.
Author:	Janku, Filip\|Wheler, Jennifer J\|Hong, David S\|Kurzrock, Razelle
PMID:	23400451

1579.
Journal:	Virchows Arch. 2013 Mar;462(3):329-35.
Title:	Comparison of COBAS 4800 KRAS, TaqMan PCR and high resolution melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal carcinomas.
Author:	Harle, Alexandre\|Busser, Benoit\|Rouyer, Marie\|Harter, Valentin\|Genin, Pascal\|Leroux, Agnes\|Merlin, Jean-Louis
PMID:	23400679

1580.
Journal:	Clin Cancer Res. 2013 Jun 1;19(11):2929-40.
Title:	Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.
Author:	Martin, Eric S\|Belmont, Peter J\|Sinnamon, Mark J\|Richard, Larissa Georgeon\|Yuan, Jing\|Coffee, Erin M\|Roper, Jatin\|Lee, Lydia\|Heidari, Pedram\|Lunt, Sophia Y\|Goel, Gautam\|Ji, Xiadong\|Xie, Zhi\|Xie, Tao\|Lamb, John\|Weinrich, Scott L\|VanArsdale, Todd\|Bronson, R
PMID:	23403635

1581.
Journal:	Br J Cancer. 2013 Mar 5;108(4):951-8.
Title:	Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.
Author:	Nishikawa, G\|Sekine, S\|Ogawa, R\|Matsubara, A\|Mori, T\|Taniguchi, H\|Kushima, R\|Hiraoka, N\|Tsuta, K\|Tsuda, H\|Kanai, Y
PMID:	23403822

1582.
Journal:	Int J Cancer. 2013 Sep 1;133(5):1259-65.
Title:	KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Author:	Valtorta, Emanuele\|Misale, Sandra\|Sartore-Bianchi, Andrea\|Nagtegaal, Iris D\|Paraf, Francois\|Lauricella, Calogero\|Dimartino, Valentina\|Hobor, Sebastijan\|Jacobs, Bart\|Ercolani, Cristiana\|Lamba, Simona\|Scala, Elisa\|Veronese, Silvio\|Laurent-Puig, Pierre\|Siena
PMID:	23404247

1583.
Journal:	Br J Cancer. 2013 Mar 5;108(4):771-4.
Title:	Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophagogastric cancer: the AGITG ATTAX2 trial.
Author:	Tebbutt, N C\|Parry, M M\|Zannino, D\|Strickland, A H\|Van Hazel, G A\|Pavlakis, N\|Ganju, V\|Mellor, D\|Dobrovic, A\|Gebski, V J
PMID:	23412099

1584.
Journal:	Cancer Lett. 2013 Jul 10;335(1):225-31.
Title:	Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs.
Author:	Fabbri, Francesco\|Carloni, Silvia\|Zoli, Wainer\|Ulivi, Paola\|Gallerani, Giulia\|Fici, Pietro\|Chiadini, Elisa\|Passardi, Alessandro\|Frassineti, Giovanni L\|Ragazzini, Angela\|Amadori, Dino
PMID:	23419522

1585.
Journal:	Oncol Lett. 2013 Feb;5(2):637-640.
Title:	Bevacizumab-containing regimens after cetuximab failure in Kras wild-type metastatic colorectal carcinoma.
Author:	Lam, Ka On\|Lee, Victor Ho Fun\|Liu, Rico Kin Yin\|Leung, To Wai\|Kwong, Dora Lai Wan
PMID:	23420587

1586.
Journal:	Clin Cancer Res. 2013 Apr 15;19(8):2265-72.
Title:	Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.
Author:	Amatu, Alessio\|Sartore-Bianchi, Andrea\|Moutinho, Catia\|Belotti, Alessandro\|Bencardino, Katia\|Chirico, Giuseppe\|Cassingena, Andrea\|Rusconi, Francesca\|Esposito, Anna\|Nichelatti, Michele\|Esteller, Manel\|Siena, Salvatore
PMID:	23422094

1587.
Journal:	Genet Med. 2013 Jul;15(7):517-27.
Title:	Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy?
Author:
PMID:	23429431

1588.
Journal:	PLoS One. 2013;8(2):e56205.
Title:	EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: a systematic review and meta analysis.
Author:	Jiang, Zheng\|Li, Chunxiang\|Li, Fuyuan\|Wang, Xishan
PMID:	23441167

1589.
Journal:	J Cancer Res Clin Oncol. 2013 Jun;139(6):953-61.
Title:	KRAS allel-specific activity of sunitinib in an isogenic disease model of colorectal cancer.
Author:	Modest, D P\|Camaj, P\|Heinemann, V\|Schwarz, B\|Jung, A\|Laubender, R P\|Gamba, S\|Haertl, C\|Stintzing, S\|Primo, S\|Bruns, C J
PMID:	23455880

1590.
Journal:	Ann Surg Oncol. 2013 Jul;20(7):2166-71.
Title:	Mutations in specific codons of the KRAS oncogene are associated with variable resistance to neoadjuvant chemoradiation therapy in patients with rectal adenocarcinoma.
Author:	Duldulao, Marjun P\|Lee, Wendy\|Nelson, Rebecca A\|Li, Wenyan\|Chen, Zhenbin\|Kim, Joseph\|Garcia-Aguilar, Julio
PMID:	23456389

1591.
Journal:	Int J Mol Sci. 2013 Mar 4;14(3):5170-81.
Title:	EGFR Expression and KRAS and BRAF Mutational Status in Intestinal-Type Sinonasal Adenocarcinoma.
Author:	Szablewski, Vanessa\|Solassol, Jerome\|Poizat, Flora\|Larrieux, Marion\|Crampette, Louis\|Mange, Alain\|Bascoul-Mollevi, Caroline\|Costes, Valerie
PMID:	23459231

1592.
Journal:	Electrophoresis. 2013 May;34(9-10):1415-22.
Title:	Development of a ligase detection reaction/CGE method using a LIF dual-channel detection system for direct identification of allelic composition of mutated DNA in a mixed population of excess wild-type DNA.
Author:	Hamada, Mariko\|Shimase, Koji\|Noda, Keiichi\|Tsukagoshi, Kazuhiko\|Hashimoto, Masahiko
PMID:	23463388

1593.
Journal:	Cancer Res. 2013 May 15;73(10):2965-75.
Title:	Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Author:	Heitzer, Ellen\|Auer, Martina\|Gasch, Christin\|Pichler, Martin\|Ulz, Peter\|Hoffmann, Eva Maria\|Lax, Sigurd\|Waldispuehl-Geigl, Julie\|Mauermann, Oliver\|Lackner, Carolin\|Hofler, Gerald\|Eisner, Florian\|Sill, Heinz\|Samonigg, Hellmut\|Pantel, Klaus\|Riethdorf, Sabin
PMID:	23471846

1594.
Journal:	Eur J Cancer. 2013 Jun;49(9):2126-33.
Title:	The KRAS mutation detection within the initial management of patients with metastatic colorectal cancer: a status report in France in 2011.
Author:	Lievre, A\|Artru, P\|Guiu, M\|Laurent-Puig, P\|Merlin, J L\|Sabourin, J C\|Viguier, J\|Bastie, A\|Seronde, A\|Ducreux, M
PMID:	23473612

1595.
Journal:	Surg Oncol. 2013 Jun;22(2):105-11.
Title:	KRAS mutation does not predict the efficacy of neo-adjuvant chemoradiotherapy in rectal cancer: a systematic review and meta-analysis.
Author:	Clancy, Cillian\|Burke, John P\|Coffey, J Calvin
PMID:	23473635

1596.
Journal:	Int J Cancer. 2013 Aug 15;133(4):984-96.
Title:	Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer.
Author:	Kim, Areumnuri\|Lee, Jung-Eun\|Lee, Seung-Sook\|Kim, Cherin\|Lee, Sun-Joo\|Jang, Won-Suk\|Park, Sunhoo
PMID:	23475782

1597.
Journal:	Jpn J Clin Oncol. 2013 May;43(5):579-82.
Title:	MicroRNAs in Cancer: the 22nd Hiroshima Cancer Seminar/the 4th Japanese Association for RNA Interference Joint International Symposium, 30 August 2012, Grand Prince Hotel Hiroshima.
Author:	Tahara, Hidetoshi\|Kay, Mark A\|Yasui, Wataru\|Tahara, Eiichi
PMID:	23487440

1598.
Journal:	J Egypt Natl Canc Inst. 2013 Mar;25(1):37-41.
Title:	The KRAS StripAssay for detection of KRAS mutation in Egyptian patients with colorectal cancer (CRC): a pilot study.
Author:	Abd El Kader, Yasser\|Emera, Gamal\|Safwat, Ezzat\|Kassem, Heba A\|Kassem, Neemat M
PMID:	23499205

1599.
Journal:	J Egypt Natl Canc Inst. 2013 Mar;25(1):51-6.
Title:	Immunohistochemical assay for detection of K-ras protein expression in metastatic colorectal cancer.
Author:	Elsabah, Mahmoud Tag\|Adel, Iman
PMID:	23499207

1600.
Journal:	Gan To Kagaku Ryoho. 2013 Mar;40(3):397-9.
Title:	[A case of locally advanced sigmoid colon cancer curatively resected after neoadjuvant chemotherapy with FOLFIRI plus panitumumab].
Author:	Horioka, Kohei\|Kaku, Keizo\|Jimi, Sei-ichirou\|Oohata, Yoshihiro\|Kamei, Takafumi
PMID:	23507607

1601.
Journal:	Biomed Res Int. 2013;2013:181384.
Title:	Downregulation of DLC-1 gene by promoter methylation during primary colorectal cancer progression.
Author:	Peng, Haixia\|Long, Feng\|Wu, Zhiyuan\|Chu, Yimin\|Li, Ji\|Kuai, Rong\|Zhang, Jing\|Kang, Zhihua\|Zhang, Xinju\|Guan, Ming
PMID:	23509688

1602.
Journal:	Cancer Treat Rev. 2013 Dec;39(8):908-24.
Title:	Molecular markers to predict outcome to antiangiogenic therapies in colorectal cancer: current evidence and future perspectives.
Author:	Custodio, Ana\|Barriuso, Jorge\|de Castro, Javier\|Martinez-Marin, Virginia\|Moreno, Victor\|Rodriguez-Salas, Nuria\|Feliu, Jaime
PMID:	23510598

1603.
Journal:	Eur J Cancer. 2013 Jul;49(10):2424-32.
Title:	KRAS mutations are associated with inferior clinical outcome in patients with metastatic colorectal cancer, but are not predictive for benefit with cediranib.
Author:	Smith, John C\|Brooks, Laura\|Hoff, Paulo M\|McWalter, Gael\|Dearden, Simon\|Morgan, Shethah R\|Wilson, David\|Robertson, Jane D\|Jurgensmeier, Juliane M
PMID:	23510802

1604.
Journal:	Br J Cancer. 2013 Apr 30;108(8):1757-64.
Title:	KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers.
Author:	Phipps, A I\|Buchanan, D D\|Makar, K W\|Win, A K\|Baron, J A\|Lindor, N M\|Potter, J D\|Newcomb, P A
PMID:	23511557

1605.
Journal:	Br J Cancer. 2013 Apr 16;108(7):1495-501.
Title:	KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: results from a large international multicentre study.
Author:	van Grieken, N C T\|Aoyama, T\|Chambers, P A\|Bottomley, D\|Ward, L C\|Inam, I\|Buffart, T E\|Das, K\|Lim, T\|Pang, B\|Zhang, S L\|Tan, I B\|Carvalho, B\|Heideman, D A M\|Miyagi, Y\|Kameda, Y\|Arai, T\|Meijer, G A\|Tsuburaya, A\|Tan, P\|Yoshikawa, T\|Grabsch, H I
PMID:	23511561

1606.
Journal:	Hum Mutat. 2013 Apr;34(4):636-43.
Title:	Genotyping by induced Forster Resonance Energy Transfer(iFRET) mechanism and simultaneous mutation scanning.
Author:	Masojc, Bartlomiej\|Gorski, Bohdan\|van de Wetering, Thierry\|Debniak, Tadeusz\|Cybulski, Cezary\|Jakubowska, Anna\|Medrek, Krzysztof\|Rudnicka, Helena\|Dwight, Zachary Lawrence\|Lubinski, Jan
PMID:	23520118

1607.
Journal:	PLoS One. 2013;8(3):e58089.
Title:	Utilization of quantitative in vivo pharmacology approaches to assess combination effects of everolimus and irinotecan in mouse xenograft models of colorectal cancer.
Author:	Bradshaw-Pierce, Erica L\|Pitts, Todd M\|Kulikowski, Gillian\|Selby, Heather\|Merz, Andrea L\|Gustafson, Daniel L\|Serkova, Natalie J\|Eckhardt, S Gail\|Weekes, Colin D
PMID:	23520486

1608.
Journal:	Klin Onkol. 2013;26(1):25-30.
Title:	[Molecular biological diagnostics of KRAS and BRAF mutations in patients with colorectal cancer - laboratory experience].
Author:	Robesova, B\|Bajerova, M\|Vasikova, A\|Ostrizkova, L\|Hausnerova, J\|Kyclova, J\|Pospisilova, S\|Mayer, J\|Dvorakova, D
PMID:	23528169

1609.
Journal:	Exp Mol Pathol. 2013 Aug;95(1):74-82.
Title:	Heterogeneity of colorectal cancer (CRC) in reference to KRAS proto-oncogene utilizing WAVE technology.
Author:	Perez, K\|Walsh, R\|Brilliant, K\|Noble, L\|Yakirevich, E\|Breese, V\|Jackson, C\|Chatterjee, D\|Pricolo, V\|Roth, L\|Shah, N\|Cataldo, T\|Safran, H\|Hixson, D\|Quesenberry, P
PMID:	23528430

1610.
Journal:	Expert Opin Med Diagn. 2013 Mar;7(2):137-46.
Title:	Novel biomarkers for the prediction of metastasis in colorectal cancer.
Author:	Zlobec, Inti
PMID:	23530884

1611.
Journal:	J Mol Diagn. 2013 May;15(3):299-311.
Title:	KRAS, BRAF, and TP53 deep sequencing for colorectal carcinoma patient diagnostics.
Author:	Rechsteiner, Markus\|von Teichman, Adriana\|Ruschoff, Jan H\|Fankhauser, Niklaus\|Pestalozzi, Bernhard\|Schraml, Peter\|Weber, Achim\|Wild, Peter\|Zimmermann, Dieter\|Moch, Holger
PMID:	23531339

1612.
Journal:	Asian Pac J Cancer Prev. 2013;14(1):121-6.
Title:	Significance of HPV infection and genic mutation of APC and K-ras in patients with rectal cancer.
Author:	Sun, Zhen-Qiang\|Wang, Hai-Jiang\|Zhao, Ze-Liang\|Wang, Qi-San\|Fan, Chuan-Wen\|Fang, Fa
PMID:	23534709

1613.
Journal:	PLoS One. 2013;8(3):e59939.
Title:	A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.
Author:	Galbiati, Silvia\|Damin, Francesco\|Pinzani, Pamela\|Mancini, Irene\|Vinci, Serena\|Chiari, Marcella\|Orlando, Claudio\|Cremonesi, Laura\|Ferrari, Maurizio
PMID:	23536897

1614.
Journal:	Pathol Res Pract. 2013 Apr;209(4):233-6.
Title:	Mutation analysis of KRAS in primary colorectal cancer and matched metastases by means of highly sensitivity molecular assay.
Author:	Miglio, Umberto\|Mezzapelle, Rosanna\|Paganotti, Alessia\|Allegrini, Sara\|Veggiani, Claudia\|Antona, Jlenia\|Gentilli, Sergio\|Monga, Guido\|Alabiso, Oscar\|Boldorini, Renzo
PMID:	23538047

1615.
Journal:	Cancer Res. 2013 May 15;73(10):3132-44.
Title:	A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Author:	Lau, Ted\|Chan, Emily\|Callow, Marinella\|Waaler, Jo\|Boggs, Jason\|Blake, Robert A\|Magnuson, Steven\|Sambrone, Amy\|Schutten, Melissa\|Firestein, Ron\|Machon, Ondrej\|Korinek, Vladimir\|Choo, Edna\|Diaz, Dolores\|Merchant, Mark\|Polakis, Paul\|Holsworth, Daniel D\|Kraus
PMID:	23539443

1616.
Journal:	J Clin Oncol. 2013 Jun 1;31(16):2016-23.
Title:	Associations between cigarette smoking status and colon cancer prognosis among participants in North Central Cancer Treatment Group Phase III Trial N0147.
Author:	Phipps, Amanda I\|Shi, Qian\|Newcomb, Polly A\|Nelson, Garth D\|Sargent, Daniel J\|Alberts, Steven R\|Limburg, Paul J
PMID:	23547084

1617.
Journal:	Health Technol Assess. 2013 Apr;17(14):1-237.
Title:	The clinical effectiveness and cost-effectiveness of cetuximab (mono- or combination chemotherapy), bevacizumab (combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-lin
Author:	Hoyle, M\|Crathorne, L\|Peters, J\|Jones-Hughes, T\|Cooper, C\|Napier, M\|Tappenden, P\|Hyde, C
PMID:	23547747

1618.
Journal:	BMC Cancer. 2013 Apr 1;13:169.
Title:	High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
Author:	Guedes, Joana G\|Veiga, Isabel\|Rocha, Patricia\|Pinto, Pedro\|Pinto, Carla\|Pinheiro, Manuela\|Peixoto, Ana\|Fragoso, Maria\|Raimundo, Ana\|Ferreira, Paula\|Machado, Manuela\|Sousa, Nuno\|Lopes, Paula\|Araujo, Antonio\|Macedo, Joana\|Alves, Fernando\|Coutinho, Camila\|He
PMID:	23548132

1619.
Journal:	PLoS One. 2013;8(3):e59380.
Title:	The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.
Author:	Allen, Joshua E\|Gallant, Jean-Nicolas\|Dicker, David T\|Amin, Shantu\|Irby, Rosalyn B\|Sharma, Arun K\|El-Deiry, Wafik S
PMID:	23555026

1620.
Journal:	PLoS One. 2013;8(3):e59689.
Title:	Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines.
Author:	Luca, Anna C\|Mersch, Sabrina\|Deenen, Rene\|Schmidt, Stephan\|Messner, Isabelle\|Schafer, Karl-Ludwig\|Baldus, Stephan E\|Huckenbeck, Wolfgang\|Piekorz, Roland P\|Knoefel, Wolfram T\|Krieg, Andreas\|Stoecklein, Nikolas H
PMID:	23555746

1621.
Journal:	Future Oncol. 2013 Apr;9(4):551-60.
Title:	Targeting mechanisms of resistance to anti-EGF receptor therapy in KRAS wild-type colorectal cancer: the path to more personalized medicine.
Author:	Fakih, Marwan
PMID:	23560377

1622.
Journal:	Anticancer Res. 2013 Apr;33(4):1769-72.
Title:	Usefulness of circulating tumor cells after preliminary chemotherapy for prediction of response to further anticancer therapy in patients with initially unresectable metastatic colorectal cancer.
Author:	Neki, Kai\|Kawahara, Hidejiro\|Watanabe, Kazuhiro\|Toyama, Yoichi\|Akiba, Tadashi\|Yanaga, Katsuhiko
PMID:	23564832

1623.
Journal:	Int J Mol Epidemiol Genet. 2013;4(1):1-10. Epub 2013 Mar 18.
Title:	KRAS gene mutations are more common in colorectal villous adenomas and in situ carcinomas than in carcinomas.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	23565319

1624.
Journal:	J Clin Oncol. 2013 Jun 1;31(16):1931-8.
Title:	Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases.
Author:	Ye, Le-Chi\|Liu, Tian-Shu\|Ren, Li\|Wei, Ye\|Zhu, De-Xiang\|Zai, Sheng-Yong\|Ye, Qing-Hai\|Yu, Yiyi\|Xu, Bo\|Qin, Xin-Yu\|Xu, Jianmin
PMID:	23569301

1625.
Journal:	J Cancer. 2013;4(4):320-2.
Title:	Rare Though Not Mutually Exclusive: A Report of Three Cases of Concomitant KRAS and BRAF Mutation and a Review of the Literature.
Author:	Sahin, Ibrahim Halil\|Kazmi, Syed M A\|Yorio, Jeffrey T\|Bhadkamkar, Nishin A\|Kee, Bryan K\|Garrett, Christopher R
PMID:	23569465

1626.
Journal:	Eur J Hum Genet. 2013 Dec;21(12):1383-8.
Title:	Oncogenic mutations and microsatellite instability phenotype predict specific anatomical subsite in colorectal cancer patients.
Author:	Corso, Giovanni\|Pascale, Valeria\|Flauti, Giuseppe\|Ferrara, Francesco\|Marrelli, Daniele\|Roviello, Franco
PMID:	23572025

1627.
Journal:	PLoS One. 2013;8(4):e60142.
Title:	Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.
Author:	Sinha, Rupal\|Hussain, Showket\|Mehrotra, Ravi\|Kumar, R Suresh\|Kumar, Kapil\|Pande, Pankaj\|Doval, Dinesh Chandra\|Basir, Seemi Farhat\|Bharadwaj, Mausumi
PMID:	23573237

1628.
Journal:	Magy Onkol. 2013 Mar;57(1):56-62.
Title:	[Biomarkers in solid tumors].
Author:	Nagy, Zsuzsanna
PMID:	23573523

1629.
Journal:	Cancer Res. 2013 Jun 1;73(11):3248-61.
Title:	Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
Author:	Wang, Grace M\|Wong, Hong Yuen\|Konishi, Hiroyuki\|Blair, Brian G\|Abukhdeir, Abde M\|Gustin, John P\|Rosen, D Marc\|Denmeade, Samuel Ray\|Rasheed, Zeshaan\|Matsui, William\|Garay, Joseph P\|Mohseni, Morassa\|Higgins, Michaela J\|Cidado, Justin\|Jelovac, Danijela\|Croes
PMID:	23580570

1630.
Journal:	J Clin Oncol. 2013 May 20;31(15):1834-41.
Title:	Designing transformative clinical trials in the cancer genome era.
Author:	Sleijfer, Stefan\|Bogaerts, Jan\|Siu, Lillian L
PMID:	23589555

1631.
Journal:	Am J Surg. 2013 May;205(5):608-12; discussion 612.
Title:	Stage III & IV colon and rectal cancers share a similar genetic profile: a review of the Oregon Colorectal Cancer Registry.
Author:	Gawlick, Ute\|Lu, Kim C\|Douthit, Miriam A\|Diggs, Brian S\|Schuff, Kathryn G\|Herzig, Daniel O\|Tsikitis, Vassiliki L
PMID:	23592171

1632.
Journal:	Mol Diagn Ther. 2013 Jun;17(3):193-203.
Title:	KRAS and BRAF mutation analysis in colorectal adenocarcinoma specimens with a low percentage of tumor cells.
Author:	Lewandowska, Marzena Anna\|Jozwicki, Wojciech\|Zurawski, Bogdan
PMID:	23606169

1633.
Journal:	Clin Cancer Res. 2013 Jun 1;19(11):2794-6.
Title:	Mouse models of Kras-mutant colorectal cancer: valuable GEMMs for drug testing?
Author:	Di Nicolantonio, Federica\|Bardelli, Alberto
PMID:	23613316

1634.
Journal:	Cancer Res Treat. 2013 Mar;45(1):55-62.
Title:	Impact of KRAS Mutation Status on Outcomes in Metastatic Colon Cancer Patients without Anti-Epidermal Growth Factor Receptor Therapy.
Author:	Kim, Seung Tae\|Park, Kyong Hwa\|Kim, Jun Suk\|Shin, Sang Won\|Kim, Yeul Hong
PMID:	23613671

1635.
Journal:	BMC Cancer. 2013 Apr 23;13:200.
Title:	Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery.
Author:	Derbel, Olfa\|Wang, Qing\|Desseigne, Francoise\|Rivoire, Michel\|Meeus, Pierre\|Peyrat, Patrice\|Stella, Mattia\|Martel-Lafay, Isabelle\|Lemaistre, Anne-Isabelle\|de La Fouchardiere, Christelle
PMID:	23617638

1636.
Journal:	Br J Cancer. 2013 May 28;108(10):2088-96.
Title:	Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer.
Author:	Koelzer, V H\|Karamitopoulou, E\|Dawson, H\|Kondi-Pafiti, A\|Zlobec, I\|Lugli, A
PMID:	23632477

1637.
Journal:	Clin Cancer Res. 2013 Jun 15;19(12):3285-96.
Title:	PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.
Author:	Day, Fiona L\|Jorissen, Robert N\|Lipton, Lara\|Mouradov, Dmitri\|Sakthianandeswaren, Anuratha\|Christie, Michael\|Li, Shan\|Tsui, Cary\|Tie, Jeannie\|Desai, Jayesh\|Xu, Zheng-Zhou\|Molloy, Peter\|Whitehall, Vicki\|Leggett, Barbara A\|Jones, Ian T\|McLaughlin, Stephen\|W
PMID:	23633456

1638.
Journal:	Discov Med. 2013 Apr;15(83):259-67.
Title:	Personalized cancer treatment and the myth of KRAS wild-type colon tumors.
Author:	Parsons, Barbara L\|Myers, Meagan B
PMID:	23636143

1639.
Journal:	Clin Gastroenterol Hepatol. 2013 Oct;11(10):1313-8.
Title:	Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia.
Author:	Lidgard, Graham P\|Domanico, Michael J\|Bruinsma, Janelle J\|Light, James\|Gagrat, Zubin D\|Oldham-Haltom, Rebecca L\|Fourrier, Keith D\|Allawi, Hatim\|Yab, Tracy C\|Taylor, William R\|Simonson, Julie A\|Devens, Mary\|Heigh, Russell I\|Ahlquist, David A\|Berger, Barry
PMID:	23639600

1640.
Journal:	Mol Biol Rep. 2013 Jun;40(6):4109-14.
Title:	The prevalence and prognostic significance of KRAS mutation in bladder cancer, chronic myeloid leukemia and colorectal cancer.
Author:	Ouerhani, Slah\|Bougatef, Karim\|Soltani, Ismail\|Elgaaied, Amel Ben Ammar\|Abbes, Salem\|Menif, Samia
PMID:	23640097

1641.
Journal:	Anticancer Res. 2013 May;33(5):2129-34.
Title:	KRAS mutations in patients with colorectal cancer as detected by high-resolution melting analysis and direct sequencing.
Author:	Akiyoshi, Kohei\|Yamada, Yasuhide\|Honma, Yoshitaka\|Iwasa, Satoru\|Kato, Ken\|Hamaguchi, Tetsuya\|Shimada, Yasuhiro\|Taniguchi, Hirokazu\|Furuta, Koh
PMID:	23645765

1642.
Journal:	Clin Chem. 2013 Oct;59(10):1447-56.
Title:	Companion biomarkers: paving the pathway to personalized treatment for cancer.
Author:	Duffy, Michael J\|Crown, John
PMID:	23656699

1643.
Journal:	Jpn J Clin Oncol. 2013 Jul;43(7):706-12.
Title:	KRAS mutational status in Japanese patients with colorectal cancer: results from a nationwide, multicenter, cross-sectional study.
Author:	Watanabe, Toshiaki\|Yoshino, Takayuki\|Uetake, Hiroyuki\|Yamazaki, Kentaro\|Ishiguro, Megumi\|Kurokawa, Tatsuo\|Saijo, Nagahiro\|Ohashi, Yasuo\|Sugihara, Kenichi
PMID:	23657052

1644.
Journal:	Int J Surg. 2013;11(7):507-13.
Title:	Cetuximab therapy in the treatment of metastatic colorectal cancer: the future frontier?
Author:	Gomez, D\|De Rosa, A\|Addison, A\|Brooks, A\|Malik, H Z\|Cameron, I C
PMID:	23660586

1645.
Journal:	Br J Cancer. 2013 May 28;108(10):2153-63.
Title:	The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer.
Author:	Eklof, V\|Wikberg, M L\|Edin, S\|Dahlin, A M\|Jonsson, B-A\|Oberg, A\|Rutegard, J\|Palmqvist, R
PMID:	23660947

1646.
Journal:	Gastroenterology. 2013 Aug;145(2):348-56.e1-2.
Title:	Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women.
Author:	Samadder, N Jewel\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Weisenberger, Daniel J\|Laird, Peter W\|Lynch, Charles F\|Anderson, Kristin E\|French, Amy J\|Haile, Robert W\|Potter, John D\|Slager, Susan L\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Cerhan, James
PMID:	23665275

1647.
Journal:	Ann Surg. 2013 Jun;257(6):1089-95.
Title:	MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases.
Author:	Isella, Claudio\|Mellano, Alfredo\|Galimi, Francesco\|Petti, Consalvo\|Capussotti, Lorenzo\|De Simone, Michele\|Bertotti, Andrea\|Medico, Enzo\|Muratore, Andrea
PMID:	23665971

1648.
Journal:	PLoS One. 2013 May 9;8(5):e62989.
Title:	A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection.
Author:	Kitano, Shiro\|Myers, Jamie\|Nakamura, Junko\|Yamane, Akio\|Yamashita, Mami\|Nakayama, Masato\|Tsukahara, Yusuke\|Ushida, Hiroshi\|Liu, Wanqing\|Ratain, Mark J\|Amano, Masahiko
PMID:	23671647

1649.
Journal:	PLoS Med. 2013;10(5):e1001453.
Title:	Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value.
Author:	Marisa, Laetitia\|de Reynies, Aurelien\|Duval, Alex\|Selves, Janick\|Gaub, Marie Pierre\|Vescovo, Laure\|Etienne-Grimaldi, Marie-Christine\|Schiappa, Renaud\|Guenot, Dominique\|Ayadi, Mira\|Kirzin, Sylvain\|Chazal, Maurice\|Flejou, Jean-Francois\|Benchimol, Daniel\|Ber
PMID:	23700391

1650.
Journal:	PLoS One. 2013 May 21;8(5):e64271.
Title:	Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.
Author:	Han, Sae-Won\|Kim, Hwang-Phill\|Shin, Jong-Yeon\|Jeong, Eun-Goo\|Lee, Won-Chul\|Lee, Kyung-Hun\|Won, Jae-Kyung\|Kim, Tae-Yong\|Oh, Do-Youn\|Im, Seock-Ah\|Bang, Yung-Jue\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Seo, Jeong-Sun\|Kim, Jong-Il\|Kim
PMID:	23700467

1651.
Journal:	Am Soc Clin Oncol Educ Book. 2013. pii: 0011300e115.
Title:	Right drug for the right patient: hurdles and the path forward in colorectal cancer.
Author:	Kopetz, Scott
PMID:	23714474

1652.
Journal:	Am Soc Clin Oncol Educ Book. 2013. pii: 0011300200.
Title:	Rare epithelial tumors arising in or near the ovary: a review of the risk factors, presentation, and future treatment direction for ovarian clear cell and mucinous carcinoma.
Author:	Jain, Angela\|Seiden, Michael V
PMID:	23714502

1653.
Journal:	Lancet Oncol. 2013 Jul;14(8):749-59.
Title:	Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trial.
Author:	Seymour, Matthew T\|Brown, Sarah R\|Middleton, Gary\|Maughan, Timothy\|Richman, Susan\|Gwyther, Stephen\|Lowe, Catherine\|Seligmann, Jennifer F\|Wadsley, Jonathan\|Maisey, Nick\|Chau, Ian\|Hill, Mark\|Dawson, Lesley\|Falk, Stephen\|O'Callaghan, Ann\|Benstead, Kim\|Chambe
PMID:	23725851

1654.
Journal:	Int J Colorectal Dis. 2013 Dec;28(12):1637-42.
Title:	Descriptive profile of PIK3CA-mutated colorectal cancer in postmenopausal women.
Author:	Phipps, Amanda I\|Makar, Karen W\|Newcomb, Polly A
PMID:	23728594

1655.
Journal:	Med Oncol. 2013;30(3):617.
Title:	KRAS gene mutations in correlation with clinicopathological features of colorectal carcinomas in Indian patient cohort.
Author:	Patil, Harshali\|Korde, Rajesh\|Kapat, Arnab
PMID:	23729268

1656.
Journal:	Cancer Discov. 2013 Jun;3(6):658-73.
Title:	Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.
Author:	Bardelli, Alberto\|Corso, Simona\|Bertotti, Andrea\|Hobor, Sebastijan\|Valtorta, Emanuele\|Siravegna, Giulia\|Sartore-Bianchi, Andrea\|Scala, Elisa\|Cassingena, Andrea\|Zecchin, Davide\|Apicella, Maria\|Migliardi, Giorgia\|Galimi, Francesco\|Lauricella, Calogero\|Zanon
PMID:	23729478

1657.
Journal:	Transl Oncol. 2013 Jun 1;6(3):319-28. Print 2013 Jun.
Title:	Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load.
Author:	Mouliere, Florent\|El Messaoudi, Safia\|Gongora, Celine\|Guedj, Anne-Sophie\|Robert, Bruno\|Del Rio, Maguy\|Molina, Franck\|Lamy, Pierre-Jean\|Lopez-Crapez, Evelyne\|Mathonnet, Muriel\|Ychou, Marc\|Pezet, Denis\|Thierry, Alain R
PMID:	23730412

1658.
Journal:	J Gastrointest Oncol. 2013 Jun;4(2):182-92.
Title:	Signature of microsatellite instability, KRAS and BRAF gene mutations in German patients with locally advanced rectal adenocarcinoma before and after neoadjuvant 5-FU radiochemotherapy.
Author:	Demes, Melanie\|Scheil-Bertram, Stefanie\|Bartsch, Holger\|Fisseler-Eckhoff, Annette
PMID:	23730514

1659.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4104-13.
Title:	Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/- cetuximab.
Author:	Smith, Christopher G\|Fisher, David\|Claes, Bart\|Maughan, Timothy S\|Idziaszczyk, Shelley\|Peuteman, Gilian\|Harris, Rebecca\|James, Michelle D\|Meade, Angela\|Jasani, Bharat\|Adams, Richard A\|Kenny, Sarah\|Kaplan, Richard\|Lambrechts, Diether\|Cheadle, Jeremy P
PMID:	23741067

1660.
Journal:	Clin Cancer Res. 2013 Jul 15;19(14):3987-95.
Title:	Phase II study of everolimus in patients with metastatic colorectal adenocarcinoma previously treated with bevacizumab-, fluoropyrimidine-, oxaliplatin-, and irinotecan-based regimens.
Author:	Ng, Kimmie\|Tabernero, Josep\|Hwang, Jimmy\|Bajetta, Emilio\|Sharma, Sunil\|Del Prete, Salvatore A\|Arrowsmith, Edward R\|Ryan, David P\|Sedova, Michaela\|Jin, Jin\|Malek, Kamel\|Fuchs, Charles S
PMID:	23743569

1661.
Journal:	Gastrointest Cancer Res. 2013 Mar;6(2):47-55.
Title:	Alternate dosing of cetuximab for patients with metastatic colorectal cancer.
Author:	Hubbard, Joleen M\|Alberts, Steven R
PMID:	23745159

1662.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S527-36.
Title:	Overexpression of hypoxia inducible factor-1 alpha is an independent risk factor for recurrence after curative resection of colorectal liver metastases.
Author:	Shimomura, Manabu\|Hinoi, Takao\|Kuroda, Shintaro\|Adachi, Tomohiro\|Kawaguchi, Yasuo\|Sasada, Tatsunari\|Takakura, Yuji\|Egi, Hiroyuki\|Okajima, Masazumi\|Tashiro, Hirotaka\|Nishizaka, Takashi\|Ohdan, Hideki
PMID:	23748663

1663.
Journal:	Med Oncol. 2013;30(3):620.
Title:	Decreased expression of DUSP4 is associated with liver and lung metastases in colorectal cancer.
Author:	Saigusa, Susumu\|Inoue, Yasuhiro\|Tanaka, Koji\|Toiyama, Yuji\|Okugawa, Yoshinaga\|Shimura, Tadanobu\|Hiro, Junichiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	23749251

1664.
Journal:	Anticancer Res. 2013 Jun;33(6):2499-508.
Title:	Combination of CYP inhibitor with MEK/ERK inhibitor enhances the inhibitory effect on ERK in BRAF mutant colon cancer cells.
Author:	Lim, Sun Min\|Hwang, Jee Won\|Ahn, Joong Bae\|Bae, Soo Kyung\|Park, Chan Hee\|Kim, Ki-Yeol\|Rha, Sun Young\|Chung, Hyun Cheol\|Roh, Jae Kyung\|Shin, Sang Joon
PMID:	23749901

1665.
Journal:	Mol Syst Biol. 2013;9:673.
Title:	Network quantification of EGFR signaling unveils potential for targeted combination therapy.
Author:	Klinger, Bertram\|Sieber, Anja\|Fritsche-Guenther, Raphaela\|Witzel, Franziska\|Berry, Leanne\|Schumacher, Dirk\|Yan, Yibing\|Durek, Pawel\|Merchant, Mark\|Schafer, Reinhold\|Sers, Christine\|Bluthgen, Nils
PMID:	23752269

1666.
Journal:	Clin Colorectal Cancer. 2013 Sep;12(3):214-7.
Title:	Discordance of KRAS mutational status in a single colonic resection specimen in a patient with colorectal cancer: a case report and review of the literature.
Author:	Smaglo, Brandon G\|Marshall, John L
PMID:	23755925

1667.
Journal:	Clin Cancer Res. 2013 Aug 1;19(15):4149-62.
Title:	Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Author:	Spreafico, Anna\|Tentler, John J\|Pitts, Todd M\|Tan, Aik Choon\|Gregory, Mark A\|Arcaroli, John J\|Klauck, Peter J\|McManus, Martine C\|Hansen, Ryan J\|Kim, Jihye\|Micel, Lindsey N\|Selby, Heather M\|Newton, Timothy P\|McPhillips, Kelly L\|Gustafson, Daniel L\|Degregor
PMID:	23757356

1668.
Journal:	Oncol Lett. 2013 May;5(5):1741-1743.
Title:	Coexistence of two different mutations in codon 12 of the Kras gene in colorectal cancer: Report of a case supporting the concept of tumoral heterogeneity.
Author:	Improta, Giuseppina\|Zupa, Angela\|Possidente, Luciana\|Tartarone, Alfredo\|Pedicini, Piernicola\|Nappi, Antonio\|Molinari, Sergio\|Fraggetta, Filippo\|Vita, Giulia
PMID:	23761841

1669.
Journal:	Histopathology. 2013 Aug;63(2):187-93.
Title:	Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma.
Author:	Adackapara, Cheryl A\|Sholl, Lynette M\|Barletta, Justine A\|Hornick, Jason L
PMID:	23763264

1670.
Journal:	Br J Cancer. 2013 Jul 23;109(2):408-15.
Title:	Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.
Author:	Murata, A\|Baba, Y\|Watanabe, M\|Shigaki, H\|Miyake, K\|Ishimoto, T\|Iwatsuki, M\|Iwagami, S\|Sakamoto, Y\|Miyamoto, Y\|Yoshida, N\|Nosho, K\|Baba, H
PMID:	23764749

1671.
Journal:	Clin Colorectal Cancer. 2013 Sep;12(3):168-78.
Title:	Clinical utility of KRAS and BRAF mutations in a cohort of patients with colorectal neoplasms submitted for microsatellite instability testing.
Author:	Cushman-Vokoun, Allison M\|Stover, Daniel G\|Zhao, Zhiguo\|Koehler, Elizabeth A\|Berlin, Jordan D\|Vnencak-Jones, Cindy L
PMID:	23773459

1672.
Journal:	Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11127-32.
Title:	Genetic reconstitution of tumorigenesis in primary intestinal cells.
Author:	Onuma, Kunishige\|Ochiai, Masako\|Orihashi, Kaoru\|Takahashi, Mami\|Imai, Toshio\|Nakagama, Hitoshi\|Hippo, Yoshitaka
PMID:	23776211

1673.
Journal:	PLoS One. 2013 Jun 13;8(6):e65479.
Title:	PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival.
Author:	Rosty, Christophe\|Young, Joanne P\|Walsh, Michael D\|Clendenning, Mark\|Sanderson, Kristy\|Walters, Rhiannon J\|Parry, Susan\|Jenkins, Mark A\|Win, Aung Ko\|Southey, Melissa C\|Hopper, John L\|Giles, Graham G\|Williamson, Elizabeth J\|English, Dallas R\|Buchanan, Dani
PMID:	23785428

1674.
Journal:	Neoplasma. 2013;60(5):561-7.
Title:	Cetuximab plus chemotherapy as first-line treatment for metastatic colorectal cancer: effect of KRAS mutation on treatment efficacy in Taiwanese patients.
Author:	Chen, M C\|Chiang, F F\|Wang, H M
PMID:	23790176

1675.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):711-9.
Title:	FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer.
Author:	Lim, Bora\|Scicchitano, Angelique\|Beachler, Cheryl\|Gusani, Niraj\|Sarwani, Nabeel\|Yang, Zhaohai\|Staveley-O'Carroll, Kevin\|Ashkenazi, Avi\|Portera, Chia\|El-Deiry, Wafik S
PMID:	23792567

1676.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):699-702.
Title:	Contradictory KRAS mutation test results in a patient with metastatic colon cancer: a clinical dilemma in the era of personalized medicine.
Author:	Lamparella, Nicholas E\|Saroya, Bikramajit S\|Yang, Zhaohai\|Sarwani, Nabeel E\|El-Deiry, Wafik S
PMID:	23792572

1677.
Journal:	JAMA. 2013 Jun 26;309(24):2563-71.
Title:	Aspirin use and risk of colorectal cancer according to BRAF mutation status.
Author:	Nishihara, Reiko\|Lochhead, Paul\|Kuchiba, Aya\|Jung, Seungyoun\|Yamauchi, Mai\|Liao, Xiaoyun\|Imamura, Yu\|Qian, Zhi Rong\|Morikawa, Teppei\|Wang, Molin\|Spiegelman, Donna\|Cho, Eunyoung\|Giovannucci, Edward\|Fuchs, Charles S\|Chan, Andrew T\|Ogino, Shuji
PMID:	23800934

1678.
Journal:	Mod Pathol. 2013 Dec;26(12):1642-56.
Title:	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.
Author:	Walsh, Michael D\|Clendenning, Mark\|Williamson, Elizabeth\|Pearson, Sally-Ann\|Walters, Rhiannon J\|Nagler, Belinda\|Packenas, David\|Win, Aung K\|Hopper, John L\|Jenkins, Mark A\|Haydon, Andrew M\|Rosty, Christophe\|English, Dallas R\|Giles, Graham G\|McGuckin, Micha
PMID:	23807779

1679.
Journal:	J Mol Diagn. 2013 Sep;15(5):652-60.
Title:	Similarities of molecular genetic changes in synchronous and metachronous colorectal cancers are limited and related to the cancers' proximities to each other.
Author:	Zauber, Peter\|Huang, Jiaying\|Sabbath-Solitare, Marlene\|Marotta, Stephen
PMID:	23810502

1680.
Journal:	Med Oncol. 2013;30(3):650.
Title:	KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: a pooled analysis of 12 published trials.
Author:	Petrelli, Fausto\|Coinu, Andrea\|Cabiddu, Mary\|Ghilardi, Mara\|Barni, Sandro
PMID:	23828442

1681.
Journal:	Clin Chim Acta. 2013 Oct 21;425:1-2.
Title:	Companion-diagnostic testing limited to KRAS codons 12 and 13 misses 17% of potentially relevant RAS mutations in colorectal cancer.
Author:	Netzel, Brian C\|Grebe, Stefan K G
PMID:	23832066

1682.
Journal:	J Pathol. 2013 Sep;231(1):63-76.
Title:	Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer.
Author:	Budinska, Eva\|Popovici, Vlad\|Tejpar, Sabine\|D'Ario, Giovanni\|Lapique, Nicolas\|Sikora, Katarzyna Otylia\|Di Narzo, Antonio Fabio\|Yan, Pu\|Hodgson, John Graeme\|Weinrich, Scott\|Bosman, Fred\|Roth, Arnaud\|Delorenzi, Mauro
PMID:	23836465

1683.
Journal:	Cancer Biomark. 2013;13(2):89-97.
Title:	Direct sequencing is a reliable assay with good clinical applicability for KRAS mutation testing in colorectal cancer.
Author:	Wang, Jianfei\|Yang, Hongying\|Shen, Yinchen\|Wang, Shuai\|Lin, Dongmei\|Ma, Li\|Han, Xiaohong\|Shi, Yuankai
PMID:	23838137

1684.
Journal:	Pathol Biol (Paris). 2013 Dec;61(6):273-6.
Title:	Distribution of KRAS and BRAF mutations in Moroccan patients with advanced colorectal cancer.
Author:	Marchoudi, N\|Amrani Hassani Joutei, H\|Jouali, F\|Fekkak, J\|Rhaissi, H
PMID:	23849768

1685.
Journal:	Rev Recent Clin Trials. 2013 Jun;8(2):101-9.
Title:	Cetuximab/irinotecan-chemotherapy in KRAS wild-type pretreated metastatic colorectal cancer: a pooled analysis and review of literature.
Author:	Barni, Sandro\|Ghilardi, Mara\|Borgonovo, Karen\|Cabiddu, Mary\|Zaniboni, Alberto\|Petrelli, Fausto
PMID:	23859115

1686.
Journal:	Ann Surg Oncol. 2013 Oct;20(11):3359-62.
Title:	KRAS mutations and rectal cancer response to chemoradiation: are we closer to personalization of therapy?
Author:	Krishnan, Sunil\|Chang, George J
PMID:	23864308

1687.
Journal:	Cancer. 2013 Oct 1;119(19):3429-35.
Title:	Panitumumab in combination with infusional oxaliplatin and oral capecitabine for conversion therapy in patients with colon cancer and advanced liver metastases. The MetaPan study.
Author:	Leone, Francesco\|Artale, Salvatore\|Marino, Donatella\|Cagnazzo, Celeste\|Cascinu, Stefano\|Pinto, Carmine\|Fornarini, Giuseppe\|Tampellini, Marco\|Di Fabio, Francesca\|Sartore-Bianchi, Andrea\|De Carlis, Luciano\|Pugliese, Raffaele\|Capussotti, Lorenzo\|Gioeni, Luis
PMID:	23868516

1688.
Journal:	Eur J Cancer. 2013 Oct;49(15):3344-52.
Title:	Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.
Author:	Jain, Ajay\|Poonia, Bhawna\|So, Edward C\|Vyzasatya, Ravi\|Burch, Erin E\|Olsen, Henrik S\|Merigeon, Emmanuel Y\|Block, David S\|Zhang, Xiaoyu\|Schulze, Dan H\|Hanna, Nader N\|Twadell, William S\|Yfantis, Harris G\|Chan, Siaw L\|Cai, Ling\|Strome, Scott E
PMID:	23871153

1689.
Journal:	J Nucl Med. 2013 Sep;54(9):1621-9.
Title:	The role of p53 in combination radioimmunotherapy with 64Cu-DOTA-cetuximab and cisplatin in a mouse model of colorectal cancer.
Author:	Guo, Yunjun\|Parry, Jesse J\|Laforest, Richard\|Rogers, Buck E\|Anderson, Carolyn J
PMID:	23873478

1690.
Journal:	PLoS One. 2013 Jul 9;8(7):e68022.
Title:	Colorectal cancer patients with low abundance of KRAS mutation may benefit from EGFR antibody therapy.
Author:	Yu, Shaorong\|Xiao, Xia\|Lu, Jianwei\|Qian, Xiaoping\|Liu, Baorui\|Feng, Jifeng
PMID:	23874486

1691.
Journal:	Eur J Cancer. 2013 Oct;49(15):3076-82.
Title:	Feasibility of preemptive biomarker profiling for personalised early clinical drug development at a Comprehensive Cancer Center.
Author:	Wiesweg, Marcel\|Ting, Saskia\|Reis, Henning\|Worm, Karl\|Kasper, Stefan\|Tewes, Mitra\|Welt, Anja\|Richly, Heike\|Meiler, Johannes\|Bauer, Sebastian\|Hense, Jorg\|Gauler, Thomas C\|Kohler, Jens\|Eberhardt, Wilfried E\|Darwiche, Kaid\|Freitag, Lutz\|Stamatis, Georgios\|Br
PMID:	23876834

1692.
Journal:	J Natl Cancer Inst. 2013 Aug 7;105(15):1151-6.
Title:	Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication.
Author:	Lochhead, Paul\|Kuchiba, Aya\|Imamura, Yu\|Liao, Xiaoyun\|Yamauchi, Mai\|Nishihara, Reiko\|Qian, Zhi Rong\|Morikawa, Teppei\|Shen, Jeanne\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	23878352

1693.
Journal:	Harefuah. 2013 Jun;152(6):326-9, 369.
Title:	[Correlation between the presence of Kras mutation and the presence of the proteins epiregulin and amphiregulin in colon cancer tissue].
Author:	Levi, Yosef\|Barshack, Iris\|Avivi, Kamila\|Bar-ILan, Dalia\|Gutman, Mordechai\|Aderka, Dan\|Berger, Raanan\|Yacobi, Rinat
PMID:	23885463

1694.
Journal:	Harefuah. 2013 Jun;152(6):356-60, 367.
Title:	[Molecular pathology - aspects in KRAS mutation analysis in colon carcinoma].
Author:	Hershkovitz, Dov\|Ben-lzhak, Ofer
PMID:	23885470

1695.
Journal:	Expert Rev Mol Diagn. 2013 Jul;13(6):581-99.
Title:	Colorectal cancer diagnostics: biomarkers, cell-free DNA, circulating tumor cells and defining heterogeneous populations by single-cell analysis.
Author:	Kin, Cindy\|Kidess, Evelyn\|Poultsides, George A\|Visser, Brendan C\|Jeffrey, Stefanie S
PMID:	23895128

1696.
Journal:	Anticancer Res. 2013 Aug;33(8):3053-9.
Title:	The growing galectin network in colon cancer and clinical relevance of cytoplasmic galectin-3 reactivity.
Author:	Dawson, Heather\|Andre, Sabine\|Karamitopoulou, Eva\|Zlobec, Inti\|Gabius, Hans-Joachim
PMID:	23898060

1697.
Journal:	Br J Cancer. 2013 Aug 20;109(4):1004-12.
Title:	Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location.
Author:	Bae, J M\|Kim, J H\|Cho, N-Y\|Kim, T-Y\|Kang, G H
PMID:	23900220

1698.
Journal:	Biomark Med. 2013 Aug;7(4):613-21.
Title:	Microsatellite instability affecting the T17 repeats in intron 8 of HSP110, as well as five mononucleotide repeats in patients with colorectal carcinoma.
Author:	Markovic, Srdjan\|Antic, Jadranka\|Dimitrijevic, Ivan\|Zogovic, Branimir\|Bojic, Daniela\|Svorcan, Petar\|Markovic, Velimir\|Krivokapic, Zoran
PMID:	23905898

1699.
Journal:	PLoS One. 2013 Jul 26;8(7):e69604.
Title:	Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.
Author:	McCourt, Clare M\|McArt, Darragh G\|Mills, Ken\|Catherwood, Mark A\|Maxwell, Perry\|Waugh, David J\|Hamilton, Peter\|O'Sullivan, Joe M\|Salto-Tellez, Manuel
PMID:	23922754

1700.
Journal:	Carcinogenesis. 2013 Nov;34(11):2435-42.
Title:	O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer.
Author:	Fahrer, Jorg\|Kaina, Bernd
PMID:	23929436

1701.
Journal:	Cancer Med. 2013 Jun;2(3):277-85.
Title:	Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab.
Author:	Price, Timothy J\|Hardingham, Jennifer E\|Lee, Chee K\|Townsend, Amanda R\|Wrin, Joseph W\|Wilson, Kate\|Weickhardt, Andrew\|Simes, Robert J\|Murone, Carmel\|Tebbutt, Niall C
PMID:	23930204

1702.
Journal:	Cancer Med. 2013 Jun;2(3):296-304.
Title:	EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients.
Author:	Villalva, Claire\|Duranton-Tanneur, Valerie\|Guilloteau, Karline\|Burel-Vandenbos, Fanny\|Wager, Michel\|Doyen, Jerome\|Levillain, Pierre Marie\|Fontaine, Denys\|Blons, Helene\|Pedeutour, Florence\|Karayan-Tapon, Lucie
PMID:	23930206

1703.
Journal:	Virchows Arch. 2013 Oct;463(4):509-23.
Title:	Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis.
Author:	Neumann, Jens\|Wehweck, Laura\|Maatz, Susanne\|Engel, Jutta\|Kirchner, Thomas\|Jung, Andreas
PMID:	23934607

1704.
Journal:	PLoS One. 2013 Jul 25;8(7):e68945.
Title:	Performance and cost efficiency of KRAS mutation testing for metastatic colorectal cancer in routine diagnosis: the MOKAECM study, a nationwide experience.
Author:	Blons, Helene\|Rouleau, Etienne\|Charrier, Nathanael\|Chatellier, Gilles\|Cote, Jean-Francois\|Pages, Jean-Christophe\|de Fraipont, Florence\|Boyer, Jean-Christophe\|Merlio, Jean Philippe\|Morel, Alain\|Gorisse, Marie-Claude\|de Cremoux, Patricia\|Leroy, Karen\|Milano
PMID:	23935912

1705.
Journal:	PLoS One. 2013 Aug 1;8(8):e70604.
Title:	TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells.
Author:	Luu, Carrie\|Heinrich, Eileen L\|Duldulao, Marjun\|Arrington, Amanda K\|Fakih, Marwan\|Garcia-Aguilar, Julio\|Kim, Joseph
PMID:	23936455

1706.
Journal:	Clin Chem. 2013 Dec;59(12):1722-31.
Title:	Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients.
Author:	Taly, Valerie\|Pekin, Deniz\|Benhaim, Leonor\|Kotsopoulos, Steve K\|Le Corre, Delphine\|Li, Xinyu\|Atochin, Ivan\|Link, Darren R\|Griffiths, Andrew D\|Pallier, Karine\|Blons, Helene\|Bouche, Olivier\|Landi, Bruno\|Hutchison, J Brian\|Laurent-Puig, Pierre
PMID:	23938455

1707.
Journal:	Med Oncol. 2013;30(3):686.
Title:	Pattern of clinically relevant mutations in consecutive series of Russian colorectal cancer patients.
Author:	Yanus, Grigoriy A\|Belyaeva, Anna V\|Ivantsov, Alexandr O\|Kuligina, Ekatherina Sh\|Suspitsin, Evgeny N\|Mitiushkina, Natalia V\|Aleksakhina, Svetlana N\|Iyevleva, Aglaya G\|Zaitseva, Olga A\|Yatsuk, Olga S\|Gorodnova, Tatiana V\|Strelkova, Tatiana N\|Efremova, Sofia
PMID:	23943423

1708.
Journal:	Onco Targets Ther. 2013 Aug 5;6:1057-64.
Title:	454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples.
Author:	Altimari, Annalisa\|de Biase, Dario\|De Maglio, Giovanna\|Gruppioni, Elisa\|Capizzi, Elisa\|Degiovanni, Alessio\|D'Errico, Antonia\|Pession, Annalisa\|Pizzolitto, Stefano\|Fiorentino, Michelangelo\|Tallini, Giovanni
PMID:	23950653

1709.
Journal:	BMC Gastroenterol. 2013 Aug 19;13:129.
Title:	Morphological change of a laterally spreading rectal tumor over a short period.
Author:	Miyamoto, Hideaki\|Oono, Yasuhiro\|Fu, Kuang-l\|Ikematsu, Hiroaki\|Fujii, Satoshi\|Kojima, Takashi\|Yano, Tomonori\|Ochiai, Atsushi\|Sasaki, Yutaka\|Kaneko, Kazuhiro
PMID:	23957258

1710.
Journal:	Mol Cancer Ther. 2013 Oct;12(10):2121-34.
Title:	Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.
Author:	Mazard, Thibault\|Causse, Annick\|Simony, Joelle\|Leconet, Wilhem\|Vezzio-Vie, Nadia\|Torro, Adeline\|Jarlier, Marta\|Evrard, Alexandre\|Del Rio, Maguy\|Assenat, Eric\|Martineau, Pierre\|Ychou, Marc\|Robert, Bruno\|Gongora, Celine
PMID:	23960095

1711.
Journal:	Cancer Epidemiol. 2013 Oct;37(5):556-61.
Title:	Distinct molecular features of colorectal cancer in Ghana.
Author:	Raskin, Leon\|Dakubo, Jonathan C B\|Palaski, Nicole\|Greenson, Joel K\|Gruber, Stephen B
PMID:	23962701

1712.
Journal:	J Phys Chem B. 2013 Oct 3;117(39):11584-95.
Title:	Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment.
Author:	Sanders, Jeffrey M\|Wampole, Matthew E\|Chen, Chang-Po\|Sethi, Dalip\|Singh, Amrita\|Dupradeau, Francois-Yves\|Wang, Fan\|Gray, Brian D\|Thakur, Mathew L\|Wickstrom, Eric
PMID:	23972113

1713.
Journal:	Mol Med. 2013 Sep 10;19:286-93.
Title:	Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I-III colon cancers.
Author:	Berg, Marianne\|Guriby, Marianne\|Nordgard, Oddmund\|Nedrebo, Bjorn S\|Ahlquist, Terje C\|Smaaland, Rune\|Oltedal, Satu\|Soreide, Jon Arne\|Korner, Hartwig\|Lothe, Ragnhild A\|Soreide, Kjetil
PMID:	23979710

1714.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Aug;16(8):718-20.
Title:	[Consideration of therapy for colorectal cancer with synchronous unresectable liver metastasis].
Author:	Zhu, De-xiang\|Ren, Li\|Xu, Jian-min
PMID:	23980038

1715.
Journal:	Carcinogenesis. 2013 Dec;34(12):2757-66.
Title:	Dietary heme iron and the risk of colorectal cancer with specific mutations in KRAS and APC.
Author:	Gilsing, Anne M J\|Fransen, Fiona\|de Kok, Theo M\|Goldbohm, Alexandra R\|Schouten, Leo J\|de Bruine, Adriaan P\|van Engeland, Manon\|van den Brandt, Piet A\|de Goeij, Anton F P M\|Weijenberg, Matty P
PMID:	23983135

1716.
Journal:	World J Gastroenterol. 2013 Aug 28;19(32):5286-94.
Title:	Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.
Author:	Aissi, Sana\|Buisine, Marie Pierre\|Zerimech, Farid\|Kourda, Nadia\|Moussa, Amel\|Manai, Mohamed\|Porchet, Nicole
PMID:	23983431

1717.
Journal:	Gan To Kagaku Ryoho. 2013 Aug;40(8):1115-8.
Title:	[A case of metastatic colorectal cancer with icterus due to multiple liver metastases treated effectively by FOLFOX plus bevacizumab].
Author:	Terasawa, Takayuki\|Koja, Susumu\|Yasuda, Koji\|Fukuda, Kaori
PMID:	23986063

1718.
Journal:	APMIS. 2013 Oct;121(10):954-66.
Title:	Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia.
Author:	Yip, Wai Kien\|Choo, Chee Wei\|Leong, Vincent Ching-Shian\|Leong, Pooi Pooi\|Jabar, Mohd Faisal\|Seow, Heng Fong
PMID:	23992303

1719.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):264-84.
Title:	The status of targeted agents in the setting of neoadjuvant radiation therapy in locally advanced rectal cancers.
Author:	Glynne-Jones, Rob\|Hadaki, Maher\|Harrison, Mark
PMID:	23997939

1720.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):285-98.
Title:	Integrating anti-EGFR therapies in metastatic colorectal cancer.
Author:	Haraldsdottir, Sigurdis\|Bekaii-Saab, Tanios
PMID:	23997940

1721.
Journal:	J Gastrointest Oncol. 2013 Sep;4(3):308-18.
Title:	Markers of resistance to anti-EGFR therapy in colorectal cancer.
Author:	Shaib, Walid\|Mahajan, Reena\|El-Rayes, Bassel
PMID:	23997942

1722.
Journal:	Int J Biol Markers. 2013 Dec 17;28(4):e393-7.
Title:	K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011.
Author:	Ruiz-Candelaria, Yelitza\|Miranda-Diaz, Christine\|Hunter-Mellado, Robert F
PMID:	23999847

1723.
Journal:	Dtsch Med Wochenschr. 2013 Sep;138(36):1790-5.
Title:	[Colorectal cancer - personalized, stage-adjusted tumour therapy].
Author:	Pohl, M\|Schmiegel, W
PMID:	24002881

1724.
Journal:	Cancer Prev Res (Phila). 2013 Sep;6(9):898-907.
Title:	Ultrasensitive detection of unknown colon cancer-initiating mutations using the example of the Adenomatous polyposis coli gene.
Author:	Gerecke, Christian\|Mascher, Conny\|Gottschalk, Uwe\|Kleuser, Burkhard\|Scholtka, Bettina
PMID:	24005794

1725.
Journal:	BMC Cancer. 2013 Sep 3;13:405.
Title:	Simultaneous identification of 36 mutations in KRAS codons 61 and 146, BRAF, NRAS, and PIK3CA in a single reaction by multiplex assay kit.
Author:	Bando, Hideaki\|Yoshino, Takayuki\|Shinozaki, Eiji\|Nishina, Tomohiro\|Yamazaki, Kentaro\|Yamaguchi, Kensei\|Yuki, Satoshi\|Kajiura, Shinya\|Fujii, Satoshi\|Yamanaka, Takeharu\|Tsuchihara, Katsuya\|Ohtsu, Atsushi
PMID:	24006859

1726.
Journal:	Clin Colorectal Cancer. 2013 Dec;12(4):280-6.
Title:	Prognostic value of the combination of circulating tumor cells plus KRAS in patients with metastatic colorectal cancer treated with chemotherapy plus bevacizumab.
Author:	Sastre, Javier\|Vidaurreta, Marta\|Gomez, Auxiliadora\|Rivera, Fernando\|Massuti, Bartomeu\|Lopez, Margarita Reboredo\|Abad, Albert\|Gallen, Manuel\|Benavides, Manuel\|Aranda, Enrique\|Rubio, Eduardo Diaz
PMID:	24012456

1727.
Journal:	J Clin Oncol. 2013 Oct 10;31(29):3664-72.
Title:	Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy.
Author:	Sinicrope, Frank A\|Mahoney, Michelle R\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Warren, Robert S\|Bertagnolli, Monica M\|Nelson, Garth D\|Goldberg, Richard M\|Sargent, Daniel J\|Alberts, Steven R
PMID:	24019539

1728.
Journal:	Biol Sex Differ. 2013 Sep 10;4(1):17.
Title:	Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study.
Author:	Wangefjord, Sakarias\|Sundstrom, Magnus\|Zendehrokh, Nooreldin\|Lindquist, Kajsa Ericson\|Nodin, Bjorn\|Jirstrom, Karin\|Eberhard, Jakob
PMID:	24020794

1729.
Journal:	Anticancer Res. 2013 Sep;33(9):3905-10.
Title:	Circulating tumor cell (CTC) count and epithelial growth factor receptor expression on CTCs as biomarkers for cetuximab efficacy in advanced colorectal cancer.
Author:	Kuboki, Yasutoshi\|Matsusaka, Satoshi\|Minowa, Sayuri\|Shibata, Harumi\|Suenaga, Mitsukuni\|Shinozaki, Eiji\|Mizunuma, Nobuyuki\|Ueno, Masashi\|Yamaguchi, Toshiharu\|Hatake, Kiyohiko
PMID:	24023327

1730.
Journal:	N Engl J Med. 2013 Sep 12;369(11):1023-34.
Title:	Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.
Author:	Douillard, Jean-Yves\|Oliner, Kelly S\|Siena, Salvatore\|Tabernero, Josep\|Burkes, Ronald\|Barugel, Mario\|Humblet, Yves\|Bodoky, Gyorgy\|Cunningham, David\|Jassem, Jacek\|Rivera, Fernando\|Kocakova, Ilona\|Ruff, Paul\|Blasinska-Morawiec, Maria\|Smakal, Martin\|Canon, J
PMID:	24024839

1731.
Journal:	Cancer Biol Ther. 2013 Oct 1;14(10):877-8.
Title:	Multi-kinase modulation for colon cancer therapy.
Author:	Dent, Paul
PMID:	24025253

1732.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1098-103.
Title:	Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy.
Author:	Pietrantonio, Filippo\|Perrone, Federica\|Biondani, Pamela\|Maggi, Claudia\|Lampis, Andrea\|Bertan, Claudia\|Venturini, Filippo\|Tondulli, Luca\|Ferrari, Daris\|Ricci, Vincenzo\|Villa, Federica\|Barone, Gloria\|Bianco, Nadia\|Ghidini, Antonio\|Bossi, Ilaria\|Fanetti, Gi
PMID:	24025413

1733.
Journal:	Cancer Biol Ther. 2013 Dec;14(12):1143-6.
Title:	The S492R EGFR ectodomain mutation is never detected in KRAS wild-type colorectal carcinoma before exposure to EGFR monoclonal antibodies.
Author:	Esposito, Claudia\|Rachiglio, Anna Maria\|La Porta, Maria Libera\|Sacco, Alessandra\|Roma, Cristin\|Iannaccone, Alessia\|Tatangelo, Fabiana\|Forgione, Laura\|Pasquale, Raffaella\|Barbaro, Americo\|Botti, Gerardo\|Ciardiello, Fortunato\|Normanno, Nicola
PMID:	24025416

1734.
Journal:	Hum Mutat. 2013 Nov;34(11):1568-80.
Title:	Sensitive detection of KRAS mutations using enhanced-ice-COLD-PCR mutation enrichment and direct sequence identification.
Author:	How Kit, Alexandre\|Mazaleyrat, Nicolas\|Daunay, Antoine\|Nielsen, Helene Myrtue\|Terris, Benoit\|Tost, Jorg
PMID:	24038839

1735.
Journal:	Am J Gastroenterol. 2013 Nov;108(11):1785-93.
Title:	Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Author:	Mouradov, Dmitri\|Domingo, Enric\|Gibbs, Peter\|Jorissen, Robert N\|Li, Shan\|Soo, Pik Ying\|Lipton, Lara\|Desai, Jayesh\|Danielsen, Havard E\|Oukrif, Dahmane\|Novelli, Marco\|Yau, Christopher\|Holmes, Christopher C\|Jones, Ian T\|McLaughlin, Stephen\|Molloy, Peter\|Hawk
PMID:	24042191

1736.
Journal:	Oncogenesis. 2013 Sep 16;2:e71.
Title:	Epigenetic and genetic features of 24 colon cancer cell lines.
Author:	Ahmed, D\|Eide, P W\|Eilertsen, I A\|Danielsen, S A\|Eknaes, M\|Hektoen, M\|Lind, G E\|Lothe, R A
PMID:	24042735

1737.
Journal:	Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):140-9. eCollection 2013.
Title:	Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia.
Author:	Abbenhardt, Clare\|Poole, Elizabeth M\|Kulmacz, Richard J\|Xiao, Liren\|Curtin, Karen\|Galbraith, Rachel L\|Duggan, David\|Hsu, Li\|Makar, Karen W\|Caan, Bette J\|Koepl, Lisel\|Owen, Robert W\|Scherer, Dominique\|Carlson, Christopher S\|Potter, John D\|Slattery, Martha
PMID:	24046806

1738.
Journal:	Neoplasma. 2013 Sep 20.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24050544

1739.
Journal:	Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2.
Title:	The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
Author:	Strimpakos, Alexios\|Pentheroudakis, George\|Kotoula, Vassiliki\|De Roock, Wendy\|Kouvatseas, George\|Papakostas, Pavlos\|Makatsoris, Thomas\|Papamichael, Demetris\|Andreadou, Anna\|Sgouros, Joseph\|Zizi-Sermpetzoglou, Adamantia\|Kominea, Athina\|Televantou, Despina\|
PMID:	24050852

1740.
Journal:	Clin Ther. 2013 Sep;35(9):1282-303.
Title:	Epidermal growth factor receptor: pathway, therapies, and pipeline.
Author:	Goffin, John R\|Zbuk, Kevin
PMID:	24054705

1741.
Journal:	Se Pu. 2013 Jun;31(6):582-6.
Title:	[Determination of K-ras gene mutation in colorectal cancer tissue by capillary electrophoresis].
Author:	Shi, Dongqin\|Wang, Rong\|Xie, Hua\|Tian, Wei\|Jia, Zhengping\|Guo, Jiankui
PMID:	24063200

1742.
Journal:	Rom J Morphol Embryol. 2013;54(3):567-74.
Title:	K-ras gene mutation status in colorectal cancer: comparative analysis of pyrosequencing and PCR-RFLP.
Author:	Dobre, Maria\|Comanescu, Maria\|Arsene, D\|Iosif, Cristina\|Bussolati, G
PMID:	24068405

1743.
Journal:	BMC Cancer. 2013 Sep 27;13:439.
Title:	Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer.
Author:	Popovici, Vlad\|Budinska, Eva\|Bosman, Fred T\|Tejpar, Sabine\|Roth, Arnaud D\|Delorenzi, Mauro
PMID:	24073892

1744.
Journal:	Mol Biol Rep. 2013 Nov;40(11):6107-12.
Title:	KRAS mutations in colorectal cancer from Tunisia: relationships with clinicopathologic variables and data on TP53 mutations and microsatellite instability.
Author:	Aissi, Sana\|Buisine, Marie-Pierre\|Zerimech, Farid\|Kourda, Nadia\|Moussa, Amel\|Manai, Mohamed\|Porchet, Nicole
PMID:	24078161

1745.
Journal:	Protein Cell. 2013 Nov;4(11):807-12.
Title:	The enigmatic ERH protein: its role in cell cycle, RNA splicing and cancer.
Author:	Weng, Meng-Tzu\|Luo, Ji
PMID:	24078386

1746.
Journal:	Virchows Arch. 2013 Nov;463(5):623-31.
Title:	Ultra-deep sequencing confirms immunohistochemistry as a highly sensitive and specific method for detecting BRAF V600E mutations in colorectal carcinoma.
Author:	Rossle, Matthias\|Sigg, Michele\|Ruschoff, Jan H\|Wild, Peter J\|Moch, Holger\|Weber, Achim\|Rechsteiner, Markus P
PMID:	24085553

1747.
Journal:	Drugs Today (Barc). 2013 Sep;49(9):523-35.
Title:	Afatinib for the treatment of patients with EGFR-positive non-small cell lung cancer.
Author:	Bowles, D W\|Weickhardt, A\|Jimeno, A
PMID:	24086949

1748.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2857-63.
Title:	Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations.
Author:	Ganesan, Prasanth\|Janku, Filip\|Naing, Aung\|Hong, David S\|Tsimberidou, Apostolia M\|Falchook, Gerald S\|Wheler, Jennifer J\|Piha-Paul, Sarina A\|Fu, Siqing\|Stepanek, Vanda M\|Lee, J Jack\|Luthra, Rajyalakshmi\|Overman, Michael J\|Kopetz, E Scott\|Wolff, Robert A\|Ku
PMID:	24092809

1749.
Journal:	J Med Econ. 2013 Dec;16(12):1387-98.
Title:	Economic analysis of bevacizumab, cetuximab, and panitumumab with fluoropyrimidine-based chemotherapy in the first-line treatment of KRAS wild-type metastatic colorectal cancer (mCRC).
Author:	Lawrence, Donna\|Maschio, Michael\|Leahy, Kevin J\|Yunger, Simon\|Easaw, Jacob C\|Weinstein, Milton C
PMID:	24102083

1750.
Journal:	Cancer. 2013 Dec 1;119(23):4137-44.
Title:	Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases.
Author:	Karagkounis, Georgios\|Torbenson, Michael S\|Daniel, Hubert D\|Azad, Nilofer S\|Diaz, Luis A Jr\|Donehower, Ross C\|Hirose, Kenzo\|Ahuja, Nita\|Pawlik, Timothy M\|Choti, Michael A
PMID:	24104864

1751.
Journal:	Cancer. 2013 Dec 15;119(24):4223-30.
Title:	Randomized phase 2 study of pegylated SN-38 (EZN-2208) or irinotecan plus cetuximab in patients with advanced colorectal cancer.
Author:	Garrett, Christopher R\|Bekaii-Saab, Tanios S\|Ryan, Theresa\|Fisher, George A\|Clive, Sally\|Kavan, Petr\|Shacham-Shmueli, Einat\|Buchbinder, Aby\|Goldberg, Richard M
PMID:	24105075

1752.
Journal:	Mol Cancer Ther. 2013 Dec;12(12):2950-61.
Title:	BRAF V600E is a determinant of sensitivity to proteasome inhibitors.
Author:	Zecchin, Davide\|Boscaro, Valentina\|Medico, Enzo\|Barault, Ludovic\|Martini, Miriam\|Arena, Sabrina\|Cancelliere, Carlotta\|Bartolini, Alice\|Crowley, Emily H\|Bardelli, Alberto\|Gallicchio, Margherita\|Di Nicolantonio, Federica
PMID:	24107445

1753.
Journal:	Cancer. 2013 Dec 1;119(23):4145-53.
Title:	Intermittent versus continuous erlotinib with concomitant modified "XELOX" (q3W) in first-line treatment of metastatic colorectal cancer: correlation with serum amphiregulin and transforming growth factor alpha.
Author:	Ma, Brigette B Y\|Chan, Stephen L\|Ho, Wing M\|Lau, Wilson\|Mo, Frankie\|Hui, Edwin P\|Chan, Charles\|Poon, Annette\|Dattatray, Rasalkar D\|Wong, S C Cesar\|To, Ka F\|King, Ann D\|Ahuja, Anil\|Chan, Anthony T C
PMID:	24114668

1754.
Journal:	Clin Cancer Res. 2013 Dec 15;19(24):6751-65.
Title:	Increased TGF-alpha as a mechanism of acquired resistance to the anti-EGFR inhibitor cetuximab through EGFR-MET interaction and activation of MET signaling in colon cancer cells.
Author:	Troiani, Teresa\|Martinelli, Erika\|Napolitano, Stefania\|Vitagliano, Donata\|Ciuffreda, Loreta Pia\|Costantino, Sara\|Morgillo, Floriana\|Capasso, Anna\|Sforza, Vincenzo\|Nappi, Anna\|De Palma, Raffaele\|D'Aiuto, Elena\|Berrino, Liberato\|Bianco, Roberto\|Ciardiello,
PMID:	24122793

1755.
Journal:	Oncology (Williston Park). 2013 Aug;27(8):746-54.
Title:	Use of molecular biomarkers to inform adjuvant therapy for colon cancer.
Author:	Mettu, Niharika B\|Hurwitz, Herbert\|Hsu, David S
PMID:	24133820

1756.
Journal:	Ann Oncol. 2013 Dec;24(12):3123-8.
Title:	HER2 in high-risk rectal cancer patients treated in EXPERT-C, a randomized phase II trial of neoadjuvant capecitabine and oxaliplatin (CAPOX) and chemoradiotherapy (CRT) with or without cetuximab.
Author:	Sclafani, F\|Roy, A\|Cunningham, D\|Wotherspoon, A\|Peckitt, C\|Gonzalez de Castro, D\|Tabernero, J\|Glimelius, B\|Cervantes, A\|Eltahir, Z\|Oates, J\|Chau, I
PMID:	24146218

1757.
Journal:	Transl Oncol. 2013 Oct 1;6(5):528-38. eCollection 2013.
Title:	Mutational Analysis of Circulating Tumor Cells Using a Novel Microfluidic Collection Device and qPCR Assay.
Author:	Harb, Wael\|Fan, Andrea\|Tran, Tony\|Danila, Daniel C\|Keys, David\|Schwartz, Michael\|Ionescu-Zanetti, Cristian
PMID:	24151533

1758.
Journal:	BMC Med Genomics. 2013 Oct 23;6:43.
Title:	Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway.
Author:	Wormald, Samuel\|Milla, Liz\|O'Connor, Liam
PMID:	24152305

1759.
Journal:	Medicina (B Aires). 2013;73(5):417-22.
Title:	[Clinical-pathological features and gene profile in colorectal cancer].
Author:	Perazzo, Florencia\|Piaggio, Fernando\|Krupitzki, Hugo\|Garcia, Alejandro\|Avagnina, Alejandra\|Elsner, Boris\|Denninghoff, Valeria
PMID:	24152396

1760.
Journal:	Cancer Med. 2013 Aug;2(4):496-506.
Title:	PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival.
Author:	Atreya, Chloe E\|Sangale, Zaina\|Xu, Nafei\|Matli, Mary R\|Tikishvili, Eliso\|Welbourn, William\|Stone, Steven\|Shokat, Kevan M\|Warren, Robert S
PMID:	24156022

1761.
Journal:	Future Oncol. 2013 Nov;9(11):1687-91.
Title:	A perspective on the current management of advanced colorectal cancer.
Author:	Casagrande, Mariaelena\|Cremolini, Chiara\|Loupakis, Fotios\|Aprile, Giuseppe
PMID:	24156327

1762.
Journal:	J Natl Compr Canc Netw. 2013 Sep;11 Suppl 4:S9-17.
Title:	Multigene assays in metastatic colorectal cancer.
Author:	Deeb, Kristin K\|Sram, Jakub P\|Gao, Hanlin\|Fakih, Marwan G
PMID:	24158971

1763.
Journal:	J Clin Oncol. 2013 Dec 10;31(35):e448-51.
Title:	BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.
Author:	Andrews, Miles C\|Behren, Andreas\|Chionh, Fiona\|Mariadason, John\|Vella, Laura J\|Do, Hongdo\|Dobrovic, Alexander\|Tebbutt, Niall\|Cebon, Jonathan
PMID:	24190114

1764.
Journal:	Br J Cancer. 2013 Dec 10;109(12):3057-66.
Title:	Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.
Author:	Aparicio, T\|Svrcek, M\|Zaanan, A\|Beohou, E\|Laforest, A\|Afchain, P\|Mitry, Emmanuel\|Taieb, J\|Di Fiore, F\|Gornet, J-M\|Thirot-Bidault, A\|Sobhani, I\|Malka, D\|Lecomte, T\|Locher, C\|Bonnetain, F\|Laurent-Puig, P
PMID:	24196786

1765.
Journal:	Cancer Genet. 2013 Sep-Oct;206(9-10):330-9.
Title:	Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients.
Author:	Jiang, Liyan\|Huang, Jiaqi\|Morehouse, Chris\|Zhu, Wei\|Korolevich, Susana\|Sui, Dan\|Ge, Xiaoxiao\|Lehmann, Kim\|Liu, Zheng\|Kiefer, Christine\|Czapiga, Meggan\|Su, Xinying\|Brohawn, Philip\|Gu, Yi\|Higgs, Brandon W\|Yao, Yihong
PMID:	24200637

1766.
Journal:	PLoS One. 2013 Oct 21;8(10):e77901.
Title:	Can K-ras gene mutation be utilized as prognostic biomarker for colorectal cancer patients receiving chemotherapy? A meta-analysis and systematic review.
Author:	Rui, Yuan-Yi\|Zhang, Dan\|Zhou, Zong-Guang\|Wang, Cun\|Yang, Lie\|Yu, Yong-Yang\|Chen, Hai-Ning
PMID:	24205021

1767.
Journal:	Int J Radiat Oncol Biol Phys. 2013 Dec 1;87(5):992-9.
Title:	Preoperative chemoradiation therapy with capecitabine/oxaliplatin and cetuximab in rectal cancer: long-term results of a prospective phase 1/2 study.
Author:	Fokas, Emmanouil\|Conradi, Lena\|Weiss, Christian\|Sprenger, Thilo\|Middel, Peter\|Rau, Tillman\|Dellas, Kathrin\|Kitz, Julia\|Rodel, Franz\|Sauer, Rolf\|Ruschoff, Josef\|Beissbarth, Tim\|Arnold, Dirk\|Ghadimi, B Michael\|Rodel, Claus\|Liersch, Torsten
PMID:	24210078

1768.
Journal:	Biochem Biophys Res Commun. 2013 Nov 29;441(4):707-12.
Title:	The interplay between epigenetic silencing, oncogenic KRas and HIF-1 regulatory pathways in control of BNIP3 expression in human colorectal cancer cells.
Author:	Swiderek, Ewelina\|Kalas, Wojciech\|Wysokinska, Edyta\|Pawlak, Alicja\|Rak, Janusz\|Strzadala, Leon
PMID:	24211581

1769.
Journal:	J Natl Cancer Inst. 2013 Dec 4;105(23):1789-98.
Title:	Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial.
Author:	Ogino, Shuji\|Liao, Xiaoyun\|Imamura, Yu\|Yamauchi, Mai\|McCleary, Nadine J\|Ng, Kimmie\|Niedzwiecki, Donna\|Saltz, Leonard B\|Mayer, Robert J\|Whittom, Renaud\|Hantel, Alexander\|Benson, Al B 3rd\|Mowat, Rex B\|Spiegelman, Donna\|Goldberg, Richard M\|Bertagnolli, Monic
PMID:	24231454

1770.
Journal:	PLoS One. 2013 Nov 11;8(11):e80437.
Title:	Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients.
Author:	Gandhi, Anita K\|Shi, Tao\|Li, Mingyu\|Jungnelius, Ulf\|Romano, Alfredo\|Tabernero, Josep\|Siena, Salvatore\|Schafer, Peter H\|Chopra, Rajesh
PMID:	24244687

1771.
Journal:	J Clin Oncol. 2013 Dec 20;31(36):4562-8.
Title:	Evaluating many treatments and biomarkers in oncology: a new design.
Author:	Kaplan, Richard\|Maughan, Timothy\|Crook, Angela\|Fisher, David\|Wilson, Richard\|Brown, Louise\|Parmar, Mahesh
PMID:	24248692

1772.
Journal:	Clin Lab Med. 2013 Dec;33(4):835-59.
Title:	Molecular diagnostics in colorectal carcinoma.
Author:	Bhalla, Amarpreet\|Zulfiqar, Muhammad\|Weindel, Michael\|Shidham, Vinod B
PMID:	24267189

1773.
Journal:	Cancer Manag Res. 2013 Nov 21;5:387-400.
Title:	Personalized treatment for advanced colorectal cancer: KRAS and beyond.
Author:	Patel, Gargi Surendra\|Karapetis, Christos S
PMID:	24294007

1774.
Journal:	BMC Res Notes. 2013 Dec 5;6:508.
Title:	Acquired drug resistance conferred by a KRAS gene mutation following the administration of cetuximab: a case report.
Author:	Osumi, Hiroki\|Matsusaka, Satoshi\|Shinozaki, Eiji\|Suenaga, Mitsukuni\|Mingyon, Mun\|Saiura, Akio\|Ueno, Masashi\|Mizunuma, Nobuyuki\|Yamaguchi, Toshiharu
PMID:	24304820

1775.
Journal:	Biomed Res Int. 2013;2013:143273.
Title:	Effectiveness and safety of intensive triplet chemotherapy plus bevacizumab, FIr-B/FOx, in young-elderly metastatic colorectal cancer patients.
Author:	Bruera, Gemma\|Cannita, Katia\|Giordano, Aldo Victor\|Vicentini, Roberto\|Ficorella, Corrado\|Ricevuto, Enrico
PMID:	24307987

1776.
Journal:	BMC Cancer. 2013 Dec 13;13:599.
Title:	The prognostic values of EGFR expression and KRAS mutation in patients with synchronous or metachronous metastatic colorectal cancer.
Author:	Huang, Ching-Wen\|Tsai, Hsiang-Lin\|Chen, Yi-Ting\|Huang, Chun-Ming\|Ma, Cheng-Jen\|Lu, Chien-Yu\|Kuo, Chao-Hung\|Wu, Deng-Chyang\|Chai, Chee-Yin\|Wang, Jaw-Yuan
PMID:	24330663

1777.
Journal:	PLoS One. 2013 Dec 10;8(12):e81628.
Title:	Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.
Author:	Shen, Yinchen\|Wang, Jianfei\|Han, Xiaohong\|Yang, Hongying\|Wang, Shuai\|Lin, Dongmei\|Shi, Yuankai
PMID:	24339949

1778.
Journal:	Onkologie. 2013;36(12):719-24.
Title:	RAS, BRAF, and TP53 gene mutations in Taiwanese colorectal cancer patients.
Author:	Chang, Ya-Sian\|Chang, Shun-Jen\|Yeh, Kun-Tu\|Lin, Tsai-Hsiu\|Chang, Jan-Gowth
PMID:	24356563

1779.
Journal:	World J Gastroenterol. 2013 Dec 14;19(46):8474-88.
Title:	Evidence-based appraisal of the upfront treatment for unresectable metastatic colorectal cancer patients.
Author:	Aprile, Giuseppe\|Lutrino, Stefania Eufemia\|Ferrari, Laura\|Casagrande, Mariaelena\|Bonotto, Marta\|Ongaro, Elena\|Puglisi, Fabio
PMID:	24379565

1780.
Journal:	Gan To Kagaku Ryoho. 2013 Nov;40(12):1714-6.
Title:	[Outcomes of patients with small bowel carcinoma treated with appropriate chemotherapy selected on the basis of genetic analysis findings].
Author:	Suzuki, Okihide\|Ishibashi, Keiichiro\|Imaizumi, Hideko\|Amano, Kunihiko\|Hatano, Satoshi\|Matsuzawa, Takeaki\|Ogita, Tomohiko\|Kuwabara, Koki\|Sobajima, Jun\|Ishiguro, Toru\|Higashi, Morihiro\|Fukuchi, Minoru\|Kumamoto, Keisuke\|Baba, Hiroyuki\|Kumagai, Yoichi\|Tsuji,
PMID:	24393898

1781.
Journal:	Gan To Kagaku Ryoho. 2013 Nov;40(12):2008-10.
Title:	[A case of recurrent rectal cancer successfully treated for a long period with capecitabine plus oxaliplatin and bevacizumab therapy].
Author:	Iwata, Noriko\|Ishikawa, Toshiaki\|Takahashi, Hidenori\|Baba, Hironobu\|Masuda, Daiki\|Okazaki, Satoshi\|Matsuyama, Takatoshi\|Ishiguro, Megumi\|Kobayashi, Hirotoshi\|Iida, Satoru\|Uetake, Hiroyuki\|Sugihara, Kenichi
PMID:	24393995

1782.
Journal:	Cancer Med. 2013 Dec;2(6):881-8.
Title:	Oncologists' attitudes toward KRAS testing: a multisite study.
Author:	Harris, Julie N\|Liljestrand, Petra\|Alexander, Gwen L\|Goddard, Katrina A B\|Kauffman, Tia\|Kolevska, Tatjana\|McCarty, Catherine\|O'Neill, Suzanne\|Pawloski, Pamala\|Rahm, Alanna\|Williams, Andrew\|Somkin, Carol P
PMID:	24403261

1783.
Journal:	Pathol Int. 2013 Dec;63(12):611-4.
Title:	KRAS mutation positive mucinous adenocarcinoma originating in mature ovarian teratoma: case report and review of literature.
Author:	Hershkovitz, Dov\|Vlodavsky, Euvgeni\|Simon, Einav\|Ben-Izhak, Ofer
PMID:	24422958

1784.
Journal:	Cancer Biomark. 2013;13(5):359-66.
Title:	Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.
Author:	Kang, Melissa\|Shen, Xiang J\|Kim, Sangmi\|Araujo-Perez, Felix\|Galanko, Joseph A\|Martin, Chris F\|Sandler, Robert S\|Keku, Temitope O
PMID:	24440976

1785.
Journal:	Ann Coloproctol. 2013 Dec;29(6):252-5.
Title:	Rhabdoid carcinoma of the rectum.
Author:	Samalavicius, Narimantas Evaldas\|Stulpinas, Rokas\|Gasilionis, Valdas\|Baltruskeviciene, Edita\|Aleknavicius, Eduardas\|Mickys, Ugnius
PMID:	24466541

1786.
Journal:	Rev Med Chil. 2013 Sep;141(9):1166-72.
Title:	[KRAS gene mutation in colorectal cancer].
Author:	Roa, Ivan\|Sanchez, Tamara\|Majlis, Alejandro\|Schalper, Kurt
PMID:	24522420

1787.
Journal:	Anal Quant Cytopathol Histpathol. 2013 Dec;35(6):324-34.
Title:	Inhibition of beta-catenin and KRAS expressions by Piper betle in azoxymethane-induced colon cancer of male Fischer 344 rats.
Author:	Esa, Faezah\|Ngah, Wan Zurinah Wan\|Jamal, A Rahman A\|Mohd Yusof, Yasmin Anum
PMID:	24617038

1788.
Journal:	Vopr Onkol. 2013;59(6):751-5.
Title:	[The frequency and spectrum of KRAS mutations in metastatic colorectal cancer].
Author:	Mazurenko, N N\|Gagarin, I M\|Tsyganova, I V\|Mochal'nikova, V V\|Breder, V V
PMID:	24624786

1789.
Journal:	Mol Clin Oncol. 2013 Mar;1(2):291-296.
Title:	Analysis of the anatomic subsites, gender and age in unresectable advanced colorectal carcinomas in Tochigi, Japan suggests a shift in location towards the right side colon in elderly patients treated with cetuximab.
Author:	Tanaka, Toshio\|Ichikawa, Kazuhito\|Maruoka, Takashi\|Tomita, Shigeki\|Ueda, Hirofumi\|Yamaguchi, Takeshi\|Shida, Yosuke\|Kato, Hiroyuki\|Nagata, Hitoshi\|Kubota, Keiichi\|Akimoto, Naohiko\|Sakamoto, Chouitsu\|Imura, Johji\|Arita, Munefumi\|Tanaka, Hiroyuki\|Okamoto, Yo
PMID:	24649163

1790.
Journal:	Gastroenterol Rep (Oxf). 2013 Nov;1(3):166-83.
Title:	Biomarkers in precision therapy in colorectal cancer.
Author:	Reimers, Marlies S\|Zeestraten, Eliane C M\|Kuppen, Peter J K\|Liefers, Gerrit Jan\|van de Velde, Cornelis J H
PMID:	24759962

1791.
Journal:	Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):6-13.
Title:	Clinical implications of BRAF mutation test in colorectal cancer.
Author:	Nazemalhosseini Mojarad, Ehsan\|Farahani, Roya Kishani\|Haghighi, Mahdi Montazer\|Aghdaei, Hamid Asadzadeh\|Kuppen, Peter Jk\|Zali, Mohammad Reza
PMID:	24834238

1792.
Journal:	World J Oncol. 2013 Oct;4(4-5):179-187.
Title:	Clinical-Pathological Correlation of KRAS Mutation Status in Metastatic Colorectal Adenocarcinoma.
Author:	Ribeiro, Karen Bento\|Ribeiro, Karoline Bento\|Feres, Omar\|da Rocha, Jose Joaquim Ribeiro\|Rapatoni, Liane\|Garcia, Sergio Britto\|Silva, Alfredo Ribeiro\|da Silva Castro Perdona, Gleici\|de Souza, Hayala Cristina Cavenague\|Santillan, Saul Isaac Garrido\|de Olive
PMID:	29147353

1793.
Journal:	Mol Carcinog. 2014 Feb;53 Suppl 1:E181-6.
Title:	Evidence for possible non-canonical pathway(s) driven early-onset colorectal cancer in India.
Author:	Raman, Ratheesh\|Kotapalli, Viswakalyan\|Adduri, Raju\|Gowrishankar, Swarnalata\|Bashyam, Leena\|Chaudhary, Ajay\|Vamsy, Mohana\|Patnaik, Sujith\|Srinivasulu, Mukta\|Sastry, Regulagadda\|Rao, Subramanyeshwar\|Vasala, Anjayneyulu\|Kalidindi, NarasimhaRaju\|Pollack, Jon
PMID:	23168910

1794.
Journal:	Am J Clin Oncol. 2014 Apr;37(2):117-21.
Title:	A prospective pilot study of target-guided personalized chemotherapy with intensity-modulated radiotherapy in patients with early rectal cancer.
Author:	Cubillo, Antonio\|Hernando-Requejo, Ovidio\|Garcia-Garcia, Elena\|Rodriguez-Pascual, Jesus\|De Vicente, Emilio\|Morelli, Pia\|Rubio, Carmen\|Lopez-Rios, Fernando\|Muro, Avertano\|Lopez, Ulpiano\|Prados, Susana\|Quijano, Yolanda\|Hidalgo, Manuel
PMID:	23211222

1795.
Journal:	Int J Clin Oncol. 2014 Feb;19(1):113-20.
Title:	Degraded DNA may induce discordance of KRAS status between primary colorectal cancer and corresponding liver metastases.
Author:	Kaneko, Yuka\|Kuramochi, Hidekazu\|Nakajima, Go\|Inoue, Yuji\|Yamamoto, Masakazu
PMID:	23299277

1796.
Journal:	J Oncol Pharm Pract. 2014 Feb;20(1):11-28.
Title:	Predictive and prognostic biomarkers with therapeutic targets in breast, colorectal, and non-small cell lung cancers: a systemic review of current development, evidence, and recommendation.
Author:	Chung, Clement\|Christianson, Matthew
PMID:	23493335

1797.
Journal:	Oncogene. 2014 Mar 20;33(12):1590-600.
Title:	Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors.
Author:	Ducker, G S\|Atreya, C E\|Simko, J P\|Hom, Y K\|Matli, M R\|Benes, C H\|Hann, B\|Nakakura, E K\|Bergsland, E K\|Donner, D B\|Settleman, J\|Shokat, K M\|Warren, R S
PMID:	23542178

1798.
Journal:	Invest New Drugs. 2014 Feb;32(1):113-22.
Title:	Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients.
Author:	Rubinson, Douglas A\|Hochster, Howard S\|Ryan, David P\|Wolpin, Brian M\|McCleary, Nadine Jackson\|Abrams, Thomas A\|Chan, Jennifer A\|Iqbal, Syma\|Lenz, Heinz J\|Lim, Dean\|Rose, Jeffrey\|Bekaii-Saab, Tanios\|Chen, Helen X\|Fuchs, Charles S\|Ng, Kimmie
PMID:	23568716

1799.
Journal:	Target Oncol. 2014 Jun;9(2):171-5.
Title:	Is availability of anti-EGFR therapy for the colorectal adenocarcinomas showing fascin expression limited?
Author:	Kocer, Nazim Emrah\|Kayaselcuk, Fazilet
PMID:	23588415

1800.
Journal:	Surg Today. 2014 Apr;44(4):593-600.
Title:	MUTYH-associated colorectal cancer and adenomatous polyposis.
Author:	Yamaguchi, Satoru\|Ogata, Hideo\|Katsumata, Daisuke\|Nakajima, Masanobu\|Fujii, Takaaki\|Tsutsumi, Soichi\|Asao, Takayuki\|Sasaki, Kinro\|Kuwano, Hiroyuki\|Kato, Hiroyuki
PMID:	23605219

1801.
Journal:	PLoS One. 2013 Jun 3;8(6):e65117.
Title:	Prognostic significance of C-reactive protein polymorphism and KRAS/BRAF in synchronous liver metastasis from colorectal cancer.
Author:	Huang, Chi-Jung\|Teng, Hao-Wei\|Chien, Chih-Cheng\|Lin, Jen-Kou\|Yang, Shung-Haur
PMID:	23755178

1802.
Journal:	Oncogene. 2014 Jun 5;33(23):2949-55.
Title:	Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Author:	Ogino, S\|Lochhead, P\|Giovannucci, E\|Meyerhardt, J A\|Fuchs, C S\|Chan, A T
PMID:	23792451

1803.
Journal:	Mol Carcinog. 2014 Feb;53 Suppl 1:E140-50.
Title:	VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Wolff, Roger K
PMID:	23794399

1804.
Journal:	Mod Pathol. 2014 Jan;27(1):135-44.
Title:	Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.
Author:	Mesteri, Ildiko\|Bayer, Gunther\|Meyer, Jochen\|Capper, David\|Schoppmann, Sebastian F\|von Deimling, Andreas\|Birner, Peter
PMID:	23887306

1805.
Journal:	Dig Liver Dis. 2014 Feb;46(2):105-12.
Title:	Options for metastatic colorectal cancer beyond the second line of treatment.
Author:	Foubert, Fanny\|Matysiak-Budnik, Tamara\|Touchefeu, Yann
PMID:	23954144

1806.
Journal:	Pharmacogenomics J. 2014 Jun;14(3):256-62.
Title:	Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan.
Author:	Sebio, A\|Paez, D\|Salazar, J\|Berenguer-Llergo, A\|Pare-Brunet, L\|Lasa, A\|Del Rio, E\|Tobena, M\|Martin-Richard, M\|Baiget, M\|Barnadas, A
PMID:	23959273

1807.
Journal:	Tumour Biol. 2014 Jan;35(1):831-5.
Title:	A let-7 KRAS rs712 polymorphism increases colorectal cancer risk.
Author:	Pan, Xin-Min\|Sun, Rui-Fen\|Li, Zhao-Hui\|Guo, Xiao-Min\|Zhang, Zhen\|Qin, Hao-Jie\|Xu, Guo-Hui\|Gao, Lin-Bo
PMID:	23975373

1808.
Journal:	J Gastrointest Cancer. 2014 Mar;45(1):34-9.
Title:	Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer.
Author:	Russo, Andrea L\|Ryan, David P\|Borger, Darrell R\|Wo, Jennifer Y\|Szymonifka, Jackie\|Liang, Wen-Yih\|Kwak, Eunice L\|Blaszkowsky, Lawrence S\|Clark, Jeffrey W\|Allen, Jill N\|Zhu, Andrew X\|Berger, David L\|Cusack, James C\|Mamon, Harvey J\|Haigis, Kevin M\|Hong, Theo
PMID:	24006244

1809.
Journal:	J Clin Pathol. 2014 Jan;67(1):1-9.
Title:	KRAS testing in metastatic colorectal carcinoma: challenges, controversies, breakthroughs and beyond.
Author:	Malapelle, Umberto\|Carlomagno, Chiara\|de Luca, Caterina\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	24022727

1810.
Journal:	Cancer Lett. 2014 Feb 1;343(1):1-5.
Title:	Clinical relevance of KRAS mutations in codon 13: Where are we?
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	24051306

1811.
Journal:	Fam Cancer. 2014 Mar;13(1):109-19.
Title:	Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer.
Author:	Garre, Pilar\|Martin, Lorena\|Bando, Inmaculada\|Tosar, Alicia\|Llovet, Patricia\|Sanz, Julian\|Romero, Atocha\|de la Hoya, Miguel\|Diaz-Rubio, Eduardo\|Caldes, Trinidad
PMID:	24061861

1812.
Journal:	J Clin Pathol. 2014 Mar;67(3):198-203.
Title:	miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.
Author:	Pichler, Martin\|Winter, Elke\|Ress, Anna Lena\|Bauernhofer, Thomas\|Gerger, Armin\|Kiesslich, Tobias\|Lax, Sigurd\|Samonigg, Hellmut\|Hoefler, Gerald
PMID:	24098024

1813.
Journal:	Int J Cancer. 2014 May 1;134(9):2146-55.
Title:	KRAS mutation confers resistance to antibody-dependent cellular cytotoxicity of cetuximab against human colorectal cancer cells.
Author:	Nakadate, Yusuke\|Kodera, Yasuo\|Kitamura, Yuka\|Shirasawa, Senji\|Tachibana, Taro\|Tamura, Tomohide\|Koizumi, Fumiaki
PMID:	24136682

1814.
Journal:	Int J Colorectal Dis. 2014 Feb;29(2):201-8.
Title:	Brain metastases from colorectal cancer: main clinical factors conditioning outcome.
Author:	Magni, Elena\|Santoro, Luigi\|Ravenda, Paola S\|Leonardi, Maria C\|Bonomo, Guido\|Monfardini, Lorenzo\|Nole, Franco\|Zampino, Maria G
PMID:	24158623

1815.
Journal:	Cancer Discov. 2014 Jan;4(1):42-52.
Title:	mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Author:	Faber, Anthony C\|Coffee, Erin M\|Costa, Carlotta\|Dastur, Anahita\|Ebi, Hiromichi\|Hata, Aaron N\|Yeo, Alan T\|Edelman, Elena J\|Song, Youngchul\|Tam, Ah Ting\|Boisvert, Jessica L\|Milano, Randy J\|Roper, Jatin\|Kodack, David P\|Jain, Rakesh K\|Corcoran, Ryan B\|Rivera,
PMID:	24163374

1816.
Journal:	Int J Cancer. 2014 May 15;134(10):2342-51.
Title:	Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
Author:	Dawson, Heather\|Galvan, Jose A\|Helbling, Melina\|Muller, Dominique-Elisabeth\|Karamitopoulou, Eva\|Koelzer, Viktor H\|Economou, Mary\|Hammer, Caroline\|Lugli, Alessandro\|Zlobec, Inti
PMID:	24166180

1817.
Journal:	Clin Cancer Res. 2014 Jan 1;20(1):265-72.
Title:	Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Author:	Guinney, Justin\|Ferte, Charles\|Dry, Jonathan\|McEwen, Robert\|Manceau, Gilles\|Kao, K J\|Chang, Kai-Ming\|Bendtsen, Claus\|Hudson, Kevin\|Huang, Erich\|Dougherty, Brian\|Ducreux, Michel\|Soria, Jean-Charles\|Friend, Stephen\|Derry, Jonathan\|Laurent-Puig, Pierre
PMID:	24170544

1818.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G48-58.
Title:	FXR silencing in human colon cancer by DNA methylation and KRAS signaling.
Author:	Bailey, Ann M\|Zhan, Le\|Maru, Dipen\|Shureiqi, Imad\|Pickering, Curtis R\|Kiriakova, Galina\|Izzo, Julie\|He, Nan\|Wei, Caimiao\|Baladandayuthapani, Veerabhadran\|Liang, Han\|Kopetz, Scott\|Powis, Garth\|Guo, Grace L
PMID:	24177031

1819.
Journal:	Neoplasma. 2014;61(1):1-8.
Title:	The role of tumor markers and biomarkers in colorectal cancer.
Author:	Lech, G\|Slotwinski, R\|Krasnodebski, I W
PMID:	24195503

1820.
Journal:	Int J Biol Markers. 2014 Mar 24;29(1):e55-61.
Title:	A PNA-mediated clamping PCR for routine detection of KRAS mutations in colorectal carcinoma.
Author:	Messa, Francesca\|Tonissi, Federica\|Millo, Enrico\|Bracco, Enrico\|Ungari, Silvana\|Lattanzio, Laura\|Merlano, Marco\|Damonte, Gianluca\|Lo Nigro, Cristiana
PMID:	24242294

1821.
Journal:	Carcinogenesis. 2014 Apr;35(4):776-83.
Title:	Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Nojima, Masanori\|Ito, Miki\|Maruyama, Reo\|Yoshii, Shinji\|Naito, Takafumi\|Sukawa, Yasutaka\|Mikami, Masashi\|Sumioka, Wakana\|Yamamoto, Eiichiro\|Kurokawa, Sei\|Adachi, Yasushi\|Takahashi, Hiroaki\|Okuda, Hiroyuki\|Kusumi, Takay
PMID:	24242331

1822.
Journal:	Clin Oncol (R Coll Radiol). 2014 Mar;26(3):135-41.
Title:	Panitumumab monotherapy as a second-line treatment in metastasised colorectal cancer: a single centre experience.
Author:	van Hellemond, I E G\|Creemers, G J\|van Warmerdam, L J C\|de Jong, F A\|Koornstra, R H T
PMID:	24246276

1823.
Journal:	Cancer Chemother Pharmacol. 2014 Feb;73(2):429-33.
Title:	Pharmacokinetics of panitumumab in a patient with liver dysfunction: a case report.
Author:	Krens, L L\|Baas, J M\|de Jong, F A\|Guchelaar, H J\|Gelderblom, H
PMID:	24258455

1824.
Journal:	Int J Cancer. 2014 Jun 15;134(12):2820-8.
Title:	KRAS mutations and CDKN2A promoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer.
Author:	Kohonen-Corish, Maija R J\|Tseung, Jason\|Chan, Charles\|Currey, Nicola\|Dent, Owen F\|Clarke, Stephen\|Bokey, Les\|Chapuis, Pierre H
PMID:	24259266

1825.
Journal:	Eur J Cancer. 2014 Feb;50(3):496-505.
Title:	Open-label, multicentre expansion cohort to evaluate imgatuzumab in pre-treated patients with KRAS-mutant advanced colorectal carcinoma.
Author:	Delord, Jean-Pierre\|Tabernero, Josep\|Garcia-Carbonero, Rocio\|Cervantes, Andres\|Gomez-Roca, Carlos\|Berge, Yann\|Capdevila, Jaume\|Paz-Ares, Luis\|Roda, Desamparados\|Delmar, Paul\|Oppenheim, David\|Brossard, Sophia Soehrman\|Farzaneh, Farzin\|Manenti, Luigi\|Passio
PMID:	24262587

1826.
Journal:	Ann Surg Oncol. 2014 Mar;21(3):946-54.
Title:	EGFR, BRAF and KRAS status in patients undergoing pulmonary metastasectomy from primary colorectal carcinoma: a prospective follow-up study.
Author:	Schweiger, Thomas\|Hegedus, Balazs\|Nikolowsky, Christoph\|Hegedus, Zita\|Szirtes, Ildiko\|Mair, Roland\|Birner, Peter\|Dome, Balazs\|Lang, Gyorgy\|Klepetko, Walter\|Ankersmit, Hendrik Jan\|Hoetzenecker, Konrad
PMID:	24281417

1827.
Journal:	Hum Mutat. 2014 Feb;35(2):208-14.
Title:	Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.
Author:	Crowley, Emily Hannah\|Arena, Sabrina\|Lamba, Simona\|Di Nicolantonio, Federica\|Bardelli, Alberto
PMID:	24282149

1828.
Journal:	J Pathol. 2014 Mar;232(4):415-27.
Title:	MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2.
Author:	Liao, Wen-Ting\|Ye, Ya-Ping\|Zhang, Nian-Jie\|Li, Ting-Ting\|Wang, Shu-Yang\|Cui, Yan-Mei\|Qi, Lu\|Wu, Ping\|Jiao, Hong-Li\|Xie, Yi-Jun\|Zhang, Chi\|Wang, Jun-Xian\|Ding, Yan-Qing
PMID:	24293274

1829.
Journal:	J Pathol. 2014 May;233(1):27-38.
Title:	PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
Author:	Davies, Emma J\|Marsh Durban, Victoria\|Meniel, Valerie\|Williams, Geraint T\|Clarke, Alan R
PMID:	24293351

1830.
Journal:	Mol Cancer Res. 2014 Jan;12(1):111-8.
Title:	ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Author:	Aisner, Dara L\|Nguyen, Teresa T\|Paskulin, Diego D\|Le, Anh T\|Haney, Jerry\|Schulte, Nathan\|Chionh, Fiona\|Hardingham, Jenny\|Mariadason, John\|Tebbutt, Niall\|Doebele, Robert C\|Weickhardt, Andrew J\|Varella-Garcia, Marileila
PMID:	24296758

1831.
Journal:	Lung Cancer. 2014 Feb;83(2):163-7.
Title:	KRAS mutations in non-small-cell lung cancer and colorectal cancer: implications for EGFR-targeted therapies.
Author:	Maus, M K H\|Grimminger, P P\|Mack, P C\|Astrow, S H\|Stephens, C\|Zeger, G\|Hsiang, J\|Brabender, J\|Friedrich, M\|Alakus, H\|Holscher, A H\|Lara, P\|Danenberg, K D\|Lenz, H J\|Gandara, D R
PMID:	24331409

1832.
Journal:	Cancer Biol Ther. 2014 Mar 1;15(3):266-70.
Title:	Increase in antibody-dependent cellular cytotoxicity (ADCC) in a patient with advanced colorectal carcinoma carrying a KRAS mutation under lenalidomide therapy.
Author:	Gamerith, Gabriele\|Auer, Thomas\|Amann, Arno\|Putzer, Daniel\|Schenk, Bettina\|Kircher, Brigitte\|Hilbe, Wolfgang\|Zwierzina, Heinz\|Loeffler-Ragg, Judith
PMID:	24351336

1833.
Journal:	Hum Mutat. 2014 Mar;35(3):329-40.
Title:	Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.
Author:	Kosmidou, Vivian\|Oikonomou, Eftychia\|Vlassi, Margarita\|Avlonitis, Spyros\|Katseli, Anastasia\|Tsipras, Iraklis\|Mourtzoukou, Despina\|Kontogeorgos, Georgios\|Zografos, Georgios\|Pintzas, Alexander
PMID:	24352906

1834.
Journal:	Clin Gastroenterol Hepatol. 2014 Mar;12(3):377-81.
Title:	DNA testing and molecular screening for colon cancer.
Author:	Carethers, John M
PMID:	24355100

1835.
Journal:	Oncol Rep. 2014 Mar;31(3):1466-72.
Title:	The role of plasma cell-free DNA detection in predicting preoperative chemoradiotherapy response in rectal cancer patients.
Author:	Sun, W\|Sun, Y\|Zhu, M\|Wang, Z\|Zhang, H\|Xin, Y\|Jiang, G\|Guo, X\|Zhang, Z\|Liu, Y
PMID:	24378613

1836.
Journal:	Ann Oncol. 2014 Feb;25(2):404-8.
Title:	Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.
Author:	Pietrantonio, F\|Perrone, F\|de Braud, F\|Castano, A\|Maggi, C\|Bossi, I\|Gevorgyan, A\|Biondani, P\|Pacifici, M\|Busico, A\|Gariboldi, M\|Festinese, F\|Tamborini, E\|Di Bartolomeo, M
PMID:	24379162

1837.
Journal:	Cancer Res. 2014 Mar 1;74(5):1311-8.
Title:	Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
Author:	Tahara, Tomomitsu\|Yamamoto, Eiichiro\|Suzuki, Hiromu\|Maruyama, Reo\|Chung, Woonbok\|Garriga, Judith\|Jelinek, Jaroslav\|Yamano, Hiro-o\|Sugai, Tamotsu\|An, Byonggu\|Shureiqi, Imad\|Toyota, Minoru\|Kondo, Yutaka\|Estecio, Marcos R H\|Issa, Jean-Pierre J
PMID:	24385213

1838.
Journal:	Mol Biol Rep. 2014 Mar;41(3):1291-8.
Title:	Effect of BRAF V600E mutation on tumor response of anti-EGFR monoclonal antibodies for first-line metastatic colorectal cancer treatment: a meta-analysis of randomized studies.
Author:	Cui, Dandan\|Cao, Dan\|Yang, Yu\|Qiu, Meng\|Huang, Ying\|Yi, Cheng
PMID:	24390240

1839.
Journal:	Carcinogenesis. 2014 May;35(5):1032-8.
Title:	Dietary acrylamide intake and the risk of colorectal cancer with specific mutations in KRAS and APC.
Author:	Hogervorst, Janneke G F\|de Bruijn-Geraets, Daisy\|Schouten, Leo J\|van Engeland, Manon\|de Kok, Theo M C M\|Goldbohm, R Alexandra\|van den Brandt, Piet A\|Weijenberg, Matty P
PMID:	24398672

1840.
Journal:	Anticancer Res. 2014 Jan;34(1):423-34.
Title:	Targeted agents and oxaliplatin-containing regimens for the treatment of colon cancer.
Author:	Bonetti, Andrea\|Giuliani, Jacopo\|Muggia, Franco
PMID:	24403498

1841.
Journal:	Gan To Kagaku Ryoho. 2014 Jan;41(1):1-6.
Title:	[Clinical application of next-generation sequencing technologies to achieve cancer precision medicine].
Author:	Tsuchihara, Katsuya
PMID:	24423944

1842.
Journal:	Int J Clin Oncol. 2014 Apr;19(2):211-9.
Title:	Is biomarker research advancing in the era of personalized medicine for head and neck cancer?
Author:	Yokota, Tomoya
PMID:	24442754

1843.
Journal:	Mol Biol Rep. 2014 Mar;41(3):1807-13.
Title:	TP53 mutations in colorectal cancer from Tunisia: relationships with site of tumor origin, microsatellite instability and KRAS mutations.
Author:	Aissi, Sana\|Buisine, Marie-Pierre\|Zerimech, Farid\|Kourda, Nadia\|Moussa, Amel\|Manai, Mohamed\|Porchet, Nicole
PMID:	24443225

1844.
Journal:	Int J Exp Pathol. 2014 Feb;95(1):16-23.
Title:	DNA content analysis of colorectal cancer defines a distinct 'microsatellite and chromosome stable' group but does not predict response to radiotherapy.
Author:	Fadhil, Wakkas\|Kindle, Karin\|Jackson, Darryl\|Zaitoun, Abed\|Lane, Nina\|Robins, Adrian\|Ilyas, Mohammad
PMID:	24456329

1845.
Journal:	Digestion. 2014;89(1):18-23.
Title:	Biomarkers for predicting the efficacy of anti-epidermal growth factor receptor antibody in the treatment of colorectal cancer.
Author:	Okada, Yasuyuki\|Miyamoto, Hiroshi\|Goji, Takahiro\|Takayama, Tetsuji
PMID:	24458108

1846.
Journal:	PLoS One. 2014 Jan 20;9(1):e85659.
Title:	Detection of colorectal serrated polyps by stool DNA testing: comparison with fecal immunochemical testing for occult blood (FIT).
Author:	Heigh, Russell I\|Yab, Tracy C\|Taylor, William R\|Hussain, Fareeda T N\|Smyrk, Thomas C\|Mahoney, Douglas W\|Domanico, Michael J\|Berger, Barry M\|Lidgard, Graham P\|Ahlquist, David A
PMID:	24465639

1847.
Journal:	PLoS One. 2014 Jan 21;9(1):e86103.
Title:	p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line.
Author:	Organ, Shawna L\|Hai, Josephine\|Radulovich, Nikolina\|Marshall, Christopher B\|Leung, Lisa\|Sasazuki, Takehiko\|Shirasawa, Senji\|Zhu, Chang-Qi\|Navab, Roya\|Ikura, Mitsuhiko\|Tsao, Ming-Sound
PMID:	24465899

1848.
Journal:	Curr Cancer Drug Targets. 2014;14(2):217-24.
Title:	Cetuximab inhibits gastric cancer growth in vivo, independent of KRAS status.
Author:	Shi, Min\|Shi, Hailong\|Ji, Jun\|Cai, Qu\|Chen, Xuehua\|Yu, Yingyan\|Liu, Bingya\|Zhu, Zhenggang\|Zhang, Jun
PMID:	24467518

1849.
Journal:	Invest New Drugs. 2014 Jun;32(3):535-41.
Title:	Effect of simvastatin plus cetuximab/irinotecan for KRAS mutant colorectal cancer and predictive value of the RAS signature for treatment response to cetuximab.
Author:	Lee, Jeeyun\|Hong, Yong Sang\|Hong, Jung Yong\|Han, Se Won\|Kim, Tae Won\|Kang, Hye Jin\|Kim, Tae You\|Kim, Kyu-Pyo\|Kim, Suk Hyung\|Do, In-Gu\|Kim, Kyoung-Mee\|Sohn, Insuk\|Park, Se Hoon\|Park, Joon Oh\|Lim, Ho Yeong\|Cho, Yong Beom\|Lee, Woo Yong\|Yun, Seong Hyeon\|Kim,
PMID:	24468885

1850.
Journal:	J Natl Cancer Inst. 2014 Feb;106(2):djt444.
Title:	KRAS and cancer stem cells in APC-mutant colorectal cancer.
Author:	Fearon, Eric R\|Wicha, Max S
PMID:	24491303

1851.
Journal:	Acta Oncol. 2014 Jul;53(7):877-84.
Title:	The relationship between rash, tumour KRAS mutation status and clinical and quality of life outcomes in patients with advanced colorectal cancer treated with cetuximab in the NCIC CTG/AGITG CO.17.
Author:	Sommeijer, Dirkje W\|Karapetis, Christos S\|Zalcberg, John R\|Tu, Dongsheng\|Jonker, Derek J\|Simes, John\|Tebbutt, Niall\|Yip, Desmond\|Price, Timothy J\|O'Callaghan, Chris J
PMID:	24495042

1852.
Journal:	PLoS One. 2014 Jan 30;9(1):e87966.
Title:	GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers.
Author:	Fecteau, Ryan E\|Lutterbaugh, James\|Markowitz, Sanford D\|Willis, Joseph\|Guda, Kishore
PMID:	24498230

1853.
Journal:	Cancer Chemother Pharmacol. 2014 Apr;73(4):749-57.
Title:	Overexpression of MET is a new predictive marker for anti-EGFR therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	24500024

1854.
Journal:	Am J Surg Pathol. 2014 Jul;38(7):910-20.
Title:	SMARCB1 (INI1)-negative rhabdoid carcinomas of the gastrointestinal tract: clinicopathologic and molecular study of a highly aggressive variant with literature review.
Author:	Agaimy, Abbas\|Rau, Tilman T\|Hartmann, Arndt\|Stoehr, Robert
PMID:	24503755

1855.
Journal:	PLoS One. 2014 Feb 4;9(2):e86789.
Title:	Oxaliplatin-based chemotherapy is more beneficial in KRAS mutant than in KRAS wild-type metastatic colorectal cancer patients.
Author:	Lin, Yu-Lin\|Liang, Yi-Hsin\|Tsai, Jia-Huei\|Liau, Jau-Yu\|Liang, Jin-Tung\|Lin, Been-Ren\|Hung, Ji-Shiang\|Lin, Liang-In\|Tseng, Li-Hui\|Chang, Yih-Leong\|Yeh, Kun-Huei\|Cheng, Ann-Lii
PMID:	24505265

1856.
Journal:	Anticancer Res. 2014 Feb;34(2):613-21.
Title:	Melting curve analysis for mutations of EGFR and KRAS.
Author:	Furugaki, Koh\|Yasuno, Hideyuki\|Iwai, Toshiki\|Moriya, Yoichiro\|Harada, Naoki\|Fujimoto-Ouchi, Kaori
PMID:	24510990

1857.
Journal:	J Nucl Med. 2014 Mar;55(3):386-91.
Title:	Multifunctional imaging signature for V-KI-RAS2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations in colorectal cancer.
Author:	Miles, Kenneth A\|Ganeshan, Balaji\|Rodriguez-Justo, Manuel\|Goh, Vicky J\|Ziauddin, Zia\|Engledow, Alec\|Meagher, Marie\|Endozo, Raymondo\|Taylor, Stuart A\|Halligan, Stephen\|Ell, Peter J\|Groves, Ashley M
PMID:	24516257

1858.
Journal:	Epigenetics. 2014 May;9(5):738-46.
Title:	CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.
Author:	Sun, Lifeng\|Guzzetta, Angela A\|Fu, Tao\|Chen, Jinming\|Jeschke, Jana\|Kwak, Ruby\|Vatapalli, Rajita\|Baylin, Stephen B\|Iacobuzio-Donahue, Christine A\|Wolfgang, Christopher L\|Ahuja, Nita
PMID:	24518818

1859.
Journal:	Eur J Hum Genet. 2014 Nov;22(11):1334-7.
Title:	Biallelic MUTYH mutations can mimic Lynch syndrome.
Author:	Morak, Monika\|Heidenreich, Barbara\|Keller, Gisela\|Hampel, Heather\|Laner, Andreas\|de la Chapelle, Albert\|Holinski-Feder, Elke
PMID:	24518836

1860.
Journal:	Braz J Med Biol Res. 2014 Jan;47(1):35-41.
Title:	Spectrum of K ras mutations in Pakistani colorectal cancer patients.
Author:	Murtaza, B N\|Bibi, A\|Rashid, M U\|Khan, Y I\|Chaudri, M S\|Shakoori, A R
PMID:	24519090

1861.
Journal:	Int J Cancer. 2014 May 1;134(9):2041-50.
Title:	Adrenomedullin is a therapeutic target in colorectal cancer.
Author:	Wang, Liangjing\|Gala, Manish\|Yamamoto, Masayoshi\|Pino, Maria S\|Kikuchi, Hirotoshi\|Shue, Daniel S\|Shirasawa, Senji\|Austin, Thomas R\|Lynch, Maureen P\|Rueda, Bo R\|Zukerberg, Lawrence R\|Chung, Daniel C
PMID:	24519534

1862.
Journal:	Cancer Res Treat. 2014 Jan;46(1):48-54.
Title:	Dose KRAS Mutation Status Affect on the Effect of VEGF Therapy in Metastatic Colon Cancer Patients?
Author:	Kim, Seung Tae\|Park, Kyong Hwa\|Shin, Sang Won\|Kim, Yeul Hong
PMID:	24520223

1863.
Journal:	Cancer Biol Ther. 2014 May;15(5):496-503.
Title:	Circulating tumor cells: exploring intratumor heterogeneity of colorectal cancer.
Author:	Raimondi, Cristina\|Nicolazzo, Chiara\|Gradilone, Angela\|Giannini, Giuseppe\|De Falco, Elena\|Chimenti, Isotta\|Varriale, Elisa\|Hauch, Siegfried\|Plappert, Linda\|Cortesi, Enrico\|Gazzaniga, Paola
PMID:	24521660

1864.
Journal:	Curr Oncol. 2014 Feb;21(1):e151-4.
Title:	Anticancer activity of combination targeted therapy using cetuximab plus vemurafenib for refractory BRAF (V600E)-mutant metastatic colorectal carcinoma.
Author:	Connolly, K\|Brungs, D\|Szeto, E\|Epstein, R J
PMID:	24523613

1865.
Journal:	Gastroenterology. 2014 May;146(5):1301-12.e1-10.
Title:	PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.
Author:	Li, Xin\|Stevens, Payton D\|Liu, Jianyu\|Yang, Haihua\|Wang, Wei\|Wang, Chi\|Zeng, Zheng\|Schmidt, Micheal D\|Yang, Mike\|Lee, Eun Y\|Gao, Tianyan
PMID:	24530606

1866.
Journal:	Clin Chim Acta. 2014 Apr 20;431:211-20.
Title:	KRAS mutations: analytical considerations.
Author:	Herreros-Villanueva, Marta\|Chen, Chih-Chieh\|Yuan, Shyng-Shiou F\|Liu, Ta-Chih\|Er, Tze-Kiong
PMID:	24534449

1867.
Journal:	Br J Cancer. 2014 Mar 18;110(6):1606-13.
Title:	RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.
Author:	Deb, S\|Xu, H\|Tuynman, J\|George, J\|Yan, Y\|Li, J\|Ward, R L\|Mortensen, N\|Hawkins, N J\|McKay, M J\|Ramsay, R G\|Fox, S B
PMID:	24548858

1868.
Journal:	Sci Transl Med. 2014 Feb 19;6(224):224ra24.
Title:	Detection of circulating tumor DNA in early- and late-stage human malignancies.
Author:	Bettegowda, Chetan\|Sausen, Mark\|Leary, Rebecca J\|Kinde, Isaac\|Wang, Yuxuan\|Agrawal, Nishant\|Bartlett, Bjarne R\|Wang, Hao\|Luber, Brandon\|Alani, Rhoda M\|Antonarakis, Emmanuel S\|Azad, Nilofer S\|Bardelli, Alberto\|Brem, Henry\|Cameron, John L\|Lee, Clarence C\|Fe
PMID:	24553385

1869.
Journal:	Sci Transl Med. 2014 Feb 19;6(224):224ra26.
Title:	Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer.
Author:	Misale, Sandra\|Arena, Sabrina\|Lamba, Simona\|Siravegna, Giulia\|Lallo, Alice\|Hobor, Sebastijan\|Russo, Mariangela\|Buscarino, Michela\|Lazzari, Luca\|Sartore-Bianchi, Andrea\|Bencardino, Katia\|Amatu, Alessio\|Lauricella, Calogero\|Valtorta, Emanuele\|Siena, Salvato
PMID:	24553387

1870.
Journal:	Jpn J Clin Oncol. 2014 Apr;44(4):383-7.
Title:	A prospective observational study to examine the relationship between quality of life and adverse events of first-line chemotherapy plus cetuximab in patients with KRAS wild-type unresectable metastatic colorectal cancer: QUACK Trial.
Author:	Ooki, Akira\|Ando, Masahiko\|Sakamoto, Junichi\|Sato, Atushi\|Fujii, Hirofumi\|Yamaguchi, Kensei
PMID:	24558128

1871.
Journal:	Gastrointest Cancer Res. 2014 Jan;7(1):23-6.
Title:	KRAS G13D Mutation and Sensitivity to Cetuximab or Panitumumab in a Colorectal Cancer Cell Line Model.
Author:	Kumar, Shalini Sree\|Price, Timothy J\|Mohyieldin, Omar\|Borg, Matthew\|Townsend, Amanda\|Hardingham, Jennifer E
PMID:	24558511

1872.
Journal:	Pathol Res Pract. 2014 May;210(5):274-8.
Title:	EGFR, KRAS, BRAF-mutations and microsatellite instability are absent in goblet cell carcinoids of the appendix.
Author:	Dimmler, Arno\|Geddert, Helene\|Faller, Gerhard
PMID:	24560515

1873.
Journal:	J Clin Pathol. 2014 Jun;67(6):491-8.
Title:	Prevalence and molecular characterisation of the sessile serrated adenoma in a subset of the Chinese population.
Author:	Qiu, Ye\|Fu, Xiangsheng\|Zhang, Wei\|Xu, Yong\|Xiao, Lanyue\|Chen, Xia\|Shi, Lei\|Zhou, Xian\|Xia, Guodong\|Peng, Yan\|Deng, Mingming
PMID:	24570042

1874.
Journal:	Cancer Lett. 2014 Jun 1;347(2):204-11.
Title:	Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.
Author:	Roper, Jatin\|Sinnamon, Mark J\|Coffee, Erin M\|Belmont, Peter\|Keung, Lily\|Georgeon-Richard, Larissa\|Wang, Wei Vivian\|Faber, Anthony C\|Yun, Jihye\|Yilmaz, Omer H\|Bronson, Roderick T\|Martin, Eric S\|Tsichlis, Philip N\|Hung, Kenneth E
PMID:	24576621

1875.
Journal:	Eur J Cancer. 2014 May;50(8):1430-6.
Title:	RAS mutations and cetuximab in locally advanced rectal cancer: results of the EXPERT-C trial.
Author:	Sclafani, F\|Gonzalez, D\|Cunningham, D\|Hulkki Wilson, S\|Peckitt, C\|Giralt, J\|Glimelius, B\|Rosello Keranen, S\|Wotherspoon, A\|Brown, G\|Tait, D\|Oates, J\|Chau, I
PMID:	24582914

1876.
Journal:	PLoS One. 2014 Feb 19;9(2):e89388.
Title:	FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
Author:	Jardim, Denis L\|Wheler, Jennifer J\|Hess, Kenneth\|Tsimberidou, Apostolia M\|Zinner, Ralph\|Janku, Filip\|Subbiah, Vivek\|Naing, Aung\|Piha-Paul, Sarina A\|Westin, Shannon N\|Roy-Chowdhuri, Sinchita\|Meric-Bernstam, Funda\|Hong, David S
PMID:	24586741

1877.
Journal:	Int J Cancer. 2014 Oct 1;135(7):1586-95.
Title:	Methylation epigenotypes and genetic features in colorectal laterally spreading tumors.
Author:	Sakai, Eiji\|Ohata, Ken\|Chiba, Hideyuki\|Matsuhashi, Nobuyuki\|Doi, Noriteru\|Fukushima, Junichi\|Endo, Hiroki\|Takahashi, Hirokazu\|Tsuji, Shingo\|Yagi, Koichi\|Matsusaka, Keisuke\|Aburatani, Hiroyuki\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	24590867

1878.
Journal:	Exp Mol Pathol. 2014 Apr;96(2):257-60.
Title:	KRAS insertions in colorectal cancer: what do we know about unusual KRAS mutations?
Author:	de Macedo, Mariana Petaccia\|de Lima, Luiz Guilherme Cernaglia Aureliano\|Begnami, Maria Dirlei Ferreira de Souza\|de Melo, Fernanda Machado\|Andrade, Louise D Brot\|Lisboa, Bianca Cristina Garcia\|Soares, Luisa Martelli\|Soares, Fernando Augusto\|Carraro, Dirce
PMID:	24594115

1879.
Journal:	Virchows Arch. 2014 May;464(5):575-81.
Title:	Mutation status of somatic EGFR and KRAS genes in Chinese patients with prostate cancer (PCa).
Author:	Fu, Meng\|Zhang, Wei\|Shan, Ling\|Song, Jian\|Shang, Donghao\|Ying, Jianming\|Zhao, Jimao
PMID:	24595526

1880.
Journal:	J Cancer Res Clin Oncol. 2014 May;140(5):737-48.
Title:	EGFR gene gain and PTEN protein expression are favorable prognostic factors in patients with KRAS wild-type metastatic colorectal cancer treated with cetuximab.
Author:	Razis, Evangelia\|Pentheroudakis, George\|Rigakos, George\|Bobos, Mattheos\|Kouvatseas, George\|Tzaida, Olympia\|Makatsoris, Thomas\|Papakostas, Pavlos\|Bai, Maria\|Goussia, Anna\|Samantas, Epaminontas\|Papamichael, Demetrios\|Romanidou, Ourania\|Efstratiou, Ioannis\|T
PMID:	24595598

1881.
Journal:	Nihon Rinsho. 2014 Jan;72(1):29-34.
Title:	[Perspective of personalized (precise) cancer therapy based on predictive biomarkers].
Author:	Osera, Shozo\|Yoshino, Takayuki
PMID:	24597345

1882.
Journal:	Cancer Res. 2014 Mar 15;74(6):1694-704.
Title:	Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer.
Author:	Steinert, Gunnar\|Scholch, Sebastian\|Niemietz, Thomas\|Iwata, Naoki\|Garcia, Sebastian A\|Behrens, Bianca\|Voigt, Anita\|Kloor, Matthias\|Benner, Axel\|Bork, Ulrich\|Rahbari, Nuh N\|Buchler, Markus W\|Stoecklein, Nikolas H\|Weitz, Jurgen\|Koch, Moritz
PMID:	24599131

1883.
Journal:	PLoS One. 2014 Mar 5;9(3):e90459.
Title:	Comparative genomic analysis of primary and synchronous metastatic colorectal cancers.
Author:	Lee, Sun Young\|Haq, Farhan\|Kim, Deokhoon\|Jun, Cui\|Jo, Hui-Jong\|Ahn, Sung-Min\|Lee, Won-Suk
PMID:	24599305

1884.
Journal:	Mod Pathol. 2014 Oct;27(10):1375-85.
Title:	Traditional serrated adenoma has two pathways of neoplastic progression that are distinct from the sessile serrated pathway of colorectal carcinogenesis.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Lin, Yu-Lin\|Lin, Liang-In\|Cheng, Yi-Chen\|Cheng, Mei-Ling\|Jeng, Yung-Ming
PMID:	24603588

1885.
Journal:	J Gastroenterol Hepatol. 2014 Jun;29(6):1192-9.
Title:	Distinct profile of HIF1alpha, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.
Author:	Morimoto, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Murakami, Takashi\|Sakamoto, Naoto\|Yao, Takashi\|Watanabe, Sumio
PMID:	24612059

1886.
Journal:	BMC Genomics. 2014 Mar 13;15:190.
Title:	Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author:	Castle, John C\|Loewer, Martin\|Boegel, Sebastian\|de Graaf, Jos\|Bender, Christian\|Tadmor, Arbel D\|Boisguerin, Valesca\|Bukur, Thomas\|Sorn, Patrick\|Paret, Claudia\|Diken, Mustafa\|Kreiter, Sebastian\|Tureci, Ozlem\|Sahin, Ugur
PMID:	24621249

1887.
Journal:	Elife. 2014 Mar 12;3:e02313.
Title:	A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype.
Author:	Serra, Ryan W\|Fang, Minggang\|Park, Sung Mi\|Hutchinson, Lloyd\|Green, Michael R
PMID:	24623306

1888.
Journal:	Oncol Rep. 2014 May;31(5):2115-22.
Title:	Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer.
Author:	Seo, Yuki\|Ishii, Yoshiyuki\|Ochiai, Hiroki\|Fukuda, Kazumasa\|Akimoto, Shingo\|Hayashida, Tetsu\|Okabayashi, Koji\|Tsuruta, Masashi\|Hasegawa, Hirotoshi\|Kitagawa, Yuko
PMID:	24626880

1889.
Journal:	J Natl Cancer Inst. 2014 Apr;106(4):dju043.
Title:	Masking epistasis between MYC and TGF-beta pathways in antiangiogenesis-mediated colon cancer suppression.
Author:	Dews, Michael\|Tan, Grace S\|Hultine, Stacy\|Raman, Pichai\|Choi, Jaewoo\|Duperret, Elizabeth K\|Lawler, Jack\|Bass, Adam\|Thomas-Tikhonenko, Andrei
PMID:	24627270

1890.
Journal:	World J Gastroenterol. 2014 Mar 14;20(10):2634-40.
Title:	Serrated pathway in colorectal carcinogenesis.
Author:	Yamane, Leticia\|Scapulatempo-Neto, Cristovam\|Reis, Rui Manuel\|Guimaraes, Denise Peixoto
PMID:	24627599

1891.
Journal:	J Mol Diagn. 2014 May;16(3):371-7.
Title:	Higher quality of molecular testing, an unfulfilled priority: Results from external quality assessment for KRAS mutation testing in colorectal cancer.
Author:	Tembuyser, Lien\|Ligtenberg, Marjolijn J L\|Normanno, Nicola\|Delen, Sofie\|van Krieken, J Han\|Dequeker, Elisabeth M C
PMID:	24631467

1892.
Journal:	Cancer Lett. 2014 Jun 1;347(2):191-5.
Title:	Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
Author:	Byun, Alexander J\|Hung, Kenneth E\|Fleet, James C\|Bronson, Roderick T\|Mason, Joel B\|Garcia, Paloma E\|Crott, Jimmy W
PMID:	24632531

1893.
Journal:	Klin Onkol. 2014;27(1):38-44.
Title:	[Surgical treatment of metastases and its impact on prognosis in patients with metastatic colorectal carcinoma].
Author:	Sevcikova, K\|Usakova, V\|Bartosova, Z\|Sabol, M\|Ondrusova, M\|Ondrus, D\|Spanik, S
PMID:	24635436

1894.
Journal:	Pathobiology. 2014;81(3):133-7.
Title:	Analysis of KRAS mutations in cases of metastatic colorectal cancer at a single institution in Tochigi, Japan.
Author:	Saito, Natsuko\|Tomita, Shigeki\|Ichikawa, Kazuhito\|Mitomi, Hiroyuki\|Imura, Johji\|Fujimori, Takahiro
PMID:	24642668

1895.
Journal:	Cancer Biol Ther. 2014 Jun 1;15(6):768-76.
Title:	Characterization of rare transforming KRAS mutations in sporadic colorectal cancer.
Author:	Tong, Joanna H M\|Lung, Raymond W M\|Sin, Frankie M C\|Law, Peggy P Y\|Kang, Wei\|Chan, Anthony W H\|Ma, Brigette B Y\|Mak, Tony W C\|Ng, Simon S M\|To, Ka Fai
PMID:	24642870

1896.
Journal:	PLoS One. 2014 Mar 18;9(3):e91033.
Title:	Multiple sporadic colorectal cancers display a unique methylation phenotype.
Author:	Gonzalo, Victoria\|Lozano, Juan Jose\|Alonso-Espinaco, Virginia\|Moreira, Leticia\|Munoz, Jenifer\|Pellise, Maria\|Castellvi-Bel, Sergi\|Bessa, Xavier\|Andreu, Montserrat\|Xicola, Rosa M\|Llor, Xavier\|Ruiz-Ponte, Clara\|Carracedo, Angel\|Jover, Rodrigo\|Castells, Anto
PMID:	24643221

1897.
Journal:	N Engl J Med. 2014 Apr 3;370(14):1287-97.
Title:	Multitarget stool DNA testing for colorectal-cancer screening.
Author:	Imperiale, Thomas F\|Ransohoff, David F\|Itzkowitz, Steven H\|Levin, Theodore R\|Lavin, Philip\|Lidgard, Graham P\|Ahlquist, David A\|Berger, Barry M
PMID:	24645800

1898.
Journal:	ISRN Surg. 2014 Feb 4;2014:157586.
Title:	The Presence of Mutations in the K-RAS Gene Does Not Affect Survival after Resection of Pulmonary Metastases from Colorectal Cancer.
Author:	Zabaleta, Jon\|Aguinagalde, Borja\|Izquierdo, Jose M\|Bazterargui, Nerea\|Laguna, Stephany M\|Martin-Arruti, Maialen\|Lobo, Carmen\|Emparanza, Jose I
PMID:	24649376

1899.
Journal:	J Med Life. 2014 Mar 15;7(1):17-26. Epub 2014 Mar 25.
Title:	Translating clinical research of Molecular Biology into a personalized, multidisciplinary approach of colorectal cancer patients.
Author:	Strambu, V\|Garofil, D\|Pop, F\|Radu, P\|Bratucu, M\|Popa, F
PMID:	24653752

1900.
Journal:	Int J Cancer. 2014 Nov 1;135(9):2215-22.
Title:	Changes in mutational status during third-line treatment for metastatic colorectal cancer--results of consecutive measurement of cell free DNA, KRAS and BRAF in the plasma.
Author:	Spindler, Karen-Lise Garm\|Pallisgaard, Niels\|Andersen, Rikke Fredslund\|Jakobsen, Anders
PMID:	24659028

1901.
Journal:	J BUON. 2014 Jan-Mar;19(1):83-90.
Title:	Clinical benefit of cetuximab and prognostic value of cetuximab-related skin toxicity in metastatic colorectal cancer: a single institution analysis.
Author:	Cvetanovic, Ana\|Vrbic, Svetislav\|Filipovic, Sladjana\|Pejcic, Ivica\|Milenkovic, Dusan\|Zivkovic, Nikola\|Kostic, Milos\|Petkovic, Ivan
PMID:	24659647

1902.
Journal:	World J Gastroenterol. 2014 Mar 21;20(11):2979-94.
Title:	Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines.
Author:	Khan, Sajjad\|Cameron, Silke\|Blaschke, Martina\|Moriconi, Federico\|Naz, Naila\|Amanzada, Ahmad\|Ramadori, Giuliano\|Malik, Ihtzaz Ahmed
PMID:	24659889

1903.
Journal:	J Exp Med. 2014 Apr 7;211(4):613-21.
Title:	RNA editing in RHOQ promotes invasion potential in colorectal cancer.
Author:	Han, Sae-Won\|Kim, Hwang-Phill\|Shin, Jong-Yeon\|Jeong, Eun-Goo\|Lee, Won-Chul\|Kim, Keon Young\|Park, Sang Youn\|Lee, Dae-Won\|Won, Jae-Kyung\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Seo, Jeong-Sun\|Kim, Jong-Il\|Kim, Tae-You
PMID:	24663214

1904.
Journal:	Mol Diagn Ther. 2014 Aug;18(4):459-68.
Title:	Highly sensitive KRAS mutation detection from formalin-fixed paraffin-embedded biopsies and circulating tumour cells using wild-type blocking polymerase chain reaction and Sanger sequencing.
Author:	Huang, Meggie Mo Chao\|Leong, Sai Mun\|Chua, Hui Wen\|Tucker, Steven\|Cheong, Wai Chye\|Chiu, Lily\|Li, Mo-Huang\|Koay, Evelyn Siew-Chuan
PMID:	24664550

1905.
Journal:	Cancer Med. 2014 Jun;3(3):674-80.
Title:	Comparison of HER2 expression between primary colorectal cancer and their corresponding metastases.
Author:	Lee, Won-Suk\|Park, Yeon Ho\|Lee, Jung Nam\|Baek, Jeong-Heum\|Lee, Tae-Hoon\|Ha, Seung Yeon
PMID:	24668895

1906.
Journal:	BMC Gastroenterol. 2014 Mar 28;14:55.
Title:	DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.
Author:	Loh, Marie\|Liem, Natalia\|Vaithilingam, Aparna\|Lim, Pei Li\|Sapari, Nur Sabrina\|Elahi, Eiram\|Mok, Zuan Yu\|Cheng, Chee Leong\|Yan, Benedict\|Pang, Brendan\|Salto-Tellez, Manuel\|Yong, Wei Peng\|Iacopetta, Barry\|Soong, Richie
PMID:	24674026

1907.
Journal:	Tumori. 2014 Jan-Feb;100(1):75-9.
Title:	Clinico-pathological study of K-ras mutations in colorectal tumors in Saudi Arabia.
Author:	Zahrani, Ali\|Kandil, Magdy\|Badar, Talha\|Abdelsalam, Mahmoud\|Al-Faiar, Abdulla\|Ismail, Abdelsalam
PMID:	24675495

1908.
Journal:	PLoS Genet. 2014 Mar 27;10(3):e1004271.
Title:	Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
Author:	Mohan, Sumitra\|Heitzer, Ellen\|Ulz, Peter\|Lafer, Ingrid\|Lax, Sigurd\|Auer, Martina\|Pichler, Martin\|Gerger, Armin\|Eisner, Florian\|Hoefler, Gerald\|Bauernhofer, Thomas\|Geigl, Jochen B\|Speicher, Michael R
PMID:	24676216

1909.
Journal:	Cell Rep. 2014 Apr 10;7(1):86-93.
Title:	Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
Author:	Sun, Chong\|Hobor, Sebastijan\|Bertotti, Andrea\|Zecchin, Davide\|Huang, Sidong\|Galimi, Francesco\|Cottino, Francesca\|Prahallad, Anirudh\|Grernrum, Wipawadee\|Tzani, Anna\|Schlicker, Andreas\|Wessels, Lodewyk F A\|Smit, Egbert F\|Thunnissen, Erik\|Halonen, Pasi\|Lieft
PMID:	24685132

1910.
Journal:	Clin Chim Acta. 2014 Jun 10;433:284-9.
Title:	Comparison of KRAS mutation analysis of primary tumors and matched circulating cell-free DNA in plasmas of patients with colorectal cancer.
Author:	Kuo, Yung-Bin\|Chen, Jinn-Shiun\|Fan, Chung-Wei\|Li, Yi-Shuan\|Chan, Err-Cheng
PMID:	24685572

1911.
Journal:	PLoS One. 2014 Apr 1;9(4):e92147.
Title:	Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status.
Author:	Pietrantonio, Filippo\|Maggi, Claudia\|Di Bartolomeo, Maria\|Facciorusso, Maria Grazia\|Perrone, Federica\|Testi, Adele\|Iacovelli, Roberto\|Miceli, Rosalba\|Bossi, Ilaria\|Leone, Giorgia\|Milione, Massimo\|Pelosi, Giuseppe\|de Braud, Filippo
PMID:	24691006

1912.
Journal:	Nature. 2014 Apr 10;508(7495):222-7.
Title:	Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Author:	Huber, Kilian V M\|Salah, Eidarus\|Radic, Branka\|Gridling, Manuela\|Elkins, Jonathan M\|Stukalov, Alexey\|Jemth, Ann-Sofie\|Gokturk, Camilla\|Sanjiv, Kumar\|Stromberg, Kia\|Pham, Therese\|Berglund, Ulrika Warpman\|Colinge, Jacques\|Bennett, Keiryn L\|Loizou, Joanna I\|
PMID:	24695225

1913.
Journal:	Int J Clin Exp Pathol. 2014 Feb 15;7(3):1266-74. eCollection 2014.
Title:	Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases.
Author:	Wang, Cai-Xia\|Liu, Biao\|Wang, Yan-Fen\|Zhang, Ru-Song\|Yu, Bo\|Lu, Zhen-Feng\|Shi, Qun-Li\|Zhou, Xiao-Jun
PMID:	24696747

1914.
Journal:	Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title:	The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author:	Abdul-Jalil, Khairun I\|Sheehan, Katherine M\|Toomey, Sinead\|Schmid, Jasmin\|Prehn, Jochen\|O'Grady, Anthony\|Cummins, Robert\|O'Neill, Brian\|McNamara, Deborah A\|Deasy, Joseph\|Breathnach, Oscar\|Grogan, Liam\|Rogers, Ailin\|Doherty, Glen\|Winter, Des\|Ryan, John\|El-
PMID:	24700299

1915.
Journal:	Lancet Oncol. 2014 May;15(6):631-9.
Title:	Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial.
Author:	Wasan, Harpreet\|Meade, Angela M\|Adams, Richard\|Wilson, Richard\|Pugh, Cheryl\|Fisher, David\|Sydes, Benjamin\|Madi, Ayman\|Sizer, Bruce\|Lowdell, Charles\|Middleton, Gary\|Butler, Rachel\|Kaplan, Richard\|Maughan, Tim
PMID:	24703531

1916.
Journal:	Dig Dis Sci. 2014 Sep;59(9):2255-63.
Title:	Genetic mechanisms in interval colon cancers.
Author:	Richter, James M\|Pino, Maria Simona\|Austin, Thomas R\|Campbell, Emily\|Szymonifka, Jackie\|Russo, Andrea L\|Hong, Theodore S\|Borger, Darrell\|Iafrate, A John\|Chung, Daniel C
PMID:	24705641

1917.
Journal:	Cancer Causes Control. 2014 Jun;25(6):759-69.
Title:	Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.
Author:	Huhn, Stefanie\|Bevier, Melanie\|Pardini, Barbara\|Naccarati, Alessio\|Vodickova, Ludmila\|Novotny, Jan\|Vodicka, Pavel\|Hemminki, Kari\|Forsti, Asta
PMID:	24706189

1918.
Journal:	Oncologist. 2014 May;19(5):568-73.
Title:	Identification of clinically relevant molecular subtypes in colorectal cancer: the dawning of a new era.
Author:	Johnston, Patrick G
PMID:	24718513

1919.
Journal:	BMC Gastroenterol. 2014 Apr 10;14:73.
Title:	KRAS mutations: variable incidences in a Brazilian cohort of 8,234 metastatic colorectal cancer patients.
Author:	Gil Ferreira, Carlos\|Aran, Veronica\|Zalcberg-Renault, Ilana\|Victorino, Ana Paula\|Salem, Jonas H\|Bonamino, Martin H\|Vieira, Fernando M\|Zalis, Mariano
PMID:	24720724

1920.
Journal:	Clin Cancer Res. 2014 Jun 15;20(12):3319-27.
Title:	Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).
Author:	Sha, Dan\|Lee, Adam M\|Shi, Qian\|Alberts, Steven R\|Sargent, Daniel J\|Sinicrope, Frank A\|Diasio, Robert B
PMID:	24727325

1921.
Journal:	Prog Tumor Res. 2014;41:36-50.
Title:	Successes and limitations of targeted cancer therapy in colon cancer.
Author:	Kohne, Claus-Henning
PMID:	24727985

1922.
Journal:	Int J Colorectal Dis. 2014 Jun;29(6):663-71.
Title:	Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Author:	Drecoll, Enken\|Nitsche, Ulrich\|Bauer, Karina\|Berezowska, Sabina\|Slotta-Huspenina, Julia\|Rosenberg, Robert\|Langer, Rupert
PMID:	24733427

1923.
Journal:	Lancet Oncol. 2014 May;15(6):540-1.
Title:	Targeting EGFR in colorectal cancer: beyond KRAS exon 2.
Author:	Waddell, Tom
PMID:	24739895

1924.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2014 Feb;43(2):77-82.
Title:	[Comparative analysis of real-time quantitative PCR-Sanger sequencing method and TaqMan probe method for detection of KRAS/BRAF mutation in colorectal carcinomas].
Author:	Zhang, Xun\|Wang, Yuehua\|Gao, Ning\|Wang, Jinfen
PMID:	24742565

1925.
Journal:	Dis Model Mech. 2014 Jun;7(6):613-23.
Title:	Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.
Author:	Belmont, Peter J\|Budinska, Eva\|Jiang, Ping\|Sinnamon, Mark J\|Coffee, Erin\|Roper, Jatin\|Xie, Tao\|Rejto, Paul A\|Derkits, Sahra\|Sansom, Owen J\|Delorenzi, Mauro\|Tejpar, Sabine\|Hung, Kenneth E\|Martin, Eric S
PMID:	24742783

1926.
Journal:	Gan To Kagaku Ryoho. 2014 Mar;41(3):399-401.
Title:	[A case of curatively resected sigmoid colon cancer after mFOLFOX6 plus panitumumab neoadjuvant chemotherapy].
Author:	Yoshikawa, Kiyoshi\|Kuwata, Hirofumi\|Nakahata, Yoshikatsu
PMID:	24743293

1927.
Journal:	Mol Cancer Ther. 2014 Jun;13(6):1399-409.
Title:	Moguntinones--new selective inhibitors for the treatment of human colorectal cancer.
Author:	Maderer, Annett\|Plutizki, Stanislav\|Kramb, Jan-Peter\|Gopfert, Katrin\|Linnig, Monika\|Khillimberger, Katrin\|Ganser, Christopher\|Lauermann, Eva\|Dannhardt, Gerd\|Galle, Peter R\|Moehler, Markus
PMID:	24743703

1928.
Journal:	Br J Cancer. 2014 Apr 29;110(9):2178-86.
Title:	A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine?
Author:	Maughan, T S\|Meade, A M\|Adams, R A\|Richman, S D\|Butler, R\|Fisher, D\|Wilson, R H\|Jasani, B\|Taylor, G R\|Williams, G T\|Sampson, J R\|Seymour, M T\|Nichols, L L\|Kenny, S L\|Nelson, A\|Sampson, C M\|Hodgkinson, E\|Bridgewater, J A\|Furniss, D L\|Roy, R\|Pope, M J\|Pope,
PMID:	24743706

1929.
Journal:	Ann Thorac Cardiovasc Surg. 2014;20 Suppl:692-6.
Title:	Molecular analysis of liquid cytological samples collected by bronchoscopy with radial endobronchial ultrasonography and guide sheath.
Author:	Iwabu, Naomi\|Izumo, Takehiro\|Nakamura, Yukiko\|Chavez, Christine\|Tsuchida, Takaaki\|Sasada, Shinji
PMID:	24747549

1930.
Journal:	Rev Recent Clin Trials. 2014;9(1):8-12.
Title:	The Emerging Role of NRAS Mutations in Colorectal Cancer Patients Selected for Anti-EGFR Therapies.
Author:	Meriggi, Fausto\|Vermi, William\|Bertocchi, Paola\|Zaniboni, Alberto
PMID:	24758538

1931.
Journal:	Tumour Biol. 2014 Jul;35(7):7163-75.
Title:	Implication of K-ras and p53 in colorectal cancer carcinogenesis in Tunisian population cohort.
Author:	Ines, Chaar\|Donia, Ounissi\|Rahma, Boughriba\|Ben Ammar, Azza\|Sameh, Amara\|Khalfallah, Taher\|Abdelmajid, Ben Hmida\|Sabeh, Mzabi\|Saadia, Bouraoui
PMID:	24763823

1932.
Journal:	World J Gastroenterol. 2014 Apr 21;20(15):4370-6.
Title:	Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer.
Author:	Kim, Bun\|Park, Soo Jung\|Cheon, Jae Hee\|Kim, Tae Il\|Kim, Won Ho\|Hong, Sung Pil
PMID:	24764675

1933.
Journal:	Oncol Lett. 2014 May;7(5):1532-1536.
Title:	KRAS and BRAF genotyping of synchronous colorectal carcinomas.
Author:	Giannini, Riccardo\|Lupi, Cristiana\|Loupakis, Fotios\|Servadio, Adele\|Cremolini, Chiara\|Sensi, Elisa\|Chiarugi, Massimo\|Antoniotti, Carlotta\|Basolo, Fulvio\|Falcone, Alfredo\|Fontanini, Gabriella
PMID:	24765171

1934.
Journal:	PLoS One. 2014 Apr 25;9(4):e96420.
Title:	Real-time bidirectional pyrophosphorolysis-activated polymerization for quantitative detection of somatic mutations.
Author:	Song, Najie\|Zhong, Xueting\|Li, Qingge
PMID:	24769870

1935.
Journal:	Anticancer Res. 2014 May;34(5):2061-8.
Title:	Molecular biomarkers and classification models in the evaluation of the prognosis of colorectal cancer.
Author:	Sideris, Michail\|Papagrigoriadis, Savvas
PMID:	24778007

1936.
Journal:	Anticancer Res. 2014 May;34(5):2571-9.
Title:	Lack of association between KRAS mutations and 18F-FDG PET/CT in Caucasian metastatic colorectal cancer patients.
Author:	Krikelis, Dimitrios\|Skoura, Evangelia\|Kotoula, Vassiliki\|Rondogianni, Phivi\|Pianou, Nikoletta\|Samartzis, Alexandros\|Xanthakis, Ioannis\|Fountzilas, George\|Datseris, Ioannis E
PMID:	24778079

1937.
Journal:	Case Rep Pulmonol. 2014;2014:282196.
Title:	Intestinal type of lung adenocarcinoma in younger adults.
Author:	Stojsic, Jelena\|Kontic, Milica\|Subotic, Dragan\|Popovic, Marko\|Tomasevic, Dragana\|Lukic, Jelena
PMID:	24782938

1938.
Journal:	PLoS One. 2014 May 1;9(5):e94977.
Title:	Does KRAS testing in metastatic colorectal cancer impact overall survival? A comparative effectiveness study in a population-based sample.
Author:	Feigelson, Heather Spencer\|Zeng, Chan\|Pawloski, Pamala A\|Onitilo, Adedayo A\|Richards, C Sue\|Johnson, Monique A\|Kauffman, Tia L\|Webster, Jennifer\|Nyirenda, Carsie\|Alexander, Gwen L\|Hwang, Clara\|Cross, Deanna\|McCarty, Catherine A\|Davis, Robert L\|Schwarzkopf
PMID:	24788807

1939.
Journal:	Gastroenterology. 2014 Aug;147(2):418-29.e8.
Title:	Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer.
Author:	Luo, Yanxin\|Wong, Chao-Jen\|Kaz, Andrew M\|Dzieciatkowski, Slavomir\|Carter, Kelly T\|Morris, Shelli M\|Wang, Jianping\|Willis, Joseph E\|Makar, Karen W\|Ulrich, Cornelia M\|Lutterbaugh, James D\|Shrubsole, Martha J\|Zheng, Wei\|Markowitz, Sanford D\|Grady, William M
PMID:	24793120

1940.
Journal:	Angiogenesis. 2014 Oct;17(4):805-21.
Title:	The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status.
Author:	Garcia-Alfonso, Pilar\|Grande, Enrique\|Polo, Eduardo\|Afonso, Ruth\|Reina, Juan Jose\|Jorge, Monica\|Campos, Juan Manuel\|Martinez, Virginia\|Angeles, Cristina\|Montagut, Clara
PMID:	24793846

1941.
Journal:	Pathology. 2014 Jun;46(4):311-5.
Title:	BRAFV600E mutation analysis by immunohistochemistry in patients with thoracic metastases from colorectal cancer.
Author:	Ilie, Marius I\|Long-Mira, Elodie\|Hofman, Veronique\|Mouroux, Jerome\|Vignaud, Jean-Michel\|Gauchotte, Guillaume\|Begueret, Hugues\|Merlio, Jean-Philippe\|Emile, Jean-Francois\|Hebuterne, Xavier\|Hofman, Paul
PMID:	24798160

1942.
Journal:	Int J Cancer. 2014 Dec 15;135(12):2984-91.
Title:	Cell-free DNA in healthy individuals, noncancerous disease and strong prognostic value in colorectal cancer.
Author:	Spindler, Karen-Lise Garm\|Appelt, Ane L\|Pallisgaard, Niels\|Andersen, Rikke F\|Brandslund, Ivan\|Jakobsen, Anders
PMID:	24798213

1943.
Journal:	Oncotarget. 2014 May 15;5(9):2807-19.
Title:	Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan.
Author:	Maitra, Radhashree\|Seetharam, Raviraja\|Tesfa, Lydia\|Augustine, Titto A\|Klampfer, Lidija\|Coffey, Matthew C\|Mariadason, John M\|Goel, Sanjay
PMID:	24798549

1944.
Journal:	Future Oncol. 2014 Apr;10(5):713-23.
Title:	Pyrosequencing evaluation of low-frequency KRAS mutant alleles for EGF receptor therapy selection in metastatic colorectal carcinoma.
Author:	Natalicchio, Maria Iole\|Improta, Giuseppina\|Zupa, Angela\|Cursio, Olga Elisabetta\|Stampone, Emanuela\|Possidente, Luciana\|Teresa Gerardi, Assunta Maria\|Vita, Giulia\|Martini, Maurizio\|Cassano, Alessandra\|Piccoli, Claudia\|Romito, Sante\|Aieta, Michele\|Antonett
PMID:	24799053

1945.
Journal:	Br J Cancer. 2014 May 27;110(11):2728-37.
Title:	Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study.
Author:	Etienne-Grimaldi, M-C\|Mahamat, A\|Chazal, M\|Laurent-Puig, P\|Olschwang, S\|Gaub, M-P\|Formento, J-L\|Formento, P\|Sudaka, A\|Boige, V\|Abderrahim-Ferkoune, A\|Benchimol, D\|Andre, T\|Houry, S\|Faucheron, J-L\|Letoublon, C\|Gilly, F-N\|Delpero, J-R\|Lasser, P\|Pradere, B\|P
PMID:	24800948

1946.
Journal:	Oncol Rep. 2014 Jul;32(1):50-6.
Title:	Clinicopathological characteristics and prognostic impact of colorectal cancers with NRAS mutations.
Author:	Ogura, Toshiro\|Kakuta, Miho\|Yatsuoka, Toshimasa\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Yamaguchi, Kensei\|Tanabe, Minoru\|Tanaka, Yoichi\|Akagi, Kiwamu
PMID:	24806883

1947.
Journal:	Clin Cancer Res. 2014 Jul 15;20(14):3775-86.
Title:	Primary and acquired resistance of colorectal cancer cells to anti-EGFR antibodies converge on MEK/ERK pathway activation and can be overcome by combined MEK/EGFR inhibition.
Author:	Troiani, Teresa\|Napolitano, Stefania\|Vitagliano, Donata\|Morgillo, Floriana\|Capasso, Anna\|Sforza, Vincenzo\|Nappi, Anna\|Ciardiello, Davide\|Ciardiello, Fortunato\|Martinelli, Erika
PMID:	24812410

1948.
Journal:	Int J Surg Pathol. 2014 Sep;22(6):505-11.
Title:	Rectal site and suboptimal nodal yield predict systemic recurrence in resected colorectal carcinoma: a case-control study.
Author:	Hayes, Brian D\|O'Riordan, James M\|Stuart, Charlotte\|Muldoon, Cian
PMID:	24813440

1949.
Journal:	J Cancer Res Clin Oncol. 2014 Sep;140(9):1607-14.
Title:	Left-sided primary tumors are associated with favorable prognosis in patients with KRAS codon 12/13 wild-type metastatic colorectal cancer treated with cetuximab plus chemotherapy: an analysis of the AIO KRK-0104 trial.
Author:	von Einem, J C\|Heinemann, V\|von Weikersthal, L Fischer\|Vehling-Kaiser, U\|Stauch, M\|Hass, H G\|Decker, T\|Klein, S\|Held, S\|Jung, A\|Kirchner, T\|Haas, M\|Holch, J\|Michl, M\|Aubele, P\|Boeck, S\|Schulz, C\|Giessen, C\|Stintzing, S\|Modest, D P
PMID:	24816724

1950.
Journal:	Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36.
Title:	Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta.
Author:	Wiener, Zoltan\|Band, Arja M\|Kallio, Pauliina\|Hogstrom, Jenny\|Hyvonen, Ville\|Kaijalainen, Seppo\|Ritvos, Olli\|Haglund, Caj\|Kruuna, Olli\|Robine, Sylvie\|Louvard, Daniel\|Ben-Neriah, Yinon\|Alitalo, Kari
PMID:	24825889

1951.
Journal:	Am J Surg Pathol. 2014 Sep;38(9):1235-41.
Title:	Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach.
Author:	Lasota, Jerzy\|Kowalik, Artur\|Wasag, Bartosz\|Wang, Zeng-Feng\|Felisiak-Golabek, Anna\|Coates, Tiffany\|Kopczynski, Janusz\|Gozdz, Stanislaw\|Miettinen, Markku
PMID:	24832158

1952.
Journal:	Eur J Cancer. 2014 Jul;50(11):1973-81.
Title:	RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
Author:	Alonso-Espinaco, Virginia\|Cuatrecasas, Miriam\|Alonso, Vicente\|Escudero, Pilar\|Marmol, Maribel\|Horndler, Carlos\|Ortego, Javier\|Gallego, Rosa\|Codony-Servat, Jordi\|Garcia-Albeniz, Xabier\|Jares, Pedro\|Castells, Antoni\|Lozano, Juan Jose\|Rosell, Rafael\|Maurel,
PMID:	24833563

1953.
Journal:	J Clin Invest. 2014 Jun;124(6):2668-82.
Title:	Targeting CD137 enhances the efficacy of cetuximab.
Author:	Kohrt, Holbrook E\|Colevas, A Dimitrios\|Houot, Roch\|Weiskopf, Kipp\|Goldstein, Matthew J\|Lund, Peder\|Mueller, Antonia\|Sagiv-Barfi, Idit\|Marabelle, Aurelien\|Lira, Ruth\|Troutner, Emily\|Richards, Lori\|Rajapaska, Amanda\|Hebb, Jonathan\|Chester, Cariad\|Waller, Er
PMID:	24837434

1954.
Journal:	Oncol Rep. 2014 Jul;32(1):57-64.
Title:	Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation.
Author:	Kishiki, Tomokazu\|Ohnishi, Hiroaki\|Masaki, Tadahiko\|Ohtsuka, Kouki\|Ohkura, Yasuo\|Furuse, Jyunji\|Sugiyama, Masanori\|Watanabe, Takashi
PMID:	24839940

1955.
Journal:	Eur J Cancer. 2014 Jul;50(11):1964-72.
Title:	Comprehensive molecular characterisation of hereditary non-polyposis colorectal tumours with mismatch repair proficiency.
Author:	Bellido, Fernando\|Pineda, Marta\|Sanz-Pamplona, Rebeca\|Navarro, Matilde\|Nadal, Marga\|Lazaro, Conxi\|Blanco, Ignacio\|Moreno, Victor\|Capella, Gabriel\|Valle, Laura
PMID:	24841217

1956.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S680-6.
Title:	Clinical relevance of alterations in quantity and quality of plasma DNA in colorectal cancer patients: based on the mutation spectra detected in primary tumors.
Author:	Lin, Jen-Kou\|Lin, Pei-Ching\|Lin, Chien-Hsing\|Jiang, Jeng-Kai\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Chang, Shih-Ching
PMID:	24841357

1957.
Journal:	Expert Rev Mol Diagn. 2014 Jun;14(5):517-24.
Title:	A new generation of companion diagnostics: cobas BRAF, KRAS and EGFR mutation detection tests.
Author:	Angulo, Barbara\|Lopez-Rios, Fernando\|Gonzalez, David
PMID:	24844134

1958.
Journal:	PLoS One. 2014 May 21;9(5):e98059.
Title:	Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps.
Author:	Yamada, Atsushi\|Minamiguchi, Sachiko\|Sakai, Yoshiharu\|Horimatsu, Takahiro\|Muto, Manabu\|Chiba, Tsutomu\|Boland, C Richard\|Goel, Ajay
PMID:	24849572

1959.
Journal:	Tumori. 2014 Mar-Apr;100(2):115-21.
Title:	Circulating free DNA in a screening program for early colorectal cancer detection.
Author:	Perrone, Federica\|Lampis, Andrea\|Bertan, Claudia\|Verderio, Paolo\|Ciniselli, Chiara M\|Pizzamiglio, Sara\|Frattini, Milo\|Nucifora, Martina\|Molinari, Francesca\|Gallino, Gianfranco\|Gariboldi, Manuela\|Meroni, Emanuele\|Leo, Ermanno\|Pierotti, Marco A\|Pilotti, Sil
PMID:	24852853

1960.
Journal:	Tumori. 2014 Mar-Apr;100(2):122-7.
Title:	KRAS mutations and M2PK upregulation in stool samples from individuals with positive fecal occult blood tests screened for colorectal cancer.
Author:	Battaglia, Paolo\|Baritono, Elisabetta\|Remo, Andrea\|Vendraminelli, Roberto\|Conti, Antonio
PMID:	24852854

1961.
Journal:	Am Soc Clin Oncol Educ Book. 2014:91-9.
Title:	The evolution of our molecular understanding of colorectal cancer: what we are doing now, what the future holds, and how tumor profiling is just the beginning.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	24857065

1962.
Journal:	Gastroenterology. 2014 Sep;147(3):637-45.
Title:	CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.
Author:	Shiovitz, Stacey\|Bertagnolli, Monica M\|Renfro, Lindsay A\|Nam, Eunmi\|Foster, Nathan R\|Dzieciatkowski, Slavomir\|Luo, Yanxin\|Lao, Victoria Valinluck\|Monnat, Raymond J Jr\|Emond, Mary J\|Maizels, Nancy\|Niedzwiecki, Donna\|Goldberg, Richard M\|Saltz, Leonard B\|Ven
PMID:	24859205

1963.
Journal:	Mol Diagn Ther. 2014 Oct;18(5):559-66.
Title:	Impact of specific KRAS mutation in exon 2 on clinical outcome of chemotherapy- and radiotherapy-treated colorectal adenocarcinoma patients.
Author:	Roszkowski, Krzysztof\|Zurawski, Bogdan\|Jozwicki, Wojciech\|Basta, Pawel\|Lewandowska, Marzena Anna
PMID:	24859378

1964.
Journal:	Nat Med. 2014 Jul;20(7):769-77.
Title:	Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Author:	Li, Xingnan\|Nadauld, Lincoln\|Ootani, Akifumi\|Corney, David C\|Pai, Reetesh K\|Gevaert, Olivier\|Cantrell, Michael A\|Rack, Paul G\|Neal, James T\|Chan, Carol W-M\|Yeung, Trevor\|Gong, Xue\|Yuan, Jenny\|Wilhelmy, Julie\|Robine, Sylvie\|Attardi, Laura D\|Plevritis, Sylv
PMID:	24859528

1965.
Journal:	BMJ Open. 2014 May 23;4(5):e004652.
Title:	KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: a cohort study.
Author:	Negru, Serban\|Papadopoulou, Eirini\|Apessos, Angela\|Stanculeanu, Dana Lucia\|Ciuleanu, Eliade\|Volovat, Constantin\|Croitoru, Adina\|Kakolyris, Stylianos\|Aravantinos, Gerasimos\|Ziras, Nikolaos\|Athanasiadis, Elias\|Touroutoglou, Nikolaos\|Pavlidis, Nikolaos\|Kalof
PMID:	24859998

1966.
Journal:	Rev Med Chil. 2014 Jan;142(1):55-60.
Title:	[BRAF gene mutation in wild-type KRAS patients with colorectal cancers].
Author:	Roa, Ivan\|Game, Anakaren\|Bizama, Carolina\|Schalper, Kurt
PMID:	24861115

1967.
Journal:	Rev Gastroenterol Mex. 2014 Apr-Jun;79(2):79-89.
Title:	Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.
Author:	Palacio-Rua, K A\|Isaza-Jimenez, L F\|Ahumada-Rodriguez, E\|Muneton-Pena, C M
PMID:	24861525

1968.
Journal:	Med Oncol. 2014 Jul;31(7):16.
Title:	Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer.
Author:	Zhu, Kunli\|Yan, Hongjiang\|Wang, Renben\|Zhu, Hui\|Meng, Xiangjiao\|Xu, Xiaoqing\|Dou, Xue\|Chen, Dong
PMID:	24861917

1969.
Journal:	Cancer Sci. 2014 Aug;105(8):1002-7.
Title:	Clinical impact of c-MET expression and genetic mutational status in colorectal cancer patients after liver resection.
Author:	Shoji, Hirokazu\|Yamada, Yasuhide\|Taniguchi, Hirokazu\|Nagashima, Kengo\|Okita, Natsuko\|Takashima, Atsuo\|Honma, Yoshitaka\|Iwasa, Satoru\|Kato, Ken\|Hamaguchi, Tetsuya\|Shimada, Yasuhiro
PMID:	24863535

1970.
Journal:	Clin Chim Acta. 2014 Sep 25;436:169-75.
Title:	Detection of KRAS codon 12 and 13 mutations by mutant-enriched PCR assay.
Author:	Chang, Ya-Sian\|Er, Tze-Kiong\|Lu, Hsiu-Chin\|Yeh, Kun-Tu\|Chang, Jan-Gowth
PMID:	24863805

1971.
Journal:	Nat Cell Biol. 2014 Jul;16(7):685-94.
Title:	Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH.
Author:	Urosevic, Jelena\|Garcia-Albeniz, Xabier\|Planet, Evarist\|Real, Sebastian\|Cespedes, Maria Virtudes\|Guiu, Marc\|Fernandez, Esther\|Bellmunt, Anna\|Gawrzak, Sylwia\|Pavlovic, Milica\|Mangues, Ramon\|Dolado, Ignacio\|Barriga, Francisco M\|Nadal, Cristina\|Kemeny, Nancy
PMID:	24880666

1972.
Journal:	J Transl Med. 2014 May 26;12:147.
Title:	Detection of activated KRAS from cancer patient peripheral blood using a weighted enzymatic chip array.
Author:	Huang, Ming-Yii\|Liu, Hsueh-Chiao\|Yen, Li-Chen\|Chang, Jia-Yuan\|Huang, Jian-Jhang\|Wang, Jaw-Yuan\|Hsiao, Chao-Peng\|Lin, Shiu-Ru
PMID:	24884535

1973.
Journal:	Mol Cancer. 2014 May 31;13:135.
Title:	Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Author:	Imamura, Yu\|Lochhead, Paul\|Yamauchi, Mai\|Kuchiba, Aya\|Qian, Zhi Rong\|Liao, Xiaoyun\|Nishihara, Reiko\|Jung, Seungyoun\|Wu, Kana\|Nosho, Katsuhiko\|Wang, Yaoyu E\|Peng, Shouyong\|Bass, Adam J\|Haigis, Kevin M\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S\|O
PMID:	24885062

1974.
Journal:	Gene. 2014 Aug 10;546(2):263-70.
Title:	Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer.
Author:	Li, Wen-Liang\|Xiao, Mei-Sheng\|Zhang, Deng-Feng\|Yu, Dandan\|Yang, Run-Xiang\|Li, Xiao-Yan\|Yao, Yong-Gang
PMID:	24887488

1975.
Journal:	Cancer Med. 2014 Oct;3(5):1385-95.
Title:	Let-7 microRNA-binding-site polymorphism in the 3'UTR of KRAS and colorectal cancer outcome: a systematic review and meta-analysis.
Author:	Langevin, Scott M\|Christensen, Brock C
PMID:	24890702

1976.
Journal:	Mol Cancer. 2014 Jun 4;13:141.
Title:	Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Author:	Cho, Jeonghee\|Bass, Adam J\|Lawrence, Michael S\|Cibulskis, Kristian\|Cho, Ahye\|Lee, Shi-Nai\|Yamauchi, Mai\|Wagle, Nikhil\|Pochanard, Panisa\|Kim, Nayoung\|Park, Angela Kj\|Won, Jonghwa\|Hur, Hyung-Suk\|Greulich, Heidi\|Ogino, Shuji\|Sougnez, Carrie\|Voet, Douglas\|Tab
PMID:	24894453

1977.
Journal:	Carcinogenesis. 2014 Aug;35(8):1881-90.
Title:	Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
Author:	Zeineldin, Maged\|Miller, Matthew A\|Sullivan, Ruth\|Neufeld, Kristi L
PMID:	24894865

1978.
Journal:	Anal Quant Cytopathol Histpathol. 2014 Feb;36(1):23-31.
Title:	Correlation between the presence of KRAS mutation and the morphometric characteristics of colorectal carcinoma cell nuclei.
Author:	Greenberg, Ariel\|Hershkovitz, Dov\|Sabo, Edmond
PMID:	24902368

1979.
Journal:	Abdom Imaging. 2014 Dec;39(6):1261-6.
Title:	Relationships between KRAS mutation status and baseline radiographic distribution of disease in patients with stage IV colorectal cancer.
Author:	Rosenthal, Michael H\|Kim, Kyung Won\|Fuchs, Charles S\|Meyerhardt, Jeffrey A\|Ramaiya, Nikhil H
PMID:	24906690

1980.
Journal:	APMIS. 2014 Dec;122(12):1187-95.
Title:	Annexin A10 expression correlates with serrated pathway features in colorectal carcinoma with microsatellite instability.
Author:	Kim, Jung Ho\|Rhee, Ye-Young\|Kim, Kyung-Ju\|Cho, Nam-Yun\|Lee, Hye Seung\|Kang, Gyeong Hoon
PMID:	24909058

1981.
Journal:	Mol Cancer. 2014 Jun 9;13:145.
Title:	Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.
Author:	Steinestel, Konrad\|Bruderlein, Silke\|Lennerz, Jochen K\|Steinestel, Julie\|Kraft, Klaus\|Propper, Christian\|Meineke, Viktor\|Moller, Peter
PMID:	24913355

1982.
Journal:	Virchows Arch. 2014 Aug;465(2):155-63.
Title:	Invasion pattern and histologic features of tumor aggressiveness correlate with MMR protein expression, but are independent of activating KRAS and BRAF mutations in CRC.
Author:	Steinestel, Konrad\|Lennerz, Jochen K\|Eder, Stefan\|Kraft, Klaus\|Arndt, Annette
PMID:	24915895

1983.
Journal:	Cancer Chemother Pharmacol. 2014 Jul;74(1):1-13.
Title:	Anti-EGFR MoAb treatment in colorectal cancer: limitations, controversies, and contradictories.
Author:	Cheng, Lei\|Ren, Wei\|Xie, Li\|Li, Ming\|Liu, Jiang\|Hu, Jing\|Liu, Bao-Rui\|Qian, Xiao-Ping
PMID:	24916545

1984.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6429-38.
Title:	TGFalpha and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells.
Author:	Hobor, Sebastijan\|Van Emburgh, Beth O\|Crowley, Emily\|Misale, Sandra\|Di Nicolantonio, Federica\|Bardelli, Alberto
PMID:	24916700

1985.
Journal:	PLoS One. 2014 Jun 11;9(2):e98964.
Title:	Associations of anthropometric factors with KRAS and BRAF mutation status of primary colorectal cancer in men and women: a cohort study.
Author:	Brandstedt, Jenny\|Wangefjord, Sakarias\|Nodin, Bjorn\|Eberhard, Jakob\|Sundstrom, Magnus\|Manjer, Jonas\|Jirstrom, Karin
PMID:	24918610

1986.
Journal:	Cancer Epidemiol Biomarkers Prev. 2014 Aug;23(8):1628-37.
Title:	Predicted 25(OH)D score and colorectal cancer risk according to vitamin D receptor expression.
Author:	Jung, Seungyoun\|Qian, Zhi Rong\|Yamauchi, Mai\|Bertrand, Kimberly A\|Fitzgerald, Kathryn C\|Inamura, Kentaro\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Zhang, Xuehong\|Wang, Molin\|Smith-Warner, Stephanie A\|Wu, Kana\|Fuchs, Charles S\|Chan, Andrew T\|Giovannucci, Ed
PMID:	24920642

1987.
Journal:	J Natl Cancer Inst. 2014 Jun 12;106(7). pii: dju106.
Title:	Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147.
Author:	Gonsalves, Wilson I\|Mahoney, Michelle R\|Sargent, Daniel J\|Nelson, Garth D\|Alberts, Steven R\|Sinicrope, Frank A\|Goldberg, Richard M\|Limburg, Paul J\|Thibodeau, Stephen N\|Grothey, Axel\|Hubbard, Joleen M\|Chan, Emily\|Nair, Suresh\|Berenberg, Jeffrey L\|McWilliam
PMID:	24925349

1988.
Journal:	Clin Cancer Res. 2014 Jun 15;20(12):3261-71.
Title:	CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer.
Author:	Cleven, Arjen H G\|Derks, Sarah\|Draht, Muriel X G\|Smits, Kim M\|Melotte, Veerle\|Van Neste, Leander\|Tournier, Benjamin\|Jooste, Valerie\|Chapusot, Caroline\|Weijenberg, Matty P\|Herman, James G\|de Bruine, Adriaan P\|van Engeland, Manon
PMID:	24928946

1989.
Journal:	Cell Rep. 2014 Jun 26;7(6):1940-55.
Title:	ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer.
Author:	Van Schaeybroeck, Sandra\|Kalimutho, Murugan\|Dunne, Philip D\|Carson, Robbie\|Allen, Wendy\|Jithesh, Puthen V\|Redmond, Keara L\|Sasazuki, Takehiko\|Shirasawa, Senji\|Blayney, Jaine\|Michieli, Paolo\|Fenning, Cathy\|Lenz, Heinz-Josef\|Lawler, Mark\|Longley, Daniel B\|J
PMID:	24931611

1990.
Journal:	Case Rep Oncol. 2014 May 17;7(2):316-22.
Title:	Combination Chemotherapy of Azacitidine and Cetuximab for Therapy-Related Acute Myeloid Leukemia following Oxaliplatin for Metastatic Colorectal Cancer.
Author:	Hashimoto, Akari\|Takada, Kohichi\|Horiguchi, Hiroto\|Sato, Tsutomu\|Iyama, Satoshi\|Murase, Kazuyuki\|Kamihara, Yusuke\|Ono, Kaoru\|Tatekoshi, Ayumi\|Hayashi, Tsuyoshi\|Miyanishi, Koji\|Sato, Yasushi\|Furuhata, Tomohisa\|Kobune, Masayoshi\|Takimoto, Rishu\|Hirata, Koic
PMID:	24932174

1991.
Journal:	Oncol Lett. 2014 Jun;7(6):1761-1766.
Title:	'Druggable' alterations detected by Ion Torrent in metastatic colorectal cancer patients.
Author:	Fang, Weijia\|Radovich, Milan\|Zheng, Yulong\|Fu, Cai-Yun\|Zhao, Peng\|Mao, Chengyu\|Zheng, Yi\|Zheng, Shusen
PMID:	24932229

1992.
Journal:	Am J Gastroenterol. 2014 Aug;109(8):1205-14.
Title:	Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions.
Author:	Lochhead, Paul\|Chan, Andrew T\|Giovannucci, Edward\|Fuchs, Charles S\|Wu, Kana\|Nishihara, Reiko\|O'Brien, Michael\|Ogino, Shuji
PMID:	24935274

1993.
Journal:	PLoS One. 2014 Jun 18;9(6):e99590.
Title:	Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy.
Author:	Algars, Annika\|Avoranta, Tuulia\|Osterlund, Pia\|Lintunen, Minnamaija\|Sundstrom, Jari\|Jokilehto, Terhi\|Ristimaki, Ari\|Ristamaki, Raija\|Carpen, Olli
PMID:	24940619

1994.
Journal:	Ann Oncol. 2014 Sep;25(9):1756-61.
Title:	Clinical activity of FOLFIRI plus cetuximab according to extended gene mutation status by next-generation sequencing: findings from the CAPRI-GOIM trial.
Author:	Ciardiello, F\|Normanno, N\|Maiello, E\|Martinelli, E\|Troiani, T\|Pisconti, S\|Giuliani, F\|Barone, C\|Carteni, G\|Rachiglio, A M\|Montesarchio, V\|Tonini, G\|Rizzi, D\|Cinieri, S\|Bordonaro, R\|Febbraro, A\|De Vita, F\|Orditura, M\|Fenizia, F\|Lambiase, M\|Rinaldi, A\|Tatan
PMID:	24942275

1995.
Journal:	J Cancer Res Clin Oncol. 2014 Nov;140(11):1863-71.
Title:	The BRAF mutation is associated with the prognosis in colorectal cancer.
Author:	Ahn, Tae Sung\|Jeong, Dongjun\|Son, Myoung Won\|Jung, Haeil\|Park, Soyoung\|Kim, Hyungjoo\|Bae, Sang Byung\|Kim, Han Jo\|Jeon, Young-Woo\|Lee, Moon Soo\|Baek, Moo-Jun
PMID:	24942334

1996.
Journal:	BMC Med Genomics. 2014 Jun 18;7:36.
Title:	Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer.
Author:	Shanmugam, Vijayalakshmi\|Ramanathan, Ramesh K\|Lavender, Nicole A\|Sinari, Shripad\|Chadha, Manpreet\|Liang, Winnie S\|Kurdoglu, Ahmet\|Izatt, Tyler\|Christoforides, Alexis\|Benson, Hollie\|Phillips, Lori\|Baker, Angela\|Murray, Christopher\|Hostetter, Galen\|Von Hoff
PMID:	24943349

1997.
Journal:	World J Gastroenterol. 2014 Jun 14;20(22):6786-808.
Title:	Colorectal cancer: from prevention to personalized medicine.
Author:	Binefa, Gemma\|Rodriguez-Moranta, Francisco\|Teule, Alex\|Medina-Hayas, Manuel
PMID:	24944469

1998.
Journal:	Genome Med. 2014 May 29;6(5):43.
Title:	Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Author:	Alakus, Hakan\|Babicky, Michele L\|Ghosh, Pradipta\|Yost, Shawn\|Jepsen, Kristen\|Dai, Yang\|Arias, Angelo\|Samuels, Michael L\|Mose, Evangeline S\|Schwab, Richard B\|Peterson, Michael R\|Lowy, Andrew M\|Frazer, Kelly A\|Harismendy, Olivier
PMID:	24944587

1999.
Journal:	Clin Cancer Res. 2014 Aug 15;20(16):4251-61.
Title:	Phase I expansion and pharmacodynamic study of the oral MEK inhibitor RO4987655 (CH4987655) in selected patients with advanced cancer with RAS-RAF mutations.
Author:	Zimmer, Lisa\|Barlesi, Fabrice\|Martinez-Garcia, Maria\|Dieras, Veronique\|Schellens, Jan H M\|Spano, Jean-Philippe\|Middleton, Mark R\|Calvo, Emiliano\|Paz-Ares, Luiz\|Larkin, James\|Pacey, Simon\|Venturi, Miro\|Kraeber-Bodere, Francoise\|Tessier, Jean J L\|Eberhardt,
PMID:	24947927

2000.
Journal:	Eur J Cancer. 2014 Sep;50(13):2241-50.
Title:	Prevalence of germline MUTYH mutations among Lynch-like syndrome patients.
Author:	Castillejo, Adela\|Vargas, Gardenia\|Castillejo, Maria Isabel\|Navarro, Matilde\|Barbera, Victor Manuel\|Gonzalez, Sara\|Hernandez-Illan, Eva\|Brunet, Joan\|Ramon y Cajal, Teresa\|Balmana, Judith\|Oltra, Silvestre\|Iglesias, Silvia\|Velasco, Angela\|Solanes, Ares\|Camp
PMID:	24953332

2001.
Journal:	Cell. 2014 Jul 3;158(1):171-84.
Title:	KRAS and YAP1 converge to regulate EMT and tumor survival.
Author:	Shao, Diane D\|Xue, Wen\|Krall, Elsa B\|Bhutkar, Arjun\|Piccioni, Federica\|Wang, Xiaoxing\|Schinzel, Anna C\|Sood, Sabina\|Rosenbluh, Joseph\|Kim, Jong W\|Zwang, Yaara\|Roberts, Thomas M\|Root, David E\|Jacks, Tyler\|Hahn, William C
PMID:	24954536

2002.
Journal:	Chirurgia (Bucur). 2014 May-Jun;109(3):383-9.
Title:	Efficacy of cetuximab in metastatic colon cancer - case report.
Author:	Grigorean, V T\|Ciuhu, A N\|Rahnea Nita, G\|Strambu, V\|Straja, D N\|Popescu, M\|Sandu, A M\|Rahnea Nita, R A
PMID:	24956345

2003.
Journal:	J Natl Cancer Inst. 2014 Jun 23;106(7). pii: dju121.
Title:	TP53 mutational status and cetuximab benefit in rectal cancer: 5-year results of the EXPERT-C trial.
Author:	Sclafani, Francesco\|Gonzalez, David\|Cunningham, David\|Hulkki Wilson, Sanna\|Peckitt, Clare\|Tabernero, Josep\|Glimelius, Bengt\|Cervantes, Andres\|Dewdney, Alice\|Wotherspoon, Andrew\|Brown, Gina\|Tait, Diana\|Oates, Jacqueline\|Chau, Ian
PMID:	24957073

2004.
Journal:	Br J Cancer. 2014 Jul 29;111(3):430-6.
Title:	Phase II study of gemcitabine, oxaliplatin in combination with panitumumab in KRAS wild-type unresectable or metastatic biliary tract and gallbladder cancer.
Author:	Hezel, A F\|Noel, M S\|Allen, J N\|Abrams, T A\|Yurgelun, M\|Faris, J E\|Goyal, L\|Clark, J W\|Blaszkowsky, L S\|Murphy, J E\|Zheng, H\|Khorana, A A\|Connolly, G C\|Hyrien, O\|Baran, A\|Herr, M\|Ng, K\|Sheehan, S\|Harris, D J\|Regan, E\|Borger, D R\|Iafrate, A J\|Fuchs, C\|Ryan
PMID:	24960403

2005.
Journal:	J Formos Med Assoc. 2014 Jul;113(7):417-21.
Title:	Hyperplastic polyps identified during screening endoscopy: reevaluated by histological examinations and genetic alterations.
Author:	Lin, Yang-Chao\|Chiu, Han-Mo\|Lee, Yi-Chia\|Shun, Chia-Tung\|Wang, Hsiu-Po\|Wu, Ming-Shiang
PMID:	24961182

2006.
Journal:	Oncotarget. 2014 Jun 30;5(12):4492-503.
Title:	Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
Author:	Agyeman, Akwasi\|Jha, Babal K\|Mazumdar, Tapati\|Houghton, Janet A
PMID:	24962990

2007.
Journal:	J Surg Oncol. 2014 Sep;110(4):451-7.
Title:	The prognostic role of microsatellite instability, codon-specific KRAS, and BRAF mutations in colon cancer.
Author:	Lin, Chun-Chi\|Lin, Jen-Kou\|Lin, Tzu-Chen\|Chen, Wei-Shone\|Yang, Shung-Haur\|Wang, Huann-Sheng\|Lan, Yuan-Tzu\|Jiang, Jeng-Kai\|Yang, Muh-Hwa\|Chang, Shih-Ching
PMID:	24964758

2008.
Journal:	BMC Cancer. 2014 Jun 25;14:466.
Title:	DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.
Author:	Muto, Yuta\|Maeda, Takafumi\|Suzuki, Koichi\|Kato, Takaharu\|Watanabe, Fumiaki\|Kamiyama, Hidenori\|Saito, Masaaki\|Koizumi, Kei\|Miyaki, Yuichiro\|Konishi, Fumio\|Alonso, Sergio\|Perucho, Manuel\|Rikiyama, Toshiki
PMID:	24964857

2009.
Journal:	Tumour Biol. 2014 Oct;35(10):9639-47.
Title:	Decreasing relapse in colorectal cancer patients treated with cetuximab by using the activating KRAS detection chip.
Author:	Huang, Ming-Yii\|Liu, Hsueh-Chiao\|Yen, Li-Chen\|Chang, Jia-Yuan\|Huang, Jian-Jhang\|Wang, Jaw-Yuan\|Lin, Shiu-Ru
PMID:	24964961

2010.
Journal:	Oncotarget. 2014 Jul 15;5(13):5138-52.
Title:	ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
Author:	Lee, Hyunji\|Lee, Hyunjung\|Chin, Hyunjung\|Kim, Kyoungmi\|Lee, Daekee
PMID:	24970817

2011.
Journal:	Clin Nucl Med. 2014 Aug;39(8):685-9.
Title:	Correlation between PET/CT parameters and KRAS expression in colorectal cancer.
Author:	Chen, Shang-Wen\|Chiang, Hua-Che\|Chen, William Tzu-Liang\|Hsieh, Te-Chun\|Yen, Kuo-Yang\|Chiang, Shu-Fen\|Kao, Chia-Hung
PMID:	24978328

2012.
Journal:	Int J Oncol. 2014 Sep;45(3):1167-74.
Title:	Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations.
Author:	Chevrier, Sandy\|Arnould, Laurent\|Ghiringhelli, Francois\|Coudert, Bruno\|Fumoleau, Pierre\|Boidot, Romain
PMID:	24990411

2013.
Journal:	J Clin Pathol. 2014 Sep;67(9):751-7.
Title:	RAS testing of colorectal carcinoma-a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group.
Author:	Wong, Newton A C S\|Gonzalez, David\|Salto-Tellez, Manuel\|Butler, Rachel\|Diaz-Cano, Salvador J\|Ilyas, Mohammad\|Newman, William\|Shaw, Emily\|Taniere, Philippe\|Walsh, Shaun V
PMID:	24996433

2014.
Journal:	Hum Pathol. 2014 Sep;45(9):1866-71.
Title:	Adenoma and carcinoma components in colonic tumors show discordance for KRAS mutation.
Author:	Hershkovitz, Dov\|Simon, Einav\|Bick, Tova\|Prinz, Elad\|Noy, Shawna\|Sabo, Edmond\|Ben-Izhak, Ofer\|Vieth, Michael
PMID:	24998492

2015.
Journal:	J Clin Pathol. 2014 Sep;67(9):764-7.
Title:	Comparison of KRAS mutation analysis of colorectal cancer samples by standard testing and next-generation sequencing.
Author:	Kothari, Nishi\|Schell, Michael J\|Teer, Jamie K\|Yeatman, Timothy\|Shibata, David\|Kim, Richard
PMID:	25004944

2016.
Journal:	Mol Cancer. 2014 Jul 8;13:168.
Title:	A very low incidence of BRAF mutations in Middle Eastern colorectal carcinoma.
Author:	Siraj, Abdul K\|Bu, Rong\|Prabhakaran, Sarita\|Bavi, Prashant\|Beg, Shaham\|Al Hazmi, Mohsen\|Al-Rasheed, Maha\|Alobaisi, Khadija\|Al-Dayel, Fouad\|AlManea, Hadeel\|Al-Sanea, Nasser\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	25005754

2017.
Journal:	Ann Oncol. 2014 Oct;25(10):2008-14.
Title:	Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer.
Author:	Morris, V K\|Lucas, F A San\|Overman, M J\|Eng, C\|Morelli, M P\|Jiang, Z-Q\|Luthra, R\|Meric-Bernstam, F\|Maru, D\|Scheet, P\|Kopetz, S\|Vilar, E
PMID:	25009008

2018.
Journal:	PLoS One. 2014 Jul 10;9(7):e101957.
Title:	SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer.
Author:	Lundberg, Ida V\|Lofgren Burstrom, Anna\|Edin, Sofia\|Eklof, Vincy\|Oberg, Ake\|Stenling, Roger\|Palmqvist, Richard\|Wikberg, Maria L
PMID:	25010701

2019.
Journal:	Clin Cancer Res. 2014 Sep 15;20(18):4962-70.
Title:	Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study.
Author:	Xicola, Rosa M\|Gagnon, Molly\|Clark, Julia R\|Carroll, Timothy\|Gao, Weihua\|Fernandez, Christian\|Mijic, Dragana\|Rawson, James B\|Janoski, Ashley\|Pusatcioglu, Cenk K\|Rajaram, Priyanka\|Gluskin, Adam B\|Regan, Maureen\|Chaudhry, Vivek\|Abcarian, Herand\|Blumetti, Je
PMID:	25013126

2020.
Journal:	Int J Oncol. 2014 Oct;45(4):1556-64.
Title:	An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations.
Author:	Liu, Yuliang\|Gudnason, Haukur\|Li, Yi-Ping\|Bang, Dang Duong\|Wolff, Anders
PMID:	25018048

2021.
Journal:	Ann Surg Oncol. 2014 Dec;21(13):4164-73.
Title:	SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features.
Author:	Li, Tingting\|Liao, Xiaoyun\|Lochhead, Paul\|Morikawa, Teppei\|Yamauchi, Mai\|Nishihara, Reiko\|Inamura, Kentaro\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Kuchiba, Aya\|Imamura, Yu\|Baba, Yoshifumi\|Shima, Kaori\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S
PMID:	25023548

2022.
Journal:	PLoS One. 2014 Jul 15;9(7):e99233.
Title:	The detection of the methylated Wif-1 gene is more accurate than a fecal occult blood test for colorectal cancer screening.
Author:	Amiot, Aurelien\|Mansour, Hicham\|Baumgaertner, Isabelle\|Delchier, Jean-Charles\|Tournigand, Christophe\|Furet, Jean-Pierre\|Carrau, Jean-Pierre\|Canoui-Poitrine, Florence\|Sobhani, Iradj
PMID:	25025467

2023.
Journal:	Inflamm Bowel Dis. 2014 Sep;20(9):1584-92.
Title:	Small bowel adenocarcinomas complicating Crohn's disease are associated with dysplasia: a pathological and molecular study.
Author:	Svrcek, Magali\|Piton, Gael\|Cosnes, Jacques\|Beaugerie, Laurent\|Vermeire, Severine\|Geboes, Karel\|Lemoine, Antoinette\|Cervera, Pascale\|El-Murr, Nizar\|Dumont, Sylvie\|Scriva, Aurelie\|Lascols, Olivier\|Ardizzone, Sandro\|Fociani, Paolo\|Savoye, Guillaume\|Le Pessot
PMID:	25029614

2024.
Journal:	Biomed Res Int. 2014;2014:591867.
Title:	Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.
Author:	Er, Tze-Kiong\|Chen, Chih-Chieh\|Bujanda, Luis\|Herreros-Villanueva, Marta
PMID:	25032217

2025.
Journal:	Oncol Rep. 2014 Oct;32(4):1419-26.
Title:	KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy.
Author:	Yamane, L S\|Scapulatempo-Neto, C\|Alvarenga, L\|Oliveira, C Z\|Berardinelli, G N\|Almodova, E\|Cunha, T R\|Fava, G\|Colaiacovo, W\|Melani, A\|Fregnani, J H\|Reis, R M\|Guimaraes, D P
PMID:	25050586

2026.
Journal:	Tumour Biol. 2014 Jul;35(7):6195-206.
Title:	Focus on genetic and epigenetic events of colorectal cancer pathogenesis: implications for molecular diagnosis.
Author:	Zoratto, Federica\|Rossi, Luigi\|Verrico, Monica\|Papa, Anselmo\|Basso, Enrico\|Zullo, Angelo\|Tomao, Luigi\|Romiti, Adriana\|Lo Russo, Giuseppe\|Tomao, Silverio
PMID:	25051912

2027.
Journal:	Br J Surg. 2014 Sep;101(10):1299-309.
Title:	Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation.
Author:	Leong, K J\|Beggs, A\|James, J\|Morton, D G\|Matthews, G M\|Bach, S P
PMID:	25052224

2028.
Journal:	J Oncol Pract. 2014 Sep;10(5):308-14.
Title:	Oncologists' response to new data regarding the use of epidermal growth factor receptor inhibitors in colorectal cancer.
Author:	Dotan, Efrat\|Li, Tianyu\|Hall, Michael J\|Meropol, Neal J\|Beck, J Robert\|Wong, Yu-Ning
PMID:	25052499

2029.
Journal:	Clin Colorectal Cancer. 2014 Sep;13(3):178-84.
Title:	Metastatic colorectal cancer treatment patterns according to kirsten rat sarcoma viral oncogene homolog genotype in U.S. Community-based oncology practices.
Author:	Landsman-Blumberg, Pamela B\|Carter, Gebra Cuyun\|Johnson, Barbara H\|Sedgley, Robert\|Nicol, Steven J\|Li, Li\|Shankaran, Veena
PMID:	25065655

2030.
Journal:	Microrna. 2014;2(3):219-24.
Title:	Mutations in MicroRNA Genes and Their Binding Sites are Infrequently Associated with Human Colorectal Cancer in the Kashmiri Population.
Author:	Maqbool, Raihana\|Ismail, Rehana\|Hussain, Mahboob- Ul-
PMID:	25069446

2031.
Journal:	Med Oncol. 2014 Sep;31(9):124.
Title:	Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of frequency, distribution pattern in Indian colorectal carcinoma.
Author:	Bisht, Swati\|Ahmad, Firoz\|Sawaimoon, Satyakam\|Bhatia, Simi\|Das, Bibhu Ranjan
PMID:	25073438

2032.
Journal:	Clin Colorectal Cancer. 2014 Sep;13(3):192-8.
Title:	Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies in older adults with metastatic colorectal cancer.
Author:	Dotan, Efrat\|Devarajan, Karthik\|D'Silva, A James\|Beck, Andrew\|Kloth, Dwight D\|Cohen, Steven J\|Denlinger, Crystal
PMID:	25074246

2033.
Journal:	Anticancer Res. 2014 Aug;34(8):4551-5.
Title:	Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture.
Author:	Tsunoda, Toshiyuki\|Ishikura, Shuhei\|Doi, Keiko\|Matsuzaki, Hiroshi\|Iwaihara, Yuri\|Shirasawa, Senji
PMID:	25075098

2034.
Journal:	Proteomics. 2014 Nov;14(21-22):2558-65.
Title:	Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency.
Author:	Leclerc, Daniel\|Dejgaard, Kurt\|Mazur, Alexander\|Deng, Liyuan\|Wu, Qing\|Nilsson, Tommy\|Rozen, Rima
PMID:	25081070

2035.
Journal:	J Gastrointest Oncol. 2014 Aug;5(4):265-9.
Title:	KRAS mutation profile differences between rectosigmoid localized adenocarcinomas and colon adenocarcinomas.
Author:	Baskin, Yasemin\|Dagdeviren, Yusuf Kagan\|Calibasi, Gizem\|Canda, Aras Emre\|Sarioglu, Sulen\|Ellidokuz, Hulya\|Oztop, Ilhan
PMID:	25083299

2036.
Journal:	PLoS One. 2014 Aug 1;9(8):e103159.
Title:	Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study.
Author:	Kirzin, Sylvain\|Marisa, Laetitia\|Guimbaud, Rosine\|De Reynies, Aurelien\|Legrain, Michele\|Laurent-Puig, Pierre\|Cordelier, Pierre\|Pradere, Bernard\|Bonnet, Delphine\|Meggetto, Fabienne\|Portier, Guillaume\|Brousset, Pierre\|Selves, Janick
PMID:	25083765

2037.
Journal:	Lancet Oncol. 2014 Sep;15(10):1065-75.
Title:	FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial.
Author:	Heinemann, Volker\|von Weikersthal, Ludwig Fischer\|Decker, Thomas\|Kiani, Alexander\|Vehling-Kaiser, Ursula\|Al-Batran, Salah-Eddin\|Heintges, Tobias\|Lerchenmuller, Christian\|Kahl, Christoph\|Seipelt, Gernot\|Kullmann, Frank\|Stauch, Martina\|Scheithauer, Werner\|H
PMID:	25088940

2038.
Journal:	PLoS One. 2014 Aug 4;9(8):e103551.
Title:	Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status.
Author:	Lee, Jeeyun\|Jain, Anjali\|Kim, Phillip\|Lee, Tani\|Kuller, Anne\|Princen, Fred\|In-GuDo\|Kim, Suk Hyeong\|Park, Joon Oh\|Park, Young Suk\|Singh, Sharat\|Kim, Hee Cheol
PMID:	25090459

2039.
Journal:	PLoS One. 2014 Aug 5;9(8):e103822.
Title:	Distinct molecular features of different macroscopic subtypes of colorectal neoplasms.
Author:	Konda, Kenichi\|Konishi, Kazuo\|Yamochi, Toshiko\|Ito, Yoichi M\|Nozawa, Hisako\|Tojo, Masayuki\|Shinmura, Kensuke\|Kogo, Mari\|Katagiri, Atsushi\|Kubota, Yutaro\|Muramoto, Takashi\|Yano, Yuichiro\|Kobayashi, Yoshiya\|Kihara, Toshihiro\|Tagawa, Teppei\|Makino, Reiko\|Tak
PMID:	25093594

2040.
Journal:	Cancer Discov. 2014 Oct;4(10):1182-1197.
Title:	Development of siRNA payloads to target KRAS-mutant cancer.
Author:	Yuan, Tina L\|Fellmann, Christof\|Lee, Chih-Shia\|Ritchie, Cayde D\|Thapar, Vishal\|Lee, Liam C\|Hsu, Dennis J\|Grace, Danielle\|Carver, Joseph O\|Zuber, Johannes\|Luo, Ji\|McCormick, Frank\|Lowe, Scott W
PMID:	25100204

2041.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):9732-43.
Title:	Beyond KRAS: Predictive factors of the efficacy of anti-EGFR monoclonal antibodies in the treatment of metastatic colorectal cancer.
Author:	De Stefano, Alfonso\|Carlomagno, Chiara
PMID:	25110411

2042.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):10050-61.
Title:	IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.
Author:	Naito, Takafumi\|Nosho, Katsuhiko\|Ito, Miki\|Igarashi, Hisayoshi\|Mitsuhashi, Kei\|Yoshii, Shinji\|Aoki, Hironori\|Nomura, Masafumi\|Sukawa, Yasutaka\|Yamamoto, Eiichiro\|Adachi, Yasushi\|Takahashi, Hiroaki\|Hosokawa, Masao\|Fujita, Masahiro\|Takenouchi, Toshinao\|Maru
PMID:	25110432

2043.
Journal:	Cancer Med. 2014 Dec;3(6):1527-38.
Title:	Mutations in POLE and survival of colorectal cancer patients--link to disease stage and treatment.
Author:	Stenzinger, Albrecht\|Pfarr, Nicole\|Endris, Volker\|Penzel, Roland\|Jansen, Lina\|Wolf, Thomas\|Herpel, Esther\|Warth, Arne\|Klauschen, Frederick\|Kloor, Matthias\|Roth, Wilfried\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael\|Weichert, W
PMID:	25124163

2044.
Journal:	Gan To Kagaku Ryoho. 2014 Jul;41(7):897-900.
Title:	[Successful treatment of advanced sigmoid colon cancer with liver metastases with cetuximab monotherapy as first-line treatment-a case report].
Author:	Harada, Kazuaki\|Hatanaka, Kazuteru\|Kinoshita, Kenji\|Kawamoto, Yasuyuki\|Yamato, Hiroaki\|Ogawa, Koji\|Yamamoto, Yoshiya\|Naruse, Hirohito
PMID:	25131880

2045.
Journal:	World J Gastroenterol. 2014 Aug 14;20(30):10425-31.
Title:	Personalizing medicine for metastatic colorectal cancer: current developments.
Author:	Marques, Andrea Marin\|Turner, Alice\|de Mello, Ramon Andrade
PMID:	25132758

2046.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6227-9.
Title:	Paracrine network: another step in the complexity of resistance to EGFR blockade?
Author:	Salazar, Ramon\|Capella, Gabriel\|Tabernero, Josep
PMID:	25139340

2047.
Journal:	Cancer. 2014 Dec 15;120(24):3965-71.
Title:	KRAS mutation influences recurrence patterns in patients undergoing hepatic resection of colorectal metastases.
Author:	Kemeny, Nancy E\|Chou, Joanne F\|Capanu, Marinela\|Gewirtz, Alexandra N\|Cercek, Andrea\|Kingham, T Peter\|Jarnagin, William R\|Fong, Yuman C\|DeMatteo, Ronald P\|Allen, Peter J\|Shia, Jinru\|Ang, Celina\|Vakiani, Efsevia\|D'Angelica, Michael I
PMID:	25155157

2048.
Journal:	Biomed Res Int. 2014;2014:629496.
Title:	Epithelial-mesenchymal transition and somatic alteration in colorectal cancer with and without peritoneal carcinomatosis.
Author:	Shelygin, Y A\|Pospekhova, N I\|Shubin, V P\|Kashnikov, V N\|Frolov, S A\|Sushkov, O I\|Achkasov, S I\|Tsukanov, A S
PMID:	25157365

2049.
Journal:	Int J Environ Res Public Health. 2014 Aug 25;11(9):8645-60.
Title:	Clinical and metabolic parameters in non-small cell lung carcinoma and colorectal cancer patients with and without KRAS mutations.
Author:	Yilmaz, Ahmet\|Mohamed, Nehad\|Patterson, Kara A\|Tang, Yan\|Shilo, Konstantin\|Villalona-Calero, Miguel A\|Davis, Michael E\|Zhou, Xiao-Ping\|Frankel, Wendy\|Otterson, Gregory A\|Zhao, Weiqiang
PMID:	25158139

2050.
Journal:	PLoS One. 2014 Aug 27;9(8):e105886.
Title:	Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy.
Author:	Zhou, Yinghui\|Rideout, William M 3rd\|Bressel, Angela\|Yalavarthi, Sireesha\|Zi, Tong\|Potz, Darren\|Farlow, Samuel\|Brodeur, Joelle\|Monti, Anthony\|Reddipalli, Shailaja\|Xiao, Qiurong\|Bottega, Steve\|Feng, Bin\|Chiu, M Isabel\|Bosenberg, Marcus\|Heyer, Joerg
PMID:	25162504

2051.
Journal:	Genome Biol. 2014 Aug 28;15(8):454.
Title:	Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Author:	Brannon, A Rose\|Vakiani, Efsevia\|Sylvester, Brooke E\|Scott, Sasinya N\|McDermott, Gregory\|Shah, Ronak H\|Kania, Krishan\|Viale, Agnes\|Oschwald, Dayna M\|Vacic, Vladimir\|Emde, Anne-Katrin\|Cercek, Andrea\|Yaeger, Rona\|Kemeny, Nancy E\|Saltz, Leonard B\|Shia, Jinru
PMID:	25164765

2052.
Journal:	Anal Biochem. 2014 Dec 1;466:51-8.
Title:	Electrochemical biosensor based on functional composite nanofibers for detection of K-ras gene via multiple signal amplification strategy.
Author:	Wang, Xiaoying\|Shu, Guofang\|Gao, Chanchan\|Yang, Yu\|Xu, Qian\|Tang, Meng
PMID:	25173509

2053.
Journal:	Clin Cancer Res. 2014 Sep 1;20(17):4499-4510.
Title:	A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.
Author:	Saridaki, Zenia\|Weidhaas, Joanne B\|Lenz, Heinz-Josef\|Laurent-Puig, Pierre\|Jacobs, Bart\|De Schutter, Jef\|De Roock, Wendy\|Salzman, David W\|Zhang, Wu\|Yang, Dongyun\|Pilati, Camilla\|Bouche, Olivier\|Piessevaux, Hubert\|Tejpar, Sabine
PMID:	25183481

2054.
Journal:	J Natl Cancer Inst. 2014 Sep 4;106(9). pii: dju195.
Title:	Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis.
Author:	Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Lochhead, Paul\|Qian, Zhi Rong\|Kuchiba, Aya\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Jung, Seungyoun\|Zhang, Xuehong\|Wu, Kana\|Cho, Eunyoung\|Chan, Andrew T\|Meyerhardt, Jeffrey A\|Harris, Curtis C\|Fuchs, Charles
PMID:	25190725

2055.
Journal:	Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13505-10.
Title:	Phospholipase Cdelta1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells.
Author:	Satow, Reiko\|Hirano, Tamaki\|Batori, Ryosuke\|Nakamura, Tomomi\|Murayama, Yumi\|Fukami, Kiyoko
PMID:	25197077

2056.
Journal:	Am Surg. 2014 Sep;80(9):873-7.
Title:	KRAS and PIK3CA mutation frequencies in patient-derived xenograft models of pancreatic and colorectal cancer are reflective of patient tumors and stable across passages.
Author:	Tignanelli, Christopher J\|Herrera Loeza, Silvia G\|Yeh, Jen Jen
PMID:	25197873

2057.
Journal:	PLoS One. 2014 Sep 8;9(9):e107165.
Title:	EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author:	Moller, Yvonne\|Siegemund, Martin\|Beyes, Sven\|Herr, Ricarda\|Lecis, Daniele\|Delia, Domenico\|Kontermann, Roland\|Brummer, Tilman\|Pfizenmaier, Klaus\|Olayioye, Monilola A
PMID:	25198428

2058.
Journal:	Oncol Lett. 2014 Oct;8(4):1422-1426.
Title:	KRAS mutational concordance between primary and metastatic colorectal adenocarcinoma.
Author:	Paliogiannis, Panagiotis\|Cossu, Antonio\|Tanda, Francesco\|Palmieri, Giuseppe\|Palomba, Grazia
PMID:	25202344

2059.
Journal:	Clin Colorectal Cancer. 2014 Sep;13(3):145-55.
Title:	Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.
Author:	Cheng, Ann-Lii\|Li, Jin\|Vaid, Ashok K\|Ma, Brigette Buig Yue\|Teh, Catherine\|Ahn, Joong B\|Bello, Maximino\|Charoentum, Chaiyut\|Chen, Li-Tzong\|de Lima Lopes, Gilberto Jr\|Ho, Gwo F\|Kong, Hwai L\|Lam, Ka O\|Liu, Tian S\|Park, Young S\|Sriuranpong, Virote\|Sudoyo, Aru
PMID:	25209093

2060.
Journal:	Onco Targets Ther. 2014 Aug 25;7:1487-96.
Title:	The involvement of Kras gene 3'-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis.
Author:	Ying, Hou-Qun\|Wang, Feng\|He, Bang-Shun\|Pan, Yu-Qin\|Gao, Tian-Yi\|Xu, Ye-Qiong\|Li, Rui\|Deng, Qi-Wen\|Sun, Hui-Lin\|Wang, Shu-Kui
PMID:	25210463

2061.
Journal:	Rev Gastroenterol Mex. 2014 Jul-Sep;79(3):166-70.
Title:	[Clinical relevance of the K-ras oncogene in colorectal cancer: experience in a Mexican population].
Author:	Cabrera-Mendoza, F\|Gainza-Lagunes, S\|Castaneda-Andrade, I\|Castro-Zarate, A
PMID:	25216999

2062.
Journal:	Oncotarget. 2014 Sep 15;5(17):7635-50.
Title:	Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells.
Author:	Hara, Toshifumi\|Jones, Matthew F\|Subramanian, Murugan\|Li, Xiao Ling\|Ou, Oliver\|Zhu, Yuelin\|Yang, Yuan\|Wakefield, Lalage M\|Hussain, S Perwez\|Gaedcke, Jochen\|Ried, Thomas\|Luo, Ji\|Caplen, Natasha J\|Lal, Ashish
PMID:	25245095

2063.
Journal:	Neoplasia. 2014 Sep;16(9):751-6.
Title:	Optimizing single agent panitumumab therapy in pre-treated advanced colorectal cancer.
Author:	Gasparini, Giampietro\|Buttitta, Fiamma\|D'Andrea, Mario Rosario\|Tumolo, Salvatore\|Buonadonna, Angela\|Pavese, Ida\|Cordio, Stefano\|De Tursi, Michele\|Mosconi, Stefania\|Stumbo, Luciano\|Felicioni, Lara\|Marchetti, Antonio
PMID:	25246275

2064.
Journal:	PLoS One. 2014 Sep 23;9(9):e108193.
Title:	3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.
Author:	McKinley, Eliot T\|Zhao, Ping\|Coffey, Robert J\|Washington, M Kay\|Manning, H Charles
PMID:	25247710

2065.
Journal:	PLoS One. 2014 Sep 26;9(9):e107926.
Title:	PCR-based assays versus direct sequencing for evaluating the effect of KRAS status on anti-EGFR treatment response in colorectal cancer patients: a systematic review and meta-analysis.
Author:	Shan, Lianfeng\|Li, Ming\|Ma, Jianzhong\|Zhang, Huidan
PMID:	25260023

2066.
Journal:	Clin Biochem. 2014 Dec;47(18):340-3.
Title:	High-throughput screening of extended RAS mutations based on high-resolution melting analysis for prediction of anti-EGFR treatment efficacy in colorectal carcinoma.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Sato, Kenichi\|Kitamura, Kouichi\|Nishimura, Motoi\|Sawai, Setsu\|Matsushita, Kazuyuki\|Suzuki, Kazufumi\|Ota, Satoshi\|Miyauchi, Hideaki\|Matsubara, Hisahiro\|Nakatani, Yukio\|Nomura, Fumio
PMID:	25262986

2067.
Journal:	Diagn Pathol. 2014 Sep 30;9:187.
Title:	KRAS and BRAF mutational status in colon cancer from Albanian patients.
Author:	Martinetti, Daniela\|Costanzo, Rosario\|Kadare, Shahin\|Alimehmeti, Mehdiu\|Colarossi, Cristina\|Canzonieri, Vincenzo\|Berretta, Massimiliano\|Memeo, Lorenzo
PMID:	25267307

2068.
Journal:	Anticancer Res. 2014 Oct;34(10):5517-21.
Title:	Mixed adenoneuroendocrine carcinoma of the colon: molecular pathogenesis and treatment.
Author:	Vanacker, Leen\|Smeets, Dominiek\|Hoorens, Anne\|Teugels, Erik\|Algaba, Roberto\|Dehou, Marie Francoise\|De Becker, Ann\|Lambrechts, Diether\|De Greve, Jacques
PMID:	25275049

2069.
Journal:	Carcinogenesis. 2014 Dec;35(12):2778-86.
Title:	Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
Author:	Saud, Shakir M\|Li, Weidong\|Morris, Nicole L\|Matter, Matthias S\|Colburn, Nancy H\|Kim, Young S\|Young, Matthew R
PMID:	25280562

2070.
Journal:	Mol Cancer Ther. 2014 Dec;13(12):2876-85.
Title:	Therapeutic silencing of KRAS using systemically delivered siRNAs.
Author:	Pecot, Chad V\|Wu, Sherry Y\|Bellister, Seth\|Filant, Justyna\|Rupaimoole, Rajesha\|Hisamatsu, Takeshi\|Bhattacharya, Rajat\|Maharaj, Anshumaan\|Azam, Salma\|Rodriguez-Aguayo, Cristian\|Nagaraja, Archana S\|Morelli, Maria Pia\|Gharpure, Kshipra M\|Waugh, Trent A\|Gonza
PMID:	25281617

2071.
Journal:	J Biomed Sci. 2014 Oct 5;21:95.
Title:	MicroRNA-5p and -3p co-expression and cross-targeting in colon cancer cells.
Author:	Choo, Kong Bung\|Soon, Yuen Loon\|Nguyen, Phan Nguyen Nhi\|Hiew, Michele Sook Yuin\|Huang, Chiu-Jung
PMID:	25287248

2072.
Journal:	Cancer Discov. 2014 Nov;4(11):1269-80.
Title:	Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution.
Author:	Misale, Sandra\|Di Nicolantonio, Federica\|Sartore-Bianchi, Andrea\|Siena, Salvatore\|Bardelli, Alberto
PMID:	25293556

2073.
Journal:	Biomed Res Int. 2014;2014:568693.
Title:	Biological and molecular effects of small molecule kinase inhibitors on low-passage human colorectal cancer cell lines.
Author:	Lange, Falko\|Franz, Benjamin\|Maletzki, Claudia\|Linnebacher, Michael\|Huhns, Maja\|Jaster, Robert
PMID:	25309914

2074.
Journal:	J Natl Compr Canc Netw. 2014 Oct;12(10):1433-42.
Title:	Predictive biomarkers for anti-epidermal growth factor receptor therapy: beyond KRAS testing.
Author:	Ashraf, Noman\|Kothari, Nishi\|Kim, Richard
PMID:	25313182

2075.
Journal:	Clin Cancer Res. 2014 Dec 15;20(24):6346-56.
Title:	Circulating pEGFR is a candidate response biomarker of cetuximab therapy in colorectal cancer.
Author:	Katsila, Theodora\|Juliachs, Merce\|Gregori, Josep\|Macarulla, Teresa\|Villarreal, Laura\|Bardelli, Alberto\|Torrance, Chris\|Elez, Elena\|Tabernero, Josep\|Villanueva, Josep
PMID:	25324142

2076.
Journal:	Tumour Biol. 2014 Dec;35(12):11851-4.
Title:	Somatic mutations of the HER2 in metastatic breast cancer.
Author:	Fang, Yi\|Jiang, Yanxia\|Wang, Xin\|Yang, Xue\|Gao, Yinqi\|Wang, Jing
PMID:	25326805

2077.
Journal:	Onco Targets Ther. 2014 Oct 4;7:1817-28.
Title:	Colorectal cancer in Chinese patients: current and emerging treatment options.
Author:	Li, Leung\|Ma, Brigette By
PMID:	25336973

2078.
Journal:	Int J Clin Exp Pathol. 2014 Aug 15;7(9):5927-39. eCollection 2014.
Title:	Comparison of neuroendocrine differentiation and KRAS/NRAS/BRAF/PIK3CA/TP53 mutation status in primary and metastatic colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Novy, Michael\|Oberkanins, Christian\|Xu, Li\|Li, Guojun\|Loland, Christiane\|Poetsch, Micaela
PMID:	25337237

2079.
Journal:	Cancer Manag Res. 2014 Oct 14;6:405-22.
Title:	MicroRNA dysregulation as a prognostic biomarker in colorectal cancer.
Author:	Dong, Yujuan\|Yu, Jun\|Ng, Simon Sm
PMID:	25342918

2080.
Journal:	BMC Cancer. 2014 Nov 3;14:802.
Title:	BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients.
Author:	Chen, Jing\|Guo, Fang\|Shi, Xin\|Zhang, Lihua\|Zhang, Aifeng\|Jin, Hui\|He, Youji
PMID:	25367198

2081.
Journal:	Anticancer Res. 2014 Nov;34(11):6767-73.
Title:	Preoperative treatment with capecitabine, cetuximab and radiotherapy for primary locally advanced rectal cancer--a phase II clinical trial.
Author:	Eisterer, Wolfgang\|De Vries, Alexander\|Ofner, Dietmar\|Rabl, Hans\|Koplmuller, Renate\|Greil, Richard\|Tschmelitsch, Joerg\|Schmid, Rainer\|Kapp, Karin\|Lukas, Peter\|Sedlmayer, Felix\|Hofler, Gerald\|Gnant, Michael\|Thaler, Josef
PMID:	25368289

2082.
Journal:	Drugs Today (Barc). 2014 Oct;50(10):679-90.
Title:	Panitumumab in the treatment of colon cancer: A biomarker dilemma.
Author:	Scott, A\|Messersmith, W A\|Jimeno, A\|Davies, S L
PMID:	25374966

2083.
Journal:	Neoplasia. 2014 Oct 23;16(10):814-23.
Title:	The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
Author:	Tanaka, Hiromi\|Beam, Matthew J\|Caruana, Kevin
PMID:	25379018

2084.
Journal:	Neoplasia. 2014 Oct 23;16(10):845-60.
Title:	Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.
Author:	Grasso, Silvina\|Tristante, Elena\|Saceda, Miguel\|Carbonell, Pablo\|Mayor-Lopez, Leticia\|Carballo-Santana, Mar\|Carrasco-Garcia, Estefania\|Rocamora-Reverte, Lourdes\|Garcia-Morales, Pilar\|Carballo, Fernando\|Ferragut, Jose A\|Martinez-Lacaci, Isabel
PMID:	25379021

2085.
Journal:	J Tissue Eng. 2014 Jul 17;5:2041731414544183.
Title:	The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer.
Author:	Magdeldin, Tarig\|Lopez-Davila, Victor\|Villemant, Cecile\|Cameron, Grant\|Drake, Rosemary\|Cheema, Umber\|Loizidou, Marilena
PMID:	25383169

2086.
Journal:	Curr Colorectal Cancer Rep. 2014 Sep 1;10(3):346-353.
Title:	Prognostic Impact of Deficient DNA Mismatch Repair and Mutations in KRAS, and BRAF(V600E) in Patients with Lymph Node-Positive Colon Cancer.
Author:	Zaanan, Aziz\|Bachet, Jean-Baptiste\|Andre, Thierry\|Sinicrope, Frank A
PMID:	25386108

2087.
Journal:	Sci Signal. 2014 Nov 11;7(351):ra107.
Title:	Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Author:	Belmont, Peter J\|Jiang, Ping\|McKee, Trevor D\|Xie, Tao\|Isaacson, Jason\|Baryla, Nicole E\|Roper, Jatin\|Sinnamon, Mark J\|Lee, Nathan V\|Kan, Julie L C\|Guicherit, Oivin\|Wouters, Bradly G\|O'Brien, Catherine A\|Shields, David\|Olson, Peter\|VanArsdale, Todd\|Weinrich
PMID:	25389372

2088.
Journal:	Appl Immunohistochem Mol Morphol. 2014 Nov-Dec;22(10):728-34.
Title:	LEF-1 is frequently expressed in colorectal carcinoma and not in other gastrointestinal tract adenocarcinomas: an immunohistochemical survey of 602 gastrointestinal tract neoplasms.
Author:	Kermanshahi, Taher R\|Jayachandran, Priya\|Chang, Daniel T\|Pai, Reet
PMID:	25394300

2089.
Journal:	PLoS One. 2014 Nov 17;9(11):e113037.
Title:	Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Author:	Pitts, Todd M\|Newton, Timothy P\|Bradshaw-Pierce, Erica L\|Addison, Rebecca\|Arcaroli, John J\|Klauck, Peter J\|Bagby, Stacey M\|Hyatt, Stephanie L\|Purkey, Alicia\|Tentler, John J\|Tan, Aik Choon\|Messersmith, Wells A\|Eckhardt, S Gail\|Leong, Stephen
PMID:	25401499

2090.
Journal:	PLoS One. 2014 Nov 20;9(11):e113350.
Title:	Novel KRAS gene mutations in sporadic colorectal cancer.
Author:	Naser, Walid M\|Shawarby, Mohamed A\|Al-Tamimi, Dalal M\|Seth, Arun\|Al-Quorain, Abdulaziz\|Nemer, Areej M Al\|Albagha, Omar M E
PMID:	25412182

2091.
Journal:	BMC Cancer. 2014 Nov 22;14:865.
Title:	Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRAS metastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study).
Author:	Fernandez-Plana, Julen\|Pericay, Carlos\|Quintero, Guillermo\|Alonso, Vicente\|Salud, Antonieta\|Mendez, Miguel\|Salgado, Mercedes\|Saigi, Eugeni\|Cirera, Luis
PMID:	25417182

2092.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Nov;17(11):1062-7.
Title:	[Application of molecular targeted agents in comprehensive treatment of gastrointestinal cancer].
Author:	Li, Jian\|Shen, Lin
PMID:	25421761

2093.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Nov;17(11):1081-6.
Title:	[Safety and efficacy analysis on modified FOLFOXIRI as first-line treatment for advanced colorectal cancer in China-single center experience].
Author:	Cai, Yue\|Hu, Huabin\|Wang, Wenjing\|Cao, Taiyuan\|Deng, Yanhong
PMID:	25421765

2094.
Journal:	Neoplasia. 2014 Nov 20;16(11):972-81.
Title:	E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts.
Author:	Wiegering, Armin\|Korb, Doreen\|Thalheimer, Andreas\|Kammerer, Ulrike\|Allmanritter, Jan\|Matthes, Niels\|Linnebacher, Michael\|Schlegel, Nicolas\|Klein, Ingo\|Ergun, Suleyman\|Germer, Christoph-Thomas\|Otto, Christoph
PMID:	25425971

2095.
Journal:	PLoS One. 2014 Nov 26;9(11):e113186.
Title:	c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.
Author:	Li, Yingbo\|Wang, Jinxi\|Gao, Xing\|Han, Weihua\|Zheng, Yongxiang\|Xu, Huan\|Zhang, Chuanling\|He, Qiuchen\|Zhang, Lihe\|Li, Zhongxin\|Zhou, Demin
PMID:	25427200

2096.
Journal:	Oncol Res Treat. 2014;37(11):646-52.
Title:	Efficacy of triplet combination chemotherapy with oxaliplatin, irinotecan and capecitabine (OCX) in metastatic colorectal cancer in relation to RAS/RAF mutation status: results of a retrospective analysis.
Author:	Brunner, Stefan\|von Moos, Roger\|Mey, Ulrich\|Camenisch Gross, Ulrike\|Freyholdt, Tobias\|Cathomas, Richard
PMID:	25427581

2097.
Journal:	BMC Cancer. 2014 Nov 29;14:891.
Title:	Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists.
Author:	Silva, Ana-Luisa\|Dawson, Sarah N\|Arends, Mark J\|Guttula, Kiran\|Hall, Nigel\|Cameron, Ewen A\|Huang, Tim H-M\|Brenton, James D\|Tavare, Simon\|Bienz, Mariann\|Ibrahim, Ashraf E K
PMID:	25432628

2098.
Journal:	Int Surg. 2014 Nov-Dec;99(6):795-801.
Title:	Conversion Therapy Using mFOLFOX6 With Panitumumab for Unresectable Liver Metastases From Multiple Colorectal Cancers With Familial Adenomatous Polyposis.
Author:	Toiyama, Yuji\|Inoue, Yasuhiro\|Kitajima, Takahito\|Okigami, Masato\|Kawamura, Mikio\|Kawamoto, Aya\|Okugawa, Yoshinaga\|Hiro, Jyunichiro\|Tanaka, Koji\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	25437589

2099.
Journal:	Clin Colorectal Cancer. 2014 Dec;13(4):207-12.
Title:	Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.
Author:	Cercek, Andrea\|Shia, Jinru\|Gollub, Marc\|Chou, Joanne F\|Capanu, Marinela\|Raasch, Pamela\|Reidy-Lagunes, Diane\|Proia, David A\|Vakiani, Efsevia\|Solit, David B\|Saltz, Leonard B
PMID:	25444464

2100.
Journal:	J Nucl Med. 2014 Dec;55(12):2038-44.
Title:	Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.
Author:	Iwamoto, Masayoshi\|Kawada, Kenji\|Nakamoto, Yuji\|Itatani, Yoshiro\|Inamoto, Susumu\|Toda, Kosuke\|Kimura, Hiroyuki\|Sasazuki, Takehiko\|Shirasawa, Senji\|Okuyama, Hiroaki\|Inoue, Masahiro\|Hasegawa, Suguru\|Togashi, Kaori\|Sakai, Yoshiharu
PMID:	25453050

2101.
Journal:	World J Gastroenterol. 2014 Nov 28;20(44):16398-408.
Title:	Recent applications of chemosensitivity tests for colorectal cancer treatment.
Author:	Yoon, Yong Sik\|Kim, Jin Cheon
PMID:	25469008

2102.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2014 Sep;43(9):583-7.
Title:	[Detection of KRAS gene mutations in colorectal carcinoma: a study of 6 364 patients].
Author:	Wang, Dong\|Liang, Wang\|Duan, Xiaowei\|Liu, Ling\|Shen, Hao\|Peng, Yongji\|Li, Bin
PMID:	25471497

2103.
Journal:	Hum Vaccin Immunother. 2014;10(11):3196-200.
Title:	TroVax in colorectal cancer.
Author:	Rowe, Julie\|Cen, Putao
PMID:	25483641

2104.
Journal:	MAbs. 2014;6(6):1571-84.
Title:	CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.
Author:	Oberst, Michael D\|Fuhrmann, Stacy\|Mulgrew, Kathy\|Amann, Maria\|Cheng, Lily\|Lutterbuese, Petra\|Richman, Laura\|Coats, Steve\|Baeuerle, Patrick A\|Hammond, Scott A
PMID:	25484061

2105.
Journal:	PLoS One. 2014 Dec 11;9(12):e114440.
Title:	Mini profile of potential anticancer properties of propofol.
Author:	Song, Jing\|Shen, Yenji\|Zhang, Jing\|Lian, Qingquan
PMID:	25502773

2106.
Journal:	BMC Cancer. 2014 Dec 16;14:965.
Title:	DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.
Author:	Martinez-Useros, Javier\|Rodriguez-Remirez, Maria\|Borrero-Palacios, Aurea\|Moreno, Irene\|Cebrian, Arancha\|Gomez del Pulgar, Teresa\|del Puerto-Nevado, Laura\|Vega-Bravo, Ricardo\|Puime-Otin, Alberto\|Perez, Nuria\|Zazo, Sandra\|Senin, Clara\|Fernandez-Acenero, Mar
PMID:	25515240

2107.
Journal:	Am J Cancer Res. 2014 Nov 19;4(6):824-37. eCollection 2014.
Title:	Establishment of genetically diverse patient-derived xenografts of colorectal cancer.
Author:	Burgenske, Danielle M\|Monsma, David J\|Dylewski, Dawna\|Scott, Stephanie B\|Sayfie, Aaron D\|Kim, Donald G\|Luchtefeld, Martin\|Martin, Katie R\|Stephenson, Paul\|Hostetter, Galen\|Dujovny, Nadav\|MacKeigan, Jeffrey P
PMID:	25520871

2108.
Journal:	F1000Prime Rep. 2014 Nov 4;6:108.
Title:	Management of colorectal cancer.
Author:	Stintzing, Sebastian
PMID:	25580262

2109.
Journal:	Front Surg. 2015 Jan 5;1:50.
Title:	Immunohistochemistry - microarray analysis of patients with peritoneal metastases of appendiceal or colorectal origin.
Author:	Green, Danielle E\|Jayakrishnan, Thejus T\|Hwang, Michael\|Pappas, Sam G\|Gamblin, T Clark\|Turaga, Kiran K
PMID:	25593974

2110.
Journal:	Pol J Pathol. 2014 Dec;65(4):257-66.
Title:	Molecular pathology of colorectal cancer.
Author:	Bosman, Ft\|Yan, P
PMID:	25693079

2111.
Journal:	Rev Med Chil. 2014 Nov;142(11):1407-14.
Title:	[KRAS gene somatic mutations in Chilean patients with colorectal cancer].
Author:	Hurtado, Claudia\|Encina, Gonzalo\|Wielandt, Ana Maria\|Zarate, Alejandro Jose\|Castro, Magdalena\|Carrillo, Katya\|Kronberg, Udo\|Lopez-Kostner, Francisco
PMID:	25694286

2112.
Journal:	J Med Life. 2014 Oct-Dec;7(4):581-7.
Title:	Prognostic significance of KRAS gene mutations in colorectal cancer--preliminary study.
Author:	Dinu, D\|Dobre, M\|Panaitescu, E\|Birla, R\|Iosif, C\|Hoara, P\|Caragui, A\|Boeriu, M\|Constantinoiu, S\|Ardeleanu, C
PMID:	25713627

2113.
Journal:	Hepatogastroenterology. 2014 Oct;61(135):1946-53.
Title:	Impact of KRAS mutation on outcome of patients with metastatic colorectal cancer.
Author:	Chang, Yu-Yao\|Lin, Jen-Kou\|Lin, Tzu-Chen\|Chen, Wei-Shone\|Jeng, Kai-Jiang\|Yang, Shung-Haur\|Wang, Huann-Sheng\|Lan, Yuan-Tzu\|Lin, Chun-Chi\|Liang, Wen-Yih\|Chang, Shih-Ching
PMID:	25713893

2114.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):1572-4.
Title:	[Surgical resection after chemotherapy for advanced rectal cancer - report of a case].
Author:	Suda, Kazuyoshi\|Kameyama, Hitoshi\|Shimada, Yoshifumi\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Minagawa, Masahiro\|Kosugi, Shinichi\|Koyama, Yu\|Wakai, Toshifumi
PMID:	25731256

2115.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):1701-3.
Title:	[A case of postoperative colon cancer with peritoneal dissemination in which a long-term response was achieved using panitumumab maintenance therapy].
Author:	Takahashi, Hidenori\|Ishikawa, Toshiaki\|Iwata, Noriko\|Baba, Hironobu\|Someno, Yasunori\|Okazaki, Satoshi\|Matsuyama, Takatoshi\|Ishiguro, Megumi\|Kobayashi, Hirotoshi\|Iida, Satoru\|Uetake, Hiroyuki\|Sugihara, Kenichi
PMID:	25731301

2116.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):1746-8.
Title:	[A case of stage IV rectal cancer successfully resected after chemotherapy (mFOLFOX6 plus panitumumab)].
Author:	Ando, Yasuhisa\|Kadokawa, Yoshio\|Aisu, Yuki\|Honda, Kotaro\|Nishino, Hiroto\|Nishiuchi, Aya\|Kato, Sigeru\|Machimoto, Takafumi\|Asao, Yoshito\|Furuyama, Hiroaki\|Yoshimura, Tsunehiro
PMID:	25731316

2117.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):2145-7.
Title:	[Mixed adenoneuroendocrine carcinoma with multiple liver metastases successfully treated by cetuximab/CPT-11 chemotherapy followed by curative resection - a case report].
Author:	Tani, Keigo\|Seyama, Yasuji\|Inada, Kentaro\|Matsuoka, Yujiro\|Takahashi, Masamichi\|Tanizawa, Tohru\|Warabi, Masahiro\|Nasu, Keiichi\|Wada, Ikuo\|Maeshiro, Tsuyoshi\|Miyamoto, Sachio\|Umekita, Nobutaka
PMID:	25731451

2118.
Journal:	Eksp Klin Gastroenterol. 2014;(7):4-12.
Title:	[The alternative way of colorectal cancer developing. The histogenetic and molecular features of serrated lesions (review, continued)].
Author:	Ageikina, N V\|Duvanskii, V A\|Kniazev, M V\|Mal'kov, P G\|Danilova, N V\|Kharlova, O A
PMID:	25842399

2119.
Journal:
Title:
Author:	Meleth, Sreelatha\|Reeder-Hayes, Katherine\|Ashok, Mahima\|Clark, Robert\|Funkhouser, William\|Wines, Roberta\|Hill, Christine\|Shanahan, Ellen\|McClure, Emily\|Burson, Katrina\|Coker-Schwimmer, Manny\|Garge, Nikhil\|Jonas, Daniel E
PMID:	25905152

2120.
Journal:	Free Radic Biol Med. 2014 Oct;75 Suppl 1:S13.
Title:	Akt mediated ROS-dependent selective targeting of mutant KRAS tumors.
Author:	Iskandar, Kartini\|Rezlan, Majidah\|Pervaiz, Shazib
PMID:	26461287

2121.
Journal:	Gastrointest Tumors. 2014 May;1(4):209-20.
Title:	Colorectal Cancer: Personalized Therapy.
Author:	Leichsenring, Jona\|Koppelle, Adrian\|Reinacher-Schick, Ank
PMID:	26676107

2122.
Journal:	Thorac Cancer. 2014 Sep;5(5):398-404.
Title:	Adjuvant systemic chemotherapy with or without bevacizumab in patients with resected pulmonary metastases from colorectal cancer.
Author:	Turan, Nedim\|Benekli, Mustafa\|Dane, Faysal\|Unal, Olcun Umit\|Kara, Hasan Volkan\|Koca, Dogan\|Balvan, Ozlem\|Eren, Tulay\|Tastekin, Didem\|Helvaci, Kaan\|Berk, Veli\|Demirci, Umut\|Ozturk, Selcuk Cemil\|Dogan, Erkan\|Cetin, Bulent\|Kucukoner, Mehmet\|Tonyali, Onder\|Tu
PMID:	26763794

2123.
Journal:	Indian J Cancer. 2014 Oct-Dec;51(4):531-7.
Title:	Prevalence of KRAS mutations in metastatic colorectal cancer: A retrospective observational study from India.
Author:	Veldore, V H\|Rao, M R\|Prabhudesai, S A\|Tejaswi, R\|Kakara, S\|Pattanayak, S\|Krishnamoorthy, N\|Tejaswini, B N\|Hazarika, D\|Gangoli, A\|Rahman, S M\|Dixit, J\|Naik, R\|Diwakar, R B\|Satheesh, C T\|Shashidhara, H P\|Patil, S\|Gopinath, K S\|Kumar, B S
PMID:	26842186

2124.
Journal:	Microarrays (Basel). 2014 Jun 26;3(3):168-79.
Title:	Molecular Diagnostic Applications in Colorectal Cancer.
Author:	Huth, Laura\|Jakel, Jorg\|Dahl, Edgar
PMID:	27600342

2125.
Journal:	Curr Clin Pharmacol. 2015;10(1):73-81.
Title:	K-Ras, intestinal homeostasis and colon cancer.
Author:	Goel, Sanjay\|Huang, Jie\|Klampfer, Lidija
PMID:	24219000

2126.
Journal:	J Magn Reson Imaging. 2015 Feb;41(2):474-80.
Title:	Correlation of dynamic contrast-enhanced MRI perfusion parameters with angiogenesis and biologic aggressiveness of rectal cancer: Preliminary results.
Author:	Yeo, Dong-Myung\|Oh, Soon Nam\|Jung, Chan-Kwon\|Lee, Myung Ah\|Oh, Seong Taek\|Rha, Sung Eun\|Jung, Seung Eun\|Byun, Jae Young\|Gall, Peter\|Son, Yohan
PMID:	24375840

2127.
Journal:	Oncogene. 2015 Jan 22;34(4):531-6.
Title:	A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
Author:	Bajpe, P K\|Prahallad, A\|Horlings, H\|Nagtegaal, I\|Beijersbergen, R\|Bernards, R
PMID:	24469059

2128.
Journal:	Int J Cancer. 2015 Jul 15;137(2):262-6.
Title:	Personalised cancer medicine.
Author:	Jackson, Sarah E\|Chester, John D
PMID:	24789362

2129.
Journal:	Leukemia. 2015 Jan;29(1):27-37.
Title:	Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Author:	Weisberg, Ellen\|Nonami, Atsushi\|Chen, Zhao\|Liu, Feiyang\|Zhang, Jianming\|Sattler, Martin\|Nelson, Erik\|Cowens, Kristen\|Christie, Amanda L\|Mitsiades, Constantine\|Wong, Kwok-Kin\|Liu, Qingsong\|Gray, Nathanael\|Griffin, James D
PMID:	24791855

2130.
Journal:	Int J Cancer. 2015 Jan 1;136(1):83-90.
Title:	Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.
Author:	Schirripa, Marta\|Cremolini, Chiara\|Loupakis, Fotios\|Morvillo, Manfredi\|Bergamo, Francesca\|Zoratto, Federica\|Salvatore, Lisa\|Antoniotti, Carlotta\|Marmorino, Federica\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|De Gregorio, Veronica\|Giannini, Riccardo
PMID:	24806288

2131.
Journal:	Gut. 2015 Apr;64(4):627-35.
Title:	Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics.
Author:	Shigeyasu, Kunitoshi\|Tazawa, Hiroshi\|Hashimoto, Yuuri\|Mori, Yoshiko\|Nishizaki, Masahiko\|Kishimoto, Hiroyuki\|Nagasaka, Takeshi\|Kuroda, Shinji\|Urata, Yasuo\|Goel, Ajay\|Kagawa, Shunsuke\|Fujiwara, Toshiyoshi
PMID:	24870621

2132.
Journal:	Ann Surg Oncol. 2015 Jan;22(1):187-94.
Title:	KRAS mutation is associated with worse prognosis in stage III or high-risk stage II colon cancer patients treated with adjuvant FOLFOX.
Author:	Lee, Dae-Won\|Kim, Kyung Ju\|Han, Sae-Won\|Lee, Hyun Jung\|Rhee, Ye Young\|Bae, Jeong Mo\|Cho, Nam-Yun\|Lee, Kyung-Hun\|Kim, Tae-Yong\|Oh, Do-Youn\|Im, Seock-Ah\|Bang, Yung-Jue\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	24889488

2133.
Journal:	Mod Pathol. 2015 Jan;28(1):146-58.
Title:	Distinct WNT/beta-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum.
Author:	Murakami, Takashi\|Mitomi, Hiroyuki\|Saito, Tsuyoshi\|Takahashi, Michiko\|Sakamoto, Naoto\|Fukui, Naoshi\|Yao, Takashi\|Watanabe, Sumio
PMID:	24925057

2134.
Journal:	Gut. 2015 Apr;64(4):636-45.
Title:	Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.
Author:	Yu, Jun\|Wu, William K K\|Li, Xiangchun\|He, Jun\|Li, Xiao-Xing\|Ng, Simon S M\|Yu, Chang\|Gao, Zhibo\|Yang, Jie\|Li, Miao\|Wang, Qiaoxiu\|Liang, Qiaoyi\|Pan, Yi\|Tong, Joanna H\|To, Ka F\|Wong, Nathalie\|Zhang, Ning\|Chen, Jie\|Lu, Youyong\|Lai, Paul B S\|Chan, Francis K L\|
PMID:	24951259

2135.
Journal:	Mod Pathol. 2015 Feb;28(2):268-78.
Title:	Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma.
Author:	Tsai, Jia-Huei\|Lin, Yu-Lin\|Cheng, Yi-Chen\|Chen, Chien-Chuan\|Lin, Liang-In\|Tseng, Li-Hui\|Cheng, Mei-Ling\|Liau, Jau-Yu\|Jeng, Yung-Ming
PMID:	25081749

2136.
Journal:	Biosens Bioelectron. 2015 Jan 15;63:472-477.
Title:	Engineering plasmonic nanorod arrays for colon cancer marker detection.
Author:	Dodson, Stephanie L\|Cao, Cuong\|Zaribafzadeh, Hamed\|Li, Shuzhou\|Xiong, Qihua
PMID:	25129509

2137.
Journal:	Mol Carcinog. 2015 Nov;54(11):1264-74.
Title:	Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of beta-catenin/Ctnnb1 as the driver gene for the carcinogenesis.
Author:	Wang, Hong\|Zhou, Hong\|Liu, Anna\|Guo, Xiangyi\|Yang, Chung S
PMID:	25131582

2138.
Journal:	Mod Pathol. 2015 Mar;28(3):414-27.
Title:	A clinicopathological and molecular analysis of 200 traditional serrated adenomas.
Author:	Bettington, Mark L\|Walker, Neal I\|Rosty, Christophe\|Brown, Ian S\|Clouston, Andrew D\|McKeone, Diane M\|Pearson, Sally-Ann\|Klein, Kerenaftali\|Leggett, Barbara A\|Whitehall, Vicki L J
PMID:	25216220

2139.
Journal:	Invest New Drugs. 2015 Feb;33(1):269-70.
Title:	Erratum to: Effect of simvastatin plus cetuximab/irinotecan for KRAS mutant colorectal cancer and predictive value of the RAS signature for treatment response to cetuximab.
Author:	Lee, Jeeyun\|Hong, Yong Sang\|Hong, Jung Yong\|Han, Se Won\|Kim, Tae Won\|Kang, Hye Jin\|Kim, Tae You\|Kim, Kyu-Pyo\|Kim, Suk Hyung\|Do, In-Gu\|Kim, Kyoung-Mee\|Sohn, Insuk\|Park, Se Hoon\|Park, Joon Oh\|Lim, Ho Yeong\|Cho, Yong Beom\|Lee, Woo Yong\|Yun, Seong Hyeon\|Kim,
PMID:	25236593

2140.
Journal:	Clin Cancer Res. 2015 Mar 1;21(5):1087-97.
Title:	Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy.
Author:	Laurent-Puig, Pierre\|Pekin, Deniz\|Normand, Corinne\|Kotsopoulos, Steve K\|Nizard, Philippe\|Perez-Toralla, Karla\|Rowell, Rachel\|Olson, Jeff\|Srinivasan, Preethi\|Le Corre, Delphine\|Hor, Thevy\|El Harrak, Zakaria\|Li, Xinyu\|Link, Darren R\|Bouche, Olivier\|Emile, J
PMID:	25248381

2141.
Journal:	Pathol Oncol Res. 2015 Apr;21(2):399-404.
Title:	Changes of KRAS Exon 2 Codon 12/13 Mutation Status in Recurrent Colorectal Cancer.
Author:	Docs, Otto\|Fazakas, Ferenc\|Horvath, Nora Lugosine\|Toth, Laszlo\|Andras, Csilla\|Horvath, Zsolt\|Mehes, Gabor
PMID:	25248721

2142.
Journal:	Cancer. 2015 Jan 1;121(1):34-42.
Title:	Identification of novel mutations by exome sequencing in African American colorectal cancer patients.
Author:	Ashktorab, Hassan\|Daremipouran, Mohammad\|Devaney, Joe\|Varma, Sudhir\|Rahi, Hamed\|Lee, Edward\|Shokrani, Babak\|Schwartz, Russell\|Nickerson, Michael L\|Brim, Hassan
PMID:	25250560

2143.
Journal:	Mol Carcinog. 2015 Nov;54(11):1442-50.
Title:	MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Author:	Ress, Anna Lena\|Stiegelbauer, Verena\|Winter, Elke\|Schwarzenbacher, Daniela\|Kiesslich, Tobias\|Lax, Sigurd\|Jahn, Stefan\|Deutsch, Alexander\|Bauernhofer, Thomas\|Ling, Hui\|Samonigg, Hellmut\|Gerger, Armin\|Hoefler, Gerald\|Pichler, Martin
PMID:	25256312

2144.
Journal:	Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):186-96.
Title:	Human cytomegalovirus and Epstein-Barr virus infection impact on (18)F-FDG PET/CT SUVmax, CT volumetric and KRAS-based parameters of patients with locally advanced rectal cancer treated with neoadjuvant therapy.
Author:	Sole, Claudio V\|Calvo, Felipe A\|Ferrer, Carlos\|Alvarez, Emilio\|Carreras, Jose L\|Ochoa, Enrique
PMID:	25269837

2145.
Journal:	Gastroenterology. 2015 Jan;148(1):77-87.e2.
Title:	Association between molecular subtypes of colorectal cancer and patient survival.
Author:	Phipps, Amanda I\|Limburg, Paul J\|Baron, John A\|Burnett-Hartman, Andrea N\|Weisenberger, Daniel J\|Laird, Peter W\|Sinicrope, Frank A\|Rosty, Christophe\|Buchanan, Daniel D\|Potter, John D\|Newcomb, Polly A
PMID:	25280443

2146.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):613-27.
Title:	Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway.
Author:	Xu, Wei\|Wang, Ziwei\|Zhang, Wei\|Qian, Kun\|Li, Hui\|Kong, Dequan\|Li, Yuqiang\|Tang, Yucheng
PMID:	25305448

2147.
Journal:	Gastroenterology. 2015 Jan;148(1):88-99.
Title:	Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes.
Author:	Sinicrope, Frank A\|Shi, Qian\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Dienstmann, Rodrigo\|Guinney, Justin\|Bot, Brian M\|Tejpar, Sabine\|Delorenzi, Mauro\|Goldberg, Richard M\|Mahoney, Michelle\|Sargent, Daniel J\|Alberts, Steven R
PMID:	25305506

2148.
Journal:	Anal Bioanal Chem. 2015 Mar;407(8):2107-16.
Title:	Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.
Author:	Buck, Achim\|Halbritter, Susanne\|Spath, Christoph\|Feuchtinger, Annette\|Aichler, Michaela\|Zitzelsberger, Horst\|Janssen, Klaus-Peter\|Walch, Axel
PMID:	25311193

2149.
Journal:	J Clin Pathol. 2015 Jan;68(1):83-5.
Title:	KRAS mutation status impacts diagnosis and treatment decision in a patient with two colon tumours: a case report.
Author:	Li, Xiaodong\|Pezeshkpour, G\|Phan, Ryan T
PMID:	25313410

2150.
Journal:	Ann Oncol. 2015 Jan;26(1):132-40.
Title:	Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial.
Author:	Elez, E\|Kocakova, I\|Hohler, T\|Martens, U M\|Bokemeyer, C\|Van Cutsem, E\|Melichar, B\|Smakal, M\|Csoszi, T\|Topuzov, E\|Orlova, R\|Tjulandin, S\|Rivera, F\|Straub, J\|Bruns, R\|Quaratino, S\|Tabernero, J
PMID:	25319061

2151.
Journal:	Ann Surg Oncol. 2015 Apr;22(4):1226-1235.
Title:	Prognostic significance and molecular features of signet-ring cell and mucinous components in colorectal carcinoma.
Author:	Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Li, Tingting\|Yasunari, Mika\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Harris, Curtis C\|Qian, Zhi Rong\|Ogino, Shuji
PMID:	25326395

2152.
Journal:	Tumour Biol. 2015 Feb;36(2):1091-7.
Title:	Combine MEK inhibition with PI3K/mTOR inhibition exert inhibitory tumor growth effect on KRAS and PIK3CA mutation CRC xenografts due to reduced expression of VEGF and matrix metallopeptidase-9.
Author:	E, Jifu\|Xing, Junjie\|Gong, Haifeng\|He, Jian\|Zhang, Wei
PMID:	25326806

2153.
Journal:	Virchows Arch. 2015 Jan;466(1):13-20.
Title:	Medullary carcinoma of the colon: can the undifferentiated be differentiated?
Author:	Fiehn, Anne-Marie Kanstrup\|Grauslund, Morten\|Glenthoj, Anders\|Melchior, Linea Cecilie\|Vainer, Ben\|Willemoe, Gro Linno
PMID:	25339302

2154.
Journal:	FASEB J. 2015 Feb;29(2):464-76.
Title:	Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
Author:	Alamo, Patricia\|Gallardo, Alberto\|Di Nicolantonio, Federica\|Pavon, Miguel Angel\|Casanova, Isolda\|Trias, Manuel\|Mangues, Maria Antonia\|Lopez-Pousa, Antonio\|Villaverde, Antonio\|Vazquez, Esther\|Bardelli, Alberto\|Cespedes, Maria Virtudes\|Mangues, Ramon
PMID:	25359494

2155.
Journal:	Ann Oncol. 2015 Jan;26(1):126-32.
Title:	Prognosis of stage II and III colon cancer treated with adjuvant 5-fluorouracil or FOLFIRI in relation to microsatellite status: results of the PETACC-3 trial.
Author:	Klingbiel, D\|Saridaki, Z\|Roth, A D\|Bosman, F T\|Delorenzi, M\|Tejpar, S
PMID:	25361982

2156.
Journal:	J Appl Genet. 2015 May;56(2):185-92.
Title:	Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.
Author:	Szmida, Elzbieta\|Karpinski, Pawel\|Leszczynski, Przemyslaw\|Sedziak, Tomasz\|Kielan, Wojciech\|Ostasiewicz, Pawel\|Sasiadek, Maria M
PMID:	25366420

2157.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):264-73.
Title:	Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.
Author:	Garcia-Alfonso, P\|Garcia-Foncillas, J\|Salazar, R\|Perez-Segura, P\|Garcia-Carbonero, R\|Musulen-Palet, E\|Cuatrecasas, M\|Landolfi, S\|Ramon Y Cajal, S\|Navarro, S
PMID:	25373533

2158.
Journal:	J Clin Pathol. 2015 Jan;68(1):64-8.
Title:	Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients.
Author:	Malapelle, Umberto\|Vigliar, Elena\|Sgariglia, Roberta\|Bellevicine, Claudio\|Colarossi, Lorenzo\|Vitale, Domenico\|Pallante, Pierlorenzo\|Troncone, Giancarlo
PMID:	25378536

2159.
Journal:	Eur J Health Econ. 2015 Dec;16(9):985-94.
Title:	Some economics on personalized and predictive medicine.
Author:	Antonanzas, F\|Juarez-Castello, C A\|Rodriguez-Ibeas, R
PMID:	25381039

2160.
Journal:	J Gastroenterol. 2015 Jun;50(6):657-66.
Title:	Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X.
Author:	Sanchez-Tome, E\|Rivera, B\|Perea, J\|Pita, G\|Rueda, D\|Mercadillo, F\|Canal, A\|Gonzalez-Neira, A\|Benitez, J\|Urioste, M
PMID:	25381643

2161.
Journal:	Histopathology. 2015 Apr;66(5):715-25.
Title:	Tyrosine kinase receptor B (TrkB) expression in colorectal cancers highlights anoikis resistance as a survival mechanism of tumour budding cells.
Author:	Dawson, Heather\|Grundmann, Sandra\|Koelzer, Viktor H\|Galvan, Jose A\|Kirsch, Richard\|Karamitopoulou, Eva\|Lugli, Alessandro\|Inderbitzin, Daniel\|Zlobec, Inti
PMID:	25382057

2162.
Journal:	Clin Cancer Res. 2015 Jan 15;21(2):357-64.
Title:	Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patients.
Author:	Lee, Keun-Wook\|Lee, Sung Sook\|Kim, Sang-Bae\|Sohn, Bo Hwa\|Lee, Hyun-Sung\|Jang, Hee-Jin\|Park, Yun-Yong\|Kopetz, Scott\|Kim, Sung Soo\|Oh, Sang Cheul\|Lee, Ju-Seog
PMID:	25388162

2163.
Journal:	Clin Cancer Res. 2015 Jan 15;21(2):347-56.
Title:	Deregulation of the PP2A inhibitor SET shows promising therapeutic implications and determines poor clinical outcome in patients with metastatic colorectal cancer.
Author:	Cristobal, Ion\|Rincon, Raul\|Manso, Rebeca\|Carames, Cristina\|Zazo, Sandra\|Madoz-Gurpide, Juan\|Rojo, Federico\|Garcia-Foncillas, Jesus
PMID:	25388166

2164.
Journal:	Mol Pharm. 2015 Jan 5;12(1):10-7.
Title:	Serial in vivo imaging using a fluorescence probe allows identification of tumor early response to cetuximab immunotherapy.
Author:	Ma, Teng\|Liu, Hao\|Sun, Xianlei\|Gao, Liquan\|Shi, Jiyun\|Zhao, Huiyun\|Jia, Bing\|Wang, Fan\|Liu, Zhaofei
PMID:	25397907

2165.
Journal:	Int J Cancer. 2015 Jun 15;136(12):2811-21.
Title:	MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer.
Author:	Renaud, Florence\|Vincent, Audrey\|Mariette, Christophe\|Crepin, Michel\|Stechly, Laurence\|Truant, Stephanie\|Copin, Marie-Christine\|Porchet, Nicole\|Leteurtre, Emmanuelle\|Van Seuningen, Isabelle\|Buisine, Marie-Pierre
PMID:	25403854

2166.
Journal:	Oncologist. 2015 Jan;20(1):14-8.
Title:	Cost estimates and economic implications of expanded RAS testing in metastatic colorectal cancer.
Author:	Kircher, Sheetal M\|Mohindra, Nisha\|Nimeiri, Halla
PMID:	25410095

2167.
Journal:	Br J Cancer. 2015 Jan 20;112(2):313-8.
Title:	Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.
Author:	Augustine, T A\|Baig, M\|Sood, A\|Budagov, T\|Atzmon, G\|Mariadason, J M\|Aparo, S\|Maitra, R\|Goel, S
PMID:	25412235

2168.
Journal:	Mol Carcinog. 2015 Dec;54(12):1786-95.
Title:	Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics.
Author:	Laskar, Ruhina Shirin\|Ghosh, Sankar Kumar\|Talukdar, Fazlur Rahman
PMID:	25418895

2169.
Journal:	Target Oncol. 2015 Sep;10(3):415-21.
Title:	Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?
Author:	Allard, M A\|Saffroy, R\|de la Maisonneuve, P Bouvet\|Ricca, L\|Bosselut, N\|Hamelin, J\|Lecorche, E\|Bejarano, M A\|Innominato, P\|Sebagh, M\|Adam, R\|Morere, J F\|Lemoine, A
PMID:	25420993

2170.
Journal:	Oncol Lett. 2015 Jan;9(1):454-458.
Title:	Long-fragment DNA as a potential marker for stool-based detection of colorectal cancer.
Author:	Zhang, Yibo\|Suehiro, Yutaka\|Shindo, Yoshitaro\|Sakai, Kouhei\|Hazama, Shoichi\|Higaki, Shingo\|Sakaida, Isao\|Oka, Masaaki\|Yamasaki, Takahiro
PMID:	25436008

2171.
Journal:	Clin Chim Acta. 2015 Jan 15;439:97-101.
Title:	Improved sensitivity of circulating tumor DNA measurement using short PCR amplicons.
Author:	Andersen, Rikke Fredslund\|Spindler, Karen-Lise Garm\|Brandslund, Ivan\|Jakobsen, Anders\|Pallisgaard, Niels
PMID:	25446878

2172.
Journal:	Biochim Biophys Acta. 2015 Jan;1855(1):104-21.
Title:	Portrait of the PI3K/AKT pathway in colorectal cancer.
Author:	Danielsen, Stine Aske\|Eide, Peter Wold\|Nesbakken, Arild\|Guren, Tormod\|Leithe, Edward\|Lothe, Ragnhild A
PMID:	25450577

2173.
Journal:	Gene. 2015 Feb 10;556(2):227-34.
Title:	Genome-wide analysis of long noncoding RNA signature in human colorectal cancer.
Author:	Xue, Yao\|Ma, Gaoxiang\|Gu, Dongying\|Zhu, Lingjun\|Hua, Qiuhan\|Du, Mulong\|Chu, Haiyan\|Tong, Na\|Chen, Jinfei\|Zhang, Zhengdong\|Wang, Meilin
PMID:	25456707

2174.
Journal:	Mol Clin Oncol. 2015 Jan;3(1):179-184.
Title:	Association between specific KRAS mutations and the clinicopathological characteristics of colorectal tumors.
Author:	Kodaz, Hilmi\|Hacibekiroglu, Ilhan\|Erdogan, Bulent\|Turkmen, Esma\|Tozkir, Hilmi\|Albayrak, Dogan\|Uzunoglu, Sernaz\|Cicin, Irfan
PMID:	25469291

2175.
Journal:	Ann Surg Oncol. 2015 Aug;22(8):2640-8.
Title:	Association of MicroRNA-31-5p with Clinical Efficacy of Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.
Author:	Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Mitsuhashi, Kei\|Ito, Miki\|Okuda, Hiroyuki\|Kanno, Shinichi\|Naito, Takafumi\|Yoshii, Shinji\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Adachi, Yasushi\|Okita, Kenji\|Hirata, Koichi\|Imamura, Yu\|B
PMID:	25472647

2176.
Journal:	Expert Rev Mol Diagn. 2015 Mar;15(3):375-84.
Title:	KRAS mutation testing in clinical practice.
Author:	Perincheri, Sudhir\|Hui, Pei
PMID:	25487540

2177.
Journal:	Cancer. 2015 Apr 15;121(8):1195-203.
Title:	RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer.
Author:	Yaeger, Rona\|Cowell, Elizabeth\|Chou, Joanne F\|Gewirtz, Alexandra N\|Borsu, Laetitia\|Vakiani, Efsevia\|Solit, David B\|Rosen, Neal\|Capanu, Marinela\|Ladanyi, Marc\|Kemeny, Nancy
PMID:	25491172

2178.
Journal:	Int J Surg. 2015 Jan;13:272-9.
Title:	MicroRNAs associated with initiation and progression of colonic polyp: a feasibility study.
Author:	Aslam, Muhammad Imran\|Hussein, Samir\|West, Kevin\|Singh, Baljit\|Jameson, John Stuart\|Pringle, James Howard
PMID:	25496852

2179.
Journal:	Oncogene. 2015 Sep 17;34(38):4914-27.
Title:	Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author:	Lemieux, E\|Cagnol, S\|Beaudry, K\|Carrier, J\|Rivard, N
PMID:	25500543

2180.
Journal:	Anticancer Drugs. 2015 Apr;26(4):371-8.
Title:	Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
Author:	Gamba, Sebastian\|Camaj, Peter\|Heinemann, Volker\|Laubender, Rudiger P\|Wang, Yan\|Zhao, Yue\|Stintzing, Sebastian\|Giessen, Clemens\|Boeck, Stefan\|Haertl, Christoph\|Bruns, Christiane J\|Modest, Dominik P
PMID:	25514114

2181.
Journal:	Tumour Biol. 2015 May;36(5):3301-8.
Title:	LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo.
Author:	Zhou, Jundong\|Zheng, Bing\|Ji, Jiansong\|Shen, Fei\|Min, Han\|Liu, Biao\|Wu, Jinchang\|Zhang, Shuyu
PMID:	25524577

2182.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):620-30.
Title:	IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
Author:	Huang, Fei\|Chang, Han\|Greer, Ann\|Hillerman, Stephen\|Reeves, Karen A\|Hurlburt, Warren\|Cogswell, John\|Patel, Dharmesh\|Qi, Zhenhao\|Fairchild, Craig\|Ryseck, Rolf-Peter\|Wong, Tai W\|Finckenstein, Friedrich G\|Jackson, Jeffrey\|Carboni, Joan M
PMID:	25527633

2183.
Journal:	Dig Dis. 2015;33(1):28-37.
Title:	Serrated and non-serrated precursor lesions of colorectal cancer.
Author:	Langner, Cord
PMID:	25531494

2184.
Journal:	Pharmacogenomics J. 2015 Aug;15(4):354-62.
Title:	Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Author:	Maus, M K H\|Hanna, D L\|Stephens, C L\|Astrow, S H\|Yang, D\|Grimminger, P P\|Loupakis, F\|Hsiang, J H\|Zeger, G\|Wakatsuki, T\|Barzi, A\|Lenz, H-J
PMID:	25532759

2185.
Journal:	J Mol Diagn. 2015 Mar;17(2):193-200.
Title:	Target-enriched next-generation sequencing reveals differences between primary and secondary ovarian tumors in formalin-fixed, paraffin-embedded tissue.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Fleuren, Gert Jan\|Minderhout, Ivonne\|Snowdowne, Ronelle\|Tops, Carli\|van Wezel, Tom\|Morreau, Hans
PMID:	25545608

2186.
Journal:	Mol Cancer Res. 2015 Apr;13(4):659-69.
Title:	Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.
Author:	Okamoto, Koichi\|Zaanan, Aziz\|Kawakami, Hisato\|Huang, Shengbing\|Sinicrope, Frank A
PMID:	25548100

2187.
Journal:	J Cancer. 2015 Jan 1;6(1):70-81.
Title:	ERCC1 Induction after Oxaliplatin Exposure May Depend on KRAS Mutational Status in Colorectal Cancer Cell Line: In Vitro Veritas.
Author:	Orlandi, A\|Di Salvatore, M\|Bagala, C\|Basso, M\|Strippoli, A\|Plastino, F\|Calegari, M A\|Cassano, A\|Astone, A\|Barone, C
PMID:	25553091

2188.
Journal:	Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):779-84.
Title:	K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif.
Author:	Tsai, Frederick D\|Lopes, Mathew S\|Zhou, Mo\|Court, Helen\|Ponce, Odis\|Fiordalisi, James J\|Gierut, Jessica J\|Cox, Adrienne D\|Haigis, Kevin M\|Philips, Mark R
PMID:	25561545

2189.
Journal:	PLoS One. 2015 Jan 8;10(1):e0115672.
Title:	KRAS mutation analysis by PCR: a comparison of two methods.
Author:	Bolton, Louise\|Reiman, Anne\|Lucas, Katie\|Timms, Judith\|Cree, Ian A
PMID:	25568935

2190.
Journal:	Med Oncol. 2015 Feb;32(2):456.
Title:	Prognostic factors for survival with bevacizumab-based therapy in colorectal cancer patients: a systematic review and pooled analysis of 11,585 patients.
Author:	Petrelli, Fausto\|Coinu, Andrea\|Cabiddu, Mary\|Borgonovo, Karen\|Lonati, Veronica\|Ghilardi, Mara\|Barni, Sandro
PMID:	25572811

2191.
Journal:	Pathol Oncol Res. 2015 Jul;21(3):759-64.
Title:	CD44-SLC1A2 fusion transcripts in primary colorectal cancer.
Author:	Shinmura, Kazuya\|Kato, Hisami\|Igarashi, Hisaki\|Inoue, Yusuke\|Nakamura, Satoki\|Du, Chunping\|Kurachi, Kiyotaka\|Nakamura, Toshio\|Ogawa, Hiroshi\|Tanahashi, Masayuki\|Niwa, Hiroshi\|Sugimura, Haruhiko
PMID:	25576211

2192.
Journal:	Clin Cancer Res. 2015 Mar 15;21(6):1383-94.
Title:	Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer.
Author:	Baumer, Sebastian\|Baumer, Nicole\|Appel, Neele\|Terheyden, Lisa\|Fremerey, Julia\|Schelhaas, Sonja\|Wardelmann, Eva\|Buchholz, Frank\|Berdel, Wolfgang E\|Muller-Tidow, Carsten
PMID:	25589625

2193.
Journal:	Int J Med Sci. 2015 Jan 1;12(2):92-9.
Title:	Syndecan-1 expression is associated with tumor size and EGFR expression in colorectal carcinoma: a clinicopathological study of 230 cases.
Author:	Kim, Su Young\|Choi, Eun Ji\|Yun, Jeong A\|Jung, Eun Sun\|Oh, Seung Taek\|Kim, Jun Gi\|Kang, Won Kyung\|Lee, Sung Hak
PMID:	25589885

2194.
Journal:	Cancer Res. 2015 Jan 15;75(2):245-9.
Title:	Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes.
Author:	Linnekamp, Janneke F\|Wang, Xin\|Medema, Jan Paul\|Vermeulen, Louis
PMID:	25593032

2195.
Journal:	J Proteome Res. 2015 Mar 6;14(3):1535-46.
Title:	Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations.
Author:	Hammond, Dean E\|Mageean, Craig J\|Rusilowicz, Emma V\|Wickenden, Julie A\|Clague, Michael J\|Prior, Ian A
PMID:	25599653

2196.
Journal:	Mol Oncol. 2015 Apr;9(4):850-60.
Title:	Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.
Author:	Mohamed Suhaimi, Nur-Afidah\|Foong, Yu Miin\|Lee, Daniel Yoke San\|Phyo, Wai Min\|Cima, Igor\|Lee, Esther Xing Wei\|Goh, Wei Lin\|Lim, Wei-Yen\|Chia, Kee Seng\|Kong, Say Li\|Gong, Min\|Lim, Bing\|Hillmer, Axel M\|Koh, Poh Koon\|Ying, Jackie Y\|Tan, Min-Han
PMID:	25605225

2197.
Journal:	J Clin Oncol. 2015 Mar 1;33(7):692-700.
Title:	Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer.
Author:	Van Cutsem, Eric\|Lenz, Heinz-Josef\|Kohne, Claus-Henning\|Heinemann, Volker\|Tejpar, Sabine\|Melezinek, Ivan\|Beier, Frank\|Stroh, Christopher\|Rougier, Philippe\|van Krieken, J Han\|Ciardiello, Fortunato
PMID:	25605843

2198.
Journal:	Tumour Biol. 2015 Jun;36(6):4301-8.
Title:	TIMP-1 and CEA as biomarkers in third-line treatment with irinotecan and cetuximab for metastatic colorectal cancer.
Author:	Spindler, Karen-Lise Garm\|Christensen, Ib Jarle\|Nielsen, Hans Jorgen\|Jakobsen, Anders\|Brunner, Nils
PMID:	25608838

2199.
Journal:	J Clin Pathol. 2015 Apr;68(4):265-9.
Title:	KRAS mutant allele-specific imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer.
Author:	Malapelle, Umberto\|Sgariglia, Roberta\|De Stefano, Alfonso\|Bellevicine, Claudio\|Vigliar, Elena\|de Biase, Dario\|Sepe, Romina\|Pallante, Pierlorenzo\|Carlomagno, Chiara\|Tallini, Giovanni\|Troncone, Giancarlo
PMID:	25609577

2200.
Journal:	Arch Pathol Lab Med. 2015 Feb;139(2):211-8.
Title:	Challenges posed to pathologists in the detection of KRAS mutations in colorectal cancers.
Author:	Dudley, Jonathan\|Tseng, Li-Hui\|Rooper, Lisa\|Harris, Marco\|Haley, Lisa\|Chen, Guoli\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	25611103

2201.
Journal:	Clin Cancer Res. 2015 May 1;21(9):2157-66.
Title:	Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer.
Author:	Arena, Sabrina\|Bellosillo, Beatriz\|Siravegna, Giulia\|Martinez, Alejandro\|Canadas, Israel\|Lazzari, Luca\|Ferruz, Noelia\|Russo, Mariangela\|Misale, Sandra\|Gonzalez, Iria\|Iglesias, Mar\|Gavilan, Elena\|Corti, Giorgio\|Hobor, Sebastijan\|Crisafulli, Giovanni\|Salido
PMID:	25623215

2202.
Journal:	Biochem Biophys Res Commun. 2015 Feb 27;458(1):52-6.
Title:	Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis.
Author:	Kogita, Akihiro\|Yoshioka, Yasumasa\|Sakai, Kazuko\|Togashi, Yosuke\|Sogabe, Shunsuke\|Nakai, Takuya\|Okuno, Kiyotaka\|Nishio, Kazuto
PMID:	25623536

2203.
Journal:	Ann Oncol. 2015 Apr;26(4):731-6.
Title:	Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment.
Author:	Morelli, M P\|Overman, M J\|Dasari, A\|Kazmi, S M A\|Mazard, T\|Vilar, E\|Morris, V K\|Lee, M S\|Herron, D\|Eng, C\|Morris, J\|Kee, B K\|Janku, F\|Deaton, F L\|Garrett, C\|Maru, D\|Diehl, F\|Angenendt, P\|Kopetz, S
PMID:	25628445

2204.
Journal:	Am J Cancer Res. 2014 Dec 15;5(1):72-86. eCollection 2015.
Title:	Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer.
Author:	Lee, Choong-Kun\|Lee, Myung Eun\|Lee, Won Suk\|Kim, Jeong Min\|Park, Kyu Hyun\|Kim, Tae Soo\|Lee, Kang Young\|Ahn, Joong Bae\|Chung, Hyun Cheol\|Rha, Sun Young
PMID:	25628921

2205.
Journal:	World J Gastroenterol. 2015 Jan 28;21(4):1275-83.
Title:	Prognostic value of KRAS and BRAF mutations in curatively resected colorectal cancer.
Author:	Kadowaki, Shigenori\|Kakuta, Miho\|Takahashi, Shuhei\|Takahashi, Akemi\|Arai, Yoshiko\|Nishimura, Yoji\|Yatsuoka, Toshimasa\|Ooki, Akira\|Yamaguchi, Kensei\|Matsuo, Keitaro\|Muro, Kei\|Akagi, Kiwamu
PMID:	25632202

2206.
Journal:	Digestion. 2015;91(1):57-63.
Title:	Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Ito, Miki\|Mitsuhashi, Kei\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Yoshii, Shinji\|Mikami, Masashi\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hosokawa, Masao\|Sukawa, Yasutaka\|Adachi, Yasushi\|Hasegawa, Tadashi\|Okita, Kenji\|Hirata, Koi
PMID:	25632919

2207.
Journal:	BMC Cancer. 2015 Jan 31;15:26.
Title:	Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium.
Author:	Tops, Bastiaan B J\|Normanno, Nicola\|Kurth, Henriette\|Amato, Eliana\|Mafficini, Andrea\|Rieber, Nora\|Le Corre, Delphine\|Rachiglio, Anna Maria\|Reiman, Anne\|Sheils, Orla\|Noppen, Christoph\|Lacroix, Ludovic\|Cree, Ian A\|Scarpa, Aldo\|Ligtenberg, Marjolijn J L\|Laur
PMID:	25637035

2208.
Journal:	Invest New Drugs. 2015 Jun;33(3):720-8.
Title:	Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer.
Author:	Do, Khanh\|Speranza, Giovanna\|Bishop, Rachel\|Khin, Sonny\|Rubinstein, Larry\|Kinders, Robert J\|Datiles, Manuel\|Eugeni, Michelle\|Lam, Michael H\|Doyle, L Austin\|Doroshow, James H\|Kummar, Shivaani
PMID:	25637165

2209.
Journal:	Oncotarget. 2015 Feb 20;6(5):3420-31.
Title:	Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.
Author:	Alonso, Sergio\|Dai, Yuichi\|Yamashita, Kentaro\|Horiuchi, Shina\|Dai, Tomoko\|Matsunaga, Akihiro\|Sanchez-Munoz, Rosa\|Bilbao-Sieyro, Cristina\|Diaz-Chico, Juan Carlos\|Chernov, Andrei V\|Strongin, Alex Y\|Perucho, Manuel
PMID:	25638164

2210.
Journal:	Sci Rep. 2015 Feb 2;5:8065.
Title:	Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases.
Author:	Mao, Chen\|Wu, Xin-Yin\|Yang, Zu-Yao\|Threapleton, Diane Erin\|Yuan, Jin-Qiu\|Yu, Yuan-Yuan\|Tang, Jin-Ling
PMID:	25639985

2211.
Journal:	Tumour Biol. 2015 Jun;36(6):4661-70.
Title:	Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population.
Author:	Laskar, Ruhina S\|Talukdar, Fazlur R\|Choudhury, Javed H\|Singh, Seram Anil\|Kundu, Sharbadeb\|Dhar, Bishal\|Mondal, Rosy\|Ghosh, Sankar Kumar
PMID:	25647260

2212.
Journal:	Electrophoresis. 2015 Mar;36(6):937-40.
Title:	Whole genome amplification induced bias in the detection of KRAS-mutated cell populations during colorectal carcinoma tissue testing.
Author:	Stranska, Jana\|Jancik, Sylwia\|Slavkovsky, Rastislav\|Holinkova, Veronika\|Rabcanova, Miroslava\|Vojta, Petr\|Hajduch, Marian\|Drabek, Jiri
PMID:	25655305

2213.
Journal:	Oncologist. 2015 Mar;20(3):257-62.
Title:	External quality assessment unravels interlaboratory differences in quality of RAS testing for anti-EGFR therapy in colorectal cancer.
Author:	Tack, Veronique\|Ligtenberg, Marjolijn J L\|Tembuyser, Lien\|Normanno, Nicola\|Vander Borght, Sara\|Han van Krieken, J\|Dequeker, Elisabeth M C
PMID:	25657200

2214.
Journal:	Curr Gastroenterol Rep. 2015 Feb;17(2):431.
Title:	Molecular markers predictive of chemotherapy response in colorectal cancer.
Author:	Shiovitz, Stacey\|Grady, William M
PMID:	25663616

2215.
Journal:	World J Gastroenterol. 2015 Feb 7;21(5):1457-67.
Title:	Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.
Author:	Bae, Jeong Mo\|Lee, Tae Hun\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	25663765

2216.
Journal:	World J Gastroenterol. 2015 Feb 7;21(5):1488-97.
Title:	MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways.
Author:	Gong, Bo\|Liu, Wan-Wei\|Nie, Wen-Jing\|Li, Dong-Feng\|Xie, Zi-Jun\|Liu, Chao\|Liu, Yan-Hui\|Mei, Ping\|Li, Zi-Jun
PMID:	25663768

2217.
Journal:	World J Gastroenterol. 2015 Feb 7;21(5):1595-605.
Title:	KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients.
Author:	Ye, Ju-Xiang\|Liu, Yan\|Qin, Yun\|Zhong, Hao-Hao\|Yi, Wei-Ning\|Shi, Xue-Ying
PMID:	25663779

2218.
Journal:	Oncol Lett. 2015 Mar;9(3):1432-1438.
Title:	EGFR methylation and outcome of patients with advanced colorectal cancer treated with cetuximab.
Author:	Chiadini, Elisa\|Scarpi, Emanuela\|Passardi, Alessandro\|Calistri, Daniele\|Valgiusti, Martina\|Saragoni, Luca\|Zoli, Wainer\|Amadori, Dino\|Ulivi, Paola
PMID:	25663927

2219.
Journal:	Int J Cancer. 2015 Nov 15;137(10):2470-7.
Title:	Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab.
Author:	Tarpgaard, Line S\|Christensen, Ib J\|Hoyer-Hansen, Gunilla\|Lund, Ida K\|Guren, Tormod K\|Glimelius, Bengt\|Sorbye, Halfdan\|Tveit, Kjell M\|Nielsen, Hans Jorgen\|Moreira, Jose M A\|Pfeiffer, Per\|Brunner, Nils
PMID:	25664394

2220.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):91-8.
Title:	FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Author:	Kaczirek, Klaus\|Ciuleanu, Tudor E\|Vrbanec, Damir\|Marton, Erika\|Messinger, Diethelm\|Liegl-Atzwanger, Bernadette\|Wrba, Fritz\|Knittelfelder, Regina\|Lindner, Elisabeth\|Zielinski, Christoph C\|Streubel, Berthold\|Brodowicz, Thomas
PMID:	25666295

2221.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):81-90.
Title:	Role of first-line anti-epidermal growth factor receptor therapy compared with anti-vascular endothelial growth factor therapy in advanced colorectal cancer: a meta-analysis of randomized clinical trials.
Author:	Khattak, Muhammad A\|Martin, Hilary\|Davidson, Andrew\|Phillips, Michael
PMID:	25666296

2222.
Journal:	Cancer Discov. 2015 Apr;5(4):358-67.
Title:	Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.
Author:	Ahronian, Leanne G\|Sennott, Erin M\|Van Allen, Eliezer M\|Wagle, Nikhil\|Kwak, Eunice L\|Faris, Jason E\|Godfrey, Jason T\|Nishimura, Koki\|Lynch, Kerry D\|Mermel, Craig H\|Lockerman, Elizabeth L\|Kalsy, Anuj\|Gurski, Joseph M Jr\|Bahl, Samira\|Anderka, Kristin\|Green,
PMID:	25673644

2223.
Journal:	Springerplus. 2015 Jan 5;4:7.
Title:	Performance of a novel KRAS mutation assay for formalin-fixed paraffin embedded tissues of colorectal cancer.
Author:	Sakai, Kazuko\|Yoneshige, Azusa\|Ito, Akihiko\|Ueda, Yoji\|Kondo, Satoshi\|Nobumasa, Hitoshi\|Fujita, Yoshihiko\|Togashi, Yosuke\|Terashima, Masato\|De Velasco, Marco A\|Tomida, Shuta\|Nishio, Kazuto
PMID:	25674493

2224.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):115-22.e1-2.
Title:	Circulating Tumor Cell Enumeration in a Phase II Trial of a Four-Drug Regimen in Advanced Colorectal Cancer.
Author:	Krebs, Matthew G\|Renehan, Andrew G\|Backen, Alison\|Gollins, Simon\|Chau, Ian\|Hasan, Jurjees\|Valle, Juan W\|Morris, Karen\|Beech, Janette\|Ashcroft, Linda\|Saunders, Mark P\|Dive, Caroline
PMID:	25680623

2225.
Journal:	Hum Pathol. 2015 Apr;46(4):507-13.
Title:	Novel molecular insights from routine genotyping of colorectal carcinomas.
Author:	Stachler, Matthew D\|Rinehart, Elizabeth\|Lindeman, Neal\|Odze, Robert\|Srivastava, Amitabh
PMID:	25683705

2226.
Journal:	J Cancer Epidemiol. 2015;2015:643020.
Title:	Colorectal cancer in iran: molecular epidemiology and screening strategies.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Bonyadi, Mortaza Jabbarpour\|Asvadi Kermani, Iraj\|Farassati, Faris\|Dastgiri, Saeed
PMID:	25685149

2227.
Journal:	Cancer Res Treat. 2015 Oct;47(4):796-803.
Title:	Can Serum be Used for Analyzing the KRAS Mutation Status in Patients with Advanced Colorectal Cancer?
Author:	Kim, Seung Tae\|Chang, Won Jin\|Jin, Lihua\|Sung, Jae Sook\|Choi, Yun Ji\|Kim, Yeul Hong
PMID:	25687873

2228.
Journal:	Br J Cancer. 2015 Mar 17;112(6):1088-97.
Title:	Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.
Author:	Chen, Z-Y\|Raghav, K\|Lieu, C H\|Jiang, Z-Q\|Eng, C\|Vauthey, J-N\|Chang, G J\|Qiao, W\|Morris, J\|Hong, D\|Hoff, P\|Tran, H\|Menter, D G\|Heymach, J\|Overman, M\|Kopetz, S
PMID:	25688736

2229.
Journal:	Br J Cancer. 2015 Feb 17;112(4):720-8.
Title:	KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer.
Author:	Renaud, S\|Romain, B\|Falcoz, P-E\|Olland, A\|Santelmo, N\|Brigand, C\|Rohr, S\|Guenot, D\|Massard, G
PMID:	25688918

2230.
Journal:	Am J Clin Pathol. 2015 Mar;143(3):374-84.
Title:	Left-sided early-onset vs late-onset colorectal carcinoma: histologic, clinical, and molecular differences.
Author:	Pilozzi, Emanuela\|Maresca, Carmen\|Duranti, Enrico\|Giustiniani, Maria Cristina\|Catalanotto, Caterina\|Lucarelli, Marco\|Cogoni, Carlo\|Ferri, Mario\|Ruco, Luigi\|Zardo, Giuseppe
PMID:	25696795

2231.
Journal:	Front Oncol. 2015 Feb 2;5:13.
Title:	Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.
Author:	Pereira, Lloyd\|Mariadason, John M\|Hannan, Ross D\|Dhillon, Amardeep S
PMID:	25699236

2232.
Journal:	Updates Surg. 2015 Mar;67(1):47-53.
Title:	Role of KRAS mutation as predictor of pathologic response after neoadjuvant chemoradiation therapy for rectal cancer.
Author:	Martellucci, Jacopo\|Alemanno, Giovanni\|Castiglione, Francesca\|Bergamini, Carlo\|Valeri, Andrea
PMID:	25702261

2233.
Journal:	Eur J Surg Oncol. 2015 Apr;41(4):499-505.
Title:	Liver resection rate following downsizing chemotherapy with cetuximab in metastatic colorectal cancer: UK retrospective observational study.
Author:	Malik, H\|Khan, A Z\|Berry, D P\|Cameron, I C\|Pope, I\|Sherlock, D\|Helmy, S\|Byrne, B\|Thompson, M\|Pulfer, A\|Davidson, B
PMID:	25703078

2234.
Journal:	Analyst. 2015 Apr 21;140(8):2747-54.
Title:	KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology.
Author:	Steinbach, Christine\|Steinbrucker, Carolin\|Pollok, Sibyll\|Walther, Katharina\|Clement, Joachim H\|Chen, Yuan\|Petersen, Iver\|Cialla-May, Dana\|Weber, Karina\|Popp, Jurgen
PMID:	25706807

2235.
Journal:	Nat Med. 2015 Mar;21(3):256-62.
Title:	Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.
Author:	Matano, Mami\|Date, Shoichi\|Shimokawa, Mariko\|Takano, Ai\|Fujii, Masayuki\|Ohta, Yuki\|Watanabe, Toshiaki\|Kanai, Takanori\|Sato, Toshiro
PMID:	25706875

2236.
Journal:	APMIS. 2015 Apr;123(4):298-304.
Title:	Hyperplastic polyps of the colon and rectum - reclassification, BRAF and KRAS status in index polyps and subsequent colorectal carcinoma.
Author:	Janjua, Huma Gul Rehana\|Hogdall, Estrid\|Linnemann, Dorte
PMID:	25708741

2237.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

2238.
Journal:	Mol Cancer Res. 2015 Jun;13(6):1003-8.
Title:	AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.
Author:	Hechtman, Jaclyn F\|Sadowska, Justyna\|Huse, Jason T\|Borsu, Laetitia\|Yaeger, Rona\|Shia, Jinru\|Vakiani, Efsevia\|Ladanyi, Marc\|Arcila, Maria E
PMID:	25714871

2239.
Journal:	PLoS One. 2015 Mar 3;10(3):e0118612.
Title:	Genetic characteristics of mitochondrial DNA was associated with colorectal carcinogenesis and its prognosis.
Author:	Lee, Jae-Ho\|Hwang, Ilseon\|Kang, Yu-Na\|Choi, In-Jang\|Kim, Dae-Kwang
PMID:	25734426

2240.
Journal:	Br J Cancer. 2015 Mar 17;112(6):963-70.
Title:	Correlation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancer.
Author:	Price, T J\|Bruhn, M A\|Lee, C K\|Hardingham, J E\|Townsend, A R\|Mann, K P\|Simes, J\|Weickhardt, A\|Wrin, J W\|Wilson, K\|Gebski, V\|Van Hazel, G\|Robinson, B\|Cunningham, D\|Tebbutt, N C
PMID:	25742472

2241.
Journal:	Mol Cancer. 2015 Feb 14;14:38.
Title:	High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Author:	Ilm, Katharina\|Kemmner, Wolfgang\|Osterland, Marc\|Burock, Susen\|Koch, Gudrun\|Herrmann, Pia\|Schlag, Peter M\|Stein, Ulrike
PMID:	25742883

2242.
Journal:	Gan To Kagaku Ryoho. 2015 Feb;42(2):237-9.
Title:	[A successful multimodality therapy for a case of recurrent rectal cancer with KRAS mutation].
Author:	Watanabe, Ayako\|Inada, Ryo\|Nagasaka, Takeshi\|Yagi, Tomohiko\|Matsumoto, Hijiri\|Toshima, Toshiaki\|Mori, Yoshiko\|Kondo, Yoshitaka\|Kishimoto, Hiroyuki\|Fujiwara, Toshiyoshi
PMID:	25743147

2243.
Journal:	Anticancer Res. 2015 Mar;35(3):1683-9.
Title:	Circulating hepatocyte growth factor is correlated with resistance to cetuximab in metastatic colorectal cancer.
Author:	Yonesaka, Kimio\|Satoh, Taroh\|Ueda, Shinya\|Yoshida, Takeshi\|Takeda, Masayuki\|Shimizu, Toshio\|Okamoto, Isamu\|Nishio, Kazuto\|Tamura, Takao\|Nakagawa, Kazuhiko
PMID:	25750328

2244.
Journal:	Mol Ther Nucleic Acids. 2015 Mar 10;4:e231.
Title:	Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer.
Author:	Hiraki, Masayuki\|Nishimura, Junichi\|Takahashi, Hidekazu\|Wu, Xin\|Takahashi, Yusuke\|Miyo, Masaaki\|Nishida, Naohiro\|Uemura, Mamoru\|Hata, Taishi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Soh, Jae-Won\|Doki, Yuichiro\|Mori, Masaki\|Yamamoto, Hirofumi
PMID:	25756961

2245.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2015 Jan;44(1):55-8.
Title:	[Implementation of standard operation procedures for KRAS andBRAF gene mutation detection in colorectal cancer].
Author:	Yan, Lixu\|Liu, Yanhui\|Liu, Xunhua\|Xu, Fangping\|Zhang, Keping\|Xu, Jie\|Li, Li
PMID:	25765033

2246.
Journal:	J BUON. 2015 Jan-Feb;20(1):128-35.
Title:	KRAS discordance between primary and metastatic tumor in patients with metastatic colorectal carcinoma.
Author:	Siyar Ekinci, Ahmet\|Demirci, Umut\|Cakmak Oksuzoglu, Berna\|Ozturk, Ayse\|Esbah, Onur\|Ozatli, Tahsin\|Celik, Burcin\|Budakoglu, Burcin\|Turker, Ibrahim\|Bal, Oznur\|Turan, Nedim
PMID:	25778307

2247.
Journal:	Oncology (Williston Park). 2015 Mar;29(3):175-83.
Title:	Costs and effectiveness of genomic testing in the management of colorectal cancer.
Author:	Goldstein, Daniel A\|Shaib, Walid L\|Flowers, Christopher R
PMID:	25783977

2248.
Journal:	Int J Clin Exp Med. 2015 Jan 15;8(1):1370-5. eCollection 2015.
Title:	P53 mutations occur more commonly than KRAS mutations in colorectal adenoma.
Author:	Yan, Wen-Feng\|Wu, Gang\|Sun, Pei-Chun\|Qiu, Dong
PMID:	25785139

2249.
Journal:	Am J Surg Pathol. 2015 Aug;39(8):1140-7.
Title:	Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.
Author:	Jesinghaus, Moritz\|Wolf, Thomas\|Pfarr, Nicole\|Muckenhuber, Alexander\|Ahadova, Aysel\|Warth, Arne\|Goeppert, Benjamin\|Sers, Christine\|Kloor, Matthias\|Endris, Volker\|Stenzinger, Albrecht\|Weichert, Wilko
PMID:	25786087

2250.
Journal:	Oncotarget. 2015 Mar 30;6(9):7209-20.
Title:	Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.
Author:	Mitsuhashi, Kei\|Nosho, Katsuhiko\|Sukawa, Yasutaka\|Matsunaga, Yasutaka\|Ito, Miki\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Naito, Takafumi\|Adachi, Yasushi\|Tachibana, Mami\|Tanuma, Tokuma\|Maguchi, Hiroyuki\|Shinohara, Toshiya\|Hasegawa, Tadashi\|I
PMID:	25797243

2251.
Journal:	Transl Res. 2015 Aug;166(2):207-17.
Title:	Active immunosurveillance in the tumor microenvironment of colorectal cancer is associated with low frequency tumor budding and improved outcome.
Author:	Koelzer, Viktor H\|Dawson, Heather\|Andersson, Emilia\|Karamitopoulou, Eva\|Masucci, Giuseppe V\|Lugli, Alessandro\|Zlobec, Inti
PMID:	25797890

2252.
Journal:	Cardiovasc Intervent Radiol. 2015 Dec;38(6):1523-31.
Title:	Trans-Arterial Chemoembolization with Irinotecan-Loaded Drug-Eluting Beads (DEBIRI) and Capecitabine in Refractory Liver Prevalent Colorectal Metastases: A Phase II Single-Center Study.
Author:	Iezzi, Roberto\|Marsico, Valentina Angela\|Guerra, Alessandra\|Cerchiaro, Eleonora\|Cassano, Alessandra\|Basso, Michele\|Devicienti, Ersilia\|Rodolfino, Elena\|Barone, Carlo\|Bonomo, Lorenzo
PMID:	25799948

2253.
Journal:	Cancer Sci. 2015 Mar;106(3):324-7.
Title:	Japanese Society of Medical Oncology Clinical Guidelines: RAS (KRAS/NRAS) mutation testing in colorectal cancer patients.
Author:	Taniguchi, Hiroya\|Yamazaki, Kentaro\|Yoshino, Takayuki\|Muro, Kei\|Yatabe, Yasushi\|Watanabe, Toshiaki\|Ebi, Hiromichi\|Ochiai, Atsushi\|Baba, Eishi\|Tsuchihara, Katsuya
PMID:	25800101

2254.
Journal:	Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1724-33.
Title:	Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.
Author:	Yu, Bing\|Swatkoski, Stephen\|Holly, Alesia\|Lee, Liam C\|Giroux, Valentin\|Lee, Chih-Shia\|Hsu, Dennis\|Smith, Jordan L\|Yuen, Garmen\|Yue, Junqiu\|Ann, David K\|Simpson, R Mark\|Creighton, Chad J\|Figg, William D\|Gucek, Marjan\|Luo, Ji
PMID:	25805818

2255.
Journal:	Biomark Med. 2015;9(4):337-47.
Title:	Personalized treatment for patients with colorectal cancer: role of biomarkers.
Author:	Duffy, Michael J
PMID:	25808438

2256.
Journal:	J Thromb Haemost. 2015 Jun;13(6):998-1003.
Title:	Tumor oncogene (KRAS) status and risk of venous thrombosis in patients with metastatic colorectal cancer.
Author:	Ades, S\|Kumar, S\|Alam, M\|Goodwin, A\|Weckstein, D\|Dugan, M\|Ashikaga, T\|Evans, M\|Verschraegen, C\|Holmes, C E
PMID:	25809746

2257.
Journal:	Tumour Biol. 2015 Aug;36(8):6361-8.
Title:	Development of a gLCR-based KRAS mutation detection approach and its comparison with other screening methods.
Author:	Jenner, Stefan\|Techel, Dieter
PMID:	25813150

2258.
Journal:	Genes Dis. 2015 Mar;2(1):4-12.
Title:	Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer.
Author:	Knickelbein, Kyle\|Zhang, Lin
PMID:	25815366

2259.
Journal:	Mol Med Rep. 2015 Jul;12(1):1219-24.
Title:	Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer.
Author:	Lu, Weipeng\|Wei, Hong\|Li, Mei\|Wang, Hai\|Liu, Lina\|Zhang, Qiuping\|Liu, Lisha\|Lu, Shen
PMID:	25815786

2260.
Journal:	Oncol Rep. 2015 Jun;33(6):2719-27.
Title:	Eprobe-mediated screening system for somatic mutations in the KRAS locus.
Author:	Atsumi, Jun\|Hanami, Takeshi\|Enokida, Yasuaki\|Ogawa, Hiroomi\|Delobel, Diane\|Mitani, Yasumasa\|Kimura, Yasumasa\|Soma, Takahiro\|Tagami, Michihira\|Takase, Yoshiaki\|Ichihara, Tatsuo\|Takeyoshi, Izumi\|Usui, Kengo\|Hayashizaki, Yoshihide\|Shimizu, Kimihiro
PMID:	25823645

2261.
Journal:	Rom J Morphol Embryol. 2015;56(1):175-81.
Title:	Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer.
Author:	Zlatian, Ovidiu Mircea\|Comanescu, Maria Victoria\|Rosu, Alexandra Floriana\|Rosu, Lucica\|Cruce, Mihai\|Gaman, Alice Elena\|Calina, Cornelia Daniela\|Sfredel, Veronica
PMID:	25826503

2262.
Journal:	Exp Mol Pathol. 2015 Jun;98(3):563-7.
Title:	KRAS gene mutation in a series of unselected colorectal carcinoma patients with prognostic morphological correlations: a pyrosequencing method improved by nested PCR.
Author:	de Macedo, Mariana Petaccia\|de Melo, Fernanda Machado\|Lisboa, Bianca Cristina Garcia\|Andrade, Louise D Brot\|de Souza Begnami, Maria Dirlei Ferreira\|Junior, Samuel Aguiar\|Ribeiro, Heber Salvador de Castro\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|da Cu
PMID:	25835782

2263.
Journal:	Clin Cancer Res. 2015 Jul 1;21(13):2975-83.
Title:	Primary and Acquired Resistance of Colorectal Cancer to Anti-EGFR Monoclonal Antibody Can Be Overcome by Combined Treatment of Regorafenib with Cetuximab.
Author:	Napolitano, Stefania\|Martini, Giulia\|Rinaldi, Barbara\|Martinelli, Erika\|Donniacuo, Maria\|Berrino, Liberato\|Vitagliano, Donata\|Morgillo, Floriana\|Barra, Giusy\|De Palma, Raffaele\|Merolla, Francesco\|Ciardiello, Fortunato\|Troiani, Teresa
PMID:	25838391

2264.
Journal:	Dig Dis Sci. 2015 Aug;60(8):2477-87.
Title:	Systemic Analysis of Predictive Biomarkers for Recurrence in Colorectal Cancer Patients Treated with Curative Surgery.
Author:	Mori, Koichiro\|Toiyama, Yuji\|Saigusa, Susumu\|Fujikawa, Hiroyuki\|Hiro, Junichiro\|Kobayashi, Minako\|Ohi, Masaki\|Araki, Toshimitsu\|Inoue, Yasuhiro\|Tanaka, Koji\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	25840921

2265.
Journal:	Adv Anat Pathol. 2015 May;22(3):217-24.
Title:	Selected case from the Arkadi M. Rywlin International Pathology Slide Club: carcinoma of the transverse colon in a young girl.
Author:	Galliani, Carlos A\|Sanchez, Irene C\|D'Errico, Maria M\|Bisceglia, Michele
PMID:	25844680

2266.
Journal:	Ann Oncol. 2015 Aug;26(8):1710-4.
Title:	Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial.
Author:	Normanno, N\|Rachiglio, A M\|Lambiase, M\|Martinelli, E\|Fenizia, F\|Esposito, C\|Roma, C\|Troiani, T\|Rizzi, D\|Tatangelo, F\|Botti, G\|Maiello, E\|Colucci, G\|Ciardiello, F
PMID:	25851630

2267.
Journal:	Sci Rep. 2015 Apr 8;5:9696.
Title:	KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.
Author:	Lavrado, Joao\|Brito, Hugo\|Borralho, Pedro M\|Ohnmacht, Stephan A\|Kim, Nam-Soon\|Leitao, Clara\|Pisco, Silvia\|Gunaratnam, Mekala\|Rodrigues, Cecilia M P\|Moreira, Rui\|Neidle, Stephen\|Paulo, Alexandra
PMID:	25853628

2268.
Journal:	Cancer Sci. 2015 Jun;106(6):692-9.
Title:	Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Delta716) mice involves stromal COX-2.
Author:	Fujishita, Teruaki\|Kajino-Sakamoto, Rie\|Kojima, Yasushi\|Taketo, Makoto Mark\|Aoki, Masahiro
PMID:	25855137

2269.
Journal:	Oncoscience. 2015 Feb 9;2(2):125-30.
Title:	RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions.
Author:	de Macedo, Mariana Petaccia\|de Melo, Fernanda Machado\|Ribeiro, Julia da Silva\|de Mello, Celso Abdon Lopes\|de Souza Begnami, Maria Dirlei Ferreira\|Soares, Fernando Augusto\|Carraro, Dirce Maria\|da Cunha, Isabela Werneck
PMID:	25859555

2270.
Journal:	Gastroenterol Res Pract. 2015;2015:273489.
Title:	Does the Addition of Cetuximab to Radiochemotherapy Improve Outcome of Patients with Locally Advanced Rectal Cancer? Long-Term Results from Phase II Trials.
Author:	Kripp, M\|Horisberger, K\|Mai, S\|Kienle, P\|Gaiser, T\|Post, S\|Wenz, F\|Merx, K\|Hofheinz, R-D
PMID:	25861256

2271.
Journal:	Clin Colorectal Cancer. 2015 Sep;14(3):154-61.
Title:	A Phase II Study of Sorafenib Combined With Cetuximab in EGFR-Expressing, KRAS-Mutated Metastatic Colorectal Cancer.
Author:	Do, Khanh\|Cao, Liang\|Kang, Zhigang\|Turkbey, Baris\|Lindenberg, Maria L\|Larkins, Erin\|Holkova, Beata\|Steinberg, Seth M\|Raffeld, Mark\|Peer, Cody J\|Figg, William D\|Eugeni, Michelle\|Jacobs, Paula\|Choyke, Peter\|Wright, John J\|Doroshow, James H\|Kummar, Shivaani
PMID:	25861837

2272.
Journal:	Anticancer Res. 2015 Apr;35(4):2345-50.
Title:	BRAF V600E mutation in colorectal cancer is associated with right-sided tumours and iron deficiency anaemia.
Author:	Sideris, Michail\|Adams, Katie\|Moorhead, Jane\|Diaz-Cano, Salvador\|Bjarnason, Ingvar\|Papagrigoriadis, Savvas
PMID:	25862899

2273.
Journal:	Mol Oncol. 2015 Aug;9(7):1341-7.
Title:	KRAS as a predictor of poor prognosis and benefit from postoperative FOLFOX chemotherapy in patients with stage II and III colorectal cancer.
Author:	Deng, Yanhong\|Wang, Li\|Tan, Shuyun\|Kim, George P\|Dou, Ruoxu\|Chen, Dianke\|Cai, Yue\|Fu, Xinhui\|Wang, Lei\|Zhu, Jun\|Wang, Jianping
PMID:	25864038

2274.
Journal:	Front Genet. 2015 Mar 30;6:116.
Title:	Global impact of KRAS mutation patterns in FOLFOX treated metastatic colorectal cancer.
Author:	Zocche, David M\|Ramirez, Carolina\|Fontao, Fernando M\|Costa, Lucas D\|Redal, Maria A
PMID:	25870609

2275.
Journal:	Lancet Oncol. 2015 May;16(5):499-508.
Title:	Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blin
Author:	Tabernero, Josep\|Yoshino, Takayuki\|Cohn, Allen Lee\|Obermannova, Radka\|Bodoky, Gyorgy\|Garcia-Carbonero, Rocio\|Ciuleanu, Tudor-Eliade\|Portnoy, David C\|Van Cutsem, Eric\|Grothey, Axel\|Prausova, Jana\|Garcia-Alfonso, Pilar\|Yamazaki, Kentaro\|Clingan, Philip R\|Lo
PMID:	25877855

2276.
Journal:	BMC Cancer. 2015 Mar 14;15:125.
Title:	Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.
Author:	Birgisson, Helgi\|Edlund, Karolina\|Wallin, Ulrik\|Pahlman, Lars\|Kultima, Hanna Goransson\|Mayrhofer, Markus\|Micke, Patrick\|Isaksson, Anders\|Botling, Johan\|Glimelius, Bengt\|Sundstrom, Magnus
PMID:	25884297

2277.
Journal:	BMC Cancer. 2015 Mar 21;15:160.
Title:	Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Author:	Koelzer, Viktor H\|Herrmann, Pia\|Zlobec, Inti\|Karamitopoulou, Eva\|Lugli, Alessandro\|Stein, Ulrike
PMID:	25884643

2278.
Journal:	BMC Cancer. 2015 Apr 8;15:240.
Title:	HGUE-C-1 is an atypical and novel colon carcinoma cell line.
Author:	Grasso, Silvina\|Martinez-Lacaci, Isabel\|Barbera, Victor Manuel\|Castillejo, Adela\|Soto, Jose Luis\|Gallego-Plazas, Javier\|Lopez-Riquelme, Natividad\|Garcia-Morales, Pilar\|Mata-Balaguer, Trinidad\|Ferragut, Jose Antonio\|Saceda, Miguel
PMID:	25885658

2279.
Journal:	J Transl Med. 2015 Feb 12;13:57.
Title:	Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib.
Author:	Wong, Andrea Li Ann\|Lim, Joline Si Jing\|Sinha, Arvind\|Gopinathan, Anil\|Lim, Robert\|Tan, Chee-Seng\|Soh, Thomas\|Venkatesh, Sudhakar\|Titin, Christina\|Sapari, Nur Sabrina\|Lee, Soo-Chin\|Yong, Wei-Peng\|Tan, David Shao Ping\|Pang, Brendan\|Wang, Ting-Ting\|Zee, Yin
PMID:	25889309

2280.
Journal:	Nutr J. 2015 Apr 1;14:31.
Title:	Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells.
Author:	Tahir, Analhuda Abdullah\|Sani, Nur Fathiah Abdul\|Murad, Noor Azian\|Makpol, Suzana\|Ngah, Wan Zurinah Wan\|Yusof, Yasmin Anum Mohd
PMID:	25889965

2281.
Journal:	BMC Med. 2015 Apr 8;13:75.
Title:	Improved survival among colon cancer patients with increased differentially expressed pathways.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Mullany, Lila E\|Gertz, Jason\|Wolff, Roger K
PMID:	25890236

2282.
Journal:	BMC Cancer. 2015 Apr 17;15:301.
Title:	Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Author:	Chen, Kuen-Feng\|Yen, Chueh-Chuan\|Lin, Jen-Kou\|Chen, Wei-Shone\|Yang, Shung-Haur\|Jiang, Jeng-Kai\|Lan, Yuan-Tzu\|Lin, Chun-Chi\|Yu, Hui-Chuan\|Hsu, Hui-Mei\|Lin, Wen-Ling\|Teng, Hao-Wei
PMID:	25896895

2283.
Journal:	Theranostics. 2015 Apr 1;5(7):724-32.
Title:	Longitudinal Tracing of Spontaneous Regression and Anti-angiogenic Response of Individual Microadenomas during Colon Tumorigenesis.
Author:	Choi, Jin Woo\|Kim, Pilhan\|Kim, Jun Ki\|Kim, Yi Rang\|Fukumura, Dai\|Yun, Seok Hyun
PMID:	25897337

2284.
Journal:	Ann Nucl Med. 2015 Jul;29(6):535-42.
Title:	[(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.
Author:	McKinley, Eliot T\|Watchmaker, Jennifer M\|Chakravarthy, A Bapsi\|Meyerhardt, Jeffrey A\|Engelman, Jeffrey A\|Walker, Ronald C\|Washington, M Kay\|Coffey, Robert J\|Manning, H Charles
PMID:	25899481

2285.
Journal:	PLoS One. 2015 Apr 22;10(4):e0123902.
Title:	Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue.
Author:	Lyberopoulou, Anna\|Aravantinos, Gerasimos\|Efstathopoulos, Efstathios P\|Nikiteas, Nikolaos\|Bouziotis, Penelope\|Isaakidou, Athina\|Papalois, Apostolos\|Marinos, Evangelos\|Gazouli, Maria
PMID:	25902072

2286.
Journal:	Nat Commun. 2015 Apr 27;6:6706.
Title:	Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.
Author:	Hiraoka, Kiriko\|Inoue, Takahiro\|Taylor, Rhys Dylan\|Watanabe, Takayoshi\|Koshikawa, Nobuko\|Yoda, Hiroyuki\|Shinohara, Ken-ichi\|Takatori, Atsushi\|Sugimoto, Hirokazu\|Maru, Yoshiaki\|Denda, Tadamichi\|Fujiwara, Kyoko\|Balmain, Allan\|Ozaki, Toshinori\|Bando, Toshika
PMID:	25913614

2287.
Journal:	J Clin Oncol. 2015 Jun 1;33(16):1787-96.
Title:	Personalizing colon cancer adjuvant therapy: selecting optimal treatments for individual patients.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25918287

2288.
Journal:	Br J Cancer. 2015 Apr 28;112(9):1480-90.
Title:	MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms.
Author:	Amankwatia, E B\|Chakravarty, P\|Carey, F A\|Weidlich, S\|Steele, R J C\|Munro, A J\|Wolf, C R\|Smith, G
PMID:	25919696

2289.
Journal:	Acta Oncol. 2015 Nov;54(10):1747-53.
Title:	Neoadjuvant chemotherapy in locally advanced colon cancer. A phase II trial.
Author:	Jakobsen, Anders\|Andersen, Fahimeh\|Fischer, Anders\|Jensen, Lars H\|Jorgensen, Jens C R\|Larsen, Ole\|Lindebjerg, Jan\|Ploen, John\|Rafaelsen, Soren R\|Vilandt, Jesper
PMID:	25920359

2290.
Journal:	Nature. 2015 May 7;521(7550):43-7.
Title:	Sequential cancer mutations in cultured human intestinal stem cells.
Author:	Drost, Jarno\|van Jaarsveld, Richard H\|Ponsioen, Bas\|Zimberlin, Cheryl\|van Boxtel, Ruben\|Buijs, Arjan\|Sachs, Norman\|Overmeer, Rene M\|Offerhaus, G Johan\|Begthel, Harry\|Korving, Jeroen\|van de Wetering, Marc\|Schwank, Gerald\|Logtenberg, Meike\|Cuppen, Edwin\|Sni
PMID:	25924068

2291.
Journal:	J Clin Pathol. 2015 Aug;68(8):657-60.
Title:	Are all RAS mutations the same? Coexisting KRAS and NRAS mutations in a caecal adenocarcinoma and contiguous tubulovillous adenoma.
Author:	Vagaja, N N\|Parry, J\|McCallum, D\|Thomas, M A\|Bentel, J M
PMID:	25926041

2292.
Journal:	Onco Targets Ther. 2015 Apr 15;8:835-43.
Title:	The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab.
Author:	Zhang, Shu-Dong\|McCrudden, Cian M\|Meng, Chen\|Lin, Yao\|Kwok, Hang Fai
PMID:	25926745

2293.
Journal:	BMC Cancer. 2015 May 1;15:340.
Title:	Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages.
Author:	Li, Wenbin\|Qiu, Tian\|Zhi, Wenxue\|Shi, Susheng\|Zou, Shuangmei\|Ling, Yun\|Shan, Ling\|Ying, Jianming\|Lu, Ning
PMID:	25929517

2294.
Journal:	Oncology (Williston Park). 2015 Apr 21;29(4 Suppl 1).
Title:	(P050) Yttrium-90 Radioembolization for Unresectable, Chemorefractory Colorectal Cancer Liver Metastases in KRAS Wild-type and Mutant Patients.
Author:
PMID:	25930808

2295.
Journal:	Ecancermedicalscience. 2015 Apr 9;9:520.
Title:	Biology of colorectal cancer.
Author:	Arvelo, Francisco\|Sojo, Felipe\|Cotte, Carlos
PMID:	25932044

2296.
Journal:	Ecancermedicalscience. 2015 Apr 15;9:522.
Title:	Cancer mutation screening: Comparison of high-resolution melt analysis between two platforms.
Author:	Ebili, Henry O\|Ilyas, Mohammad
PMID:	25932046

2297.
Journal:	Mol Oncol. 2015 Aug;9(7):1434-46.
Title:	KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.
Author:	Leiser, Dominic\|Medova, Michaela\|Mikami, Kei\|Nisa, Lluis\|Stroka, Deborah\|Blaukat, Andree\|Bladt, Friedhelm\|Aebersold, Daniel M\|Zimmer, Yitzhak
PMID:	25933688

2298.
Journal:	Mol Cancer Res. 2015 Aug;13(8):1248-62.
Title:	Colorectal Carcinogenesis: Connecting K-RAS-Induced Transformation and CREB Activity In Vitro and In Vivo.
Author:	Steven, Andre\|Heiduk, Max\|Recktenwald, Christian V\|Hiebl, Bernhard\|Wickenhauser, Claudia\|Massa, Chiara\|Seliger, Barbara
PMID:	25934695

2299.
Journal:	Int J Oncol. 2015 Jul;47(1):97-105.
Title:	A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction.
Author:	Suzuki, Shun-Ichi\|Matsusaka, Satoshi\|Hirai, Mitsuharu\|Shibata, Harumi\|Takagi, Koichi\|Mizunuma, Nobuyuki\|Hatake, Kiyohiko
PMID:	25936694

2300.
Journal:	Eur J Cancer. 2015 Jul;51(10):1243-52.
Title:	FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer.
Author:	Bokemeyer, C\|Kohne, C-H\|Ciardiello, F\|Lenz, H-J\|Heinemann, V\|Klinkhardt, U\|Beier, F\|Duecker, K\|van Krieken, J H\|Tejpar, S
PMID:	25937522

2301.
Journal:	Oncotarget. 2015 Jun 20;6(17):15681-9.
Title:	RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers.
Author:	Boleij, Annemarie\|Tops, Bastiaan B J\|Rombout, Paul D M\|Dequeker, Elizabeth M\|Ligtenberg, Marjolijn J L\|van Krieken, J Han
PMID:	25944693

2302.
Journal:	PLoS One. 2015 May 6;10(5):e0126417.
Title:	Comparison of genetic and epigenetic alterations of primary tumors and matched plasma samples in patients with colorectal cancer.
Author:	Danese, Elisa\|Minicozzi, Anna Maria\|Benati, Marco\|Montagnana, Martina\|Paviati, Elisa\|Salvagno, Gian Luca\|Lima-Oliveira, Gabriel\|Gusella, Milena\|Pasini, Felice\|Lippi, Giuseppe\|Guidi, Gian Cesare
PMID:	25946211

2303.
Journal:	PLoS One. 2015 May 8;10(5):e0121891.
Title:	Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.
Author:	Sakai, Kazuko\|Tsurutani, Junji\|Yamanaka, Takeharu\|Yoneshige, Azusa\|Ito, Akihiko\|Togashi, Yosuke\|De Velasco, Marco A\|Terashima, Masato\|Fujita, Yoshihiko\|Tomida, Shuta\|Tamura, Takao\|Nakagawa, Kazuhiko\|Nishio, Kazuto
PMID:	25954997

2304.
Journal:	BMC Cancer. 2015 May 10;15:384.
Title:	Randomized phase III clinical trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or
Author:	Pectasides, Dimitrios\|Karavasilis, Vasilios\|Papaxoinis, George\|Gourgioti, Georgia\|Makatsoris, Thomas\|Raptou, Georgia\|Vrettou, Eleni\|Sgouros, Joseph\|Samantas, Epaminontas\|Basdanis, George\|Papakostas, Pavlos\|Bafaloukos, Dimitrios\|Kotoula, Vassiliki\|Kalofono
PMID:	25956750

2305.
Journal:	Breast Care (Basel). 2015 Feb;10(1):27-31.
Title:	Familial breast cancer - targeted therapy in secondary and tertiary prevention.
Author:	Kast, Karin\|Rhiem, Kerstin
PMID:	25960722

2306.
Journal:	Oncotarget. 2015 Jun 30;6(18):16059-68.
Title:	Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients.
Author:	Oh, Bo Young\|Lee, Woo Yong\|Jung, Sungwon\|Hong, Hye Kyung\|Nam, Do-Hyun\|Park, Yoon Ah\|Huh, Jung Wook\|Yun, Seong Hyeon\|Kim, Hee Cheol\|Chun, Ho-Kyung\|Cho, Yong Beom
PMID:	25965827

2307.
Journal:	Abdom Imaging. 2015 Oct;40(7):2331-7.
Title:	CT textural analysis of hepatic metastatic colorectal cancer: pre-treatment tumor heterogeneity correlates with pathology and clinical outcomes.
Author:	Lubner, Meghan G\|Stabo, Nicholas\|Lubner, Sam J\|del Rio, Alejandro Munoz\|Song, Chihwa\|Halberg, Richard B\|Pickhardt, Perry J
PMID:	25968046

2308.
Journal:	PLoS One. 2015 May 13;10(5):e0124612.
Title:	Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial.
Author:	Pentheroudakis, George\|Raptou, Georgia\|Kotoula, Vassiliki\|Wirtz, Ralph M\|Vrettou, Eleni\|Karavasilis, Vasilios\|Gourgioti, Georgia\|Gakou, Chryssa\|Syrigos, Konstantinos N\|Bournakis, Evangelos\|Rallis, Grigorios\|Varthalitis, Ioannis\|Galani, Eleni\|Lazaridis, Ge
PMID:	25970543

2309.
Journal:	Am J Clin Pathol. 2015 Jun;143(6):879-88.
Title:	Endoscopic ultrasound fine-needle aspiration cytology mutation profiling using targeted next-generation sequencing: personalized care for rectal cancer.
Author:	Gleeson, Ferga C\|Kipp, Benjamin R\|Voss, Jesse S\|Campion, Michael B\|Minot, Douglas M\|Tu, Zheng J\|Klee, Eric W\|Sciallis, Andrew P\|Graham, Rondell P\|Lazaridis, Konstantinos N\|Henry, Michael R\|Levy, Michael J
PMID:	25972331

2310.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):560-74. eCollection 2015.
Title:	Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells.
Author:	Grunt, Thomas W\|Hebar, Alexandra\|Laffer, Sylvia\|Wagner, Renate\|Peter, Barbara\|Herrmann, Harald\|Graf, Alexandra\|Bilban, Martin\|Posch, Martin\|Hoermann, Gregor\|Mayerhofer, Matthias\|Eisenwort, Gregor\|Zielinski, Christoph C\|Selzer, Edgar\|Valent, Peter
PMID:	25973297

2311.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):674-88. eCollection 2015.
Title:	A specific KRAS codon 13 mutation is an independent predictor for colorectal cancer metachronous distant metastases.
Author:	Feng, Qingyang\|Liang, Li\|Ren, Li\|Chen, Jingwen\|Wei, Ye\|Chang, Wenju\|Zhu, Dexiang\|Lin, Qi\|Zheng, Peng\|Xu, Jianmin
PMID:	25973306

2312.
Journal:	PLoS One. 2015 May 14;10(5):e0126670.
Title:	Co-evolution of somatic variation in primary and metastatic colorectal cancer may expand biopsy indications in the molecular era.
Author:	Kim, Richard\|Schell, Michael J\|Teer, Jamie K\|Greenawalt, Danielle M\|Yang, Mingli\|Yeatman, Timothy J
PMID:	25974029

2313.
Journal:	Clin Lab. 2015;61(3-4):435-9.
Title:	Comparison of high-resolution melting analysis, Sanger sequencing and ARMS for KRAS mutation detection in metastatic colorectal cancer.
Author:	Zhang, Haiyan\|Zhang, Xiaoming\|Wang, Jie\|Xian, Jiang\|Chen, Xiaodong\|Zhang, Wei
PMID:	25975014

2314.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2015 Apr;44(4):254-7.
Title:	[Detection of KRAS,NRAS and BRAF gene mutations in colorectal carcinoma].
Author:	Zhang, Keping\|Xu, Jie\|Yan, Lixu\|Liu, Xunhua\|Xu, Fangping\|Liu, Yanhui
PMID:	25975908

2315.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1130-7.
Title:	Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics.
Author:	Hardikar, Sheetal\|Newcomb, Polly A\|Campbell, Peter T\|Win, Aung Ko\|Lindor, Noralane M\|Buchanan, Daniel D\|Makar, Karen W\|Jenkins, Mark A\|Potter, John D\|Phipps, Amanda I
PMID:	25976417

2316.
Journal:	Eur J Cancer. 2015 Jul;51(11):1405-14.
Title:	Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17.
Author:	Brule, S Y\|Jonker, D J\|Karapetis, C S\|O'Callaghan, C J\|Moore, M J\|Wong, R\|Tebbutt, N C\|Underhill, Cr\|Yip, D\|Zalcberg, J R\|Tu, D\|Goodwin, R A
PMID:	25979833

2317.
Journal:	Gastroenterol Res Pract. 2015;2015:753903.
Title:	KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?
Author:	Piton, Nicolas\|Borrini, Francesco\|Bolognese, Antonio\|Lamy, Aude\|Sabourin, Jean-Christophe
PMID:	25983749

2318.
Journal:	Int J Clin Oncol. 2015 Dec;20(6):1147-55.
Title:	Gene-expression profiles correlate with the efficacy of anti-EGFR therapy and chemotherapy for colorectal cancer.
Author:	Inoue, Masahiro\|Takahashi, Shin\|Soeda, Hiroshi\|Shimodaira, Hideki\|Watanabe, Mika\|Miura, Koh\|Sasaki, Iwao\|Kato, Shunsuke\|Ishioka, Chikashi
PMID:	25990448

2319.
Journal:	Am Soc Clin Oncol Educ Book. 2015:e149-56.
Title:	Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	25993166

2320.
Journal:	Clin Transl Oncol. 2015 Sep;17(9):751-6.
Title:	RAS status in Korean patients with stage III and IV colorectal cancer.
Author:	Lee, W-S\|Lee, J N\|Baek, J-H\|Park, Y H
PMID:	25997687

2321.
Journal:	J Control Release. 2015 Jul 28;210:26-38.
Title:	Cetuximab-oxaliplatin-liposomes for epidermal growth factor receptor targeted chemotherapy of colorectal cancer.
Author:	Zalba, Sara\|Contreras, Ana M\|Haeri, Azadeh\|Ten Hagen, Timo L M\|Navarro, Inigo\|Koning, Gerben\|Garrido, Maria J
PMID:	25998052

2322.
Journal:	Hum Pathol. 2015 Jul;46(7):933-8.
Title:	Traditional serrated adenoma: an update.
Author:	Bettington, Mark L\|Chetty, Runjan
PMID:	26001333

2323.
Journal:	Med Oncol. 2015 Jul;32(7):182.
Title:	Pathological response after neoadjuvant bevacizumab- or cetuximab-based chemotherapy in resected colorectal cancer liver metastases.
Author:	Pietrantonio, Filippo\|Mazzaferro, Vincenzo\|Miceli, Rosalba\|Cotsoglou, Christian\|Melotti, Flavia\|Fanetti, Giuseppe\|Perrone, Federica\|Biondani, Pamela\|Muscara, Cecilia\|Di Bartolomeo, Maria\|Coppa, Jorgelina\|Maggi, Claudia\|Milione, Massimo\|Tamborini, Elena\|de
PMID:	26003673

2324.
Journal:	Rev Med Chil. 2015 Mar;143(3):310-9.
Title:	[Molecular analysis of sporadic colon cancer].
Author:	Hurtado, Claudia\|Wielandt, Ana Maria\|Zarate, Alejandro J\|Kronberg, Udo\|Castro, Magdalena\|Yamagiwa, Ken\|Ito, Takashi\|Eishi, Yoshinobu\|Contreras, Luis\|Lopez-Kostner, Francisco
PMID:	26005817

2325.
Journal:	Nat Cell Biol. 2015 Jun;17(6):804-15.
Title:	RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
Author:	Depeille, Philippe\|Henricks, Linda M\|van de Ven, Robert A H\|Lemmens, Ed\|Wang, Chih-Yang\|Matli, Mary\|Werb, Zena\|Haigis, Kevin M\|Donner, David\|Warren, Robert\|Roose, Jeroen P
PMID:	26005835

2326.
Journal:	PLoS One. 2015 May 26;10(5):e0127146.
Title:	Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.
Author:	Betge, Johannes\|Kerr, Grainne\|Miersch, Thilo\|Leible, Svenja\|Erdmann, Gerrit\|Galata, Christian L\|Zhan, Tianzuo\|Gaiser, Timo\|Post, Stefan\|Ebert, Matthias P\|Horisberger, Karoline\|Boutros, Michael
PMID:	26010451

2327.
Journal:	Clin Nucl Med. 2015 Aug;40(8):621-6.
Title:	Genetic Alterations in Colorectal Cancer Have Different Patterns on 18F-FDG PET/CT.
Author:	Chen, Shang-Wen\|Lin, Chien-Yu\|Ho, Cheng-Man\|Chang, Ya-Sian\|Yang, Shu-Fen\|Kao, Chia-Hung\|Chang, Jan-Gowth
PMID:	26018692

2328.
Journal:	Clin Cancer Res. 2015 Sep 15;21(18):4153-64.
Title:	Maintenance Treatment with Cetuximab and BAY86-9766 Increases Antitumor Efficacy of Irinotecan plus Cetuximab in Human Colorectal Cancer Xenograft Models.
Author:	Troiani, Teresa\|Napolitano, Stefania\|Martini, Giulia\|Martinelli, Erika\|Cardone, Claudia\|Normanno, Nicola\|Vitagliano, Donata\|Morgillo, Floriana\|Fenizia, Francesca\|Lambiase, Matilde\|Formisano, Luigi\|Bianco, Roberto\|Ciardiello, Davide\|Ciardiello, Fortunato
PMID:	26019172

2329.
Journal:	Int J Med Sci. 2015 Apr 27;12(4):349-53.
Title:	PIK3CA Amplification Is Common in Left Side-Tubular Adenomas but Uncommon Sessile Serrated Adenomas Exclusively with KRAS Mutation.
Author:	Lee, Hyunsu\|Lee, Jae-Ho\|Kim, Dae-Kwang\|Choi, In-Jang\|Hwang, Ilseon\|Kang, Yu-Na\|Kim, Shin
PMID:	26019684

2330.
Journal:	PLoS One. 2015 May 29;10(5):e0126891.
Title:	Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives.
Author:	Brito, Hugo\|Martins, Ana Claudia\|Lavrado, Joao\|Mendes, Eduarda\|Francisco, Ana Paula\|Santos, Sofia A\|Ohnmacht, Stephan A\|Kim, Nam-Soon\|Rodrigues, Cecilia M P\|Moreira, Rui\|Neidle, Stephen\|Borralho, Pedro M\|Paulo, Alexandra
PMID:	26024321

2331.
Journal:	Genomics. 2015 Aug;106(2):71-5.
Title:	Discrepancies between the K-ras mutational status of primary colorectal cancers and corresponding liver metastases are found in codon 13.
Author:	Kawamata, Hiroshi\|Yamashita, Keishi\|Kojo, Ken\|Ushiku, Hideki\|Ooki, Akira\|Watanabe, Masahiko
PMID:	26026309

2332.
Journal:	Drug Resist Updat. 2015 May;20:39-70.
Title:	Pharmacogenomics of intrinsic and acquired pharmacoresistance in colorectal cancer: Toward targeted personalized therapy.
Author:	De Mattia, Elena\|Cecchin, Erika\|Toffoli, Giuseppe
PMID:	26027741

2333.
Journal:	Oncotarget. 2015 May 10;6(13):10994-1008.
Title:	Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway.
Author:	Conti, Annalisa\|Majorini, Maria Teresa\|Elliott, Richard\|Ashworth, Alan\|Lord, Christopher J\|Cancelliere, Carlotta\|Bardelli, Alberto\|Seneci, Pierfausto\|Walczak, Henning\|Delia, Domenico\|Lecis, Daniele
PMID:	26028667

2334.
Journal:	Radiol Oncol. 2015 Mar 25;49(2):200-8.
Title:	The cost of systemic therapy for metastatic colorectal carcinoma in Slovenia: discrepancy analysis between cost and reimbursement.
Author:	Mesti, Tanja\|Boshkoska, Biljana Mileva\|Kos, Mitja\|Tekavcic, Metka\|Ocvirk, Janja
PMID:	26029033

2335.
Journal:	J Gastrointest Oncol. 2015 Jun;6(3):314-21.
Title:	Extended RAS testing in metastatic colorectal cancer-Refining the predictive molecular biomarkers.
Author:	Al-Shamsi, Humaid O\|Alhazzani, Waleed\|Wolff, Robert A
PMID:	26029459

2336.
Journal:	Nat Med. 2015 Jul;21(7):795-801.
Title:	Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Author:	Siravegna, Giulia\|Mussolin, Benedetta\|Buscarino, Michela\|Corti, Giorgio\|Cassingena, Andrea\|Crisafulli, Giovanni\|Ponzetti, Agostino\|Cremolini, Chiara\|Amatu, Alessio\|Lauricella, Calogero\|Lamba, Simona\|Hobor, Sebastijan\|Avallone, Antonio\|Valtorta, Emanuele\|R
PMID:	26030179

2337.
Journal:	Arch Pathol Lab Med. 2015 Jun;139(6):730-41.
Title:	Molecular and histologic considerations in the assessment of serrated polyps.
Author:	Yang, Hui-Min\|Mitchell, James M\|Sepulveda, Jorge L\|Sepulveda, Antonia R
PMID:	26030242

2338.
Journal:	J Surg Oncol. 2015 Jun;111(8):1059-64.
Title:	KRAS discordance between primary and recurrent tumors after radical resection of colorectal cancers.
Author:	Lee, Kyung Ha\|Kim, Jin Soo\|Lee, Choong Sik\|Kim, Ji Yeon
PMID:	26031776

2339.
Journal:	Oncotarget. 2015 May 30;6(15):13334-46.
Title:	Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer.
Author:	Gyorffy, Balazs\|Stelniec-Klotz, Iwona\|Sigler, Christian\|Kasack, Katharina\|Redmer, Torben\|Qian, Yu\|Schafer, Reinhold
PMID:	26033452

2340.
Journal:	PLoS One. 2015 Jun 4;10(6):e0128202.
Title:	Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations.
Author:	Li, Wenbin\|Zhi, Wenxue\|Zou, Shuangmei\|Qiu, Tian\|Ling, Yun\|Shan, Ling\|Shi, Susheng\|Ying, Jianming
PMID:	26042813

2341.
Journal:	Anticancer Drugs. 2015 Sep;26(8):872-7.
Title:	Safety and efficacy of the addition of simvastatin to panitumumab in previously treated KRAS mutant metastatic colorectal cancer patients.
Author:	Baas, Jara M\|Krens, Lisanne L\|Bos, Monique M\|Portielje, Johanneke E A\|Batman, Erdogan\|van Wezel, Tom\|Morreau, Hans\|Guchelaar, Henk-Jan\|Gelderblom, Hans
PMID:	26053280

2342.
Journal:	Cancer Genet. 2015 Jul-Aug;208(7-8):390-5.
Title:	Somatic c.34G>T KRAS mutation: a new prescreening test for MUTYH-associated polyposis?
Author:	Aime, Adeline\|Coulet, Florence\|Lefevre, Jeremie H\|Colas, Chrystelle\|Cervera, Pascale\|Flejou, Jean-Francois\|Lascols, Olivier\|Soubrier, Florent\|Parc, Yann
PMID:	26056087

2343.
Journal:	Onco Targets Ther. 2015 May 26;8:1229-37.
Title:	Positive feedback between oncogenic KRAS and HIF-1alpha confers drug resistance in colorectal cancer.
Author:	Wang, Yanzhao\|Lei, Fuming\|Rong, Wanshui\|Zeng, Qingmin\|Sun, Wenbing
PMID:	26060408

2344.
Journal:	Int J Clin Exp Med. 2015 Mar 15;8(3):3241-57. eCollection 2015.
Title:	Correlation between smoking history and molecular pathways in sporadic colorectal cancer: a meta-analysis.
Author:	Chen, Ke\|Xia, Guanggai\|Zhang, Changhua\|Sun, Yunwei
PMID:	26064214

2345.
Journal:	World J Gastroenterol. 2015 Jun 7;21(21):6470-8.
Title:	Different treatment strategies and molecular features between right-sided and left-sided colon cancers.
Author:	Shen, Hong\|Yang, Jiao\|Huang, Qing\|Jiang, Meng-Jie\|Tan, Yi-Nuo\|Fu, Jian-Fei\|Zhu, Li-Zhen\|Fang, Xue-Feng\|Yuan, Ying
PMID:	26074686

2346.
Journal:	Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):466-71.
Title:	Comparison of the prevalence of KRAS-LCS6 polymorphism (rs61764370) within different tumour types (colorectal, breast, non-small cell lung cancer and brain tumours). A study of the Czech population.
Author:	Uvirova, Magdalena\|Simova, Jarmila\|Kubova, Barbora\|Dvorackova, Nina\|Tomaskova, Hana\|Sedivcova, Monika\|Dite, Petr
PMID:	26077004

2347.
Journal:	Clin Colorectal Cancer. 2015 Dec;14(4):203-18.
Title:	Current and Future Approaches to Target the Epidermal Growth Factor Receptor and Its Downstream Signaling in Metastatic Colorectal Cancer.
Author:	Lee, Michael S\|Kopetz, Scott
PMID:	26077270

2348.
Journal:	Oncotarget. 2015 Oct 6;6(30):28929-37.
Title:	Identification and characterization of RET fusions in advanced colorectal cancer.
Author:	Le Rolle, Anne-France\|Klempner, Samuel J\|Garrett, Christopher R\|Seery, Tara\|Sanford, Eric M\|Balasubramanian, Sohail\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Chiu, Vi K
PMID:	26078337

2349.
Journal:	World J Gastroenterol. 2015 Jun 14;21(22):7022-35.
Title:	Standard chemotherapy with cetuximab for treatment of colorectal cancer.
Author:	Li, Xin-Xiang\|Liang, Lei\|Huang, Li-Yong\|Cai, San-Jun
PMID:	26078581

2350.
Journal:	J Exp Clin Cancer Res. 2015 Jun 18;34:63.
Title:	The mutation rates of EGFR in non-small cell lung cancer and KRAS in colorectal cancer of Chinese patients as detected by pyrosequencing using a novel dispensation order.
Author:	Xie, Guohua\|Xie, Fang\|Wu, Ping\|Yuan, Xiangliang\|Ma, Yanhui\|Xu, Yunchuan\|Li, Li\|Xu, Ling\|Yang, Ming\|Shen, Lisong
PMID:	26081767

2351.
Journal:	Autophagy. 2015;11(8):1373-88.
Title:	The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.
Author:	Wiersma, Valerie R\|de Bruyn, Marco\|Wei, Yunwei\|van Ginkel, Robert J\|Hirashima, Mitsuomi\|Niki, Toshiro\|Nishi, Nozomu\|Zhou, Jin\|Pouwels, Simon D\|Samplonius, Douwe F\|Nijman, Hans W\|Eggleton, Paul\|Helfrich, Wijnand\|Bremer, Edwin
PMID:	26086204

2352.
Journal:	World J Gastrointest Oncol. 2015 Jun 15;7(6):47-54.
Title:	Locoregional therapy and systemic cetuximab to treat colorectal liver metastases.
Author:	Fiorentini, Giammaria\|Aliberti, Camillo\|Sarti, Donatella\|Coschiera, Paolo\|Tilli, Massimo\|Mulazzani, Luca\|Giordani, Paolo\|Graziano, Francesco\|Gonzalez, Alfonso Marques\|Marcos, Raul Garcia\|Mugnoz, Fernando Gomez\|Cantore, Maurizio\|Ricci, Stefano\|Catalano, Vi
PMID:	26090075

2353.
Journal:	Cell. 2015 Jun 18;161(7):1539-1552.
Title:	Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.
Author:	Dow, Lukas E\|O'Rourke, Kevin P\|Simon, Janelle\|Tschaharganeh, Darjus F\|van Es, Johan H\|Clevers, Hans\|Lowe, Scott W
PMID:	26091037

2354.
Journal:	Pathol Res Pract. 2015 Aug;211(8):601-9.
Title:	Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system.
Author:	Michl, Marlies\|Heinemann, Volker\|Jung, Andreas\|Engel, Jutta\|Kirchner, Thomas\|Neumann, Jens
PMID:	26092596

2355.
Journal:	Radiother Oncol. 2015 Sep;116(3):510-6.
Title:	EGFR and beta1-integrin targeting differentially affect colorectal carcinoma cell radiosensitivity and invasion.
Author:	Poschau, Mandy\|Dickreuter, Ellen\|Singh-Muller, Jenny\|Zscheppang, Katja\|Eke, Iris\|Liersch, Torsten\|Cordes, Nils
PMID:	26096850

2356.
Journal:	PLoS One. 2015 Jun 22;10(6):e0131108.
Title:	A Transition Zone Showing Highly Discontinuous or Alternating Levels of Stem Cell and Proliferation Markers Characterizes the Development of PTEN-Haploinsufficient Colorectal Cancer.
Author:	Arvai, Kevin J\|Hsu, Ya-Hsuan\|Lee, Lobin A\|Jones, Dan
PMID:	26098881

2357.
Journal:	J Transl Med. 2015 Jun 24;13:199.
Title:	The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts.
Author:	le Rolle, Anne-France\|Chiu, Thang K\|Fara, Michael\|Shia, Jinru\|Zeng, Zhaoshi\|Weiser, Martin R\|Paty, Philip B\|Chiu, Vi K
PMID:	26104296

2358.
Journal:	Biomed Res Int. 2015;2015:185404.
Title:	Lack of Association between Membrane-Type 1 Matrix Metalloproteinase Expression and Clinically Relevant Molecular or Morphologic Tumor Characteristics at the Leading Edge of Invasive Colorectal Carcinoma.
Author:	Arndt, Annette\|Kraft, Klaus\|Wardelmann, Eva\|Steinestel, Konrad
PMID:	26106602

2359.
Journal:	Medicine (Baltimore). 2015 Jun;94(25):e908.
Title:	Prognostic Significance of Statin Use in Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author:	Ling, Ying\|Yang, Li\|Huang, Huiqiao\|Hu, Xiaohua\|Zhao, Cuisong\|Huang, Hongyan\|Ying, Yanping
PMID:	26107680

2360.
Journal:	World J Gastroenterol. 2015 Jun 21;21(23):7281-8.
Title:	Bevacizumab plus XELOX as first-line treatment of metastatic colorectal cancer: The OBELIX study.
Author:	Antonuzzo, Lorenzo\|Giommoni, Elisa\|Pastorelli, Davide\|Latiano, Tiziana\|Pavese, Ida\|Azzarello, Domenico\|Aieta, Michele\|Pastina, Ilaria\|Di Fabio, Francesca\|Bertolini, Alessandro\|Corsi, Domenico Cristiano\|Mogavero, Selene\|Angelini, Valentina\|Pazzagli, Mario\|
PMID:	26109816

2361.
Journal:	PLoS One. 2015 Jun 25;10(6):e0130543.
Title:	EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells.
Author:	Roda, Desamparados\|Castillo, Josefa\|Telechea-Fernandez, Marcelino\|Gil, Anabel\|Lopez-Rodas, Gerardo\|Franco, Luis\|Gonzalez-Rodriguez, Patricia\|Rosello, Susana\|Perez-Fidalgo, J Alejandro\|Garcia-Trevijano, Elena R\|Cervantes, Andres\|Zaragoza, Rosa
PMID:	26110767

2362.
Journal:	Br J Cancer. 2015 Jun 30;113(1):1-5.
Title:	Stem vs non-stem cell origin of colorectal cancer.
Author:	Huels, D J\|Sansom, O J
PMID:	26110974

2363.
Journal:	Redox Biol. 2015 Aug;5:319-27.
Title:	Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor beta-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells.
Author:	Hrabe, Jennifer E\|O'Leary, Brianne R\|Fath, Melissa A\|Rodman, Samuel N\|Button, Anna M\|Domann, Frederick E\|Spitz, Douglas R\|Mezhir, James J
PMID:	26114584

2364.
Journal:	Pathol Res Pract. 2015 Sep;211(9):646-51.
Title:	KRAS and aneusomy of chromosomes 4, 10 and 12 in colorectal carcinomas.
Author:	Beyer, Kristin\|Altendorf-Hofmann, Annelore\|Chen, Yuan\|Bickel, Klaus\|Petersen, Iver
PMID:	26122820

2365.
Journal:	Elife. 2015 Jul 1;4:e07197.
Title:	KRAS-dependent sorting of miRNA to exosomes.
Author:	Cha, Diana J\|Franklin, Jeffrey L\|Dou, Yongchao\|Liu, Qi\|Higginbotham, James N\|Demory Beckler, Michelle\|Weaver, Alissa M\|Vickers, Kasey\|Prasad, Nirpesh\|Levy, Shawn\|Zhang, Bing\|Coffey, Robert J\|Patton, James G
PMID:	26132860

2366.
Journal:	J Hum Genet. 2015 Oct;60(10):589-96.
Title:	Genetic mutations in human rectal cancers detected by targeted sequencing.
Author:	Bai, Jun\|Gao, Jinglong\|Mao, Zhijun\|Wang, Jianhua\|Li, Jianhui\|Li, Wensheng\|Lei, Yu\|Li, Shuaishuai\|Wu, Zhuo\|Tang, Chuanning\|Jones, Lindsey\|Ye, Hua\|Lou, Feng\|Liu, Zhiyuan\|Dong, Zhishou\|Guo, Baishuai\|Huang, Xue F\|Chen, Si-Yi\|Zhang, Enke
PMID:	26134512

2367.
Journal:	J Nucl Med. 2015 Sep;56(9):1322-7.
Title:	Relationship Between 18F-FDG PET/CT Scans and KRAS Mutations in Metastatic Colorectal Cancer.
Author:	Kawada, Kenji\|Toda, Kosuke\|Nakamoto, Yuji\|Iwamoto, Masayoshi\|Hatano, Etsuro\|Chen, Fengshi\|Hasegawa, Suguru\|Togashi, Kaori\|Date, Hiroshi\|Uemoto, Shinji\|Sakai, Yoshiharu
PMID:	26135109

2368.
Journal:	Front Pharmacol. 2015 Jun 16;6:120.
Title:	Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.
Author:	Davis, S Lindsey\|Robertson, Kelli M\|Pitts, Todd M\|Tentler, John J\|Bradshaw-Pierce, Erica L\|Klauck, Peter J\|Bagby, Stacey M\|Hyatt, Stephanie L\|Selby, Heather M\|Spreafico, Anna\|Ecsedy, Jeffrey A\|Arcaroli, John J\|Messersmith, Wells A\|Tan, Aik Choon\|Eckhardt,
PMID:	26136684

2369.
Journal:	EBioMedicine. 2015 Feb 14;2(4):317-23.
Title:	Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study.
Author:	Yoshino, Takayuki\|Muro, Kei\|Yamaguchi, Kensei\|Nishina, Tomohiro\|Denda, Tadamichi\|Kudo, Toshihiro\|Okamoto, Wataru\|Taniguchi, Hiroya\|Akagi, Kiwamu\|Kajiwara, Takeshi\|Hironaka, Shuichi\|Satoh, Taroh
PMID:	26137573

2370.
Journal:	Crit Rev Oncol Hematol. 2015 Nov;96(2):355-71.
Title:	Risk of grade 3-4 diarrhea and mucositis in colorectal cancer patients receiving anti-EGFR monoclonal antibodies regimens: A meta-analysis of 18 randomized controlled clinical trials.
Author:	Miroddi, Marco\|Sterrantino, Carmelo\|Simonelli, Ilaria\|Ciminata, Giorgio\|Phillips, Robert S\|Calapai, Gioacchino
PMID:	26160607

2371.
Journal:	Folia Histochem Cytobiol. 2015;53(2):105-19.
Title:	The Hippo pathway in colorectal cancer.
Author:	Wierzbicki, Piotr M\|Rybarczyk, Agnieszka
PMID:	26160682

2372.
Journal:	J Natl Cancer Inst. 2015 Jul 9;107(10). pii: djv186.
Title:	Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients.
Author:	Yoon, Harry H\|Shi, Qian\|Alberts, Steven R\|Goldberg, Richard M\|Thibodeau, Stephen N\|Sargent, Daniel J\|Sinicrope, Frank A
PMID:	26160882

2373.
Journal:	Future Oncol. 2015;11(13):1919-29.
Title:	KRAS exon 2 mutations influence activity of regorafenib in an SW48-based disease model of colorectal cancer.
Author:	Camaj, Peter\|Primo, Stefano\|Wang, Yan\|Heinemann, Volker\|Zhao, Yue\|Laubender, Ruediger Paul\|Stintzing, Sebastian\|Giessen-Jung, Clemens\|Jung, Andreas\|Gamba, Sebastian\|Bruns, Christiane Josephine\|Modest, Dominik Paul
PMID:	26161928

2374.
Journal:	Ann Oncol. 2015 Sep;26(9):1936-41.
Title:	Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.
Author:	Sclafani, F\|Chau, I\|Cunningham, D\|Peckitt, C\|Lampis, A\|Hahne, J C\|Braconi, C\|Tabernero, J\|Glimelius, B\|Cervantes, A\|Begum, R\|Gonzalez De Castro, D\|Hulkki Wilson, S\|Eltahir, Z\|Wotherspoon, A\|Tait, D\|Brown, G\|Oates, J\|Valeri, N
PMID:	26162609

2375.
Journal:	Exp Mol Pathol. 2015 Oct;99(2):207-11.
Title:	Development of pyrosequencing methods for the rapid detection of RAS mutations in clinical samples.
Author:	Cortes, Ulrich\|Guilloteau, Karline\|Rouvreau, Melanie\|Archaimbault, Celine\|Villalva, Claire\|Karayan-Tapon, Lucie
PMID:	26163758

2376.
Journal:	Anticancer Res. 2015 Aug;35(8):4453-9.
Title:	Establishment of a Three-dimensional Floating Cell Culture System for Screening Drugs Targeting KRAS-mediated Signaling Molecules.
Author:	Tsunoda, Toshiyuki\|Ishikura, Shuhei\|Doi, Keiko\|Iwaihara, Yuri\|Hidesima, Hiromasa\|Luo, Hao\|Hirose, Yumiko\|Shirasawa, Senji
PMID:	26168486

2377.
Journal:	Anal Bioanal Chem. 2015 Nov;407(27):8321-31.
Title:	In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.
Author:	Yosef, Hesham K\|Mavarani, Laven\|Maghnouj, Abdelouahid\|Hahn, Stephan\|El-Mashtoly, Samir F\|Gerwert, Klaus
PMID:	26168967

2378.
Journal:	Genes Chromosomes Cancer. 2015 Sep;54(9):527-41.
Title:	Gene expression in colon cancer: A focus on tumor site and molecular phenotype.
Author:	Slattery, Martha L\|Pellatt, Daniel F\|Mullany, Lila E\|Wolff, Roger K\|Herrick, Jennifer S
PMID:	26171582

2379.
Journal:	Oncotarget. 2015 Sep 15;6(27):23820-36.
Title:	LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer.
Author:	Zhuo, Changhua\|Li, Qingguo\|Wu, Yuchen\|Li, Yiwei\|Nie, Jia\|Li, Dawei\|Peng, Junjie\|Lian, Peng\|Li, Bin\|Cai, Guoxiang\|Li, Xinxiang\|Cai, Sanjun
PMID:	26172297

2380.
Journal:	JAMA Oncol. 2015 Aug;1(5):653-61.
Title:	Fusobacterium nucleatum and T Cells in Colorectal Carcinoma.
Author:	Mima, Kosuke\|Sukawa, Yasutaka\|Nishihara, Reiko\|Qian, Zhi Rong\|Yamauchi, Mai\|Inamura, Kentaro\|Kim, Sun A\|Masuda, Atsuhiro\|Nowak, Jonathan A\|Nosho, Katsuhiko\|Kostic, Aleksandar D\|Giannakis, Marios\|Watanabe, Hideo\|Bullman, Susan\|Milner, Danny A\|Harris, Curti
PMID:	26181352

2381.
Journal:	Dan Med J. 2015 Jul;62(7).
Title:	Computed tomography assessment of early response to neoadjuvant therapy in colon cancer.
Author:	Dam, Claus\|Lund-Rasmussen, Vera\|Ploen, John\|Jakobsen, Anders\|Rafaelsen, Soren Rafael
PMID:	26183044

2382.
Journal:	Cancer Lett. 2015 Oct 10;367(1):34-42.
Title:	Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors.
Author:	Lee, Sun-Hwa\|Hong, Jun Hwa\|Park, Hwan Ki\|Park, Jun Seok\|Kim, Bo-Kyung\|Lee, Jung-Yi\|Jeong, Ji Yun\|Yoon, Ghil Suk\|Inoue, Masahiro\|Choi, Gyu-Seog\|Lee, In-Kyu
PMID:	26185002

2383.
Journal:	Clin Cancer Res. 2015 Dec 1;21(23):5294-304.
Title:	Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance).
Author:	Sinicrope, Frank A\|Mahoney, Michelle R\|Yoon, Harry H\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Goldberg, Richard M\|Nelson, Garth D\|Sargent, Daniel J\|Alberts, Steven R
PMID:	26187617

2384.
Journal:	Expert Opin Ther Targets. 2015;19(12):1705-23.
Title:	MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer.
Author:	Jafri, Mohammad Alam\|Zaidi, Syed Kashif\|Ansari, Shakeel Ahmed\|Al-Qahtani, Mohammed Hussein\|Shay, Jerry W
PMID:	26189482

2385.
Journal:	Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1416-8.
Title:	Real-Life Distribution of KRAS and NRAS Mutations in Metastatic Colorectal Carcinoma from French Routine Genotyping.
Author:	Piton, Nicolas\|Lonchamp, Etienne\|Nowak, Frederique\|Sabourin, Jean-Christophe
PMID:	26189770

2386.
Journal:	Oncotarget. 2015 Sep 22;6(28):25368-80.
Title:	Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer.
Author:	Jung, Yeonjoo\|Jun, Yukyung\|Lee, Hee-Young\|Kim, Suyeon\|Jung, Yeonhwa\|Keum, Juhee\|Lee, Yeo Song\|Cho, Yong Beom\|Lee, Sanghyuk\|Kim, Jaesang
PMID:	26196590

2387.
Journal:	Gan To Kagaku Ryoho. 2015 Jul;42(7):875-7.
Title:	[A Case of Rectal Cancer with Portal Vein Tumor Thrombosis Successfully Treated with First-Line Panitumumab Monotherapy].
Author:	Takahara, Bunji\|Mima, Atsushi\|Sasaki, Kiyomi\|Mima, Kazumasa
PMID:	26197754

2388.
Journal:	Am J Surg Pathol. 2015 Oct;39(10):1340-6.
Title:	Tumor Budding in Colorectal Carcinoma: Confirmation of Prognostic Significance and Histologic Cutoff in a Population-based Cohort.
Author:	Graham, Rondell P\|Vierkant, Robert A\|Tillmans, Lori S\|Wang, Alice H\|Laird, Peter W\|Weisenberger, Daniel J\|Lynch, Charles F\|French, Amy J\|Slager, Susan L\|Raissian, Yassaman\|Garcia, Joaquin J\|Kerr, Sarah E\|Lee, Hee Eun\|Thibodeau, Stephen N\|Cerhan, James R\|L
PMID:	26200097

2389.
Journal:	Br J Surg. 2015 Sep;102(10):1175-83.
Title:	Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases.
Author:	Brudvik, K W\|Kopetz, S E\|Li, L\|Conrad, C\|Aloia, T A\|Vauthey, J-N
PMID:	26206254

2390.
Journal:	Mol Cancer Ther. 2015 Oct;14(10):2175-86.
Title:	Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.
Author:	Raja, Meera\|Zverev, Matt\|Seipel, Katja\|Williams, Geraint T\|Clarke, Alan R\|Shaw, Paul H S
PMID:	26206338

2391.
Journal:	J Vasc Interv Radiol. 2015 Aug;26(8):1102-11.
Title:	KRAS Status as an Independent Prognostic Factor for Survival after Yttrium-90 Radioembolization Therapy for Unresectable Colorectal Cancer Liver Metastases.
Author:	Lahti, Steven J\|Xing, Minzhi\|Zhang, Di\|Lee, James J\|Magnetta, Michael J\|Kim, Hyun S
PMID:	26210240

2392.
Journal:	Gastroenterology. 2015 Oct;149(5):1177-1190.e3.
Title:	Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer.
Author:	Carethers, John M\|Jung, Barbara H
PMID:	26216840

2393.
Journal:	Cancer. 2015 Nov 1;121(21):3799-808.
Title:	Molecular markers and pathway analysis of colorectal carcinoma in the Middle East.
Author:	Beg, Shaham\|Siraj, Abdul K\|Prabhakaran, Sarita\|Bu, Rong\|Al-Rasheed, Maha\|Sultana, Mehar\|Qadri, Zeeshan\|Al-Assiri, Mohammed\|Sairafi, Rami\|Al-Dayel, Fouad\|Al-Sanea, Nasser\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	26218848

2394.
Journal:	Diagn Pathol. 2015 Jul 30;10:132.
Title:	Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique.
Author:	Kriegsmann, Mark\|Arens, Norbert\|Endris, Volker\|Weichert, Wilko\|Kriegsmann, Jorg
PMID:	26220423

2395.
Journal:	PLoS One. 2015 Jul 29;10(7):e0131421.
Title:	Focus on 16p13.3 Locus in Colon Cancer.
Author:	Mampaey, Evi\|Fieuw, Annelies\|Van Laethem, Thalia\|Ferdinande, Liesbeth\|Claes, Kathleen\|Ceelen, Wim\|Van Nieuwenhove, Yves\|Pattyn, Piet\|De Man, Marc\|De Ruyck, Kim\|Van Roy, Nadine\|Geboes, Karen\|Laurent, Stephanie
PMID:	26222184

2396.
Journal:	PLoS One. 2015 Jul 29;10(7):e0133901.
Title:	An Integrative Approach for Mapping Differentially Expressed Genes and Network Components Using Novel Parameters to Elucidate Key Regulatory Genes in Colorectal Cancer.
Author:	Sehgal, Manika\|Gupta, Rajinder\|Moussa, Ahmed\|Singh, Tiratha Raj
PMID:	26222778

2397.
Journal:	Mod Pathol. 2015 Oct;28(10):1390-9.
Title:	Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers.
Author:	Haley, Lisa\|Tseng, Li-Hui\|Zheng, Gang\|Dudley, Jonathan\|Anderson, Derek A\|Azad, Nilofer S\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26226847

2398.
Journal:	Cancer Genet. 2015 Sep;208(9):441-7.
Title:	Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author:	Hagemann, Ian S\|O'Neill, Patrick K\|Erill, Ivan\|Pfeifer, John D
PMID:	26227479

2399.
Journal:	BMC Cancer. 2015 Aug 1;15:567.
Title:	Durable recurrence-free survival after pneumonectomy for late lung metastasis from rectal cancer: case report with genetic and epigenetic analyses.
Author:	Imperatori, Andrea\|Rotolo, Nicola\|Dominioni, Lorenzo\|Nardecchia, Elisa\|Cattoni, Maria\|Cimetti, Laura\|Riva, Cristina\|Sessa, Fausto\|Furlan, Daniela
PMID:	26231173

2400.
Journal:	J Clin Pathol. 2015 Dec;68(12):1044.
Title:	Coexisting KRAS and NRAS mutations in colon cancer.
Author:	Sorscher, Steven
PMID:	26243064

2401.
Journal:	Cancer Discov. 2015 Aug;5(8):832-41.
Title:	HER2 activating mutations are targets for colorectal cancer treatment.
Author:	Kavuri, Shyam M\|Jain, Naveen\|Galimi, Francesco\|Cottino, Francesca\|Leto, Simonetta M\|Migliardi, Giorgia\|Searleman, Adam C\|Shen, Wei\|Monsey, John\|Trusolino, Livio\|Jacobs, Samuel A\|Bertotti, Andrea\|Bose, Ron
PMID:	26243863

2402.
Journal:	J Biol Chem. 2015 Sep 25;290(39):23838-49.
Title:	The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
Author:	Zaanan, Aziz\|Okamoto, Koichi\|Kawakami, Hisato\|Khazaie, Khashayarsha\|Huang, Shengbing\|Sinicrope, Frank A
PMID:	26245900

2403.
Journal:	Cancer Biol Ther. 2015;16(9):1289-95.
Title:	Detection of KRAS mutations in circulating tumor cells from patients with metastatic colorectal cancer.
Author:	Buim, Marcilei Ec\|Fanelli, Marcello F\|Souza, Virgilio S\|Romero, Juliana\|Abdallah, Emne A\|Mello, Celso Al\|Alves, Vanessa\|Ocea, Luciana Mm\|Mingues, Natalia B\|Barbosa, Paula Nvp\|Tyng, Chiang J\|Chojniak, Rubens\|Chinen, Ludmilla Td
PMID:	26252055

2404.
Journal:	Medicine (Baltimore). 2015 Aug;94(31):e1284.
Title:	KRAS Mutation Status Is Not a Predictor for Tumor Response and Survival in Rectal Cancer Patients Who Received Preoperative Radiotherapy With 5-Fluoropyrimidine Followed by Curative Surgery.
Author:	Lee, Jeong Won\|Lee, Jong Hoon\|Shim, Byoung Yong\|Kim, Sung Hwan\|Chung, Mi-Joo\|Kye, Bong-Hyeon\|Kim, Hyung Jin\|Cho, Hyeon Min\|Jang, Hong Seok
PMID:	26252300

2405.
Journal:	Oncogenesis. 2015 Aug 10;4:e162.
Title:	SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
Author:	Tiwari, R\|Pandey, S K\|Goel, S\|Bhatia, V\|Shukla, S\|Jing, X\|Dhanasekaran, S M\|Ateeq, B
PMID:	26258891

2406.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5499-5510.
Title:	MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer.
Author:	Garcia-Garcia, Celina\|Rivas, Martin A\|Ibrahim, Yasir H\|Calvo, Maria Teresa\|Gris-Oliver, Albert\|Rodriguez, Olga\|Grueso, Judit\|Anton, Pilar\|Guzman, Marta\|Aura, Claudia\|Nuciforo, Paolo\|Jessen, Katti\|Argiles, Guillem\|Dienstmann, Rodrigo\|Bertotti, Andrea\|Truso
PMID:	26272063

2407.
Journal:	Cancer Prev Res (Phila). 2015 Oct;8(10):952-61.
Title:	Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence.
Author:	Hadac, Jamie N\|Leystra, Alyssa A\|Paul Olson, Terrah J\|Maher, Molly E\|Payne, Susan N\|Yueh, Alexander E\|Schwartz, Alexander R\|Albrecht, Dawn M\|Clipson, Linda\|Pasch, Cheri A\|Matkowskyj, Kristina A\|Halberg, Richard B\|Deming, Dustin A
PMID:	26276752

2408.
Journal:	J Cancer. 2015 Jul 15;6(9):825-31.
Title:	Hypothesis: Obesity Is Associated with a Lower Mutation Threshold in Colon Cancer.
Author:	Bordonaro, Michael\|Lazarova, Darina
PMID:	26284133

2409.
Journal:	PLoS One. 2015 Aug 20;10(8):e0133836.
Title:	Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas.
Author:	Patai, Arpad V\|Valcz, Gabor\|Hollosi, Peter\|Kalmar, Alexandra\|Peterfia, Balint\|Patai, Arpad\|Wichmann, Barnabas\|Spisak, Sandor\|Bartak, Barbara Kinga\|Leiszter, Katalin\|Toth, Kinga\|Sipos, Ferenc\|Kovalszky, Ilona\|Peter, Zoltan\|Miheller, Pal\|Tulassay, Zsolt\|Mol
PMID:	26291085

2410.
Journal:	Oncotarget. 2015 Aug 28;6(25):20785-800.
Title:	Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance.
Author:	Morkel, Markus\|Riemer, Pamela\|Blaker, Hendrik\|Sers, Christine
PMID:	26299805

2411.
Journal:	Mol Biol (Mosk). 2015 Jul-Aug;49(4):617-27.
Title:	[Biochip detection of KRAS, BRAF, and PIK3CA somatic mutations in colorectal cancer patients].
Author:	Emelyanova, M A\|Amossenko, F A\|Semyanikhina, A V\|Aliev, V A\|Barsukov, Yu A\|Lyubchenko, L N\|Nasedkina, T V
PMID:	26299862

2412.
Journal:	Br J Cancer. 2015 Sep 15;113(6):979-88.
Title:	Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer.
Author:	Jorissen, Robert N\|Christie, Michael\|Mouradov, Dmitri\|Sakthianandeswaren, Anuratha\|Li, Shan\|Love, Christopher\|Xu, Zheng-Zhou\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Ward, Robyn L\|Hawkins, Nicholas J\|Ruszkiewicz, Andrew R\|Moore, James\|Burgess, Ant
PMID:	26305864

2413.
Journal:	Int J Clin Exp Med. 2015 Jun 15;8(6):10168-77. eCollection 2015.
Title:	K-ras genetic mutation and influencing factor analysis for Han and Uygur nationality colorectal cancer patients.
Author:	Eli, Mayinur\|Mollayup, Ablikim\|Muattar\|Liu, Chao\|Zheng, Chao\|Bao, Yong-Xing
PMID:	26309716

2414.
Journal:	Virchows Arch. 2015 Oct;467(4):383-92.
Title:	KRAS mutations in microsatellite instable gastric tumours: impact of targeted treatment and intratumoural heterogeneity.
Author:	Queiros, Pedro\|Pinheiro, Hugo\|Carvalho, Joana\|Oliveira, Patricia\|Gullo, Irene\|Carneiro, Fatima\|Almeida, Gabriela M\|Oliveira, Carla
PMID:	26318594

2415.
Journal:	J Mol Diagn. 2015 Nov;17(6):705-14.
Title:	MSIplus for Integrated Colorectal Cancer Molecular Testing by Next-Generation Sequencing.
Author:	Hempelmann, Jennifer A\|Scroggins, Sheena M\|Pritchard, Colin C\|Salipante, Stephen J
PMID:	26322950

2416.
Journal:	Br J Cancer. 2015 Sep 15;113(6):914-20.
Title:	KRAS, NRAS, BRAF mutation comparison of endoscopic and surgically removed primary CRC paired samples: is endoscopy biopsy material adequate for molecular evaluation?
Author:	Saridaki, Z\|Saegart, X\|De Vriendt, V\|Hatzidaki, D\|Palmans, S\|De Smedt, L\|De Hertogh, G\|Tejpar, S
PMID:	26325103

2417.
Journal:	Ther Adv Med Oncol. 2015 Sep;7(5):252-62.
Title:	Precision medicine in colorectal cancer: the molecular profile alters treatment strategies.
Author:	Tran, Nguyen H\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Clipson, Linda\|Matkowskyj, Kristina A\|Deming, Dustin A
PMID:	26327923

2418.
Journal:	Am J Cancer Res. 2015 Jun 15;5(7):2241-8. eCollection 2015.
Title:	ITF-2B protein levels are correlated with favorable prognosis in patients with colorectal carcinomas.
Author:	Brandl, Lydia\|Horst, David\|de Toni, Enrico\|Kirchner, Thomas\|Herbst, Andreas\|Kolligs, Frank T
PMID:	26328254

2419.
Journal:	Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1067-74.
Title:	Phase II Trial of S-1 and Oxaliplatin Plus Cetuximab for Colorectal Cancer Patients with Initially Unresectable or Not Optimally Resectable Liver Metastases (KSCC1002).
Author:	Oki, Eiji\|Emi, Yasunori\|Miyamoto, Yuji\|Kabashima, Akira\|Higashi, Hidefumi\|Ogata, Yutaka\|Ikebe, Masahiko\|Saeki, Hiroshi\|Tokunaga, Shoji\|Shirabe, Ken\|Beppu, Toru\|Uchida, Shinji\|Takatsuki, Mitsuhisa\|Sakoda, Masahiko\|Eguchi, Susumu\|Akagi, Yoshito\|Kakeji, Yosh
PMID:	26334293

2420.
Journal:	J Transl Med. 2015 Sep 3;13:287.
Title:	The Italian external quality assessment for RAS testing in colorectal carcinoma identifies methods-related inter-laboratory differences.
Author:	Normanno, Nicola\|Pinto, Carmine\|Castiglione, Francesca\|Fenizia, Francesca\|Barberis, Massimo\|Marchetti, Antonio\|Fontanini, Gabriella\|De Rosa, Gaetano\|Taddei, Gian Luigi
PMID:	26335936

2421.
Journal:	Oncotarget. 2015 Sep 29;6(29):27725-35.
Title:	Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinoma.
Author:	Kim, Tae-Min\|An, Chang Hyeok\|Rhee, Je-Keun\|Jung, Seung-Hyun\|Lee, Sung Hak\|Baek, In-Pyo\|Kim, Min Sung\|Lee, Sug Hyung\|Chung, Yeun-Jun
PMID:	26336987

2422.
Journal:	Gastroenterol Rep (Oxf). 2015 Nov;3(4):269-76.
Title:	Molecular phenotypes of colorectal cancer and potential clinical applications.
Author:	Kocarnik, Jonathan M\|Shiovitz, Stacey\|Phipps, Amanda I
PMID:	26337942

2423.
Journal:	Drugs. 2015 Oct;75(15):1739-56.
Title:	Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.
Author:	Boeckx, Nele\|Peeters, Marc\|Van Camp, Guy\|Pauwels, Patrick\|Op de Beeck, Ken\|Deschoolmeester, Vanessa
PMID:	26347132

2424.
Journal:	Hum Pathol. 2015 Nov;46(11):1573-81.
Title:	Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers.
Author:	Koelzer, Viktor Hendrik\|Huber, Bettina\|Mele, Valentina\|Iezzi, Giandomenica\|Trippel, Mafalda\|Karamitopoulou, Eva\|Zlobec, Inti\|Lugli, Alessandro
PMID:	26351067

2425.
Journal:	Mol Cancer Ther. 2015 Dec;14(12):2700-11.
Title:	Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors.
Author:	Whittaker, Steven R\|Cowley, Glenn S\|Wagner, Steve\|Luo, Flora\|Root, David E\|Garraway, Levi A
PMID:	26351322

2426.
Journal:	Pathology. 2015 Oct;47(6):551-6.
Title:	KRAS, NRAS, BRAF mutations and high counts of poorly differentiated clusters of neoplastic cells in colorectal cancer: observational analysis of 175 cases.
Author:	Barresi, Valeria\|Bonetti, Luca Reggiani\|Bettelli, Stefania
PMID:	26352110

2427.
Journal:	Int J Colorectal Dis. 2015 Dec;30(12):1653-7.
Title:	Young age of onset colorectal cancers.
Author:	Liang, Jennifer\|Kalady, Matthew F\|Church, James
PMID:	26358068

2428.
Journal:	Cancer Gene Ther. 2015 Sep;22(9):417-30.
Title:	A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.
Author:	Dietel, M\|Johrens, K\|Laffert, M V\|Hummel, M\|Blaker, H\|Pfitzner, B M\|Lehmann, A\|Denkert, C\|Darb-Esfahani, S\|Lenze, D\|Heppner, F L\|Koch, A\|Sers, C\|Klauschen, F\|Anagnostopoulos, I
PMID:	26358176

2429.
Journal:	World J Gastroenterol. 2015 Sep 7;21(33):9749-57.
Title:	Annexin A10 expression in colorectal cancers with emphasis on the serrated neoplasia pathway.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Rhee, Ye-Young\|Cho, Nam-Yun\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	26361422

2430.
Journal:	PLoS One. 2015 Sep 14;10(9):e0138245.
Title:	Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.
Author:	D'Haene, Nicky\|Le Mercier, Marie\|De Neve, Nancy\|Blanchard, Oriane\|Delaunoy, Melanie\|El Housni, Hakim\|Dessars, Barbara\|Heimann, Pierre\|Remmelink, Myriam\|Demetter, Pieter\|Tejpar, Sabine\|Salmon, Isabelle
PMID:	26366557

2431.
Journal:	PLoS One. 2015 Sep 16;10(9):e0138141.
Title:	High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.
Author:	van den Broek, Evert\|Dijkstra, Maurits J J\|Krijgsman, Oscar\|Sie, Daoud\|Haan, Josien C\|Traets, Joleen J H\|van de Wiel, Mark A\|Nagtegaal, Iris D\|Punt, Cornelis J A\|Carvalho, Beatriz\|Ylstra, Bauke\|Abeln, Sanne\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	26375816

2432.
Journal:	Iran J Med Sci. 2015 Sep;40(5):454-60.
Title:	K-ras Mutation in Colorectal Cancer, A Report from Southern Iran.
Author:	Omidifar, Navid Md\|Geramizadeh, Bita Md\|Mirzai, Mitra Ms
PMID:	26379353

2433.
Journal:	Invest New Drugs. 2015 Dec;33(6):1242-7.
Title:	Safety and efficacy of the addition of simvastatin to cetuximab in previously treated KRAS mutant metastatic colorectal cancer patients.
Author:	Baas, J M\|Krens, L L\|ten Tije, A J\|Erdkamp, F\|van Wezel, T\|Morreau, H\|Gelderblom, H\|Guchelaar, H J
PMID:	26386973

2434.
Journal:	World J Gastroenterol. 2015 Sep 21;21(35):10057-61.
Title:	Stool DNA methylation assays in colorectal cancer screening.
Author:	Kadiyska, Tanya\|Nossikoff, Alexander
PMID:	26401070

2435.
Journal:	Mod Pathol. 2015 Dec;28(12):1584-93.
Title:	Serrated colorectal polyps in inflammatory bowel disease.
Author:	Ko, Huaibin M\|Harpaz, Noam\|McBride, Russell B\|Cui, Miao\|Ye, Fei\|Zhang, David\|Ullman, Thomas A\|Polydorides, Alexandros D
PMID:	26403785

2436.
Journal:	Int J Mol Sci. 2015 Sep 23;16(9):22976-88.
Title:	Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	26404261

2437.
Journal:	Cancer Biomark. 2015;15(6):843-50.
Title:	Association of CD133 polymorphisms and response to bevacizumab in patients with metastatic colorectal cancer.
Author:	Aravantinos, G\|Isaakidou, A\|Karantanos, T\|Sioziou, A\|Theodoropoulos, G E\|Pektasides, D\|Gazouli, M
PMID:	26406410

2438.
Journal:	Nature. 2015 Oct 8;526(7572):263-7.
Title:	The genomic landscape of response to EGFR blockade in colorectal cancer.
Author:	Bertotti, Andrea\|Papp, Eniko\|Jones, Sian\|Adleff, Vilmos\|Anagnostou, Valsamo\|Lupo, Barbara\|Sausen, Mark\|Phallen, Jillian\|Hruban, Carolyn A\|Tokheim, Collin\|Niknafs, Noushin\|Nesselbush, Monica\|Lytle, Karli\|Sassi, Francesco\|Cottino, Francesca\|Migliardi, Giorg
PMID:	26416732

2439.
Journal:	Oncotarget. 2015 Oct 13;6(31):30787-802.
Title:	Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy.
Author:	Alves, Sara\|Castro, Lisandra\|Fernandes, Maria Sofia\|Francisco, Rita\|Castro, Paula\|Priault, Muriel\|Chaves, Susana Rodrigues\|Moyer, Mary Pat\|Oliveira, Carla\|Seruca, Raquel\|Corte-Real, Manuela\|Sousa, Maria Joao\|Preto, Ana
PMID:	26418750

2440.
Journal:	Am J Clin Nutr. 2015 Nov;102(5):1134-41.
Title:	Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival.
Author:	Lochhead, Paul\|Nishihara, Reiko\|Qian, Zhi Rong\|Mima, Kosuke\|Cao, Yin\|Sukawa, Yasutaka\|Kim, Sun A\|Inamura, Kentaro\|Zhang, Xuehong\|Wu, Kana\|Giovannucci, Edward\|Meyerhardt, Jeffrey A\|Chan, Andrew T\|Fuchs, Charles S\|Ogino, Shuji
PMID:	26423386

2441.
Journal:	Cancer Sci. 2015 Dec;106(12):1722-9.
Title:	DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer.
Author:	Ouchi, Kota\|Takahashi, Shin\|Yamada, Yasuhide\|Tsuji, Shingo\|Tatsuno, Kenji\|Takahashi, Hidekazu\|Takahashi, Naoki\|Takahashi, Masanobu\|Shimodaira, Hideki\|Aburatani, Hiroyuki\|Ishioka, Chikashi
PMID:	26426205

2442.
Journal:	PLoS One. 2015 Oct 1;10(10):e0139727.
Title:	c-MYC Copy-Number Gain Is an Independent Prognostic Factor in Patients with Colorectal Cancer.
Author:	Lee, Kyu Sang\|Kwak, Yoonjin\|Nam, Kyung Han\|Kim, Duck-Woo\|Kang, Sung-Bum\|Choe, Gheeyoung\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	26426996

2443.
Journal:	Rom J Morphol Embryol. 2015;56(2 Suppl):671-8.
Title:	KRAS gene mutations - prognostic factor in colorectal cancer?
Author:	Dobre, Maria\|Dinu, Daniela Elena\|Panaitescu, Eugenia\|Birla, Rodica Daniela\|Iosif, Cristina Ileana\|Boeriu, Marius\|Constantinoiu, Silviu\|Ivan, Roxana Nicoleta\|Ardeleanu, Carmen Maria\|Costache, Marieta
PMID:	26429158

2444.
Journal:	Oncotarget. 2015 Oct 13;6(31):30592-603.
Title:	Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics.
Author:	Magliacane, Gilda\|Grassini, Greta\|Bartocci, Paola\|Francaviglia, Ilaria\|Dal Cin, Elena\|Barbieri, Gianluca\|Arrigoni, Gianluigi\|Pecciarini, Lorenza\|Doglioni, Claudio\|Cangi, Maria Giulia
PMID:	26435479

2445.
Journal:	Eur Rev Med Pharmacol Sci. 2015 Sep;19(18):3391-6.
Title:	Tegafur gimeracil oter combined with oxaliplatin for advanced colorectal cancer.
Author:	Yang, Z-H\|Ren, J\|Yi, L-J\|Zheng, J-H\|Wei, H
PMID:	26439033

2446.
Journal:	Oncotarget. 2015 Oct 27;6(33):34561-72.
Title:	Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Author:	Lieu, Christopher H\|Klauck, Peter J\|Henthorn, Patrick K\|Tentler, John J\|Tan, Aik-Choon\|Spreafico, Anna\|Selby, Heather M\|Britt, Blair C\|Bagby, Stacey M\|Arcaroli, John J\|Messersmith, Wells A\|Pitts, Todd M\|Eckhardt, S Gail
PMID:	26439693

2447.
Journal:	Mod Pathol. 2015 Nov;28(11):1481-91.
Title:	Assessment of a HER2 scoring system for colorectal cancer: results from a validation study.
Author:	Valtorta, Emanuele\|Martino, Cosimo\|Sartore-Bianchi, Andrea\|Penaullt-Llorca, Frederique\|Viale, Giuseppe\|Risio, Mauro\|Rugge, Massimo\|Grigioni, Walter\|Bencardino, Katia\|Lonardi, Sara\|Zagonel, Vittorina\|Leone, Francesco\|Noe, Johannes\|Ciardiello, Fortunato\|Pin
PMID:	26449765

2448.
Journal:	Curr Cancer Drug Targets. 2015;15(8):703-15.
Title:	Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice.
Author:	Maurel, Joan\|Postigo, Antonio
PMID:	26452385

2449.
Journal:	J Clin Oncol. 2015 Dec 1;33(34):4032-8.
Title:	Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.
Author:	Kopetz, Scott\|Desai, Jayesh\|Chan, Emily\|Hecht, Joel Randolph\|O'Dwyer, Peter J\|Maru, Dipen\|Morris, Van\|Janku, Filip\|Dasari, Arvind\|Chung, Woonbook\|Issa, Jean-Pierre J\|Gibbs, Peter\|James, Brian\|Powis, Garth\|Nolop, Keith B\|Bhattacharya, Suman\|Saltz, Leonard
PMID:	26460303

2450.
Journal:	Clin Cancer Res. 2015 Dec 15;21(24):5415-6.
Title:	Optimizing Anti-EGFR Therapy in Colorectal Cancer.
Author:	Salazar, Ramon\|Ciardiello, Fortunato
PMID:	26463710

2451.
Journal:	Adv Clin Exp Med. 2015 Jul-Aug;24(4):555-63.
Title:	Large Bowel Genetic Background and Inflammatory Processes in Carcinogenesis--Systematic Review.
Author:	Szylberg, Lukasz\|Janiczek, Marlena\|Popiel, Aneta\|Marszalek, Andrzej
PMID:	26469098

2452.
Journal:	Carcinogenesis. 2015 Dec;36(12):1502-10.
Title:	Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survival.
Author:	van Osch, Frits H M\|Voets, An M\|Schouten, Leo J\|Gottschalk, Ralph W H\|Simons, Colinda C J M\|van Engeland, Manon\|Lentjes, Marjolein H F M\|van den Brandt, Piet A\|Smeets, Hubert J M\|Weijenberg, Matty P
PMID:	26476438

2453.
Journal:	BMC Cancer. 2015 Oct 20;15:747.
Title:	Exploratory biomarker analysis for treatment response in KRAS wild type metastatic colorectal cancer patients who received cetuximab plus irinotecan.
Author:	Kim, Seung Tae\|Ahn, Tae Jin\|Lee, Eunjin\|Do, In-Gu\|Lee, Su Jin\|Park, Se Hoon\|Park, Joon Oh\|Park, Young Suk\|Lim, Ho Yeong\|Kang, Won Ki\|Kim, Suk Hyeong\|Lee, Jeeyun\|Kim, Hee Cheol
PMID:	26486455

2454.
Journal:	Cancer. 2015 Dec 15;121(24):4359-68.
Title:	Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinomas.
Author:	Yoshioka, Yasumasa\|Togashi, Yosuke\|Chikugo, Takaaki\|Kogita, Akihiro\|Taguri, Masataka\|Terashima, Masato\|Mizukami, Takuro\|Hayashi, Hidetoshi\|Sakai, Kazuko\|de Velasco, Marco A\|Tomida, Shuta\|Fujita, Yoshihiko\|Tokoro, Tadao\|Ito, Akihiko\|Okuno, Kiyotaka\|Nishio,
PMID:	26488212

2455.
Journal:	Gan To Kagaku Ryoho. 2015 Oct;42(10):1211-4.
Title:	[Long-Term Survival of a Patient with KRAS Mutated Colon Cancer Successfully Treated with Regorafenib].
Author:	Ohta, Ryo\|Sekikawa, Koji\|Yamazaki, Masato\|Goto, Manabu\|Narita, Kazuhiro\|Ikeda, Hironari\|Oneyama, Masataka\|Nakayama, Mikihiro\|Shimoda, Yota\|Sato, Shun\|Inoue, Takahiro
PMID:	26489551

2456.
Journal:	PLoS One. 2015 Oct 22;10(10):e0140717.
Title:	Panitumumab Use in Metastatic Colorectal Cancer and Patterns of KRAS Testing: Results from a Europe-Wide Physician Survey and Medical Records Review.
Author:	Trojan, Jorg\|Mineur, Laurent\|Tomasek, Jiri\|Rouleau, Etienne\|Fabian, Pavel\|de Maglio, Giovanna\|Garcia-Alfonso, Pilar\|Aprile, Giuseppe\|Taylor, Aliki\|Kafatos, George\|Downey, Gerald\|Terwey, Jan-Henrik\|van Krieken, J Han
PMID:	26491871

2457.
Journal:	PLoS One. 2015 Oct 23;10(10):e0138345.
Title:	Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer.
Author:	Peiris, Diluka\|Ossondo, Marlene\|Fry, Simon\|Loizidou, Marilena\|Smith-Ravin, Juliette\|Dwek, Miriam V
PMID:	26495974

2458.
Journal:	BMC Cancer. 2015 Oct 24;15:779.
Title:	Clinical detection and categorization of uncommon and concomitant mutations involving BRAF.
Author:	Zheng, Gang\|Tseng, Li-Hui\|Chen, Guoli\|Haley, Lisa\|Illei, Peter\|Gocke, Christopher D\|Eshleman, James R\|Lin, Ming-Tseh
PMID:	26498038

2459.
Journal:	BMC Cancer. 2015 Oct 27;15:808.
Title:	Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.
Author:	Lupini, Laura\|Bassi, Cristian\|Mlcochova, Jitka\|Musa, Gentian\|Russo, Marta\|Vychytilova-Faltejskova, Petra\|Svoboda, Marek\|Sabbioni, Silvia\|Nemecek, Radim\|Slaby, Ondrej\|Negrini, Massimo
PMID:	26508446

2460.
Journal:	Oncotarget. 2015 Dec 1;6(38):40815-21.
Title:	A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations.
Author:	Chen, Dawei\|Huang, Xuesong\|Cai, Jie\|Guo, Sheng\|Qian, Wubin\|Wery, Jean-Pierre\|Li, Qi-Xiang
PMID:	26512781

2461.
Journal:	Oncotarget. 2015 Dec 8;6(39):42334-44.
Title:	Mutational profiling of colorectal cancers with microsatellite instability.
Author:	Lin, Elaine I\|Tseng, Li-Hui\|Gocke, Christopher D\|Reil, Stacy\|Le, Dung T\|Azad, Nilofer S\|Eshleman, James R
PMID:	26517354

2462.
Journal:	Cytogenet Genome Res. 2015;146(4):261-7.
Title:	Colorectal Cancers with the Uncommon Findings of KRAS Mutation and Microsatellite Instability.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	26523369

2463.
Journal:	Rinsho Byori. 2015 Mar;63(3):361-8.
Title:	[Fecal Biomarker for Colorectal Cancer Diagnosis].
Author:	Koga, Yoshikatsu\|Yamazaki, Nobuyoshi\|Matsumura, Yasuhiro
PMID:	26524859

2464.
Journal:	BMC Cancer. 2015 Nov 2;15:833.
Title:	High SLFN11 expression predicts better survival for patients with KRAS exon 2 wild type colorectal cancer after treated with adjuvant oxaliplatin-based treatment.
Author:	Deng, Yanhong\|Cai, Yue\|Huang, Yan\|Yang, Zihuan\|Bai, Yang\|Liu, Yanlu\|Deng, Xiuping\|Wang, Jianping
PMID:	26525741

2465.
Journal:	Oncotarget. 2015 Nov 24;6(37):39607-13.
Title:	Molecular pathological epidemiology of colorectal cancer in Chinese patients with KRAS and BRAF mutations.
Author:	Li, Wenbin\|Qiu, Tian\|Ling, Yun\|Guo, Lei\|Li, Lin\|Ying, Jianming
PMID:	26530529

2466.
Journal:	Science. 2015 Dec 11;350(6266):1391-6.
Title:	Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Author:	Yun, Jihye\|Mullarky, Edouard\|Lu, Changyuan\|Bosch, Kaitlyn N\|Kavalier, Adam\|Rivera, Keith\|Roper, Jatin\|Chio, Iok In Christine\|Giannopoulou, Eugenia G\|Rago, Carlo\|Muley, Ashlesha\|Asara, John M\|Paik, Jihye\|Elemento, Olivier\|Chen, Zhengming\|Pappin, Darryl J\|D
PMID:	26541605

2467.
Journal:	Onco Targets Ther. 2015 Oct 22;8:3041-5.
Title:	rs712 polymorphism within let-7 microRNA-binding site might be involved in the initiation and progression of colorectal cancer in Chinese population.
Author:	Jiang, Qiang-Hua\|Peng, Hong-Xin\|Zhang, Yi\|Tian, Peng\|Xi, Zu-Lian\|Chen, Hao
PMID:	26543374

2468.
Journal:	BMC Cancer. 2015 Nov 9;15:874.
Title:	Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer.
Author:	Fornaro, Lorenzo\|Faviana, Pinuccia\|De Gregorio, Veronica\|Vivaldi, Caterina\|Paolicchi, Elisa\|Masi, Gianluca\|Loupakis, Fotios\|Sensi, Elisa\|Lupi, Cristiana\|Fontanini, Gabriella\|Wang, Yuzhuo\|Danesi, Romano\|Falcone, Alfredo\|Crea, Francesco
PMID:	26553291

2469.
Journal:	Cancer Biol Ther. 2015;16(12):1726-37.
Title:	Molecular profiling of 6,892 colorectal cancer samples suggests different possible treatment options specific to metastatic sites.
Author:	El-Deiry, Wafik S\|Vijayvergia, Namrata\|Xiu, Joanne\|Scicchitano, Angelique\|Lim, Bora\|Yee, Nelson S\|Harvey, Harold A\|Gatalica, Zoran\|Reddy, Sandeep
PMID:	26553611

2470.
Journal:	Gastroenterol Res Pract. 2015;2015:132190.
Title:	Molecular Features and Methylation Status in Early Onset (
Author:	Magnani, Giulia\|Furlan, Daniela\|Sahnane, Nora\|Reggiani Bonetti, Luca\|Domati, Federica\|Pedroni, Monica
PMID:	26557847

2471.
Journal:	PLoS One. 2015 Nov 11;10(11):e0142674.
Title:	Absolute Quantification of Endogenous Ras Isoform Abundance.
Author:	Mageean, Craig J\|Griffiths, John R\|Smith, Duncan L\|Clague, Michael J\|Prior, Ian A
PMID:	26560143

2472.
Journal:	Cancer Biol Ther. 2015;16(12):1710-9.
Title:	Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy.
Author:	Marks, Eric I\|Tan, Carlyn\|Zhang, Jun\|Zhou, Lanlan\|Yang, Zhaohai\|Scicchitano, Angelique\|El-Deiry, Wafik S
PMID:	26561209

2473.
Journal:	Cancer Manag Res. 2015 Oct 23;7:311-8.
Title:	Prospective noninterventional study on the use of panitumumab monotherapy in patients with recurrent or progressive colorectal cancer: the VECTIS study.
Author:	Lakomy, Radek\|Rogowski, Wojciech\|Piko, Bela\|Mihaylova, Zh\|Pritzova, Eva\|Kvocekova, Lucia
PMID:	26566372

2474.
Journal:	Biomed Res Int. 2015;2015:690721.
Title:	Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.
Author:	Korpetinou, Angeliki\|Papachristou, Dionysios J\|Lampropoulou, Angeliki\|Bouris, Panagiotis\|Labropoulou, Vassiliki T\|Noulas, Argyrios\|Karamanos, Nikos K\|Theocharis, Achilleas D
PMID:	26581653

2475.
Journal:	Onco Targets Ther. 2015 Nov 2;8:3185-92.
Title:	Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.
Author:	Cheng, Lei\|Xia, Zuguang\|Bian, Xinyu\|Li, Guangchao\|Hu, Jing\|Cao, Ya\|Wang, Qing\|Qian, Xiaoping
PMID:	26586952

2476.
Journal:	Rinsho Byori. 2015 Jul;63(7):870-5.
Title:	[Companion Diagnostics Sub-Section of Anatomic Pathology Department in a Mid-Sized General Hospital: Start Up and Maintenance].
Author:	Nakayama, Hirofumi\|Yasuhara, Mayumi
PMID:	26591440

2477.
Journal:	Gan To Kagaku Ryoho. 2015 Nov;42(11):1431-4.
Title:	[A Case of Complete Pathological Response in a Patient with Locally Advanced Sigmoid Colon Cancer after FOLFOX IRI Chemotherapy].
Author:	Goto, Masakazu\|Okitsu, Hiroshi\|Yuasa, Yasuhiro\|Matsuo, Yuta\|Edagawa, Hiroshi\|Tani, Ryotaro\|Mori, Osamu\|Kuramoto, Shunsuke\|Tomibayashi, Atsushi\|Yamashita, Michiko\|Fujii, Yoshiyuki
PMID:	26602406

2478.
Journal:	Onco Targets Ther. 2015 Nov 5;8:3265-76.
Title:	Assessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies.
Author:	Tang, Jie-Ting\|Wang, Zhen-Hua\|Fang, Jing-Yuan
PMID:	26604793

2479.
Journal:	J Dig Cancer Rep. 2015 Jun;3(1):5-10.
Title:	Biomarker-directed Targeted Therapy in Colorectal Cancer.
Author:	Carethers, John M
PMID:	26609516

2480.
Journal:	Curr Colorectal Cancer Rep. 2015;11(6):335-344.
Title:	Treatment Individualization in Colorectal Cancer.
Author:	van Geel, Robin M J M\|Beijnen, Jos H\|Bernards, Rene\|Schellens, Jan H M
PMID:	26617477

2481.
Journal:	PLoS One. 2015 Nov 30;10(11):e0143194.
Title:	Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype.
Author:	Maletzki, Claudia\|Huehns, Maja\|Knapp, Patrick\|Waukosin, Nancy\|Klar, Ernst\|Prall, Friedrich\|Linnebacher, Michael
PMID:	26618628

2482.
Journal:	Pol J Pathol. 2015 Sep;66(3):203-18.
Title:	Microsatellite instability in colorectal cancer: clinicopathological significance.
Author:	Setaffy, Lisa\|Langner, Cord
PMID:	26619098

2483.
Journal:	Oncol Lett. 2015 Sep;10(3):1423-1429.
Title:	Mutation of the PIK3CA gene as a prognostic factor in patients with colorectal cancer.
Author:	Stec, Rafal\|Semeniuk-Wojtas, Aleksandra\|Charkiewicz, Radoslaw\|Bodnar, Lubomir\|Korniluk, Jan\|Smoter, Marta\|Chyczewski, Lech\|Niklinski, Jacek\|Szczylik, Cezary
PMID:	26622684

2484.
Journal:	Mol Clin Oncol. 2015 Sep;3(5):1053-1057.
Title:	Cetuximab treatment for metastatic colorectal cancer with KRAS p.G13D mutations improves progression-free survival.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Osako, Masahiko\|Kawazoe, Yoshimasa\|Oba, Masaru\|Misaka, Takaharu\|Goto, Takashi\|Kamo, Hitomi\|Suenaga, Mitsukuni\|Kumekawa, Yosuke\|Ogura, Mariko\|Ozaka, Masato\|Matsusaka, Satoshi\|Chin, Keisho\|Hatake, Kiyohiko\|Mizunuma, Nobuyuki
PMID:	26623049

2485.
Journal:	Cancer Manag Res. 2015 Nov 19;7:357-60.
Title:	Durable response using regorafenib in an elderly patient with metastatic colorectal cancer: case report.
Author:	Tang, Ronald\|Kain, Tatiana\|Herman, June\|Seery, Tara
PMID:	26640390

2486.
Journal:	Ther Adv Med Oncol. 2015 May;7(3):153-69.
Title:	Therapeutic strategy in unresectable metastatic colorectal cancer: an updated review.
Author:	Chibaudel, Benoist\|Tournigand, Christophe\|Bonnetain, Franck\|Richa, Hubert\|Benetkiewicz, Magdalena\|Andre, Thierry\|de Gramont, Aimery
PMID:	26673925

2487.
Journal:	Clin Epigenetics. 2015 Dec 16;7:129.
Title:	MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy.
Author:	Garajova, Ingrid\|Funel, Niccola\|Fiorentino, Michelangelo\|Agostini, Valentina\|Ferracin, Manuela\|Negrini, Massimo\|Frassineti, Giovanni Luca\|Gavelli, Giampaolo\|Frampton, Adam Enver\|Biasco, Guido\|Giovannetti, Elisa
PMID:	26677401

2488.
Journal:	PLoS One. 2015 Dec 17;10(12):e0144708.
Title:	Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers.
Author:	Briffa, Romina\|Um, Inhwa\|Faratian, Dana\|Zhou, Ying\|Turnbull, Arran K\|Langdon, Simon P\|Harrison, David J
PMID:	26678268

2489.
Journal:	Genet Mol Res. 2015 Dec 14;14(4):16793-802.
Title:	Mutation profile of KRAS and BRAF genes in patients with colorectal cancer: association with morphological and prognostic criteria.
Author:	Samara, M\|Kapatou, K\|Ioannou, M\|Kostopoulou, Epsilon\|Papamichali, R\|Papandreou, C\|Athanasiadis, A\|Koukoulis, G
PMID:	26681025

2490.
Journal:	Sci Rep. 2015 Dec 22;5:18678.
Title:	Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases.
Author:	Zhang, Jing\|Zheng, Jianming\|Yang, Yinghong\|Lu, Junliang\|Gao, Jie\|Lu, Tao\|Sun, Jian\|Jiang, Hui\|Zhu, Yan\|Zheng, Yuhui\|Liang, Zhiyong\|Liu, Tonghua
PMID:	26691448

2491.
Journal:	Clin Epigenetics. 2015 Dec 21;7:131.
Title:	Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.
Author:	Sahnane, Nora\|Magnoli, Francesca\|Bernasconi, Barbara\|Tibiletti, Maria Grazia\|Romualdi, Chiara\|Pedroni, Monica\|Ponz de Leon, Maurizio\|Magnani, Giulia\|Reggiani-Bonetti, Luca\|Bertario, Lucio\|Signoroni, Stefano\|Capella, Carlo\|Sessa, Fausto\|Furlan, Daniela
PMID:	26697123

2492.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):645-9.
Title:	Impact of somatic mutations on patterns of metastasis in colorectal cancer.
Author:	Lipsyc, Marla\|Yaeger, Rona
PMID:	26697197

2493.
Journal:	J Gastrointest Oncol. 2015 Dec;6(6):699-708.
Title:	Hepatic resection, hepatic arterial infusion pump therapy, and genetic biomarkers in the management of hepatic metastases from colorectal cancer.
Author:	McAuliffe, John C\|Qadan, Motaz\|D'Angelica, Michael I
PMID:	26697204

2494.
Journal:	PLoS One. 2015 Dec 23;10(12):e0145698.
Title:	Single-Tubed Wild-Type Blocking Quantitative PCR Detection Assay for the Sensitive Detection of Codon 12 and 13 KRAS Mutations.
Author:	Huang, Jun-Fu\|Zeng, Dong-Zhu\|Duan, Guang-Jie\|Shi, Yan\|Deng, Guo-Hong\|Xia, Han\|Xu, Han-Qing\|Zhao, Na\|Fu, Wei-Ling\|Huang, Qing
PMID:	26701781

2495.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2015 Jun;44(6):427-30.
Title:	[Evaluation and application of methods for KRAS gene mutation detection in colorectal cancer].
Author:	Ye, Meihua\|He, Xianglei\|Lai, Maode
PMID:	26704847

2496.
Journal:	PLoS One. 2015 Dec 28;10(12):e0144825.
Title:	KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
Author:	Chattopadhyay, Nibedita\|Berger, Allison J\|Koenig, Erik\|Bannerman, Bret\|Garnsey, James\|Bernard, Hugues\|Hales, Paul\|Maldonado Lopez, Angel\|Yang, Yu\|Donelan, Jill\|Jordan, Kristen\|Tirrell, Stephen\|Stringer, Bradley\|Xia, Cindy\|Hather, Greg\|Galvin, Katherine\|Ma
PMID:	26709701

2497.
Journal:	Int J Exp Pathol. 2015 Dec;96(6):362-9.
Title:	Multiple pathways regulate Cten in colorectal cancer without a Tensin switch.
Author:	Thorpe, Hannah\|Akhlaq, Maham\|Jackson, Darryl\|Al Ghamdi, Saleh\|Storr, Sarah\|Martin, Stewart\|Ilyas, Mohammad
PMID:	26852686

2498.
Journal:	Hepatogastroenterology. 2015 May;62(139):624-8.
Title:	The Significance of Combined Measurement of p53 Antibody and other Tumor Markers for Colorectal Cancer after Curative Resection.
Author:	Kawahara, Daisuke\|Fujita, Fumihiko\|Hayashi, Hideki\|Matsuyama, Toshifumi\|Eguchi, Susumu
PMID:	26897942

2499.
Journal:	Hepatogastroenterology. 2015 Jun;62(140):876-9.
Title:	Primary Tumor Resection Offers Higher Survival Advantage in KRAS Mutant Metastatic Colorectal Cancer Patients.
Author:	Kodaz, Hilmi\|Erdogan, Bulent\|Hacibekiroglu, Ilhan\|Turkmen, Esma\|Tozkir, Hilmi\|Albayrak, Dogan\|Uzunoglu, Sernaz\|Cicin, Irfan
PMID:	26902020

2500.
Journal:	Rinsho Byori. 2015 Nov;63(11):1310-5.
Title:	[Companion Diagnostics for Solid Tumors].
Author:	Watanabe, Atsushi
PMID:	26995877

2501.
Journal:	Cell Discov. 2015 May 19;1:15005.
Title:	Modulation of tumorigenesis by the pro-inflammatory microRNA miR-301a in mouse models of lung cancer and colorectal cancer.
Author:	Ma, Xiaodong\|Yan, Fang\|Deng, Qipan\|Li, Fenge\|Lu, Zhongxin\|Liu, Mofang\|Wang, Lisheng\|Conklin, Daniel J\|McCracken, James\|Srivastava, Sanjay\|Bhatnagar, Aruni\|Li, Yong
PMID:	27462406

2502.
Journal:	Microarrays (Basel). 2015 Apr 2;4(2):188-95.
Title:	Tissue Microarray Technology for Molecular Applications: Investigation of Cross-Contamination between Tissue Samples Obtained from the Same Punching Device.
Author:	Vassella, Erik\|Galvan, Jose A\|Zlobec, Inti
PMID:	27600219

2503.
Journal:	Redox Biol. 2015 Aug;5:422.
Title:	The Development Of RRx-001, A Novel Nitric-Oxide-Mediated Epigenetically Active Anticancer Agent.
Author:	Scicinski, Jan\|Fisher, George\|Carter, Corey\|Cho-Phan, Cheryl\|Kunz, Pamela\|Ning, Shoucheng\|Knox, Susan\|Oronsky, Bryan\|Caroen, Scott\|Parker, Christopher\|Fanger, Gary\|Reid, Tony
PMID:	28162292

2504.
Journal:	RNA Dis. 2015;2(1).
Title:	KRAS Cold Turkey: Using microRNAs to target KRAS-addicted cancer.
Author:	Jones, Matthew F\|Hara, Toshifumi\|Lal, Ashish
PMID:	29367950

2505.
Journal:	Am J Clin Oncol. 2016 Jun;39(3):236-42.
Title:	Phase II Trial of Target-guided Personalized Chemotherapy in First-line Metastatic Colorectal Cancer.
Author:	Cubillo, Antonio\|Rodriguez-Pascual, Jesus\|Lopez-Rios, Fernando\|Plaza, Carlos\|Garcia, Elena\|Alvarez, Rafael\|de Vicente, Emilio\|Quijano, Yolanda\|Hernando, Ovidio\|Rubio, Carmen\|Perea, Sofia\|Sanchez, Gema\|Hidalgo, Manuel
PMID:	24517959

2506.
Journal:	Histopathology. 2016 Jan;68(2):183-90.
Title:	Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation.
Author:	Gonzalez, Raul S\|Cates, Justin M M\|Washington, Mary Kay\|Beauchamp, Robert Daniel\|Coffey, Robert J\|Shi, Chanjuan
PMID:	25913616

2507.
Journal:	Mol Carcinog. 2016 May;55(5):793-807.
Title:	UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients.
Author:	Cacciola, Nunzio Antonio\|Calabrese, Chiara\|Malapelle, Umberto\|Pellino, Gianluca\|De Stefano, Alfonso\|Sepe, Romina\|Sgariglia, Roberta\|Quintavalle, Cristina\|Federico, Antonella\|Bianco, Antonio\|Uchimura Bastos, Andre\|Milone, Marco\|Bellevicine, Claudio\|Milone,
PMID:	25917796

2508.
Journal:	Cancer Res Treat. 2016 Jan;48(1):208-15.
Title:	p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Kim, Se Hyun\|Park, Kyu Hyun\|Shin, Sang Joon\|Lee, Kang Young\|Kim, Tae Il\|Kim, Nam Kyu\|Rha, Sun Young\|Roh, Jae Kyung\|Ahn, Joong Bae
PMID:	25943321

2509.
Journal:	Gut. 2016 Aug;65(8):1296-305.
Title:	Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer.
Author:	Kloth, Michael\|Ruesseler, Vanessa\|Engel, Christoph\|Koenig, Katharina\|Peifer, Martin\|Mariotti, Erika\|Kuenstlinger, Helen\|Florin, Alexandra\|Rommerscheidt-Fuss, Ursula\|Koitzsch, Ulrike\|Wodtke, Claudia\|Ueckeroth, Frank\|Holzapfel, Stefanie\|Aretz, Stefan\|Proppi
PMID:	26001389

2510.
Journal:	Pharmacogenomics J. 2016 Jun;16(3):249-65.
Title:	Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis.
Author:	Salnikova, L E\|Kolobkov, D S
PMID:	26122021

2511.
Journal:	J Cell Physiol. 2016 Feb;231(2):459-72.
Title:	Selective beta2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis.
Author:	Chin, Chih-Chien\|Li, Jhy-Ming\|Lee, Kam-Fai\|Huang, Yun-Ching\|Wang, Kuan-Chieh\|Lai, Hsiao-Ching\|Cheng, Chih-Chung\|Kuo, Yi-Hung\|Shi, Chung-Sheng
PMID:	26189563

2512.
Journal:	Histopathology. 2016 Mar;68(4):578-87.
Title:	Serrated tubulovillous adenoma of the large intestine.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Klein, Kerenaftali\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26212352

2513.
Journal:	Clin Cancer Res. 2016 Feb 1;22(3):644-56.
Title:	Tankyrase Inhibition Blocks Wnt/beta-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
Author:	Arques, Oriol\|Chicote, Irene\|Puig, Isabel\|Tenbaum, Stephan P\|Argiles, Guillem\|Dienstmann, Rodrigo\|Fernandez, Natalia\|Caratu, Ginevra\|Matito, Judit\|Silberschmidt, Daniel\|Rodon, Jordi\|Landolfi, Stefania\|Prat, Aleix\|Espin, Eloy\|Charco, Ramon\|Nuciforo, Paolo\|
PMID:	26224873

2514.
Journal:	Clin Transl Oncol. 2016 Jan;18(1):88-92.
Title:	Colorectal cancer metastatic to the brain: analysis of prognostic factors and impact of KRAS mutations on presentation and outcome.
Author:	Nieder, C\|Hintz, M\|Grosu, A L
PMID:	26260912

2515.
Journal:	J Clin Pathol. 2016 Mar;69(3):204-8.
Title:	Correlation between DPYD gene variation and KRAS wild type status in colorectal cancer.
Author:	Kleist, Britta\|Kempa, Marcel\|Meurer, Thuja\|Poetsch, Micaela
PMID:	26281864

2516.
Journal:	Clin Cancer Res. 2016 Jan 1;22(1):230-242.
Title:	EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer.
Author:	Dunne, Philip D\|Dasgupta, Sonali\|Blayney, Jaine K\|McArt, Darragh G\|Redmond, Keara L\|Weir, Jessica-Anne\|Bradley, Conor A\|Sasazuki, Takehiko\|Shirasawa, Senji\|Wang, Tingting\|Srivastava, Supriya\|Ong, Chee Wee\|Arthur, Ken\|Salto-Tellez, Manuel\|Wilson, Richard H
PMID:	26283684

2517.
Journal:	J Cancer Res Clin Oncol. 2016 Feb;142(2):353-63.
Title:	Modal variety of microsatellite instability in human endometrial carcinomas.
Author:	Eto, Takako\|Zhao, Yan\|Maruyama, Akiko\|Miyashita, Kaname\|Yasui, Aiko\|Nakao, Seiki\|Taguchi, Kenichi\|Shimokawa, Mototsugu\|Oda, Shinya\|Saito, Toshiaki
PMID:	26298837

2518.
Journal:	Gut. 2016 Dec;65(12):1973-1980.
Title:	Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Qian, Zhi Rong\|Cao, Yin\|Sukawa, Yasutaka\|Nowak, Jonathan A\|Yang, Juhong\|Dou, Ruoxu\|Masugi, Yohei\|Song, Mingyang\|Kostic, Aleksandar D\|Giannakis, Marios\|Bullman, Susan\|Milner, Danny A\|Baba, Hideo\|Giovannucci, Edward L\|Garraway,
PMID:	26311717

2519.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38.
Title:	RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
Author:	Fang, Bingliang
PMID:	26350096

2520.
Journal:	J Clin Pathol. 2016 Jan;69(1):35-41.
Title:	Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial.
Author:	Richman, Susan D\|Adams, Richard\|Quirke, Phil\|Butler, Rachel\|Hemmings, Gemma\|Chambers, Phil\|Roberts, Helen\|James, Michelle D\|Wozniak, Sue\|Bathia, Riya\|Pugh, Cheryl\|Maughan, Timothy\|Jasani, Bharat
PMID:	26350752

2521.
Journal:	J Gastroenterol. 2016 May;51(5):447-57.
Title:	Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras.
Author:	Kawaguchi, Yasuo\|Hinoi, Takao\|Saito, Yasufumi\|Adachi, Tomohiro\|Miguchi, Masashi\|Niitsu, Hiroaki\|Sasada, Tatsunari\|Shimomura, Manabu\|Egi, Hiroyuki\|Oka, Shiro\|Tanaka, Shinji\|Chayama, Kazuaki\|Sentani, Kazuhiro\|Oue, Naohide\|Yasui, Wataru\|Ohdan, Hideki
PMID:	26361962

2522.
Journal:	Clin Cancer Res. 2016 Jan 15;22(2):405-14.
Title:	Sensitivity of KRAS-Mutant Colorectal Cancers to Combination Therapy That Cotargets MEK and CDK4/6.
Author:	Ziemke, Elizabeth K\|Dosch, Joseph S\|Maust, Joel D\|Shettigar, Amrith\|Sen, Ananda\|Welling, Theodore H\|Hardiman, Karin M\|Sebolt-Leopold, Judith S
PMID:	26369631

2523.
Journal:	Int J Cancer. 2016 Mar 1;138(5):1139-45.
Title:	Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.
Author:	de Cuba, E M V\|Snaebjornsson, P\|Heideman, D A M\|van Grieken, N C T\|Bosch, L J W\|Fijneman, R J A\|Belt, E\|Bril, H\|Stockmann, H B A C\|Hooijberg, E\|Punt, C J A\|Koopman, M\|Nagtegaal, I D\|Coupe, V H M\|Carvalho, B\|Meijer, G A
PMID:	26376292

2524.
Journal:	Cancer Immunol Res. 2016 Jan;4(1):33-40.
Title:	MicroRNA MIR21 and T Cells in Colorectal Cancer.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Nowak, Jonathan A\|Kim, Sun A\|Song, Mingyang\|Inamura, Kentaro\|Sukawa, Yasutaka\|Masuda, Atsuhiro\|Yang, Juhong\|Dou, Ruoxu\|Nosho, Katsuhiko\|Baba, Hideo\|Giovannucci, Edward L\|Bowden, Michaela\|Loda, Massimo\|Giannakis, Marios\|Bass,
PMID:	26419959

2525.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1516-27.
Title:	Combination therapy with zoledronic acid and cetuximab effectively suppresses growth of colorectal cancer cells regardless of KRAS status.
Author:	Kato, Junko\|Futamura, Manabu\|Kanematsu, Masako\|Gaowa, Siqin\|Mori, Ryutaro\|Tanahashi, Toshiyuki\|Matsuhashi, Nobuhisa\|Yoshida, Kazuhiro
PMID:	26437179

2526.
Journal:	J Clin Oncol. 2016 Jan 10;34(2):179-85.
Title:	Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Author:	Allegra, Carmen J\|Rumble, R Bryan\|Hamilton, Stanley R\|Mangu, Pamela B\|Roach, Nancy\|Hantel, Alexander\|Schilsky, Richard L
PMID:	26438111

2527.
Journal:	Tumour Biol. 2016 Mar;37(3):3571-80.
Title:	Clinical influence of cancer stem cells on residual disease after preoperative chemoradiotherapy for rectal cancer.
Author:	Yoon, Ghilsuk\|Kim, Sol-Min\|Kim, Hye Jin\|Seo, An Na
PMID:	26456957

2528.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):849-55.
Title:	Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.
Author:	Chang, Shih-Ching\|Lin, Pei-Ching\|Lin, Jen-Kou\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai
PMID:	26471487

2529.
Journal:	Int J Cancer. 2016 Mar 15;138(6):1472-81.
Title:	The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.
Author:	Renaud, Florence\|Mariette, Christophe\|Vincent, Audrey\|Wacrenier, Agnes\|Maunoury, Vincent\|Leclerc, Julie\|Coppin, Lucie\|Crepin, Michel\|Van Seuningen, Isabelle\|Leteurtre, Emmanuelle\|Buisine, Marie-Pierre
PMID:	26476272

2530.
Journal:	Clin Cancer Res. 2016 Mar 15;22(6):1489-98.
Title:	Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer.
Author:	McCleary, Nadine J\|Sato, Kaori\|Nishihara, Reiko\|Inamura, Kentaro\|Morikawa, Teppei\|Zhang, Xuehong\|Wu, Kana\|Yamauchi, Mai\|Kim, Sun A\|Sukawa, Yasutaka\|Mima, Kosuke\|Qian, Zhi Rong\|Fuchs, Charles S\|Ogino, Shuji\|Meyerhardt, Jeffrey A
PMID:	26490308

2531.
Journal:	Histopathology. 2016 May;68(6):810-8.
Title:	Traditional serrated adenoma with BRAF mutation is associated with synchronous/metachronous BRAF-mutated serrated lesions.
Author:	Tsai, Jia-Huei\|Cheng, Chien-Hsuan\|Chen, Chien-Chuan\|Lin, Yu-Lin\|Lin, Liang-In\|Chen, Mei-Ling\|Liau, Jau-Yu
PMID:	26496853

2532.
Journal:	Oncol Rep. 2016 Jan;35(1):107-16.
Title:	Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu-Jye\|Hsu, Hsi-Hsien
PMID:	26496897

2533.
Journal:	J Clin Pathol. 2016 Apr;69(4):319-25.
Title:	Frequent BRAF mutation in early-onset colorectal cancer in Taiwan: association with distinct clinicopathological and molecular features and poor clinical outcome.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Lin, Yu-Lin\|Tseng, Li-Hui\|Lin, Liang-In\|Yeh, Kun-Huei\|Jeng, Yung-Ming
PMID:	26500331

2534.
Journal:	Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):68-75.
Title:	Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors.
Author:	Levine, A Joan\|Phipps, Amanda I\|Baron, John A\|Buchanan, Daniel D\|Ahnen, Dennis J\|Cohen, Stacey A\|Lindor, Noralane M\|Newcomb, Polly A\|Rosty, Christophe\|Haile, Robert W\|Laird, Peter W\|Weisenberger, Daniel J
PMID:	26512054

2535.
Journal:	Tumour Biol. 2016 Apr;37(4):4727-34.
Title:	KRAS polymorphisms are associated with survival of CRC in Chinese population.
Author:	Dai, Qiong\|Wei, Hui Lian\|Huang, Juan\|Zhou, Tie Jun\|Chai, Li\|Yang, Zhi-Hui
PMID:	26515332

2536.
Journal:	Oncotarget. 2016 Jan 12;7(2):1311-22.
Title:	NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.
Author:	Zheng, Jianyong\|Li, Yunming\|Zhu, Shaojun\|Li, Jipeng\|Zhao, Qingchuan\|Ji, Gang\|Wang, Weizhong\|Chu, Dake
PMID:	26515606

2537.
Journal:	Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title:	Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author:	Crumley, Suzanne M\|Pepper, Kristi L\|Phan, Alexandria T\|Olsen, Randall J\|Schwartz, Mary R\|Portier, Bryce P
PMID:	26536055

2538.
Journal:	J Theor Biol. 2016 Jan 21;389:263-73.
Title:	Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer.
Author:	Sameen, Sheema\|Barbuti, Roberto\|Milazzo, Paolo\|Cerone, Antonio\|Del Re, Marzia\|Danesi, Romano
PMID:	26551156

2539.
Journal:	Virchows Arch. 2016 Apr;468(4):383-96.
Title:	RAS testing in metastatic colorectal cancer: advances in Europe.
Author:	Van Krieken, J Han J M\|Rouleau, Etienne\|Ligtenberg, Marjolijn J L\|Normanno, Nicola\|Patterson, Scott D\|Jung, Andreas
PMID:	26573425

2540.
Journal:	Ann Surg Oncol. 2016 Mar;23(3):908-17.
Title:	Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.
Author:	Hanyuda, Akiko\|Kim, Sun A\|Martinez-Fernandez, Alejandro\|Qian, Zhi Rong\|Yamauchi, Mai\|Nishihara, Reiko\|Morikawa, Teppei\|Liao, Xiaoyun\|Inamura, Kentaro\|Mima, Kosuke\|Cao, Yin\|Zhang, Xuehong\|Wu, Kana\|Chan, Andrew T\|Giovannucci, Edward L\|Meyerhardt, Jeffrey A\|
PMID:	26577117

2541.
Journal:	Ann Oncol. 2016 Feb;27(2):267-74.
Title:	Conversion to resection of liver metastases from colorectal cancer with hepatic artery infusion of combined chemotherapy and systemic cetuximab in multicenter trial OPTILIV.
Author:	Levi, F A\|Boige, V\|Hebbar, M\|Smith, D\|Lepere, C\|Focan, C\|Karaboue, A\|Guimbaud, R\|Carvalho, C\|Tumolo, S\|Innominato, P\|Ajavon, Y\|Truant, S\|Castaing, D\|De Baere, T\|Kunstlinger, F\|Bouchahda, M\|Afshar, M\|Rougier, P\|Adam, R\|Ducreux, M
PMID:	26578731

2542.
Journal:	Tumour Biol. 2016 May;37(5):5829-35.
Title:	MicroRNA-143 replenishment re-sensitizes colorectal cancer cells harboring mutant, but not wild-type, KRAS to paclitaxel treatment.
Author:	Fei, Bing-Yuan\|Wang, Xiu-Ying\|Fang, Xue-Dong
PMID:	26581910

2543.
Journal:	Cancer Chemother Pharmacol. 2016 Jan;77(1):5-18.
Title:	Oxaliplatin in the era of personalized medicine: from mechanistic studies to clinical efficacy.
Author:	Perego, Paola\|Robert, Jacques
PMID:	26589793

2544.
Journal:	Biochim Biophys Acta. 2016 Feb;1859(2):235-45.
Title:	Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.
Author:	Morgan, Rhianna K\|Batra, Harshul\|Gaerig, Vanessa C\|Hockings, Jennifer\|Brooks, Tracy A
PMID:	26597160

2545.
Journal:	J Natl Cancer Inst. 2015 Nov 23;108(4). pii: djv363.
Title:	Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status.
Author:	Inamura, Kentaro\|Song, Mingyang\|Jung, Seungyoun\|Nishihara, Reiko\|Yamauchi, Mai\|Lochhead, Paul\|Qian, Zhi Rong\|Kim, Sun A\|Mima, Kosuke\|Sukawa, Yasutaka\|Masuda, Atsuhiro\|Imamura, Yu\|Zhang, Xuehong\|Pollak, Michael N\|Mantzoros, Christos S\|Harris, Curtis C\|Giov
PMID:	26598515

2546.
Journal:	Am J Clin Nutr. 2016 Jan;103(1):192-200.
Title:	Associations of red and processed meat with survival after colorectal cancer and differences according to timing of dietary assessment.
Author:	Carr, Prudence R\|Jansen, Lina\|Walter, Viola\|Kloor, Matthias\|Roth, Wilfried\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	26607936

2547.
Journal:	Mol Diagn Ther. 2016 Feb;20(1):65-74.
Title:	KRAS Exon 2 Mutations as Prognostic Indicators in Advanced Colorectal Cancer in Clinical Practice: A Mono-Institutional Study.
Author:	Dadduzio, Vincenzo\|Basso, Michele\|Rossi, Sabrina\|Cenci, Tonia\|Capodimonti, Sara\|Strippoli, Antonia\|Orlandi, Armando\|Cerchiaro, Eleonora\|Schinzari, Giovanni\|Cassano, Alessandra\|Martini, Maurizio\|Barone, Carlo
PMID:	26610798

2548.
Journal:	Future Oncol. 2016 Jan;12(1):25-30.
Title:	Targeting BRAF aberrations in advanced colorectal carcinoma: from bench to bedside.
Author:	Abdel-Rahman, Omar
PMID:	26616508

2549.
Journal:	Virchows Arch. 2016 Mar;468(3):313-9.
Title:	Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.
Author:	Warth, Arne\|Korner, Sandrina\|Penzel, Roland\|Muley, Thomas\|Dienemann, Hendrik\|Schirmacher, Peter\|von Knebel-Doeberitz, Magnus\|Weichert, Wilko\|Kloor, Matthias
PMID:	26637197

2550.
Journal:	Cancer Discov. 2016 Feb;6(2):147-153.
Title:	Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer.
Author:	Russo, Mariangela\|Siravegna, Giulia\|Blaszkowsky, Lawrence S\|Corti, Giorgio\|Crisafulli, Giovanni\|Ahronian, Leanne G\|Mussolin, Benedetta\|Kwak, Eunice L\|Buscarino, Michela\|Lazzari, Luca\|Valtorta, Emanuele\|Truini, Mauro\|Jessop, Nicholas A\|Robinson, Hayley E\|H
PMID:	26644315

2551.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2368-76.
Title:	A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Author:	Adjei, Alex A\|Richards, Donald A\|El-Khoueiry, Anthony\|Braiteh, Fadi\|Becerra, Carlos H R\|Stephenson, Joe J Jr\|Hezel, Aram F\|Sherman, Morris\|Garbo, Lawrence\|Leffingwell, Diane P\|Iverson, Cory\|Miner, Jeffrey N\|Shen, Zancong\|Yeh, Li-Tain\|Gunawan, Sonny\|Wilson
PMID:	26644411

2552.
Journal:	Oncotarget. 2016 Jan 26;7(4):3857-72.
Title:	Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol.
Author:	Sun, Guihua\|Cheng, Ya-Wen\|Lai, Lily\|Huang, Tsui-Chin\|Wang, Jinhui\|Wu, Xiwei\|Wang, Yafan\|Huang, Yasheng\|Wang, Jinghan\|Zhang, Keqiang\|Hu, Shuya\|Yang, Ji-Rui\|Yen, Yun
PMID:	26646696

2553.
Journal:	Genes Chromosomes Cancer. 2016 Mar;55(3):268-77.
Title:	Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies.
Author:	Jesinghaus, Moritz\|Pfarr, Nicole\|Kloor, Matthias\|Endris, Volker\|Tavernar, Luca\|Muckenhuber, Alexander\|von Knebel Doeberitz, Magnus\|Penzel, Roland\|Weichert, Wilko\|Stenzinger, Albrecht
PMID:	26650777

2554.
Journal:	Oncotarget. 2016 Jan 19;7(3):3453-60.
Title:	HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer.
Author:	Takegawa, Naoki\|Yonesaka, Kimio\|Sakai, Kazuko\|Ueda, Hiroto\|Watanabe, Satomi\|Nonagase, Yoshikane\|Okuno, Tatsuya\|Takeda, Masayuki\|Maenishi, Osamu\|Tsurutani, Junji\|Satoh, Taroh\|Okamoto, Isamu\|Nishio, Kazuto\|Tamura, Takao\|Nakagawa, Kazuhiko
PMID:	26657506

2555.
Journal:	Target Oncol. 2016 Jun;11(3):363-70.
Title:	Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing.
Author:	Harle, Alexandre\|Filhine-Tresarrieu, Pierre\|Husson, Marie\|Boidot, Romain\|Rouyer, Marie\|Dubois, Cindy\|Leroux, Agnes\|Merlin, Jean-Louis
PMID:	26661077

2556.
Journal:	Tumour Biol. 2016 May;37(5):6823-30.
Title:	G12V and G12A KRAS mutations are associated with poor outcome in patients with metastatic colorectal cancer treated with bevacizumab.
Author:	Fiala, Ondrej\|Buchler, Tomas\|Mohelnikova-Duchonova, Beatrice\|Melichar, Bohuslav\|Matejka, Vit Martin\|Holubec, Lubos\|Kulhankova, Jana\|Bortlicek, Zbynek\|Bartouskova, Marie\|Liska, Vaclav\|Topolcan, Ondrej\|Sedivcova, Monika\|Finek, Jindrich
PMID:	26662311

2557.
Journal:	Invest New Drugs. 2016 Apr;34(2):168-75.
Title:	A phase I study of selumetinib (AZD6244/ARRY-142866), a MEK1/2 inhibitor, in combination with cetuximab in refractory solid tumors and KRAS mutant colorectal cancer.
Author:	Deming, Dustin A\|Cavalcante, Ludmila L\|Lubner, Sam J\|Mulkerin, Daniel L\|LoConte, Noelle K\|Eickhoff, Jens C\|Kolesar, Jill M\|Fioravanti, Suzanne\|Greten, Tim F\|Compton, Kathryn\|Doyle, Austin G\|Wilding, George\|Duffy, Austin\|Liu, Glenn
PMID:	26666244

2558.
Journal:	Tumour Biol. 2016 Jun;37(6):7295-303.
Title:	A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Author:	Bonin, Serena\|Donada, Marisa\|Bussolati, Gianni\|Nardon, Ermanno\|Annaratone, Laura\|Pichler, Martin\|Chiaravalli, Anna Maria\|Capella, Carlo\|Hoefler, Gerald\|Stanta, Giorgio
PMID:	26666825

2559.
Journal:	J Pathol. 2016 Mar;238(4):562-70.
Title:	HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer trials.
Author:	Richman, Susan D\|Southward, Katie\|Chambers, Philip\|Cross, Debra\|Barrett, Jennifer\|Hemmings, Gemma\|Taylor, Morag\|Wood, Henry\|Hutchins, Gordon\|Foster, Joseph M\|Oumie, Assa\|Spink, Karen G\|Brown, Sarah R\|Jones, Marc\|Kerr, David\|Handley, Kelly\|Gray, Richard\|Se
PMID:	26690310

2560.
Journal:	Cancer Immunol Res. 2016 Mar;4(3):204-14.
Title:	Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors.
Author:	Wang, Qiong J\|Yu, Zhiya\|Griffith, Kayla\|Hanada, Ken-ichi\|Restifo, Nicholas P\|Yang, James C
PMID:	26701267

2561.
Journal:	Cancer Med. 2016 Feb;5(2):248-55.
Title:	Targeting the PI3K signaling pathway in KRAS mutant colon cancer.
Author:	Hong, Suntaek\|Kim, SoYoung\|Kim, Hye Youn\|Kang, Myunghee\|Jang, Ho Hee\|Lee, Won-Suk
PMID:	26715098

2562.
Journal:	Cancer Med. 2016 Feb;5(2):256-64.
Title:	KRAS mutation in lung metastases from colorectal cancer: prognostic implications.
Author:	Ghidini, Michele\|Personeni, Nicola\|Bozzarelli, Silvia\|Baretti, Marina\|Basso, Gianluca\|Bianchi, Paolo\|Tronconi, Maria Chiara\|Pressiani, Tiziana\|Grizzi, Fabio\|Giordano, Laura\|Malesci, Alberto\|Alloisio, Marco\|Laghi, Luigi\|Santoro, Armando\|Rimassa, Lorenza
PMID:	26715198

2563.
Journal:	J Natl Cancer Inst. 2015 Dec 30;108(6):djv394.
Title:	Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.
Author:	Santoro, Valeria\|Jia, Ruochen\|Thompson, Hannah\|Nijhuis, Anke\|Jeffery, Rosemary\|Kiakos, Konstantinos\|Silver, Andrew R\|Hartley, John A\|Hochhauser, Daniel
PMID:	26719345

2564.
Journal:	Medicine (Baltimore). 2016 Jan;95(1):e2236.
Title:	Relationship Between 18F-Fluorodeoxyglucose Uptake and V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Mutation in Colorectal Cancer Patients: Variability Depending on C-Reactive Protein Level.
Author:	Lee, Jae-Hoon\|Kang, Jeonghyun\|Baik, Seung Hyuk\|Lee, Kang Young\|Lim, Beom Jin\|Jeon, Tae Joo\|Ryu, Young Hoon\|Sohn, Seung-Kook
PMID:	26735530

2565.
Journal:	Br J Cancer. 2016 Jan 19;114(2):199-206.
Title:	Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis.
Author:	Kim, Sun A\|Inamura, Kentaro\|Yamauchi, Mai\|Nishihara, Reiko\|Mima, Kosuke\|Sukawa, Yasutaka\|Li, Tingting\|Yasunari, Mika\|Morikawa, Teppei\|Fitzgerald, Kathryn C\|Fuchs, Charles S\|Wu, Kana\|Chan, Andrew T\|Zhang, Xuehong\|Ogino, Shuji\|Qian, Zhi Rong
PMID:	26742007

2566.
Journal:	Oncotarget. 2016 Jan 19;7(3):2159-74.
Title:	Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiation.
Author:	Le Rolle, Anne-France\|Chiu, Thang K\|Zeng, Zhaoshi\|Shia, Jinru\|Weiser, Martin R\|Paty, Philip B\|Chiu, Vi K
PMID:	26744320

2567.
Journal:	BMJ Open. 2016 Jan 8;6(1):e009532.
Title:	Validation of targeted next-generation sequencing for RAS mutation detection in FFPE colorectal cancer tissues: comparison with Sanger sequencing and ARMS-Scorpion real-time PCR.
Author:	Gao, Jie\|Wu, Huanwen\|Wang, Li\|Zhang, Hui\|Duan, Huanli\|Lu, Junliang\|Liang, Zhiyong
PMID:	26747035

2568.
Journal:	Mol Cancer Res. 2016 Mar;14(3):267-77.
Title:	Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1.
Author:	Kent, Oliver A\|Mendell, Joshua T\|Rottapel, Robert
PMID:	26747707

2569.
Journal:	Tumour Biol. 2016 Jul;37(7):8841-8.
Title:	Investigation of FIH-1 and SOCS3 expression in KRAS mutant and wild-type patients with colorectal cancer.
Author:	Vakil, Ladan\|Najafipour, Reza\|Rakhshani, Nasser\|Zamani, Farhad\|Morakabati, Arman\|Javadi, Amir
PMID:	26749281

2570.
Journal:	Gastroenterology. 2016 Apr;150(4):944-55.
Title:	Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.
Author:	Koi, Minoru\|Garcia, Melissa\|Choi, Chan\|Kim, Hyeong-Rok\|Koike, Junichi\|Hemmi, Hiromichi\|Nagasaka, Takeshi\|Okugawa, Yoshinaga\|Toiyama, Yuji\|Kitajima, Takahito\|Imaoka, Hiroki\|Kusunoki, Masato\|Chen, Yin-Hsiu\|Mukherjee, Bhramar\|Boland, C Richard\|Carethers, Joh
PMID:	26752111

2571.
Journal:	Jpn J Clin Oncol. 2016 Mar;46(3):228-33.
Title:	A short interval between bevacizumab and anti-epithelial growth factor receptor therapy interferes with efficacy of subsequent anti-EGFR therapy for refractory colorectal cancer.
Author:	Taniguchi, Hiroya\|Komori, Azusa\|Narita, Yukiya\|Kadowaki, Shigenori\|Ura, Takashi\|Andoh, Masashi\|Yatabe, Yasushi\|Komori, Koji\|Kimura, Kenichi\|Kinoshita, Takashi\|Muro, Kei
PMID:	26759349

2572.
Journal:	Gastroenterology. 2016 Apr;150(4):931-43.
Title:	Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Author:	Robles, Ana I\|Traverso, Giovanni\|Zhang, Ming\|Roberts, Nicholas J\|Khan, Mohammed A\|Joseph, Christine\|Lauwers, Gregory Y\|Selaru, Florin M\|Popoli, Maria\|Pittman, Meredith E\|Ke, Xiquan\|Hruban, Ralph H\|Meltzer, Stephen J\|Kinzler, Kenneth W\|Vogelstein, Bert\|Har
PMID:	26764183

2573.
Journal:	Crit Rev Oncol Hematol. 2016 Mar;99:150-7.
Title:	Can KRAS and BRAF mutations limit the benefit of liver resection in metastatic colorectal cancer patients? A systematic review and meta-analysis.
Author:	Passiglia, Francesco\|Bronte, Giuseppe\|Bazan, Viviana\|Galvano, Antonio\|Vincenzi, Bruno\|Russo, Antonio
PMID:	26775732

2574.
Journal:	PLoS One. 2016 Jan 20;11(1):e0144970.
Title:	Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions.
Author:	Li, Yi\|Mendiratta, Saurabh\|Ehrhardt, Kristina\|Kashyap, Neha\|White, Michael A\|Bleris, Leonidas
PMID:	26788852

2575.
Journal:	Bull Cancer. 2016 Jan;103(1):55-65.
Title:	[What future for circulating tumor DNA? Current data and prospects in colorectal, non-small cell lung and pancreatic cancers].
Author:	Pietrasz, Daniel\|Pecuchet, Nicolas\|Fabre, Elizabeth\|Blons, Helene\|Chevalier, Line\|Taly, Valerie\|Laurent-Puig, Pierre\|Bachet, Jean-Baptiste
PMID:	26790710

2576.
Journal:	World J Gastrointest Oncol. 2016 Jan 15;8(1):1-7.
Title:	Clinical efficacy and drug resistance of anti-epidermal growth factor receptor therapy in colorectal cancer.
Author:	Kocoglu, Hakan\|Velibeyoglu, Fatih Mehmet\|Karaca, Mustafa\|Tural, Deniz
PMID:	26798432

2577.
Journal:	Oncotarget. 2016 Feb 23;7(8):9188-221.
Title:	BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author:	Goulielmaki, Maria\|Koustas, Evangelos\|Moysidou, Eirini\|Vlassi, Margarita\|Sasazuki, Takehiko\|Shirasawa, Senji\|Zografos, George\|Oikonomou, Eftychia\|Pintzas, Alexander
PMID:	26802026

2578.
Journal:	World J Gastroenterol. 2016 Jan 14;22(2):815-22.
Title:	Mouse models for the discovery of colorectal cancer driver genes.
Author:	Clark, Christopher R\|Starr, Timothy K
PMID:	26811627

2579.
Journal:	World J Gastroenterol. 2016 Jan 14;22(2):887-94.
Title:	Biomarkers of skin toxicity induced by anti-epidermal growth factor receptor antibody treatment in colorectal cancer.
Author:	Kubo, Akiko\|Hashimoto, Hironobu\|Takahashi, Naoki\|Yamada, Yasuhide
PMID:	26811634

2580.
Journal:	PLoS One. 2016 Jan 26;11(1):e0147672.
Title:	Validation of a Multiplex Allele-Specific Polymerase Chain Reaction Assay for Detection of KRAS Gene Mutations in Formalin-Fixed, Paraffin-Embedded Tissues from Colorectal Cancer Patients.
Author:	Seekhuntod, Sirirat\|Thavarungkul, Paninee\|Chaichanawongsaroj, Nuntaree
PMID:	26812617

2581.
Journal:	Cancer Immunol Res. 2016 Apr;4(4):366-74.
Title:	Prospective Evaluation of Cetuximab-Mediated Antibody-Dependent Cell Cytotoxicity in Metastatic Colorectal Cancer Patients Predicts Treatment Efficacy.
Author:	Trotta, Anna Maria\|Ottaiano, Alessandro\|Romano, Carmela\|Nasti, Guglielmo\|Nappi, Anna\|De Divitiis, Chiara\|Napolitano, Maria\|Zanotta, Serena\|Casaretti, Rossana\|D'Alterio, Crescenzo\|Avallone, Antonio\|Califano, Daniela\|Iaffaioli, Rosario Vincenzo\|Scala, Stefa
PMID:	26817995

2582.
Journal:	Cancer Inform. 2016 Jan 20;15:1-13.
Title:	Correlation between Gene Variants, Signaling Pathways, and Efficacy of Chemotherapy Drugs against Colon Cancers.
Author:	Tripathi, Swarnendu\|Belkacemi, Louiza\|Cheung, Margaret S\|Bose, Rathindra N
PMID:	26819545

2583.
Journal:	Anal Chem. 2016 Mar 1;88(5):2792-8.
Title:	HistoMosaic Detecting KRAS G12V Mutation Across Colorectal Cancer Tissue Slices through in Situ PCR.
Author:	Raub, Christopher B\|Lee, Chen-Chung\|Shibata, Darryl\|Taylor, Clive\|Kartalov, Emil
PMID:	26820161

2584.
Journal:	Eur J Cancer. 2016 Mar;56:69-76.
Title:	Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent.
Author:	Haagensen, Emma J\|Thomas, Huw D\|Mudd, Clare\|Tsonou, Elpida\|Wiggins, Ceri M\|Maxwell, Ross J\|Moore, Jonathan D\|Newell, David R
PMID:	26820797

2585.
Journal:	Oncotarget. 2016 Feb 23;7(8):9309-21.
Title:	Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?
Author:	Derangere, Valentin\|Fumet, Jean David\|Boidot, Romain\|Bengrine, Leila\|Limagne, Emeric\|Chevriaux, Angelique\|Vincent, Julie\|Ladoire, Sylvain\|Apetoh, Lionel\|Rebe, Cedric\|Ghiringhelli, Francois
PMID:	26824184

2586.
Journal:	Oncotarget. 2016 Feb 23;7(8):9368-87.
Title:	miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells.
Author:	Gomes, Sofia E\|Simoes, Andre E S\|Pereira, Diane M\|Castro, Rui E\|Rodrigues, Cecilia M P\|Borralho, Pedro M
PMID:	26824186

2587.
Journal:	Dig Surg. 2016;33(2):157-63.
Title:	Right Sided Colon Cancer as a Distinct Histopathological Subtype with Reduced Prognosis.
Author:	Nitsche, Ulrich\|Stogbauer, Fabian\|Spath, Christoph\|Haller, Bernhard\|Wilhelm, Dirk\|Friess, Helmut\|Bader, Franz G
PMID:	26824772

2588.
Journal:	Tumour Biol. 2016 Aug;37(8):10209-18.
Title:	Clinical significance of fibroblast growth factor receptor 2 expression in patients with residual rectal cancer after preoperative chemoradiotherapy: relationship with KRAS or BRAF mutations and MSI status.
Author:	Yoon, Ghilsuk\|Lee, Hwayoung\|Kim, Jae-Hoon\|Hur, Keun\|Seo, An Na
PMID:	26831663

2589.
Journal:	Mol Cancer Ther. 2016 Mar;15(3):448-59.
Title:	Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.
Author:	Wang, Chun Yan\|Guo, Su Tang\|Wang, Jia Yu\|Liu, Fen\|Zhang, Yuan Yuan\|Yari, Hamed\|Yan, Xu Guang\|Jin, Lei\|Zhang, Xu Dong\|Jiang, Chen Chen
PMID:	26832792

2590.
Journal:	Int J Surg. 2016 Mar;27:147-50.
Title:	TNMF versus TNM in staging of colorectal cancer.
Author:	Ahmed Farag, Ahmed Farag\|Elbarmelgi, Mohamed Yehia\|Azim, Hamdy A\|Abozeid, Ahmed Abdelaziz\|Mashhour, Abdrabou N
PMID:	26836283

2591.
Journal:	Tumour Biol. 2016 May;37(5):5727-34.
Title:	Segmental distribution of some common molecular markers for colorectal cancer (CRC): influencing factors and potential implications.
Author:	Papagiorgis, Petros Christakis
PMID:	26842924

2592.
Journal:	Adv Anat Pathol. 2016 Mar;23(2):92-103.
Title:	The State of the Art in Colorectal Cancer Molecular Biomarker Testing.
Author:	Pillai, Raju K\|Lopategui, Jean R\|Dhall, Deepti\|Guindi, Maha\|Slavin, Thomas\|Lofton-Day, Catherine E\|Patterson, Scott D
PMID:	26849815

2593.
Journal:	Anticancer Res. 2016 Feb;36(2):677-81.
Title:	High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.
Author:	Laczmanska, Izabela\|Karpinski, Pawel\|Gil, Justyna\|Laczmanski, Lukasz\|Bebenek, Marek\|Sasiadek, Maria M
PMID:	26851024

2594.
Journal:	Genome Res. 2016 Apr;26(4):541-53.
Title:	A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1.
Author:	Hollander, Dror\|Donyo, Maya\|Atias, Nir\|Mekahel, Keren\|Melamed, Zeev\|Yannai, Sivan\|Lev-Maor, Galit\|Shilo, Asaf\|Schwartz, Schraga\|Barshack, Iris\|Sharan, Roded\|Ast, Gil
PMID:	26860615

2595.
Journal:	JAMA Oncol. 2016 Feb 11. pii: 2490542.
Title:	Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.
Author:	Seligmann, Jenny F\|Elliott, Faye\|Richman, Susan D\|Jacobs, Bart\|Hemmings, Gemma\|Brown, Sarah\|Barrett, Jennifer H\|Tejpar, Sabine\|Quirke, Philip\|Seymour, Matthew T
PMID:	26867820

2596.
Journal:	Onco Targets Ther. 2016 Jan 27;9:557-65.
Title:	Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS.
Author:	Liu, Jiang\|Hu, Jing\|Cheng, Lei\|Ren, Wei\|Yang, Mi\|Liu, Baorui\|Xie, Li\|Qian, Xiaoping
PMID:	26869800

2597.
Journal:	Iran J Pathol. 2016 Winter;11(1):71-5.
Title:	The Report of KRAS Mutation and NRAS Wild Type in a Patient with Thyroid Metastasis from Colon Cancer: a Rare Case Report.
Author:	Payandeh, Mehrdad\|Sadeghi, Masoud\|Sadeghi, Edris
PMID:	26870147

2598.
Journal:	Oncol Lett. 2016 Jan;11(1):731-734.
Title:	Expression of hepatocyte growth factor and c-Met is characteristic of alpha-fetoprotein-producing colorectal adenocarcinoma: A report of three cases.
Author:	Li, Jun\|Liu, Yue\|Xu, Jing-Hong\|Xu, Zheng-Ping\|Zheng, Shu\|Ding, Ke-Feng
PMID:	26870275

2599.
Journal:	Oncol Lett. 2016 Jan;11(1):831-836.
Title:	Appropriate use of tumour biomarkers for treatment with innovative drugs: A retrospective study.
Author:	Massa, Ilaria\|Nanni, Oriana\|Guidoboni, Massimo\|Frassineti, Giovanni Luca\|Rocca, Andrea\|Burgio, Marco Angelo\|Valmorri, Linda\|Marri, Mattia\|Piancastelli, Alessandra\|Faedi, Marina\|Leoni, Maurizio\|Tamberi, Stefano\|Altini, Mattia\|Amadori, Dino
PMID:	26870292

2600.
Journal:	Clin Gastroenterol Hepatol. 2016 May;14(5):651-8.
Title:	Molecular Biomarkers in the Personalized Treatment of Colorectal Cancer.
Author:	Sinicrope, Frank A\|Okamoto, Koichi\|Kasi, Pashtoon M\|Kawakami, Hisato
PMID:	26872400

2601.
Journal:	Cancer Genet. 2016 Apr;209(4):119-29.
Title:	Chromosomal microarray provides enhanced targetable gene aberration detection when paired with next generation sequencing panel in profiling lung and colorectal tumors.
Author:	Mukherjee, S\|Ma, Z\|Wheeler, S\|Sathanoori, M\|Coldren, C\|Prescott, J L\|Kozyr, N\|Bouzyk, M\|Correll, M\|Ho, H\|Chandra, P K\|Lennon, P A
PMID:	26880400

2602.
Journal:	Oncotarget. 2016 Mar 22;7(12):14095-111.
Title:	Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway.
Author:	Kim, Jung Ho\|Bae, Jeong Mo\|Cho, Nam-Yun\|Kang, Gyeong Hoon
PMID:	26883113

2603.
Journal:	BMC Cancer. 2016 Feb 18;16:120.
Title:	The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis.
Author:	Kim, Hae Su\|Heo, Jin Seok\|Lee, Jeeyun\|Lee, Ji Yun\|Lee, Min-Young\|Lim, Sung Hee\|Lee, Woo Yong\|Kim, Seok Hyung\|Park, Yoon Ah\|Cho, Yong Beom\|Yun, Seong Hyeon\|Kim, Seung Tae\|Park, Joon Oh\|Lim, Ho Yeong\|Choi, Yong Soo\|Kwon, Woo Il\|Kim, Hee Cheol\|Park, Young Su
PMID:	26887348

2604.
Journal:	Mod Pathol. 2016 Apr;29(4):402-15.
Title:	Clinicopathologic and prognostic associations of KRAS and BRAF mutations in small intestinal adenocarcinoma.
Author:	Jun, Sun-Young\|Kim, Misung\|Jin Gu, Mi\|Kyung Bae, Young\|Chang, Hee-Kyung\|Sun Jung, Eun\|Jang, Kee-Taek\|Kim, Jihun\|Yu, Eunsil\|Woon Eom, Dae\|Hong, Seung-Mo
PMID:	26892442

2605.
Journal:	Oncol Lett. 2016 Feb;11(2):1223-1229.
Title:	Association between the expression levels of TAZ, AXL and CTGF and clinicopathological parameters in patients with colon cancer.
Author:	Zhang, Shu-Dong\|McCrudden, Cian M\|Yuen, Hiu-Fung\|Leung, Ka Lai\|Hong, Wan-Jin\|Kwok, Hang Fai
PMID:	26893723

2606.
Journal:	Oncotarget. 2016 Mar 29;7(13):17265-74.
Title:	Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions.
Author:	Yi, Chenghao\|Huang, Yanqing\|Yu, Xing\|Li, Xiaofen\|Zheng, Shu\|Ding, Kefeng\|Xu, Jinghong
PMID:	26910894

2607.
Journal:	Breast Cancer Res Treat. 2016 Feb;156(1):33-43.
Title:	Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin.
Author:	Turturro, Sanja B\|Najor, Matthew S\|Ruby, Carl E\|Cobleigh, Melody A\|Abukhdeir, Abde M
PMID:	26915040

2608.
Journal:	Genes Chromosomes Cancer. 2016 Jun;55(6):505-21.
Title:	Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
Author:	Jesinghaus, Moritz\|Pfarr, Nicole\|Endris, Volker\|Kloor, Matthias\|Volckmar, Anna-Lena\|Brandt, Regine\|Herpel, Esther\|Muckenhuber, Alexander\|Lasitschka, Felix\|Schirmacher, Peter\|Penzel, Roland\|Weichert, Wilko\|Stenzinger, Albrecht
PMID:	26917275

2609.
Journal:	Asian Pac J Cancer Prev. 2016;17(2):539-43.
Title:	Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis.
Author:	Sasaki, Yusuke\|Hamaguchi, Tetsuya\|Yamada, Yasuhide\|Takahashi, Naoki\|Shoji, Hirokazu\|Honma, Yoshitaka\|Iwasa, Satoru\|Okita, Natsuko\|Takashima, Atsuo\|Kato, Ken\|Nagai, Yushi\|Taniguchi, Hirokazu\|Boku, Narikazu\|Ushijima, Toshikazu\|Shimada, Yasuhiro
PMID:	26925640

2610.
Journal:	Asian Pac J Cancer Prev. 2016;17(2):603-8.
Title:	Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.
Author:	Koochak, Aghigh\|Rakhshani, Nasser\|Karbalaie Niya, Mohammad Hadi\|Tameshkel, Fahimeh Safarnezhad\|Sohrabi, Masoud Reza\|Babaee, Mohammad Reza\|Rezvani, Hamid\|Bahar, Babak\|Imanzade, Farid\|Zamani, Farhad\|Khonsari, Mohammad Reza\|Ajdarkosh, Hossein\|Hemmasi, Gholam
PMID:	26925650

2611.
Journal:	BioDrugs. 2016 Apr;30(2):95-104.
Title:	Anti-EGFR Therapy for Metastatic Colorectal Cancer in the Era of Extended RAS Gene Mutational Analysis.
Author:	Kassouf, Elie\|Tabchi, Samer\|Tehfe, Mustapha
PMID:	26927802

2612.
Journal:	Clin Cancer Res. 2016 Aug 1;22(15):3831-40.
Title:	Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target.
Author:	Yakirevich, Evgeny\|Resnick, Murray B\|Mangray, Shamlal\|Wheeler, Michael\|Jackson, Cynthia L\|Lombardo, Kara A\|Lee, Jeeyun\|Kim, Kyoung-Mee\|Gill, Anthony J\|Wang, Kai\|Gowen, Kyle\|Sun, James\|Miller, Vincent A\|Stephens, Philip J\|Ali, Siraj M\|Ross, Jeffrey S\|Safra
PMID:	26933125

2613.
Journal:	Asia Pac J Clin Oncol. 2016 Sep;12(3):207-15.
Title:	Primary tumor location is an important predictive factor for wild-type KRAS metastatic colon cancer treated with cetuximab as front-line bio-therapy.
Author:	Lu, Hsueh-Ju\|Lin, Jen-Kou\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Yang, Shung-Haur\|Lan, Yuan-Tzu\|Lin, Chun-Chi\|Chang, Shih-Ching\|Teng, Hao-Wei
PMID:	26935130

2614.
Journal:	Mol Med Rep. 2016 Apr;13(4):3514-20.
Title:	Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.
Author:	Nagaoka, Tomoko\|Kitaura, Kazutaka\|Miyata, Yukinaga\|Kumagai, Kenichi\|Kaneda, Goro\|Kanazawa, Hideki\|Suzuki, Satsuki\|Hamada, Yoshiki\|Suzuki, Ryuji
PMID:	26935861

2615.
Journal:	ACS Chem Biol. 2016 May 20;11(5):1322-31.
Title:	Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer.
Author:	Bousquet, Michelle S\|Ma, Jia Jia\|Ratnayake, Ranjala\|Havre, Pamela A\|Yao, Jin\|Dang, Nam H\|Paul, Valerie J\|Carney, Thomas J\|Dang, Long H\|Luesch, Hendrik
PMID:	26938486

2616.
Journal:	J Cell Biochem. 2016 Oct;117(10):2340-5.
Title:	A Crosstalk Between K ras (Kirsten Rat Sarcoma Viral Oncogene Homologue) and Adherence Molecular Complex Leads to Disassociation of Cells-A Possible Contribution Towards Metastasis in Colorectal Cancer.
Author:	Murtaza, Bibi Nazia\|Doak, Shareen\|Morgan, Claire\|Nadeem, Muhammad Shahid\|Al-Ghanim, Khalid A\|Shakoori, Abdul Rauf
PMID:	26945839

2617.
Journal:	J Community Support Oncol. 2016 Feb;14(2):72-5.
Title:	A novel treatment approach prolonging survival in an uncommon metastatic primary bladder adenocarcinoma.
Author:	Pokuri, Venkata K\|Sule, Norbert\|Perfetto, Caroline\|Duff, Michael\|Kopp, Christopher\|Guru, Khurshid\|Shah, Dhiren\|George, Saby
PMID:	26955660

2618.
Journal:	Clin Cancer Res. 2016 Aug 1;22(15):3841-8.
Title:	MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival.
Author:	Mima, Kosuke\|Nishihara, Reiko\|Yang, Juhong\|Dou, Ruoxu\|Masugi, Yohei\|Shi, Yan\|da Silva, Annacarolina\|Cao, Yin\|Song, Mingyang\|Nowak, Jonathan\|Gu, Mancang\|Li, Wanwan\|Morikawa, Teppei\|Zhang, Xuehong\|Wu, Kana\|Baba, Hideo\|Giovannucci, Edward L\|Meyerhardt, Jeffr
PMID:	26957558

2619.
Journal:	Cell Cycle. 2016;15(4):506-18.
Title:	Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.
Author:	Lochhead, Pamela A\|Clark, Jonathan\|Wang, Lan-Zhen\|Gilmour, Lesley\|Squires, Matthew\|Gilley, Rebecca\|Foxton, Caroline\|Newell, David R\|Wedge, Stephen R\|Cook, Simon J
PMID:	26959608

2620.
Journal:	J Oncol Pract. 2016 Mar;12(3):e308-19, 259-60.
Title:	Oncologists' Selection of Genetic and Molecular Testing in the Evolving Landscape of Stage II Colorectal Cancer.
Author:	Parikh, Aparna R\|Keating, Nancy L\|Liu, Pang-Hsiang\|Gray, Stacy W\|Klabunde, Carrie N\|Kahn, Katherine L\|Haggstrom, David A\|Syngal, Sapna\|Kim, Benjamin
PMID:	26962170

2621.
Journal:	Clin Transl Gastroenterol. 2016 Mar 10;7:e151.
Title:	Tracking the Correlation Between CpG Island Methylator Phenotype and Other Molecular Features and Clinicopathological Features in Human Colorectal Cancers: A Systematic Review and Meta-Analysis.
Author:	Zong, Liang\|Abe, Masanobu\|Ji, Jiafu\|Zhu, Wei-Guo\|Yu, Duonan
PMID:	26963001

2622.
Journal:	Oncotarget. 2016 Apr 19;7(16):21825-39.
Title:	MicroRNA-543 suppresses colorectal cancer growth and metastasis by targeting KRAS, MTA1 and HMGA2.
Author:	Fan, Chuannan\|Lin, Yancheng\|Mao, Yubin\|Huang, Zhengjie\|Liu, Allan Yi\|Ma, Handong\|Yu, Donghong\|Maitikabili, Alaiyi\|Xiao, Hongjun\|Zhang, Chuankai\|Liu, Fan\|Luo, Qi\|Ouyang, Gaoliang
PMID:	26968810

2623.
Journal:	Oncotarget. 2016 Apr 19;7(16):22543-55.
Title:	Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.
Author:	Ibarrola-Villava, Maider\|Fleitas, Tania\|Llorca-Cardenosa, Marta J\|Mongort, Cristina\|Alonso, Elisa\|Navarro, Samuel\|Burgues, Octavio\|Vivancos, Ana\|Cejalvo, Juan Miguel\|Perez-Fidalgo, Jose Alejandro\|Rosello, Susana\|Ribas, Gloria\|Cervantes, Andres
PMID:	26968814

2624.
Journal:	BMC Cancer. 2016 Mar 12;16:213.
Title:	Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	26970738

2625.
Journal:	Clin Colorectal Cancer. 2016 Sep;15(3):222-7.
Title:	A Phase II Efficacy and Safety, Open-Label, Multicenter Study of Imprime PGG Injection in Combination With Cetuximab in Patients With Stage IV KRAS-Mutant Colorectal Cancer.
Author:	Segal, Neil H\|Gada, Purvi\|Senzer, Neil\|Gargano, Michele A\|Patchen, Myra L\|Saltz, Leonard B
PMID:	26975418

2626.
Journal:	Mol Cancer Ther. 2016 Jun;15(6):1217-26.
Title:	Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Author:	Togel, Lars\|Nightingale, Rebecca\|Chueh, Anderly C\|Jayachandran, Aparna\|Tran, Hoanh\|Phesse, Toby\|Wu, Rui\|Sieber, Oliver M\|Arango, Diego\|Dhillon, Amardeep S\|Dawson, Mark A\|Diez-Dacal, Beatriz\|Gahman, Timothy C\|Filippakopoulos, Panagis\|Shiau, Andrew K\|Mariad
PMID:	26983878

2627.
Journal:	J Gastroenterol. 2016 Oct;51(10):971-84.
Title:	Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications.
Author:	Belharazem, Djeda\|Magdeburg, Julia\|Berton, Ann-Kristin\|Beissbarth, Li\|Sauer, Christian\|Sticht, Carsten\|Marx, Alexander\|Hofheinz, Ralf\|Post, Stefan\|Kienle, Peter\|Strobel, Philipp
PMID:	26984550

2628.
Journal:	Mol Diagn Ther. 2016 Jun;20(3):231-40.
Title:	Novel Approach for Clinical Validation of the cobas KRAS Mutation Test in Advanced Colorectal Cancer.
Author:	Sharma, Abha\|Zhang, Guili\|Aslam, Shagufta\|Yu, Karen\|Chee, Melody\|Palma, John F
PMID:	26984642

2629.
Journal:	PLoS One. 2016 Mar 18;11(3):e0151865.
Title:	BRAF, PIK3CA, and HER2 Oncogenic Alterations According to KRAS Mutation Status in Advanced Colorectal Cancers with Distant Metastasis.
Author:	Nam, Soo Kyung\|Yun, Sumi\|Koh, Jiwon\|Kwak, Yoonjin\|Seo, An Na\|Park, Kyoung Un\|Kim, Duck-Woo\|Kang, Sung-Bum\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	26991109

2630.
Journal:	Int J Cancer. 2016 Aug 1;139(3):647-56.
Title:	Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases.
Author:	Loes, Inger Marie\|Immervoll, Heike\|Sorbye, Halfdan\|Angelsen, Jon-Helge\|Horn, Arild\|Knappskog, Stian\|Lonning, Per Eystein
PMID:	26991344

2631.
Journal:	Cancer Sci. 2016 Jun;107(6):820-7.
Title:	TP53 mutation at early stage of colorectal cancer progression from two types of laterally spreading tumors.
Author:	Sakai, Eiji\|Fukuyo, Masaki\|Matsusaka, Keisuke\|Ohata, Ken\|Doi, Noriteru\|Takane, Kiyoko\|Matsuhashi, Nobuyuki\|Fukushima, Junichi\|Nakajima, Atsushi\|Kaneda, Atsushi
PMID:	26991699

2632.
Journal:	Hum Pathol. 2016 Apr;50:183-6.
Title:	Early signet ring cell carcinoma arising from colonic adenoma: the molecular profiling supports the adenoma-carcinoma sequence.
Author:	Bellan, Alberto\|Cappellesso, Rocco\|Lo Mele, Marcello\|Peraro, Laura\|Balsamo, Laura\|Lanza, Cristiano\|Fassan, Matteo\|Rugge, Massimo
PMID:	26997454

2633.
Journal:	Cancer. 2016 Jun 1;122(11):1689-96.
Title:	Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/beta-catenin signaling pathway mutations.
Author:	Yuan, Wei\|Zhang, Zhou\|Dai, Binghua\|Wei, Qing\|Liu, Jinjin\|Liu, Yuzhen\|Liu, Yun\|He, Lin\|Zhou, Daizhan
PMID:	26998897

2634.
Journal:	Hum Pathol. 2016 Jul;53:91-6.
Title:	Medullary carcinoma in the colorectum: a systematic review and meta-analysis.
Author:	Pyo, Jung-Soo\|Sohn, Jin Hee\|Kang, Guhyun
PMID:	27001432

2635.
Journal:	Ann Oncol. 2016 Jun;27(6):1055-61.
Title:	Cetuximab continuation after first progression in metastatic colorectal cancer (CAPRI-GOIM): a randomized phase II trial of FOLFOX plus cetuximab versus FOLFOX.
Author:	Ciardiello, F\|Normanno, N\|Martinelli, E\|Troiani, T\|Pisconti, S\|Cardone, C\|Nappi, A\|Bordonaro, A R\|Rachiglio, M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vit
PMID:	27002107

2636.
Journal:	Cureus. 2016 Feb 3;8(2):e478.
Title:	KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer.
Author:	Loaiza-Bonilla, Arturo\|Jensen, Christopher E\|Shroff, Stuti\|Furth, Emma\|Bonilla-Reyes, Paula A\|Deik, Andres F\|Morrissette, Jennifer
PMID:	27004155

2637.
Journal:	Int J Cancer. 2016 Aug 15;139(4):803-11.
Title:	RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Suenaga, Mitsukuni\|Matsusaka, Satoshi\|Konishi, Tsuyoshi\|Akiyoshi, Takashi\|Fujimoto, Yoshiya\|Nagayama, Satoshi\|Fukunaga, Yosuke\|Ueno, Masashi\|Mise, Yoshihiro\|Ishizawa, Takeaki\|Inoue, Yosuke\|Takahashi, Yu\|Saiura, Akio\|Uehara, H
PMID:	27004837

2638.
Journal:	Oncotarget. 2016 Apr 19;7(16):22687-99.
Title:	DDX3 enhances oncogenic KRASinduced tumor invasion in colorectal cancer via the betacatenin/ZEB1 axis.
Author:	Wu, De-Wei\|Lin, Po-Lin\|Cheng, Ya-Wen\|Huang, Chi-Chou\|Wang, Lee\|Lee, Huei
PMID:	27007150

2639.
Journal:	Free Radic Biol Med. 2016 Jun;95:200-8.
Title:	L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells.
Author:	Jung, Soo-A\|Lee, Dae-Hee\|Moon, Jai-Hee\|Hong, Seung-Woo\|Shin, Jae-Sik\|Hwang, Ih Yeon\|Shin, Yu Jin\|Kim, Jeong Hee\|Gong, Eun-Yeung\|Kim, Seung-Mi\|Lee, Eun Young\|Lee, Seul\|Kim, Jeong Eun\|Kim, Kyu-Pyo\|Hong, Yong Sang\|Lee, Jung Shin\|Jin, Dong-Hoon\|Kim, TaeWon\|Le
PMID:	27012422

2640.
Journal:	Crit Rev Oncol Hematol. 2016 May;101:151-7.
Title:	Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.
Author:	Temraz, Sally\|Mukherji, Deborah\|Shamseddine, Ali
PMID:	27017409

2641.
Journal:	Ann Surg Oncol. 2016 Aug;23(8):2548-55.
Title:	KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy.
Author:	Chow, Oliver S\|Kuk, Deborah\|Keskin, Metin\|Smith, J Joshua\|Camacho, Niedzica\|Pelossof, Raphael\|Chen, Chin-Tung\|Chen, Zhenbin\|Avila, Karin\|Weiser, Martin R\|Berger, Michael F\|Patil, Sujata\|Bergsland, Emily\|Garcia-Aguilar, Julio
PMID:	27020587

2642.
Journal:	Int J Colorectal Dis. 2016 May;31(5):973-982.
Title:	Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.
Author:	Lennerz, Jochen K\|van der Sloot, Kimberley W J\|Le, Long Phi\|Batten, Julie M\|Han, Jae Young\|Fan, Kenneth C\|Siegel, Corey A\|Srivastava, Amitabh\|Park, Do Youn\|Chen, Jey-Hsin\|Sands, Bruce E\|Korzenik, Joshua R\|Odze, Robert D\|Dias-Santagata, Dora\|Borger, Darrel
PMID:	27026089

2643.
Journal:	Pathol Oncol Res. 2016 Oct;22(4):707-14.
Title:	The Prognostic Influence of BRAF Mutation and other Molecular, Clinical and Laboratory Parameters in Stage IV Colorectal Cancer.
Author:	Karadima, Maria L\|Saetta, Angelica A\|Chatziandreou, Ilenia\|Lazaris, Andreas C\|Patsouris, Efstratios\|Tsavaris, Nikolaos
PMID:	27033063

2644.
Journal:	J Gastrointest Oncol. 2016 Apr;7(Suppl 1):S11-20.
Title:	Molecular testing to optimize therapeutic decision making in advanced colorectal cancer.
Author:	Semrad, Thomas J\|Kim, Edward J
PMID:	27034809

2645.
Journal:	Hum Pathol. 2016 Aug;54:37-46.
Title:	Localization of active, dually phosphorylated extracellular signal-regulated kinase 1 and 2 in colorectal cancer with or without activating BRAF and KRAS mutations.
Author:	Holck, Susanne\|Bonde, Jesper\|Pedersen, Helle\|Petersen, Anja Alex\|Chaube, Amita\|Nielsen, Hans Jorgen\|Larsson, Lars-Inge
PMID:	27036313

2646.
Journal:	BMC Cancer. 2016 Apr 1;16:260.
Title:	Systematic review: brain metastases from colorectal cancer--Incidence and patient characteristics.
Author:	Christensen, Troels Dreier\|Spindler, Karen-Lise Garm\|Palshof, Jesper Andreas\|Nielsen, Dorte Lisbet
PMID:	27037031

2647.
Journal:	Asian Pac J Cancer Prev. 2016;17(3):1175-9.
Title:	Distribution of KRAS and BRAF Mutations in Metastatic Colorectal Cancers in Turkish Patients.
Author:	Gorukmez, Orhan\|Yakut, Tahsin\|Gorukmez, Ozlem\|Sag, Sebnem Ozemri\|Karkucak, Mutlu\|Kanat, Ozkan
PMID:	27039744

2648.
Journal:	Int J Mol Sci. 2016 Apr 1;17(4):484.
Title:	KRAS G12V Mutation Detection by Droplet Digital PCR in Circulating Cell-Free DNA of Colorectal Cancer Patients.
Author:	Olmedillas Lopez, Susana\|Garcia-Olmo, Dolores C\|Garcia-Arranz, Mariano\|Guadalajara, Hector\|Pastor, Carlos\|Garcia-Olmo, Damian
PMID:	27043547

2649.
Journal:	Front Cell Infect Microbiol. 2016 Mar 23;6:34.
Title:	Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis.
Author:	Graillot, Vanessa\|Dormoy, Inge\|Dupuy, Jacques\|Shay, Jerry W\|Huc, Laurence\|Mirey, Gladys\|Vignard, Julien
PMID:	27047802

2650.
Journal:	World J Gastroenterol. 2016 Apr 7;22(13):3516-30.
Title:	Serrated colorectal cancer: Molecular classification, prognosis, and response to chemotherapy.
Author:	Murcia, Oscar\|Juarez, Miriam\|Hernandez-Illan, Eva\|Egoavil, Cecilia\|Giner-Calabuig, Mar\|Rodriguez-Soler, Maria\|Jover, Rodrigo
PMID:	27053844

2651.
Journal:	Cancer Biomark. 2016 Mar 4;16(4):513-21.
Title:	KRAS mutation associated with CD44/CD166 immunoexpression as predictors of worse outcome in metastatic colon cancer.
Author:	Ribeiro, Karen Bento\|da Silva Zanetti, Juliana\|Ribeiro-Silva, Alfredo\|Rapatoni, Liane\|de Oliveira, Harley Francisco\|da Cunha Tirapelli, Daniela Pretti\|Garcia, Sergio Britto\|Feres, Omar\|da Rocha, Jose Joaquim Ribeiro\|Peria, Fernanda Maris
PMID:	27062566

2652.
Journal:	PLoS One. 2016 Apr 11;11(4):e0153278.
Title:	Heterogeneity of KRAS Mutation Status in Rectal Cancer.
Author:	Jo, Peter\|Konig, Alexander\|Schirmer, Markus\|Kitz, Julia\|Conradi, Lena-Christin\|Azizian, Azadeh\|Bernhardt, Markus\|Wolff, Hendrik A\|Grade, Marian\|Ghadimi, Michael\|Strobel, Philipp\|Schildhaus, Hans-Ulrich\|Gaedcke, Jochen
PMID:	27064574

2653.
Journal:	Gan To Kagaku Ryoho. 2016 Feb;43(2):229-33.
Title:	[Relationship between the Incidence of Hypomagnesemia and Acneiform Rash and the Therapeutic Effect of Anti-EGFR Monoclonal Antibody in Patients with Metastatic Colorectal Cancer].
Author:	Fujii, Hironori\|Iihara, Hirotoshi\|Ishihara, Masashi\|Matsuhashi, Nobuhisa\|Takahashi, Takao\|Yoshida, Kazuhiro\|Itoh, Yoshinori
PMID:	27067688

2654.
Journal:	Gan To Kagaku Ryoho. 2016 Mar;43(3):377-9.
Title:	[A Case of an Unresectable Locally Advanced Rectal Cancer with Surrounding Organ Invasion Successfully Resected after Chemotherapy with mFOLFOX6 plus Cetuximab].
Author:	Takagi, Hironori\|Ariake, Kyohei\|Takemura, Shinichi\|Doi, Takashi
PMID:	27067860

2655.
Journal:	Anticancer Res. 2016 Apr;36(4):1571-9.
Title:	Rapid and Specific Screening Assay for KRAS Oncogene Mutation by a Novel Gene Amplification Method.
Author:	Kumasaka, Akira\|Matsumoto, Naoyuki\|Mukae, Shotaro\|Kitano, Taiichi\|Noguchi, Hiroyasu\|Ohki, Hidero\|Komiyama, Kazuo\|Ando, Tomohiro
PMID:	27069133

2656.
Journal:	J Cancer Res Ther. 2016 Jan-Mar;12(1):96-102.
Title:	The association of clinicopathological features and survival in colorectal cancer patients with kras mutation status.
Author:	Akman, Tulay\|Oztop, Ilhan\|Baskin, Yasemin\|Unek, Ilkay Tugba\|Demir, Necla\|Ellidokuz, Hulya\|Yilmaz, Ahmet Ugur
PMID:	27072218

2657.
Journal:	Sci Rep. 2016 Apr 14;6:24310.
Title:	Prognostic impact of mutation profiling in patients with stage II and III colon cancer.
Author:	Shen, Yinchen\|Han, Xiaohong\|Wang, Jianfei\|Wang, Shuai\|Yang, Hongying\|Lu, Shih-Hsin\|Shi, Yuankai
PMID:	27074743

2658.
Journal:	Medicine (Baltimore). 2016 Apr;95(15):e3321.
Title:	MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers.
Author:	Choi, Yong Won\|Song, Young Soo\|Lee, Hyunwoo\|Yi, Kijong\|Kim, Young-Bae\|Suh, Kwang Wook\|Lee, Dakeun
PMID:	27082577

2659.
Journal:	Qual Life Res. 2016 Oct;25(10):2645-2656.
Title:	Skin toxicity and quality of life during treatment with panitumumab for RAS wild-type metastatic colorectal carcinoma: results from three randomised clinical trials.
Author:	Koukakis, Reija\|Gatta, Francesca\|Hechmati, Guy\|Siena, Salvatore
PMID:	27083443

2660.
Journal:	Pol Przegl Chir. 2016 Jan 1;88(1):15-9.
Title:	K-ras gene mutation as an early prognostic marker of colon cancer.
Author:	Szpon, Lukasz\|Stal, Aleksander\|Zawadzki, Marcin\|Lis-Nawara, Anna\|Kielan, Wojciech\|Grzebieniak, Zygmunt
PMID:	27096769

2661.
Journal:	PLoS One. 2016 Apr 21;11(4):e0154038.
Title:	Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.
Author:	Froyen, Guy\|Broekmans, An\|Hillen, Femke\|Pat, Karin\|Achten, Ruth\|Mebis, Jeroen\|Rummens, Jean-Luc\|Willemse, Johan\|Maes, Brigitte
PMID:	27101000

2662.
Journal:	Inflamm Bowel Dis. 2016 Jul;22(7):1559-67.
Title:	DNA Methylation and Mutation of Small Colonic Neoplasms in Ulcerative Colitis and Crohn's Colitis: Implications for Surveillance.
Author:	Johnson, David H\|Taylor, William R\|Aboelsoud, Mohammed M\|Foote, Patrick H\|Yab, Tracy C\|Cao, Xiaoming\|Smyrk, Thomas C\|Loftus, Edward V Jr\|Mahoney, Douglas W\|Ahlquist, David A\|Kisiel, John B
PMID:	27104828

2663.
Journal:	Lancet Oncol. 2016 Jun;17(6):738-746.
Title:	Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial.
Author:	Sartore-Bianchi, Andrea\|Trusolino, Livio\|Martino, Cosimo\|Bencardino, Katia\|Lonardi, Sara\|Bergamo, Francesca\|Zagonel, Vittorina\|Leone, Francesco\|Depetris, Ilaria\|Martinelli, Erika\|Troiani, Teresa\|Ciardiello, Fortunato\|Racca, Patrizia\|Bertotti, Andrea\|Sirav
PMID:	27108243

2664.
Journal:	Cancer Sci. 2016 Jul;107(7):936-43.
Title:	Utility of KRAS mutation detection using circulating cell-free DNA from patients with colorectal cancer.
Author:	Yamada, Takeshi\|Iwai, Takuma\|Takahashi, Goro\|Kan, Hayato\|Koizumi, Michihiro\|Matsuda, Akihisa\|Shinji, Seiichi\|Yamagishi, Aya\|Yokoyama, Yasuyuki\|Tatsuguchi, Atsushi\|Kawagoe, Tatsuro\|Kitano, Shiro\|Nakayama, Masato\|Matsumoto, Satoshi\|Uchida, Eiji
PMID:	27116474

2665.
Journal:	Cell Rep. 2016 May 3;15(5):978-987.
Title:	KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes.
Author:	McKenzie, Andrew J\|Hoshino, Daisuke\|Hong, Nan Hyung\|Cha, Diana J\|Franklin, Jeffrey L\|Coffey, Robert J\|Patton, James G\|Weaver, Alissa M
PMID:	27117408

2666.
Journal:	Clin Colorectal Cancer. 2016 Dec;15(4):337-344.e2.
Title:	A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma.
Author:	Bowles, Daniel W\|Kochenderfer, Mark\|Cohn, Allen\|Sideris, Lucas\|Nguyen, Nghia\|Cline-Burkhardt, Vivian\|Schnadig, Ian\|Choi, Minsig\|Nabell, Lisle\|Chaudhry, Arvind\|Ruxer, Robert\|Ucar, Antonio\|Hausman, Diana\|Walker, Luke\|Spira, Alexander\|Jimeno, Antonio
PMID:	27118441

2667.
Journal:	Oncotarget. 2016 Aug 2;7(31):49042-49064.
Title:	Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype.
Author:	Deevi, Ravi K\|McClements, Jane\|McCloskey, Karen D\|Fatehullah, Aliya\|Tkocz, Dorota\|Javadi, Arman\|Higginson, Robyn\|Marsh Durban, Victoria\|Jansen, Marnix\|Clarke, Alan\|Loughrey, Maurice B\|Campbell, Frederick C
PMID:	27119498

2668.
Journal:	PLoS One. 2016 Apr 28;11(4):e0154326.
Title:	Biobanking of Fresh-Frozen Human Adenocarcinomatous and Normal Colon Tissues: Which Parameters Influence RNA Quality?
Author:	Galissier, Thibaut\|Schneider, Christophe\|Nasri, Saviz\|Kanagaratnam, Lukshe\|Fichel, Caroline\|Coquelet, Christelle\|Diebold, Marie-Daniele\|Kianmanesh, Reza\|Bellon, Georges\|Dedieu, Stephane\|Marchal Bressenot, Aude\|Boulagnon-Rombi, Camille
PMID:	27124490

2669.
Journal:	Int J Biol Macromol. 2016 Aug;89:228-37.
Title:	Interaction of KRAS G-quadruplex with natural polyphenols: A spectroscopic analysis with molecular modeling.
Author:	Pattanayak, Rudradip\|Basak, Pijush\|Sen, Srikanta\|Bhattacharyya, Maitree
PMID:	27130653

2670.
Journal:	Ann Oncol. 2016 Apr;27 Suppl 1:i53-i57.
Title:	Mucinous epithelial ovarian carcinoma.
Author:	Perren, T J
PMID:	27141073

2671.
Journal:	Clin Cancer Res. 2016 Oct 1;22(19):4923-4933.
Title:	BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.
Author:	Bartolini, Alice\|Cardaci, Sabrina\|Lamba, Simona\|Oddo, Daniele\|Marchio, Caterina\|Cassoni, Paola\|Amoreo, Carla Azzurra\|Corti, Giorgio\|Testori, Alessandro\|Bussolino, Federico\|Pasqualini, Renata\|Arap, Wadih\|Cora, Davide\|Di Nicolantonio, Federica\|Marchio, Sere
PMID:	27143691

2672.
Journal:	Cancer Biol Med. 2016 Mar;13(1):136-41.
Title:	Second-line panitumumab as a triweekly dose for patients with wild-type KRAS exon 2 metastatic colorectal cancer: a single-institution experience.
Author:	Daoud, Mohamed A\|Aboelnaga, Engy M\|Mohamed, Wael M
PMID:	27144068

2673.
Journal:	Oncotarget. 2016 Jun 7;7(23):34322-40.
Title:	MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism.
Author:	Pereira, Diane M\|Simoes, Andre E S\|Gomes, Sofia E\|Castro, Rui E\|Carvalho, Tania\|Rodrigues, Cecilia M P\|Borralho, Pedro M
PMID:	27144434

2674.
Journal:	Br J Radiol. 2016 Jul;89(1063):20160212.
Title:	(18)F-FDG PET/CT imaging in rectal cancer: relationship with the RAS mutational status.
Author:	Lovinfosse, Pierre\|Koopmansch, Benjamin\|Lambert, Frederic\|Jodogne, Sebastien\|Kustermans, Gaelle\|Hatt, Mathieu\|Visvikis, Dimitris\|Seidel, Laurence\|Polus, Marc\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	27146067

2675.
Journal:	J Transl Med. 2016 May 4;14(1):118.
Title:	Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.
Author:	Dallol, Ashraf\|Buhmeida, Abdelbaset\|Al-Ahwal, Mahmoud Shaheen\|Al-Maghrabi, Jaudah\|Bajouh, Osama\|Al-Khayyat, Shadi\|Alam, Rania\|Abusanad, Atlal\|Turki, Rola\|Elaimi, Aisha\|Alhadrami, Hani A\|Abuzenadah, Mohammed\|Banni, Huda\|Al-Qahtani, Mohammed H\|Abuzenadah, A
PMID:	27146902

2676.
Journal:	Acta Dermatovenerol Croat. 2016 Apr;24(1):70-2.
Title:	Adverse Reaction to Cetuximab, an Epidermal Growth Factor Receptor Inhibitor.
Author:	Stulhofer Buzina, Daska\|Martinac, Ivana\|Ledic Drvar, Daniela\|Ceovic, Romana\|Bilic, Ivan\|Marinovic, Branka
PMID:	27149134

2677.
Journal:	J Transl Med. 2016 May 6;14(1):125.
Title:	GNAS mutations as prognostic biomarker in patients with relapsed peritoneal pseudomyxoma receiving metronomic capecitabine and bevacizumab: a clinical and translational study.
Author:	Pietrantonio, Filippo\|Berenato, Rosa\|Maggi, Claudia\|Caporale, Marta\|Milione, Massimo\|Perrone, Federica\|Tamborini, Elena\|Baratti, Dario\|Kusamura, Shigeki\|Mariani, Luigi\|Niger, Monica\|Mennitto, Alessia\|Gloghini, Annunziata\|Bossi, Ilaria\|Settanni, Giulio\|Bus
PMID:	27154293

2678.
Journal:	J Mol Diagn. 2016 Jul;18(4):471-9.
Title:	Driver Gene Mutations in Stools of Colorectal Carcinoma Patients Detected by Targeted Next-Generation Sequencing.
Author:	Armengol, Gemma\|Sarhadi, Virinder K\|Ghanbari, Reza\|Doghaei-Moghaddam, Masoud\|Ansari, Reza\|Sotoudeh, Masoud\|Puolakkainen, Pauli\|Kokkola, Arto\|Malekzadeh, Reza\|Knuutila, Sakari
PMID:	27155048

2679.
Journal:	J Transl Med. 2016 May 10;14(1):128.
Title:	Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer.
Author:	Larsson, Anna H\|Lehn, Sophie\|Wangefjord, Sakarias\|Karnevi, Emelie\|Kuteeva, Eugenia\|Sundstrom, Magnus\|Nodin, Bjorn\|Uhlen, Mathias\|Eberhard, Jakob\|Birgisson, Helgi\|Jirstrom, Karin
PMID:	27160084

2680.
Journal:	Cancer Discov. 2016 Jul;6(7):OF5.
Title:	Colorectal Cancer Yields to Dual HER2 Blockade.
Author:
PMID:	27165728

2681.
Journal:	Oncotarget. 2016 Jun 28;7(26):39595-39608.
Title:	Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models.
Author:	Lee, Michael S\|Helms, Timothy L\|Feng, Ningping\|Gay, Jason\|Chang, Qing Edward\|Tian, Feng\|Wu, Ji Y\|Toniatti, Carlo\|Heffernan, Timothy P\|Powis, Garth\|Kwong, Lawrence N\|Kopetz, Scott
PMID:	27167191

2682.
Journal:	Oncotarget. 2016 Jun 14;7(24):36474-36488.
Title:	Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.
Author:	Suraweera, Nirosha\|Mouradov, Dmitri\|Li, Shan\|Jorissen, Robert N\|Hampson, Debbie\|Ghosh, Anil\|Sengupta, Neel\|Thaha, Mohamed\|Ahmed, Shafi\|Kirwan, Michael\|Aleva, Floor\|Propper, David\|Feakins, Roger M\|Vulliamy, Tom\|Elwood, Ngaire J\|Tian, Pei\|Ward, Robyn L\|Hawk
PMID:	27167335

2683.
Journal:	Eur Urol. 2016 Nov;70(5):771-775.
Title:	Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition.
Author:	Collazo-Lorduy, Ana\|Castillo-Martin, Mireia\|Wang, Li\|Patel, Vaibhav\|Iyer, Gopa\|Jordan, Emmet\|Al-Ahmadie, Hikmat\|Leonard, Issa\|Oh, William K\|Zhu, Jun\|McBride, Russell B\|Cordon-Cardo, Carlos\|Solit, David B\|Sfakianos, John P\|Galsky, Matthew D
PMID:	27178450

2684.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2435-44.
Title:	Fc-gamma Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.
Author:	Liu, Geoffrey\|Tu, Dongsheng\|Lewis, Marcia\|Cheng, Dangxiao\|Sullivan, Leslie A\|Chen, Zhuo\|Morgen, Eric\|Simes, John\|Price, Timothy J\|Tebbutt, Niall C\|Shapiro, Jeremy D\|Jeffery, G Mark\|Mellor, J Daniel\|Mikeska, Thomas\|Virk, Shakeel\|Shepherd, Lois E\|Jonker, De
PMID:	27179112

2685.
Journal:	Pol J Pathol. 2016 Mar;67(1):13-8.
Title:	Concordance of KRAS mutation status between luminal and peripheral regions of primary colorectal cancer. A laser-capture microdissection-based study.
Author:	Lewandowska, M\|Hybiak, J\|Domagala, W
PMID:	27179269

2686.
Journal:	Pathol Res Pract. 2016 Jul;212(7):598-603.
Title:	Locally advanced rectal cancers with simultaneous occurrence of KRAS mutation and high VEGF expression show invasive characteristics.
Author:	Krajnovic, Milena\|Markovic, Bojana\|Knezevic-Usaj, Slavica\|Nikolic, Ivan\|Stanojevic, Maja\|Nikolic, Valentina\|Siljic, Marina\|Jovanovic Cupic, Snezana\|Dimitrijevic, Bogomir
PMID:	27184911

2687.
Journal:	Cancers (Basel). 2016 May 14;8(5). pii: cancers8050049.
Title:	In Hyperthermia Increased ERK and WNT Signaling Suppress Colorectal Cancer Cell Growth.
Author:	Bordonaro, Michael\|Shirasawa, Senji\|Lazarova, Darina L
PMID:	27187477

2688.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1334-42.
Title:	Clinical impact and network of determinants of tumour necrosis in colorectal cancer.
Author:	Vayrynen, Sara A\|Vayrynen, Juha P\|Klintrup, Kai\|Makela, Jyrki\|Karttunen, Tuomo J\|Tuomisto, Anne\|Makinen, Markus J
PMID:	27195424

2689.
Journal:	Mod Pathol. 2016 Sep;29(9):1104-12.
Title:	PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes.
Author:	Rosenbaum, Matthew W\|Bledsoe, Jacob R\|Morales-Oyarvide, Vicente\|Huynh, Tiffany G\|Mino-Kenudson, Mari
PMID:	27198569

2690.
Journal:	Mod Pathol. 2016 Aug;29(8):915-27.
Title:	Colorectal tumor molecular phenotype and miRNA: expression profiles and prognosis.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Mullany, Lila E\|Wolff, Erica\|Hoffman, Michael D\|Pellatt, Daniel F\|Stevens, John R\|Wolff, Roger K
PMID:	27198570

2691.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

2692.
Journal:	Cancer Prev Res (Phila). 2016 Jun;9(6):417-27.
Title:	Genomic Landscape of Colorectal Mucosa and Adenomas.
Author:	Borras, Ester\|San Lucas, F Anthony\|Chang, Kyle\|Zhou, Ruoji\|Masand, Gita\|Fowler, Jerry\|Mork, Maureen E\|You, Y Nancy\|Taggart, Melissa W\|McAllister, Florencia\|Jones, David A\|Davies, Gareth E\|Edelmann, Winfried\|Ehli, Erik A\|Lynch, Patrick M\|Hawk, Ernest T\|Cap
PMID:	27221540

2693.
Journal:	BMC Cancer. 2016 May 24;16:327.
Title:	Primary tumor site is a useful predictor of cetuximab efficacy in the third-line or salvage treatment of KRAS wild-type (exon 2 non-mutant) metastatic colorectal cancer: a nationwide cohort study.
Author:	Chen, Kuo-Hsing\|Shao, Yu-Yun\|Chen, Ho-Min\|Lin, Yu-Lin\|Lin, Zhong-Zhe\|Lai, Mei-Shu\|Cheng, Ann-Lii\|Yeh, Kun-Huei
PMID:	27221731

2694.
Journal:	Asian Pac J Cancer Prev. 2016;17(4):1729-32.
Title:	Correlation between RAS Test Results and Prognosis of Metastatic Colorectal Cancer Patients: a Report from Western Iran.
Author:	Payandeh, Mehrdad\|Shazad, Babak\|Sadeghi, Masoud\|Shahbazi, Maryam
PMID:	27221845

2695.
Journal:	World J Gastroenterol. 2016 May 28;22(20):4936-45.
Title:	Longitudinal molecular characterization of endoscopic specimens from colorectal lesions.
Author:	Minarikova, Petra\|Benesova, Lucie\|Halkova, Tereza\|Belsanova, Barbora\|Suchanek, Stepan\|Cyrany, Jiri\|Tuckova, Inna\|Bures, Jan\|Zavoral, Miroslav\|Minarik, Marek
PMID:	27239120

2696.
Journal:	Cancer. 2016 Sep 15;122(18):2828-35.
Title:	Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.
Author:	Kothari, Nishi\|Teer, Jamie K\|Abbott, Andrea M\|Srikumar, Thejal\|Zhang, Yonghong\|Yoder, Sean J\|Brohl, Andrew S\|Kim, Richard D\|Reed, Damon R\|Shibata, David
PMID:	27244218

2697.
Journal:	BMC Cancer. 2016 May 31;16:339.
Title:	ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.
Author:	Segelov, Eva\|Waring, Paul\|Desai, Jayesh\|Wilson, Kate\|Gebski, Val\|Thavaneswaran, Subotheni\|Elez, Elena\|Underhill, Craig\|Pavlakis, Nick\|Chantrill, Lorraine\|Nott, Louise\|Jefford, Michael\|Khasraw, Mustafa\|Day, Fiona\|Wasan, Harpreet\|Ciardiello, Fortunato\|Karap
PMID:	27246726

2698.
Journal:	Oncotarget. 2016 Aug 9;7(32):50875-50882.
Title:	Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.
Author:	Javier, Breanna M\|Yaeger, Rona\|Wang, Lu\|Sanchez-Vega, Francisco\|Zehir, Ahmet\|Middha, Sumit\|Sadowska, Justyna\|Vakiani, Efsevia\|Shia, Jinru\|Klimstra, David\|Ladanyi, Marc\|Iacobuzio-Donahue, Christine A\|Hechtman, Jaclyn F
PMID:	27248473

2699.
Journal:	Cancer Biol Ther. 2016 Aug 2;17(8):840-8.
Title:	BRAF V600E mutation in metastatic colorectal cancer: Methods of detection and correlation with clinical and pathologic features.
Author:	Roma, Cristin\|Rachiglio, Anna Maria\|Pasquale, Raffaella\|Fenizia, Francesca\|Iannaccone, Alessia\|Tatangelo, Fabiana\|Antinolfi, Giuseppe\|Parrella, Paola\|Graziano, Paolo\|Sabatino, Lina\|Colantuoni, Vittorio\|Botti, Gerardo\|Maiello, Evaristo\|Normanno, Nicola
PMID:	27261210

2700.
Journal:	Mol Med. 2016 Sep;22:271-273.
Title:	The prognostic yield of biomarkers harvested in chemotherapy-naive stage II colon cancer: can we separate the wheat from the chaff?
Author:	Watson, Martin M\|Soreide, Kjetil
PMID:	27262159

2701.
Journal:	Toxicol Lett. 2016 Aug 22;257:84-96.
Title:	Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study.
Author:	Asif, Muhammad\|Shafaei, Armaghan\|Jafari, Seyedeh Fatemeh\|Mohamed, Shazmin Kithur\|Ezzat, Mohammed Oday\|Abdul Majid, Aman Shah\|Oon, Chern Ein\|Petersen, Sven H\|Kono, Koji\|Abdul Majid, Amin Malik Shah
PMID:	27268964

2702.
Journal:	Med Oncol. 2016 Jul;33(7):71.
Title:	Comparison of KRAS mutation status between primary tumor and metastasis in Chinese colorectal cancer patients.
Author:	Li, Zhe-Zhen\|Bai, Long\|Wang, Feng\|Zhang, Zi-Chen\|Wang, Fang\|Zeng, Zhao-Lei\|Zeng, Jun-Bo\|Zhang, Dong-Sheng\|Wang, Feng-Hua\|Wang, Zhi-Qiang\|Li, Yu-Hong\|Shao, Jian-Yong\|Xu, Rui-Hua
PMID:	27270901

2703.
Journal:	Br J Cancer. 2016 Jun 14;114(12):1352-61.
Title:	Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
Author:	Lee, Michael S\|McGuffey, Elizabeth J\|Morris, Jeffrey S\|Manyam, Ganiraju\|Baladandayuthapani, Veerabahdran\|Wei, Wei\|Morris, Van K\|Overman, Michael J\|Maru, Dipen M\|Jiang, Zhi-Qin\|Hamilton, Stanley R\|Kopetz, Scott
PMID:	27272216

2704.
Journal:	PLoS One. 2016 Jun 8;11(6):e0156540.
Title:	Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers.
Author:	Shapira, Shiran\|Pleban, Shlomo\|Kazanov, Diana\|Tirosh, Peter\|Arber, Nadir
PMID:	27275783

2705.
Journal:	Oncotarget. 2016 Jun 28;7(26):39293-39301.
Title:	Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance.
Author:	Modos, Orsolya\|Reis, Henning\|Niedworok, Christian\|Rubben, Herbert\|Szendroi, Attila\|Szasz, Marcell A\|Timar, Jozsef\|Baghy, Kornelia\|Kovalszky, Ilona\|Golabek, Tomasz\|Chlosta, Piotr\|Okon, Krzysztof\|Peyronnet, Benoit\|Mathieu, Romain\|Shariat, Shahrokh F\|Hollosi
PMID:	27283768

2706.
Journal:	Mol Clin Oncol. 2016 Jun;4(6):1017-1024.
Title:	Efficacy of cetuximab-based chemotherapy in metastatic colorectal cancer according to RAS and BRAF mutation subgroups: A meta-analysis.
Author:	Lin, L I\|Chen, Lu-Lu\|Wang, You\|Meng, Xiang-Yu\|Liang, Chen\|Zhou, Fu-Xiang
PMID:	27284437

2707.
Journal:	J Mol Diagn. 2016 Jul;18(4):546-53.
Title:	Hybridization-Induced Aggregation Technology for Practical Clinical Testing: KRAS Mutation Detection in Lung and Colorectal Tumors.
Author:	Sloane, Hillary S\|Landers, James P\|Kelly, Kimberly A
PMID:	27289420

2708.
Journal:	Nat Chem Biol. 2016 Aug;12(8):593-600.
Title:	Small-molecule binding of the axin RGS domain promotes beta-catenin and Ras degradation.
Author:	Cha, Pu-Hyeon\|Cho, Yong-Hee\|Lee, Sang-Kyu\|Lee, JaeHeon\|Jeong, Woo-Jeong\|Moon, Byoung-San\|Yun, Ji-Hye\|Yang, Jee Sun\|Choi, Sooho\|Yoon, Juyong\|Kim, Hyun-Yi\|Kim, Mi-Yeon\|Kaduwal, Saluja\|Lee, Weontae\|Min, Do Sik\|Kim, Hoguen\|Han, Gyoonhee\|Choi, Kang-Yell
PMID:	27294323

2709.
Journal:	PLoS One. 2016 Jun 14;11(6):e0156659.
Title:	Clinicopathologic and Molecular Features of Colorectal Adenocarcinoma with Signet-Ring Cell Component.
Author:	Wei, Qing\|Wang, Xicheng\|Gao, Jing\|Li, Jian\|Li, Jie\|Qi, Changsong\|Li, Yanyan\|Li, Zhongwu\|Shen, Lin
PMID:	27300552

2710.
Journal:	Nat Commun. 2016 Jun 15;7:11743.
Title:	A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC.
Author:	Schell, Michael J\|Yang, Mingli\|Teer, Jamie K\|Lo, Fang Yin\|Madan, Anup\|Coppola, Domenico\|Monteiro, Alvaro N A\|Nebozhyn, Michael V\|Yue, Binglin\|Loboda, Andrey\|Bien-Willner, Gabriel A\|Greenawalt, Danielle M\|Yeatman, Timothy J
PMID:	27302369

2711.
Journal:	Gastroenterology. 2016 Sep;151(3):440-447.e1.
Title:	Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes.
Author:	Cohen, Stacey A\|Turner, Emily H\|Beightol, Mallory B\|Jacobson, Angela\|Gooley, Ted A\|Salipante, Stephen J\|Haraldsdottir, Sigurdis\|Smith, Christina\|Scroggins, Sheena\|Tait, Jonathan F\|Grady, William M\|Lin, Edward H\|Cohn, David E\|Goodfellow, Paul J\|Arnold, Mar
PMID:	27302833

2712.
Journal:	Am J Surg Pathol. 2016 Oct;40(10):1352-9.
Title:	RNF43 Is an Early and Specific Mutated Gene in the Serrated Pathway, With Increased Frequency in Traditional Serrated Adenoma and Its Associated Malignancy.
Author:	Tsai, Jia-Huei\|Liau, Jau-Yu\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Tseng, Li-Hui\|Cheng, Mei-Ling\|Jeng, Yung-Ming
PMID:	27305845

2713.
Journal:	Mol Oncol. 2016 Oct;10(8):1221-31.
Title:	Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery.
Author:	Denis, Jerome Alexandre\|Patroni, Alexia\|Guillerm, Erell\|Pepin, Dominique\|Benali-Furet, Naoual\|Wechsler, Janine\|Manceau, Gilles\|Bernard, Maguy\|Coulet, Florence\|Larsen, Annette K\|Karoui, Mehdi\|Lacorte, Jean-Marc
PMID:	27311775

2714.
Journal:	Cancer Res. 2016 Aug 1;76(15):4504-15.
Title:	Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer.
Author:	Oddo, Daniele\|Sennott, Erin M\|Barault, Ludovic\|Valtorta, Emanuele\|Arena, Sabrina\|Cassingena, Andrea\|Filiciotto, Genny\|Marzolla, Giulia\|Elez, Elena\|van Geel, Robin M J M\|Bartolini, Alice\|Crisafulli, Giovanni\|Boscaro, Valentina\|Godfrey, Jason T\|Buscarino, M
PMID:	27312529

2715.
Journal:	Oncotarget. 2016 Jul 19;7(29):46158-46172.
Title:	Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism.
Author:	Wei, Zhiliang\|Cao, Shougen\|Liu, Shanglong\|Yao, Zengwu\|Sun, Teng\|Li, Yi\|Li, Jiante\|Zhang, Dongfeng\|Zhou, Yanbing
PMID:	27323816

2716.
Journal:	Oncotarget. 2016 Jul 26;7(30):47954-47965.
Title:	Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer.
Author:	Aguilera, Oscar\|Munoz-Sagastibelza, Maria\|Torrejon, Blanca\|Borrero-Palacios, Aurea\|Del Puerto-Nevado, Laura\|Martinez-Useros, Javier\|Rodriguez-Remirez, Maria\|Zazo, Sandra\|Garcia, Estela\|Fraga, Mario\|Rojo, Federico\|Garcia-Foncillas, Jesus
PMID:	27323830

2717.
Journal:	Virchows Arch. 2016 Aug;469(2):125-34.
Title:	Molecular pathological classification of colorectal cancer.
Author:	Muller, Mike F\|Ibrahim, Ashraf E K\|Arends, Mark J
PMID:	27325016

2718.
Journal:	Br J Cancer. 2016 Jun 28;115(1):40-51.
Title:	FAT1: a potential target for monoclonal antibody therapy in colon cancer.
Author:	Pileri, Piero\|Campagnoli, Susanna\|Grandi, Alberto\|Parri, Matteo\|De Camilli, Elisa\|Song, Chaojun\|Ganfini, Luisa\|Lacombe, Aurelien\|Naldi, Ilaria\|Sarmientos, Paolo\|Cinti, Caterina\|Jin, Boquan\|Grandi, Guido\|Viale, Giuseppe\|Terracciano, Luigi\|Grifantini, Renat
PMID:	27328312

2719.
Journal:	Biomol Detect Quantif. 2016 Jun 6;8:29-32.
Title:	Diagnostic RAS mutation analysis by polymerase chain reaction (PCR).
Author:	Cree, Ian A
PMID:	27335808

2720.
Journal:	Nature. 2016 Jun 30;534(7609):647-51.
Title:	A combinatorial strategy for treating KRAS-mutant lung cancer.
Author:	Manchado, Eusebio\|Weissmueller, Susann\|Morris, John P 4th\|Chen, Chi-Chao\|Wullenkord, Ramona\|Lujambio, Amaia\|de Stanchina, Elisa\|Poirier, John T\|Gainor, Justin F\|Corcoran, Ryan B\|Engelman, Jeffrey A\|Rudin, Charles M\|Rosen, Neal\|Lowe, Scott W
PMID:	27338794

2721.
Journal:	Mol Cell Proteomics. 2016 Sep;15(9):2924-38.
Title:	Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer.
Author:	Hutton, Josiah E\|Wang, Xiaojing\|Zimmerman, Lisa J\|Slebos, Robbert J C\|Trenary, Irina A\|Young, Jamey D\|Li, Ming\|Liebler, Daniel C
PMID:	27340238

2722.
Journal:	Cancer J. 2016 May-Jun;22(3):149-55.
Title:	Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.
Author:	Dienstmann, Rodrigo\|Tabernero, Josep
PMID:	27341591

2723.
Journal:	Cancer Chemother Pharmacol. 2016 Aug;78(2):397-403.
Title:	Panitumumab in combination with irinotecan plus S-1 (IRIS) as second-line therapy for metastatic colorectal cancer.
Author:	Takaoka, Toshi\|Kimura, Tetsuo\|Shimoyama, Rai\|Kawamoto, Shunji\|Sakamoto, Kazuki\|Goda, Fuminori\|Miyamoto, Hiroshi\|Negoro, Yuji\|Tsuji, Akihito\|Yoshizaki, Koji\|Goji, Takahiro\|Kitamura, Shinji\|Yano, Hiromi\|Okamoto, Koichi\|Kimura, Masako\|Okahisa, Toshiya\|Muguru
PMID:	27342247

2724.
Journal:	Biochim Biophys Acta. 2016 Aug;1866(1):51-63.
Title:	Targeting the serrated pathway of colorectal cancer with mutation in BRAF.
Author:	Matos, Paulo\|Goncalves, Vania\|Jordan, Peter
PMID:	27345584

2725.
Journal:	Hum Pathol. 2016 Oct;56:163-70.
Title:	High frequency of KRAS mutation in early onset colorectal adenocarcinoma: implications for pathogenesis.
Author:	Watson, Rao\|Liu, Ta-Chiang\|Ruzinova, Marianna B
PMID:	27346571

2726.
Journal:	Oncol Lett. 2016 Jul;12(1):150-156.
Title:	A comparison of four methods for detecting KRAS mutations in formalin-fixed specimens from metastatic colorectal cancer patients.
Author:	Matsunaga, Mototsugu\|Kaneta, Toshikado\|Miwa, Keisuke\|Ichikawa, Wataru\|Fujita, Ken-Ichi\|Nagashima, Fumio\|Furuse, Junji\|Kage, Masayoshi\|Akagi, Yoshito\|Sasaki, Yasutsuna
PMID:	27347117

2727.
Journal:	Ann Surg Oncol. 2016 Oct;23(11):3736-3743.
Title:	Prognostic Implication of KRAS Status after Hepatectomy for Colorectal Liver Metastases Varies According to Primary Colorectal Tumor Location.
Author:	Sasaki, Kazunari\|Margonis, Georgios A\|Wilson, Ana\|Kim, Yuhree\|Buettner, Stefan\|Andreatos, Nikolaos\|Gani, Faiz\|Amini, Neda\|Spolverato, Gaya\|Pawlik, Timothy M
PMID:	27352204

2728.
Journal:	Mol Cancer Res. 2016 Sep;14(9):795-804.
Title:	Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development.
Author:	Mo, Allen\|Jackson, Stephen\|Varma, Kamini\|Carpino, Alan\|Giardina, Charles\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	27353028

2729.
Journal:	J Nat Prod. 2016 Jul 22;79(7):1867-71.
Title:	Caldoramide, a Modified Pentapeptide from the Marine Cyanobacterium Caldora penicillata.
Author:	Gunasekera, Sarath P\|Imperial, Lorelie\|Garst, Christiana\|Ratnayake, Ranjala\|Dang, Long H\|Paul, Valerie J\|Luesch, Hendrik
PMID:	27380142

2730.
Journal:	J Gastrointest Surg. 2016 Nov;20(11):1821-1829.
Title:	Tumor Biology Rather Than Surgical Technique Dictates Prognosis in Colorectal Cancer Liver Metastases.
Author:	Margonis, Georgios Antonios\|Sasaki, Kazunari\|Kim, Yuhree\|Samaha, Mario\|Buettner, Stefan\|Amini, Neda\|Antoniou, Efstathios\|Pawlik, Timothy M
PMID:	27384430

2731.
Journal:	Oncotarget. 2016 Aug 2;7(31):50290-50301.
Title:	Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Author:	Pitts, Todd M\|Bradshaw-Pierce, Erica L\|Bagby, Stacey M\|Hyatt, Stephanie L\|Selby, Heather M\|Spreafico, Anna\|Tentler, John J\|McPhillips, Kelly\|Klauck, Peter J\|Capasso, Anna\|Diamond, Jennifer R\|Davis, S Lindsey\|Tan, Aik Choon\|Arcaroli, John J\|Purkey, Alicia\|
PMID:	27385211

2732.
Journal:	Oncotarget. 2016 Aug 23;7(34):55098-55109.
Title:	Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival.
Author:	Mima, Kosuke\|Nowak, Jonathan A\|Qian, Zhi Rong\|Cao, Yin\|Song, Mingyang\|Masugi, Yohei\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Hamada, Tsuyoshi\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Baba, Hideo\|Giovannucci, Edward L\|Chan, Andrew T\|Fuch
PMID:	27391152

2733.
Journal:	Diagn Pathol. 2016 Jul 8;11(1):61.
Title:	In depth evaluation of the prognostic and predictive utility of PTEN immunohistochemistry in colorectal carcinomas: performance of three antibodies with emphasis on intracellular and intratumoral heterogeneity.
Author:	Agoston, Emese Irma\|Micsik, Tamas\|Acs, Balazs\|Fekete, Krisztina\|Hahn, Oszkar\|Baranyai, Zsolt\|Dede, Kristof\|Bodoky, Gyorgy\|Bursics, Attila\|Kulka, Janina\|Krenacs, Tibor\|Gyorffy, Balazs\|Harsanyi, Laszlo\|Szasz, A Marcell
PMID:	27392434

2734.
Journal:	Am J Surg. 2016 Sep;212(3):537-544.e3.
Title:	Mutation spectra of RAS gene family in colorectal cancer.
Author:	Chang, Yu-Yao\|Lin, Pei-Ching\|Lin, Hung-Hsin\|Lin, Jen-Kou\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Yang, Shung-Haur\|Liang, Wen-Yih\|Chang, Shih-Ching
PMID:	27394063

2735.
Journal:	Virchows Arch. 2016 Oct;469(4):459-64.
Title:	Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.
Author:	Grellety, Thomas\|Gros, Audrey\|Pedeutour, Florence\|Merlio, Jean-Philippe\|Duranton-Tanneur, Valerie\|Italiano, Antoine\|Soubeyran, Isabelle
PMID:	27401719

2736.
Journal:	Oncology. 2016;91(3):162-70.
Title:	Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis.
Author:	Amaki-Takao, Misato\|Yamaguchi, Tatsuro\|Natsume, Soichiro\|Iijima, Takeru\|Wakaume, Rika\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Miyaki, Michiko
PMID:	27404270

2737.
Journal:	BMC Cancer. 2016 Jul 12;16:454.
Title:	Highly sensitive detection of the PIK3CA (H1047R) mutation in colorectal cancer using a novel PCR-RFLP method.
Author:	Li, Wan-Ming\|Hu, Ting-Ting\|Zhou, Lin-Lin\|Feng, Yi-Ming\|Wang, Yun-Yi\|Fang, Jin
PMID:	27405731

2738.
Journal:	Oncotarget. 2016 Aug 2;7(31):50575-50581.
Title:	Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature.
Author:	Guo, Sheng\|Chen, Dawei\|Huang, Xuesong\|Cai, Jie\|Wery, Jean-Pierre\|Li, Qi-Xiang
PMID:	27409671

2739.
Journal:	Virchows Arch. 2016 Oct;469(4):395-404.
Title:	HIF-1alpha expression and high microvessel density are characteristic features in serrated colorectal cancer.
Author:	Tuomisto, Anne\|Garcia-Solano, Jose\|Sirnio, Paivi\|Vayrynen, Juha\|Perez-Guillermo, Miguel\|Makinen, Markus J\|Conesa-Zamora, Pablo
PMID:	27421843

2740.
Journal:	Int J Mol Med. 2016 Sep;38(3):687-702.
Title:	Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.
Author:	Silva, Patricia\|Albuquerque, Cristina\|Lage, Pedro\|Fontes, Vanessa\|Fonseca, Ricardo\|Vitoriano, Ines\|Filipe, Bruno\|Rodrigues, Paula\|Moita, Susana\|Ferreira, Sara\|Sousa, Rita\|Claro, Isabel\|Nobre Leitao, Carlos\|Chaves, Paula\|Dias Pereira, Antonio
PMID:	27430658

2741.
Journal:	Int J Clin Oncol. 2016 Dec;21(6):1091-1101.
Title:	CpG island methylator phenotype is associated with the efficacy of sequential oxaliplatin- and irinotecan-based chemotherapy and EGFR-related gene mutation in Japanese patients with metastatic colorectal cancer.
Author:	Zhang, Xiaofei\|Shimodaira, Hideki\|Soeda, Hiroshi\|Komine, Keigo\|Takahashi, Hidekazu\|Ouchi, Kota\|Inoue, Masahiro\|Takahashi, Masanobu\|Takahashi, Shin\|Ishioka, Chikashi
PMID:	27435270

2742.
Journal:	Cancer Chemother Pharmacol. 2016 Sep;78(3):567-75.
Title:	A phase I study of the combination of panitumumab and bevacizumab in KRAS wild-type colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, irinotecan and bevacizumab.
Author:	Takahashi, Naoki\|Iwasa, Satoru\|Fukahori, Masaru\|Sudo, Kazuki\|Sasaki, Yusuke\|Shoji, Hirokazu\|Honma, Yoshitaka\|Okita, Natsuko Tsuda\|Takashima, Atsuo\|Hamaguchi, Tetsuya\|Boku, Narikazu\|Shimada, Yasuhiro\|Honda, Kazufumi\|Yamada, Tesshi\|Yamada, Yasuhide
PMID:	27438067

2743.
Journal:	Am J Surg Pathol. 2016 Oct;40(10):1390-9.
Title:	MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas.
Author:	Farchoukh, Lama\|Kuan, Shih-Fan\|Dudley, Beth\|Brand, Randall\|Nikiforova, Marina\|Pai, Reetesh K
PMID:	27438990

2744.
Journal:	PLoS One. 2016 Jul 21;11(7):e0157751.
Title:	Treatment of Metastatic Colorectal Cancer Patients >/=75 Years Old in Clinical Practice: A Multicenter Analysis.
Author:	Grande, Roberta\|Natoli, Clara\|Ciancola, Fabrizio\|Gemma, Donatello\|Pellegrino, Arianna\|Pavese, Ida\|Garufi, Carlo\|Di Lauro, Luigi\|Corsi, Domenico\|Signorelli, Diego\|Sperduti, Isabella\|Cortese, Giada\|Risi, Emanuela\|Morano, Federica\|Sergi, Domenico\|Signorelli,
PMID:	27442239

2745.
Journal:	World J Surg Oncol. 2016 Jul 22;14(1):189.
Title:	Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.
Author:	Schmitz, Klaus Juergen\|Ademi, Ceflije\|Bertram, Stefanie\|Schmid, Kurt Werner\|Baba, Hideo Andreas
PMID:	27444698

2746.
Journal:	Oncol Lett. 2016 Aug;12(2):1415-1421.
Title:	Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma.
Author:	Palomba, Grazia\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Pazzola, Antonio\|Baldino, Giovanni\|Scartozzi, Mario\|Ionta, Maria Teresa\|Ortu, Salvatore\|Capelli, Francesca\|Lanzillo, Annamaria\|Sedda, Tito\|Sanna, Giovanni\|Barca, Michela\|Virdis, Luciano\|Budroni, Mari
PMID:	27446446

2747.
Journal:	Mol Clin Oncol. 2016 Aug;5(2):375-379.
Title:	First-line cetuximab-based chemotherapies for patients with advanced or metastatic KRAS wild-type colorectal cancer.
Author:	Uemura, Mamoru\|Kim, Ho Min\|Hata, Tsuyoshi\|Sakata, Kazuya\|Okuyama, Masaki\|Takemoto, Hiroyoshi\|Fujii, Hitoshi\|Fukuzaki, Takayuki\|Morita, Tetsushi\|Hata, Taishi\|Takemasa, Ichiro\|Satoh, Taroh\|Mizushima, Tsunekazu\|Doki, Yuichiro\|Mori, Maski
PMID:	27446583

2748.
Journal:	Oncotarget. 2016 Oct 11;7(41):66595-66605.
Title:	Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma.
Author:	Rachiglio, Anna Maria\|Esposito Abate, Riziero\|Sacco, Alessandra\|Pasquale, Raffaella\|Fenizia, Francesca\|Lambiase, Matilde\|Morabito, Alessandro\|Montanino, Agnese\|Rocco, Gaetano\|Romano, Carmen\|Nappi, Anna\|Iaffaioli, Rosario Vincenzo\|Tatangelo, Fabiana\|Botti,
PMID:	27448974

2749.
Journal:	Oncotarget. 2016 Aug 16;7(33):53153-53164.
Title:	KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway.
Author:	Liu, Yan\|Wang, Shu-Qing\|Long, Yue-Hong\|Chen, Su\|Li, Yu-Feng\|Zhang, Jing-Hua
PMID:	27449290

2750.
Journal:	Gastroenterology. 2016 Nov;151(5):945-960.e6.
Title:	SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.
Author:	Wong, Chi Chun\|Qian, Yun\|Li, Xiaona\|Xu, Jiaying\|Kang, Wei\|Tong, Joanna H\|To, Ka-Fai\|Jin, Ye\|Li, Weilin\|Chen, Huarong\|Go, Minnie Y Y\|Wu, Jian-Lin\|Cheng, Ka Wing\|Ng, Simon S M\|Sung, Joseph J Y\|Cai, Zongwei\|Yu, Jun
PMID:	27451147

2751.
Journal:	Nat Mater. 2016 Oct;15(10):1128-38.
Title:	Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model.
Author:	Conde, Joao\|Oliva, Nuria\|Zhang, Yi\|Artzi, Natalie
PMID:	27454043

2752.
Journal:	Oncol Rep. 2016 Sep;36(3):1672-8.
Title:	GATA binding protein 2 overexpression is associated with poor prognosis in KRAS mutant colorectal cancer.
Author:	Xu, Kai\|Wang, Jiayuan\|Gao, Jing\|Di, Jiabo\|Jiang, Beihai\|Chen, Lei\|Wang, Zaozao\|Wang, Aidong\|Wu, Fan\|Wu, Wei\|Shen, Lin\|Su, Xiangqian
PMID:	27460045

2753.
Journal:	BMC Cancer. 2016 Jul 26;16:531.
Title:	Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells.
Author:	Risberg, Karianne\|Redalen, Kathrine Roe\|Sonstevold, Linda\|Bjornetro, Tonje\|Solvernes, Janne\|Ree, Anne Hansen
PMID:	27461218

2754.
Journal:	J Biomol Screen. 2016 Oct;21(9):989-97.
Title:	Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Author:	Severyn, Bryan\|Nguyen, Thi\|Altman, Michael D\|Li, Lixia\|Nagashima, Kumiko\|Naumov, George N\|Sathyanarayanan, Sriram\|Cook, Erica\|Morris, Erick\|Ferrer, Marc\|Arthur, Bill\|Benita, Yair\|Watters, Jim\|Loboda, Andrey\|Hermes, Jeff\|Gilliland, D Gary\|Cleary, Michelle
PMID:	27461835

2755.
Journal:	Cancer Med. 2016 Sep;5(9):2249-60.
Title:	Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance).
Author:	Hatch, Ace J\|Sibley, Alexander B\|Starr, Mark D\|Brady, J Chris\|Jiang, Chen\|Jia, Jingquan\|Bowers, Daniel L\|Pang, Herbert\|Owzar, Kouros\|Niedzwiecki, Donna\|Innocenti, Federico\|Venook, Alan P\|Hurwitz, Herbert I\|Nixon, Andrew B
PMID:	27465221

2756.
Journal:	Anticancer Res. 2016 Aug;36(8):4233-6.
Title:	Lack of Relationship Between Clinical Features and KRAS Mutations in Patients with Metastatic Colorectal Cancer.
Author:	Ploquin, Anne\|Zerimech, Farid\|Escande, Fabienne\|Adenis, Antoine\|Giraud, Claire\|Gasnault, Laurent\|Bourgeois, Vincent\|Desauw, Christophe\|Hebbar, Mohamed
PMID:	27466537

2757.
Journal:	Cancer Chemother Pharmacol. 2016 Sep;78(3):585-93.
Title:	Multicenter phase II study of combination therapy with cetuximab and S-1 in patients with KRAS exon 2 wild-type unresectable colorectal cancer previously treated with irinotecan, oxaliplatin, and fluoropyrimidines (KSCC 0901 study).
Author:	Takahashi, Takao\|Emi, Yasunori\|Oki, Eiji\|Kobayashi, Kazuma\|Tsuji, Akihito\|Shimokawa, Mototsugu\|Tanaka, Takaho\|Akagi, Yoshito\|Ogata, Yutaka\|Baba, Hideo\|Yoshida, Kazuhiro\|Natsugoe, Shoji\|Maehara, Yoshihiko
PMID:	27468920

2758.
Journal:	BMB Rep. 2016 Sep;49(9):455-6.
Title:	Simultaneous destabilization of beta-catenin and Ras via targeting of the axin-RGS domain as a potential therapeutic strategy for colorectal cancer.
Author:	Cha, Pu-Hyeon\|Choi, Kang-Yell
PMID:	27470214

2759.
Journal:	Protein Cell. 2016 Aug;7(8):571-85.
Title:	Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Author:	Shan, Jianzhen\|Xuan, Yanyan\|Zhang, Qi\|Zhu, Chunpeng\|Liu, Zhen\|Zhang, Suzhan
PMID:	27472952

2760.
Journal:	Free Radic Biol Med. 2016 Aug;97:620.
Title:	Corrigendum to 'L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells': [Free Radic. Biol. Med. 95 (2016) 200-208].
Author:	Jung, S A\|Lee, D H\|Moon, J H\|Hong, S W\|Shin, J S\|Hwang, I Y\|Shin, Y J\|Kim, J H\|Gong, E Y\|Kim, S M\|Lee, E Y\|Lee, S\|Kim, J E\|Kim, K P\|Hong, Y S\|Lee, J S\|Jin, D H\|Kim, T\|Lee, W J
PMID:	27476024

2761.
Journal:	Cancer Res. 2016 Aug 1;76(15):4309-10.
Title:	Commentary on "KRAS Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer".
Author:	Benjamin, Laura E
PMID:	27480959

2762.
Journal:	BMC Cancer. 2016 Aug 2;16:585.
Title:	A rational two-step approach to KRAS mutation testing in colorectal cancer using high resolution melting analysis and pyrosequencing.
Author:	Mack, Elisabeth\|Stabla, Kathleen\|Riera-Knorrenschild, Jorge\|Moll, Roland\|Neubauer, Andreas\|Brendel, Cornelia
PMID:	27485514

2763.
Journal:	Oncotarget. 2016 Sep 20;7(38):61312-61324.
Title:	miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression.
Author:	Ye, Ya-Ping\|Wu, Ping\|Gu, Chun-Cai\|Deng, Dan-Ling\|Jiao, Hong-Li\|Li, Ting-Ting\|Wang, Shu-Yang\|Wang, Yong-Xia\|Xiao, Zhi-Yuan\|Wei, Wen-Ting\|Chen, Yan-Ru\|Qiu, Jun-Feng\|Yang, Run-Wei\|Lin, Jie\|Liang, Li\|Liao, Wen-Ting\|Ding, Yan-Qing
PMID:	27494869

2764.
Journal:	J Pathol Clin Res. 2015 Oct 28;2(1):21-31.
Title:	The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer.
Author:	Ling, Agnes\|Lundberg, Ida V\|Eklof, Vincy\|Wikberg, Maria L\|Oberg, Ake\|Edin, Sofia\|Palmqvist, Richard
PMID:	27499912

2765.
Journal:	J Pathol Clin Res. 2016 Apr 22;2(3):127-37.
Title:	The molecular characteristics of colonic neoplasms in serrated polyposis: a systematic review and meta-analysis.
Author:	He, Emily Y\|Wyld, Lucy\|Sloane, Mathew A\|Canfell, Karen\|Ward, Robyn L
PMID:	27499922

2766.
Journal:	J Pathol Clin Res. 2016 Apr 15;2(3):166-74.
Title:	Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations.
Author:	Crobach, Stijn\|Ruano, Dina\|van Eijk, Ronald\|Schrumpf, Melanie\|Fleuren, Gertjan\|van Wezel, Tom\|Morreau, Hans
PMID:	27499925

2767.
Journal:	Oncotarget. 2016 Sep 13;7(37):59441-59457.
Title:	TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer.
Author:	Tarpgaard, Line S\|Orum-Madsen, Maj Sofie\|Christensen, Ib J\|Nordgaard, Cathrine\|Noer, Julie\|Guren, Tormod K\|Glimelius, Bengt\|Sorbye, Halfdan\|Ikdahl, Tone\|Kure, Elin H\|Tveit, Kjell M\|Nielsen, Hans J\|Pfeiffer, Per\|Brunner, Nils\|Moreira, Jose M A
PMID:	27509063

2768.
Journal:	Int J Cancer. 2016 Dec 1;139(11):2493-501.
Title:	Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer.
Author:	Takahashi, Yayoi\|Sugai, Tamotsu\|Habano, Wataru\|Ishida, Kazuyuki\|Eizuka, Makoto\|Otsuka, Koki\|Sasaki, Akira\|Takayuki Matsumoto\|Morikawa, Takanori\|Unno, Michiaki\|Suzuki, Hiromu
PMID:	27509333

2769.
Journal:	Asian Pac J Cancer Prev. 2016;17(7):3085-8.
Title:	Evaluation of KRAS Gene Mutations in Metastatic Colorectal Cancer Patients in Kermanshah Province.
Author:	Amirifard, Nasrin\|Sadeghi, Edris\|Farshchian, Negin\|Haghparast, Abbas\|Choubsaz, Mansour
PMID:	27509933

2770.
Journal:	Asian Pac J Cancer Prev. 2016;17(7):3417-22.
Title:	Clinicopathological Features and Survival Rate of Colorectal Adenocarcinoma Patients with and without a KRAS Mutation: a FiveYear Study in Yazd, Iran.
Author:	Zahir, Shokouh Taghipour\|NazemianYazdi, Mohammadreza\|Arasteh, Peyman\|Mortazavizadeh, Mohammadreza\|Karbalaeian, Mohammad\|ZareMehrjardi, Malihe
PMID:	27509985

2771.
Journal:	Rom J Morphol Embryol. 2016;57(2):445-50.
Title:	Histoprognostic markers role in colorectal cancer.
Author:	Badulescu, Florinel\|Mihai, Gabriela Marcelina\|Badulescu, Adriana\|Prejbeanu, Ileana
PMID:	27516017

2772.
Journal:	Gastroenterology. 2016 Nov;151(5):961-972.
Title:	Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer.
Author:	Martinez-Cardus, Anna\|Moran, Sebastian\|Musulen, Eva\|Moutinho, Catia\|Manzano, Jose L\|Martinez-Balibrea, Eva\|Tierno, Montserrat\|Elez, Elena\|Landolfi, Stefania\|Lorden, Patricia\|Arribas, Carles\|Muller, Fabian\|Bock, Christoph\|Tabernero, Josep\|Esteller, Manel
PMID:	27521480

2773.
Journal:	Oncogenesis. 2016 Aug 15;5(8):e253.
Title:	KRAS mutation leads to decreased expression of regulator of calcineurin 2, resulting in tumor proliferation in colorectal cancer.
Author:	Niitsu, H\|Hinoi, T\|Kawaguchi, Y\|Sentani, K\|Yuge, R\|Kitadai, Y\|Sotomaru, Y\|Adachi, T\|Saito, Y\|Miguchi, M\|Kochi, M\|Sada, H\|Shimomura, M\|Oue, N\|Yasui, W\|Ohdan, H
PMID:	27526107

2774.
Journal:	Acta Medica (Hradec Kralove). 2016;59(2):54-8.
Title:	Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer.
Author:	Beranek, Martin\|Sirak, Igor\|Vosmik, Milan\|Petera, Jiri\|Drastikova, Monika\|Palicka, Vladimir
PMID:	27526306

2775.
Journal:	Gan To Kagaku Ryoho. 2016 Aug;43(8):1009-13.
Title:	[A Case of Rectal Neuroendocrine Carcinoma with Metachronous Liver Metastasis Treated with Multimodality Therapy].
Author:	Miyamae, Yohei\|Shimizu, Hisashi\|Naganuma, Atsushi\|Aiba, Masaaki\|Tanaka, Toshiyuki\|Ogawa, Tetsushi\|Ogawa, Akira\|Osamura, Yoshiyuki
PMID:	27539046

2776.
Journal:	Cancer Biomark. 2016 Jun 24;17(2):133-43.
Title:	KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
Author:	Bagci, Binnur\|Sari, Musa\|Karadayi, Kursat\|Turan, Mustafa\|Ozdemir, Ozturk\|Bagci, Gokhan
PMID:	27540971

2777.
Journal:	J Pediatr Surg. 2016 Nov;51(11):1812-1817.
Title:	Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients.
Author:	Khan, Sajid A\|Morris, Melinda\|Idrees, Kamran\|Gimbel, Mark I\|Rosenberg, Shoshana\|Zeng, Zhaoshi\|Li, Fangyong\|Gan, Geliang\|Shia, Jinru\|LaQuaglia, Michael P\|Paty, Philip B
PMID:	27558481

2778.
Journal:	BMC Cancer. 2016 Aug 25;16(1):683.
Title:	High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Author:	Padhan, Narendra\|Nordling, Torbjorn E M\|Sundstrom, Magnus\|Akerud, Peter\|Birgisson, Helgi\|Nygren, Peter\|Nelander, Sven\|Claesson-Welsh, Lena
PMID:	27562229

2779.
Journal:	Oncotarget. 2016 Dec 20;7(51):84003-84016.
Title:	Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.
Author:	Takane, Kiyoko\|Matsusaka, Keisuke\|Ota, Satoshi\|Fukuyo, Masaki\|Yue, Yao\|Nishimura, Motoi\|Sakai, Eiji\|Matsushita, Kazuyuki\|Miyauchi, Hideaki\|Aburatani, Hiroyuki\|Nakatani, Yukio\|Takayama, Tadatoshi\|Matsubara, Hisahiro\|Akagi, Kiwamu\|Kaneda, Atsushi
PMID:	27563825

2780.
Journal:	Surg Oncol. 2016 Sep;25(3):190-9.
Title:	Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer.
Author:	Ronnekleiv-Kelly, Sean M\|Burkhart, Richard A\|Pawlik, Timothy M
PMID:	27566022

2781.
Journal:	World J Gastroenterol. 2016 Aug 14;22(30):6944-54.
Title:	Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.
Author:	Lo Nigro, Cristiana\|Ricci, Vincenzo\|Vivenza, Daniela\|Granetto, Cristina\|Fabozzi, Teresa\|Miraglio, Emanuela\|Merlano, Marco C
PMID:	27570430

2782.
Journal:	Ann Oncol. 2016 Nov;27(11):2082-2090.
Title:	Subgroup analysis in RAISE: a randomized, double-blind phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab or placebo in patients with metastatic colorectal carcinoma progression.
Author:	Obermannova, R\|Van Cutsem, E\|Yoshino, T\|Bodoky, G\|Prausova, J\|Garcia-Carbonero, R\|Ciuleanu, T\|Garcia Alfonso, P\|Portnoy, D\|Cohn, A\|Yamazaki, K\|Clingan, P\|Lonardi, S\|Kim, T W\|Yang, L\|Nasroulah, F\|Tabernero, J
PMID:	27573561

2783.
Journal:	Br J Cancer. 2016 Sep 27;115(7):814-24.
Title:	gamma-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules.
Author:	Prasad, Sahdeo\|Gupta, Subash C\|Tyagi, Amit K\|Aggarwal, Bharat B
PMID:	27575851

2784.
Journal:	Eur J Surg Oncol. 2016 Oct;42(10):1540-7.
Title:	FOLFIRI plus cetuximab in patients with liver-limited or non-liver-limited RAS wild-type metastatic colorectal cancer: A retrospective subgroup analysis of the CRYSTAL study.
Author:	Kohne, C-H\|Poston, G\|Folprecht, G\|Ciardiello, F\|Ronga, P\|Beier, F\|Van Cutsem, E
PMID:	27575968

2785.
Journal:	Oncotarget. 2016 Oct 4;7(40):65676-65695.
Title:	SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.
Author:	Gagne-Sansfacon, Jessica\|Coulombe, Genevieve\|Langlois, Marie-Josee\|Langlois, Ariane\|Paquet, Marilene\|Carrier, Julie\|Feng, Gen-Sheng\|Qu, Cheng-Kui\|Rivard, Nathalie
PMID:	27582544

2786.
Journal:	Cancer Sci. 2016 Nov;107(11):1705-1716.
Title:	High expression of the Notch ligand Jagged-1 is associated with poor prognosis after surgery for colorectal cancer.
Author:	Sugiyama, Masakazu\|Oki, Eiji\|Nakaji, Yu\|Tsutsumi, Satoshi\|Ono, Naomi\|Nakanishi, Ryota\|Sugiyama, Masahiko\|Nakashima, Yuichiro\|Sonoda, Hideto\|Ohgaki, Kippei\|Yamashita, Nami\|Saeki, Hiroshi\|Okano, Shinji\|Kitao, Hiroyuki\|Morita, Masaru\|Oda, Yoshinao\|Maehara, Y
PMID:	27589478

2787.
Journal:	BMJ Case Rep. 2016 Sep 2;2016. pii: bcr-2016-216273.
Title:	Effect of treatment of rectal cancer metastasis with intravitreal bevacizumab (Avastin) in patient with subretinal fluid and macular oedema: short-term follow-up.
Author:	Boss, Joseph Daniel\|Lieu, Philip\|Tewari, Asheesh
PMID:	27591037

2788.
Journal:	Oncol Lett. 2016 Sep;12(3):1655-1660.
Title:	Low expression of PKCalpha and high expression of KRAS predict poor prognosis in patients with colorectal cancer.
Author:	Chen, Suxian\|Wang, Yadi\|Zhang, Yun\|Wan, Yizeng
PMID:	27602102

2789.
Journal:	Oncotarget. 2016 Oct 18;7(42):68546-68558.
Title:	Specific inhibition of p110alpha subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers.
Author:	Fernandes, Maria Sofia\|Melo, Soraia\|Velho, Sergia\|Carneiro, Patricia\|Carneiro, Fatima\|Seruca, Raquel
PMID:	27602501

2790.
Journal:	World J Gastroenterol. 2016 Aug 21;22(31):7099-110.
Title:	Current understanding concerning intestinal stem cells.
Author:	Cui, Shuang\|Chang, Peng-Yu
PMID:	27610020

2791.
Journal:	Tumour Biol. 2016 Nov;37(11):14415-14425.
Title:	Study of apoptosis-related interactions in colorectal cancer.
Author:	Arora, Himanshu\|Qureshi, Rehana\|Rizvi, M A\|Shrivastava, Sharad\|Parihar, Mordhwaj S
PMID:	27629291

2792.
Journal:	Anticancer Res. 2016 Sep;36(9):4715-23.
Title:	Assessment of Pharmacokinetic Interaction Between Capecitabine and Cetuximab in Metastatic Colorectal Cancer Patients.
Author:	Rachar, Veronika\|Czejka, Martin\|Kitzmueller, Marie\|Buchner, Philipp\|Lichtneckert, Maria\|Greil, Richard\|Geiler, Herbert\|Dittrich, Christian
PMID:	27630318

2793.
Journal:	Anticancer Res. 2016 Sep;36(9):4799-804.
Title:	Prediction of KRAS Mutation in Rectal Cancer Using MRI.
Author:	Shin, Yu Ri\|Kim, Kyung Ah\|Im, Soyoung\|Hwang, Seong Su\|Kim, Kijun
PMID:	27630331

2794.
Journal:	PLoS One. 2016 Sep 15;11(9):e0163070.
Title:	Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific qPCR.
Author:	Orue, Andrea\|Rieber, Manuel
PMID:	27632281

2795.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):180-185.
Title:	[Prognostic biomarkers for metastatic colorectal cancer].
Author:	Neumann, J H L
PMID:	27638531

2796.
Journal:	Mol Cancer Res. 2016 Dec;14(12):1204-1216.
Title:	MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling.
Author:	McNew, Kelsey L\|Whipple, William J\|Mehta, Anita K\|Grant, Trevor J\|Ray, Leah\|Kenny, Connor\|Singh, Anurag
PMID:	27655129

2797.
Journal:	Clin Med Insights Pathol. 2016 Sep 7;9:19-28.
Title:	Oncogene Mutations in Colorectal Polyps Identified in the Norwegian Colorectal Cancer Prevention (NORCCAP) Screening Study.
Author:	Lorentzen, Jon A\|Grzyb, Krzysztof\|De Angelis, Paula M\|Hoff, Geir\|Eide, Tor J\|Andresen, Per Arne
PMID:	27656095

2798.
Journal:	World J Gastrointest Oncol. 2016 Sep 15;8(9):642-55.
Title:	Role of targeted therapy in metastatic colorectal cancer.
Author:	Ohhara, Yoshihito\|Fukuda, Naoki\|Takeuchi, Satoshi\|Honma, Rio\|Shimizu, Yasushi\|Kinoshita, Ichiro\|Dosaka-Akita, Hirotoshi
PMID:	27672422

2799.
Journal:	Oncologist. 2016 Nov;21(11):1306-1314.
Title:	Broad Detection of Alterations Predicted to Confer Lack of Benefit From EGFR Antibodies or Sensitivity to Targeted Therapy in Advanced Colorectal Cancer.
Author:	Rankin, Andrew\|Klempner, Samuel J\|Erlich, Rachel\|Sun, James X\|Grothey, Axel\|Fakih, Marwan\|George, Thomas J Jr\|Lee, Jeeyun\|Ross, Jeffrey S\|Stephens, Philip J\|Miller, Vincent A\|Ali, Siraj M\|Schrock, Alexa B
PMID:	27682134

2800.
Journal:	PLoS One. 2016 Sep 29;11(9):e0163444.
Title:	Multi-Center Evaluation of the Fully Automated PCR-Based Idylla KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer.
Author:	Solassol, Jerome\|Vendrell, Julie\|Markl, Bruno\|Haas, Christian\|Bellosillo, Beatriz\|Montagut, Clara\|Smith, Matthew\|O'Sullivan, Brendan\|D'Haene, Nicky\|Le Mercier, Marie\|Grauslund, Morten\|Melchior, Linea Cecilie\|Burt, Emma\|Cotter, Finbarr\|Stieber, Daniel\|Schm
PMID:	27685259

2801.
Journal:	Br J Cancer. 2016 Nov 8;115(10):1223-1233.
Title:	FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.
Author:	Marzi, L\|Combes, E\|Vie, N\|Ayrolles-Torro, A\|Tosi, D\|Desigaud, D\|Perez-Gracia, E\|Larbouret, C\|Montagut, C\|Iglesias, M\|Jarlier, M\|Denis, V\|Linares, L K\|Lam, E W-F\|Martineau, P\|Del Rio, M\|Gongora, C
PMID:	27685445

2802.
Journal:	Int J Immunopathol Pharmacol. 2016 Dec;29(4):759-763.
Title:	Establishing the colitis-associated cancer progression mouse models.
Author:	Zheng, Haiming\|Lu, Zhanjun\|Wang, Ruhua\|Chen, Niwei\|Zheng, Ping
PMID:	27694612

2803.
Journal:	Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11859-11864.
Title:	Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.
Author:	Tetteh, Paul W\|Kretzschmar, Kai\|Begthel, Harry\|van den Born, Maaike\|Korving, Jeroen\|Morsink, Folkert\|Farin, Henner\|van Es, Johan H\|Offerhaus, G Johan A\|Clevers, Hans
PMID:	27708166

2804.
Journal:	Cancer Sci. 2016 Dec;107(12):1843-1850.
Title:	Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.
Author:	Shitara, Kohei\|Yonesaka, Kimio\|Denda, Tadamichi\|Yamazaki, Kentaro\|Moriwaki, Toshikazu\|Tsuda, Masahiro\|Takano, Toshimi\|Okuda, Hiroyuki\|Nishina, Tomohiro\|Sakai, Kazuko\|Nishio, Kazuto\|Tokunaga, Shoji\|Yamanaka, Takeharu\|Boku, Narikazu\|Hyodo, Ichinosuke\|Muro,
PMID:	27712015

2805.
Journal:	Cancer Lett. 2016 Dec 28;383(2):145-153.
Title:	BAY61-3606 potentiates the anti-tumor effects of TRAIL against colon cancer through up-regulating DR4 and down-regulating NF-kappaB.
Author:	Du, Jipei\|Wang, Yufang\|Chen, Degao\|Ji, Guangyu\|Ma, Qizhao\|Liao, Shiping\|Zheng, Yanjiang\|Zhang, Ji\|Hou, Yiping
PMID:	27721019

2806.
Journal:	Am J Transl Res. 2016 Sep 15;8(9):3822-3830. eCollection 2016.
Title:	A novel E1B55kDa-deleted oncolytic adenovirus carrying microRNA-143 exerts specific antitumor efficacy on colorectal cancer cells.
Author:	Luo, Qifeng\|Basnet, Shiva\|Dai, Zhenling\|Li, Shuping\|Zhang, Zhenyu\|Ge, Haiyan
PMID:	27725862

2807.
Journal:	Oncotarget. 2016 Nov 8;7(45):73876-73887.
Title:	Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.
Author:	van den Broek, Evert\|Krijgsman, Oscar\|Sie, Daoud\|Tijssen, Marianne\|Mongera, Sandra\|van de Wiel, Mark A\|Belt, Eric J Th\|den Uil, Sjoerd H\|Bril, Herman\|Stockmann, Hein B A C\|Ylstra, Bauke\|Carvalho, Beatriz\|Meijer, Gerrit A\|Fijneman, Remond J A
PMID:	27729614

2808.
Journal:	J Transl Med. 2016 Oct 13;14(1):292.
Title:	Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.
Author:	Palomba, Grazia\|Doneddu, Valentina\|Cossu, Antonio\|Paliogiannis, Panagiotis\|Manca, Antonella\|Casula, Milena\|Colombino, Maria\|Lanzillo, Annamaria\|Defraia, Efisio\|Pazzola, Antonio\|Sanna, Giovanni\|Putzu, Carlo\|Ortu, Salvatore\|Scartozzi, Mario\|Ionta, Maria Ter
PMID:	27737711

2809.
Journal:	Cancer Immunol Res. 2016 Nov;4(11):927-935.
Title:	MicroRNA let-7, T Cells, and Patient Survival in Colorectal Cancer.
Author:	Dou, Ruoxu\|Nishihara, Reiko\|Cao, Yin\|Hamada, Tsuyoshi\|Mima, Kosuke\|Masuda, Atsuhiro\|Masugi, Yohei\|Shi, Yan\|Gu, Mancang\|Li, Wanwan\|da Silva, Annacarolina\|Nosho, Katsuhiko\|Zhang, Xuehong\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Chan, Andrew T\|Fuchs, Char
PMID:	27737877

2810.
Journal:	J Gastrointest Oncol. 2016 Oct;7(5):713-720.
Title:	Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others.
Author:	Bupathi, Manojkumar\|Wu, Christina
PMID:	27747085

2811.
Journal:	Eur J Cancer. 2016 Nov;68:114-124.
Title:	The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression.
Author:	Atlasi, Yaser\|Noori, Rubina\|Marolin, Ivana\|Franken, Patrick\|Brandao, Joana\|Biermann, Katharina\|Collini, Paola\|Grigorian, Mariam\|Lukanidin, Eugene\|Ambartsumian, Noona\|Fodde, Riccardo
PMID:	27750112

2812.
Journal:	Expert Rev Pharmacoecon Outcomes Res. 2016 Dec;16(6):667-677.
Title:	Cost-effectiveness of cetuximab for colorectal cancer.
Author:	Park, Taehwan\|Choi, Chang-Ju\|Choi, Yeera\|Suh, Dong-Churl
PMID:	27750444

2813.
Journal:	Adv Exp Med Biol. 2016;924:39-41.
Title:	Screening of KRAS Mutation in Pre- and Post-Surgery Serum of Patients Suffering from Colon Cancer by COLD-PCR HRM.
Author:	Trujillo-Arribas, Elena\|Macher, Hada C\|Jimenez-Arriscado, Pilar\|de la Portilla, Fernando\|Molinero, Patrocinio\|Guerrero, Juan M\|Rubio, Amalia
PMID:	27753016

2814.
Journal:	BMC Med Genomics. 2016 Oct 19;9(1):65.
Title:	Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer.
Author:	Omolo, Bernard\|Yang, Mingli\|Lo, Fang Yin\|Schell, Michael J\|Austin, Sharon\|Howard, Kellie\|Madan, Anup\|Yeatman, Timothy J
PMID:	27756306

2815.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

2816.
Journal:	Neoplasia. 2016 Nov;18(11):654-665.
Title:	Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Author:	Toda, Kosuke\|Kawada, Kenji\|Iwamoto, Masayoshi\|Inamoto, Susumu\|Sasazuki, Takehiko\|Shirasawa, Senji\|Hasegawa, Suguru\|Sakai, Yoshiharu
PMID:	27764698

2817.
Journal:	Br J Cancer. 2016 Nov 8;115(10):1215-1222.
Title:	Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer.
Author:	Karthaus, Meinolf\|Hofheinz, Ralf-Dieter\|Mineur, Laurent\|Letocha, Henry\|Greil, Richard\|Thaler, Josef\|Fernebro, Eva\|Oliner, Kelly S\|Boedigheimer, Michael\|Twomey, Brian\|Zhang, Ying\|Demonty, Gaston\|Kohne, Claus-Henning
PMID:	27764839

2818.
Journal:	Eur J Cancer. 2016 Nov;68:163-172.
Title:	Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer.
Author:	Bouchahda, Mohamed\|Boige, Valerie\|Smith, Denis\|Karaboue, Abdoulaye\|Ducreux, Michel\|Hebbar, Mohamed\|Lepere, Celine\|Focan, Christian\|Guimbaud, Rosine\|Innominato, Pasquale\|Awad, Sameh\|Carvalho, Carlos\|Tumolo, Salvatore\|Truant, Stephanie\|De Baere, Thierry\|Cas
PMID:	27768923

2819.
Journal:	Oncotarget. 2016 Dec 20;7(51):84826-84838.
Title:	MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42.
Author:	Wang, Yong-Xia\|Chen, Yan-Ru\|Liu, Shan-Shan\|Ye, Ya-Ping\|Jiao, Hong-Li\|Wang, Shu-Yang\|Xiao, Zhi-Yuan\|Wei, Wen-Ting\|Qiu, Jun-Feng\|Liang, Li\|Liao, Wen-Ting\|Ding, Yan-Qing
PMID:	27769041

2820.
Journal:	World J Clin Oncol. 2016 Oct 10;7(5):340-351.
Title:	Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer.
Author:	Sobani, Zain A\|Sawant, Ashwin\|Jafri, Mikram\|Correa, Amit Keith\|Sahin, Ibrahim Halil
PMID:	27777877

2821.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Oct 25;19(10):1197-1200.
Title:	[Research progress of serrated polyposis syndrome].
Author:	Dong, Shihao\|Chen, Jingsong
PMID:	27781259

2822.
Journal:	PLoS One. 2016 Oct 31;11(10):e0165581.
Title:	Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome.
Author:	Lin, Jason\|Hiraoka, Kiriko\|Watanabe, Takayoshi\|Kuo, Tony\|Shinozaki, Yoshinao\|Takatori, Atsushi\|Koshikawa, Nobuko\|Chandran, Anandhakumar\|Otsuki, Joe\|Sugiyama, Hiroshi\|Horton, Paul\|Nagase, Hiroki
PMID:	27798693

2823.
Journal:	Anticancer Res. 2016 Oct;36(10):5315-5324.
Title:	KRAS Mutant Status, p16 and beta-catenin Expression May Predict Local Recurrence in Patients Who Underwent Transanal Endoscopic Microsurgery (TEMS) for Stage I Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Bjarnason, Ingvar\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	27798894

2824.
Journal:	Oncol Rep. 2016 Dec;36(6):3627-3634.
Title:	In silico RNA-seq and experimental analyses reveal the differential expression and splicing of EPDR1 and ZNF518B genes in relation to KRAS mutations in colorectal cancer cells.
Author:	Riffo-Campos, Angela L\|Castillo, Josefa\|Vallet-Sanchez, Azahara\|Ayala, Guillermo\|Cervantes, Andres\|Lopez-Rodas, Gerardo\|Franco, Luis
PMID:	27805251

2825.
Journal:	Sci Rep. 2016 Nov 9;6:36532.
Title:	Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author:	Devetzi, Marina\|Kosmidou, Vivian\|Vlassi, Margarita\|Perysinakis, Iraklis\|Aggeli, Chrysanthi\|Choreftaki, Theodosia\|Zografos, Georgios N\|Pintzas, Alexander
PMID:	27827395

2826.
Journal:	Oncotarget. 2016 Dec 6;7(49):81778-81790.
Title:	Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer.
Author:	Kwak, Yoonjin\|Koh, Jiwon\|Kim, Duck-Woo\|Kang, Sung-Bum\|Kim, Woo Ho\|Lee, Hye Seung
PMID:	27835889

2827.
Journal:	J BUON. 2016 Sept-Oct;21(5):1287-1295.
Title:	Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Author:	Cavic, Milena\|Krivokuca, Ana\|Boljevic, Ivana\|Brotto, Ksenija\|Jovanovic, Katarina\|Tanic, Miljana\|Filipovic, Lana\|Zec, Manja\|Malisic, Emina\|Jankovic, Radmila\|Radulovic, Sinisa
PMID:	27837635

2828.
Journal:	ESMO Open. 2016 Aug 4;1(4):e000079.
Title:	Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer.
Author:	Sartore-Bianchi, Andrea\|Valtorta, Emanuele\|Amatu, Alessio\|Veronese, Silvio\|Lauricella, Calogero\|Bonazzina, Erica\|Siravegna, Giulia\|Truini, Mauro\|Bardelli, Alberto\|Siena, Salvatore
PMID:	27843629

2829.
Journal:	Elife. 2016 Nov 15;5.
Title:	Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.
Author:	Verissimo, Carla S\|Overmeer, Rene M\|Ponsioen, Bas\|Drost, Jarno\|Mertens, Sander\|Verlaan-Klink, Ingrid\|Gerwen, Bastiaan van\|van der Ven, Marieke\|Wetering, Marc van de\|Egan, David A\|Bernards, Rene\|Clevers, Hans\|Bos, Johannes L\|Snippert, Hugo J
PMID:	27845624

2830.
Journal:	Sci Rep. 2016 Nov 18;6:37459.
Title:	Deregulation of the miR-16-KRAS axis promotes colorectal cancer.
Author:	You, Chaoying\|Liang, Hongwei\|Sun, Wu\|Li, Jialu\|Liu, Yanqing\|Fan, Qian\|Zhang, Haiyang\|Yue, Xin\|Li, Jing\|Chen, Xi\|Ba, Yi
PMID:	27857191

2831.
Journal:	Oncotarget. 2016 Dec 20;7(51):85349-85364.
Title:	Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer.
Author:	Kidess-Sigal, Evelyn\|Liu, Haiyan E\|Triboulet, Melanie M\|Che, James\|Ramani, Vishnu C\|Visser, Brendan C\|Poultsides, George A\|Longacre, Teri A\|Marziali, Andre\|Vysotskaia, Valentina\|Wiggin, Matthew\|Heirich, Kyra\|Hanft, Violet\|Keilholz, Ulrich\|Tinhofer, Ingebo
PMID:	27863403

2832.
Journal:	BMC Cancer. 2016 Nov 18;16(1):902.
Title:	Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
Author:	Orue, Andrea\|Chavez, Valery\|Strasberg-Rieber, Mary\|Rieber, Manuel
PMID:	27863474

2833.
Journal:	Asian Pac J Cancer Prev. 2016 Jan 9;17(9):4511-4515.
Title:	Frequency of K-RAS and N-RAS Gene Mutations in Colorectal Cancers in Southeastern Iran
Author:	Mohsen, Naseri\|Ahmadreza, Sebzari\|Fatemeh, Haghighi\|Fatemeh, Hajipoor\|Fariba, Emadian Razavi
PMID:	27880995

2834.
Journal:	Oncologist. 2016 Dec;21(12):1509-1521.
Title:	Relationship Between Metformin Use and Recurrence and Survival in Patients With Resected Stage III Colon Cancer Receiving Adjuvant Chemotherapy: Results From North Central Cancer Treatment Group N0147 (Alliance).
Author:	Singh, Preet Paul\|Shi, Qian\|Foster, Nathan R\|Grothey, Axel\|Nair, Suresh G\|Chan, Emily\|Shields, Anthony F\|Goldberg, Richard M\|Gill, Sharlene\|Kahlenberg, Morton S\|Sinicrope, Frank A\|Sargent, Daniel J\|Alberts, Steven R
PMID:	27881709

2835.
Journal:	Sci Rep. 2016 Nov 28;6:37982.
Title:	Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes.
Author:	Dou, Yongchao\|Cha, Diana J\|Franklin, Jeffrey L\|Higginbotham, James N\|Jeppesen, Dennis K\|Weaver, Alissa M\|Prasad, Nripesh\|Levy, Shawn\|Coffey, Robert J\|Patton, James G\|Zhang, Bing
PMID:	27892494

2836.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(11):1361-1365.
Title:	[New Classification for Advanced Colorectal Cancer Using CancerPlex(R)Genomic Tests].
Author:	Kameyama, Hitoshi\|Shimada, Yoshifumi\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Okuda, Shujiro\|Ling, Yiwei\|Izutsu, Hiroshi\|Kodama, Keisuke\|Nakada, Mitsutaka\|Wakai, Toshifumi
PMID:	27899776

2837.
Journal:	Oncol Lett. 2016 Nov;12(5):3356-3362.
Title:	Role of specific DNA mutations in the peripheral blood of colorectal cancer patients for the assessment of tumor stage and residual disease following tumor resection.
Author:	Norcic, Gregor\|Jelenc, Franc\|Cerkovnik, Petra\|Stegel, Vida\|Novakovic, Srdjan
PMID:	27900004

2838.
Journal:	Mol Cancer Ther. 2016 Dec;15(12):3055-3063.
Title:	STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A.
Author:	Wang, Shuo\|Darini, Cedric\|Desaubry, Laurent\|Koromilas, Antonis E
PMID:	27913706

2839.
Journal:	Int J Mol Sci. 2016 Dec 1;17(12). pii: ijms17122011.
Title:	Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells.
Author:	Pehserl, Anna-Maria\|Ress, Anna Lena\|Stanzer, Stefanie\|Resel, Margit\|Karbiener, Michael\|Stadelmeyer, Elke\|Stiegelbauer, Verena\|Gerger, Armin\|Mayr, Christian\|Scheideler, Marcel\|Hutterer, Georg C\|Bauernhofer, Thomas\|Kiesslich, Tobias\|Pichler, Martin
PMID:	27916938

2840.
Journal:	Int J Mol Sci. 2016 Dec 1;17(12). pii: ijms17122015.
Title:	High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer.
Author:	Jeantet, Marion\|Tougeron, David\|Tachon, Gaelle\|Cortes, Ulrich\|Archambaut, Celine\|Fromont, Gaelle\|Karayan-Tapon, Lucie
PMID:	27916952

2841.
Journal:	Sci Rep. 2016 Dec 7;6:38415.
Title:	Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.
Author:	Miyo, Masaaki\|Konno, Masamitsu\|Nishida, Naohiro\|Sueda, Toshinori\|Noguchi, Kozo\|Matsui, Hidetoshi\|Colvin, Hugh\|Kawamoto, Koichi\|Koseki, Jun\|Haraguchi, Naotsugu\|Nishimura, Junichi\|Hata, Taishi\|Gotoh, Noriko\|Matsuda, Fumio\|Satoh, Taroh\|Mizushima, Tsunekazu\|S
PMID:	27924922

2842.
Journal:	World J Radiol. 2016 Nov 28;8(11):880-886.
Title:	Mechanisms underlying (18)F-fluorodeoxyglucose accumulation in colorectal cancer.
Author:	Kawada, Kenji\|Iwamoto, Masayoshi\|Sakai, Yoshiharu
PMID:	27928469

2843.
Journal:	BMC Med Genet. 2016 Dec 9;17(1):94.
Title:	Pseudomyxoma peritonei of a mature ovarian teratoma caused by mismatch repair deficiency in a patient with Lynch syndrome: a case report.
Author:	Gohda, Yoshimasa\|Noguchi, Rei\|Horie, Tomoko\|Igari, Toru\|Nakamura, Harumi\|Ohta, Yasunori\|Yamaguchi, Kiyoshi\|Ikenoue, Tsuneo\|Hatakeyama, Seira\|Yusa, Nozomi\|Furukawa, Yoichi\|Yano, Hideaki
PMID:	27938333

2844.
Journal:	Medicine (Baltimore). 2016 Dec;95(50):e5649.
Title:	Coexistence of MSI with KRAS mutation is associated with worse prognosis in colorectal cancer.
Author:	Hu, Jing\|Yan, Wen-Yue\|Xie, Li\|Cheng, Lei\|Yang, Mi\|Li, Li\|Shi, Jiong\|Liu, Bao-Rui\|Qian, Xiao-Ping
PMID:	27977612

2845.
Journal:	Onco Targets Ther. 2016 Dec 7;9:7385-7395.
Title:	Association between proto-oncogene mutations and clinicopathologic characteristics and overall survival in colorectal cancer in East Azerbaijan, Iran.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Asvadi Kermani, Iraj\|Bonyadi, Morteza\|Sepehri, Bita\|Boostani, Kamal\|Azadbakht, Saleh\|Fotouhi, Nikou\|Farassati, Faris\|Dastgiri, Saeed
PMID:	27994469

2846.
Journal:	Int J Mol Sci. 2016 Dec 16;17(12). pii: ijms17122117.
Title:	Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers.
Author:	Fontanges, Quitterie\|De Mendonca, Ricardo\|Salmon, Isabelle\|Le Mercier, Marie\|D'Haene, Nicky
PMID:	27999270

2847.
Journal:	Genome Med. 2016 Dec 22;8(1):136.
Title:	Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.
Author:	Nagahashi, Masayuki\|Wakai, Toshifumi\|Shimada, Yoshifumi\|Ichikawa, Hiroshi\|Kameyama, Hitoshi\|Kobayashi, Takashi\|Sakata, Jun\|Yagi, Ryoma\|Sato, Nobuaki\|Kitagawa, Yuko\|Uetake, Hiroyuki\|Yoshida, Kazuhiro\|Oki, Eiji\|Kudo, Shin-Ei\|Izutsu, Hiroshi\|Kodama, Keisuke\|
PMID:	28007036

2848.
Journal:	Onco Targets Ther. 2016 Dec 13;9:7503-7513.
Title:	Early detection of poor outcome in patients with metastatic colorectal cancer: tumor kinetics evaluated by circulating tumor cells.
Author:	Souza E Silva, Virgilio\|Chinen, Ludmilla Thome Domingos\|Abdallah, Emne A\|Damascena, Aline\|Paludo, Jociana\|Chojniak, Rubens\|Dettino, Aldo Lourenco Abbade\|de Mello, Celso Abdon Lopes\|Alves, Vanessa S\|Fanelli, Marcello F
PMID:	28008271

2849.
Journal:	Curr Oncol. 2016 Dec;23(6):e571-e575.
Title:	Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author:	Sheffield, B S\|Tessier-Cloutier, B\|Li-Chang, H\|Shen, Y\|Pleasance, E\|Kasaian, K\|Li, Y\|Jones, S J M\|Lim, H J\|Renouf, D J\|Huntsman, D G\|Yip, S\|Laskin, J\|Marra, M\|Schaeffer, D F
PMID:	28050146

2850.
Journal:	J Gastrointest Oncol. 2016 Dec;7(6):882-902.
Title:	Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.
Author:	Al-Shamsi, Humaid O\|Jones, Jeremy\|Fahmawi, Yazan\|Dahbour, Ibrahim\|Tabash, Aziz\|Abdel-Wahab, Reham\|Abousamra, Ahmed O S\|Shaw, Kenna R\|Xiao, Lianchun\|Hassan, Manal M\|Kipp, Benjamin R\|Kopetz, Scott\|Soliman, Amr S\|McWilliams, Robert R\|Wolff, Robert A
PMID:	28078112

2851.
Journal:	World J Gastroenterol. 2016 Dec 28;22(48):10680-10686.
Title:	Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.
Author:	Ghiringhelli, Francois\|Richard, Corentin\|Chevrier, Sandy\|Vegran, Frederique\|Boidot, Romain
PMID:	28082821

2852.
Journal:	Oncol Lett. 2016 Dec;12(6):4427-4434.
Title:	Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation.
Author:	Huang, Chi-Jung\|Huang, Shih-Hung\|Chien, Chih-Cheng\|Lee, Henry Hsin-Chung\|Yang, Shung-Haur\|Chang, Chun-Chao\|Lee, Chia-Long
PMID:	28101205

2853.
Journal:	Oncol Lett. 2016 Dec;12(6):4589-4597.
Title:	miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer.
Author:	Zhang, Nan\|Lu, Canrong\|Chen, Lin
PMID:	28105166

2854.
Journal:	Oncol Lett. 2016 Dec;12(6):4850-4856.
Title:	Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity.
Author:	Kim, Chul Jang\|Tambe, Yukihiro\|Mukaisho, Ken-Ichi\|Sugihara, Hiroyuki\|Kawauchi, Akihiro\|Inoue, Hirokazu
PMID:	28105192

2855.
Journal:	Oncoimmunology. 2016 Nov 29;5(12):e1254313.
Title:	CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.
Author:	D'Alterio, Crescenzo\|Nasti, Guglielmo\|Polimeno, Marianeve\|Ottaiano, Alessandro\|Conson, Manuel\|Circelli, Luisa\|Botti, Giovanni\|Scognamiglio, Giosue\|Santagata, Sara\|De Divitiis, Chiara\|Nappi, Anna\|Napolitano, Maria\|Tatangelo, Fabiana\|Pacelli, Roberto\|Izzo,
PMID:	28123896

2856.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2280-2282.
Title:	[A Systematic Analysis of Oncogene and Tumor Suppressor Genes for Panitumumab-Resistant Rectal Cancer with Wild RAS Gene - A Case Report].
Author:	Tajima, Yosuke\|Shimada, Yoshifumi\|Yagi, Ryoma\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Miura, Kohei\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133295

2857.
Journal:	Gan To Kagaku Ryoho. 2016 Nov;43(12):2307-2309.
Title:	[A Case of Metastatic Colorectal Cancer with HER2 Overexpression/Amplification].
Author:	Matsumoto, Akio\|Shimada, Yoshifumi\|Yagi, Ryoma\|Miura, Kohei\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Kameyama, Hitoshi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Ichikawa, Hiroshi\|Sakata, Jun\|Kobayashi, Takashi\|Wakai, Toshifumi
PMID:	28133304

2858.
Journal:	J Cancer Res Ther. 2016 Oct-Dec;12(4):1272-1277.
Title:	Modified mismatch polymerase chain reaction-restriction fragment length polymorphism detected mutations in codon 12 and 13 of exon 2 of K-ras gene in colorectal cancer patients and its association with liver metastases: Data from a South Asian country.
Author:	Faleel, Fathima Dhilhani Mohamed\|Zoysa, M I M De\|Lokuhetti, M D S\|Gunawardena, Y I N S\|Chandrasekharan, Vishvanath Naduviladath\|Dassanayake, Ranil Samantha
PMID:	28169239

2859.
Journal:	J Cancer Res Ther. 2016 Dec;12(Supplement):C191-C198.
Title:	Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta-analysis.
Author:	Lin, Li\|Chen, Guang-Yong\|Xu, Chun-Wei\|Wang, Hai-Yan\|Wu, Yong-Fang\|Fang, Mei-Yu
PMID:	28230016

2860.
Journal:	J Cancer Res Ther. 2016 Dec;12(Supplement):C205-C211.
Title:	The significance of transarterial chemoembolization combined with systemic chemotherapy for patients with KRAS wild-type unresectable metachronous colorectal carcinoma with liver metastases.
Author:	Yu, Qiming\|Zhang, Lusha\|Fan, Sunfu\|Huang, Ling\|Wang, Xinbao\|Xindun, Cai
PMID:	28230018

2861.
Journal:	Acta Med Litu. 2016;23(1):24-34.
Title:	Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience.
Author:	Baltruskeviciene, Edita\|Mickys, Ugnius\|Zvirblis, Tadas\|Stulpinas, Rokas\|Pipiriene Zelviene, Terese\|Aleknavicius, Eduardas
PMID:	28356789

2862.
Journal:	ESMO Open. 2017 Feb 20;1(6):e000086.
Title:	Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial.
Author:	Martinelli, E\|Cardone, C\|Troiani, T\|Normanno, N\|Pisconti, S\|Sforza, V\|Bordonaro, A R\|Rachiglio, A M\|Lambiase, M\|Latiano, T P\|Modoni, G\|Cordio, S\|Giuliani, F\|Biglietto, M\|Montesarchio, V\|Barone, C\|Tonini, G\|Cinieri, S\|Febbraro, A\|Rizzi, D\|De Vita, F\|Orditu
PMID:	28848656

2863.
Journal:	Mol Oncol. 2016 Dec;10(10):1575-1584.
Title:	Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases.
Author:	Beije, Nick\|Helmijr, Jean C\|Weerts, Marjolein J A\|Beaufort, Corine M\|Wiggin, Matthew\|Marziali, Andre\|Verhoef, Cornelis\|Sleijfer, Stefan\|Jansen, Maurice P H M\|Martens, John W M
PMID:	28949453

2864.
Journal:	React Oxyg Species (Apex). 2016 Mar;1(2):141-156.
Title:	Vitamin C, a Multi-Tasking Molecule, Finds a Molecular Target in Killing Cancer Cells.
Author:	Li, Robert
PMID:	29780883

2865.
Journal:	Klin Onkol. Winter 2016;29(6):419-427.
Title:	[Molecular Pathogenesis of Colorectal Cancer].
Author:	Kral, J\|Slyskova, J\|Vodicka, P\|Spicak, J
PMID:	27951718

2866.
Journal:	Am J Clin Oncol. 2017 Jun;40(3):274-276.
Title:	The Frequency and Type of K-RAS Mutations in Mexican Patients With Colorectal Cancer: A National Study.
Author:	Cardenas-Ramos, Susana G\|Alcazar-Gonzalez, Gregorio\|Reyes-Cortes, Luisa M\|Torres-Grimaldo, Abdiel A\|Calderon-Garciduenas, Ana L\|Morales-Casas, Jose\|Flores-Sanchez, Patricia\|De Leon-Escobedo, Raul\|Gomez-Diaz, Antonio\|Moreno-Bringas, Carmen\|Sanchez-Guillen,
PMID:	25333735

2867.
Journal:	Am J Clin Oncol. 2017 Oct;40(5):498-506.
Title:	Factors Associated With Guideline-recommended KRAS Testing in Colorectal Cancer Patients: A Population-based Study.
Author:	Charlton, Mary E\|Karlitz, Jordan J\|Schlichting, Jennifer A\|Chen, Vivien W\|Lynch, Charles F
PMID:	25844824

2868.
Journal:	Asia Pac J Clin Oncol. 2017 Apr;13(2):e132-e137.
Title:	Phase II study of cetuximab with irinotecan for KRAS wild-type colorectal cancer in Japanese patients.
Author:	Terazawa, Tetsuji\|Nishitani, Hitoshi\|Kato, Ken\|Hashimoto, Hironobu\|Akiyoshi, Kohei\|Ito, Yuriko\|Nakamoto, Akihiro\|Iwasa, Satoru\|Nakajima, Takako Eguchi\|Hamaguchi, Tetsuya\|Yamada, Yasuhide\|Shimada, Yasuhiro
PMID:	26245851

2869.
Journal:	Oncotarget. 2017 Apr 4;8(14):22414-22432.
Title:	Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.
Author:	Zou, Zheng-Zhi\|Nie, Pei-Pei\|Li, Ya-Wei\|Hou, Ben-Xin\|Rui-Li\|Shi, Xin-Peng\|Ma, Zhao-Kui\|Han, Bao-Wei\|Luo, Xiao-Yong
PMID:	26461472

2870.
Journal:	Gut. 2017 Jan;66(1):97-106.
Title:	Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Author:	Bettington, Mark\|Walker, Neal\|Rosty, Christophe\|Brown, Ian\|Clouston, Andrew\|McKeone, Diane\|Pearson, Sally-Ann\|Leggett, Barbara\|Whitehall, Vicki
PMID:	26475632

2871.
Journal:	Oncotarget. 2017 Feb 21;8(8):13611-13619.
Title:	Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA.
Author:	Del Re, Marzia\|Tiseo, Marcello\|Bordi, Paola\|D'Incecco, Armida\|Camerini, Andrea\|Petrini, Iacopo\|Lucchesi, Maurizio\|Inno, Alessandro\|Spada, Daniele\|Vasile, Enrico\|Citi, Valentina\|Malpeli, Giorgio\|Testa, Enrica\|Gori, Stefania\|Falcone, Alfredo\|Amoroso, Domeni
PMID:	26799287

2872.
Journal:	Appl Immunohistochem Mol Morphol. 2017 Aug;25(7):475-480.
Title:	NRASQ61R Mutation-specific Immunohistochemistry is Highly Specific for Either NRASQ61R or KRASQ61R Mutation in Colorectal Carcinoma.
Author:	Turchini, John\|Andrici, Juliana\|Sioson, Loretta\|Clarkson, Adele\|Watson, Nicole\|Toon, Christopher W\|Shepherd, Phillip\|Ng, Daniel\|Dixon-McIver, Amanda\|Oei, Paul\|Gill, Anthony J
PMID:	26862952

2873.
Journal:	Mol Carcinog. 2017 Jan;56(1):106-117.
Title:	Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: A subset of colorectal cancer patients with FGF9 upregulation may be resistant to anti-EGFR therapies.
Author:	Mizukami, Takuro\|Togashi, Yosuke\|Naruki, Saeko\|Banno, Eri\|Terashima, Masato\|de Velasco, Marco A\|Sakai, Kazuko\|Yoneshige, Azusa\|Hayashi, Hidetoshi\|Fujita, Yoshihiko\|Tomida, Shuta\|Nakajima, Takako Eguchi\|Fujino, Takashi\|Boku, Narikazu\|Ito, Akihiko\|Nakagawa,
PMID:	26916220

2874.
Journal:	Gut. 2017 Aug;66(8):1463-1473.
Title:	Tumour CD274 (PD-L1) expression and T cells in colorectal cancer.
Author:	Masugi, Yohei\|Nishihara, Reiko\|Yang, Juhong\|Mima, Kosuke\|da Silva, Annacarolina\|Shi, Yan\|Inamura, Kentaro\|Cao, Yin\|Song, Mingyang\|Nowak, Jonathan A\|Liao, Xiaoyun\|Nosho, Katsuhiko\|Chan, Andrew T\|Giannakis, Marios\|Bass, Adam J\|Hodi, F Stephen\|Freeman, Gordo
PMID:	27196573

2875.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):104-115.
Title:	BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.
Author:	Barras, David\|Missiaglia, Edoardo\|Wirapati, Pratyaksha\|Sieber, Oliver M\|Jorissen, Robert N\|Love, Chris\|Molloy, Peter L\|Jones, Ian T\|McLaughlin, Stephen\|Gibbs, Peter\|Guinney, Justin\|Simon, Iris M\|Roth, Arnaud D\|Bosman, Fred T\|Tejpar, Sabine\|Delorenzi, Maur
PMID:	27354468

2876.
Journal:	Cancer Res Treat. 2017 Jan;49(1):161-167.
Title:	Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.
Author:	Kim, Kyu-Pyo\|Kim, Jeong-Eun\|Hong, Yong Sang\|Ahn, Sung-Min\|Chun, Sung Min\|Hong, Seung-Mo\|Jang, Se Jin\|Yu, Chang Sik\|Kim, Jin Cheon\|Kim, Tae Won
PMID:	27384156

2877.
Journal:	Oncogene. 2017 Feb 9;36(6):787-796.
Title:	FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
Author:	Tong, J\|Tan, S\|Zou, F\|Yu, J\|Zhang, L
PMID:	27399335

2878.
Journal:	Clin Cancer Res. 2017 Jan 1;23(1):159-170.
Title:	Dysregulation of EGFR Pathway in EphA2 Cell Subpopulation Significantly Associates with Poor Prognosis in Colorectal Cancer.
Author:	De Robertis, Mariangela\|Loiacono, Luisa\|Fusilli, Caterina\|Poeta, Maria Luana\|Mazza, Tommaso\|Sanchez, Massimo\|Marchionni, Luigi\|Signori, Emanuela\|Lamorte, Giuseppe\|Vescovi, Angelo Luigi\|Garcia-Foncillas, Jesus\|Fazio, Vito Michele
PMID:	27401248

2879.
Journal:	Gut. 2017 Jun;66(6):1095-1105.
Title:	RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Author:	Hilkens, John\|Timmer, Nikki C\|Boer, Mandy\|Ikink, Gerjon J\|Schewe, Matthias\|Sacchetti, Andrea\|Koppens, Martijn A J\|Song, Ji-Ying\|Bakker, Elvira R M
PMID:	27511199

2880.
Journal:	Oncotarget. 2017 Jun 20;8(25):40169-40180.
Title:	Downregulation of microRNA-199b predicts unfavorable prognosis and emerges as a novel therapeutic target which contributes to PP2A inhibition in metastatic colorectal cancer.
Author:	Cristobal, Ion\|Carames, Cristina\|Rincon, Raul\|Manso, Rebeca\|Madoz-Gurpide, Juan\|Torrejon, Blanca\|Gonzalez-Alonso, Paula\|Rojo, Federico\|Garcia-Foncillas, Jesus
PMID:	27517624

2881.
Journal:	Histopathology. 2017 Jan;70(2):223-231.
Title:	Micropapillary colorectal carcinoma: clinical, pathological and molecular properties, including evidence of epithelial-mesenchymal transition.
Author:	Gonzalez, Raul S\|Huh, Won Jae\|Cates, Justin M M\|Washington, Kay\|Beauchamp, R Daniel\|Coffey, Robert J\|Shi, Chanjuan
PMID:	27560620

2882.
Journal:	Int J Surg Pathol. 2017 Apr;25(2):108-117.
Title:	Mucinous and Signet Ring Cell Differentiation Affect Patterns of Metastasis in Colorectal Carcinoma and Influence Survival.
Author:	Kermanshahi, Taher Reza\|Magge, Deepa\|Choudry, Haroon\|Ramalingam, Leksmi\|Zhu, Benjamin\|Pingpank, James\|Ahrendt, Steven\|Holtzman, Matthew\|Zeh, Herbert\|Bartlett, David\|Zureikat, Amer\|Pai, Reetesh K
PMID:	27571790

2883.
Journal:	Semin Cell Dev Biol. 2017 Apr;64:107-115.
Title:	Colorectal cancer heterogeneity and targeted therapy: Clinical implications, challenges and solutions for treatment resistance.
Author:	Zhai, Zhenhua\|Yu, Xiaohui\|Yang, Bin\|Zhang, Yunjing\|Zhang, Long\|Li, Xiaoli\|Sun, Hongzhi
PMID:	27578007

2884.
Journal:	Future Oncol. 2017 Jan;13(2):135-144.
Title:	Comparison of the molecular profile of brain metastases from colorectal cancer and corresponding primary tumors.
Author:	Aprile, Giuseppe\|Casagrande, Mariaelena\|De Maglio, Giovanna\|Fontanella, Caterina\|Rihawi, Karim\|Bonotto, Marta\|Pisa, Federica E\|Tuniz, Francesco\|Pizzolitto, Stefano\|Fasola, Gianpiero
PMID:	27578453

2885.
Journal:	Semin Cell Dev Biol. 2017 Apr;64:58-64.
Title:	Gene heterogeneity in metastasis of colorectal cancer to the lung.
Author:	Hou, Jiayun\|Zhang, Yong\|Zhu, Zhitu
PMID:	27590223

2886.
Journal:	Abdom Radiol (NY). 2017 Feb;42(2):451-459.
Title:	Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90.
Author:	Magnetta, Michael J\|Ghodadra, Anish\|Lahti, Steven J\|Xing, Minzhi\|Zhang, Di\|Kim, Hyun S
PMID:	27600383

2887.
Journal:	Gut. 2017 Dec;66(12):2132-2140.
Title:	Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.
Author:	Sievers, Chelsie K\|Zou, Luli S\|Pickhardt, Perry J\|Matkowskyj, Kristina A\|Albrecht, Dawn M\|Clipson, Linda\|Bacher, Jeffery W\|Pooler, B Dustin\|Moawad, Fouad J\|Cash, Brooks D\|Reichelderfer, Mark\|Vo, Tien N\|Newton, Michael A\|Larget, Bret R\|Halberg, Richard B
PMID:	27609830

2888.
Journal:	Ann Surg Oncol. 2017 Feb;24(2):546-553.
Title:	The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer.
Author:	Kataoka, Masato\|Kanda, Mitsuro\|Ishigure, Kiyoshi\|Matsuoka, Hiroshi\|Sato, Yusuke\|Takahashi, Takao\|Tanaka, Chihiro\|Deguchi, Tomohiro\|Shibata, Yoshihisa\|Sato, Mikinori\|Inagaki, Hitoshi\|Matsui, Takanori\|Kondo, Akinobu\|Takano, Nao\|Tanaka, Haruyoshi\|Sakamoto, J
PMID:	27638675

2889.
Journal:	Gut. 2017 Jun;66(6):1106-1115.
Title:	Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer.
Author:	Borovski, Tijana\|Vellinga, Thomas T\|Laoukili, Jamila\|Santo, Evan E\|Fatrai, Szabolcs\|van Schelven, Susanne\|Verheem, Andre\|Marvin, Dieuwke L\|Ubink, Inge\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	27670374

2890.
Journal:	Clin Colorectal Cancer. 2017 Sep;16(3):e211-e220.
Title:	Radiosensitivity of Colon and Rectal Lung Oligometastasis Treated With Stereotactic Ablative Radiotherapy.
Author:	Kinj, Remy\|Bondiau, Pierre-Yves\|Francois, Eric\|Gerard, Jean-Pierre\|Naghavi, Arash O\|Leysalle, Axel\|Chamorey, Emmanuel\|Evesque, Ludovic\|Padovani, Bernard\|Ianessi, Antoine\|Benezery, Karen\|Doyen, Jerome
PMID:	27670890

2891.
Journal:	Int J Cancer. 2017 Jan 15;140(2):431-439.
Title:	Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial.
Author:	Sclafani, Francesco\|Kim, Tae Y\|Cunningham, David\|Kim, Tae W\|Tabernero, Josep\|Schmoll, Hans J\|Roh, Jae K\|Kim, Sun Y\|Park, Young S\|Guren, Tormod K\|Hawkes, Eliza\|Clarke, Stephen J\|Ferry, David\|Frodin, Jan-Erik\|Ayers, Mark\|Nebozhyn, Michael\|Peckitt, Clare\|Lob
PMID:	27681944

2892.
Journal:	Food Chem Toxicol. 2017 Aug;106(Pt B):583-594.
Title:	Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens.
Author:	Fahrer, Jorg\|Kaina, Bernd
PMID:	27693244

2893.
Journal:	Pathol Oncol Res. 2017 Apr;23(2):417-423.
Title:	Mutant KRAS Status Is Associated with Increased KRAS Copy Number Imbalance: a Potential Mechanism of Molecular Heterogeneity.
Author:	Docs, Otto\|Hegyi, Katalin\|Mokanszky, Attila\|Monusne, Aniko\|Beke, Livia\|Andras, Csilla\|Bedekovics, Judit\|Mehes, Gabor
PMID:	27743339

2894.
Journal:	J Natl Cancer Inst. 2016 Oct 22;109(2). pii: djw209.
Title:	Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
Author:	Picco, Gabriele\|Petti, Consalvo\|Sassi, Francesco\|Grillone, Katia\|Migliardi, Giorgia\|Rossi, Teresa\|Isella, Claudio\|Di Nicolantonio, Federica\|Sarotto, Ivana\|Sapino, Anna\|Bardelli, Alberto\|Trusolino, Livio\|Bertotti, Andrea\|Medico, Enzo
PMID:	27771609

2895.
Journal:	Cancer Lett. 2017 Jan 28;385:160-167.
Title:	Baseline MAPK signaling activity confers intrinsic radioresistance to KRAS-mutant colorectal carcinoma cells by rapid upregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K).
Author:	Eder, Stefan\|Arndt, Annette\|Lamkowski, Andreas\|Daskalaki, Wassiliki\|Rump, Alexis\|Priller, Markus\|Genze, Felicitas\|Wardelmann, Eva\|Port, Matthias\|Steinestel, Konrad
PMID:	27793696

2896.
Journal:	Clin Cancer Res. 2017 Jun 1;23(11):2742-2749.
Title:	BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.
Author:	Summers, Matthew G\|Smith, Christopher G\|Maughan, Timothy S\|Kaplan, Richard\|Escott-Price, Valentina\|Cheadle, Jeremy P
PMID:	27815357

2897.
Journal:	Eur J Surg Oncol. 2017 Feb;43(2):311-321.
Title:	Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
Author:	Ghanipour, L\|Jirstrom, K\|Sundstrom, M\|Glimelius, B\|Birgisson, H
PMID:	27836416

2898.
Journal:	Cancer. 2017 Apr 1;123(7):1134-1143.
Title:	Clinical and genetic determinants of ovarian metastases from colorectal cancer.
Author:	Ganesh, Karuna\|Shah, Ronak H\|Vakiani, Efsevia\|Nash, Garrett M\|Skottowe, Hugh P\|Yaeger, Rona\|Cercek, Andrea\|Lincoln, Anne\|Tran, Christina\|Segal, Neil H\|Reidy, Diane L\|Varghese, Anna\|Epstein, Andrew S\|Sonoda, Yukio\|Chi, Dennis\|Guillem, Jose\|Temple, Larissa\|
PMID:	27875625

2899.
Journal:	Int J Cancer. 2017 Feb 15;140(4):922-929.
Title:	EGFR gene copy number predicts response to anti-EGFR treatment in RAS wild type and RAS/BRAF/PIK3CA wild type metastatic colorectal cancer.
Author:	Algars, Annika\|Sundstrom, Jari\|Lintunen, Minnamaija\|Jokilehto, Terhi\|Kytola, Soili\|Kaare, Milja\|Vainionpaa, Reetta\|Orpana, Arto\|Osterlund, Pia\|Ristimaki, Ari\|Carpen, Olli\|Ristamaki, Raija
PMID:	27879995

2900.
Journal:	Pharmacogenomics J. 2017 Dec;17(6):535-542.
Title:	Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.
Author:	Morgen, E K\|Lenz, H-J\|Jonker, D J\|Tu, D\|Milano, G\|Graziano, F\|Zalcberg, J\|Karapetis, C S\|Dobrovic, A\|O'Callaghan, C J\|Liu, G
PMID:	27897268

2901.
Journal:	Oncotarget. 2017 Jan 10;8(2):2514-2524.
Title:	KRAS exon 2 codon 13 mutation is associated with a better prognosis than codon 12 mutation following lung metastasectomy in colorectal cancer.
Author:	Renaud, Stephane\|Guerrera, Francesco\|Seitlinger, Joseph\|Costardi, Lorena\|Schaeffer, Mickael\|Romain, Benoit\|Mossetti, Claudio\|Claire-Voegeli, Anne\|Filosso, Pier Luigi\|Legrain, Michele\|Ruffini, Enrico\|Falcoz, Pierre-Emmanuel\|Oliaro, Alberto\|Massard, Gilbert
PMID:	27911859

2902.
Journal:	Oncology. 2017;92(2):75-86.
Title:	Clinicopathological Features and Predictive Factors for Colorectal Cancer Outcome in the Kingdom of Saudi Arabia.
Author:	Aldiab, Abdurrahman\|Al Khayal, Khayal A\|Al Obaid, Omar A\|Alsheikh, Ahmed\|Alsaleh, Khalid\|Shahid, Mohamed\|Alkharji, Hana
PMID:	27915339

2903.
Journal:	J Comput Biol. 2017 Jun;24(6):603-615.
Title:	pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Progression Dynamics.
Author:	Cristea, Simona\|Kuipers, Jack\|Beerenwinkel, Niko
PMID:	27936934

2904.
Journal:	Int J Cancer. 2017 Apr 1;140(7):1485-1493.
Title:	Lifetime alcohol intake is associated with an increased risk of KRAS+ and BRAF-/KRAS- but not BRAF+ colorectal cancer.
Author:	Jayasekara, Harindra\|MacInnis, Robert J\|Williamson, Elizabeth J\|Hodge, Allison M\|Clendenning, Mark\|Rosty, Christophe\|Walters, Rhiannon\|Room, Robin\|Southey, Melissa C\|Jenkins, Mark A\|Milne, Roger L\|Hopper, John L\|Giles, Graham G\|Buchanan, Daniel D\|English,
PMID:	27943267

2905.
Journal:	Oncotarget. 2017 Jan 10;8(2):3206-3225.
Title:	KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies.
Author:	Wen, Qing\|Dunne, Philip D\|O'Reilly, Paul G\|Li, Gerald\|Bjourson, Anthony J\|McArt, Darragh G\|Hamilton, Peter W\|Zhang, Shu-Dong
PMID:	27965461

2906.
Journal:	Clin Colorectal Cancer. 2017 Sep;16(3):e191-e198.
Title:	Perioperative Triplet Chemotherapy and Cetuximab in Patients With RAS Wild Type High Recurrence Risk or Borderline Resectable Colorectal Cancer Liver Metastases.
Author:	Pietrantonio, Filippo\|Di Bartolomeo, Maria\|Cotsoglou, Christian\|Mennitto, Alessia\|Berenato, Rosa\|Morano, Federica\|Coppa, Jorgelina\|Perrone, Federica\|Iacovelli, Roberto\|Milione, Massimo\|Alessi, Alessandra\|Vaiani, Marta\|Bossi, Ilaria\|Ricchini, Francesca\|Sco
PMID:	27979717

2907.
Journal:	J Theor Biol. 2017 Feb 21;415:70-83.
Title:	Exosomal microRNA concentrations in colorectal cancer: A mathematical model.
Author:	Lai, Xiulan\|Friedman, Avner
PMID:	27993628

2908.
Journal:	Oncotarget. 2017 Feb 7;8(6):9251-9266.
Title:	LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.
Author:	Vakana, Eliza\|Pratt, Susan\|Blosser, Wayne\|Dowless, Michele\|Simpson, Nicholas\|Yuan, Xiu-Juan\|Jaken, Susan\|Manro, Jason\|Stephens, Jennifer\|Zhang, Youyan\|Huber, Lysiane\|Peng, Sheng-Bin\|Stancato, Louis F
PMID:	27999210

2909.
Journal:	Int J Oncol. 2017 Feb;50(2):487-496.
Title:	Identification of microRNA-487b as a negative regulator of liver metastasis by regulation of KRAS in colorectal cancer.
Author:	Hata, Tsuyoshi\|Mokutani, Yukako\|Takahashi, Hidekazu\|Inoue, Akira\|Munakata, Koji\|Nagata, Kazuya\|Haraguchi, Naotsugu\|Nishimura, Junichi\|Hata, Taishi\|Matsuda, Chu\|Murata, Kohei\|Mizushima, Tsunekazu\|Doki, Yuichiro\|Mori, Masaki\|Yamamoto, Hirofumi
PMID:	28000854

2910.
Journal:	Oncol Rep. 2017 Feb;37(2):785-792.
Title:	High concordance rate of KRAS/BRAF mutations and MSI-H between primary colorectal cancer and corresponding metastases.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28000889

2911.
Journal:	Oncotarget. 2017 Jan 31;8(5):7852-7866.
Title:	Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Author:	Ashktorab, Hassan\|Mokarram, Pooneh\|Azimi, Hamed\|Olumi, Hasti\|Varma, Sudhir\|Nickerson, Michael L\|Brim, Hassan
PMID:	28002797

2912.
Journal:	Oncotarget. 2017 Jan 17;8(3):5003-5015.
Title:	Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells.
Author:	Song, Qiaoling\|Sun, Xiaoxiao\|Guo, Hui\|Yu, Qiang
PMID:	28002807

2913.
Journal:	Oncol Rep. 2017 Jan;37(1):57-65.
Title:	Yttrium-90 radioembolization for colorectal cancer liver metastases in KRAS wild-type and mutant patients: Clinical and ccfDNA studies.
Author:	Janowski, E\|Timofeeva, O\|Chasovskikh, S\|Goldberg, M\|Kim, A\|Banovac, F\|Pang, D\|Dritschilo, A\|Unger, K
PMID:	28004119

2914.
Journal:	JAMA Oncol. 2017 Apr 1;3(4):472-480.
Title:	Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers : A Secondary Analysis of 2 Randomized Clinical Trials.
Author:	Sinicrope, Frank A\|Shi, Qian\|Allegra, Carmen J\|Smyrk, Thomas C\|Thibodeau, Stephen N\|Goldberg, Richard M\|Meyers, Jeffrey P\|Pogue-Geile, Kay L\|Yothers, Greg\|Sargent, Daniel J\|Alberts, Steven R
PMID:	28006055

2915.
Journal:	Crit Rev Oncol Hematol. 2017 Jan;109:9-19.
Title:	Clinical relevance of colorectal cancer molecular subtypes.
Author:	Rodriguez-Salas, Nuria\|Dominguez, Gema\|Barderas, Rodrigo\|Mendiola, Marta\|Garcia-Albeniz, Xabier\|Maurel, Juan\|Batlle, Jaime Feliu
PMID:	28010901

2916.
Journal:	Anticancer Res. 2017 Jan;37(1):239-247.
Title:	Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor.
Author:	Fujiyoshi, Kenji\|Yamamoto, Gou\|Takenoya, Takashi\|Takahashi, Akemi\|Arai, Yoshiko\|Yamada, Mina\|Kakuta, Miho\|Yamaguchi, Kensei\|Akagi, Yoshito\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Akagi, Kiwamu
PMID:	28011498

2917.
Journal:	Hum Pathol. 2017 Apr;62:91-98.
Title:	Analysis of KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer.
Author:	Reggiani Bonetti, Luca\|Barresi, Valeria\|Bettelli, Stefania\|Caprera, Cecilia\|Manfredini, Samantha\|Maiorana, Antonio
PMID:	28025078

2918.
Journal:	Pathol Oncol Res. 2017 Jul;23(3):673-677.
Title:	EGFR Gene Amplification and KRAS Mutation Predict Response to Combination Targeted Therapy in Metastatic Colorectal Cancer.
Author:	Khan, Sajid A\|Zeng, Zhaoshi\|Shia, Jinru\|Paty, Philip B
PMID:	28025786

2919.
Journal:	Ann Oncol. 2017 Apr 1;28(4):824-830.
Title:	Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients.
Author:	Taieb, J\|Balogoun, R\|Le Malicot, K\|Tabernero, J\|Mini, E\|Folprecht, G\|Van Laethem, J-L\|Emile, J-F\|Mulot, C\|Fratte, S\|Levache, C-B\|Saban-Roche, L\|Thaler, J\|Petersen, L N\|Bridgewater, J\|Perkins, G\|Lepage, C\|Van Cutsem, E\|Zaanan, A\|Laurent-Puig, P
PMID:	28031175

2920.
Journal:	J Natl Cancer Inst. 2016 Dec 31;109(5). pii: 2760215.
Title:	Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer.
Author:	Taieb, Julien\|Le Malicot, Karine\|Shi, Qian\|Penault-Llorca, Frederique\|Bouche, Olivier\|Tabernero, Josep\|Mini, Enrico\|Goldberg, Richard M\|Folprecht, Gunnar\|Luc Van Laethem, Jean\|Sargent, Daniel J\|Alberts, Steven R\|Emile, Jean Francois\|Laurent Puig, Pierre\|S
PMID:	28040692

2921.
Journal:	J Natl Compr Canc Netw. 2017 Jan;15(1):3-8.
Title:	Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.
Author:	Parikh, Aparna\|Atreya, Chloe\|Korn, W Michael\|Venook, Alan P
PMID:	28040715

2922.
Journal:	Future Oncol. 2017 Apr;13(9):777-786.
Title:	Phase II trial of capecitabine plus erlotinib versus capecitabine alone in patients with advanced colorectal cancer.
Author:	Vincent, Mark D\|Breadner, Daniel\|Soulieres, Denis\|Kerr, Ian G\|Sanatani, Michael\|Kocha, Walter\|Klimo, Peter\|MacKenzie, Mary J\|O'Connell, Anne\|Whiston, Frances\|Malpage, Anne S\|Stitt, Larry\|Welch, Stephen A
PMID:	28045335

2923.
Journal:	Pathol Oncol Res. 2017 Oct;23(4):737-744.
Title:	Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.
Author:	Hosoya, Kazuhisa\|Matsusaka, Satoshi\|Kashiwada, Tomomi\|Suzuki, Koichi\|Ureshino, Norio\|Sato, Akemi\|Miki, Yoshio\|Kitera, Kazuki\|Hirai, Mitsuharu\|Hatake, Kiyohiko\|Kimura, Shinya\|Sueoka-Aragane, Naoko
PMID:	28058585

2924.
Journal:	Future Oncol. 2017 Apr;13(10):919-934.
Title:	Translating genomic profiling to gastrointestinal cancer treatment.
Author:	Harada, Kazuto\|Mizrak Kaya, Dilsa\|Shimodaira, Yusuke\|Song, Shumei\|Baba, Hideo\|Ajani, Jaffer A
PMID:	28067073

2925.
Journal:	BMC Cancer. 2017 Jan 9;17(1):38.
Title:	Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients.
Author:	Nakayama, Izuma\|Shinozaki, Eiji\|Matsushima, Tomohiro\|Wakatsuki, Takeru\|Ogura, Mariko\|Ichimura, Takashi\|Ozaka, Masato\|Takahari, Daisuke\|Suenaga, Mitsukuni\|Chin, Keisho\|Mizunuma, Nobuyuki\|Yamaguchi, Kensei
PMID:	28068936

2926.
Journal:	Med Oncol. 2017 Feb;34(2):26.
Title:	KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma.
Author:	Cicenas, Jonas\|Tamosaitis, Linas\|Kvederaviciute, Kotryna\|Tarvydas, Ricardas\|Staniute, Gintare\|Kalyan, Karthik\|Meskinyte-Kausiliene, Edita\|Stankevicius, Vaidotas\|Valius, Mindaugas
PMID:	28074351

2927.
Journal:	Oncotarget. 2017 Mar 28;8(13):22175-22186.
Title:	KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis.
Author:	Du, Lijun\|Kim, John J\|Shen, Jinhua\|Chen, Binrui\|Dai, Ning
PMID:	28077799

2928.
Journal:	Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2381-2385.
Title:	Conformational SERS Classification of K-Ras Point Mutations for Cancer Diagnostics.
Author:	Morla-Folch, Judit\|Gisbert-Quilis, Patricia\|Masetti, Matteo\|Garcia-Rico, Eduardo\|Alvarez-Puebla, Ramon A\|Guerrini, Luca
PMID:	28079954

2929.
Journal:	Cancer Sci. 2017 Mar;108(3):427-434.
Title:	Molecular subtypes of colorectal cancers determined by PCR-based analysis.
Author:	Sugai, Tamotsu\|Eizuka, Makoto\|Takahashi, Yayoi\|Fukagawa, Tomoyuki\|Habano, Wataru\|Yamamoto, Eiichiro\|Akasaka, Risaburo\|Otuska, Kouki\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	28083970

2930.
Journal:	Bull Exp Biol Med. 2017 Jan;162(3):375-378.
Title:	Detection of Rare Mutations by Routine Analysis of KRAS, NRAS, and BRAF Oncogenes.
Author:	Mikhailenko, D S\|Efremov, G D\|Safronova, N Yu\|Strelnikov, V V\|Alekseev, B Ya
PMID:	28091917

2931.
Journal:	J Oncol Pract. 2017 Mar;13(3):e185-e196.
Title:	Medical Oncologists' Experiences in Using Genomic Testing for Lung and Colorectal Cancer Care.
Author:	Gray, Stacy W\|Kim, Benjamin\|Sholl, Lynette\|Cronin, Angel\|Parikh, Aparna R\|Klabunde, Carrie N\|Kahn, Katherine L\|Haggstrom, David A\|Keating, Nancy L
PMID:	28095174

2932.
Journal:	World J Surg. 2017 May;41(5):1375-1383.
Title:	Genetic and Epigenetic Intra-tumour Heterogeneity in Colorectal Cancer.
Author:	Jones, Huw Geraint\|Jenkins, Gareth\|Williams, Namor\|Griffiths, Paul\|Chambers, Phil\|Beynon, John\|Harris, Dean
PMID:	28097409

2933.
Journal:	PLoS One. 2017 Jan 18;12(1):e0168625.
Title:	The Role of Liquid Based Cytology and Ancillary Techniques in the Peritoneal Washing Analysis: Our Institutional Experience.
Author:	Rossi, Esther\|Bizzarro, Tommaso\|Martini, Maurizio\|Longatto-Filho, Adhemar\|Schmitt, Fernando\|Fagotti, Anna\|Scambia, Giovanni\|Zannoni, Gian Franco
PMID:	28099523

2934.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Jan 25;20(1):24-27.
Title:	[Improvement of prognostic and predictive network of colorectal cancer based upon the 8th edition of AJCC colorectal cancer staging system].
Author:	Yao, Hongwei\|Wu, Hongwei\|Liu, Yinhua
PMID:	28105615

2935.
Journal:	Int J Mol Sci. 2017 Jan 19;18(1). pii: ijms18010197.
Title:	Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.
Author:	Marmol, Ines\|Sanchez-de-Diego, Cristina\|Pradilla Dieste, Alberto\|Cerrada, Elena\|Rodriguez Yoldi, Maria Jesus
PMID:	28106826

2936.
Journal:	PLoS One. 2017 Jan 26;12(1):e0170775.
Title:	The Influence of BRAF and KRAS Mutation Status on the Association between Aspirin Use and Survival after Colon Cancer Diagnosis.
Author:	Frouws, Martine A\|Reimers, Marlies S\|Swets, Marloes\|Bastiaannet, Esther\|Prinse, Bianca\|van Eijk, Ronald\|Lemmens, Valery E P P\|van Herk-Sukel, Myrthe P P\|van Wezel, Tom\|Kuppen, Peter J K\|Morreau, Hans\|van de Velde, Cornelis J H\|Liefers, Gerrit-Jan
PMID:	28125730

2937.
Journal:	Mol Oncol. 2017 Feb;11(2):124-139.
Title:	Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.
Author:	Suzuki, Yuka\|Ng, Sarah Boonhsi\|Chua, Clarinda\|Leow, Wei Qiang\|Chng, Jermain\|Liu, Shi Yang\|Ramnarayanan, Kalpana\|Gan, Anna\|Ho, Dan Liang\|Ten, Rachel\|Su, Yan\|Lezhava, Alexandar\|Lai, Jiunn Herng\|Koh, Dennis\|Lim, Kiat Hon\|Tan, Patrick\|Rozen, Steven G\|Tan, Iai
PMID:	28145097

2938.
Journal:	Oncotarget. 2017 Mar 14;8(11):17810-17818.
Title:	EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics.
Author:	Yamamoto, Itaru\|Nosho, Katsuhiko\|Kanno, Shinichi\|Igarashi, Hisayoshi\|Kurihara, Hiroyoshi\|Ishigami, Keisuke\|Ishiguro, Kazuya\|Mitsuhashi, Kei\|Maruyama, Reo\|Koide, Hideyuki\|Okuda, Hiroyuki\|Hasegawa, Tadashi\|Sukawa, Yasutaka\|Okita, Kenji\|Takemasa, Ichiro\|Yama
PMID:	28147317

2939.
Journal:	Methods Mol Biol. 2017;1530:319-336.
Title:	Gene Silencing Using Multifunctionalized Gold Nanoparticles for Cancer Therapy.
Author:	Fernandes, Alexandra R\|Baptista, Pedro V
PMID:	28150211

2940.
Journal:	Br J Cancer. 2017 Feb 28;116(5):575-583.
Title:	A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor.
Author:	Bendell, Johanna C\|Javle, Milind\|Bekaii-Saab, Tanios S\|Finn, Richard S\|Wainberg, Zev A\|Laheru, Daniel A\|Weekes, Colin D\|Tan, Benjamin R\|Khan, Gazala N\|Zalupski, Mark M\|Infante, Jeffrey R\|Jones, Suzanne\|Papadopoulos, Kyriakos P\|Tolcher, Anthony W\|Chavira,
PMID:	28152546

2941.
Journal:	J Clin Pathol. 2017 Aug;70(8):702-711.
Title:	QMC-PCRx: a novel method for rapid mutation detection.
Author:	Ebili, Henry O\|Hassall, James\|Asiri, Abutaleb\|Ham-Karim, Hersh\|Fadhil, Wakkas\|Agboola, Ayodeji Johnson\|Ilyas, Mohammad
PMID:	28153952

2942.
Journal:	J Biol Chem. 2017 Mar 10;292(10):4164-4175.
Title:	USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer.
Author:	Fraile, Julia M\|Manchado, Eusebio\|Lujambio, Amaia\|Quesada, Victor\|Campos-Iglesias, Diana\|Webb, Thomas R\|Lowe, Scott W\|Lopez-Otin, Carlos\|Freije, Jose M P
PMID:	28154181

2943.
Journal:	Cancer Prev Res (Phila). 2017 Mar;10(3):208-218.
Title:	Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells.
Author:	Zumwalt, Timothy J\|Wodarz, Dominik\|Komarova, Natalia L\|Toden, Shusuke\|Turner, Jacob\|Cardenas, Jacob\|Burn, John\|Chan, Andrew T\|Boland, C Richard\|Goel, Ajay
PMID:	28154202

2944.
Journal:	Gastroenterol Res Pract. 2017;2017:8464905.
Title:	Chemotherapy Plus Cetuximab versus Chemotherapy Alone for Patients with KRAS Wild Type Unresectable Liver-Confined Metastases Colorectal Cancer: An Updated Meta-Analysis of RCTs.
Author:	Lv, W\|Zhang, G Q\|Jiao, A\|Zhao, B C\|Shi, Y\|Chen, B M\|Zhang, J L
PMID:	28167959

2945.
Journal:	Br J Cancer. 2017 Mar 14;116(6):802-810.
Title:	Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients.
Author:	Malapelle, Umberto\|Mayo de-Las-Casas, Clara\|Rocco, Danilo\|Garzon, Monica\|Pisapia, Pasquale\|Jordana-Ariza, Nuria\|Russo, Maria\|Sgariglia, Roberta\|De Luca, Caterina\|Pepe, Francesco\|Martinez-Bueno, Alejandro\|Morales-Espinosa, Daniela\|Gonzalez-Cao, Maria\|Karac
PMID:	28170370

2946.
Journal:	Mol Oncol. 2017 May;11(5):470-490.
Title:	Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Author:	Kalimutho, Murugan\|Bain, Amanda L\|Mukherjee, Bipasha\|Nag, Purba\|Nanayakkara, Devathri M\|Harten, Sarah K\|Harris, Janelle L\|Subramanian, Goutham N\|Sinha, Debottam\|Shirasawa, Senji\|Srihari, Sriganesh\|Burma, Sandeep\|Khanna, Kum Kum
PMID:	28173629

2947.
Journal:	Anticancer Res. 2017 Feb;37(2):651-657.
Title:	Comparative Study of Mutations in Single Nucleotide Polymorphism Loci of KRAS and BRAF Genes in Patients Who Underwent Screening Colonoscopy, With and Without Premalignant Intestinal Polyps.
Author:	Galanopoulos, Michail\|Papanikolaou, Ioannis S\|Zografos, Eleni\|Viazis, Nikos\|Papatheodoridis, George\|Karamanolis, Dimitrios\|Marinos, Evangelos\|Mantzaris, Gerassimos J\|Gazouli, Maria
PMID:	28179313

2948.
Journal:	Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title:	Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author:	Lee, Sung Hak\|Jung, Seung Hyun\|Kim, Tae-Min\|Rhee, Je-Keun\|Park, Hyeon-Chun\|Kim, Min Sung\|Kim, Sung Soo\|An, Chang Hyeok\|Lee, Sug Hyung\|Chung, Yeun-Jun
PMID:	28179590

2949.
Journal:	J Nutr Biochem. 2017 Apr;42:126-133.
Title:	Gene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial.
Author:	Nunez-Sanchez, Maria A\|Gonzalez-Sarrias, Antonio\|Garcia-Villalba, Rocio\|Monedero-Saiz, Tamara\|Garcia-Talavera, Noelia V\|Gomez-Sanchez, Maria B\|Sanchez-Alvarez, Carmen\|Garcia-Albert, Ana M\|Rodriguez-Gil, Francisco J\|Ruiz-Marin, Miguel\|Pastor-Quirante, Fran
PMID:	28183047

2950.
Journal:	Mol Cancer Res. 2017 Jun;15(6):708-713.
Title:	Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.
Author:	Ptashkin, Ryan N\|Pagan, Carlos\|Yaeger, Rona\|Middha, Sumit\|Shia, Jinru\|O'Rourke, Kevin P\|Berger, Michael F\|Wang, Lu\|Cimera, Robert\|Wang, Jiajing\|Klimstra, David S\|Saltz, Leonard\|Ladanyi, Marc\|Zehir, Ahmet\|Hechtman, Jaclyn F
PMID:	28184012

2951.
Journal:	Eur J Cardiothorac Surg. 2017 Feb 1;51(2):255-262.
Title:	Perioperative bevacizumab improves survival following lung metastasectomy for colorectal cancer in patients harbouring v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue exon 2 codon 12 mutationsdagger.
Author:	Renaud, Stephane\|Schaeffer, Mickael\|Falcoz, Pierre-Emmanuel\|Seitlinger, Joseph\|Romain, Benoit\|Voegeli, Anne-Claire\|Legrain, Michele\|Reeb, Jeremie\|Santelmo, Nicola\|Rohr, Serge\|Brigand, Cecile\|Olland, Anne\|Guenot, Dominique\|Massard, Gilbert
PMID:	28186237

2952.
Journal:	Hum Pathol. 2017 Jul;65:21-30.
Title:	KRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior.
Author:	Jang, Sejin\|Hong, Mineui\|Shin, Mi Kyung\|Kim, Byung Chun\|Shin, Hyung-Sik\|Yu, Eunsil\|Hong, Seung-Mo\|Kim, Jihun\|Chun, Sung-Min\|Kim, Tae-Im\|Choi, Kyung-Chan\|Ko, Young Woong\|Kim, Jeong Won
PMID:	28188750

2953.
Journal:	PLoS One. 2017 Feb 13;12(2):e0171435.
Title:	A novel RNA sequencing data analysis method for cell line authentication.
Author:	Fasterius, Erik\|Raso, Cinzia\|Kennedy, Susan\|Rauch, Nora\|Lundin, Par\|Kolch, Walter\|Uhlen, Mathias\|Al-Khalili Szigyarto, Cristina
PMID:	28192450

2954.
Journal:	BMC Cancer. 2017 Feb 16;17(1):139.
Title:	Clinical performance evaluation of a sensitive, rapid low-throughput test for KRAS mutation analysis using formalin-fixed, paraffin-embedded tissue samples.
Author:	Weyn, Christine\|Van Raemdonck, Sofie\|Dendooven, Robina\|Maes, Vincent\|Zwaenepoel, Karen\|Lambin, Suzan\|Pauwels, Patrick
PMID:	28201998

2955.
Journal:	Cancer Res. 2017 Apr 1;77(7):1763-1774.
Title:	Oncogenic Effects of High MAPK Activity in Colorectal Cancer Mark Progenitor Cells and Persist Irrespective of RAS Mutations.
Author:	Blaj, Cristina\|Schmidt, Eva Marina\|Lamprecht, Sebastian\|Hermeking, Heiko\|Jung, Andreas\|Kirchner, Thomas\|Horst, David
PMID:	28202525

2956.
Journal:	Br J Cancer. 2017 Mar 28;116(7):923-929.
Title:	Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer.
Author:	Jones, Robert P\|Sutton, Paul A\|Evans, Jonathan P\|Clifford, Rachel\|McAvoy, Andrew\|Lewis, James\|Rousseau, Abigail\|Mountford, Roger\|McWhirter, Derek\|Malik, Hassan Z
PMID:	28208157

2957.
Journal:	Exp Mol Pathol. 2017 Apr;102(2):255-261.
Title:	Detecting circulating tumor DNA in renal cancer: An open challenge.
Author:	Corro, Claudia\|Hejhal, Tomas\|Poyet, Cedric\|Sulser, Tullio\|Hermanns, Thomas\|Winder, Thomas\|Prager, Gerald\|Wild, Peter J\|Frew, Ian\|Moch, Holger\|Rechsteiner, Markus
PMID:	28214514

2958.
Journal:	Cell. 2017 Feb 23;168(5):817-829.e15.
Title:	KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer.
Author:	Burgess, Michael R\|Hwang, Eugene\|Mroue, Rana\|Bielski, Craig M\|Wandler, Anica M\|Huang, Benjamin J\|Firestone, Ari J\|Young, Amy\|Lacap, Jennifer A\|Crocker, Lisa\|Asthana, Saurabh\|Davis, Elizabeth M\|Xu, Jin\|Akagi, Keiko\|Le Beau, Michelle M\|Li, Qing\|Haley, Benja
PMID:	28215705

2959.
Journal:	Clin Colorectal Cancer. 2017 Sep;16(3):e153-e163.
Title:	Effect of KRAS and BRAF Mutations on Survival of Metastatic Colorectal Cancer After Liver Resection: A Systematic Review and Meta-Analysis.
Author:	Tosi, Federica\|Magni, Elena\|Amatu, Alessio\|Mauri, Gianluca\|Bencardino, Katia\|Truini, Mauro\|Veronese, Silvio\|De Carlis, Luciano\|Ferrari, Giovanni\|Nichelatti, Michele\|Sartore-Bianchi, Andrea\|Siena, Salvatore
PMID:	28216246

2960.
Journal:	Mol Carcinog. 2017 Jul;56(7):1743-1752.
Title:	Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.
Author:	Kai, Masahiro\|Yamamoto, Eiichiro\|Sato, Akiko\|Yamano, Hiro-O\|Niinuma, Takeshi\|Kitajima, Hiroshi\|Harada, Taku\|Aoki, Hironori\|Maruyama, Reo\|Toyota, Mutsumi\|Hatahira, Tomo\|Nakase, Hiroshi\|Sugai, Tamotsu\|Yamashita, Toshiharu\|Toyota, Minoru\|Suzuki, Hiromu
PMID:	28218473

2961.
Journal:	Genet Mol Res. 2017 Feb 16;16(1). pii: gmr-16-01-gmr.16019369.
Title:	Mutations in codons 12 and 13 of K-ras exon 2 in colorectal tumors of Saudi Arabian patients: frequency, clincopathological associations, and clinical outcomes.
Author:	Zekri, J\|Al-Shehri, A\|Mahrous, M\|Al-Rehaily, S\|Darwish, T\|Bassi, S\|El Taani, H\|Al Zahrani, A\|Elsamany, S\|Al-Maghrabi, J\|Sadiq, B B
PMID:	28218784

2962.
Journal:	J Pathol Transl Med. 2017 Mar;51(2):103-121.
Title:	Molecular Testing for Gastrointestinal Cancer.
Author:	Lee, Hye Seung\|Kim, Woo Ho\|Kwak, Yoonjin\|Koh, Jiwon\|Bae, Jeong Mo\|Kim, Kyoung-Mee\|Chang, Mee Soo\|Han, Hye Seung\|Kim, Joon Mee\|Kim, Hwal Woong\|Chang, Hee Kyung\|Choi, Young Hee\|Park, Ji Y\|Gu, Mi Jin\|Lhee, Min Jin\|Kim, Jung Yeon\|Kim, Hee Sung\|Cho, Mee-Yon
PMID:	28219002

2963.
Journal:	Tumour Biol. 2017 Feb;39(2):1010428317692265.
Title:	Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing-based cohort study.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Bp, Manasa\|Minhas, Sachin\|Shokeen, Yogender\|Aggarwal, Shyam
PMID:	28222664

2964.
Journal:	BMC Cancer. 2017 Feb 23;17(1):152.
Title:	Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report.
Author:	Tsujii, Yoshiki\|Hayashi, Yoshito\|Maekawa, Akira\|Fujinaga, Tetsuji\|Nagai, Kengo\|Yoshii, Shunsuke\|Sakatani, Akihiko\|Hiyama, Satoshi\|Shinzaki, Shinichiro\|Iijima, Hideki\|Takehara, Tetsuo
PMID:	28228152

2965.
Journal:	Case Rep Oncol Med. 2017;2017:6139634.
Title:	Clinical Application of Liquid Biopsy in Targeted Therapy of Metastatic Colorectal Cancer.
Author:	Trojan, Jorg\|Klein-Scory, Susanne\|Koch, Christine\|Schmiegel, Wolff\|Baraniskin, Alexander
PMID:	28232873

2966.
Journal:	Hum Pathol. 2017 Aug;66:1-9.
Title:	Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer.
Author:	Shimada, Yoshifumi\|Yagi, Ryoma\|Kameyama, Hitoshi\|Nagahashi, Masayuki\|Ichikawa, Hiroshi\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Mae\|Nakano, Masato\|Sato, Yo\|Matsuzawa, Takeaki\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|K
PMID:	28235632

2967.
Journal:	J Hematol Oncol. 2017 Feb 28;10(1):60.
Title:	Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Author:	Huang, Yan-Jiun\|Yang, Ching-Kuo\|Wei, Po-Li\|Huynh, Thanh-Tuan\|Whang-Peng, Jacqueline\|Meng, Tzu-Ching\|Hsiao, Michael\|Tzeng, Yew-Ming\|Wu, Alexander Th\|Yen, Yun
PMID:	28241877

2968.
Journal:	Mol Cancer Res. 2017 Jun;15(6):696-707.
Title:	CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.
Author:	Lal, Shruti\|Cheung, Edwin C\|Zarei, Mahsa\|Preet, Ranjan\|Chand, Saswati N\|Mambelli-Lisboa, Nicole C\|Romeo, Carmella\|Stout, Matthew C\|Londin, Eric\|Goetz, Austin\|Lowder, Cinthya Y\|Nevler, Avinoam\|Yeo, Charles J\|Campbell, Paul M\|Winter, Jordan M\|Dixon, Dan A\|B
PMID:	28242812

2969.
Journal:	Onco Targets Ther. 2017 Feb 16;10:945-953.
Title:	Effectiveness of circulating tumor DNA for detection of KRAS gene mutations in colorectal cancer patients: a meta-analysis.
Author:	Hao, Yi-Xin\|Fu, Qiang\|Guo, Yan-Yan\|Ye, Ming\|Zhao, Hui-Xia\|Wang, Qi\|Peng, Xiu-Mei\|Li, Qiu-Wen\|Wang, Ru-Liang\|Xiao, Wen-Hua
PMID:	28243130

2970.
Journal:	J Cancer. 2017 Jan 12;8(2):162-173.
Title:	Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform.
Author:	Peterfia, Balint\|Kalmar, Alexandra\|Patai, Arpad V\|Csabai, Istvan\|Bodor, Andras\|Micsik, Tamas\|Wichmann, Barnabas\|Egedi, Krisztina\|Hollosi, Peter\|Kovalszky, Ilona\|Tulassay, Zsolt\|Molnar, Bela
PMID:	28243320

2971.
Journal:	Oncologist. 2017 Mar;22(3):243-e23.
Title:	A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma.
Author:	Hecht, J Randolph\|Benson, Al B 3rd\|Vyushkov, Dmitry\|Yang, Yingsi\|Bendell, Johanna\|Verma, Udit
PMID:	28246207

2972.
Journal:	Gastroenterology. 2017 Jun;152(8):1944-1953.e1.
Title:	Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes.
Author:	Mehta, Raaj S\|Song, Mingyang\|Nishihara, Reiko\|Drew, David A\|Wu, Kana\|Qian, Zhi Rong\|Fung, Teresa T\|Hamada, Tsuyoshi\|Masugi, Yohei\|da Silva, Annacarolina\|Shi, Yan\|Li, Wanwan\|Gu, Mancang\|Willett, Walter C\|Fuchs, Charles S\|Giovannucci, Edward L\|Ogino, Shuji\|
PMID:	28249812

2973.
Journal:	BMC Cancer. 2017 Mar 4;17(1):170.
Title:	miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene.
Author:	Forzati, Floriana\|De Martino, Marco\|Esposito, Francesco\|Sepe, Romina\|Pellecchia, Simona\|Malapelle, Umberto\|Pellino, Gianluca\|Arra, Claudio\|Fusco, Alfredo
PMID:	28259135

2974.
Journal:	Onco Targets Ther. 2017 Feb 23;10:1143-1147.
Title:	Long-term survival after a favorable response to anti-EGFR antibody plus chemotherapy to treat bone marrow metastasis: a case report of KRAS-wildtype rectal cancer.
Author:	Nakamura, Sho\|Fukui, Tadahisa\|Suzuki, Shuhei\|Takeda, Hiroyuki\|Watanabe, Kaname\|Yoshioka, Takashi
PMID:	28260928

2975.
Journal:	Clin Case Rep. 2017 Feb 9;5(3):338-341.
Title:	A novel KRAS gene mutation report in sporadic colorectal cancer, from Northwest of Iran.
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Kermani, Iraj Asvadi\|Farassati, Faris\|Dastgiri, Saeed
PMID:	28265402

2976.
Journal:	PLoS One. 2017 Mar 7;12(3):e0173345.
Title:	Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer.
Author:	Mehrvarz Sarshekeh, Amir\|Advani, Shailesh\|Overman, Michael J\|Manyam, Ganiraju\|Kee, Bryan K\|Fogelman, David R\|Dasari, Arvind\|Raghav, Kanwal\|Vilar, Eduardo\|Manuel, Shanequa\|Shureiqi, Imad\|Wolff, Robert A\|Patel, Keyur P\|Luthra, Raja\|Shaw, Kenna\|Eng, Cathy\|Ma
PMID:	28267766

2977.
Journal:	Int J Cancer. 2017 Jun 15;140(12):2648-2656.
Title:	Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers.
Author:	Keum, NaNa\|Yuan, Chen\|Nishihara, Reiko\|Zoltick, Emilie\|Hamada, Tsuyoshi\|Martinez Fernandez, Alejandro\|Zhang, Xuehong\|Hanyuda, Akiko\|Liu, Li\|Kosumi, Keisuke\|Nowak, Jonathan A\|Jhun, Iny\|Soong, T Rinda\|Morikawa, Teppei\|Tabung, Fred K\|Qian, Zhi Rong\|Fuchs, Ch
PMID:	28268248

2978.
Journal:	J Natl Compr Canc Netw. 2017 Mar;15(3):370-398.
Title:	Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
Author:	Benson, Al B 3rd\|Venook, Alan P\|Cederquist, Lynette\|Chan, Emily\|Chen, Yi-Jen\|Cooper, Harry S\|Deming, Dustin\|Engstrom, Paul F\|Enzinger, Peter C\|Fichera, Alessandro\|Grem, Jean L\|Grothey, Axel\|Hochster, Howard S\|Hoffe, Sarah\|Hunt, Steven\|Kamel, Ahmed\|Kirilcu
PMID:	28275037

2979.
Journal:	Br J Cancer. 2017 Apr 11;116(8):1012-1020.
Title:	Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Kwak, Yoonjin\|Lee, Dae-Won\|Cha, Yongjun\|Wen, Xianyu\|Lee, Tae Hun\|Cho, Nam-Yun\|Jeong, Seung-Yong\|Park, Kyu Joo\|Han, Sae Won\|Lee, Hye Seung\|Kim, Tae-You\|Kang, Gyeong Hoon
PMID:	28278514

2980.
Journal:	Clin Cancer Res. 2017 Aug 1;23(15):4146-4154.
Title:	Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Parseghian, Christine M\|Parikh, Nila U\|Wu, Ji Yuan\|Jiang, Zhi-Qin\|Henderson, Laura\|Tian, Feng\|Pastor, Brice\|Ychou, Marc\|Raghav, Kanwal\|Dasari, Arvind\|Fogelman, David R\|Katsiampoura, Anastasia D\|Menter, David G\|Wolff, Robert A\|Eng, Cathy\|Overman, Michael J
PMID:	28280091

2981.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):1-11.
Title:	Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance).
Author:	Jansson-Knodell, Claire L\|Foster, Nathan R\|Sargent, Daniel J\|Limburg, Paul J\|Thibodeau, Stephen N\|Smyrk, Thomas C\|Sinicrope, Frank A\|Jahagirdar, Balkrishna\|Goldberg, Richard M\|Alberts, Steven R
PMID:	28280603

2982.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):55-63.
Title:	Clinical characteristics and treatment outcomes of patients with colorectal cancer who develop brain metastasis: a single institution experience.
Author:	Fountzilas, Christos\|Chang, Katherine\|Hernandez, Brian\|Michalek, Joel\|Crownover, Richard\|Floyd, John\|Mahalingam, Devalingam
PMID:	28280609

2983.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):109-126.
Title:	Differences in symptom occurrence, severity, and distress ratings between patients with gastrointestinal cancers who received chemotherapy alone or chemotherapy with targeted therapy.
Author:	Tantoy, Ilufredo Y\|Dhruva, Anand\|Cataldo, Janine\|Venook, Alan\|Cooper, Bruce A\|Paul, Steven M\|Levine, Jon D\|Conley, Yvette P\|Cartwright, Frances\|Lee, Kathryn\|Wright, Fay\|Miaskowski, Christine
PMID:	28280616

2984.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title:	Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author:	Borazanci, Erkut\|Millis, Sherri Z\|Kimbrough, Jeffery\|Doll, Nancy\|Von Hoff, Daniel\|Ramanathan, Ramesh K
PMID:	28280620

2985.
Journal:	J Gastrointest Oncol. 2017 Feb;8(1):199-212.
Title:	Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pie.
Author:	Loree, Jonathan M\|Kopetz, Scott\|Raghav, Kanwal P S
PMID:	28280626

2986.
Journal:	J Med Genet. 2017 Aug;54(8):567-571.
Title:	Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.
Author:	Madi, Ayman\|Fisher, David\|Maughan, Timothy S\|Colley, James P\|Meade, Angela M\|Tejpar, Sabine\|Van den Bosch, Ben\|Maynard, Julie\|Humphreys, Vikki\|Wasan, Harpreet\|Adams, Richard A\|Idziaszczyk, Shelley\|Harris, Rebecca\|Kaplan, Richard S\|Cheadle, Jeremy P
PMID:	28283541

2987.
Journal:	Genes Dev. 2017 Feb 15;31(4):370-382.
Title:	Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Author:	Boutin, Adam T\|Liao, Wen-Ting\|Wang, Melody\|Hwang, Soyoon Sarah\|Karpinets, Tatiana V\|Cheung, Hannah\|Chu, Gerald C\|Jiang, Shan\|Hu, Jian\|Chang, Kyle\|Vilar, Eduardo\|Song, Xingzhi\|Zhang, Jianhua\|Kopetz, Scott\|Futreal, Andrew\|Wang, Y Alan\|Kwong, Lawrence N\|DePi
PMID:	28289141

2988.
Journal:	J Clin Pathol. 2017 Jul;70(7):610-614.
Title:	Validating a fully automated real-time PCR-based system for use in the molecular diagnostic analysis of colorectal carcinoma: a comparison with NGS and IHC.
Author:	Colling, Richard\|Wang, Lai Mun\|Soilleux, Elizabeth
PMID:	28292978

2989.
Journal:	Cell Death Dis. 2017 Mar 16;8(3):e2669.
Title:	CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage.
Author:	Raats, Danielle A\|Frenkel, Nicola\|van Schelven, Susanne J\|Rinkes, Inne HMBorel\|Laoukili, Jamila\|Kranenburg, Onno
PMID:	28300842

2990.
Journal:	PLoS One. 2017 Mar 16;12(3):e0174151.
Title:	In vivo and ex vivo cetuximab sensitivity assay using three-dimensional primary culture system to stratify KRAS mutant colorectal cancer.
Author:	Tashiro, Takahiro\|Okuyama, Hiroaki\|Endo, Hiroko\|Kawada, Kenji\|Ashida, Yasuko\|Ohue, Masayuki\|Sakai, Yoshiharu\|Inoue, Masahiro
PMID:	28301591

2991.
Journal:	Anticancer Res. 2017 Mar;37(3):1105-1112.
Title:	Identification of Methylation Profiles of Cancer-related Genes in Circulating Tumor Cells Population.
Author:	Lyberopoulou, Anna\|Galanopoulos, Michail\|Aravantinos, Gerasimos\|Theodoropoulos, George E\|Marinos, Evangelos\|Efstathopoulos, Efstathios P\|Gazouli, Maria
PMID:	28314271

2992.
Journal:	Anticancer Res. 2017 Mar;37(3):1349-1357.
Title:	KRAS Mutant Status May Be Associated with Distant Recurrence in Early-stage Rectal Cancer.
Author:	Sideris, Michail\|Moorhead, Jane\|Diaz-Cano, Salvador\|Haji, Amyn\|Papagrigoriadis, Savvas
PMID:	28314302

2993.
Journal:	J Clin Pathol. 2017 Aug;70(8):720-723.
Title:	Intratumorous heterogeneity for RAS mutations in a treatment-naive colorectal tumour.
Author:	Lunke, Sebastian\|Lee, Belinda\|Kranz, Sevastjan\|Gibbs, Peter\|Waring, Paul\|Christie, Michael
PMID:	28314739

2994.
Journal:	Genes Dev. 2017 Feb 15;31(4):333-335.
Title:	No back seat for a progression event-K-RAS as a therapeutic target in CRC.
Author:	Poulin, Emily J\|Haigis, Kevin M
PMID:	28314765

2995.
Journal:	Mol Ther Nucleic Acids. 2017 Mar 17;6:140-149.
Title:	miR-134: A Human Cancer Suppressor?
Author:	Pan, Jing-Yu\|Zhang, Feng\|Sun, Cheng-Cao\|Li, Shu-Jun\|Li, Guang\|Gong, Feng-Yun\|Bo, Tao\|He, Jing\|Hua, Rui-Xi\|Hu, Wei-Dong\|Yuan, Zhan-Peng\|Wang, Xin\|He, Qi-Qiang\|Li, De-Jia
PMID:	28325280

2996.
Journal:	Cancer Prev Res (Phila). 2017 May;10(5):270-278.
Title:	Sessile Serrated Polyps and Colon Cancer Prevention.
Author:	Rashtak, Shahrooz\|Rego, Rafaela\|Sweetser, Seth R\|Sinicrope, Frank A
PMID:	28325827

2997.
Journal:	Ann Oncol. 2017 Jun 1;28(6):1359-1367.
Title:	Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance).
Author:	Fuchs, M A\|Yuan, C\|Sato, K\|Niedzwiecki, D\|Ye, X\|Saltz, L B\|Mayer, R J\|Mowat, R B\|Whittom, R\|Hantel, A\|Benson, A\|Atienza, D\|Messino, M\|Kindler, H\|Venook, A\|Innocenti, F\|Warren, R S\|Bertagnolli, M M\|Ogino, S\|Giovannucci, E L\|Horvath, E\|Meyerhardt, J A\|Ng, K
PMID:	28327908

2998.
Journal:	PLoS One. 2017 Mar 22;12(3):e0174140.
Title:	KRAS and VEGF gene 3'-UTR single nucleotide polymorphisms predicted susceptibility in colorectal cancer.
Author:	Yang, Minnan\|Xiao, Xiuli\|Xing, Xiaorui\|Li, Xin\|Xia, Tian\|Long, Hanan
PMID:	28328959

2999.
Journal:	Oncol Rep. 2017 May;37(5):3128-3136.
Title:	Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor.
Author:	Kawasaki, Hideyoshi\|Saotome, Takuya\|Usui, Tatsuya\|Ohama, Takashi\|Sato, Koichi
PMID:	28339087

3000.
Journal:	Tumour Biol. 2017 Mar;39(3):1010428317692246.
Title:	Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers.
Author:	Kleist, Britta\|Meurer, Thuja\|Poetsch, Micaela
PMID:	28345467

3001.
Journal:	Invest New Drugs. 2017 Aug;35(4):491-498.
Title:	Phase II study of the Multikinase inhibitor of angiogenesis, Linifanib, in patients with metastatic and refractory colorectal cancer expressing mutated KRAS.
Author:	Chan, Emily\|Goff, Laura W\|Cardin, Dana B\|Ancell, Kristin\|Smith, Stephen James\|Whisenant, Jennifer G\|Ye, Fei\|Berlin, Jordan D
PMID:	28353122

3002.
Journal:	Arch Pathol Lab Med. 2017 Apr;141(4):564-568.
Title:	SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma.
Author:	Lasota, Jerzy\|Kowalik, Artur\|Felisiak-Golabek, Anna\|Inaguma, Shingo\|Wang, Zeng-Feng\|Pieciak, Liliana\|Zieba, Sebastian\|Peksa, Rafal\|Kopczynski, Janusz\|Okon, Krzysztof\|Waloszczyk, Piotr\|Gozdz, Stanislaw\|Biernat, Wojciech\|Miettinen, Markku
PMID:	28353383

3003.
Journal:	Cell Mol Biol (Noisy-le-grand). 2017 Feb 28;63(2):79-87.
Title:	The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer.
Author:	Tokarz, P\|Pawlowska, E\|Bialkowska-Warzecha, J\|Blasiak, J
PMID:	28364795

3004.
Journal:	J BUON. 2017 Jan-Feb;22(1):178-183.
Title:	Cell-free DNA as biomarker and source for mutation detection in primary colorectal cancer.
Author:	Nikolic, Aleksandra\|Vlajnic, Marina\|Ristanovic, Momcilo\|Petrovic, Jelena\|Dimitrijevic, Ivan\|Krivokapic, Zoran\|Radojkovic, Dragica
PMID:	28365952

3005.
Journal:	Expert Opin Ther Pat. 2017 May;27(5):527-538.
Title:	Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1.
Author:	Plano, Daniel\|Alcolea, Veronica\|Sanmartin, Carmen\|Sharma, Arun K
PMID:	28366103

3006.
Journal:	Oncogene. 2017 Jul 27;36(30):4336-4348.
Title:	TGFbeta engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.
Author:	Principe, D R\|Diaz, A M\|Torres, C\|Mangan, R J\|DeCant, B\|McKinney, R\|Tsao, M-S\|Lowy, A\|Munshi, H G\|Jung, B\|Grippo, P J
PMID:	28368414

3007.
Journal:	Cancer Med. 2017 May;6(5):1023-1035.
Title:	DNA methylation epigenotype and clinical features of NRAS-mutation(+) colorectal cancer.
Author:	Takane, Kiyoko\|Akagi, Kiwamu\|Fukuyo, Masaki\|Yagi, Koichi\|Takayama, Tadatoshi\|Kaneda, Atsushi
PMID:	28378457

3008.
Journal:	J Pathol Inform. 2017 Mar 10;8:13.
Title:	Performance of a Web-based Method for Generating Synoptic Reports.
Author:	Renshaw, Megan A\|Renshaw, Scott A\|Mena-Allauca, Mercy\|Carrion, Patricia P\|Mei, Xiaorong\|Narciandi, Arniris\|Gould, Edwin W\|Renshaw, Andrew A
PMID:	28382227

3009.
Journal:	Sensors (Basel). 2017 Apr 11;17(4). pii: s17040831.
Title:	Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping.
Author:	Guarnaccia, Maria\|Iemmolo, Rosario\|Petralia, Salvatore\|Conoci, Sabrina\|Cavallaro, Sebastiano
PMID:	28398227

3010.
Journal:	Acta Cir Bras. 2017 Mar;32(3):243-250.
Title:	Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors.
Author:	Carvalho, Thais Inacio de\|Novais, Paulo Cezar\|Lizarte, Fermino Sanches Neto\|Sicchieri, Renata Danielle\|Rosa, Marcella Suelma Torrecillas\|Carvalho, Camila Albuquerque Mello de\|Tirapelli, Daniela Pretti da Cunha\|Peria, Fernanda Maris\|Rocha, Jose Joaquim Rib
PMID:	28403349

3011.
Journal:	Oncoimmunology. 2017 Jan 31;6(3):e1284720.
Title:	Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
Author:	Kosumi, Keisuke\|Masugi, Yohei\|Yang, Juhong\|Qian, Zhi Rong\|Kim, Sun A\|Li, Wanwan\|Shi, Yan\|da Silva, Annacarolina\|Hamada, Tsuyoshi\|Liu, Li\|Gu, Mancang\|Twombly, Tyler S\|Cao, Yin\|Barbie, David A\|Nosho, Katsuhiko\|Baba, Hideo\|Garrett, Wendy S\|Meyerhardt, Jeffer
PMID:	28405513

3012.
Journal:	J Clin Oncol. 2017 Jun 1;35(16):1836-1844.
Title:	Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.
Author:	Hamada, Tsuyoshi\|Cao, Yin\|Qian, Zhi Rong\|Masugi, Yohei\|Nowak, Jonathan A\|Yang, Juhong\|Song, Mingyang\|Mima, Kosuke\|Kosumi, Keisuke\|Liu, Li\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Keum, NaNa\|Zhang, Xuehong\|Wu, Kana\|Meyerhardt, Jeffrey A\|Giova
PMID:	28406723

3013.
Journal:	Biomed J. 2017 Feb;40(1):39-48.
Title:	Overexpression of MutL homolog 1 and MutS homolog 2 proteins have reversed prognostic implications for stage I-II colon cancer patients.
Author:	Huang, Shih-Chiang\|Huang, Shiu-Feng\|Chen, Ya-Ting\|Chang, Yu\|Chiu, Yu-Ting\|Chang, Il-Chi\|Wu, Hong-Dar Isaac\|Chen, Jinn-Shiun
PMID:	28411881

3014.
Journal:	Oncotarget. 2017 May 23;8(21):34283-34297.
Title:	Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens.
Author:	Christodoulou, Eleni G\|Yang, Hai\|Lademann, Franziska\|Pilarsky, Christian\|Beyer, Andreas\|Schroeder, Michael
PMID:	28415695

3015.
Journal:	Oncotarget. 2017 Jul 25;8(30):49076-49083.
Title:	The molecular heterogeneity of sporadic colorectal cancer with different tumor sites in Chinese patients.
Author:	Peng, Junjie\|Huang, Dan\|Poston, Graeme\|Ma, Xiaoji\|Wang, Renjie\|Sheng, Weiqi\|Zhou, Xiaoyan\|Zhu, Xiaoli\|Cai, Sanjun
PMID:	28416767

3016.
Journal:	Adv Healthc Mater. 2017 Jul;6(13).
Title:	Panitumumab-Conjugated Pt-Drug Nanomedicine for Enhanced Efficacy of Combination Targeted Chemotherapy against Colorectal Cancer.
Author:	Tsai, Ming-Hsien\|Pan, Chao-Hsuan\|Peng, Cheng-Liang\|Shieh, Ming-Jium
PMID:	28418176

3017.
Journal:	Oncotarget. 2017 May 23;8(21):35138-35153.
Title:	Toll like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer.
Author:	Maitra, Radhashree\|Augustine, Titto\|Dayan, Yitzchak\|Chandy, Carol\|Coffey, Matthew\|Goel, Sanjay
PMID:	28422714

3018.
Journal:	Int J Colorectal Dis. 2017 Aug;32(8):1179-1190.
Title:	Final analysis of the randomised PEAK trial: overall survival and tumour responses during first-line treatment with mFOLFOX6 plus either panitumumab or bevacizumab in patients with metastatic colorectal carcinoma.
Author:	Rivera, Fernando\|Karthaus, Meinolf\|Hecht, J Randolph\|Sevilla, Isabel\|Forget, Frederic\|Fasola, Gianpiero\|Canon, Jean-Luc\|Guan, Xuesong\|Demonty, Gaston\|Schwartzberg, Lee S
PMID:	28424871

3019.
Journal:	Mod Pathol. 2017 Aug;30(8):1177-1189.
Title:	Mapping clinicopathological entities within colorectal mucinous adenocarcinomas: a hierarchical clustering approach.
Author:	Liddell, Charly\|Droy-Dupre, Laure\|Metairie, Sylvie\|Airaud, Fabrice\|Volteau, Christelle\|Bezieau, Stephane\|Laboisse, Christian L\|Mosnier, Jean-Francois
PMID:	28429715

3020.
Journal:	Pathology. 2017 Jun;49(4):387-390.
Title:	NRASQ61R immunohistochemistry detects both NRASQ61R and KRASQ61R mutations in colorectal cancer.
Author:	Jhuang, Jie-Yang\|Yuan, Chang-Tsu\|Lin, Yu-Lin\|Cheng, Mei-Ling\|Liau, Jau-Yu\|Tsai, Jia-Huei
PMID:	28433252

3021.
Journal:	Theranostics. 2017 Feb 27;7(5):1114-1132.
Title:	The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer.
Author:	Wu, De-Wei\|Lin, Po-Lin\|Wang, Lee\|Huang, Chi-Chou\|Lee, Huei
PMID:	28435452

3022.
Journal:	Hum Pathol. 2017 Jun;64:179-185.
Title:	Clinicopathological, immunohistochemical, and mutational analyses of pulmonary enteric adenocarcinoma: usefulness of SATB2 and beta-catenin immunostaining for differentiation from metastatic colorectal carcinoma.
Author:	Matsushima, Jun\|Yazawa, Takuya\|Suzuki, Masaki\|Takahashi, Yoko\|Ota, Satoshi\|Nakajima, Takahiro\|Yoshino, Ichiro\|Yokose, Tomoyuki\|Inoue, Toru\|Kawahara, Kunimitsu\|Nakatani, Yukio
PMID:	28438615

3023.
Journal:	Oncotarget. 2017 Jun 13;8(24):38581-38591.
Title:	Selective eradication of cancer cells by delivery of adenovirus-based toxins.
Author:	Shapira, Shiran\|Shapira, Assaf\|Kazanov, Diana\|Hevroni, Gil\|Kraus, Sarah\|Arber, Nadir
PMID:	28445136

3024.
Journal:	Clin Cancer Res. 2017 Aug 15;23(16):4753-4760.
Title:	Clinical Features and Outcomes of Patients with Colorectal Cancers Harboring NRAS Mutations.
Author:	Cercek, Andrea\|Braghiroli, Maria Ignez\|Chou, Joanne F\|Hechtman, Jaclyn F\|Kemeny, Nancy\|Saltz, Leonard\|Capanu, Marinela\|Yaeger, Rona
PMID:	28446505

3025.
Journal:	Acta Oncol. 2017 May;56(5):639-645.
Title:	Risk factors for brain metastases in patients with metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Hogdall, Estrid\|Poulsen, Tim Svenstrup\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Christensen, Ib Jarle\|Nielsen, Dorte
PMID:	28447565

3026.
Journal:	Mol Clin Oncol. 2017 Mar;6(3):403-408.
Title:	Role of RAS mutation status as a prognostic factor for patients with advanced colorectal cancer treated with first-line chemotherapy based on fluoropyrimidines and oxaliplatin, with or without bevavizumab: A retrospective analysis.
Author:	Garde Noguera, Javier\|Jantus-Lewintre, Eloisa\|Gil-Raga, Mireia\|Evgenyeva, Elena\|Macia Escalante, Sonia\|Llombart-Cussac, Antonio\|Camps Herrero, Carlos
PMID:	28451421

3027.
Journal:	Ann Oncol. 2017 May 1;28(5):958-968.
Title:	Subgroups and prognostication in stage III colon cancer: future perspectives for adjuvant therapy.
Author:	Auclin, E\|Zaanan, A\|Vernerey, D\|Douard, R\|Gallois, C\|Laurent-Puig, P\|Bonnetain, F\|Taieb, J
PMID:	28453690

3028.
Journal:	Ann Oncol. 2017 May 1;28(5):1023-1031.
Title:	Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.
Author:	Dienstmann, R\|Mason, M J\|Sinicrope, F A\|Phipps, A I\|Tejpar, S\|Nesbakken, A\|Danielsen, S A\|Sveen, A\|Buchanan, D D\|Clendenning, M\|Rosty, C\|Bot, B\|Alberts, S R\|Milburn Jessup, J\|Lothe, R A\|Delorenzi, M\|Newcomb, P A\|Sargent, D\|Guinney, J
PMID:	28453697

3029.
Journal:	Nat Biotechnol. 2017 Jun;35(6):569-576.
Title:	In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Author:	Roper, Jatin\|Tammela, Tuomas\|Cetinbas, Naniye Malli\|Akkad, Adam\|Roghanian, Ali\|Rickelt, Steffen\|Almeqdadi, Mohammad\|Wu, Katherine\|Oberli, Matthias A\|Sanchez-Rivera, Francisco J\|Park, Yoona K\|Liang, Xu\|Eng, George\|Taylor, Martin S\|Azimi, Roxana\|Kedrin, Dmi
PMID:	28459449

3030.
Journal:	Oncogene. 2017 Aug 31;36(35):5035-5044.
Title:	Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia.
Author:	Hanley, M P\|Hahn, M A\|Li, A X\|Wu, X\|Lin, J\|Wang, J\|Choi, A H\|Ouyang, Z\|Fong, Y\|Pfeifer, G P\|Devers, T J\|Rosenberg, D W
PMID:	28459462

3031.
Journal:	Oncogene. 2017 Aug 31;36(35):4975-4986.
Title:	Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer.
Author:	Pek, M\|Yatim, S M J M\|Chen, Y\|Li, J\|Gong, M\|Jiang, X\|Zhang, F\|Zheng, J\|Wu, X\|Yu, Q
PMID:	28459468

3032.
Journal:	PLoS One. 2017 May 1;12(5):e0176340.
Title:	Feasibility of multiplexed gene mutation detection in plasma samples of colorectal cancer patients by mass spectrometric genotyping.
Author:	Shin, Su-Jin\|Chun, Sung-Min\|Kim, Tae-Im\|Kim, Yu Jin\|Choi, Hyun-Jeung\|Jang, Se Jin\|Kim, Jihun
PMID:	28459822

3033.
Journal:	J Biol Chem. 2017 Jun 16;292(24):10142-10152.
Title:	HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers.
Author:	Zhao, Liang\|Fan, Jun\|Xia, Siyuan\|Pan, Yaozhu\|Liu, Shuangping\|Qian, Guoqing\|Qian, Zhiyu\|Kang, Hee-Bum\|Arbiser, Jack L\|Pollack, Brian P\|Kudchadkar, Ragini R\|Lawson, David H\|Rossi, Michael\|Abdel-Wahab, Omar\|Merghoub, Taha\|Khoury, Hanna J\|Khuri, Fadlo R\|Boise
PMID:	28468827

3034.
Journal:	Sci Rep. 2017 May 4;7(1):1502.
Title:	Rationally co-targeting divergent pathways in KRAS wild-type colorectal cancers by CANscript technology reveals tumor dependence on Notch and Erbb2.
Author:	Brijwani, Nilesh\|Jain, Misti\|Dhandapani, Muthu\|Zahed, Farrah\|Mukhopadhyay, Pragnashree\|Biswas, Manjusha\|Khatri, Deepak\|Radhakrishna, Vinod D\|Majumder, Biswanath\|Radhakrishnan, Padhma\|Thiyagarajan, Saravanan
PMID:	28473715

3035.
Journal:	Cell Death Differ. 2017 Jul;24(7):1253-1262.
Title:	MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1.
Author:	Shen, Hongxing\|Xing, Chuan\|Cui, Kaisa\|Li, Yunxiao\|Zhang, Jinxiang\|Du, Runlei\|Zhang, Xiaodong\|Li, Youjun
PMID:	28475173

3036.
Journal:	Oncotarget. 2017 Jun 27;8(26):42487-42494.
Title:	Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma.
Author:	Vakiani, Efsevia\|Shah, Ronak H\|Berger, Michael F\|Makohon-Moore, Alvin P\|Reiter, Johannes G\|Ostrovnaya, Irina\|Attiyeh, Marc A\|Cercek, Andrea\|Shia, Jinru\|Iacobuzio-Donahue, Christine A\|Solit, David B\|Weiser, Martin R
PMID:	28476018

3037.
Journal:	BMC Genomics. 2017 May 9;18(1):361.
Title:	Associating transcriptional modules with colon cancer survival through weighted gene co-expression network analysis.
Author:	Liu, Rong\|Zhang, Wei\|Liu, Zhao-Qian\|Zhou, Hong-Hao
PMID:	28486948

3038.
Journal:	Tumour Biol. 2017 May;39(5):1010428317705749.
Title:	Future perspectives of circulating tumor DNA in colorectal cancer.
Author:	Nadal, C\|Winder, T\|Gerger, A\|Tougeron, David
PMID:	28488528

3039.
Journal:	Gastrointest Endosc. 2017 Dec;86(6):1131-1138.e4.
Title:	Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.
Author:	Tanaka, Yoshihito\|Yamano, Hiro-O\|Yamamoto, Eiichiro\|Matushita, Hiro-O\|Aoki, Hironori\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Harada, Eiji\|Nakaoka, Michiko\|Yoshida, Yuko\|Eizuka, Makoto\|Sugai, Tamotsu\|Suzuki, Hiromu\|Nakase, Hiroshi
PMID:	28501592

3040.
Journal:	Target Oncol. 2017 Jun;12(3):265-275.
Title:	What We Know About Stage II and III Colon Cancer: It's Still Not Enough.
Author:	Puccini, Alberto\|Berger, Martin D\|Zhang, Wu\|Lenz, Heinz-Josef
PMID:	28504299

3041.
Journal:	Oncologist. 2017 Jul;22(7):774-779.
Title:	Detection of an ALK Fusion in Colorectal Carcinoma by Hybrid Capture-Based Assay of Circulating Tumor DNA.
Author:	Lai, Andrea Z\|Schrock, Alexa B\|Erlich, Rachel L\|Ross, Jeffrey S\|Miller, Vincent A\|Yakirevich, Evgeny\|Ali, Siraj M\|Braiteh, Fadi
PMID:	28507204

3042.
Journal:	J Cancer Res Ther. 2017 Jan-Mar;13(1):156.
Title:	Retraction: Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta analysis.
Author:
PMID:	28508855

3043.
Journal:	Gastroenterology. 2017 Aug;153(2):470-479.e4.
Title:	Statin Use After Diagnosis of Colon Cancer and Patient Survival.
Author:	Voorneveld, Philip W\|Reimers, Marlies S\|Bastiaannet, Esther\|Jacobs, Rutger J\|van Eijk, Ronald\|Zanders, Marjolein M J\|Herings, Ron M C\|van Herk-Sukel, Myrthe P P\|Kodach, Liudmila L\|van Wezel, Tom\|Kuppen, Peter J K\|Morreau, Hans\|van de Velde, Cornelis J H\|H
PMID:	28512021

3044.
Journal:	Cancer Res. 2017 Jul 15;77(14):3814-3822.
Title:	A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer.
Author:	Kloosterman, Wigard P\|Coebergh van den Braak, Robert R J\|Pieterse, Mark\|van Roosmalen, Markus J\|Sieuwerts, Anieta M\|Stangl, Christina\|Brunekreef, Ronne\|Lalmahomed, Zarina S\|Ooft, Salo\|van Galen, Anne\|Smid, Marcel\|Lefebvre, Armel\|Zwartkruis, Fried\|Martens,
PMID:	28512242

3045.
Journal:	Cancer. 2017 Sep 15;123(18):3513-3523.
Title:	Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer.
Author:	Lee, Dae-Won\|Han, Sae-Won\|Cha, Yongjun\|Bae, Jeong Mo\|Kim, Hwang-Phill\|Lyu, Jaemyun\|Han, Hyojun\|Kim, Hyoki\|Jang, Hoon\|Bang, Duhee\|Huh, Iksoo\|Park, Taesung\|Won, Jae-Kyung\|Jeong, Seung-Yong\|Park, Kyu Joo\|Kang, Gyeong Hoon\|Kim, Tae-You
PMID:	28513830

3046.
Journal:	Oncol Lett. 2017 May;13(5):3608-3616.
Title:	KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population.
Author:	Hao, Yi-Xin\|Li, Yong-Mei\|Ye, Ming\|Guo, Yan-Yan\|Li, Qiu-Wen\|Peng, Xiu-Mei\|Wang, Qi\|Zhang, Shu-Fang\|Zhao, Hui-Xia\|Zhang, He\|Li, Guang-Hui\|Zhu, Jian-Hua\|Xiao, Wen-Hua
PMID:	28521461

3047.
Journal:	Br J Cancer. 2017 Jun 6;116(12):1652-1659.
Title:	Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.
Author:	Gray, Ronan T\|Loughrey, Maurice B\|Bankhead, Peter\|Cardwell, Chris R\|McQuaid, Stephen\|O'Neill, Roisin F\|Arthur, Kenneth\|Bingham, Victoria\|McGready, Claire\|Gavin, Anna T\|James, Jacqueline A\|Hamilton, Peter W\|Salto-Tellez, Manuel\|Murray, Liam J\|Coleman, Hele
PMID:	28524155

3048.
Journal:	Br J Cancer. 2017 Jun 27;117(1):136-143.
Title:	Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.
Author:	Chakrabarty, Sanjiban\|Varghese, Vinay Koshy\|Sahu, Pranoy\|Jayaram, Pradyumna\|Shivakumar, Bhadravathi M\|Pai, Cannanore Ganesh\|Satyamoorthy, Kapaettu
PMID:	28524162

3049.
Journal:	Biochem Biophys Res Commun. 2017 Jul 8;488(4):578-583.
Title:	Phospholipase C delta1 negatively regulates autophagy in colorectal cancer cells.
Author:	Shimozawa, Makoto\|Anzai, Sakiho\|Satow, Reiko\|Fukami, Kiyoko
PMID:	28528980

3050.
Journal:	Carcinogenesis. 2017 Aug 1;38(8):837-846.
Title:	Gender-related prognostic value and genomic pattern of intra-tumor heterogeneity in colorectal cancer.
Author:	Zhang, Jieyun\|Yan, Shican\|Liu, Xiyu\|Gan, Lu\|Wu, Zhenhua\|Gong, Yiwei\|Huang, Mingzhu\|Zhang, Xiaowei\|Guo, Weijian
PMID:	28531253

3051.
Journal:	Gan To Kagaku Ryoho. 2017 May;44(5):417-420.
Title:	[A Case Report on a Successful Resection after FOLFIRI plus Cetuximab Therapy for Unresectable Colorectal Cancer with Multiple Liver Metastases].
Author:	Kanamori, Min\|Kurumiya, Yasuhiro\|Mizuno, Keisuke\|Sekoguchi, Ei\|Kobayashi, Satoshi\|Fukami, Yasuyuki\|Kiriyama, Muneyasu\|Aoyama, Hiroki\|Oiwa, Takashi\|Miyamura, Kei\|Jinno, Takanori\|Nakashima, Yu\|Mori, Makiko
PMID:	28536339

3052.
Journal:	Yonsei Med J. 2017 Jul;58(4):749-755.
Title:	Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer.
Author:	Sambuudash, Otgontuya\|Kim, Hyun Soo\|Cho, Mee Yon
PMID:	28540987

3053.
Journal:	Mod Pathol. 2017 Aug;30(8):1152-1169.
Title:	Infrequently expressed miRNAs in colorectal cancer tissue and tumor molecular phenotype.
Author:	Slattery, Martha L\|Lee, Frances Y\|Pellatt, Andrew J\|Mullany, Lila E\|Stevens, John R\|Samowitz, Wade S\|Wolff, Roger K\|Herrick, Jennifer S
PMID:	28548123

3054.
Journal:	EBioMedicine. 2017 Jun;20:39-49.
Title:	A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.
Author:	Viel, Alessandra\|Bruselles, Alessandro\|Meccia, Ettore\|Fornasarig, Mara\|Quaia, Michele\|Canzonieri, Vincenzo\|Policicchio, Eleonora\|Urso, Emanuele Damiano\|Agostini, Marco\|Genuardi, Maurizio\|Lucci-Cordisco, Emanuela\|Venesio, Tiziana\|Martayan, Aline\|Diodoro, M
PMID:	28551381

3055.
Journal:	Pathol Res Pract. 2017 Jun;213(6):606-611.
Title:	Influence of mucinous and necrotic tissue in colorectal cancer samples on KRAS mutation analysis.
Author:	Buttner, Juliane\|Lehmann, Annika\|Klauschen, Frederick\|Hummel, Michael\|Lenze, Dido\|Dietel, Manfred\|Johrens, Korinna
PMID:	28551386

3056.
Journal:	Anticancer Res. 2017 Jun;37(6):2831-2838.
Title:	MEK162 Enhances Antitumor Activity of 5-Fluorouracil and Trifluridine in KRAS-mutated Human Colorectal Cancer Cell Lines.
Author:	Gong, Jun\|Chen, Yuan\|Yang, Lixin\|Pillai, Raju\|Shirasawa, Senji\|Fakih, Marwan
PMID:	28551618

3057.
Journal:	Am J Cancer Res. 2017 May 1;7(5):1227-1237. eCollection 2017.
Title:	The identification and validation of Trichosstatin A as a potential inhibitor of colon tumorigenesis and colon cancer stem-like cells.
Author:	Huang, Tse-Hung\|Wu, Szu-Yuan\|Huang, Yan-Jiun\|Wei, Po-Li\|Wu, Alexander Th\|Chao, Tsu-Yi
PMID:	28560069

3058.
Journal:	Oncol Rep. 2017 Jul;38(1):263-270.
Title:	EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells.
Author:	Cuyas, Elisabet\|Queralt, Bernardo\|Martin-Castillo, Begona\|Bosch-Barrera, Joaquim\|Menendez, Javier A
PMID:	28560458

3059.
Journal:	Nat Commun. 2017 May 31;8:15107.
Title:	Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
Author:	Isella, Claudio\|Brundu, Francesco\|Bellomo, Sara E\|Galimi, Francesco\|Zanella, Eugenia\|Porporato, Roberta\|Petti, Consalvo\|Fiori, Alessandro\|Orzan, Francesca\|Senetta, Rebecca\|Boccaccio, Carla\|Ficarra, Elisa\|Marchionni, Luigi\|Trusolino, Livio\|Medico, Enzo\|Ber
PMID:	28561063

3060.
Journal:	World J Gastrointest Oncol. 2017 May 15;9(5):209-217.
Title:	Extramural vascular invasion and response to neoadjuvant chemoradiotherapy in rectal cancer: Influence of the CpG island methylator phenotype.
Author:	Williamson, Jeremy Stuart\|Jones, Huw Geraint\|Williams, Namor\|Griffiths, Anthony Paul\|Jenkins, Gareth\|Beynon, John\|Harris, Dean Anthony
PMID:	28567185

3061.
Journal:	Cell Death Dis. 2017 Jun 1;8(6):e2843.
Title:	The novel hypoxia-inducible factor-1alpha inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
Author:	Ban, Hyun Seung\|Kim, Bo-Kyung\|Lee, Hongsub\|Kim, Hwan Mook\|Harmalkar, Dipesh\|Nam, Miso\|Park, Song-Kyu\|Lee, Kiho\|Park, Joon-Tae\|Kim, Inhyub\|Lee, Kyeong\|Hwang, Geum-Sook\|Won, Misun
PMID:	28569777

3062.
Journal:	Onco Targets Ther. 2017 May 19;10:2645-2654.
Title:	Association between clinicopathological features and survival in patients with primary and paired metastatic colorectal cancer and KRAS mutation.
Author:	Pang, Xue-Lian\|Li, Qiao-Xin\|Ma, Zhi-Ping\|Shi, Yi\|Ma, Yu-Qing\|Li, Xin-Xia\|Cui, Wen-Li\|Zhang, Wei
PMID:	28579802

3063.
Journal:	Front Pharmacol. 2017 May 19;8:267.
Title:	The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer.
Author:	Balch, Curt\|Ramapuram, Jayaram B\|Tiwari, Amit K
PMID:	28579957

3064.
Journal:	Cell J. 2017 Spring;19(Suppl 1):113-117.
Title:	Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity.
Author:	Larki, Pegah\|Gharib, Ehsan\|Yaghoob Taleghani, Mohammad\|Khorshidi, Fatemeh\|Nazemalhosseini-Mojarad, Ehsan\|Asadzadeh Aghdaei, Hamid
PMID:	28580315

3065.
Journal:	BMC Cancer. 2017 Jun 5;17(1):403.
Title:	The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.
Author:	Won, Daeyoun David\|Lee, Jae Im\|Lee, In Kyu\|Oh, Seong-Taek\|Jung, Eun Sun\|Lee, Sung Hak
PMID:	28583095

3066.
Journal:	Nat Commun. 2017 Jun 8;8:15617.
Title:	Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance.
Author:	Ali, Moiez\|Kaltenbrun, Erin\|Anderson, Grace R\|Stephens, Sarah Jo\|Arena, Sabrina\|Bardelli, Alberto\|Counter, Christopher M\|Wood, Kris C
PMID:	28593995

3067.
Journal:	Oncol Lett. 2017 Jun;13(6):4720-4726.
Title:	Colorectal cancer in cases of multiple primary cancers: Clinical features of 59 cases and point mutation analyses.
Author:	Wu, Anshan\|He, Siqi\|Li, Jingjing\|Liu, Ling\|Liu, Chunlan\|Wang, Qi\|Peng, Xiaowei\|Zhou, Jianda\|Cao, Pei-Guo\|Cao, Ke
PMID:	28599473

3068.
Journal:	Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2073-2083.
Title:	Mucosa-associated microbiota signature in colorectal cancer.
Author:	Gao, R\|Kong, C\|Huang, L\|Li, H\|Qu, X\|Liu, Z\|Lan, P\|Wang, J\|Qin, H
PMID:	28600626

3069.
Journal:	Mol Cancer Ther. 2017 Oct;16(10):2178-2190.
Title:	A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers.
Author:	Cho, Sung-Yup\|Han, Jee Yun\|Na, Deukchae\|Kang, Wonyoung\|Lee, Ahra\|Kim, Jooyoung\|Lee, Jieun\|Min, Seoyeon\|Kang, Jinjoo\|Chae, Jeesoo\|Kim, Jong-Il\|Park, Hansoo\|Lee, Won-Suk\|Lee, Charles
PMID:	28611106

3070.
Journal:	Clin Cancer Res. 2017 Sep 15;23(18):5547-5560.
Title:	Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with BRAF or KRAS Mutations.
Author:	Yao, Yung-Mae M\|Donoho, Gregory P\|Iversen, Philip W\|Zhang, Youyan\|Van Horn, Robert D\|Forest, Amelie\|Novosiadly, Ruslan D\|Webster, Yue Wang\|Ebert, Philip\|Bray, Steven\|Ting, Jason C\|Aggarwal, Amit\|Henry, James R\|Tiu, Ramon V\|Plowman, Gregory D\|Peng, Sheng-B
PMID:	28611205

3071.
Journal:	Visc Med. 2017 Mar;33(1):47-53.
Title:	Treatment Options in Colorectal Liver Metastases: Hepatic Arterial Infusion.
Author:	Zervoudakis, Alice\|Boucher, Taryn\|Kemeny, Nancy E
PMID:	28612017

3072.
Journal:	Gut Pathog. 2017 Jun 12;9:35.
Title:	Prevalence of pks-positive Escherichia coli in Japanese patients with or without colorectal cancer.
Author:	Shimpoh, Takayuki\|Hirata, Yoshihiro\|Ihara, Sozaburo\|Suzuki, Nobumi\|Kinoshita, Hiroto\|Hayakawa, Yoku\|Ota, Yumiko\|Narita, Akiko\|Yoshida, Shuntaro\|Yamada, Atsuo\|Koike, Kazuhiko
PMID:	28616082

3073.
Journal:	J Clin Oncol. 2017 Aug 20;35(24):2806-2813.
Title:	Timing of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients With Colorectal Cancer in Relation to Tumor Markers and Survival.
Author:	Hua, Xinwei\|Phipps, Amanda I\|Burnett-Hartman, Andrea N\|Adams, Scott V\|Hardikar, Sheetal\|Cohen, Stacey A\|Kocarnik, Jonathan M\|Ahnen, Dennis J\|Lindor, Noralane M\|Baron, John A\|Newcomb, Polly A
PMID:	28617623

3074.
Journal:	JAMA Oncol. 2017 Nov 1;3(11):1546-1553.
Title:	Genomic Profiling of Small-Bowel Adenocarcinoma.
Author:	Schrock, Alexa B\|Devoe, Craig E\|McWilliams, Robert\|Sun, James\|Aparicio, Thomas\|Stephens, Philip J\|Ross, Jeffrey S\|Wilson, Richard\|Miller, Vincent A\|Ali, Siraj M\|Overman, Michael J
PMID:	28617917

3075.
Journal:	Mol Oncol. 2017 Sep;11(9):1263-1272.
Title:	Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.
Author:	Dienstmann, Rodrigo\|Elez, Elena\|Argiles, Guillem\|Matos, Ignacio\|Sanz-Garcia, Enrique\|Ortiz, Carolina\|Macarulla, Teresa\|Capdevila, Jaume\|Alsina, Maria\|Sauri, Tamara\|Verdaguer, Helena\|Vilaro, Marta\|Ruiz-Pace, Fiorella\|Viaplana, Cristina\|Garcia, Ariadna\|Land
PMID:	28618197

3076.
Journal:	Br J Cancer. 2017 Jul 25;117(3):358-366.
Title:	Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.
Author:	Mariani, Sara\|Bertero, Luca\|Osella-Abate, Simona\|Di Bello, Cristiana\|Francia di Celle, Paola\|Coppola, Vittoria\|Sapino, Anna\|Cassoni, Paola\|Marchio, Caterina
PMID:	28618430

3077.
Journal:	JAMA. 2017 Jun 20;317(23):2376-2378.
Title:	Cetuximab or Bevacizumab With First-Line Chemotherapy in Advanced KRAS Wild-Type Colorectal Cancer: No Difference, but Not the Same.
Author:	Lieu, Christopher H\|Messersmith, Wells A
PMID:	28632850

3078.
Journal:	Eur J Cancer. 2017 Aug;81:191-202.
Title:	First-line panitumumab plus FOLFOX4 or FOLFIRI in colorectal cancer with multiple or unresectable liver metastases: A randomised, phase II trial (PLANET-TTD).
Author:	Carrato, Alfredo\|Abad, Albert\|Massuti, Bartomeu\|Gravalos, Cristina\|Escudero, Pilar\|Longo-Munoz, Federico\|Manzano, Jose-Luis\|Gomez, Auxiliadora\|Safont, Maria Jose\|Gallego, Javier\|Garcia-Paredes, Beatriz\|Pericay, Carles\|Duenas, Rosario\|Rivera, Fernando\|Losa
PMID:	28633089

3079.
Journal:	PLoS One. 2017 Jun 21;12(6):e0178027.
Title:	SensiScreen(R)KRAS exon 2-sensitive simplex and multiplex real-time PCR-based assays for detection of KRAS exon 2 mutations.
Author:	Riva, Alice\|BOrgesen, Michael\|Guldmann-Christensen, Mariann\|Hauge Kyneb, Majbritt\|Voogd, Kirsten\|Andersen, Christina\|Epistolio, Samantha\|Merlo, Elisabetta\|Yding Wolff, Tine\|Hamilton-Dutoit, Stephen\|Lorenzen, Jan\|Christensen, Ulf Bech\|Frattini, Milo
PMID:	28636636

3080.
Journal:	Int J Med Sci. 2017 Apr 9;14(6):515-522.
Title:	Nuclear Expression of GS28 Protein: A Novel Biomarker that Predicts Prognosis in Colorectal Cancers.
Author:	Lee, Sung Hak\|Yoo, Hyung Jae\|Rim, Do Eun\|Cui, Yinji\|Lee, Ahwon\|Jung, Eun Sun\|Oh, Seung Taek\|Kim, Jun Gi\|Kwon, Oh-Joo\|Kim, Su Young\|Jeong, Seong-Whan
PMID:	28638266

3081.
Journal:	Mol Diagn Ther. 2017 Oct;21(5):571-579.
Title:	Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.
Author:	Ma, Wanlong\|Brodie, Steven\|Agersborg, Sally\|Funari, Vincent A\|Albitar, Maher
PMID:	28639239

3082.
Journal:	PLoS One. 2017 Jun 22;12(6):e0179510.
Title:	Bilateral blockade of MEK- and PI3K-mediated pathways downstream of mutant KRAS as a treatment approach for peritoneal mucinous malignancies.
Author:	Kuracha, Murali R\|Thomas, Peter\|Loggie, Brian W\|Govindarajan, Venkatesh
PMID:	28640835

3083.
Journal:	Clin Cancer Res. 2017 Oct 1;23(19):5936-5947.
Title:	Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.
Author:	Gausachs, Mireia\|Borras, Ester\|Chang, Kyle\|Gonzalez, Sara\|Azuara, Daniel\|Delgado Amador, Axel\|Lopez-Doriga, Adriana\|San Lucas, F Anthony\|Sanjuan, Xavier\|Paules, Maria J\|Taggart, Melissa W\|Davies, Gareth E\|Ehli, Erik A\|Fowler, Jerry\|Moreno, Victor\|Pineda,
PMID:	28645942

3084.
Journal:	In Vitro Cell Dev Biol Anim. 2017 Aug;53(7):575-578.
Title:	Application of open-access databases to determine functional connectivity between resveratrol-binding protein QR2 and colorectal carcinoma.
Author:	Doonan, Barbara B\|Schaafsma, Evelien\|Pinto, John T\|Wu, Joseph M\|Hsieh, Tze-Chen
PMID:	28646291

3085.
Journal:	Eur J Epidemiol. 2017 May;32(5):409-418.
Title:	Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.
Author:	Carr, Prudence R\|Jansen, Lina\|Bienert, Stefanie\|Roth, Wilfried\|Herpel, Esther\|Kloor, Matthias\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	28646407

3086.
Journal:	Int J Clin Oncol. 2017 Aug;22(4):651-659.
Title:	Targeting metabolic reprogramming in KRAS-driven cancers.
Author:	Kawada, Kenji\|Toda, Kosuke\|Sakai, Yoshiharu
PMID:	28647837

3087.
Journal:	In Vivo. 2017 Jul-Aug;31(4):527-542.
Title:	K-ras Mutations as the Earliest Driving Force in a Subset of Colorectal Carcinomas.
Author:	Margetis, Nikolaos\|Kouloukoussa, Myrsini\|Pavlou, Kyriaki\|Vrakas, Spyridon\|Mariolis-Sapsakos, Theodoros
PMID:	28652417

3088.
Journal:	Virchows Arch. 2017 Dec;471(6):721-729.
Title:	RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009-2016).
Author:	Richman, Susan D\|Fairley, Jennifer\|Butler, Rachel\|Deans, Zandra C
PMID:	28653203

3089.
Journal:	Mol Cancer. 2017 Jun 28;16(1):112.
Title:	PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation.
Author:	Tutuka, Candani S A\|Andrews, Miles C\|Mariadason, John M\|Ioannidis, Paul\|Hudson, Christopher\|Cebon, Jonathan\|Behren, Andreas
PMID:	28659148

3090.
Journal:	Int J Biol Markers. 2017 Oct 31;32(4):e474-e477.
Title:	Discordance in RAS mutations between primary colon tumor and metastases: a real event or a matter of methodology?
Author:	De Stefano, Alfonso\|Rosanova, Mario\|Malapelle, Umberto\|Martini, Maurizio\|De Falco, Stefano\|Attademo, Laura\|Fiore, Giovanni\|Cenci, Tonia\|Bellevicine, Claudio\|De Placido, Sabino\|Troncone, Giancarlo\|Carlomagno, Chiara
PMID:	28665451

3091.
Journal:	Anticancer Res. 2017 Jul;37(7):3817-3823.
Title:	Clinicopathological and Corresponding Genetic Features of Colorectal Signet Ring Cell Carcinoma.
Author:	Tajiri, Kensuke\|Sudou, Tomoya\|Fujita, Fumihiko\|Hisaka, Toru\|Kinugasa, Tetsushi\|Akagi, Yoshito
PMID:	28668881

3092.
Journal:	Anticancer Res. 2017 Jul;37(7):3833-3839.
Title:	Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS.
Author:	Nishi, Kensuke\|Luo, Hao\|Ishikura, Shuhei\|Doi, Keiko\|Iwaihara, Yuri\|Wills, Lauren\|Baillie, George S\|Sakata, Toshifumi\|Shirasawa, Senji\|Tsunoda, Toshiyuki
PMID:	28668883

3093.
Journal:	Anticancer Res. 2017 Jul;37(7):3855-3862.
Title:	An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.
Author:	Nishi, Kensuke\|Luo, Hao\|Nakabayashi, Kazuhiko\|Doi, Keiko\|Ishikura, Shuhei\|Iwaihara, Yuri\|Yoshida, Yasuhiro\|Tanisawa, Kumpei\|Arai, Tomio\|Mori, Seijiro\|Sawabe, Motoji\|Muramatsu, Masaaki\|Tanaka, Masashi\|Sakata, Toshifumi\|Shirasawa, Senji\|Tsunoda, Toshiyuki
PMID:	28668886

3094.
Journal:	Tumour Biol. 2017 Jul;39(7):1010428317709638.
Title:	Oncogene mutation profile predicts tumor regression and survival in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy and radical surgery.
Author:	Peng, Jianhong\|Lin, Junzhong\|Qiu, Miaozhen\|Zhao, Yujie\|Deng, Yuxiang\|Shao, Jianyong\|Ding, Peirong\|Zhang, Huizhong\|Wan, Desen\|Lu, Zhenhai\|Pan, Zhizhong
PMID:	28671043

3095.
Journal:	Mol Med Rep. 2017 Sep;16(3):2726-2732.
Title:	Wildtype blocking pcr coupled with internal competitive amplified fragment improved the detection of rare mutation of KRAS.
Author:	Peng, Jia\|Wei, Kun\|Zhao, Xiang\|Yang, Ke\|Wang, Huan\|Zhang, Yang\|Guo, Mei\|He, Jing\|Wu, Haiyan\|Li, Yongchuan\|Zhao, Na\|Huang, Qing\|Fu, Weiling
PMID:	28677778

3096.
Journal:	Int J Mol Sci. 2017 Jul 5;18(7). pii: ijms18071441.
Title:	Molecular and Clinicopathological Differences by Age at the Diagnosis of Colorectal Cancer.
Author:	Chang, Chu-Cheng\|Lin, Pei-Ching\|Lin, Chun-Chi\|Lan, Yuan-Tzu\|Lin, Hung-Hsin\|Lin, Chien-Hsing\|Yang, Shung-Haur\|Liang, Wen-Yi\|Chen, Wei-Shone\|Jiang, Jeng-Kai\|Lin, Jen-Kou\|Chang, Shih-Ching
PMID:	28678173

3097.
Journal:	Mol Clin Oncol. 2017 Jul;7(1):113-120.
Title:	Heterogeneity in the colorectal primary tumor and the synchronous resected liver metastases prior to and after treatment with an anti-EGFR monoclonal antibody.
Author:	Adua, Daniela\|Di Fabio, Francesca\|Ercolani, Giorgio\|Fiorentino, Michelangelo\|Gruppioni, Elisa\|Altimari, Annalisa\|Rojas Limpe, Fabiola Lorena\|Normanno, Nicola\|Pinna, Antonio Daniele\|Pinto, Carmine
PMID:	28685087

3098.
Journal:	Ann Surg Oncol. 2017 Nov;24(12):3587-3595.
Title:	A Multicenter Phase 2 Study on the Feasibility and Efficacy of Neoadjuvant Chemotherapy Without Radiotherapy for Locally Advanced Rectal Cancer.
Author:	Hasegawa, Suguru\|Goto, Saori\|Matsumoto, Takuya\|Hida, Koya\|Kawada, Kenji\|Matsusue, Ryo\|Yamaguchi, Takashi\|Nishitai, Ryuta\|Manaka, Dai\|Kato, Shigeru\|Kadokawa, Yoshio\|Yamanokuchi, Satoshi\|Kawamura, Junichiro\|Zaima, Masazumi\|Kyogoku, Takahisa\|Kanazawa, Akiyos
PMID:	28685354

3099.
Journal:	Oncol Lett. 2017 Jul;14(1):1109-1114.
Title:	Coffee reduces KRAS expression in Caco-2 human colon carcinoma cells via regulation of miRNAs.
Author:	Nakayama, Takuya\|Funakoshi-Tago, Megumi\|Tamura, Hiroomi
PMID:	28693281

3100.
Journal:	Int J Mol Epidemiol Genet. 2017 Jun 15;8(3):27-39. eCollection 2017.
Title:	Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect.
Author:	Zauber, Peter\|Marotta, Stephen\|Sabbath-Solitare, Marlene
PMID:	28694923

3101.
Journal:	Cancer Metastasis Rev. 2017 Jun;36(2):395-406.
Title:	Optimal use of anti-EGFR monoclonal antibodies for patients with advanced colorectal cancer: a meta-analysis.
Author:	van Helden, E J\|Menke-van der Houven van Oordt, C W\|Heymans, M W\|Ket, J C F\|van den Oord, R\|Verheul, H M W
PMID:	28695301

3102.
Journal:	Hell J Nucl Med. 2017 May-Aug;20(2):160-165.
Title:	The value of (18)FDG PET/CT parameters, hematological parameters and tumor markers in predicting KRAS oncogene mutation in colorectal cancer.
Author:	Oner, Ali Ozan\|Budak, Evrim Surer\|Yildirim, Senay\|Aydin, Funda\|Sezer, Cem
PMID:	28697193

3103.
Journal:	Int J Biol Markers. 2017 Oct 31;32(4):e434-e440.
Title:	Variations in transrenal DNA and comparison with plasma DNA as a diagnostic marker for colorectal cancer.
Author:	Tian, Fang\|Liao, Yuanfang\|Zhang, Yanfang
PMID:	28708207

3104.
Journal:	Cancer Chemother Pharmacol. 2017 Sep;80(3):527-533.
Title:	Clarithromycin co-administration does not increase irinotecan (CPT-11) toxicity in colorectal cancer patients.
Author:	Makihara, Katsuya\|Nakamura, Sayaka\|Miyagi, Kazuyo\|Ueno, Hiroyuki\|Nakata, Izumi
PMID:	28711984

3105.
Journal:	Cell Rep. 2017 Jul 25;20(4):999-1015.
Title:	A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Author:	Anderson, Grace R\|Winter, Peter S\|Lin, Kevin H\|Nussbaum, Daniel P\|Cakir, Merve\|Stein, Elizabeth M\|Soderquist, Ryan S\|Crawford, Lorin\|Leeds, Jim C\|Newcomb, Rachel\|Stepp, Priya\|Yip, Catherine\|Wardell, Suzanne E\|Tingley, Jennifer P\|Ali, Moiez\|Xu, Mengmeng\|Ry
PMID:	28746882

3106.
Journal:	Rev Med Chil. 2017 Apr;145(4):419-430.
Title:	[Characterization of patients with sporadic colorectal cancer following the new Consensus Molecular Subtypes (CMS)].
Author:	Wielandt, Ana Maria\|Villarroel, Cynthia\|Hurtado, Claudia\|Simian, Daniela\|Zamorano, Diego\|Martinez, Maripaz\|Castro, Magdalena\|Vial, Maria Teresa\|Kronberg, Udo\|Lopez-Kostner, Francisco
PMID:	28748988

3107.
Journal:	Int J Mol Sci. 2017 Jul 27;18(8). pii: ijms18081632.
Title:	Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer.
Author:	Toda, Kosuke\|Nishikawa, Gen\|Iwamoto, Masayoshi\|Itatani, Yoshiro\|Takahashi, Ryo\|Sakai, Yoshiharu\|Kawada, Kenji
PMID:	28749408

3108.
Journal:	Cell Biol Int. 2017 Oct;41(10):1127-1145.
Title:	Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients Vitamin C and niacin on colon cancer stem cells (CSCs).
Author:	Sen, Utsav\|Shenoy P, Sudheer\|Bose, Bipasha
PMID:	28755485

3109.
Journal:	Angew Chem Int Ed Engl. 2017 Sep 11;56(38):11539-11544.
Title:	A Quadruple-Action Platinum(IV) Prodrug with Anticancer Activity Against KRAS Mutated Cancer Cell Lines.
Author:	Petruzzella, Emanuele\|Braude, Jeremy Phillip\|Aldrich-Wright, Janice R\|Gandin, Valentina\|Gibson, Dan
PMID:	28759160

3110.
Journal:	Lancet Oncol. 2017 Sep;18(9):1172-1181.
Title:	TAS-102 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE): an investigator-initiated, open-label, single-arm, multicentre, phase 1/2 study.
Author:	Kuboki, Yasutoshi\|Nishina, Tomohiro\|Shinozaki, Eiji\|Yamazaki, Kentaro\|Shitara, Kohei\|Okamoto, Wataru\|Kajiwara, Takeshi\|Matsumoto, Toshihiko\|Tsushima, Takahiro\|Mochizuki, Nobuo\|Nomura, Shogo\|Doi, Toshihiko\|Sato, Akihiro\|Ohtsu, Atsushi\|Yoshino, Takayuki
PMID:	28760399

3111.
Journal:	Mol Cancer Ther. 2017 Nov;16(11):2340-2350.
Title:	A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Author:	Galban, Stefanie\|Apfelbaum, April A\|Espinoza, Carlos\|Heist, Kevin\|Haley, Henry\|Bedi, Karan\|Ljungman, Mats\|Galban, Craig J\|Luker, Gary D\|Dort, Marcian Van\|Ross, Brian D
PMID:	28775144

3112.
Journal:	Oncologist. 2017 Sep;22(9):1049-1055.
Title:	Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.
Author:	Spindler, Karen-Lise G\|Boysen, Anders K\|Pallisgard, Niels\|Johansen, Julia S\|Tabernero, Josep\|Sorensen, Morten M\|Jensen, Benny V\|Hansen, Torben F\|Sefrioui, David\|Andersen, Rikke F\|Brandslund, Ivan\|Jakobsen, Anders
PMID:	28778958

3113.
Journal:	Oncogene. 2017 Nov 23;36(47):6581-6591.
Title:	Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers.
Author:	Hata, A N\|Rowley, S\|Archibald, H L\|Gomez-Caraballo, M\|Siddiqui, F M\|Ji, F\|Jung, J\|Light, M\|Lee, J S\|Debussche, L\|Sidhu, S\|Sadreyev, R I\|Watters, J\|Engelman, J A
PMID:	28783173

3114.
Journal:	BMJ Case Rep. 2017 Aug 7;2017. pii: bcr-2017-220008.
Title:	Synovial metastasis of the knee in a KRAS mutant rectal adenocarcinoma patient.
Author:	Tapia Rico, Gonzalo\|Klevansky, Myron\|Townsend, Amanda\|Price, Timothy
PMID:	28784880

3115.
Journal:	J Biomol Tech. 2017 Sep;28(3):97-110.
Title:	Squirrel Primer-Based PCR Assay for Direct and Targeted Sanger Sequencing of Short Genomic Segments.
Author:	Ebili, Henry O\|Hassall, James C\|Fadhil, Wakkas\|Ham-Karim, Hersh\|Asiri, Abutaleb\|Raposo, Teresa P\|Agboola, Ayodeji Johnson\|Ilyas, Mohammad
PMID:	28785174

3116.
Journal:	Front Oncol. 2017 Jul 25;7:160.
Title:	Potential Role of Metabolic Intervention in the Management of Advanced Differentiated Thyroid Cancer.
Author:	Tella, Sri Harsha\|Kommalapati, Anuhya\|Esquivel, Mary Angelynne\|Correa, Ricardo
PMID:	28791253

3117.
Journal:	Ther Adv Med Oncol. 2017 Aug;9(8):551-564.
Title:	Recent developments in the treatment of metastatic colorectal cancer.
Author:	Loree, Jonathan M\|Kopetz, Scott
PMID:	28794806

3118.
Journal:	PLoS One. 2017 Aug 10;12(8):e0182562.
Title:	The prognostic value of KRAS mutation by cell-free DNA in cancer patients: A systematic review and meta-analysis.
Author:	Zhuang, Rongyuan\|Li, Song\|Li, Qian\|Guo, Xi\|Shen, Feng\|Sun, Hong\|Liu, Tianshu
PMID:	28796802

3119.
Journal:	Int J Mol Sci. 2017 Aug 11;18(8). pii: ijms18081746.
Title:	Phellinus linteus Grown on Germinated Brown Rice Increases Cetuximab Sensitivity of KRAS-Mutated Colon Cancer.
Author:	Park, Hye-Jin\|Park, Jeong-Bin\|Lee, Sang-Jae\|Song, Minjung
PMID:	28800074

3120.
Journal:	Sci Rep. 2017 Aug 11;7(1):7882.
Title:	Differences of protein expression profiles, KRAS and BRAF mutation, and prognosis in right-sided colon, left-sided colon and rectal cancer.
Author:	Gao, Xian Hua\|Yu, Guan Yu\|Gong, Hai Feng\|Liu, Lian Jie\|Xu, Yi\|Hao, Li Qiang\|Liu, Peng\|Liu, Zhi Hong\|Bai, Chen Guang\|Zhang, Wei
PMID:	28801584

3121.
Journal:	PLoS Genet. 2017 Aug 14;13(8):e1006942.
Title:	A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds.
Author:	Cairney, Claire J\|Godwin, Lauren S\|Bilsland, Alan E\|Burns, Sharon\|Stevenson, Katrina H\|McGarry, Lynn\|Revie, John\|Moore, Jon D\|Wiggins, Ceri M\|Collinson, Rebecca S\|Mudd, Clare\|Tsonou, Elpida\|Sadaie, Mahito\|Bennett, Dorothy C\|Narita, Masashi\|Torrance, Chris
PMID:	28806777

3122.
Journal:	J Immunother Cancer. 2017 Aug 15;5(1):63.
Title:	The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.
Author:	Poon, Edmund\|Mullins, Stefanie\|Watkins, Amanda\|Williams, Geoffrey S\|Koopmann, Jens-Oliver\|Di Genova, Gianfranco\|Cumberbatch, Marie\|Veldman-Jones, Margaret\|Grosskurth, Shaun E\|Sah, Vasu\|Schuller, Alwin\|Reimer, Corrine\|Dovedi, Simon J\|Smith, Paul D\|Stewart,
PMID:	28807001

3123.
Journal:	Case Rep Oncol Med. 2017;2017:2321052.
Title:	Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma.
Author:	Vittal, Anusha\|Middinti, Akshay\|Kasi Loknath Kumar, Anup
PMID:	28811946

3124.
Journal:	Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8234-E8243.
Title:	Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts.
Author:	Fior, Rita\|Povoa, Vanda\|Mendes, Raquel V\|Carvalho, Tania\|Gomes, Antonio\|Figueiredo, Nuno\|Ferreira, Miguel Godinho
PMID:	28835536

3125.
Journal:	Int J Mol Sci. 2017 Aug 29;18(9). pii: ijms18091871.
Title:	Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis.
Author:	Balc'h, Eric Le\|Grandin, Nathalie\|Demattei, Marie-Veronique\|Guyetant, Serge\|Tallet, Anne\|Pages, Jean-Christophe\|Ouaissi, Mehdi\|Lecomte, Thierry\|Charbonneau, Michel
PMID:	28850092

3126.
Journal:	Int J Cancer. 2017 Dec 15;141(12):2471-2479.
Title:	Tumor expression of calcium sensing receptor and colorectal cancer survival: Results from the nurses' health study and health professionals follow-up study.
Author:	Momen-Heravi, Fatemeh\|Masugi, Yohei\|Qian, Zhi Rong\|Nishihara, Reiko\|Liu, Li\|Smith-Warner, Stephanie A\|Keum, NaNa\|Zhang, Lanjing\|Tchrakian, Nairi\|Nowak, Jonathan A\|Yang, Wanshui\|Ma, Yanan\|Bowden, Michaela\|da Silva, Annacarolina\|Wang, Molin\|Fuchs, Charles S
PMID:	28856682

3127.
Journal:	Medicine (Baltimore). 2017 Sep;96(35):e7882.
Title:	Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer: Direct and indirect comparison meta-analysis.
Author:	Kwak, Min Seob\|Cha, Jae Myung\|Yoon, Jin Young\|Jeon, Jung Won\|Shin, Hyun Phil\|Chang, Hye Jung\|Kim, Hyung Kyung\|Joo, Kwang Ro\|Lee, Joung Il
PMID:	28858102

3128.
Journal:	Br J Cancer. 2017 Oct 24;117(9):1286-1294.
Title:	Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Author:	Gollins, Simon\|West, Nick\|Sebag-Montefiore, David\|Myint, Arthur Sun\|Saunders, Mark\|Susnerwala, Shabbir\|Quirke, Phil\|Essapen, Sharadah\|Samuel, Leslie\|Sizer, Bruce\|Worlding, Jane\|Southward, Katie\|Hemmings, Gemma\|Tinkler-Hundal, Emma\|Taylor, Morag\|Bottomley,
PMID:	28859058

3129.
Journal:	BMC Cancer. 2017 Sep 1;17(1):607.
Title:	Down-regulation of miRNA-148a and miRNA-625-3p in colorectal cancer is associated with tumor budding.
Author:	Baltruskeviciene, Edita\|Schveigert, Diana\|Stankevicius, Vaidotas\|Mickys, Ugnius\|Zvirblis, Tadas\|Bublevic, Jaroslav\|Suziedelis, Kestutis\|Aleknavicius, Eduardas
PMID:	28863773

3130.
Journal:	Diagnostics (Basel). 2017 Sep 2;7(3). pii: diagnostics7030050.
Title:	Using Naive Bayesian Analysis to Determine Imaging Characteristics of KRAS Mutations in Metastatic Colon Cancer.
Author:	Pershad, Yash\|Govindan, Siddharth\|Hara, Amy K\|Borad, Mitesh J\|Bekaii-Saab, Tanios\|Wallace, Alex\|Albadawi, Hassan\|Oklu, Rahmi
PMID:	28869500

3131.
Journal:	Cancer Genomics Proteomics. 2017 Sep-Oct;14(5):341-348.
Title:	Colitic Cancer Develops Through Mutational Alteration Distinct from that in Sporadic Colorectal Cancer: A Comparative Analysis of Mutational Rates at Each Step.
Author:	Tanaka, Toshiaki\|Kobunai, Takashi\|Yamamoto, Yoko\|Emoto, Shigenobu\|Murono, Koji\|Kaneko, Manabu\|Sasaki, Kazuhito\|Otani, Kensuke\|Nishikawa, Takeshi\|Kawai, Kazushige\|Hata, Keisuke\|Nozawa, Hiroaki\|Watanabe, Toshiaki
PMID:	28871001

3132.
Journal:	Oncotarget. 2017 Jul 5;8(32):53631-53641.
Title:	The impact of primary tumor location on efficacy of cetuximab in metastatic colorectal cancer patients with different Kras status: a systematic review and meta-analysis.
Author:	Cao, De-Dong\|Xu, Hui-Lin\|Xu, Xi-Ming\|Ge, Wei
PMID:	28881837

3133.
Journal:	Int J Biol Markers. 2017 Oct 31;32(4):e421-e427.
Title:	Circulating tumor DNA is effective for detection of KRAS mutation in colorectal cancer: a meta-analysis.
Author:	Tang, Min\|Deng, Zhenghua\|Li, Baolin\|Peng, Ying\|Song, Min\|Liu, Jinbo
PMID:	28885658

3134.
Journal:	Pragmat Obs Res. 2017 Aug 26;8:149-155.
Title:	A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data.
Author:	Kern, David M\|Barron, John J\|Wu, Bingcao\|Ganetsky, Alex\|Willey, Vincent J\|Quimbo, Ralph A\|Fisch, Michael J\|Singer, Joseph\|Nguyen, Ann\|Mamtani, Ronac
PMID:	28894396

3135.
Journal:	Oncotarget. 2017 Jun 14;8(34):57845-57854.
Title:	Implementation and utilization of the molecular tumor board to guide precision medicine.
Author:	Harada, Shuko\|Arend, Rebecca\|Dai, Qian\|Levesque, Jessica A\|Winokur, Thomas S\|Guo, Rongjun\|Heslin, Martin J\|Nabell, Lisle\|Nabors, L Burt\|Limdi, Nita A\|Roth, Kevin A\|Partridge, Edward E\|Siegal, Gene P\|Yang, Eddy S
PMID:	28915716

3136.
Journal:	Cancer Res. 2017 Nov 1;77(21):5741-5754.
Title:	Upregulation of Cystathionine-beta-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.
Author:	Phillips, Ches'Nique M\|Zatarain, John R\|Nicholls, Michael E\|Porter, Craig\|Widen, Steve G\|Thanki, Ketan\|Johnson, Paul\|Jawad, Muhammad U\|Moyer, Mary P\|Randall, James W\|Hellmich, Judith L\|Maskey, Manjit\|Qiu, Suimin\|Wood, Thomas G\|Druzhyna, Nadiya\|Szczesny, B
PMID:	28923859

3137.
Journal:	J Cancer. 2017 Aug 23;8(14):2809-2815.
Title:	The Impact of Microsatellite Instability Status and Sidedness of the Primary Tumor on the Effect of Cetuximab-Containing Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author:	Kim, Seung Tae\|Lee, Su-Jin\|Lee, Jeeyun\|Park, Se Hoon\|Park, Joon Oh\|Lim, Ho Yeong\|Kang, Won Ki\|Park, Young Suk
PMID:	28928870

3138.
Journal:	Sci Rep. 2017 Sep 20;7(1):12020.
Title:	Ex vivo treatment of patient biopsies as a novel method to assess colorectal tumour response to the MEK1/2 inhibitor, Selumetinib.
Author:	Novo, Sonia M\|Wedge, Stephen R\|Stark, Lesley A
PMID:	28931905

3139.
Journal:	World J Gastroenterol. 2017 Aug 28;23(32):5913-5924.
Title:	Integrating TYMS, KRAS and BRAF testing in patients with metastatic colorectal cancer.
Author:	Ntavatzikos, Anastasios\|Spathis, Aris\|Patapis, Paul\|Machairas, Nikolaos\|Peros, George\|Konstantoudakis, Stefanos\|Leventakou, Danai\|Panayiotides, Ioannis G\|Karakitsos, Petros\|Koumarianou, Anna
PMID:	28932083

3140.
Journal:	Tumour Biol. 2017 Sep;39(9):1010428317724517.
Title:	EGFR pathway subgroups in Chilean colorectal cancer patients, detected by mutational and expression profiles, associated to different clinicopathological features.
Author:	Alvarez, Karin\|Orellana, Paulina\|Villarroel, Cynthia\|Contreras, Luis\|Kawachi, Hiroshi\|Kobayashi, Maki\|Wielandt, Ana Maria\|De la Fuente, Marjorie\|Trivino, Juan Carlos\|Kronberg, Udo\|Carvallo, Pilar\|Lopez-Kostner, Francisco
PMID:	28936923

3141.
Journal:	Clin Cancer Res. 2017 Dec 1;23(23):7209-7216.
Title:	Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer.
Author:	Joung, Je-Gun\|Oh, Bo Young\|Hong, Hye Kyung\|Al-Khalidi, Hisham\|Al-Alem, Faisal\|Lee, Hae-Ock\|Bae, Joon Seol\|Kim, Jinho\|Cha, Hong-Ui\|Alotaibi, Maram\|Cho, Yong Beom\|Hassanain, Mazen\|Park, Woong-Yang\|Lee, Woo Yong
PMID:	28939741

3142.
Journal:	Cancer Lett. 2017 Dec 1;410:92-99.
Title:	Major challenges related to tumor biological characteristics in accurate mutation detection of colorectal cancer by next-generation sequencing.
Author:	Li, Weihua\|Qiu, Tian\|Guo, Lei\|Ying, Jianming
PMID:	28942013

3143.
Journal:	Cancer Lett. 2017 Dec 1;410:139-157.
Title:	Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.
Author:	Yagdi Efe, Esma\|Mazumder, Aloran\|Lee, Jin-Young\|Gaigneaux, Anthoula\|Radogna, Flavia\|Nasim, Muhammad Jawad\|Christov, Christo\|Jacob, Claus\|Kim, Kyu-Won\|Dicato, Mario\|Chaimbault, Patrick\|Cerella, Claudia\|Diederich, Marc
PMID:	28943451

3144.
Journal:	Cancer Res. 2017 Nov 15;77(22):6330-6339.
Title:	Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.
Author:	Yau, Edwin H\|Kummetha, Indrasena Reddy\|Lichinchi, Gianluigi\|Tang, Rachel\|Zhang, Yunlin\|Rana, Tariq M
PMID:	28954733

3145.
Journal:	PLoS One. 2017 Sep 28;12(9):e0185607.
Title:	High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.
Author:	Coebergh van den Braak, Robert R J\|Sieuwerts, Anieta M\|Kandimalla, Raju\|Lalmahomed, Zarina S\|Bril, Sandra I\|van Galen, Anne\|Smid, Marcel\|Biermann, Katharina\|van Krieken, J Han J M\|Kloosterman, Wigard P\|Foekens, John A\|Goel, Ajay\|Martens, John W M\|IJzerman
PMID:	28957395

3146.
Journal:	Case Rep Oncol. 2017 Aug 23;10(2):777-782.
Title:	What Is Different in the Population of the Brazilian Amazon Region so that They Have a Low Frequency of KRAS Gene Mutations?
Author:	de Carvalho, Luis Eduardo W\|Sarraf, Jonathan S\|Oliveira, Ana Carolina M\|Neto, Nilson D B\|Camara, Thiago F\|Fonseca, Fernando Luiz A\|Adami, Fernando
PMID:	28966582

3147.
Journal:	Oncotarget. 2017 Jul 10;8(40):68026-68037.
Title:	Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Author:	Kong, Say Li\|Liu, Xingliang\|Suhaimi, Nur-Afidah Mohamed\|Koh, Kenneth Jia Hao\|Hu, Min\|Lee, Daniel Yoke San\|Cima, Igor\|Phyo, Wai Min\|Lee, Esther Xing Wei\|Tai, Joyce A\|Foong, Yu Miin\|Vo, Jess Honganh\|Koh, Poh Koon\|Zhang, Tong\|Ying, Jackie Y\|Lim, Bing\|Tan, Mi
PMID:	28978093

3148.
Journal:	Am J Cancer Res. 2017 Sep 1;7(9):1978-1989. eCollection 2017.
Title:	KRAS mutation status is highly homogeneous between areas of the primary tumor and the corresponding metastasis of colorectal adenocarcinomas: one less problem in patient care.
Author:	Petaccia de Macedo, Mariana\|Melo, Fernanda M\|Ribeiro, Heber Salvador C\|Marques, Marcio C\|Kagohara, Luciane T\|Begnami, Maria Dirlei\|Neto, Julio C\|Ribeiro, Julia S\|Soares, Fernando A\|Carraro, Dirce M\|Cunha, Isabela W
PMID:	28979819

3149.
Journal:	PLoS One. 2017 Oct 5;12(10):e0175484.
Title:	Neutral evolution of drug resistant colorectal cancer cell populations is independent of their KRAS status.
Author:	Blagoev, Krastan B\|Wilkerson, Julia\|Burotto, Mauricio\|Kim, Chul\|Espinal-Dominguez, Edward\|Garcia-Alfonso, Pilar\|Alimchandani, Meghna\|Miettinen, Markku\|Blanco-Codesido, Montserrat\|Fojo, Tito
PMID:	28981524

3150.
Journal:	Br J Cancer. 2017 Dec 5;117(12):1819-1827.
Title:	Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.
Author:	Lievre, Astrid\|Ouine, Berengere\|Canet, Jim\|Cartier, Aurelie\|Amar, Yael\|Cacheux, Wulfran\|Mariani, Odette\|Guimbaud, Rosine\|Selves, Janick\|Lecomte, Thierry\|Guyetant, Serge\|Bieche, Ivan\|Berger, Frederique\|de Koning, Leanne
PMID:	29024937

3151.
Journal:	Oncotarget. 2017 Apr 11;8(39):64999-65008.
Title:	Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment.
Author:	Moorcraft, Sing Y\|Jones, Thomas\|Walker, Brian A\|Ladas, George\|Kalaitzaki, Eleftheria\|Yuan, Lina\|Begum, Ruwaida\|Eltahir, Zakaria\|Wotherspoon, Andrew\|Montero-Fernandez, Angeles\|Teixeira Mendes, Larissa S\|Gonzalez de Castro, David\|Wilson, Sanna Hulkki\|Prosze
PMID:	29029407

3152.
Journal:	Oncotarget. 2017 May 10;8(39):65090-65099.
Title:	Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.
Author:	Dosch, Joseph\|Ziemke, Elizabeth\|Wan, Shanshan\|Luker, Kathryn\|Welling, Theodore\|Hardiman, Karin\|Fearon, Eric\|Thomas, Suneetha\|Flynn, Matthew\|Rios-Doria, Jonathan\|Hollingsworth, Robert\|Herbst, Ronald\|Hurt, Elaine\|Sebolt-Leopold, Judith
PMID:	29029414

3153.
Journal:	Oncotarget. 2017 Jun 20;8(39):65407-65413.
Title:	Colorectal carcinoma with osseous metaplasia.
Author:	Liu, Xibo\|Xu, Jinghong\|Chen, Lirong
PMID:	29029440

3154.
Journal:	Oncotarget. 2017 Aug 11;8(39):66458-66466.
Title:	Targeted first-line therapies for advanced colorectal cancer: a Bayesian meta-analysis.
Author:	Ridouane, Yassine\|Lopes, Gilberto\|Ku, Geoffrey\|Masud, Hasan\|Haaland, Benjamin
PMID:	29029527

3155.
Journal:	Chin J Cancer. 2017 Oct 16;36(1):81.
Title:	Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study.
Author:	Wang, Xicheng\|Wei, Qing\|Gao, Jing\|Li, Jian\|Li, Jie\|Gong, Jifang\|Li, Yanyan\|Shen, Lin
PMID:	29037218

3156.
Journal:	Cancer Immunol Res. 2017 Nov;5(11):1046-1055.
Title:	Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer.
Author:	Masugi, Yohei\|Nishihara, Reiko\|Hamada, Tsuyoshi\|Song, Mingyang\|da Silva, Annacarolina\|Kosumi, Keisuke\|Gu, Mancang\|Shi, Yan\|Li, Wanwan\|Liu, Li\|Nevo, Daniel\|Inamura, Kentaro\|Cao, Yin\|Liao, Xiaoyun\|Nosho, Katsuhiko\|Chan, Andrew T\|Giannakis, Marios\|Bass, Adam
PMID:	29038297

3157.
Journal:	Clin Transl Gastroenterol. 2017 Oct 19;8(10):e124.
Title:	Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer.
Author:	Staudacher, Jonas J\|Yazici, Cemal\|Bul, Vadim\|Zeidan, Joseph\|Khalid, Ahmer\|Xia, Yinglin\|Krett, Nancy\|Jung, Barbara
PMID:	29048416

3158.
Journal:	Mutagenesis. 2017 Oct 17;32(5):533-542.
Title:	MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.
Author:	Schneiderova, Michaela\|Naccarati, Alessio\|Pardini, Barbara\|Rosa, Fabio\|Gaetano, Cornelia Di\|Jiraskova, Katerina\|Opattova, Alena\|Levy, Miroslav\|Veskrna, Karel\|Veskrnova, Veronika\|Buchler, Tomas\|Landi, Stefano\|Vodicka, Pavel\|Vymetalkova, Veronika
PMID:	29048575

3159.
Journal:	Oncol Rep. 2017 Nov;38(5):3187-3196.
Title:	MicroRNA337 inhibits colorectal cancer progression by directly targeting KRAS and suppressing the AKT and ERK pathways.
Author:	Liu, Xuerong\|Wang, Yan\|Zhao, Jinglong
PMID:	29048669

3160.
Journal:	Gan To Kagaku Ryoho. 2017 Oct;44(10):947-949.
Title:	[Anti-EGFR Antibody Combination Chemotherapy Was Effective against Locally Advanced Ascending Colon Cancer as Well as a Recurrent Lesion - A Case Report].
Author:	Yamada, Yasufumi\|Yokomizo, Hajime\|Yano, Yuki\|Okayama, Sachiyo\|Satake, Masaya\|Ida, Arika\|Usui, Takebumi\|Yamaguchi, Kentaro\|Shiozawa, Shunichi\|Yoshimatsu, Kazuhiko\|Shimakawa, Takeshi\|Katsube, Takao\|Naritaka, Yoshihiko\|Kato, Hiroyuki
PMID:	29066705

3161.
Journal:	Target Oncol. 2017 Dec;12(6):775-785.
Title:	A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer.
Author:	Wainberg, Zev A\|Alsina, Maria\|Soares, Heloisa P\|Brana, Irene\|Britten, Carolyn D\|Del Conte, Gianluca\|Ezeh, Patrick\|Houk, Brett\|Kern, Kenneth A\|Leong, Stephen\|Pathan, Nuzhat\|Pierce, Kristen J\|Siu, Lillian L\|Vermette, Jennifer\|Tabernero, Josep
PMID:	29067643

3162.
Journal:	Oncotarget. 2017 Aug 21;8(42):72352-72362.
Title:	Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer.
Author:	Chang, Pi-Yueh\|Chen, Jinn-Shiun\|Chang, Shih-Cheng\|Wang, Mei-Chia\|Chang, Nai-Chung\|Wen, Ying-Hao\|Tsai, Wen-Sy\|Liu, Wei-Hsiu\|Liu, Hsiu-Ling\|Lu, Jang-Jih
PMID:	29069792

3163.
Journal:	Cancer Med. 2017 Dec;6(12):2966-2971.
Title:	POLE somatic mutations in advanced colorectal cancer.
Author:	Guerra, Joana\|Pinto, Carla\|Pinto, Diana\|Pinheiro, Manuela\|Silva, Romina\|Peixoto, Ana\|Rocha, Patricia\|Veiga, Isabel\|Santos, Catarina\|Santos, Rui\|Cabreira, Veronica\|Lopes, Paula\|Henrique, Rui\|Teixeira, Manuel R
PMID:	29072370

3164.
Journal:	Sci Rep. 2017 Oct 30;7(1):14368.
Title:	KRAS mutation and primary tumor location do not affect efficacy of bevacizumab-containing chemotherapy in stagae IV colorectal cancer patients.
Author:	Sun, De-Cong\|Shi, Yan\|Wang, Yan-Rong\|Lv, Yao\|Yan, Huan\|Mao, Hui\|Wang, Zhi-Kuan\|Wu, Zhi-Yong\|Shi, Wei-Wei\|Dai, Guang-Hai
PMID:	29085005

3165.
Journal:	J Pathol Clin Res. 2017 Oct 7;3(4):268-278.
Title:	Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression.
Author:	Inaguma, Shingo\|Lasota, Jerzy\|Felisiak-Golabek, Anna\|Kowalik, Artur\|Wang, Zengfeng\|Zieba, Sebastian\|Kalisz, Joanna\|Ikeda, Hiroshi\|Miettinen, Markku
PMID:	29085667

3166.
Journal:	World J Gastroenterol. 2017 Oct 21;23(39):7087-7097.
Title:	Detection of KRAS G12D in colorectal cancer stool by droplet digital PCR.
Author:	Olmedillas-Lopez, Susana\|Levano-Linares, Dennis Cesar\|Alexandre, Carmen Laura Auz\|Vega-Clemente, Luz\|Sanchez, Edurne Leon\|Villagrasa, Alejandro\|Ruiz-Tovar, Jaime\|Garcia-Arranz, Mariano\|Garcia-Olmo, Damian
PMID:	29093617

3167.
Journal:	Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title:	Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author:	Jung, Joohee\|Kim, Jisup\|Lim, Hyun Kyung\|Kim, Kyoung Mee\|Lee, Yun Sun\|Park, Joon Seong\|Yoon, Dong Sup
PMID:	29094026

3168.
Journal:	Curr Probl Cancer. 2017 Nov - Dec;41(6):388-397.
Title:	Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.
Author:	Nejadtaghi, Mahdieh\|Jafari, Hamideh\|Farrokhi, Effat\|Samani, Keihan Ghatreh
PMID:	29096939

3169.
Journal:	Oncotarget. 2017 May 26;8(44):77928-77941.
Title:	Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients.
Author:	Liu, Yong\|Meucci, Stefano\|Sheng, Liming\|Keilholz, Ulrich
PMID:	29100436

3170.
Journal:	Clin Chim Acta. 2017 Oct 27. pii: S0009-8981(17)30422-9.
Title:	Real-time PCR-based method for the rapid detection of extended RAS mutations using bridged nucleic acids in colorectal cancer.
Author:	Iida, Takao\|Mizuno, Yukie\|Kaizaki, Yasuharu
PMID:	29111094

3171.
Journal:	BMC Cancer. 2017 Nov 7;17(1):723.
Title:	microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer.
Author:	Takahashi, Hidekazu\|Takahashi, Masanobu\|Ohnuma, Shinobu\|Unno, Michiaki\|Yoshino, Yuki\|Ouchi, Kota\|Takahashi, Shin\|Yamada, Yasuhide\|Shimodaira, Hideki\|Ishioka, Chikashi
PMID:	29115941

3172.
Journal:	Pathol Oncol Res. 2017 Nov 10. pii: 10.1007/s12253-017-0344-x.
Title:	Immunohistochemistry with Anti-BRAF V600E (VE1) Mouse Monoclonal Antibody is a Sensitive Method for Detection of the BRAF V600E Mutation in Colon Cancer: Evaluation of 120 Cases with and without KRAS Mutation and Literature Review.
Author:	Dvorak, Katerina\|Higgins, Amanda\|Palting, John\|Cohen, Michael\|Brunhoeber, Patrick
PMID:	29127628

3173.
Journal:	Oncotarget. 2017 Aug 8;8(48):83860-83871.
Title:	Rapid and accurate detection of KRAS mutations in colorectal cancers using the isothermal-based optical sensor for companion diagnostics.
Author:	Jin, Choong Eun\|Yeom, Seung-Seop\|Koo, Bonhan\|Lee, Tae Yoon\|Lee, Jeong Hoon\|Shin, Yong\|Lim, Seok-Byung
PMID:	29137388

3174.
Journal:	BMC Cancer. 2017 Nov 14;17(1):765.
Title:	Analysis of factors influencing molecular testing at diagnostic of colorectal cancer.
Author:	Thiebault, Quentin\|Defossez, Gautier\|Karayan-Tapon, Lucie\|Ingrand, Pierre\|Silvain, Christine\|Tougeron, David
PMID:	29137623

3175.
Journal:	Drug Resist Updat. 2017 Nov;33-35:36-42.
Title:	TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy.
Author:	Santoro, Raffaela\|Carbone, Carmine\|Piro, Geny\|Chiao, Paul J\|Melisi, Davide
PMID:	29145973

3176.
Journal:	Oncotarget. 2017 Sep 21;8(49):86253-86263.
Title:	Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR.
Author:	Kloten, Vera\|Ruchel, Nadine\|Bruchle, Nadina Ortiz\|Gasthaus, Janina\|Freudenmacher, Nils\|Steib, Florian\|Mijnes, Jolein\|Eschenbruch, Julian\|Binnebosel, Marcel\|Knuchel, Ruth\|Dahl, Edgar
PMID:	29156792

3177.
Journal:	Braz J Med Biol Res. 2017 Nov 13;51(1):e6472.
Title:	Exosomes promote cetuximab resistance via the PTEN/Akt pathway in colon cancer cells.
Author:	Zhang, S\|Zhang, Y\|Qu, J\|Che, X\|Fan, Y\|Hou, K\|Guo, T\|Deng, G\|Song, N\|Li, C\|Wan, X\|Qu, X\|Liu, Y
PMID:	29160412

3178.
Journal:	BMC Gastroenterol. 2017 Nov 23;17(1):121.
Title:	Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer.
Author:	Kim, Dalyong\|Kim, Sun Young\|Lee, Ji Sung\|Hong, Yong Sang\|Kim, Jeong Eun\|Kim, Kyu-Pyo\|Kim, Jihun\|Jang, Se Jin\|Yoon, Young-Kwang\|Kim, Tae Won
PMID:	29169325

3179.
Journal:	BMC Cancer. 2017 Nov 28;17(1):798.
Title:	Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review.
Author:	Han van Krieken, J\|Kafatos, George\|Bennett, James\|Mineur, Laurent\|Tomasek, Jiri\|Rouleau, Etienne\|Fabian, Pavel\|De Maglio, Giovanna\|Garcia-Alfonso, Pilar\|Aprile, Giuseppe\|Parkar, Parijan\|Downey, Gerald\|Demonty, Gaston\|Trojan, Jorg
PMID:	29183279

3180.
Journal:	Ann Biol Clin (Paris). 2017 Dec 1;75(6):607-618.
Title:	Detection of RAS mutations in circulating tumor cells: applications in colorectal cancer and prospects.
Author:	Denis, Jerome Alexandre\|Lacorte, Jean-Marc
PMID:	29192596

3181.
Journal:	Fukushima J Med Sci. 2017 Dec 19;63(3):141-151.
Title:	TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.
Author:	Ando, Jin\|Saito, Motonobu\|Imai, Jun-Ichi\|Ito, Emi\|Yanagisawa, Yuka\|Honma, Reiko\|Saito, Katsuharu\|Tachibana, Kazunoshin\|Momma, Tomoyuki\|Ohki, Shinji\|Ohtake, Tohru\|Watanabe, Shinya\|Waguri, Satoshi\|Kono, Koji\|Takenoshita, Seiichi
PMID:	29199261

3182.
Journal:	Heliyon. 2017 Nov 21;3(11):e00448.
Title:	KRAS biomarker testing disparities in colorectal cancer patients in New Mexico.
Author:	Greenbaum, Alissa\|Wiggins, Charles\|Meisner, Angela Lw\|Rojo, Manuel\|Kinney, Anita Y\|Rajput, Ashwani
PMID:	29202108

3183.
Journal:	Indian J Surg Oncol. 2017 Dec;8(4):511-513.
Title:	Patterns and the Occurrence of KRAS Mutations in Metastatic Colorectal Cancers-a Study from Indian Regional Cancer Centre.
Author:	Smitha, C S\|Suresh, Babu M C\|Linu, J A\|Lakshmaiah, K C\|Govind, Babu K\|Lokanatha, D\|Pretesh, R K
PMID:	29203982

3184.
Journal:	Oncotarget. 2017 Aug 24;8(55):93567-93579.
Title:	Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.
Author:	Shimada, Yoshifumi\|Kameyama, Hitoshi\|Nagahashi, Masayuki\|Ichikawa, Hiroshi\|Muneoka, Yusuke\|Yagi, Ryoma\|Tajima, Yosuke\|Okamura, Takuma\|Nakano, Masato\|Sakata, Jun\|Kobayashi, Takashi\|Nogami, Hitoshi\|Maruyama, Satoshi\|Takii, Yasumasa\|Hayashida, Tetsu\|Takaishi
PMID:	29212173

3185.
Journal:	Oncotarget. 2017 Sep 27;8(55):93856-93866.
Title:	Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: a post-hoc analysis of the New EPOC trial.
Author:	Pugh, Sian\|Thiebaut, Raphaele\|Bridgewater, John\|Grisoni, Marie-Lise\|Moutasim, Karwan\|Rousseau, Francis\|Thomas, Gareth J\|Griffiths, Gareth\|Liebaert, Francois\|Primrose, John\|Laurent-Puig, Pierre
PMID:	29212194

3186.
Journal:	Hered Cancer Clin Pract. 2017 Nov 29;15:22.
Title:	Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).
Author:	Horpaopan, Sukanya\|Kirfel, Jutta\|Peters, Sophia\|Kloth, Michael\|Huneburg, Robert\|Altmuller, Janine\|Drichel, Dmitriy\|Odenthal, Margarete\|Kristiansen, Glen\|Strassburg, Christian\|Nattermann, Jacob\|Hoffmann, Per\|Nurnberg, Peter\|Buttner, Reinhard\|Thiele, Holger
PMID:	29213343

3187.
Journal:	Nat Commun. 2017 Dec 8;8(1):1998.
Title:	Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.
Author:	Baker, Ann-Marie\|Huang, Weini\|Wang, Xiao-Ming Mindy\|Jansen, Marnix\|Ma, Xiao-Jun\|Kim, Jeffrey\|Anderson, Courtney M\|Wu, Xingyong\|Pan, Liuliu\|Su, Nan\|Luo, Yuling\|Domingo, Enric\|Heide, Timon\|Sottoriva, Andrea\|Lewis, Annabelle\|Beggs, Andrew D\|Wright, Nicholas
PMID:	29222441

3188.
Journal:	J Natl Compr Canc Netw. 2017 Dec;15(12):1484-1493.
Title:	KRAS Testing, Tumor Location, and Survival in Patients With Stage IV Colorectal Cancer: SEER 2010-2013.
Author:	Charlton, Mary E\|Kahl, Amanda R\|Greenbaum, Alissa A\|Karlitz, Jordan J\|Lin, Chi\|Lynch, Charles F\|Chen, Vivien W
PMID:	29223986

3189.
Journal:	Oncotarget. 2017 Sep 20;8(60):101333-101344.
Title:	LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer.
Author:	Li, Xiaona\|Chung, Arthur C K\|Li, Shangfu\|Wu, Lilan\|Xu, Jiaying\|Yu, Jun\|Wong, Chichun\|Cai, Zongwei
PMID:	29254168

3190.
Journal:	Oncotarget. 2017 Oct 19;8(61):103952-103967.
Title:	Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism.
Author:	Kashif, Muhammad\|Andersson, Claes\|Mansoori, Sharmineh\|Larsson, Rolf\|Nygren, Peter\|Gustafsson, Mats G
PMID:	29262612

3191.
Journal:	Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Dec 18;49(6):931-936.
Title:	[Mechanism of cross talk between tissue factor/active coagulation factor VII and epidermal growth factor receptor signalings in colon cancer cells in culture].
Author:	Chen, H K\|Dai, Y\|Wu, T\|Wang, X\|Wan, Y L\|Tang, J Q
PMID:	29263461

3192.
Journal:	Case Rep Oncol. 2017 Nov 20;10(3):1029-1034.
Title:	Long-Term Survival with Regorafenib in KRAS-Mutated Metastatic Rectal Cancer.
Author:	Amram, Marie-Laure\|Montet, Xavier\|Roth, Arnaud D
PMID:	29279709

3193.
Journal:	G Chir. 2017 Sep-Oct;38(5):213-218.
Title:	Study of the role of telomerase in colorectal cancer: preliminary report and literature review.
Author:	Minafra, M\|Laforgia, R\|Sederino, M G\|Fedele, S\|Delvecchio, A\|Lattarulo, S\|Carbotta, G\|Fabiano, G
PMID:	29280699

3194.
Journal:	Oncotarget. 2017 Sep 27;8(62):105072-105080.
Title:	Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine.
Author:	Hou, Helei\|Liu, Dong\|Zhang, Chuantao\|Jiang, Yanxia\|Lu, Guifang\|Zhou, Na\|Yang, Xiaonan\|Zhang, Xiaoping\|Li, Zhuokun\|Zhu, Hongmei\|Qian, Zhaoyang\|Zhang, Xiaochun
PMID:	29285234

3195.
Journal:	Cancer Biol Med. 2017 Nov;14(4):371-376.
Title:	Brain metastasis in advanced colorectal cancer: results from the South Australian metastatic colorectal cancer (SAmCRC) registry.
Author:	Tapia Rico, Gonzalo\|Price, Timothy J\|Karapetis, Christos\|Piantadosi, Cynthia\|Padbury, Rob\|Roy, Amitesh\|Maddern, Guy\|Moore, James\|Carruthers, Scott\|Roder, David\|Townsend, Amanda R
PMID:	29372103

3196.
Journal:	Gan To Kagaku Ryoho. 2017 Nov;44(12):1126-1128.
Title:	[A Case of Ascending Colon Cancer with Synchronous Liver Metastases and Peritoneal Dissemination].
Author:	Mito, Masato\|Kameyama, Hitoshi\|Shimada, Yoshifumi\|Yamada, Saki\|Hotta, Shinnosuke\|Hirose, Yuki\|Yagi, Ryoma\|Tajima, Yosuke\|Nakano, Mae\|Okamura, Takuma\|Nakano, Masato\|Ichikawa, Hiroshi\|Nagahashi, Masayuki\|Sakata, Jun\|Wakai, Toshifumi
PMID:	29394555

3197.
Journal:	Gan To Kagaku Ryoho. 2017 Nov;44(12):1420-1422.
Title:	[Case Report of Long-Term Survival for Stage IV Advanced Sigmoid Colon Cancer with Para-Aortic Nodes by R0 Resection and Chemotherapy].
Author:	Akai, Masaaki\|Otsuka, Shinya\|Yasui, Yuichi\|Isoda, Kenta\|Hamano, Ryousuke\|Tokunaga, Naoyuki\|Takahashi, Kenji\|Miyaso, Hideaki\|Tsunemitsu, Yousuke\|Iwakawa, Kazuhide\|Inagaki, Masaru\|Iwagaki, Hiromi
PMID:	29394654

3198.
Journal:	Tumori. 2017 Dec 1:tj5000701.
Title:	Increased Efficacy of Stereotactic Ablative Radiation Therapy after Bevacizumab in Lung Oligometastases from Colon Cancer.
Author:	Mazzola, Rosario\|Tebano, Umberto\|Aiello, Dario\|Di Paola, Gioacchino\|Giaj-Levra, Niccolo\|Ricchetti, Francesco\|Fersino, Sergio\|Fiorentino, Alba\|Ruggieri, Ruggero\|Alongi, Filippo
PMID:	29737958

3199.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Feb;26(2):140-146.
Title:	The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Author:	Skalova, Alena\|Sar, Aylin\|Laco, Jan\|Metelkova, Alena\|Miesbauerova, Marketa\|Steiner, Petr\|Svajdler, Marian\|Michal, Michal
PMID:	27258560

3200.
Journal:	J Gastrointest Cancer. 2018 Jun;49(2):124-131.
Title:	Clinicopathological Associations of K-RAS and N-RAS Mutations in Indonesian Colorectal Cancer Cohort.
Author:	Levi, Michael\|Prayogi, Gintang\|Sastranagara, Farid\|Sudianto, Edi\|Widjajahakim, Grace\|Gani, Winiarti\|Mahanadi, Albert\|Agnes, Jocelyn\|Khairunisa, Bela Haifa\|Utomo, Ahmad R
PMID:	28044264

3201.
Journal:	J Cell Physiol. 2018 Mar;233(3):2058-2066.
Title:	Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer.
Author:	Bahrami, Afsane\|Hassanian, Seyed Mahdi\|ShahidSales, Soodabeh\|Farjami, Zahra\|Hasanzadeh, Malihe\|Anvari, Kazem\|Aledavood, Amir\|Maftouh, Mina\|Ferns, Gordon A\|Khazaei, Majid\|Avan, Amir
PMID:	28262927

3202.
Journal:	J Clin Gastroenterol. 2018 May/Jun;52(5):431-436.
Title:	Clinical Predictors for KRAS Codon 13 Mutations in Patients With Colorectal Cancer.
Author:	Kwak, Min S\|Cha, Jae M\|Cho, Young H\|Kim, Sang H\|Yoon, Jin Y\|Jeon, Jung W\|Shin, Hyun P\|Joo, Kwang R\|Lee, Joung I
PMID:	28277374

3203.
Journal:	Asia Pac J Clin Oncol. 2018 Apr;14(2):e167-e174.
Title:	How accurate are medical oncologists' impressions of management of metastatic colorectal cancer in Australia?
Author:	Au, Lewis\|Turner, Natalie\|Wong, Hui-Li\|Field, Kathryn\|Lee, Belinda\|Boadle, David\|Cooray, Prasad\|Karikios, Deme\|Kosmider, Suzanne\|Lipton, Lara\|Nott, Louise\|Parente, Phillip\|Tie, Jeanne\|Tran, Ben\|Wong, Rachel\|Yip, Desmond\|Shapiro, Jeremy\|Gibbs, Peter
PMID:	28299879

3204.
Journal:	Curr Cancer Drug Targets. 2018;18(3):278-286.
Title:	Effects of PHA-665752 and Cetuximab Combination Treatment on In Vitro and Murine Xenograft Growth of Human Colorectal Cancer Cells with KRAS or BRAF Mutations.
Author:	Jia, Yi-Tao\|Yang, Dong-Hai\|Zhao, Zhaolong\|Bi, Xiao-Hui\|Han, Wei-Hua\|Feng, Bo\|Zhi, Jie\|Gu, Bin\|Duan, Zhihui\|Wu, Jian-Hua\|Ju, Ying-Chao\|Wang, Ming-Xia\|Li, Zhong-Xin
PMID:	28359236

3205.
Journal:	J Gastrointest Cancer. 2018 Sep;49(3):283-287.
Title:	Left Versus Right: Does Location Matter for Refractory Metastatic Colorectal Cancer Patients in Phase 1 Clinical Trials?
Author:	Arora, Sukeshi Patel\|Ketchum, Norma S\|Michalek, Joel\|Gelfond, Jonathon\|Mahalingam, Devalingam
PMID:	28432610

3206.
Journal:	Histopathology. 2018 Feb;72(3):391-404.
Title:	Intratumoral stromal morphometry predicts disease recurrence but not response to 5-fluorouracil-results from the QUASAR trial of colorectal cancer.
Author:	Hutchins, Gordon G A\|Treanor, Darren\|Wright, Alexander\|Handley, Kelly\|Magill, Laura\|Tinkler-Hundal, Emma\|Southward, Katie\|Seymour, Matthew\|Kerr, David\|Gray, Richard\|Quirke, Philip
PMID:	28746977

3207.
Journal:	J Gastroenterol. 2018 Apr;53(4):517-524.
Title:	Fusobacterium nucleatum as a prognostic marker of colorectal cancer in a Japanese population.
Author:	Yamaoka, Yuko\|Suehiro, Yutaka\|Hashimoto, Shinichi\|Hoshida, Tomomi\|Fujimoto, Michiyo\|Watanabe, Michiya\|Imanaga, Daiki\|Sakai, Kouhei\|Matsumoto, Toshihiko\|Nishioka, Mitsuaki\|Takami, Taro\|Suzuki, Nobuaki\|Hazama, Shoichi\|Nagano, Hiroaki\|Sakaida, Isao\|Yamasaki,
PMID:	28823057

3208.
Journal:	Am J Surg Pathol. 2018 Feb;42(2):172-182.
Title:	Clinicopathologic and Molecular Characteristics of Synchronous Colorectal Carcinoma With Mismatch Repair Deficiency.
Author:	Nakano, Kayoko\|Yamamoto, Hidetaka\|Fujiwara, Minako\|Koga, Yutaka\|Tsuruta, Shinichi\|Ihara, Eikichi\|Oki, Eiji\|Nakamura, Masafumi\|Ogawa, Yoshihiro\|Oda, Yoshinao
PMID:	28877066

3209.
Journal:	Histopathology. 2018 Feb;72(3):423-432.
Title:	Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones.
Author:	Bae, Jeong Mo\|Kim, Jung Ho\|Park, Jeong Hwan\|Park, Hye Eun\|Cho, Nam-Yun\|Kang, Gyeong Hoon
PMID:	28914964

3210.
Journal:	Int J Cancer. 2018 Jan 15;142(2):238-250.
Title:	Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype.
Author:	Jayasekara, Harindra\|English, Dallas R\|Haydon, Andrew\|Hodge, Allison M\|Lynch, Brigid M\|Rosty, Christophe\|Williamson, Elizabeth J\|Clendenning, Mark\|Southey, Melissa C\|Jenkins, Mark A\|Room, Robin\|Hopper, John L\|Milne, Roger L\|Buchanan, Daniel D\|Giles, Graha
PMID:	28921583

3211.
Journal:	Mol Cell Biochem. 2018 May;442(1-2):39-45.
Title:	A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.
Author:	Okamoto, Haruna\|Matsukawa, Taiji\|Doi, Satoshi\|Tsunoda, Toshiyuki\|Sawata, Yuuga\|Naemura, Madoka\|Ohnuki, Koichiro\|Shirasawa, Senji\|Kotake, Yojiro
PMID:	28936721

3212.
Journal:	Ann Oncol. 2018 Jan 1;29(1):112-118.
Title:	RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
Author:	Normanno, N\|Esposito Abate, R\|Lambiase, M\|Forgione, L\|Cardone, C\|Iannaccone, A\|Sacco, A\|Rachiglio, A M\|Martinelli, E\|Rizzi, D\|Pisconti, S\|Biglietto, M\|Bordonaro, R\|Troiani, T\|Latiano, T P\|Giuliani, F\|Leo, S\|Rinaldi, A\|Maiello, E\|Ciardiello, F
PMID:	28950295

3213.
Journal:	Mod Pathol. 2018 Feb;31(2):343-349.
Title:	Optimal detection of clinically relevant mutations in colorectal carcinoma: sample pooling overcomes intra-tumoral heterogeneity.
Author:	Nelson, Andrew C\|Boone, Jamie\|Cartwright, David\|Thyagarajan, Bharat\|Kincaid, Robyn\|Lambert, Aaron P\|Karnuth, Kylene\|Henzler, Christine\|Yohe, Sophia
PMID:	29027537

3214.
Journal:	Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):365-375.
Title:	FDG PET/CT radiomics for predicting the outcome of locally advanced rectal cancer.
Author:	Lovinfosse, Pierre\|Polus, Marc\|Van Daele, Daniel\|Martinive, Philippe\|Daenen, Frederic\|Hatt, Mathieu\|Visvikis, Dimitris\|Koopmansch, Benjamin\|Lambert, Frederic\|Coimbra, Carla\|Seidel, Laurence\|Albert, Adelin\|Delvenne, Philippe\|Hustinx, Roland
PMID:	29046927

3215.
Journal:	Mod Pathol. 2018 Mar;31(3):517-526.
Title:	Association between clinicopathological characteristics and RAS mutation in colorectal cancer.
Author:	Rimbert, Johan\|Tachon, Gaelle\|Junca, Audelaure\|Villalva, Claire\|Karayan-Tapon, Lucie\|Tougeron, David
PMID:	29052598

3216.
Journal:	Clin Cancer Res. 2018 Jan 1;24(1):224-233.
Title:	KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.
Author:	Lal, Neeraj\|White, Brian S\|Goussous, Ghaleb\|Pickles, Oliver\|Mason, Mike J\|Beggs, Andrew D\|Taniere, Philippe\|Willcox, Benjamin E\|Guinney, Justin\|Middleton, Gary W
PMID:	29061646

3217.
Journal:	Mol Carcinog. 2018 Feb;57(2):284-294.
Title:	BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.
Author:	Wang, Chun Yan\|Guo, Su Tang\|Croft, Amanda\|Yan, Xu Guang\|Jin, Lei\|Zhang, Xu Dong\|Jiang, Chen Chen
PMID:	29068469

3218.
Journal:	JAMA Oncol. 2018 Apr 1;4(4):564-568.
Title:	Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.
Author:	Seligmann, Jenny F\|Hatch, Ace J\|Richman, Susan D\|Elliott, Faye\|Jacobs, Bart\|Brown, Sarah\|Hurwitz, Herbert\|Barrett, Jennifer H\|Quirke, Philip\|Nixon, Andrew B\|Seymour, Matthew T
PMID:	29075780

3219.
Journal:	Hum Pathol. 2018 Jan;71:145-156.
Title:	Clinical and biological significance of miR-193a-3p targeted KRAS in colorectal cancer pathogenesis.
Author:	Mamoori, Afraa\|Wahab, Riajul\|Islam, Farhadul\|Lee, Katherine\|Vider, Jelena\|Lu, Cu-Tai\|Gopalan, Vinod\|Lam, Alfred King-Yin
PMID:	29104111

3220.
Journal:	Cancer Prev Res (Phila). 2018 Jan;11(1):16-26.
Title:	Does Mutated K-RAS Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?
Author:	Rice, Photini F S\|Ehrichs, Kevin G\|Jones, Mykella S\|Chen, Hwudarw\|Hsu, Chiu-Hsieh\|Abril, Edward R\|Nagle, Raymond B\|Besselsen, David G\|Barton, Jennifer K\|Ignatenko, Natalia A
PMID:	29118162

3221.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):73-79.
Title:	Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.
Author:	Chiu, Joanne W\|Krzyzanowska, Monika K\|Serra, Stefano\|Knox, Jennifer J\|Dhani, Neesha C\|Mackay, Helen\|Hedley, David\|Moore, Malcolm\|Liu, Geoffrey\|Burkes, Ronald L\|Brezden-Masley, Christine\|Roehrl, Michael H\|Craddock, Kenneth J\|Tsao, Ming-Sound\|Zhang, Tong\|Yu
PMID:	29128266

3222.
Journal:	Mol Oncol. 2018 Jan;12(1):132-147.
Title:	Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures.
Author:	Arnadottir, Sigrid S\|Jeppesen, Maria\|Lamy, Philippe\|Bramsen, Jesper B\|Nordentoft, Iver\|Knudsen, Michael\|Vang, Soren\|Madsen, Mogens R\|Thastrup, Ole\|Thastrup, Jacob\|L Andersen, Claus
PMID:	29130628

3223.
Journal:	Clin Cancer Res. 2018 Mar 1;24(5):1062-1072.
Title:	Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes.
Author:	Loree, Jonathan M\|Pereira, Allan A L\|Lam, Michael\|Willauer, Alexandra N\|Raghav, Kanwal\|Dasari, Arvind\|Morris, Van K\|Advani, Shailesh\|Menter, David G\|Eng, Cathy\|Shaw, Kenna\|Broaddus, Russell\|Routbort, Mark J\|Liu, Yusha\|Morris, Jeffrey S\|Luthra, Rajyalakshm
PMID:	29180604

3224.
Journal:	Pharmacol Rev. 2018 Jan;70(1):1-11.
Title:	RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.
Author:	Yan, Chao\|Theodorescu, Dan
PMID:	29196555

3225.
Journal:	Oncol Rep. 2018 Feb;39(2):619-626.
Title:	Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression.
Author:	Chen, Meiya\|Lin, Mengjie\|Wang, Xiaozhong
PMID:	29207158

3226.
Journal:	Mol Cancer Res. 2018 Mar;16(3):486-495.
Title:	Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.
Author:	Drew, David A\|Mo, Allen\|Grady, James J\|Stevens, Richard G\|Levine, Joel B\|Brenner, Bruce M\|Anderson, Joseph C\|Forouhar, Faripour\|O'Brien, Michael J\|Devers, Thomas J\|Rosenberg, Daniel W
PMID:	29222172

3227.
Journal:	Mol Carcinog. 2018 Mar;57(3):451-461.
Title:	Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers.
Author:	Sugai, Tamotsu\|Takahashi, Yayoi\|Eizuka, Makoto\|Sugimoto, Ryo\|Fujita, Yasuko\|Habano, Wataru\|Otsuka, Kouki\|Sasaki, Akira\|Yamamoto, Eiichiro\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	29230882

3228.
Journal:	Clin Colorectal Cancer. 2018 Mar;17(1):e121-e125.
Title:	Cetuximab Combined With Induction Oxaliplatin and Capecitabine, Followed by Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer: SWOG 0713.
Author:	Leichman, Cynthia Gail\|McDonough, Shannon L\|Smalley, Stephen R\|Billingsley, Kevin G\|Lenz, Heinz-Josef\|Beldner, Matthew A\|Hezel, Aram F\|Velasco, Mario R\|Guthrie, Katherine A\|Blanke, Charles D\|Hochster, Howard S
PMID:	29233486

3229.
Journal:	Am J Surg Pathol. 2018 Mar;42(3):351-358.
Title:	Site-specific Differences in Colonic Adenocarcinoma: KRAS Mutations and High Tumor Budding Are More Frequent in Cecal Adenocarcinoma.
Author:	Landau, Michael A\|Zhu, Benjamin\|Akwuole, Frances N\|Pai, Reetesh K
PMID:	29240583

3230.
Journal:	Eur J Cancer. 2018 Jan;89:82-89.
Title:	Neoadjuvant radiotherapy combined with capecitabine and sorafenib in patients with advanced KRAS-mutated rectal cancer: A phase I/II trial (SAKK 41/08).
Author:	von Moos, Roger\|Koeberle, Dieter\|Schacher, Sabina\|Hayoz, Stefanie\|Winterhalder, Ralph C\|Roth, Arnaud\|Bodoky, Gyorgy\|Samaras, Panagiotis\|Berger, Martin D\|Rauch, Daniel\|Saletti, Piercarlo\|Plasswilm, Ludwig\|Zwahlen, Daniel\|Meier, Urs R\|Yan, Pu\|Izzo, Paola\|Kl
PMID:	29241084

3231.
Journal:	Lancet Gastroenterol Hepatol. 2018 Mar;3(3):162-171.
Title:	Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2-3 randomised trial.
Author:	Adams, Richard\|Brown, Ewan\|Brown, Louise\|Butler, Rachel\|Falk, Stephen\|Fisher, David\|Kaplan, Richard\|Quirke, Phil\|Richman, Susan\|Samuel, Leslie\|Seligmann, Jenny\|Seymour, Matt\|Shiu, Kai Keen\|Wasan, Harpreet\|Wilson, Richard\|Maughan, Tim
PMID:	29254887

3232.
Journal:	J Natl Cancer Inst. 2018 Jun 1;110(6):638-648.
Title:	Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project.
Author:	Sjoquist, Katrin M\|Renfro, Lindsay A\|Simes, R John\|Tebbutt, Niall C\|Clarke, Stephen\|Seymour, Matthew T\|Adams, Richard\|Maughan, Timothy S\|Saltz, Leonard\|Goldberg, Richard M\|Schmoll, Hans-Joachim\|Van Cutsem, Eric\|Douillard, Jean-Yves\|Hoff, Paulo M\|Hecht, Jo
PMID:	29267900

3233.
Journal:	Cancer Res. 2018 Mar 1;78(5):1334-1346.
Title:	Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer.
Author:	Sakai, Eri\|Nakayama, Mizuho\|Oshima, Hiroko\|Kouyama, Yuta\|Niida, Atsushi\|Fujii, Satoshi\|Ochiai, Atsushi\|Nakayama, Keiichi I\|Mimori, Koshi\|Suzuki, Yutaka\|Hong, Chang Pyo\|Ock, Chan-Young\|Kim, Seong-Jin\|Oshima, Masanobu
PMID:	29282223

3234.
Journal:	Pharmacogenomics J. 2018 Jul;18(4):556-564.
Title:	Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon cancer.
Author:	Riera, Pau\|Virgili, Anna C\|Salazar, Juliana\|Sebio, Ana\|Tobena, Maria\|Sullivan, Ivana\|Paez, David
PMID:	29282362

3235.
Journal:	Genome Med. 2018 Jan 4;10(1):2.
Title:	Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
Author:	Kundu, Snehangshu\|Ali, Muhammad Akhtar\|Handin, Niklas\|Padhan, Narendra\|Larsson, Jimmy\|Karoutsou, Maria\|Ban, Kenneth\|Wisniewski, Jacek R\|Artursson, Per\|He, Liqun\|Hellstrom, Mats\|Sjoblom, Tobias
PMID:	29301589

3236.
Journal:	Sensors (Basel). 2018 Jan 5;18(1). pii: s18010131.
Title:	Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.
Author:	Guarnaccia, Maria\|Iemmolo, Rosario\|San Biagio, Floriana\|Alessi, Enrico\|Cavallaro, Sebastiano
PMID:	29304017

3237.
Journal:	Adv Clin Chem. 2018;83:53-72.
Title:	Locked Nucleic Acid Technology for Highly Sensitive Detection of Somatic Mutations in Cancer.
Author:	Ishige, Takayuki\|Itoga, Sakae\|Matsushita, Kazuyuki
PMID:	29304903

3238.
Journal:	Clin Gastroenterol Hepatol. 2018 Jan 3. pii: S1542-3565(17)31536-7.
Title:	Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review.
Author:	Alwers, Elizabeth\|Jia, Min\|Kloor, Matthias\|Blaker, Hendrik\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	29306042

3239.
Journal:	Scand J Gastroenterol. 2018 Mar;53(3):273-278.
Title:	Multi-target stool DNA test in the surveillance of inflammatory bowel disease: a cross-sectional cohort study.
Author:	Klepp, Pasquale\|Kisiel, John B\|Smastuen, Milada Cvancarova\|Roseth, Arne\|Andersen, Solveig N\|Vatn, Morten H\|Ahlquist, David A\|Moum, Bjorn A\|Brackmann, Stephan
PMID:	29313389

3240.
Journal:	Cancer Cell. 2018 Jan 8;33(1):125-136.e3.
Title:	Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Author:	Yaeger, Rona\|Chatila, Walid K\|Lipsyc, Marla D\|Hechtman, Jaclyn F\|Cercek, Andrea\|Sanchez-Vega, Francisco\|Jayakumaran, Gowtham\|Middha, Sumit\|Zehir, Ahmet\|Donoghue, Mark T A\|You, Daoqi\|Viale, Agnes\|Kemeny, Nancy\|Segal, Neil H\|Stadler, Zsofia K\|Varghese, Anna
PMID:	29316426

3241.
Journal:	Cancer Metastasis Rev. 2018 Mar;37(1):173-187.
Title:	Mutations of key driver genes in colorectal cancer progression and metastasis.
Author:	Huang, Dongdong\|Sun, Wenjie\|Zhou, Yuwei\|Li, Peiwei\|Chen, Fang\|Chen, Hanwen\|Xia, Dajing\|Xu, Enping\|Lai, Maode\|Wu, Yihua\|Zhang, Honghe
PMID:	29322354

3242.
Journal:	Mod Pathol. 2018 May;31(5):829-839.
Title:	Appendiceal goblet cell carcinoids and adenocarcinomas ex-goblet cell carcinoid are genetically distinct from primary colorectal-type adenocarcinoma of the appendix.
Author:	Jesinghaus, Moritz\|Konukiewitz, Bjorn\|Foersch, Sebastian\|Stenzinger, Albrecht\|Steiger, Katja\|Muckenhuber, Alexander\|Gross, Claudia\|Mollenhauer, Martin\|Roth, Wilfried\|Detlefsen, Sonke\|Weichert, Wilko\|Kloppel, Gunter\|Pfarr, Nicole\|Schlitter, Anna Melissa
PMID:	29327707

3243.
Journal:	Virchows Arch. 2018 May;472(5):717-725.
Title:	RAS testing for colorectal cancer patients is reliable in European laboratories that pass external quality assessment.
Author:	Tack, V\|Ligtenberg, M J L\|Siebers, A G\|Rombout, P D M\|Dabir, P D\|Weren, R D A\|van Krieken, J H J M\|Dequeker, E M C
PMID:	29333594

3244.
Journal:	Eur Radiol. 2018 May;28(5):2058-2067.
Title:	Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer?
Author:	Yang, Lei\|Dong, Di\|Fang, Mengjie\|Zhu, Yongbei\|Zang, Yali\|Liu, Zhenyu\|Zhang, Hongmei\|Ying, Jianming\|Zhao, Xinming\|Tian, Jie
PMID:	29335867

3245.
Journal:	Exp Mol Pathol. 2018 Feb;104(1):98-107.
Title:	MiR-142-5p act as an oncogenic microRNA in colorectal cancer: Clinicopathological and functional insights.
Author:	Islam, Farhadul\|Gopalan, Vinod\|Vider, Jelena\|Lu, Cu-Tai\|Lam, Alfred K-Y
PMID:	29337244

3246.
Journal:	Cancer. 2018 Apr 1;124(7):1358-1373.
Title:	Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.
Author:	Ross, Jeffrey S\|Fakih, Marwan\|Ali, Siraj M\|Elvin, Julia A\|Schrock, Alexa B\|Suh, James\|Vergilio, Jo-Anne\|Ramkissoon, Shakti\|Severson, Eric\|Daniel, Sugganth\|Fabrizio, David\|Frampton, Garrett\|Sun, James\|Miller, Vincent A\|Stephens, Philip J\|Gay, Laurie M
PMID:	29338072

3247.
Journal:	Anticancer Res. 2018 Feb;38(2):677-683.
Title:	MicroRNA Expression in KRAS- and BRAF-mutated Colorectal Cancers.
Author:	Lundberg, Ida V\|Wikberg, Maria L\|Ljuslinder, Ingrid\|Li, Xingru\|Myte, Robin\|Zingmark, Carl\|Lofgren-Burstrom, Anna\|Edin, Sofia\|Palmqvist, Richard
PMID:	29374690

3248.
Journal:	Sci Rep. 2018 Jan 29;8(1):1791.
Title:	A Low-Cost Palmtop High-Speed Capillary Electrophoresis Bioanalyzer with Laser Induced Fluorescence Detection.
Author:	Pan, Jian-Zhang\|Fang, Pan\|Fang, Xiao-Xia\|Hu, Ting-Ting\|Fang, Jin\|Fang, Qun
PMID:	29379053

3249.
Journal:	J Clin Lab Anal. 2018 Jun;32(5):e22391.
Title:	A novel cell line generated using the CRISPR/Cas9 technology as universal quality control material for KRAS G12V mutation testing.
Author:	Jia, Shiyu\|Zhang, Rui\|Lin, Guigao\|Peng, Rongxue\|Gao, Peng\|Han, Yanxi\|Fu, Yu\|Ding, Jiansheng\|Wu, Qisheng\|Zhang, Kuo\|Xie, Jiehong\|Li, Jinming
PMID:	29380513

3250.
Journal:	Acta Oncol. 2018 Aug;57(8):1057-1062.
Title:	Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.
Author:	Christensen, Troels Dreier\|Palshof, Jesper Andreas\|Larsen, Finn Ole\|Poulsen, Tim Svenstrup\|Hogdall, Estrid\|Pfeiffer, Per\|Jensen, Benny Vittrup\|Yilmaz, Mette Karen\|Nielsen, Dorte
PMID:	29380640

3251.
Journal:	Gut. 2018 Jan 30. pii: gutjnl-2017-315664.
Title:	Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes.
Author:	Williams, David S\|Mouradov, Dmitri\|Jorissen, Robert N\|Newman, Marsali R\|Amini, Elham\|Nickless, David K\|Teague, Julie A\|Fang, Catherine G\|Palmieri, Michelle\|Parsons, Marie J\|Sakthianandeswaren, Anuratha\|Li, Shan\|Ward, Robyn L\|Hawkins, Nicholas J\|Faragher,
PMID:	29382774

3252.
Journal:	Cost Eff Resour Alloc. 2018 Jan 22;16:2.
Title:	Personalized medicine in colorectal cancer diagnosis and treatment: a systematic review of health economic evaluations.
Author:	Guglielmo, Annamaria\|Staropoli, Nicoletta\|Giancotti, Monica\|Mauro, Marianna
PMID:	29386984

3253.
Journal:	J Gastrointest Cancer. 2018 Feb 1. pii: 10.1007/s12029-018-0062-y.
Title:	Clinical Impact of PI3K/BRAF Mutations in RAS Wild Metastatic Colorectal Cancer: Meta-analysis Results.
Author:	Mohamed, Amr\|Twardy, Brandon\|AbdAllah, Nadine\|Akhras, Alaa\|Ismail, Hibah\|Zordok, Magdi\|Schrapp, Kelly\|Attumi, Taraq\|Tesfaye, Anteneh\|El-Rayes, Bassel
PMID:	29388061

3254.
Journal:	Lancet Gastroenterol Hepatol. 2018 Apr;3(4):263-270.
Title:	Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial.
Author:	Jonker, Derek J\|Nott, Louise\|Yoshino, Takayuki\|Gill, Sharlene\|Shapiro, Jeremy\|Ohtsu, Atsushi\|Zalcberg, John\|Vickers, Michael M\|Wei, Alice C\|Gao, Yuan\|Tebbutt, Niall C\|Markman, Ben\|Price, Timothy\|Esaki, Taito\|Koski, Sheryl\|Hitron, Matthew\|Li, Wei\|Li, Youzh
PMID:	29397354

3255.
Journal:	J Clin Oncol. 2018 May 1;36(13):1291-1299.
Title:	Phosphatidylinositol 3-Kinase alpha-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.
Author:	Juric, Dejan\|Rodon, Jordi\|Tabernero, Josep\|Janku, Filip\|Burris, Howard A\|Schellens, Jan H M\|Middleton, Mark R\|Berlin, Jordan\|Schuler, Martin\|Gil-Martin, Marta\|Rugo, Hope S\|Seggewiss-Bernhardt, Ruth\|Huang, Alan\|Bootle, Douglas\|Demanse, David\|Blumenstein, L
PMID:	29401002

3256.
Journal:	BMC Cancer. 2018 Feb 5;18(1):136.
Title:	Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.
Author:	Klauck, Peter J\|Bagby, Stacey M\|Capasso, Anna\|Bradshaw-Pierce, Erica L\|Selby, Heather M\|Spreafico, Anna\|Tentler, John J\|Tan, Aik Choon\|Kim, Jihye\|Arcaroli, John J\|Purkey, Alicia\|Messersmith, Wells A\|Kuida, Keisuke\|Eckhardt, S Gail\|Pitts, Todd M
PMID:	29402316

3257.
Journal:	Onco Targets Ther. 2018 Jan 22;11:465-471.
Title:	Subsequent anti-VEGF therapy after first-line anti-EGFR therapy improved overall survival of patients with metastatic colorectal cancer.
Author:	Qiu, Tianzhu\|Chen, Wensen\|Li, Ping\|Sun, Jing\|Gu, Yanhong\|Chen, Xiaofeng
PMID:	29403291

3258.
Journal:	Clin Genet. 2018 May;93(5):1015-1021.
Title:	Spectrum of APC and MUTYH germ-line mutations in Russian patients with colorectal malignancies.
Author:	Yanus, G A\|Akhapkina, T A\|Ivantsov, A O\|Preobrazhenskaya, E V\|Aleksakhina, S N\|Bizin, I V\|Sokolenko, A P\|Mitiushkina, N V\|Kuligina, E Sh\|Suspitsin, E N\|Venina, A R\|Holmatov, M M\|Zaitseva, O A\|Yatsuk, O S\|Pashkov, D V\|Belyaev, A M\|Togo, A V\|Imyanitov, E N\|
PMID:	29406563

3259.
Journal:	Hum Pathol. 2018 Apr;74:178-182.
Title:	KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
Author:	Tessitore, Alessandra\|Bruera, Gemma\|Mastroiaco, Valentina\|Cannita, Katia\|Cortellini, Alessio\|Cocciolone, Valentina\|Dal Mas, Antonella\|Calvisi, Giuseppe\|Zazzeroni, Francesca\|Ficorella, Corrado\|Ricevuto, Enrico\|Alesse, Edoardo
PMID:	29409955

3260.
Journal:	Pathobiology. 2018;85(1-2):72-84.
Title:	Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?
Author:	Sagaert, Xavier\|Vanstapel, Arno\|Verbeek, Sanne
PMID:	29414818

3261.
Journal:	Oncotarget. 2017 Dec 12;9(1):969-981.
Title:	Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling.
Author:	Fujita, Masashi\|Matsubara, Nagahide\|Matsuda, Ikuo\|Maejima, Kazuhiro\|Oosawa, Ayako\|Yamano, Tomoki\|Fujimoto, Akihiro\|Furuta, Mayuko\|Nakano, Kaoru\|Oku-Sasaki, Aya\|Tanaka, Hiroko\|Shiraishi, Yuichi\|Mateos, Raul Nicolas\|Nakai, Kenta\|Miyano, Satoru\|Tomita, Naohi
PMID:	29416670

3262.
Journal:	PeerJ. 2018 Feb 5;6:e4341.
Title:	Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China.
Author:	Zhang, Xiangyan\|Ran, Wenwen\|Wu, Jie\|Li, Hong\|Liu, Huamin\|Wang, Lili\|Xiao, Yujing\|Wang, Xiaonan\|Li, Yujun\|Xing, Xiaoming
PMID:	29423347

3263.
Journal:	Int J Cancer. 2018 Jul 1;143(1):139-150.
Title:	Three molecular pathways model colorectal carcinogenesis in Lynch syndrome.
Author:	Ahadova, Aysel\|Gallon, Richard\|Gebert, Johannes\|Ballhausen, Alexej\|Endris, Volker\|Kirchner, Martina\|Stenzinger, Albrecht\|Burn, John\|von Knebel Doeberitz, Magnus\|Blaker, Hendrik\|Kloor, Matthias
PMID:	29424427

3264.
Journal:	Cancer Discov. 2018 Apr;8(4):428-443.
Title:	Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF(V600E)-Mutant Colorectal Cancer.
Author:	Corcoran, Ryan B\|Andre, Thierry\|Atreya, Chloe E\|Schellens, Jan H M\|Yoshino, Takayuki\|Bendell, Johanna C\|Hollebecque, Antoine\|McRee, Autumn J\|Siena, Salvatore\|Middleton, Gary\|Muro, Kei\|Gordon, Michael S\|Tabernero, Josep\|Yaeger, Rona\|O'Dwyer, Peter J\|Humble
PMID:	29431699

3265.
Journal:	Oncol Lett. 2018 Mar;15(3):3161-3166.
Title:	Mutations in KRAS codon 12 predict poor survival in Chinese patients with metastatic colorectal cancer.
Author:	Bai, Bingjun\|Shan, Lina\|Xie, Binbin\|Huang, Xuefeng\|Mao, Weifang\|Wang, Xiaowei\|Wang, Da\|Zhu, Hongbo
PMID:	29435051

3266.
Journal:	Oncotarget. 2017 Dec 20;9(4):4707-4721.
Title:	Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.
Author:	Aoki, Hironori\|Yamamoto, Eiichiro\|Takasawa, Akira\|Niinuma, Takeshi\|Yamano, Hiro-O\|Harada, Taku\|Matsushita, Hiro-O\|Yoshikawa, Kenjiro\|Takagi, Ryo\|Harada, Eiji\|Tanaka, Yoshihito\|Yoshida, Yuko\|Aoyama, Tomoyuki\|Eizuka, Makoto\|Yorozu, Akira\|Kitajima, Hiroshi\|K
PMID:	29435136

3267.
Journal:	Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: mcs.a002535.
Title:	Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases.
Author:	Owen, Daniel R\|Wong, Hui-Li\|Bonakdar, Melika\|Jones, Martin\|Hughes, Christopher S\|Morin, Gregg B\|Jones, Steven J M\|Renouf, Daniel J\|Lim, Howard\|Laskin, Janessa\|Marra, Marco\|Yip, Stephen\|Schaeffer, David F
PMID:	29438965

3268.
Journal:	Gut. 2018 Mar;67(3):447-455.
Title:	Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment.
Author:	Rigter, Lisanne S\|Snaebjornsson, Petur\|Rosenberg, Efraim H\|Atmodimedjo, Peggy N\|Aleman, Berthe M\|Ten Hoeve, Jelle\|Geurts-Giele, Willemina R\|van Ravesteyn, Thomas W\|Hoeksel, Johan\|Meijer, Gerrit A\|Te Riele, Hein\|van Leeuwen, Flora E\|Dinjens, Winand N\|van L
PMID:	29439113

3269.
Journal:	Adv Biol Regul. 2018 May;68:46-54.
Title:	Interaction of the Wnt/beta-catenin and RAS-ERK pathways involving co-stabilization of both beta-catenin and RAS plays important roles in the colorectal tumorigenesis.
Author:	Lee, Sang-Kyu\|Hwang, Jeong-Ha\|Choi, Kang-Yell
PMID:	29449169

3270.
Journal:	Cell Death Dis. 2018 Feb 15;9(3):271.
Title:	PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.
Author:	Huang, Lanlan\|Wen, Chuangyu\|Yang, Xiangling\|Lou, Qiong\|Wang, Xiaoyan\|Che, Jia\|Chen, Junxiong\|Yang, Zihuan\|Wu, Xiaojian\|Huang, Meijin\|Lan, Ping\|Wang, Lei\|Iwamoto, Aikichi\|Wang, Jianping\|Liu, Huanliang
PMID:	29449544

3271.
Journal:	Eur Radiol. 2018 Jul;28(7):3059-3065.
Title:	Could IVIM and ADC help in predicting the KRAS status in patients with rectal cancer?
Author:	Xu, Yanyan\|Xu, Qiaoyu\|Sun, Hongliang\|Liu, Tongxi\|Shi, Kaining\|Wang, Wu
PMID:	29450716

3272.
Journal:	Cancer Lett. 2018 May 1;421:161-169.
Title:	Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author:	Lin, Yun-Kai\|Fang, Zheng\|Jiang, Tian-Yi\|Wan, Zheng-Hua\|Pan, Yu-Fei\|Ma, Yun-Han\|Shi, Yuan-Yuan\|Tan, Ye-Xiong\|Dong, Li-Wei\|Zhang, Yong-Jie\|Wang, Hong-Yang
PMID:	29452147

3273.
Journal:	Clin Drug Investig. 2018 Jun;38(6):553-562.
Title:	First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author:	Moiseyenko, Vladimir M\|Moiseyenko, Fedor V\|Yanus, Grigoriy A\|Kuligina, Ekatherina Sh\|Sokolenko, Anna P\|Bizin, Ilya V\|Kudriavtsev, Alexey A\|Aleksakhina, Svetlana N\|Volkov, Nikita M\|Chubenko, Vyacheslav A\|Kozyreva, Kseniya S\|Kramchaninov, Mikhail M\|Zhuravle
PMID:	29470838

3274.
Journal:	Cell Biol Toxicol. 2018 Feb 24. pii: 10.1007/s10565-018-9423-3.
Title:	Colorectal cancer spheroid biobanks: multi-level approaches to drug sensitivity studies.
Author:	De Angelis, Maria Laura\|Bruselles, Alessandro\|Francescangeli, Federica\|Pucilli, Flavia\|Vitale, Sara\|Zeuner, Ann\|Tartaglia, Marco\|Baiocchi, Marta
PMID:	29478126

3275.
Journal:	Int J Biol Sci. 2018 Jan 12;14(2):111-123.
Title:	The role of TGF-beta/SMAD4 signaling in cancer.
Author:	Zhao, Ming\|Mishra, Lopa\|Deng, Chu-Xia
PMID:	29483830

3276.
Journal:	Oncotarget. 2017 Nov 16;9(7):7739-7748.
Title:	Review on comparative efficacy of bevacizumab, panitumumab and cetuximab antibody therapy with combination of FOLFOX-4 in KRAS-mutated colorectal cancer patients.
Author:	Pathak, Surajit\|S, Sushmitha\|Banerjee, Antara\|Marotta, Francesco\|Gopinath, Madhumala\|Murugesan, Ramachandran\|Zhang, Hong\|B, Bhavani\|Girigoswami, Agnishwar\|Sollano, Jose\|Sun, Xiao-Feng
PMID:	29484148

3277.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):235-242.
Title:	Systemic Therapy for Colon Cancer.
Author:	Wu, Christina
PMID:	29496087

3278.
Journal:	Surg Oncol Clin N Am. 2018 Apr;27(2):349-365.
Title:	Clinical Trials and Progress in Metastatic Colon Cancer.
Author:	Mody, Kabir\|Bekaii-Saab, Tanios
PMID:	29496094

3279.
Journal:	Pathol Res Pract. 2018 Mar;214(3):350-355.
Title:	Expression of miR-200c and its clinicopathological significance in patients with colorectal cancer.
Author:	Roh, Mee Sook\|Lee, Hyoun Wook\|Jung, Sang Bong\|Kim, Kyungeun\|Lee, Eun Hee\|Park, Moon-Il\|Lee, Jae Seok\|Kim, Mee-Seon
PMID:	29496312

3280.
Journal:	Cancer Sci. 2018 May;109(5):1455-1467.
Title:	Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
Author:	Akao, Yukihiro\|Kumazaki, Minami\|Shinohara, Haruka\|Sugito, Nobuhiko\|Kuranaga, Yuki\|Tsujino, Takuya\|Yoshikawa, Yuki\|Kitade, Yukio
PMID:	29498789

3281.
Journal:	Oncotarget. 2018 Jan 10;9(10):9088-9099.
Title:	Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells.
Author:	Bennett Saidu, Nathaniel Edward\|Bretagne, Marie\|Mansuet, Audrey Lupo\|Just, Pierre-Alexandre\|Leroy, Karen\|Cerles, Olivier\|Chouzenoux, Sandrine\|Nicco, Carole\|Damotte, Diane\|Alifano, Marco\|Borghese, Bruno\|Goldwasser, Francois\|Batteux, Frederic\|Alexandre, Jer
PMID:	29507676

3282.
Journal:	Oncotarget. 2018 Jan 3;9(10):9100-9113.
Title:	New localization and function of calpain-2 in nucleoli of colorectal cancer cells in ribosomal biogenesis: effect of KRAS status.
Author:	Telechea-Fernandez, Marcelino\|Rodriguez-Fernandez, Lucia\|Garcia, Concha\|Zaragoza, Rosa\|Vina, Juan\|Cervantes, Andres\|Garcia-Trevijano, Elena R
PMID:	29507677

3283.
Journal:	Cancer Chemother Pharmacol. 2018 May;81(5):829-838.
Title:	A phase II trial to evaluate the efficacy of panitumumab combined with fluorouracil-based chemotherapy for metastatic colorectal cancer: the PF trial.
Author:	Munemoto, Yoshinori\|Kanda, Mitsuro\|Oba, Koji\|Kim, Ho Min\|Takemoto, Hiroyoshi\|Denda, Tadamichi\|Nagata, Naoki\|Takano, Nao\|Fukunaga, Mutsumi\|Kataoka, Masato\|Tokunaga, Yukihiko\|Sakamoto, Junichi\|Mishima, Hideyuki
PMID:	29508026

3284.
Journal:	United European Gastroenterol J. 2018 Mar;6(2):290-299.
Title:	Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
Author:	Berger, Andreas W\|Raedler, Katja\|Langner, Cord\|Ludwig, Leopold\|Dikopoulos, Nektarios\|Becker, Karl F\|Slotta-Huspenina, Julia\|Quante, Michael\|Schwerdel, Daniel\|Perkhofer, Lukas\|Kleger, Alexander\|Zizer, Eugen\|Oswald, Franz\|Seufferlein, Thomas\|Meining, Alexan
PMID:	29511559

3285.
Journal:	Cell Rep. 2018 Mar 6;22(10):2677-2689.
Title:	Targeting a Sirt5-Positive Subpopulation Overcomes Multidrug Resistance in Wild-Type Kras Colorectal Carcinomas.
Author:	Du, ZunGuo\|Liu, XiuJuan\|Chen, Tao\|Gao, WenChao\|Wu, ZhengMing\|Hu, ZhiQian\|Wei, Dong\|Gao, ChunFang\|Li, QingQuan
PMID:	29514096

3286.
Journal:	Ann Oncol. 2018 May 1;29(5):1227-1234.
Title:	CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer.
Author:	Smeby, J\|Sveen, A\|Merok, M A\|Danielsen, S A\|Eilertsen, I A\|Guren, M G\|Dienstmann, R\|Nesbakken, A\|Lothe, R A
PMID:	29518181

3287.
Journal:	Oncologist. 2018 Aug;23(8):912-918.
Title:	Phase II Study of Preoperative Treatment with External Radiotherapy Plus Panitumumab in Low-Risk, Locally Advanced Rectal Cancer (RaP Study/STAR-03).
Author:	Pinto, Carmine\|Di Bisceglie, Maurizio\|Di Fabio, Francesca\|Bochicchio, Annamaria\|Latiano, Tiziana\|Cordio, Stefano\|Rosati, Gerardo\|Aschele, Carlo\|Marino, Antonella\|Bergamo, Francesca\|Bustreo, Sara\|Frassineti, Luca\|Ciardiello, Fortunato\|Damato, Angela\|Giaqui
PMID:	29523646

3288.
Journal:	Surg Today. 2018 Aug;48(8):765-772.
Title:	APC:T1556fs and STK11 mutations in duodenal adenomas and adenocarcinomas.
Author:	Kojima, Yohei\|Ohtsuka, Kouki\|Ohnishi, Hiroaki\|Abe, Nobutsugu\|Furuse, Junji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	29525853

3289.
Journal:	Clin Colorectal Cancer. 2018 Jun;17(2):e331-e352.
Title:	Phosphorylation of p70 Ribosomal Protein S6 Kinase beta-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.
Author:	Wiesweg, Marcel\|Reis, Henning\|Koster, Tobias\|Goetz, Moritz\|Worm, Karl\|Herold, Thomas\|Paul, Andreas\|Dechene, Alexander\|Schumacher, Brigitte\|Markus, Peter\|Virchow, Isabel\|Kostbade, Karina\|Wolf, Nathalie\|Zaun, Gregor\|Metzenmacher, Martin\|Schmid, Kurt W\|Schul
PMID:	29526493

3290.
Journal:	Oncol Lett. 2018 Apr;15(4):4365-4375.
Title:	Monitoring colorectal cancer following surgery using plasma circulating tumor DNA.
Author:	Sun, Xiao\|Huang, Tanxiao\|Cheng, Fangsheng\|Huang, Kaibing\|Liu, Ming\|He, Wan\|Li, Mingwei\|Zhang, Xiaoni\|Xu, Mingyan\|Chen, Shifu\|Xia, Ligang
PMID:	29541205

3291.
Journal:	Mol Cancer Ther. 2018 May;17(5):977-987.
Title:	A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-kappaB Signaling in KRAS-Mutant Colon Cancer Cells.
Author:	Inoue, Akira\|Mizushima, Tsunekazu\|Wu, Xin\|Okuzaki, Daisuke\|Kambara, Nanami\|Ishikawa, Sho\|Wang, Jiaqi\|Qian, Yamin\|Hirose, Haruka\|Yokoyama, Yuhki\|Ikeshima, Ryo\|Hiraki, Masayuki\|Miyoshi, Norikatsu\|Takahashi, Hidekazu\|Haraguchi, Naotsugu\|Hata, Taishi\|Matsuda,
PMID:	29545333

3292.
Journal:	Carcinogenesis. 2018 May 3;39(5):708-718.
Title:	The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.
Author:	Wang, Xiangfeng\|Fang, Hu\|Cheng, Yong\|Li, Lin\|Sun, Xiaohui\|Fu, Tao\|Huang, Peide\|Zhang, Anping\|Feng, Zhimin\|Li, Chunxue\|Huang, Xuanlin\|Li, Guangyan\|Du, Peina\|Yang, Huanming\|Fang, Xiaodong\|Li, Fan\|Gao, Qiang\|Liu, Baohua
PMID:	29546405

3293.
Journal:	Am J Med Sci. 2018 Mar;355(3):220-227.
Title:	Use of Liquid Biopsy in Monitoring Colorectal Cancer Progression Shows Strong Clinical Correlation.
Author:	Sun, Qiushi\|Liu, Yuan\|Liu, Bo\|Liu, Yingying
PMID:	29549923

3294.
Journal:	Oncogene. 2018 Jun;37(24):3301-3316.
Title:	beta-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy.
Author:	Saponaro, Concetta\|Sergio, Sara\|Coluccia, Antonio\|De Luca, Maria\|La Regina, Giuseppe\|Mologni, Luca\|Famiglini, Valeria\|Naccarato, Valentina\|Bonetti, Daniela\|Gautier, Candice\|Gianni, Stefano\|Vergara, Daniele\|Salzet, Michel\|Fournier, Isabelle\|Bucci, Cecilia\|
PMID:	29551770

3295.
Journal:	Theranostics. 2018 Feb 12;8(6):1678-1689.
Title:	Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients.
Author:	Li, Xiaozhou\|Yang, Tianyue\|Li, Caesar Siqi\|Song, Youtao\|Lou, Hong\|Guan, Dagang\|Jin, Lili
PMID:	29556349

3296.
Journal:	Oncogene. 2018 Jun;37(25):3440-3455.
Title:	Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Author:	Chu, Po-Chen\|Lin, Peng-Chan\|Wu, Hsing-Yu\|Lin, Kuen-Tyng\|Wu, Christina\|Bekaii-Saab, Tanios\|Lin, Yih-Jyh\|Lee, Chung-Ta\|Lee, Jeng-Chang\|Chen, Ching-Shih
PMID:	29559746

3297.
Journal:	Genes Chromosomes Cancer. 2018 Jul;57(7):366-376.
Title:	Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.
Author:	Wolff, Roger K\|Hoffman, Michael D\|Wolff, Erica C\|Herrick, Jennifer S\|Sakoda, Lori C\|Samowitz, Wade S\|Slattery, Martha L
PMID:	29575536

3298.
Journal:	Sheng Wu Gong Cheng Xue Bao. 2018 Mar 25;34(3):407-420.
Title:	[Detection of KRAS mutation in colorectal cancer patients' cfDNA with droplet digital PCR].
Author:	Luo, Yuwen\|Li, Yao
PMID:	29577691

3299.
Journal:	Cancer Biol Ther. 2018 Aug 3;19(8):659-663.
Title:	Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
Author:	Baretti, M\|Personeni, N\|Destro, A\|Santoro, A\|Rimassa, L
PMID:	29580164

3300.
Journal:	World J Surg Oncol. 2018 Mar 27;16(1):67.
Title:	FOLFIRI plus panitumumab in the treatment of wild-type KRAS and wild-type NRAS metastatic colorectal cancer.
Author:	Geredeli, Caglayan\|Yasar, Nurgul
PMID:	29587749

3301.
Journal:	JAMA Oncol. 2018 Jun 1;4(6):806-813.
Title:	Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.
Author:	Hampel, Heather\|Pearlman, Rachel\|Beightol, Mallory\|Zhao, Weiqiang\|Jones, Daniel\|Frankel, Wendy L\|Goodfellow, Paul J\|Yilmaz, Ahmet\|Miller, Kristin\|Bacher, Jason\|Jacobson, Angela\|Paskett, Electra\|Shields, Peter G\|Goldberg, Richard M\|de la Chapelle, Albert\|S
PMID:	29596542

3302.
Journal:	Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4140-4145.
Title:	Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk.
Author:	Ntai, Ioanna\|Fornelli, Luca\|DeHart, Caroline J\|Hutton, Josiah E\|Doubleday, Peter F\|LeDuc, Richard D\|van Nispen, Alexandra J\|Fellers, Ryan T\|Whiteley, Gordon\|Boja, Emily S\|Rodriguez, Henry\|Kelleher, Neil L
PMID:	29610327

3303.
Journal:	Evid Based Complement Alternat Med. 2018 Feb 12;2018:6517034.
Title:	A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.
Author:	Liu, Xinkui\|Wu, Jiarui\|Zhang, Dan\|Wang, Kaihuan\|Duan, Xiaojiao\|Zhang, Xiaomeng
PMID:	29619072

3304.
Journal:	Genes Nutr. 2018 Apr 2;13:8.
Title:	Omega-3 fatty acid DHA modulates p53, survivin, and microRNA-16-1 expression in KRAS-mutant colorectal cancer stem-like cells.
Author:	Sam, Mohammad Reza\|Tavakoli-Mehr, Mohammad\|Safaralizadeh, Reza
PMID:	29619114

3305.
Journal:	Cesk Patol. 2018 Spring;54(1):17-21.
Title:	[Prediction of EGFR blockade responses in metastatic colorectal carcinoma].
Author:	Fabian, Pavel\|Nemecek, Radim
PMID:	29631407

3306.
Journal:	Oncotarget. 2018 Feb 15;9(20):15302-15311.
Title:	Differential clinicopathological and molecular features within late-onset colorectal cancer according to tumor location.
Author:	Brandariz, Lorena\|Arriba, Maria\|Garcia, Juan Luis\|Cano, Juana Maria\|Rueda, Daniel\|Rubio, Eduardo\|Rodriguez, Yolanda\|Perez, Jessica\|Vivas, Alfredo\|Sanchez, Carmen\|Tapial, Sandra\|Pena, Laura\|Garcia-Arranz, Mariano\|Garcia-Olmo, Damian\|Urioste, Miguel\|Gonzale
PMID:	29632645

3307.
Journal:	Gastroenterol Res Pract. 2018 Jan 31;2018:4585802.
Title:	Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Yang, Dongyang\|Ma, Dong
PMID:	29643917

3308.
Journal:	Pathol Res Pract. 2018 May;214(5):720-726.
Title:	Phenotypic and genotypic differences in colorectal carcinoma among Caucasians, Asians, and Hispanics lack statistical significance.
Author:	Hoffman, Sara J\|Wu, Mark Li-Cheng
PMID:	29650442

3309.
Journal:	Oncotarget. 2018 Mar 27;9(23):16477-16488.
Title:	Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles.
Author:	Mori, Yoshiko\|Nyuya, Akihiro\|Yasui, Kazuya\|Toshima, Toshiaki\|Kawai, Takashi\|Taniguchi, Fumitaka\|Kimura, Keisuke\|Inada, Ryo\|Nishizaki, Masahiko\|Haraga, Junko\|Nakamura, Keiichiro\|Umeda, Yuzo\|Kishimoto, Hiroyuki\|Fujiwara, Toshiyoshi\|Katata, Yosuke\|Yamaguchi,
PMID:	29662660

3310.
Journal:	Sci Rep. 2018 Apr 17;8(1):6076.
Title:	Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.
Author:	Guo, Fang\|Gong, Hai\|Zhao, Huanhuan\|Chen, Jing\|Zhang, Yiming\|Zhang, Lihua\|Shi, Xin\|Zhang, Aifeng\|Jin, Hui\|Zhang, Jianqiong\|He, Youji
PMID:	29666387

3311.
Journal:	Middle East J Dig Dis. 2018 Jan;10(1):18-23.
Title:	Frequency of NRAS Gene Mutation in Wild Type KRAS and BRAF Colorectal Cancers; a Single Center Study.
Author:	Momenzadeh, Hooria\|Mirzai, Mitra\|Jowkar, Zahra\|Geramizadeh, Bita
PMID:	29682243

3312.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):615-617.
Title:	Identification of key pathways and genes in mutant KRAS colorectal cancer by integrated bioinformatics analysis.
Author:	Zhang, Haiyan\|Zhang, Xiaoming\|Chen, Xiaodong\|Zhang, Wei\|Xian, Jiang\|Zhou, Xia\|Yang, Jun\|Wang, Jie
PMID:	29688256

3313.
Journal:	PLoS One. 2018 Apr 25;13(4):e0196233.
Title:	One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status.
Author:	Myte, Robin\|Gylling, Bjorn\|Haggstrom, Jenny\|Schneede, Jorn\|Lofgren-Burstrom, Anna\|Huyghe, Jeroen R\|Hallmans, Goran\|Meyer, Klaus\|Johansson, Ingegerd\|Ueland, Per Magne\|Palmqvist, Richard\|Van Guelpen, Bethany
PMID:	29694444

3314.
Journal:	BMC Med Genomics. 2018 Apr 20;11(Suppl 2):29.
Title:	Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes.
Author:	Rhee, Je-Keun\|Kim, Tae-Min
PMID:	29697365

3315.
Journal:	J Clin Pathol. 2018 Aug;71(8):743-744.
Title:	Evaluation of the correlation between KRAS mutated allele frequency and pathologist tumorous nuclei percentage assessment in colorectal cancer suggests a role for zygosity status.
Author:	Libbrecht, Louis\|Baldin, Pamela\|Dekairelle, Anne-France\|Jouret-Mourin, Anne
PMID:	29703759

3316.
Journal:	Virchows Arch. 2018 Jun;472(6):959-968.
Title:	Performance validation of an amplicon-based targeted next-generation sequencing assay and mutation profiling of 648 Chinese colorectal cancer patients.
Author:	Wang, Yajian\|Liu, Haijing\|Hou, Yingyong\|Zhou, Xiaoyan\|Liang, Li\|Zhang, Zhihong\|Shi, Huaiyin\|Xu, Sanpeng\|Hu, Peizhen\|Zheng, Zuyu\|Liu, Rui\|Tang, Tingdong\|Ye, Feng\|Liang, Zhiyong\|Bu, Hong
PMID:	29705968

3317.
Journal:	Can J Gastroenterol Hepatol. 2018 Mar 7;2018:4248971.
Title:	RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients.
Author:	Yao, Jiannan\|Zang, Wanchun\|Ge, Yang\|Weygant, Nathaniel\|Yu, Pan\|Li, Lei\|Rao, Guanhua\|Jiang, Zhi\|Yan, Rui\|He, Linjia\|Yu, Yang\|Jin, Mulan\|Cheng, Gang\|An, Guangyu
PMID:	29707525

3318.
Journal:	Anticancer Res. 2018 May;38(5):2891-2895.
Title:	Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Author:	Deshwar, Amar\|Margonis, Georgios Antonios\|Andreatos, Nikolaos\|Barbon, Carlotta\|Wang, Jaeyun\|Buettner, Stefan\|Wagner, Doris\|Sasaki, Kazunari\|Beer, Andrea\|Loes, Inger Marie\|Pikoulis, Emmanouil\|Damaskos, Christos\|Garmpis, Nikolaos\|Kamphues, Karsten\|He, Jin\|K
PMID:	29715113

3319.
Journal:	J Natl Cancer Inst. 2018 Apr 27. pii: 4989438.
Title:	Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.
Author:	Loree, Jonathan M\|Bailey, Ann M\|Johnson, Amber M\|Yu, Yao\|Wu, Wenhui\|Bristow, Christopher A\|Davis, Jennifer S\|Shaw, Kenna R\|Broaddus, Russell\|Banks, Kimberly C\|Lanman, Richard B\|Meric-Bernstam, Funda\|Overman, Michael J\|Kopetz, Scott\|Raghav, Kanwal
PMID:	29718453

3320.
Journal:	Clin Colon Rectal Surg. 2018 May;31(3):147-152.
Title:	Update on Sporadic Colorectal Cancer Genetics.
Author:	Hardiman, Karin M
PMID:	29720900

3321.
Journal:	Oncotarget. 2018 Apr 6;9(26):18664.
Title:	Correction: New localization and function of calpain-2 in nucleoli of colorectal cancer cells in ribosomal biogenesis: effect of KRAS status.
Author:	Telechea-Fernandez, Marcelino\|Rodriguez-Fernandez, Lucia\|Garcia, Concha\|Zaragoza, Rosa\|Vina, Juan R\|Cervantes, Andres\|Garcia-Trevijano, Elena R
PMID:	29722369

3322.
Journal:	Exp Ther Med. 2018 May;15(5):4229-4242.
Title:	Upregulation of c-mesenchymal epithelial transition expression and RAS mutations are associated with late lung metastasis and poor prognosis in colorectal carcinoma.
Author:	Liu, Jianhua\|Zeng, Weiqiang\|Huang, Chengzhi\|Wang, Junjiang\|Xu, Lishu\|Ma, Dong
PMID:	29725370

3323.
Journal:	Histopathology. 2018 Sep;73(3):444-453.
Title:	Immunohistochemical and genetic characteristics of a colorectal mucin-rich variant of traditional serrated adenoma.
Author:	Hiromoto, Takafumi\|Murakami, Takashi\|Akazawa, Yoichi\|Sasahara, Noriko\|Saito, Tsuyoshi\|Sakamoto, Naoto\|Mitomi, Hiroyuki\|Nagahara, Akihito\|Yao, Takashi
PMID:	29729192

3324.
Journal:	Pathol Res Pract. 2018 Jun;214(6):826-834.
Title:	Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author:	Tsikalakis, Spyridon\|Chatziandreou, Ilenia\|Michalopoulos, Nikolaos V\|Theodoropoulos, Georgios E\|Sakellariou, Stratigoula\|Korkolopoulou, Penelope\|Patsouris, Efstratios\|Saetta, Angelica A
PMID:	29731264

3325.
Journal:	Oncogene. 2018 Aug;37(32):4372-4384.
Title:	A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype.
Author:	Kota, Smitha\|Hou, Shurong\|Guerrant, William\|Madoux, Franck\|Troutman, Scott\|Fernandez-Vega, Virneliz\|Alekseeva, Nina\|Madala, Neeharika\|Scampavia, Louis\|Kissil, Joseph\|Spicer, Timothy P
PMID:	29743592

3326.
Journal:	J BUON. 2018 Mar-Apr;23(2):286-289.
Title:	Site-specific use of molecular markers could be a promising prognostic tool in colorectal cancer.
Author:	Papagiorgis, Petros\|Zizi-Sermbetzoglou, Adamantia\|Chaniotis, Dimitrios\|Thalassinos, Nikolaos\|Tziakou, Paraskevi
PMID:	29745066

3327.
Journal:	Cell Calcium. 2018 Jun;72:70-80.
Title:	Oncogenic KRAS suppresses store-operated Ca(2+) entry and ICRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines.
Author:	Pierro, Cristina\|Zhang, Xuexin\|Kankeu, Cynthia\|Trebak, Mohamed\|Bootman, Martin D\|Roderick, H Llewelyn
PMID:	29748135

3328.
Journal:	Oncogene. 2018 May 14. pii: 10.1038/s41388-018-0289-x.
Title:	Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer.
Author:	Knickelbein, Kyle\|Tong, Jingshan\|Chen, Dongshi\|Wang, Yi-Jun\|Misale, Sandra\|Bardelli, Alberto\|Yu, Jian\|Zhang, Lin
PMID:	29755130

3329.
Journal:	Oncotarget. 2018 Apr 17;9(29):20426-20438.
Title:	Hotspot KRAS exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells.
Author:	Wong, Hung Lai\|Ng, Lawrence Po Wah\|Koh, Su Pin\|Chan, Lawrence Wing Chi\|Wong, Evelyn Yin Kwan\|Xue, Vivian Weiwen\|Tsang, Hin Fung Andy\|Chan, Amanda Kit Ching\|Chiu, Ka Yue\|Cheuk, Wah\|Wong, Sze Chuen Cesar
PMID:	29755662

3330.
Journal:	Oncotarget. 2018 Apr 17;9(29):20578-20589.
Title:	Role of epigenetic factors in the selection of the alternative splicing isoforms of human KRAS in colorectal cancer cell lines.
Author:	Riffo-Campos, Angela L\|Gimeno-Valiente, Francisco\|Rodriguez, Fernanda M\|Cervantes, Andres\|Lopez-Rodas, Gerardo\|Franco, Luis\|Castillo, Josefa
PMID:	29755673

3331.
Journal:	Oncotarget. 2018 Apr 17;9(29):20761-20768.
Title:	Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience.
Author:	D'Haene, Nicky\|Fontanges, Quitterie\|De Neve, Nancy\|Blanchard, Oriane\|Melendez, Barbara\|Delos, Monique\|Dehou, Marie-Francoise\|Maris, Calliope\|Nagy, Nathalie\|Rousseau, Emmanuel\|Vandenhove, Josse\|Gilles, Andre\|De Prez, Carine\|Verset, Laurine\|Van Craynest, Ma
PMID:	29755687

3332.
Journal:	Gastroenterology. 2018 Sep;155(3):844-851.
Title:	Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.
Author:	Ten Broeke, Sanne W\|van Bavel, Tom C\|Jansen, Anne M L\|Gomez-Garcia, Encarnca\|Hes, Frederik J\|van Hest, Liselot P\|Letteboer, Tom G W\|Olderode-Berends, Maran J W\|Ruano, Dina\|Spruijt, Liesbeth\|Suerink, Manon\|Tops, Carli M\|van Eijk, Ronald\|Morreau, Hans\|van W
PMID:	29758216

3333.
Journal:	Crit Rev Oncol Hematol. 2018 Jun;126:121-128.
Title:	The role of heme iron molecules derived from red and processed meat in the pathogenesis of colorectal carcinoma.
Author:	Gamage, S M K\|Dissabandara, Lakal\|Lam, Alfred King-Yin\|Gopalan, Vinod
PMID:	29759553

3334.
Journal:	Sci Rep. 2018 May 14;8(1):7522.
Title:	Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.
Author:	Jacobsen, Annika\|Bosch, Linda J W\|Martens-de Kemp, Sanne R\|Carvalho, Beatriz\|Sillars-Hardebol, Anke H\|Dobson, Richard J\|de Rinaldis, Emanuele\|Meijer, Gerrit A\|Abeln, Sanne\|Heringa, Jaap\|Fijneman, Remond J A\|Feenstra, K Anton
PMID:	29760449

3335.
Journal:	Oncotarget. 2018 Apr 20;9(30):21122-21131.
Title:	Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy).
Author:	Garcia, Jessica\|Forestier, Julien\|Dusserre, Eric\|Wozny, Anne-Sophie\|Geiguer, Florence\|Merle, Patrick\|Tissot, Claire\|Ferraro-Peyret, Carole\|Jones, Frederick S\|Edelstein, Daniel L\|Cheynet, Valerie\|Bardel, Claire\|Vilchez, Gaelle\|Xu, Zhenyu\|Bringuier, Pierre
PMID:	29765524

3336.
Journal:	Jpn J Clin Oncol. 2018 Jul 1;48(7):609-618.
Title:	Clinicopathological and molecular differences between right-sided and left-sided colorectal cancer in Japanese patients.
Author:	Natsume, Soichiro\|Yamaguchi, Tatsuro\|Takao, Misato\|Iijima, Takeru\|Wakaume, Rika\|Takahashi, Keiichi\|Matsumoto, Hiroshi\|Nakano, Daisuke\|Horiguchi, Shin-Ichiro\|Koizumi, Koichi\|Miyaki, Michiko
PMID:	29767751

3337.
Journal:	Cancer Res. 2018 Jul 15;78(14):3899-3912.
Title:	Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition.
Author:	Fuentes, Natividad R\|Mlih, Mohamed\|Barhoumi, Rola\|Fan, Yang-Yi\|Hardin, Paul\|Steele, Trevor J\|Behmer, Spencer\|Prior, Ian A\|Karpac, Jason\|Chapkin, Robert S
PMID:	29769200

3338.
Journal:	Clin Lab Med. 2018 Jun;38(2):311-342.
Title:	Molecular Diagnostics in Colorectal Carcinoma: Advances and Applications for 2018.
Author:	Bhalla, Amarpreet\|Zulfiqar, Muhammad\|Bluth, Martin H
PMID:	29776633

3339.
Journal:	Ann Surg. 2018 May 17.
Title:	Anatomical Resections Improve Survival Following Lung Metastasectomy of Colorectal Cancer Harboring KRAS Mutations.
Author:	Renaud, Stephane\|Seitlinger, Joseph\|Lawati, Yaseen Al\|Guerrera, Francesco\|Falcoz, Pierre-Emmanuel\|Massard, Gilbert\|Ferri, Lorenzo\|Spicer, Jonathan
PMID:	29781848

3340.
Journal:	Inflamm Bowel Dis. 2018 Jul 12;24(8):1780-1790.
Title:	Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation.
Author:	Hartman, Douglas J\|Binion, David G\|Regueiro, Miguel D\|Miller, Caitlyn\|Herbst, Cameron\|Pai, Reetesh K
PMID:	29788391

3341.
Journal:	Neoplasma. 2018 Mar 14;65(3):415-424.
Title:	Novel insights into transcriptional dysregulation in colorectal cancer.
Author:	Feodorova, Y\|Tashkova, D\|Koev, I\|Todorov, A\|Kostov, G\|Simitchiev, K\|Belovejdov, V\|Dimov, R\|Sarafian, V
PMID:	29788743

3342.
Journal:	Arch Pathol Lab Med. 2018 May 23.
Title:	Colorectal Liver Metastases: A Pathologist's Guide to Creating an Informative Report and Improving Patient Care.
Author:	Moreno Prats, Mariana\|Sasatomi, Eizaburo\|Stevenson, Heather L
PMID:	29790787

3343.
Journal:	Gynecol Oncol. 2018 Jul;150(1):127-135.
Title:	Massively parallel sequencing analysis of mucinous ovarian carcinomas: genomic profiling and differential diagnoses.
Author:	Mueller, Jennifer J\|Schlappe, Brooke A\|Kumar, Rahul\|Olvera, Narciso\|Dao, Fanny\|Abu-Rustum, Nadeem\|Aghajanian, Carol\|DeLair, Deborah\|Hussein, Yaser R\|Soslow, Robert A\|Levine, Douglas A\|Weigelt, Britta
PMID:	29793804

3344.
Journal:	Oncotarget. 2018 May 1;9(33):22895-22906.
Title:	Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers.
Author:	Sugai, Tamotsu\|Eizuka, Makoto\|Habano, Wataru\|Fujita, Yasuko\|Sato, Ayaka\|Sugimoto, Ryo\|Otsuka, Kouki\|Yamamoto, Eiichiro\|Matsumoto, Takayuki\|Suzuki, Hiromu
PMID:	29796160

3345.
Journal:	JAMA Surg. 2018 Jul 18;153(7):e180996.
Title:	Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
Author:	Margonis, Georgios Antonios\|Buettner, Stefan\|Andreatos, Nikolaos\|Kim, Yuhree\|Wagner, Doris\|Sasaki, Kazunari\|Beer, Andrea\|Schwarz, Christoph\|Loes, Inger Marie\|Smolle, Maria\|Kamphues, Carsten\|He, Jin\|Pawlik, Timothy M\|Kaczirek, Klaus\|Poultsides, George\|Lonn
PMID:	29799910

3346.
Journal:	Clin Transl Oncol. 2018 May 25. pii: 10.1007/s12094-018-1874-8.
Title:	Molecular subtypes in early colorectal cancer associated with clinical features and patient prognosis.
Author:	Gil-Raga, M\|Jantus-Lewintre, E\|Gallach, S\|Giner-Bosch, V\|Frangi-Caregnato, A\|Safont-Aguilera, M J\|Garde-Noguera, J\|Zorraquino-Pina, E\|Garcia-Martinez, M\|Camps-Herrero, C
PMID:	29802524

3347.
Journal:	J Cancer. 2018 Apr 19;9(10):1791-1796.
Title:	The impact of microsatellite instability status and sidedness of the primary tumor on the effect of bevacizumab-containing chemotherapy in patients with metastatic colorectal cancer.
Author:	Kim, Seung Tae\|Kim, Hee Kyung\|Lee, Jeeyun\|Park, Se Hoon\|Lim, Ho Yeong\|Park, Young Suk\|Kang, Won Ki\|Park, Joon Oh
PMID:	29805705

3348.
Journal:	Nat Med. 2018 Jul;24(7):961-967.
Title:	SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.
Author:	Mainardi, Sara\|Mulero-Sanchez, Antonio\|Prahallad, Anirudh\|Germano, Giovanni\|Bosma, Astrid\|Krimpenfort, Paul\|Lieftink, Cor\|Steinberg, Jeffrey D\|de Wit, Niels\|Goncalves-Ribeiro, Samuel\|Nadal, Ernest\|Bardelli, Alberto\|Villanueva, Alberto\|Bernards, Rene
PMID:	29808006

3349.
Journal:	Oncotarget. 2018 May 8;9(35):24081-24096.
Title:	Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients.
Author:	Sayagues, Jose Maria\|Del Carmen, Sofia\|Del Mar Abad, Maria\|Corchete, Luis Antonio\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Baldeon, Maria Jesus\|Cruz, Juan Jesus\|Alcazar, Jose Antonio\|Angoso, Maria\|Gonzalez, Marcos\|Garcia, Jacinto\|Munoz-Bellvis, Luis\|Orfa
PMID:	29844874

3350.
Journal:	J Cell Mol Med. 2018 Sep;22(9):4097-4105.
Title:	In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer.
Author:	Wei, Ran\|Wong, Janet Pik Ching\|Lyu, Peng\|Xi, Xinping\|Tong, Olivia\|Zhang, Shu-Dong\|Yuen, Hiu Fung\|Shirasawa, Senji\|Kwok, Hang Fai
PMID:	29851214

3351.
Journal:	Oncotarget. 2018 Apr 27;9(32):22749-22768.
Title:	Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.
Author:	Oliveira, Duarte Mendes\|Mirante, Teresa\|Mignogna, Chiara\|Scrima, Marianna\|Migliozzi, Simona\|Rocco, Gaetano\|Franco, Renato\|Corcione, Francesco\|Viglietto, Giuseppe\|Malanga, Donatella\|Rizzuto, Antonia
PMID:	29854313

3352.
Journal:	Med Oncol. 2018 May 31;35(7):101.
Title:	Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping.
Author:	Papaxoinis, George\|Kotoula, Vassiliki\|Giannoulatou, Eleni\|Koliou, Georgia-Angeliki\|Karavasilis, Vasilios\|Lakis, Sotirios\|Koureas, Andreas\|Bobos, Mattheos\|Chalaralambous, Elpida\|Daskalaki, Emily\|Chatzopoulos, Kyriakos\|Tsironis, George\|Pazarli, Elisavet\|Chr
PMID:	29855806

3353.
Journal:	NPJ Precis Oncol. 2018 Feb 20;2(1):5.
Title:	Interaction between Wnt/beta-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of beta-catenin and RAS by targeting the Wnt/beta-catenin pathway.
Author:	Jeong, Woo-Jeong\|Ro, Eun Ji\|Choi, Kang-Yell
PMID:	29872723

3354.
Journal:	Cancer Sci. 2018 Jun;109(6):2074-2079.
Title:	Japanese Society of Medical Oncology Clinical Guidelines: Molecular Testing for Colorectal Cancer Treatment, Third Edition.
Author:	Yamazaki, Kentaro\|Taniguchi, Hiroya\|Yoshino, Takayuki\|Akagi, Kiwamu\|Ishida, Hideyuki\|Ebi, Hiromichi\|Nakatani, Kaname\|Muro, Kei\|Yatabe, Yasushi\|Yamaguchi, Kensei\|Tsuchihara, Katsuya
PMID:	29873882

3355.
Journal:	PLoS One. 2018 Jun 7;13(6):e0198795.
Title:	Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues.
Author:	Chat-Uthai, Nunthawut\|Vejvisithsakul, Pichpisith\|Udommethaporn, Sutthirat\|Meesiri, Puttarakun\|Danthanawanit, Chetiya\|Wongchai, Yannawan\|Teerapakpinyo, Chinachote\|Shuangshoti, Shanop\|Poungvarin, Naravat
PMID:	29879227

3356.
Journal:	PLoS One. 2018 Jun 8;13(6):e0197327.
Title:	Evaluation of the detection of Toll-like receptors (TLRs) in cancer development and progression in patients with colorectal cancer.
Author:	Messaritakis, Ippokratis\|Stogiannitsi, Maria\|Koulouridi, Asimina\|Sfakianaki, Maria\|Voutsina, Alexandra\|Sotiriou, Afroditi\|Athanasakis, Elias\|Xynos, Evangelos\|Mavroudis, Dimitris\|Tzardi, Maria\|Souglakos, John
PMID:	29883450

3357.
Journal:	Exp Mol Med. 2018 Jun 6;50(6):71.
Title:	Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of beta-catenin signaling.
Author:	Shin, Wookjin\|Lee, Sang-Kyu\|Hwang, Jeong-Ha\|Park, Jong-Chan\|Cho, Yong-Hee\|Ro, Eun Ji\|Song, Yeonhwa\|Seo, Haeng Ran\|Choi, Kang-Yell
PMID:	29884842

3358.
Journal:	Mol Oncol. 2018 Aug;12(8):1398-1409.
Title:	Macrophage migration inhibitory factor promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells.
Author:	Cheon, Seul-Ki\|Kim, Hwang-Phill\|Park, Ye-Lim\|Jang, Jee-Eun\|Lim, Yoojoo\|Song, Sang-Hyun\|Han, Sae-Won\|Kim, Tae-You
PMID:	29896883

3359.
Journal:	Oncoimmunology. 2018 Mar 19;7(7):e1442999.
Title:	TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas.
Author:	Hamada, Tsuyoshi\|Soong, Thing Rinda\|Masugi, Yohei\|Kosumi, Keisuke\|Nowak, Jonathan A\|da Silva, Annacarolina\|Mu, Xinmeng Jasmine\|Twombly, Tyler S\|Koh, Hideo\|Yang, Juhong\|Song, Mingyang\|Liu, Li\|Gu, Mancang\|Shi, Yan\|Nosho, Katsuhiko\|Morikawa, Teppei\|Inamura,
PMID:	29900052

3360.
Journal:	Clin Chem. 2018 Sep;64(9):1296-1307.
Title:	Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine.
Author:	Whale, Alexandra S\|Jones, Gerwyn M\|Pavsic, Jernej\|Dreo, Tanja\|Redshaw, Nicholas\|Akyurek, Sema\|Akgoz, Muslum\|Divieto, Carla\|Sassi, Maria Paola\|He, Hua-Jun\|Cole, Kenneth D\|Bae, Young-Kyung\|Park, Sang-Ryoul\|Deprez, Liesbet\|Corbisier, Philippe\|Garrigou, Sonia
PMID:	29903874

3361.
Journal:	Sci Rep. 2018 Jun 15;8(1):9204.
Title:	Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Author:	Fritsche-Guenther, Raphaela\|Zasada, Christin\|Mastrobuoni, Guido\|Royla, Nadine\|Rainer, Roman\|Rossner, Florian\|Pietzke, Matthias\|Klipp, Edda\|Sers, Christine\|Kempa, Stefan
PMID:	29907857

3362.
Journal:	Cancer Sci. 2018 Aug;109(8):2567-2575.
Title:	Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.
Author:	Osumi, Hiroki\|Shinozaki, Eiji\|Mashima, Tetsuo\|Wakatsuki, Takeru\|Suenaga, Mitsukuni\|Ichimura, Takashi\|Ogura, Mariko\|Ota, Yumiko\|Nakayama, Izuma\|Takahari, Daisuke\|Chin, Keisho\|Miki, Yoshio\|Yamaguchi, Kensei
PMID:	29908105

3363.
Journal:	Ann Transl Med. 2018 May;6(9):159.
Title:	Colorectal cancer genomics and designing rational trials.
Author:	Mondaca, Sebastian\|Yaeger, Rona
PMID:	29911107

3364.
Journal:	Sci Rep. 2018 Jun 18;8(1):9296.
Title:	PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation.
Author:	Davis, Thomas B\|Yang, Mingli\|Schell, Michael J\|Wang, Heiman\|Ma, Le\|Pledger, W Jack\|Yeatman, Timothy J
PMID:	29915291

3365.
Journal:	Curr Probl Cancer. 2018 May 25. pii: S0147-0272(18)30038-2.
Title:	Common KRAS and NRAS gene mutations in sporadic colorectal cancer in Northeastern Iranian patients.
Author:	Hamzehzadeh, Leila\|Khadangi, Fatemeh\|Ghayoor Karimiani, Ehsan\|Pasdar, Alireza\|Kerachian, Mohammad Amin
PMID:	29921458

3366.
Journal:	Per Med. 2018 Jul 1;15(4):319-327.
Title:	The interference between oxaliplatin & anti-EGFR therapies: a different hypothesis to explain the 'unexplainable'.
Author:	Basso, Michele\|Dadduzio, Vincenzo\|Rossi, Sabrina\|D'Argento, Ettore\|Strippoli, Antonia\|Di Salvatore, Mariantonietta\|Orlandi, Armando\|Zurlo, Valeria\|Di Noia, Vincenzo\|Barone, Carlo
PMID:	29927360

3367.
Journal:	Surg Oncol. 2018 Jun;27(2):280-288.
Title:	Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.
Author:	Tsilimigras, Diamantis I\|Ntanasis-Stathopoulos, Ioannis\|Bagante, Fabio\|Moris, Demetrios\|Cloyd, Jordan\|Spartalis, Eleftherios\|Pawlik, Timothy M
PMID:	29937183

3368.
Journal:	Oncotarget. 2018 Jun 8;9(44):27412-27422.
Title:	The landscape of somatic mutation in sporadic Chinese colorectal cancer.
Author:	Liu, Zhe\|Yang, Chao\|Li, Xiangchun\|Luo, Wen\|Roy, Bhaskar\|Xiong, Teng\|Zhang, Xiuqing\|Yang, Huanming\|Wang, Jian\|Ye, Zhenhao\|Chen, Yang\|Song, Jinghe\|Ma, Shuai\|Zhou, Yong\|Yang, Min\|Fang, Xiaodong\|Du, Jie
PMID:	29937994

3369.
Journal:	Rom J Morphol Embryol. 2018;59(1):121-129.
Title:	Mutational status of KRAS and MMR genes in a series of colorectal carcinoma cases.
Author:	Cionca, Florina Lucia\|Dobre, Maria\|Dobrea, Camelia Marioara\|Iosif, Cristina Ileana\|Comanescu, Maria Victoria\|Ardeleanu, Carmen Maria
PMID:	29940619

3370.
Journal:	J Exp Clin Cancer Res. 2018 Jun 26;37(1):124.
Title:	Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).
Author:	Gasparello, Jessica\|Allegretti, Matteo\|Tremante, Elisa\|Fabbri, Enrica\|Amoreo, Carla Azzurra\|Romania, Paolo\|Melucci, Elisa\|Messana, Katia\|Borgatti, Monica\|Giacomini, Patrizio\|Gambari, Roberto\|Finotti, Alessia
PMID:	29941002

3371.
Journal:	BMC Cancer. 2018 Jun 27;18(1):695.
Title:	Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author:	Molnar, Bela\|Galamb, Orsolya\|Peterfia, Balint\|Wichmann, Barnabas\|Csabai, Istvan\|Bodor, Andras\|Kalmar, Alexandra\|Szigeti, Krisztina Andrea\|Bartak, Barbara Kinga\|Nagy, Zsofia Brigitta\|Valcz, Gabor\|Patai, Arpad V\|Igaz, Peter\|Tulassay, Zsolt
PMID:	29945573

3372.
Journal:	J Cell Commun Signal. 2018 Jun 11. pii: 10.1007/s12079-018-0471-5.
Title:	Cancer-associated fibroblasts enhance cell proliferation and metastasis of colorectal cancer SW480 cells by provoking long noncoding RNA UCA1.
Author:	Jahangiri, Babak\|Khalaj-Kondori, Mohammad\|Asadollahi, Elahe\|Sadeghizadeh, Majid
PMID:	29948578

3373.
Journal:	Mol Imaging Biol. 2018 Jun 12. pii: 10.1007/s11307-018-1225-8.
Title:	Metabolic Imaging Phenotype Using Radiomics of [(18)F]FDG PET/CT Associated with Genetic Alterations of Colorectal Cancer.
Author:	Chen, Shang-Wen\|Shen, Wei-Chih\|Chen, William Tzu-Liang\|Hsieh, Te-Chun\|Yen, Kuo-Yang\|Chang, Jan-Gowth\|Kao, Chia-Hung
PMID:	29948642

3374.
Journal:	J Mol Diagn. 2018 Sep;20(5):664-676.
Title:	Multicenter Evaluation of the Idylla NRAS-BRAF Mutation Test in Metastatic Colorectal Cancer.
Author:	Prieto-Potin, Ivan\|Montagut, Clara\|Bellosillo, Beatriz\|Evans, Matthew\|Smith, Matthew\|Melchior, Linea\|Reiltin, Werner\|Bennett, Michael\|Pennati, Veronica\|Castiglione, Francesca\|Burrig, Karl-Friedrich\|Cooper, Ulrike\|Dockhorn-Dworniczak, Barbara\|Rossenbach, C
PMID:	29959022

3375.
Journal:	Clin Cancer Res. 2018 Jul 2. pii: 1078-0432.CCR-18-0630.
Title:	Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.
Author:	Hirsch, Daniela\|Wangsa, Darawalee\|Zhu, Yuelin J\|Hu, Yue\|Edelman, Daniel C\|Meltzer, Paul S\|Heselmeyer-Haddad, Kerstin\|Ott, Claudia\|Kienle, Peter\|Galata, Christian\|Horisberger, Karoline\|Ried, Thomas\|Gaiser, Timo
PMID:	29967250

3376.
Journal:	Anticancer Res. 2018 Jul;38(7):4247-4256.
Title:	Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture.
Author:	Luo, Hao\|Nishi, Kensuke\|Ishikura, Shuhei\|Swain, Anthony\|Morishige, Naoyuki\|Yazaki, Ryo\|Ohshima, Takashi\|Shirasawa, Senji\|Tsunoda, Toshiyuki
PMID:	29970558

3377.
Journal:	Anticancer Res. 2018 Jul;38(7):4367-4373.
Title:	Biweekly Administration of TAS-102 for Neutropenia Prevention in Patients with Colorectal Cancer.
Author:	Yoshida, Yoichiro\|Sakamoto, Ryohei\|Kajitani, Ryuji\|Munechika, Taro\|Matsumoto, Yoshiko\|Komono, Akira\|Aisu, Naoya\|Daibo, Kojima\|Kiyomi, Fumihiko\|Hasegawa, Suguru
PMID:	29970575

3378.
Journal:	Arq Bras Cir Dig. 2018;31(2):e1369.
Title:	ANIMAL MODELS FOR COLORECTAL CANCER.
Author:	DE-Souza, Alana Serrano Campelo\|Costa-Casagrande, Thais Andrade
PMID:	29972397

3379.
Journal:	Appl Immunohistochem Mol Morphol. 2018 Jul 5.
Title:	Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.
Author:	Wedden, Sarah\|Miller, Keith\|Frayling, Ian M\|Thomas, Teresa\|Chefani, Alina\|Miller, Karolina\|Hamblin, Angela\|Taylor, Jenny C\|D'Arrigo, Corrado
PMID:	29985199

3380.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2018 Jul 8;47(7):499-504.
Title:	[Feasibility of amplicon-based targeted next-generation sequencing of colorectal cancer in endoscopic biopsies].
Author:	Wang, Y J\|Jiang, R R\|Liu, H J\|Zhang, B\|Ye, F\|Bu, H
PMID:	29996313

3381.
Journal:	PLoS One. 2018 Jul 12;13(7):e0200163.
Title:	Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth.
Author:	Baumer, Nicole\|Rehkamper, Jan\|Appel, Neele\|Terheyden, Lisa\|Hartmann, Wolfgang\|Wardelmann, Eva\|Buchholz, Frank\|Muller-Tidow, Carsten\|Berdel, Wolfgang E\|Baumer, Sebastian
PMID:	30001368

3382.
Journal:	Nat Genet. 2018 Aug;50(8):1189-1195.
Title:	Genome doubling shapes the evolution and prognosis of advanced cancers.
Author:	Bielski, Craig M\|Zehir, Ahmet\|Penson, Alexander V\|Donoghue, Mark T A\|Chatila, Walid\|Armenia, Joshua\|Chang, Matthew T\|Schram, Alison M\|Jonsson, Philip\|Bandlamudi, Chaitanya\|Razavi, Pedram\|Iyer, Gopa\|Robson, Mark E\|Stadler, Zsofia K\|Schultz, Nikolaus\|Baselg
PMID:	30013179

3383.
Journal:	Clin Chem Lab Med. 2018 Jul 17.
Title:	Urinary measurement of circulating tumor DNA for treatment monitoring and prognosis of metastatic colorectal cancer patients.
Author:	Song, Tao\|Mao, Fei\|Shi, Li\|Xu, Xuemei\|Wu, Zirong\|Zhou, Juan\|Xiao, Meifang
PMID:	30016269

3384.
Journal:	Dev Reprod. 2018 Jun;22(2):133-142.
Title:	Combination of BEZ235 and Metformin Has Synergistic Effect on Cell Viability in Colorectal Cancer Cells.
Author:	Kim, Taewan\|Kim, Taehyung\|Choi, Soonyoung\|Ko, Hyeran\|Park, Deokbae\|Lee, Youngki
PMID:	30023463

3385.
Journal:	Gan To Kagaku Ryoho. 2018 May;45(5):875-878.
Title:	[A Case of Postoperative Recurrence of Rectal Cancer in Which Desensitization Therapy Was Effective against Oxaliplatin Allergy in L-OHP].
Author:	Katagiri, Mitsuhiro\|Miwa, Keisuke\|Shimomura, Susumu\|Yomoda, Takatou\|Tajiri, Kensuke\|Nagasu, Sachiko\|Fujino, Shinya\|Koushi, Kenichi\|Fujita, Fumihiko\|Kinugasa, Tetsushi\|Akagi, Yoshito
PMID:	30026456

3386.
Journal:	BMC Cancer. 2018 Jul 20;18(1):752.
Title:	Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.
Author:	Mogensen, M B\|Rossing, M\|Ostrup, O\|Larsen, P N\|Heiberg Engel, P J\|Jorgensen, L N\|Hogdall, E V\|Eriksen, J\|Ibsen, P\|Jess, P\|Grauslund, M\|Nielsen, H J\|Nielsen, F C\|Vainer, B\|Osterlind, K
PMID:	30029640

3387.
Journal:	Acta Oncol. 2018 Jul 23:1-7.
Title:	The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern.
Author:	Prasanna, Thiru\|Karapetis, Christos S\|Roder, David\|Tie, Jeanne\|Padbury, Robert\|Price, Timothy\|Wong, Rachel\|Shapiro, Jeremy\|Nott, Louise\|Lee, Margaret\|Chua, Yu Jo\|Craft, Paul\|Piantadosi, Cynthia\|Sorich, Michael\|Gibbs, Peter\|Yip, Desmond
PMID:	30035653

3388.
Journal:	Cancer Biol Ther. 2018 Jul 23:1-4.
Title:	Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations.
Author:	Ofir Dovrat, Tali\|Sokol, Ethan\|Frampton, Garrett\|Shachar, Eliya\|Pelles, Sharon\|Geva, Ravit\|Wolf, Ido
PMID:	30036146

3389.
Journal:	Am J Pathol. 2018 Oct;188(10):2236-2250.
Title:	Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression.
Author:	Jang, Bo Gun\|Kim, Hye Sung\|Chang, Weon Young\|Bae, Jeong Mo\|Kim, Woo Ho\|Kang, Gyeong Hoon
PMID:	30036518

3390.
Journal:	Mol Cancer. 2018 Jul 23;17(1):102.
Title:	RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.
Author:	Pan, Yi\|Tong, Joanna Hung Man\|Lung, Raymond Wai Ming\|Kang, Wei\|Kwan, Johnny Sheung Him\|Chak, Wing Po\|Tin, Ka Yee\|Chung, Lau Ying\|Wu, Feng\|Ng, Simon Siu Man\|Mak, Tony Wing Chung\|Yu, Jun\|Lo, Kwok Wai\|Chan, Anthony Wing Hung\|To, Ka Fai
PMID:	30037330

3391.
Journal:	Nat Commun. 2018 Jul 23;9(1):2884.
Title:	A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer.
Author:	Saito, Tomoko\|Niida, Atsushi\|Uchi, Ryutaro\|Hirata, Hidenari\|Komatsu, Hisateru\|Sakimura, Shotaro\|Hayashi, Shuto\|Nambara, Sho\|Kuroda, Yosuke\|Ito, Shuhei\|Eguchi, Hidetoshi\|Masuda, Takaaki\|Sugimachi, Keishi\|Tobo, Taro\|Nishida, Haruto\|Daa, Tsutomu\|Chiba, Kenic
PMID:	30038269

3392.
Journal:	Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title:	Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author:	Domingo, Enric\|Camps, Carme\|Kaisaki, Pamela J\|Parsons, Marie J\|Mouradov, Dmitri\|Pentony, Melissa M\|Makino, Seiko\|Palmieri, Michelle\|Ward, Robyn L\|Hawkins, Nicholas J\|Gibbs, Peter\|Askautrud, Hanne\|Oukrif, Dahmane\|Wang, Haitao\|Wood, Joe\|Tomlinson, Evie\|Bark
PMID:	30042065

3393.
Journal:	Oncol Lett. 2018 Nov;16(5):6188-6194.
Title:	EPA significantly improves anti-EGFR targeted therapy by regulating miR-378 expression in colorectal cancer.
Author:	Weng, Wen-Hui\|Leung, Wai-Hung\|Pang, Yeu Jye\|Kuo, Li-Wei\|Hsu, Hsi-Hsien
PMID:	30333883

3394.
Journal:	Med Sci Monit. 2018 Sep 19;24:6608-6616.
Title:	Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/beta-Catenin Signaling Pathway.
Author:	Wu, Yibin\|Chen, Wenjie\|Gong, Lifeng\|Ke, Chongwei\|Wang, Huipeng\|Cai, Yuankun
PMID:	30231258

3395.
Journal:	Cell Rep. 2018 Oct 16;25(3):715-725.e4.
Title:	Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells.
Author:	Hinger, Scott A\|Cha, Diana J\|Franklin, Jeffrey L\|Higginbotham, James N\|Dou, Yongchao\|Ping, Jie\|Shu, Lihua\|Prasad, Nripesh\|Levy, Shawn\|Zhang, Bing\|Liu, Qi\|Weaver, Alissa M\|Coffey, Robert J\|Patton, James G
PMID:	30332650

3396.
Journal:	J Cell Biochem. 2018 Oct 15.
Title:	LncRNA and mRNA signatures associated with neoadjuvant chemoradiotherapy downstaging effects in rectal cancer.
Author:	Li, Ning\|Yu, Jing\|Luo, Aiping\|Tang, Yuan\|Liu, Wenyang\|Wang, Shulian\|Liu, Yueping\|Song, Yongwen\|Fang, Hui\|Chen, Bo\|Qi, Shunan\|Lu, Ningning\|Yu, Zihao\|Li, Yexiong\|Liu, Zhihua\|Jin, Jing
PMID:	30320451

3397.
Journal:	Cancer Med. 2018 Oct 14.
Title:	Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer.
Author:	Shepshelovich, Daniel\|Townsend, Amanda R\|Espin-Garcia, Osvaldo\|Latifovic, Lidija\|O'Callaghan, Chris J\|Jonker, Derek J\|Tu, Dongsheng\|Chen, Eric\|Morgen, Eric\|Price, Timothy J\|Shapiro, Jeremy\|Siu, Lillian L\|Kubo, Michiaki\|Dobrovic, Alexander\|Ratain, Mark J\|X
PMID:	30318772

3398.
Journal:	Br J Cancer. 2018 Oct 15. pii: 10.1038/s41416-018-0232-5.
Title:	The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death.
Author:	Kaliszczak, Maciej\|van Hechanova, Erich\|Li, Yunqing\|Alsadah, Hibah\|Parzych, Katarzyna\|Auner, Holger W\|Aboagye, Eric O
PMID:	30318510

3399.
Journal:	J Clin Pathol. 2018 Oct 12. pii: jclinpath-2018-205412.
Title:	Evaluation of a novel liquid biopsy-based ColoScape assay for mutational analysis of colorectal neoplasia and triage of FIT+ patients: a pilot study.
Author:	Scimia, Mauro\|Du, Jinwei\|Pepe, Francesco\|Bianco, Maria Antonia\|Russo Spena, Silvana\|Patell-Socha, Farah\|Sun, Qing\|Powell, Michael J\|Malapelle, Umberto\|Troncone, Giancarlo
PMID:	30315134

3400.
Journal:	Probiotics Antimicrob Proteins. 2018 Oct 11. pii: 10.1007/s12602-018-9478-8.
Title:	Effects of Lactobacillus acidophilus and Bifidobacterium bifidum Probiotics on the Expression of MicroRNAs 135b, 26b, 18a and 155, and Their Involving Genes in Mice Colon Cancer.
Author:	Heydari, Zahra\|Rahaie, Mahdi\|Alizadeh, Ali Mohammad\|Agah, Shahram\|Khalighfard, Solmaz\|Bahmani, Sahar
PMID:	30311185

3401.
Journal:	Int J Cancer. 2018 Oct 10.
Title:	ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
Author:	Iyer, Prajish\|Shrikhande, Shailesh V\|Ranjan, Malika\|Joshi, Asim\|Gardi, Nilesh\|Prasad, Ratnam\|Dharavath, Bhasker\|Thorat, Rahul\|Salunkhe, Sameer\|Sahoo, Bikram\|Chandrani, Pratik\|Kore, Hitesh\|Mohanty, Bhabani\|Chaudhari, Vikram\|Choughule, Anuradha\|Kawle, Dhana
PMID:	30304546

3402.
Journal:	J Gastrointest Surg. 2018 Oct 1. pii: 10.1007/s11605-018-3978-4.
Title:	The Prognostic Impact of KRAS Mutation in Patients Having Curative Resection of Synchronous Colorectal Liver Metastases.
Author:	Goffredo, Paolo\|Utria, Alan F\|Beck, Anna C\|Chun, Yun Shin\|Howe, James R\|Weigel, Ronald J\|Vauthey, Jean-Nicolas\|Hassan, Imran
PMID:	30276588

3403.
Journal:	Mol Cancer Res. 2018 Oct 1. pii: 1541-7786.MCR-17-0554.
Title:	Efficacy of a Covalent ERK1/2 Inhibitor, CC-90003, in KRAS Mutant Cancer Models Reveals Novel Mechanisms of Response and Resistance.
Author:	Aronchik, Ida\|Dai, Yumin\|Labenski, Matt\|Barnes, Carmen\|Jones, Terri\|QIao, Lixin\|Beebe, Lisa\|Malek, Mehnaz\|Elis, Winfried\|Shi, Tao\|Mavrommatis, Konstantinos\|Bray, Gordon L\|Filvaroff, Ellen H
PMID:	30275173

3404.
Journal:	Cancer Manag Res. 2018 Sep 17;10:3569-3577.
Title:	Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer.
Author:	Mao, Yihao\|Feng, Qingyang\|Zheng, Peng\|Yang, Liangliang\|Liu, Tianyu\|Xu, Yuqiu\|Zhu, Dexiang\|Chang, Wenju\|Ji, Meiling\|Ren, Li\|Wei, Ye\|He, Guodong\|Xu, Jianmin
PMID:	30271205

3405.
Journal:	Eur J Cancer. 2018 Nov;103:205-213.
Title:	Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD databas
Author:	Salem, Mohamed E\|Yin, Jun\|Weinberg, Benjamin A\|Renfro, Lindsay A\|Pederson, Levi D\|Maughan, Timothy S\|Adams, Richard A\|Van Cutsem, Eric\|Falcone, Alfredo\|Tebbutt, Niall C\|Seymour, Matthew T\|Diaz-Rubio, Eduardo\|Aranda, Enrique\|Bokemeyer, Carsten\|Heinemann, V
PMID:	30268921

3406.
Journal:	Int J Cancer. 2018 Sep 25.
Title:	Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.
Author:	Bormann, Felix\|Stinzing, Sebastian\|Tierling, Sascha\|Morkel, Markus\|Rivera Markelova, Maria\|Walter, Jorn\|Weichert, Wilko\|Rossner, Florian\|Kuhn, Natalia\|Perner, Juliane\|Dietz, Johanna\|Ispasanie, Sylvia\|Dietel, Manfred\|Schafer, Reinhold\|Heinemann, Volker\|Ser
PMID:	30252132

3407.
Journal:	Am J Pathol. 2018 Sep 19. pii: S0002-9440(18)30364-X.
Title:	The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.
Author:	Kosumi, Keisuke\|Hamada, Tsuyoshi\|Koh, Hideo\|Borowsky, Jennifer\|Bullman, Susan\|Twombly, Tyler S\|Nevo, Daniel\|Masugi, Yohei\|Liu, Li\|da Silva, Annacarolina\|Chen, Yang\|Du, Chunxia\|Gu, Mancang\|Li, Chenxi\|Li, Wanwan\|Liu, Hongli\|Shi, Yan\|Mima, Kosuke\|Song, Mingy
PMID:	30243655

3408.
Journal:	ESMO Open. 2018 Sep 5;3(6):e000408.
Title:	Somatic cancer genetics in the UK: real-world data from phase I of the Cancer Research UK Stratified Medicine Programme.
Author:	Lindsay, Colin R\|Shaw, Emily C\|Blackhall, Fiona\|Blyth, Kevin G\|Brenton, James D\|Chaturvedi, Anshuman\|Clarke, Noel\|Dick, Craig\|Evans, Thomas R J\|Hall, Geoff\|Hanby, Andrew M\|Harrison, David J\|Johnston, Stephen R D\|Mason, Malcolm D\|Morton, Dion\|Newton-Bishop
PMID:	30233821

3409.
Journal:	BMC Genet. 2018 Sep 19;19(1):85.
Title:	Exome scale map of genetic alterations promoting metastasis in colorectal cancer.
Author:	Goryca, Krzysztof\|Kulecka, Maria\|Paziewska, Agnieszka\|Dabrowska, Michalina\|Grzelak, Marta\|Skrzypczak, Magdalena\|Ginalski, Krzysztof\|Mroz, Andrzej\|Rutkowski, Andrzej\|Paczkowska, Katarzyna\|Mikula, Michal\|Ostrowski, Jerzy
PMID:	30231850

3410.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):231-238.
Title:	Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.
Author:	Dienstmann, Rodrigo\|Salazar, Ramon\|Tabernero, Josep
PMID:	30231342

3411.
Journal:	Am Soc Clin Oncol Educ Book. 2018 May 23;(38):978-997.
Title:	Liquid Biopsy to Identify Actionable Genomic Alterations.
Author:	Ou, Sai-Hong Ignatius\|Nagasaka, Misako\|Zhu, Viola W
PMID:	30231331

3412.
Journal:	Data Brief. 2018 Aug 31;20:1124-1132.
Title:	Data on tumor progression of c-mos deficiency in murine models of Kras(G12D) lung and Apc(Min) colorectal cancer.
Author:	Chen, Zhengxi\|Qiao, Ju\|Wang, Qirui\|Xiao, Qian
PMID:	30229128

3413.
Journal:	Adv Sci (Weinh). 2018 Jul 30;5(10):1800614.
Title:	Simple and Low-Cost Sampling of Cell-Free Nucleic Acids from Blood Plasma for Rapid and Sensitive Detection of Circulating Tumor DNA.
Author:	Jin, Choong Eun\|Koo, Bonhan\|Lee, Tae Yoon\|Han, Kyudong\|Lim, Seok Byung\|Park, In Ja\|Shin, Yong
PMID:	30356899

3414.
Journal:	J Natl Cancer Inst. 2018 Nov 2. pii: 5156228.
Title:	Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.
Author:	Amitay, Efrat L\|Carr, Prudence R\|Jansen, Lina\|Walter, Viola\|Roth, Wilfried\|Herpel, Esther\|Kloor, Matthias\|Blaker, Hendrik\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael
PMID:	30388256

3415.
Journal:	Br J Cancer. 2018 Nov 2. pii: 10.1038/s41416-018-0230-7.
Title:	Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data.
Author:	Trinh, Anne\|Ladrach, Claudia\|Dawson, Heather E\|Ten Hoorn, Sanne\|Kuppen, Peter J K\|Reimers, Marlies S\|Koopman, Miriam\|Punt, Cornelis J A\|Lugli, Alessandro\|Vermeulen, Louis\|Zlobec, Inti
PMID:	30385823

3416.
Journal:	BMC Cancer. 2018 Nov 1;18(1):1056.
Title:	The small organic molecule C19 binds and strengthens the KRAS4b-PDEdelta complex and inhibits growth of colorectal cancer cells in vitro and in vivo.
Author:	Cruz-Nova, Pedro\|Schnoor, Michael\|Correa-Basurto, Jose\|Bello, Martiniano\|Briseno-Diaz, Paola\|Rojo-Dominguez, Arturo\|Ortiz-Mendoza, Carlos M\|Guerrero-Aguirre, Jorge\|Garcia-Vazquez, Francisco J\|Hernandez-Rivas, Rosaura\|Thompson-Bonilla, Maria Del Rocio\|Varg
PMID:	30382908

3417.
Journal:	Pathol Oncol Res. 2018 Oct 30. pii: 10.1007/s12253-018-0520-7.
Title:	Prognostic Value of Progranulin in Patients with Colorectal Cancer Treated with Curative Resection.
Author:	Koo, Dong-Hoe\|Do, In-Gu\|Oh, Sukjoong\|Lee, Yun-Gyoo\|Kim, Kyungeun\|Sohn, Jin Hee\|Park, Soo-Kyung\|Yang, Hyo-Joon\|Jung, Yoon Suk\|Park, Dong Il\|Jeong, Kyung Uk\|Kim, Hyung Ook\|Kim, Hungdai\|Serrero, Ginette\|Chun, Ho-Kyung
PMID:	30378010

3418.
Journal:	J Cell Physiol. 2018 Oct 28.
Title:	Intratumoral infiltrating lymphocytes correlate with improved survival in colorectal cancer patients: Independent of oncogenetic features.
Author:	Nazemalhosseini-Mojarad, Ehsan\|Mohammadpour, Somayeh\|Torshizi Esafahani, Amir\|Gharib, Ehsan\|Larki, Pegah\|Moradi, Afshin\|Amin Porhoseingholi, Mohammad\|Asadzade Aghdaei, Hamid\|Kuppen, Peter J K\|Zali, Mohammad Reza
PMID:	30370522

3419.
Journal:	J Geriatr Oncol. 2018 Oct 23. pii: S1879-4068(18)30032-8.
Title:	Efficacy of panitumumab in older patients with metastatic colorectal cancer: a retrospective analysis using the database of the Hellenic Oncology Research Group (HORG).
Author:	Asimakopoulou, Natalia\|Souglakos, John\|Kentepozidis, Nikolaos\|Karampeazis, Athanasios\|Kotsakis, Athanasios\|Ziras, Nikolaos\|Makrantonakis, Paris\|Prinarakis, Efthimios\|Vamvakas, Lambros\|Georgoulias, Vassilis
PMID:	30366852

3420.
Journal:	J Cell Biochem. 2018 Oct 26.
Title:	Strategies for targeting energy metabolism in Kirsten rat sarcoma viral oncogene homolog -mutant colorectal cancer.
Author:	Wang, Gang\|Wang, Jun-Jie\|Yin, Pei-Hao\|Xu, Ke\|Wang, Yu-Zhu\|Shi, Feng\|Gao, Jing\|Fu, Xing-Li
PMID:	30362665

3421.
Journal:	J Clin Pathol. 2018 Oct 25. pii: jclinpath-2018-205483.
Title:	Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Author:	Susanti, Susanti\|Fadhil, Wakkas\|Murtaza, Shamayal\|Hassall, James C\|Ebili, Henry O\|Oniscu, Anca\|Ilyas, Mohammad
PMID:	30361395

3422.
Journal:	J BUON. 2018 Jul-Aug;23(4):925-935.
Title:	Worst outcomes according to RAS mutation variants: an analysis in patients with metastatic colorectal adenocarcinoma.
Author:	Uson, Pedro L S Jr\|Bugano, Diogo D G\|Moura, Fernando\|Carvalho, Ricardo S\|Maluf, Fernando C
PMID:	30358195

3423.
Journal:	Ther Drug Monit. 2018 Oct 16.
Title:	Circulating cell-free DNA- diagnostic and prognostic applications in personalized cancer therapy.
Author:	Oellerich, M\|Schutz, E\|Beck, J\|Walson, P D
PMID:	30335711

3424.
Journal:	Oncogene. 2018 Oct 23. pii: 10.1038/s41388-018-0554-z.
Title:	Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
Author:	Wagner, Steve\|Vlachogiannis, Georgios\|De Haven Brandon, Alexis\|Valenti, Melanie\|Box, Gary\|Jenkins, Liam\|Mancusi, Caterina\|Self, Annette\|Manodoro, Floriana\|Assiotis, Ioannis\|Robinson, Penny\|Chauhan, Ritika\|Rust, Alistair G\|Matthews, Nik\|Eason, Kate\|Khan, K
PMID:	30353166

3425.
Journal:	Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title:	Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author:	Del Carmen, Sofia\|Sayagues, Jose Maria\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Alcazar, Jose Antonio\|Gervas, Ruth\|Garcia, Jacinto\|Orfao, Alberto\|Bellvis, Luis Munoz\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria
PMID:	30344942

3426.
Journal:	Gastroenterology. 2018 Oct 17. pii: S0016-5085(18)35161-8.
Title:	Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.
Author:	Wang-Bishop, Lihong\|Chen, Zheng\|Gomaa, Ahmed\|Lockhart, Albert Craig\|Salaria, Safia\|Wang, Jialiang\|Lewis, Keeli B\|Ecsedy, Jeffrey\|Washington, Kay\|Beauchamp, Robert Daniel\|El-Rifai, Wael
PMID:	30342037

3427.
Journal:	J Cell Physiol. 2018 Oct 20.
Title:	Strategies to target energy metabolism in consensus molecular subtype 3 along with Kirsten rat sarcoma viral oncogene homolog mutations for colorectal cancer therapy.
Author:	Wang, Gang\|Wang, Jun-Jie\|Yin, Pei-Hao\|Xu, Ke\|Wang, Yu-Zhu\|Shi, Feng\|Gao, Jing\|Fu, Xing-Li
PMID:	30341899

3428.
Journal:	BMC Cancer. 2018 Oct 19;18(1):998.
Title:	Genetic and immunological biomarkers predict metastatic disease recurrence in stage III colon cancer.
Author:	Sperlich, Andreas\|Balmert, Alexander\|Doll, Dietrich\|Bauer, Sabine\|Franke, Fabian\|Keller, Gisela\|Wilhelm, Dirk\|Mur, Anna\|Respondek, Michael\|Friess, Helmut\|Nitsche, Ulrich\|Janssen, Klaus-Peter
PMID:	30340556

3429.
Journal:	Ann Oncol. 2018 Oct 18. pii: 5136414.
Title:	Biomarker analysis beyond angiogenesis: RAS/RAF mutation status, tumour sidedness, and second-line ramucirumab efficacy in patients with metastatic colorectal carcinoma from RAISE, a global phase 3 study.
Author:	Yoshino, T\|Portnoy, D C\|Obermannova, R\|Bodoky, G\|Prausova, J\|Garcia-Carbonero, R\|Ciuleanu, T\|Garcia-Alfonso, P\|Cohn, A L\|Van Cutsem, E\|Yamazaki, K\|Lonardi, S\|Muro, K\|Kim, T W\|Yamaguchi, K\|Grothey, A\|O'Connor, J\|Taieb, J\|Wijayawardana, S R\|Hozak, R R\|Nasro
PMID:	30339194

3430.
Journal:	Lab Chip. 2018 Oct 19.
Title:	Microfluidic-based solid phase extraction of cell free DNA.
Author:	Campos, Camila D M\|Gamage, Sachindra S T\|Jackson, Joshua M\|Witek, Malgorzata A\|Park, Daniel S\|Murphy, Michael C\|Godwin, Andrew K\|Soper, Steven A
PMID:	30339164

3431.
Journal:	Clin Lab. 2018 Oct 1;64(10):1719-1730.
Title:	Early Detection of Colorectal Cancer: a Multi-Center Pre-Clinical Case Cohort Study for Validation of a Combined DNA Stool Test.
Author:	Dollinger, Matthias M\|Behl, Susanna\|Fleig, Wolfgang E
PMID:	30336540

3432.
Journal:	Clin Colorectal Cancer. 2018 Jul 5. pii: S1533-0028(18)30114-2.
Title:	Association of Clinicopathologic and Molecular Markers on Stage-specific Survival of Right Versus Left Colon Cancer.
Author:	Narayanan, Sumana\|Gabriel, Emmanuel\|Attwood, Kristopher\|Boland, Patrick\|Nurkin, Steven
PMID:	30108021

3433.
Journal:	Asian Pac J Cancer Prev. 2018 Aug 24;19(8):2183-2190.
Title:	Main Risk Factors Association with Proto-Oncogene Mutations in Colorectal Cancer
Author:	Dolatkhah, Roya\|Somi, Mohammad Hossein\|Shabanloei, Reza\|Farassati, Faris\|Fakhari, Ali\|Dastgiri, Saeed
PMID:	30139223

3434.
Journal:	Int J Oncol. 2018 Nov;53(5):1869-1880.
Title:	COL1A1: A potential therapeutic target for colorectal cancer expressing wild-type or mutant KRAS.
Author:	Zhang, Zheying\|Fang, Cheng\|Wang, Yongxia\|Zhang, Jinghang\|Yu, Jian\|Zhang, Yongxi\|Wang, Xianwei\|Zhong, Jiateng
PMID:	30132520

3435.
Journal:	Digestion. 2018 Aug 21;98(4):263-269.
Title:	Anti-EGF Receptor-Based Conversion Chemotherapy in RAS Wild-Type Colorectal Cancer Patients: Impact on Survival and Resection Rates.
Author:	Koch, Christine\|Schmidt, Niklas\|Winkelmann, Ria\|Eichler, Katrin\|Pession, Ursula\|Bechstein, Wolf Otto\|Zeuzem, Stefan\|Waidmann, Oliver\|Trojan, Jorg
PMID:	30130797

3436.
Journal:	Cancer Med. 2018 Aug 19.
Title:	Randomized, double-blind, phase two study of ruxolitinib plus regorafenib in patients with relapsed/refractory metastatic colorectal cancer.
Author:	Fogelman, David\|Cubillo, Antonio\|Garcia-Alfonso, Pilar\|Miron, Maria Luisa Limon\|Nemunaitis, John\|Flora, Daniel\|Borg, Christophe\|Mineur, Laurent\|Vieitez, Jose M\|Cohn, Allen\|Saylors, Gene\|Assad, Albert\|Switzky, Julie\|Zhou, Li\|Bendell, Johanna
PMID:	30123970

3437.
Journal:	Int J Cancer. 2018 Aug 19.
Title:	Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer.
Author:	Eilertsen, Ina A\|Sveen, Anita\|Stromme, Jonas M\|Skotheim, Rolf I\|Nesbakken, Arild\|Lothe, Ragnhild A
PMID:	30121958

3438.
Journal:	Hum Pathol. 2018 Aug 16. pii: S0046-8177(18)30312-5.
Title:	Protocadherin gamma A7 is down-regulated in colorectal cancer and associated with the prognosis in patients with wild-type KRAS.
Author:	Liu, Yingdi\|Peng, Kangsheng\|Xie, Ruting\|Zheng, Jiayi\|Guo, Jing\|Wei, Rong\|Yang, Huiqiong\|Cai, Chunmiao\|Wei, Qing
PMID:	30121367

3439.
Journal:	PLoS One. 2018 Aug 17;13(8):e0200836.
Title:	Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.
Author:	Pal, Rekha\|Wei, Ning\|Song, Nan\|Wu, Shaoyu\|Kim, Rim S\|Wang, Ying\|Gavin, Patrick G\|Lucas, Peter C\|Srinivasan, Ashok\|Allegra, Carmen J\|Jacobs, Samuel A\|Paik, Soonmyung\|Schmitz, John C\|Pogue-Geile, Katherine L
PMID:	30118499

3440.
Journal:	Gastroenterology Res. 2018 Aug;11(4):264-273.
Title:	Difference Between Left-Sided and Right-Sided Colorectal Cancer: A Focused Review of Literature.
Author:	Baran, Burcin\|Mert Ozupek, Nazli\|Yerli Tetik, Nihal\|Acar, Emine\|Bekcioglu, Omer\|Baskin, Yasemin
PMID:	30116425

3441.
Journal:	Exp Cell Res. 2018 Aug 13. pii: S0014-4827(18)30701-8.
Title:	Fos-like antigen 2 (FOSL2) promotes metastasis in colon cancer.
Author:	Fei, Bing-Yuan\|Wang, Xiu-Ying\|Fang, Xue-Dong
PMID:	30114390

3442.
Journal:	Contemp Oncol (Pozn). 2018;22(2):75-85.
Title:	Quality and practical aspects of pathological and molecular diagnostics in metastatic colorectal cancer (mCRC).
Author:	Tysarowski, Andrzej\|Nasierowska-Guttmejer, Anna
PMID:	30150883

3443.
Journal:	Oncol Rep. 2018 Oct;40(4):2171-2182.
Title:	Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells.
Author:	Liu, Bi-Sheng\|Xia, Hong-Wei\|Zhou, Sheng\|Liu, Qing\|Tang, Qiu-Lin\|Bi, Na-Xi\|Zhou, Ji-Tao\|Gong, Qi-Yong\|Nie, Yong-Zhan\|Bi, Feng
PMID:	30106444

3444.
Journal:	Biochem J. 2018 Sep 5;475(17):2749-2767.
Title:	Characterizing the interaction between insulin-like growth factor 2 mRNA-binding protein 1 (IMP1) and KRAS expression.
Author:	Mackedenski, Sebastian\|Wang, Chuyi\|Li, Wai-Ming\|Lee, Chow H
PMID:	30104206

3445.
Journal:	Hum Pathol. 2018 Aug 7. pii: S0046-8177(18)30296-X.
Title:	EGFR gene copy number decreases during anti-EGFR antibody therapy in colorectal cancer.
Author:	Birkman, Eva-Maria\|Avoranta, Tuulia\|Algars, Annika\|Korkeila, Eija\|Lintunen, Minnamaija\|Lahtinen, Laura\|Kuopio, Teijo\|Ristamaki, Raija\|Carpen, Olli\|Sundstrom, Jari
PMID:	30096327

3446.
Journal:	Arch Pathol Lab Med. 2018 Aug 8.
Title:	A Highly Verified Assay for KRAS Mutation Detection in Tissue and Plasma of Lung, Colorectal, and Pancreatic Cancer.
Author:	Li, Jing\|Gan, Stephanie\|Blair, Alan\|Min, Kyungji\|Rehage, Taraneh\|Hoeppner, Corey\|Halait, Harkanwal\|Brophy, Victoria H
PMID:	30088781

3447.
Journal:	Mol Biol Rep. 2018 Oct;45(5):1339-1348.
Title:	A natural flavonoid lawsonaringenin induces cell cycle arrest and apoptosis in HT-29 colorectal cancer cells by targeting multiple signalling pathways.
Author:	Anwar, Areeba\|Uddin, Nizam\|Siddiqui, Bina Shaheen\|Siddiqui, Rafat Ali\|Begum, Sabira\|Choudhary, Muhammad Iqbal
PMID:	30088202

3448.
Journal:	J Biol Chem. 2018 Sep 21;293(38):14891-14904.
Title:	Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation.
Author:	Boyle, Kathleen A\|Van Wickle, Jonathan\|Hill, R Blake\|Marchese, Adriano\|Kalyanaraman, Balaraman\|Dwinell, Michael B
PMID:	30087121

3449.
Journal:	Adv Clin Exp Med. 2018 Aug 7.
Title:	Analysis of KRAS, NRAS, BRAF, and PIK3CA mutations could predict metastases in colorectal cancer: A preliminary study.
Author:	Wojas-Krawczyk, Kamila\|Kalinka-Warzocha, Ewa\|Reszka, Katarzyna\|Nicos, Marcin\|Szumilo, Justyna\|Mandziuk, Slawomir\|Szczepaniak, Katarzyna\|Kupnicka, Dorota\|Lewandowski, Remigiusz\|Milanowski, Janusz\|Krawczyk, Pawel
PMID:	30085422

3450.
Journal:	Microrna. 2018 Aug 2. pii: MIRNA-EPUB-92141.
Title:	Computational Analysis of miRNA and their Gene Targets Significantly Involved in Colorectal Cancer Progression.
Author:	Kandhavelu, Jeyalakshmi\|Subramanian, Kumar\|Khan, Amber\|Omar, Aadilah\|Ruff, Paul\|Penny, Clement
PMID:	30073936

3451.
Journal:	Transl Oncol. 2018 Oct;11(5):1188-1201.
Title:	Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis.
Author:	Advani, Shailesh M\|Advani, Pragati\|DeSantis, Stacia M\|Brown, Derek\|VonVille, Helena M\|Lam, Michael\|Loree, Jonathan M\|Mehrvarz Sarshekeh, Amir\|Bressler, Jan\|Lopez, David S\|Daniel, Carrie R\|Swartz, Michael D\|Kopetz, Scott
PMID:	30071442

3452.
Journal:	J Cancer Res Clin Oncol. 2018 Sep 10. pii: 10.1007/s00432-018-2744-z.
Title:	Variability in HER2 expression between primary colorectal cancer and corresponding metastases.
Author:	Shan, Lina\|Lv, Yiming\|Bai, Bingjun\|Huang, Xuefeng\|Zhu, Hongbo
PMID:	30203148

3453.
Journal:	Cancer Immunol Res. 2018 Sep 18. pii: 2326-6066.CIR-18-0174.
Title:	Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status.
Author:	Hamada, Tsuyoshi\|Zhang, Xuehong\|Mima, Kosuke\|Bullman, Susan\|Sukawa, Yasutaka\|Nowak, Jonathan A\|Kosumi, Keisuke\|Masugi, Yohei\|Twombly, Tyler S\|Cao, Yin\|Song, Mingyang\|Liu, Li\|da Silva, Annacarolina\|Shi, Yan\|Gu, Mancang\|Li, Wanwan\|Koh, Hideo\|Nosho, Katsuhik
PMID:	30228205

3454.
Journal:	Oncol Rep. 2018 Nov;40(5):2690-2697.
Title:	EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFRpositive cancer cells.
Author:	Hashimi, Saeed M\|Grant, Brock\|Alqurashi, Naif\|Alowaidi, Faisal\|Wei, Ming Q
PMID:	30226622

3455.
Journal:	Oncotarget. 2018 Aug 24;9(66):32653-32666.
Title:	The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis.
Author:	Takane, Kiyoko\|Fukuyo, Masaki\|Matsusaka, Keisuke\|Ota, Satoshi\|Rahmutulla, Bahityar\|Matsushita, Kazuyuki\|Miyauchi, Hideaki\|Nakatani, Yukio\|Matsubara, Hisahiro\|Kaneda, Atsushi
PMID:	30220972

3456.
Journal:	Eur J Cancer. 2018 Sep 12;103:98-107.
Title:	Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour.
Author:	Hamada, Tsuyoshi\|Liu, Li\|Nowak, Jonathan A\|Mima, Kosuke\|Cao, Yin\|Ng, Kimmie\|Twombly, Tyler S\|Song, Mingyang\|Jung, Seungyoun\|Dou, Ruoxu\|Masugi, Yohei\|Kosumi, Keisuke\|Shi, Yan\|da Silva, Annacarolina\|Gu, Mancang\|Li, Wanwan\|Keum, NaNa\|Wu, Kana\|Nosho, Katsuhik
PMID:	30219720

3457.
Journal:	Surg Oncol. 2018 Sep;27(3):485-489.
Title:	Kras-mutation influences outcomes for palliative primary tumor resection in advanced colorectal cancer-a Turkish Oncology Group study.
Author:	Korkmaz, Levent\|Coskun, Hasan Senol\|Dane, Faysal\|Karabulut, Bulent\|Karaagac, Mustafa\|Cabuk, Devrim\|Karabulut, Senem\|Aykan, Nuri Faruk\|Doruk, Hatice\|Avci, Nilufer\|Turhal, Nazim Serdar\|Artac, Mehmet
PMID:	30217306

3458.
Journal:	Int J Mol Sci. 2018 Sep 13;19(9). pii: ijms19092752.
Title:	Ascorbic Acid in Colon Cancer: From the Basic to the Clinical Applications.
Author:	El Halabi, Ibrahim\|Bejjany, Rachelle\|Nasr, Rihab\|Mukherji, Deborah\|Temraz, Sally\|Nassar, Farah J\|El Darsa, Haidar\|Shamseddine, Ali
PMID:	30217071

3459.
Journal:	Cancer Manag Res. 2018 Aug 28;10:2915-2924.
Title:	Efficacy and safety of TAS-102 in refractory metastatic colorectal cancer: a meta-analysis.
Author:	Chen, Duke\|Wu, Yu-Shen\|Lin, Huapeng\|Wang, Yihan\|Li, Longhao\|Zhang, Tao
PMID:	30214286

3460.
Journal:	Clin Colorectal Cancer. 2018 Jul 17. pii: S1533-0028(18)30133-6.
Title:	Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Author:	Khan, Maliha\|Loree, Jonathan M\|Advani, Shailesh M\|Ning, Jing\|Li, Wen\|Pereira, Allan A L\|Lam, Michael\|Raghav, Kanwal\|Morris, Van K\|Broaddus, Russell\|Maru, Dipen\|Overman, Michael J\|Kopetz, Scott
PMID:	30205948

3461.
Journal:	Cell Biol Int. 2018 Sep 11.
Title:	Quercetin preferentially induces apoptosis in KRAS-mutant colorectal cancer cells via JNK signaling pathways.
Author:	Yang, Yiwen\|Wang, Tao\|Chen, Degao\|Ma, Qizhao\|Zheng, Yanjiang\|Liao, Shiping\|Wang, Yufang\|Zhang, Ji
PMID:	30203888

3462.
Journal:	Virchows Arch. 2018 Oct;473(4):413-423.
Title:	HER2 status in patients with residual rectal cancer after preoperative chemoradiotherapy: the relationship with molecular results and clinicopathologic features.
Author:	Park, Jun Seok\|Yoon, Ghilsuk\|Kim, Hye Jin\|Park, Soo Yeun\|Choi, Gyu Seog\|Kang, Min Kyu\|Kim, Jong Gwang\|Jang, Jung-Sik\|Seo, An Na
PMID:	30056472

3463.
Journal:	Cancer Cell Int. 2018 Sep 6;18:131.
Title:	Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases.
Author:	Fassan, Matteo\|Vianello, Luca\|Sacchi, Diana\|Fanelli, Giuseppe N\|Munari, Giada\|Scarpa, Marco\|Cappellesso, Rocco\|Loupakis, Fotios\|Lanza, Cristiano\|Salmaso, Roberta\|Mescoli, Claudia\|Valeri, Nicola\|Agostini, Marco\|D'Angelo, Edoardo\|Lonardi, Sara\|Pucciarelli,
PMID:	30202242

3464.
Journal:	Crit Rev Oncol Hematol. 2018 Oct;130:78-91.
Title:	Clinical update on K-Ras targeted therapy in gastrointestinal cancers.
Author:	Pant, Shubham\|Hubbard, Joleen\|Martinelli, Erika\|Bekaii-Saab, Tanios
PMID:	30196915

3465.
Journal:	Int J Colorectal Dis. 2018 Sep 8. pii: 10.1007/s00384-018-3158-8.
Title:	First-line therapies in metastatic colorectal cancer: integrating clinical benefit with the costs of drugs.
Author:	Giuliani, Jacopo\|Bonetti, Andrea
PMID:	30196427

3466.
Journal:	Int J Cancer. 2018 Sep 8.
Title:	PDEdelta inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas.
Author:	Klein, Christian H\|Truxius, Dina C\|Vogel, Holger A\|Harizanova, Jana\|Murarka, Sandip\|Martin-Gago, Pablo\|Bastiaens, Philippe I H
PMID:	30194764

3467.
Journal:	PLoS One. 2018 Sep 6;13(9):e0203051.
Title:	Colorectal cancer molecular classification using BRAF, KRAS, microsatellite instability and CIMP status: Prognostic implications and response to chemotherapy.
Author:	Murcia, Oscar\|Juarez, Miriam\|Rodriguez-Soler, Maria\|Hernandez-Illan, Eva\|Giner-Calabuig, Mar\|Alustiza, Miren\|Egoavil, Cecilia\|Castillejo, Adela\|Alenda, Cristina\|Barbera, Victor\|Mangas-Sanjuan, Carolina\|Yuste, Ana\|Bujanda, Luis\|Clofent, Joan\|Andreu, Montse
PMID:	30188916

3468.
Journal:	Biomed Res Int. 2018 Aug 13;2018:3724393.
Title:	Histogram Analysis of Perfusion Parameters from Dynamic Contrast-Enhanced MR Imaging with Tumor Characteristics and Therapeutic Response in Locally Advanced Rectal Cancer.
Author:	Yeo, Dong Myung\|Oh, Soon Nam\|Choi, Moon Hyung\|Lee, Sung Hak\|Lee, Myung Ah\|Jung, Seung Eun
PMID:	30186857

3469.
Journal:	Adv Exp Med Biol. 2018;1072:165-169.
Title:	Multispectral Near-Infrared Optical Tomography for Cancer Hypoxia Study in Mice.
Author:	Kalyanov, A\|Germanier, C\|Ahnen, L\|Jiang, J\|Lindner, S\|Di Costanzo Mata, A\|Sanchez Majos, S\|Rudin, M\|Wolf, M
PMID:	30178340

3470.
Journal:	J Cancer Res Clin Oncol. 2018 Aug 31. pii: 10.1007/s00432-018-2742-1.
Title:	The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing.
Author:	Zou, Shuang-Mei\|Li, Wei-Hua\|Wang, Wen-Miao\|Li, Wen-Bin\|Shi, Su-Sheng\|Ying, Jian-Ming\|Lyu, Ning
PMID:	30171333

3471.
Journal:	Cell Death Dis. 2018 Aug 29;9(9):877.
Title:	Novel beta-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer.
Author:	Kim, Su Jin\|Noh, Tae Hwan\|Son, Sujin\|Kim, Do Hyun\|Kim, Wooseong\|Lee, Yunna\|Choo, Jieun\|Heo, Gwangbeom\|Kim, Min Jae\|Chung, Hae Young\|Jung, Yunjin\|Jung, Jee Hyung\|Moon, Hyung Ryong\|Im, Eunok
PMID:	30158525