Primary Site >> Biliary tract Cancer

Gene >> KRAS

1.
Journal: Nihon Shokakibyo Gakkai Zasshi. 1990 Mar;87(3):811-5.
Title: [Detection of ras gene mutations of primary hepatic malignant tumors by polymerase chain reaction and direct sequencing method].
Author: Tada, M|Omata, M|Ohto, M
PMID: 2167400
2.
Journal: Int J Pancreatol. 1993 Oct;14(2):135-43.
Title: The point mutation of c-Ki-ras at codon 12 in carcinoma of the pancreatic head region and in intraductal mucin-hypersecreting neoplasm of the pancreas.
Author: Satoh, K|Sawai, T|Shimosegawa, T|Koizumi, M|Yamazaki, T|Mochizuki, F|Toyota, T
PMID: 8283077
3.
Journal: Am J Pathol. 1993 Apr;142(4):1163-72.
Title: Neoplasia of the ampulla of Vater. Ki-ras and p53 mutations.
Author: Scarpa, A|Capelli, P|Zamboni, G|Oda, T|Mukai, K|Bonetti, F|Martignoni, G|Iacono, C|Serio, G|Hirohashi, S
PMID: 8475992
4.
Journal: Nihon Shokakibyo Gakkai Zasshi. 1993 Apr;90(4):789-94.
Title: [Detection of point mutation of K-ras gene codon 12 in biliary tract and ampullary carcinoma by modified two-step polymerase chain reaction].
Author: Watanabe, M|Tanaka, J|Masauji, N|Matsuura, A|Kiyama, Y|Morii, K|Naohara, T|Saitoh, M|Higa, T|Kasai, M
PMID: 8492470
5.
Journal: Jpn J Clin Oncol. 1994 Dec;24(6):305-10.
Title: High rates of Ki-ras point mutation in both intra- and extra-hepatic cholangiocarcinomas.
Author: Ohashi, K|Tsutsumi, M|Nakajima, Y|Noguchi, O|Okita, S|Kitada, H|Tsujiuchi, T|Kobayashi, E|Nakano, H|Konishi, Y
PMID: 7830335
6.
Journal: Gastroenterology. 1994 Oct;107(4):1147-53.
Title: Point mutation of K-ras gene codon 12 in biliary tract tumors.
Author: Watanabe, M|Asaka, M|Tanaka, J|Kurosawa, M|Kasai, M|Miyazaki, T
PMID: 7926462
7.
Journal: Int J Cancer. 1994 Oct 1;59(1):39-42.
Title: ras-family gene mutations in neoplasia of the ampulla of Vater.
Author: Scarpa, A|Zamboni, G|Achille, A|Capelli, P|Bogina, G|Iacono, C|Serio, G|Accolla, R S
PMID: 7927901
8.
Journal: Cancer Res. 1994 Jul 1;54(13):3568-73.
Title: Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia.
Author: Caldas, C|Hahn, S A|Hruban, R H|Redston, M S|Yeo, C J|Kern, S E
PMID: 8012983
9.
Journal: Br J Cancer. 1994 Aug;70(2):278-84.
Title: Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions.
Author: Trumper, L H|Burger, B|von Bonin, F|Hintze, A|von Blohn, G|Pfreundschuh, M|Daus, H
PMID: 8054276
10.
Journal: Gastroenterology. 1995 Nov;109(5):1612-7.
Title: Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology.
Author: Ohashi, K|Nakajima, Y|Kanehiro, H|Tsutsumi, M|Taki, J|Aomatsu, Y|Yoshimura, A|Ko, S|Kin, T|Yagura, K
PMID: 7557145
11.
Journal: Cancer Res. 1995 Jul 1;55(13):2756-60.
Title: Mutations of p16Ink4/CDKN2 and p15Ink4B/MTS2 genes in biliary tract cancers.
Author: Yoshida, S|Todoroki, T|Ichikawa, Y|Hanai, S|Suzuki, H|Hori, M|Fukao, K|Miwa, M|Uchida, K
PMID: 7796400
12.
Journal: J Formos Med Assoc. 1995 Dec;94(12):719-23.
Title: Analysis of K-ras gene mutations in periampullary cancers, gallbladder cancers and cholangiocarcinomas from paraffin-embedded tissue sections.
Author: Lee, J C|Lin, P W|Lin, Y J|Lai, J|Yang, H B|Lai, M D
PMID: 8541732
13.
Journal: Int J Pancreatol. 1995 Dec;18(3):215-20.
Title: Detection of point mutations in K-ras gene at codon 12 in bile from percutaneous transhepatic choledochal drainage tubes for diagnosis of biliary strictures.
Author: Ajiki, T|Onoyama, H|Yamamoto, M|Fujimori, T|Maeda, S|Saitoh, Y
PMID: 8708392
14.
Journal: Clin Mol Pathol. 1995 Dec;48(6):M316-8.
Title: Detection of c-Ki-ras mutations in bile samples from patients with pancreatic and biliary cancers.
Author: O'mahony, S|Longfellow, M|McMahon, M J|Axon, A T|Quirke, P
PMID: 16696030
15.
Journal: Cancer. 1996 Apr 15;77(8 Suppl):1752-7.
Title: K-ras point mutations in cancerous and noncancerous biliary epithelium in patients with pancreaticobiliary maljunction.
Author: Matsubara, T|Sakurai, Y|Sasayama, Y|Hori, H|Ochiai, M|Funabiki, T|Matsumoto, K|Hirono, I
PMID: 8608574
16.
Journal: Am J Gastroenterol. 1996 Jun;91(6):1211-4.
Title: Point mutations of the c-Ki-ras gene in carcinoma and atypical epithelium associated with congenital biliary dilation.
Author: Tomono, H|Nimura, Y|Aono, K|Nakashima, I|Iwamoto, T|Nakashima, N
PMID: 8651173
17.
Journal: J Clin Pathol. 1996 Jun;49(6):460-4.
Title: Clinical significance of K-ras oncogene activation in ampullary neoplasms.
Author: Chung, C H|Wilentz, R E|Polak, M M|Ramsoekh, T B|Noorduyn, L A|Gouma, D J|Huibregtse, K|Offerhaus, G J|Slebos, R J
PMID: 8763258
18.
Journal: Pathol Res Pract. 1996 Jun;192(6):532-40.
Title: Detection of ras oncogene point mutations and simultaneous proliferative fraction estimation in gallbladder cancer.
Author: Saetta, A|Lazaris, A C|Davaris, P S
PMID: 8857639
19.
Journal: J Surg Oncol. 1997 Oct;66(2):97-103.
Title: K-ras gene mutations in intrahepatic bile duct tumors of Syrian golden hamsters.
Author: Yamanaka, S|Tomioka, T|Tajima, Y|Okada, K|Shiku, H|Kanematsu, T
PMID: 9354164
20.
Journal: Oncol Rep. 1997 Nov-Dec;4(6):1373-81.
Title: Analysis of K-ras gene mutations in human pancreatic cancer cell lines and in bile samples from patients with pancreatic and biliary cancers.
Author: Evans, T|Faircloth, M|Deery, A|Thomas, V|Turner, A|Dalgleish, A
PMID: 21590256
21.
Journal: Int J Oncol. 1998 May;12(5):1019-23.
Title: Usefulness of K-ras gene mutation at codon 12 in bile for diagnosing biliary strictures.
Author: Ito, R|Tamura, K|Ashida, H|Nishiwaki, M|Nishioka, A|Yamamoto, Y|Furuyama, J I|Utsunomiya, J
PMID: 9538122
22.
Journal: J Med Assoc Thai. 1998 May;81(5):316-23.
Title: The incidence of K-ras codon 12 mutations in cholangiocarcinoma detected by polymerase chain reaction technique.
Author: Wattanasirichaigoon, S|Tasanakhajorn, U|Jesadapatarakul, S
PMID: 9623030
23.
Journal: Gastrointest Endosc. 1998 Jun;47(6):479-85.
Title: Relative contribution of Ki-ras gene analysis and brush cytology during ERCP for the diagnosis of biliary and pancreatic diseases.
Author: Van Laethem, J L|Bourgeois, V|Parma, J|Delhaye, M|Cochaux, P|Velu, T|Deviere, J|Cremer, M
PMID: 9647372
24.
Journal: Southeast Asian J Trop Med Public Health. 1998 Mar;29(1):71-5.
Title: K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients.
Author: Petmitr, S|Pinlaor, S|Thousungnoen, A|Karalak, A|Migasena, P
PMID: 9740272
25.
Journal: Eur J Gastroenterol Hepatol. 1998 Dec;10(12):1025-9.
Title: Analysis of K-ras gene mutations in rare pancreatic and ampullary tumours.
Author: Ebert, M P|Hoffmann, J|Schneider-Stock, R|Kasper, H U|Schulz, H U|Lippert, H|Roessner, A|Malfertheiner, P
PMID: 9895049
26.
Journal: Jpn J Cancer Res. 1999 Feb;90(2):240-8.
Title: K-ras point mutations in the supernatants of pancreatic juice and bile are reliable for diagnosis of pancreas and biliary tract carcinomas complementary to cytologic examination.
Author: Yamashita, K|Kida, Y|Shinoda, H|Kida, M|Okayasu, I
PMID: 10189896
27.
Journal: Lab Invest. 1999 Apr;79(4):477-83.
Title: Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma.
Author: Kang, Y K|Kim, W H|Lee, H W|Lee, H K|Kim, Y I
PMID: 10212000
28.
Journal: Am J Gastroenterol. 1999 Jun;94(6):1638-42.
Title: Gene mutations of K-ras in gallbladder mucosae and gallbladder carcinoma with an anomalous junction of the pancreaticobiliary duct.
Author: Hanada, K|Tsuchida, A|Iwao, T|Eguchi, N|Sasaki, T|Morinaka, K|Matsubara, K|Kawasaki, Y|Yamamoto, S|Kajiyama, G
PMID: 10364037
29.
Journal: Ann Oncol. 1999;10 Suppl 4:129-30.
Title: Gallbladder carcinoma.
Author: Levin, B
PMID: 10436804
30.
Journal: J Cancer Res Clin Oncol. 1999 Aug-Sep;125(8-9):439-43.
Title: Losses of heterozygosity on chromosomes 17p and 9p/18q may play important roles in early and advanced phases of gallbladder carcinogenesis.
Author: Hidaka, E|Yanagisawa, A|Sakai, Y|Seki, M|Kitagawa, T|Setoguchi, T|Kato, Y
PMID: 10480335
31.
Journal: J Hepatobiliary Pancreat Surg. 1999;6(3):237-44.
Title: Genetic abnormalities involved in the pathogenesis of gallbladder carcinoma.
Author: Wistuba, I I|Albores-Saavedra, J
PMID: 10526058
32.
Journal: Radiat Res. 1999 Dec;152(6 Suppl):S118-24.
Title: Analysis of genetic changes in intrahepatic cholangiocarcinoma induced by thorotrast.
Author: Kamikawa, T|Amenomori, M|Itoh, T|Momoi, H|Hiai, H|Machinami, R|Ishikawa, Y|Mori, T|Shimahara, Y|Yamaoka, Y|Fukumoto, M
PMID: 10564951
33.
Journal: Hepatogastroenterology. 2000 Jan-Feb;47(31):57-70.
Title: Chronic inflammatory bowel disease and cancer.
Author: Pohl, C|Hombach, A|Kruis, W
PMID: 10690586
34.
Journal: J Hepatobiliary Pancreat Surg. 2000;7(2):198-205.
Title: Relation between K-ras codon 12 mutation and p53 protein overexpression in gallbladder cancer and biliary ductal epithelia in patients with pancreaticobiliary maljunction.
Author: Masuhara, S|Kasuya, K|Aoki, T|Yoshimatsu, A|Tsuchida, A|Koyanagi, Y
PMID: 10982614
35.
Journal: J Surg Oncol. 2000 Dec;75(4):246-51.
Title: K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder.
Author: Kim, S W|Her, K H|Jang, J Y|Kim, W H|Kim, Y T|Park, Y H
PMID: 11135265
36.
Journal: J Hepatobiliary Pancreat Surg. 2000;7(4):426-31.
Title: p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.
Author: Ahrendt, S A|Rashid, A|Chow, J T|Eisenberger, C F|Pitt, H A|Sidransky, D
PMID: 11180865
37.
Journal: Cancer Lett. 2001 May 26;166(2):135-41.
Title: Allelotype analysis of gallbladder carcinoma associated with anomalous junction of pancreaticobiliary duct.
Author: Nakayama, K|Konno, M|Kanzaki, A|Morikawa, T|Miyashita, H|Fujioka, T|Uchida, T|Miyazaki, K|Takao, S|Aikou, T|Fukumoto, M|Takebayashi, Y
PMID: 11311485
38.
Journal: Cancer Lett. 2001 Aug 10;169(1):59-68.
Title: Genetic alterations in gallbladder adenoma, dysplasia and carcinoma.
Author: Kim, Y T|Kim, J|Jang, Y H|Lee, W J|Ryu, J K|Park, Y K|Kim, S W|Kim, W H|Yoon, Y B|Kim, C Y
PMID: 11410326
39.
Journal: World J Surg. 2002 Jan;26(1):91-8.
Title: Clinical and genetic analysis of noncancerous and cancerous biliary epithelium in patients with pancreaticobiliary maljunction.
Author: Nagai, Moritaka|Watanabe, Masatoshi|Iwase, Teruhiko|Yamao, Kenji|Isaji, Shuji
PMID: 11898040
40.
Journal: Hepatogastroenterology. 2002 May-Jun;49(45):604-8.
Title: Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma.
Author: Isa, Tsutomu|Tomita, Shuji|Nakachi, Atsushi|Miyazato, Hiroshi|Shimoji, Hideaki|Kusano, Toshiomi|Muto, Yoshihiro|Furukawa, Masato
PMID: 12063950
41.
Journal: Clin Cancer Res. 2002 Oct;8(10):3156-63.
Title: K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in China.
Author: Rashid, Asif|Ueki, Takashi|Gao, Yu-Tang|Houlihan, Patrick Scott|Wallace, Charita|Wang, Bing-Sheng|Shen, Ming-Chang|Deng, Jie|Hsing, Ann W
PMID: 12374683
42.
Journal: Surg Today. 2002;32(11):1019-22.
Title: Biliary papillomatosis arising in a congenital choledochal cyst: report of a case.
Author: Iwasaki, Yoshimi|Shimoda, Mitsugi|Furihata, Tadashi|Rokkaku, Kyu|Sakuma, Atsushi|Ichikawa, Kazuhito|Fujimori, Takahiro|Kubota, Keiichi
PMID: 12444445
43.
Journal: Int J Mol Med. 2003 Jan;11(1):65-9.
Title: Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma.
Author: Kohya, Naohiko|Kitajima, Yoshihiko|Kitahara, Kenji|Miyazaki, Kohji
PMID: 12469220
44.
Journal: Mod Pathol. 2003 Mar;16(3):272-8.
Title: Role of the DPC4 tumor suppressor gene in adenocarcinoma of the ampulla of Vater: analysis of 140 cases.
Author: McCarthy, Denis M|Hruban, Ralph H|Argani, Pedram|Howe, James R|Conlon, Kevin C|Brennan, Murray F|Zahurak, Marianna|Wilentz, Robb E|Cameron, John L|Yeo, Charles J|Kern, Scott E|Klimstra, David S
PMID: 12640108
45.
Journal: Gut. 2003 May;52(5):706-12.
Title: Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma.
Author: Tannapfel, A|Sommerer, F|Benicke, M|Katalinic, A|Uhlmann, D|Witzigmann, H|Hauss, J|Wittekind, C
PMID: 12692057
46.
Journal: Mod Pathol. 2003 Apr;16(4):299-308.
Title: Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions.
Author: Parwani, Anil V|Geradts, Joseph|Caspers, Eric|Offerhaus, G Johan|Yeo, Charles J|Cameron, John L|Klimstra, David S|Maitra, Anirban|Hruban, Ralph H|Argani, Pedram
PMID: 12692194
47.
Journal: J Pediatr Surg. 2003 May;38(5):694-7.
Title: DPC-4 (Smad-4) and K-ras gene mutations in biliary tract epithelium in children with anomalous pancreaticobiliary ductal union.
Author: Shimotake, Takashi|Aoi, Shigeyoshi|Tomiyama, Hideki|Iwai, Naomi
PMID: 12720172
48.
Journal: Hum Pathol. 2003 Sep;34(9):902-10.
Title: Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract.
Author: Abraham, Susan C|Lee, Jae-Hyuk|Hruban, Ralph H|Argani, Pedram|Furth, Emma E|Wu, Tsung-Teh
PMID: 14562286
49.
Journal: J Gastroenterol Hepatol. 2004 Aug;19(8):916-21.
Title: Mutational spectrum of K-ras oncogene among Indian patients with gallbladder cancer.
Author: Singh, Mahendra Kumar|Chetri, Kamal|Pandey, Udai Bhan|Kapoor, Vinay Kumar|Mittal, Balraj|Choudhuri, Gourdas
PMID: 15242496
50.
Journal: Rev Med Chil. 2004 Aug;132(8):955-60.
Title: [K-ras gene mutation in gallbladder carcinoma].
Author: Roa, Juan Carlos|Roa, Ivan|de Aretxabala, Xabier|Melo, Angelica|Faria, Gaspar|Tapia, Oscar
PMID: 15478297
51.
Journal: Int J Mol Med. 2005 Mar;15(3):425-30.
Title: Histologic and genetic analysis of the gallbladder in patients with occult pancreatobiliary reflux.
Author: Itoi, Takao|Tsuchida, Akihiko|Itokawa, Fumihide|Sofuni, Atsushi|Kurihara, Toshio|Tsuchiya, Takayoshi|Moriyasu, Fuminori|Kasuya, Kazuhiko|Serizawa, Hiromi
PMID: 15702232
52.
Journal: Rev Med Chil. 2005 Dec;133(12):1434-40. Epub 2006 Jan 27.
Title: [Frequency of K-ras mutation in biliary and pancreatic tumors].
Author: Roa, Juan Carlos|Anabalon, Leonardo|Tapia, Oscar|Melo, Angelica|de Aretxabala, Xabier|Roa, Ivan
PMID: 16446870
53.
Journal: J Surg Oncol. 2006 Jun 15;93(8):644-9.
Title: K-ras, p53 mutations, and microsatellite instability (MSI) in gallbladder cancer.
Author: Saetta, Angelica A
PMID: 16724348
54.
Journal: Jpn J Clin Oncol. 2006 Oct;36(10):638-42.
Title: Double cancer of gall bladder and bile duct not associated with anomalous junction of the pancreaticobiliary duct system.
Author: Hori, Hiiroshige|Ajiki, Tetsuo|Fujita, Tsunenori|Okazaki, Taro|Suzuki, Yasuyuki|Kuroda, Yoshikazu|Fujimori, Takahiro
PMID: 16908513
55.
Journal: J Cancer Res Clin Oncol. 2007 Apr;133(4):271-8. Epub 2006 Nov 25.
Title: Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells.
Author: Jinawath, Artit|Akiyama, Yoshimitsu|Sripa, Banchob|Yuasa, Yasuhito
PMID: 17294242
56.
Journal: J Gastrointest Surg. 2007 May;11(5):671-81.
Title: Diagnosis and surgical management of gallbladder cancer: a review.
Author: Reid, Kaye M|Ramos-De la Medina, Antonio|Donohue, John H
PMID: 17468929
57.
Journal: Asian Pac J Cancer Prev. 2008 Jan-Mar;9(1):101-6.
Title: Mutations of KRAS and TP53 in a minor proportion of Opisthorchis viverrini-associated cholangiocarcinomas in a hamster model.
Author: Tangkawattana, Sirikachorn|Kaewkes, Sasithorn|Pairojkul, Chawalit|Tangkawattana, Prasarn|Sripa, Banchob
PMID: 18439086
58.
Journal: J Gastrointest Surg. 2008 Oct;12(10):1664-72; discussion 1672-3.
Title: Loss of heterozygosity predicts poor survival after resection of pancreatic adenocarcinoma.
Author: Franko, Jan|Krasinskas, Alyssa M|Nikiforova, Marina N|Zarnescu, Narcis O|Lee, Kenneth K W|Hughes, Steven J|Bartlett, David L|Zeh, Herbert J 3rd|Moser, A James
PMID: 18677542
59.
Journal: Expert Opin Med Diagn. 2008 May;2(5):511-26.
Title: Biomarkers in carcinoma of the gallbladder.
Author: Rupesh, Priya|Manoj, Pandey|Vijay Kumar, Shukla
PMID: 23495740
60.
Journal: J Hepatobiliary Pancreat Surg. 2009;16(3):376-81.
Title: p53 gene mutation and p53 protein overexpression in a patient with simultaneous double cancer of the gallbladder and bile duct associated with pancreaticobiliary maljunction.
Author: Kasuya, Kazuhiko|Nagakawa, Yuichi|Matsudo, Takaaki|Ozawa, Takashi|Tsuchida, Akihiko|Aoki, Tatsuya|Itoi, Takao|Itokawa, Fumihide
PMID: 19183832
61.
Journal: Br J Cancer. 2009 Apr 21;100(8):1257-66.
Title: Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma.
Author: Yoshikawa, D|Ojima, H|Kokubu, A|Ochiya, T|Kasai, S|Hirohashi, S|Shibata, T
PMID: 19319137
62.
Journal: J Gastrointest Surg. 2009 Aug;13(8):1510-6.
Title: Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas.
Author: Schonleben, Frank|Qiu, Wanglong|Allendorf, John D|Chabot, John A|Remotti, Helen E|Su, Gloria H
PMID: 19440799
63.
Journal: J Mol Diagn. 2009 Nov;11(6):583-9.
Title: Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology.
Author: Shi, Chanjuan|Chandrasekaran, Arjun|Thuluvath, Paul J|Karikari, Collins|Argani, Pedram|Goggins, Michael|Maitra, Anirban|Eshleman, James R
PMID: 19815696
64.
Journal: Cancer Sci. 2010 Jan;101(1):54-9.
Title: Identification of transforming activity of free fatty acid receptor 2 by retroviral expression screening.
Author: Hatanaka, Hisashi|Tsukui, Mamiko|Takada, Shuji|Kurashina, Kentaro|Choi, Young Lim|Soda, Manabu|Yamashita, Yoshihiro|Haruta, Hidenori|Hamada, Toru|Ueno, Toshihide|Tamada, Kiichi|Hosoya, Yoshinori|Sata, Naohiro|Yasuda, Yoshikazu|Nagai, Hideo|Sugano, Kentaro
PMID: 19780758
65.
Journal: Biochem Biophys Res Commun. 2010 Apr 30;395(2):258-63.
Title: Long-term culture following ES-like gene-induced reprogramming elicits an aggressive phenotype in mutated cholangiocellular carcinoma cells.
Author: Nagai, Ken-ichi|Ishii, Hideshi|Miyoshi, Norikatsu|Hoshino, Hiromitsu|Saito, Toshiyuki|Sato, Tetsuya|Tomimaru, Yoshito|Kobayashi, Shogo|Nagano, Hiroaki|Sekimoto, Mitsugu|Doki, Yuichiro|Mori, Masaki
PMID: 20381452
66.
Journal: BMC Cancer. 2010 Jun 18;10:302.
Title: Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines.
Author: Xu, Ling|Hausmann, Martin|Dietmaier, Wolfgang|Kellermeier, Silvia|Pesch, Theresa|Stieber-Gunckel, Manuela|Lippert, Elisabeth|Klebl, Frank|Rogler, Gerhard
PMID: 20565817
67.
Journal: Rev Med Chil. 2010 May;138(5):595-604.
Title: [Genetic alterations in preneoplastic and neoplastic injuries of the gallbladder].
Author: Castillo, Jonathan|Garcia, Patricia|Roa, Juan Carlos
PMID: 20668816
68.
Journal: Pancreatology. 2010;10(4):429-33.
Title: DNA mutational differences in cytological specimens from pancreatic cancer and cholangiocarcinoma.
Author: Fasanella, Kenneth E|Krasinskas, Alyssa|Schoedel, Karen E|Sasatomi, Eizaburo|Slivka, Adam|Whitcomb, David C|Sanders, Michael|Nodit, Laurentia|Raab, Stephen|McGrath, Kevin M|Ohori, N Paul|Khalid, Asif
PMID: 20720444
69.
Journal: J Mol Diagn. 2010 Nov;12(6):780-6.
Title: Comparison of KRAS mutation analysis and FISH for detecting pancreatobiliary tract cancer in cytology specimens collected during endoscopic retrograde cholangiopancreatography.
Author: Kipp, Benjamin R|Fritcher, Emily G Barr|Clayton, Amy C|Gores, Gregory J|Roberts, Lewis R|Zhang, Jun|Levy, Michael J|Halling, Kevin C
PMID: 20864634
70.
Journal: Biomed Pharmacother. 2011 Feb;65(1):22-6.
Title: KRAS and PIK3CA but not BRAF genes are frequently mutated in Chinese cholangiocarcinoma patients.
Author: Xu, Rui Feng|Sun, Ji Ping|Zhang, Shi Rong|Zhu, Guan Shan|Li, Li Bo|Liao, Yu Lin|Xie, Jian Ming|Liao, Wang Jun
PMID: 21051183
71.
Journal: BMC Cancer. 2011 Feb 8;11:60.
Title: Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.
Author: Deshpande, Vikram|Nduaguba, Afamefuna|Zimmerman, Stephanie M|Kehoe, Sarah M|Macconaill, Laura E|Lauwers, Gregory Y|Ferrone, Cristina|Bardeesy, Nabeel|Zhu, Andrew X|Hezel, Aram F
PMID: 21303542
72.
Journal: Appl Immunohistochem Mol Morphol. 2011 Mar;19(2):133-40.
Title: Mutations in the RAS/RAF/MAP kinase pathway commonly occur in gallbladder adenomas but are uncommon in gallbladder adenocarcinomas.
Author: Pai, Rish K|Mojtahed, Kaveh|Pai, Reetesh K
PMID: 21307665
73.
Journal: Genet Test Mol Biomarkers. 2011 Jun;15(6):431-4.
Title: A novel polymorphism in codon 25 of the KRAS gene associated with gallbladder carcinoma patients of the eastern part of India.
Author: Pramanik, Vishmadeb|Sarkar, Biswanath N|Kar, Madhuchanda|Das, Gautam|Malay, Barman K|Sufia, Khannam K|Lakkakula, Bhaskar V K S|Vadlamudi, Rao R
PMID: 21375404
74.
Journal: Semin Liver Dis. 2011 May;31(2):173-87.
Title: Genetics of hepatobiliary carcinogenesis.
Author: Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 21538283
75.
Journal: World J Clin Oncol. 2011 Mar 10;2(3):158-63.
Title: Recent progress and limitations of chemotherapy for pancreatic and biliary tract cancers.
Author: Tada, Minoru|Nakai, Yousuke|Sasaki, Takashi|Hamada, Tsuyoshi|Nagano, Rie|Mohri, Dai|Miyabayashi, Koji|Yamamoto, Keisuke|Kogure, Hirofumi|Kawakubo, Kazumichi|Ito, Yukiko|Yamamoto, Natsuyo|Sasahira, Naoki|Hirano, Kenji|Ijichi, Hideaki|Tateishi, Keishuke|Isa
PMID: 21611090
76.
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Author: Leone, Francesco|Marino, Donatella|Cereda, Stefano|Filippi, Roberto|Belli, Carmen|Spadi, Rosella|Nasti, Guglielmo|Montano, Massimo|Amatu, Alessio|Aprile, Giuseppe|Cagnazzo, Celeste|Fasola, Gianpiero|Siena, Salvatore|Ciuffreda, Libero|Reni, Michele|Agliett
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Journal: Ann Surg Oncol. 2016 May;23(5):1699-707.
Title: Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.
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Journal: Mod Pathol. 2016 Mar;29(3):293-301.
Title: Cholangiocarcinoma with intraductal tubular growth pattern versus intraductal papillary growth pattern.
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Journal: Cancer Cell. 2016 Feb 8;29(2):229-40.
Title: Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma.
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Journal: BMC Cancer. 2016 Feb 11;16:90.
Title: Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation.
Author: Cavalloni, Giuliana|Peraldo-Neia, Caterina|Sassi, Francesco|Chiorino, Giovanna|Sarotto, Ivana|Aglietta, Massimo|Leone, Francesco
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Journal: J Gastrointest Surg. 2016 May;20(5):953-9.
Title: Intra-pancreatic Distal Bile Duct Carcinoma is Morphologically, Genetically, and Clinically Distinct from Pancreatic Ductal Adenocarcinoma.
Author: Deshpande, Vikram|Konstantinidis, Ioannis T|Castillo, Carlos Fernandez-Del|Hezel, Aram F|Haigis, Kevin M|Ting, David T|Bardeesy, Nabeel|Goyal, Lipika|Zhu, Andrew X|Warshaw, Andrew L|Lillemoe, Keith D|Ferrone, Cristina R
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Journal: Oncotarget. 2016 Apr 26;7(17):23825-36.
Title: Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations.
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Journal: Sci Rep. 2016 Apr 1;6:23899.
Title: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
Author: Ikenoue, Tsuneo|Terakado, Yumi|Nakagawa, Hayato|Hikiba, Yohko|Fujii, Tomoaki|Matsubara, Daisuke|Noguchi, Rei|Zhu, Chi|Yamamoto, Keisuke|Kudo, Yotaro|Asaoka, Yoshinari|Yamaguchi, Kiyoshi|Ijichi, Hideaki|Tateishi, Keisuke|Fukushima, Noriyoshi|Maeda, Shin|Ko
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Journal: Oncotarget. 2016 Jul 19;7(29):46750-46767.
Title: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
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Journal: Oncotarget. 2016 Jun 21;7(25):37857-37867.
Title: Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206.
Author: Wang, Shou-Hua|Zhang, Wen-Jie|Wu, Xiao-Cai|Zhang, Ming-Di|Weng, Ming-Zhe|Zhou, Di|Wang, Jian-Dong|Quan, Zhi-Wei
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Journal: Am J Surg Pathol. 2016 Aug;40(8):1021-30.
Title: Distinct Clinicopathologic and Genetic Features of 2 Histologic Subtypes of Intrahepatic Cholangiocarcinoma.
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Journal: Transl Oncol. 2016 Jun;9(3):173-8.
Title: Genomic Alterations in Biliary Tract Cancer Using Targeted Sequencing.
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Journal: Am J Clin Pathol. 2016 Jun;145(6):815-25.
Title: Loss of ARID1A Expression Presents a Novel Pathway of Carcinogenesis in Biliary Carcinomas.
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Journal: Cancer Chemother Pharmacol. 2016 Aug;78(2):361-7.
Title: TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer.
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Journal: Histopathology. 2016 Dec;69(6):950-961.
Title: Comparative clinicopathological study of biliary intraductal papillary neoplasms and papillary cholangiocarcinomas.
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Journal: Oncol Lett. 2016 Sep;12(3):2210-2216. Epub 2016 Jul 15.
Title: APC promoter is frequently methylated in pancreatic juice of patients with pancreatic carcinomas or periampullary tumors.
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Journal: J Cancer Res Clin Oncol. 2016 Dec;142(12):2577-2583. Epub 2016 Sep 12.
Title: A let-7 microRNA binding site polymorphism in the KRAS 3'UTR is associated with increased risk and reduced survival for gallbladder cancer in North Indian population.
Author: Kazmi, Hasan Raza|Chandra, Abhijit|Kumar, Saket|Satyam, Leena Khare|Gupta, Annapurna|Nigam, Jaya|Srivastava, Meenu|Mittal, Balraj
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Journal: Cancer. 2016 Dec 15;122(24):3838-3847.
Title: Biliary cancer: Utility of next-generation sequencing for clinical management.
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Journal: Curr Treat Options Oncol. 2016 Nov;17(11):58.
Title: Genomic Profiling of Biliary Tract Cancers and Implications for Clinical Practice.
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Journal: Crit Rev Oncol Hematol. 2016 Nov;107:111-118.
Title: Molecular characteristics of biliary tract cancer.
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Journal: Chin Clin Oncol. 2016 Oct;5(5):67.
Title: Gallbladder cancer: South American experience.
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Journal: Jpn Clin Med. 2016 Dec 13;7:33-39.
Title: KRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers.
Author: Yokoyama, Masaaki|Ohnishi, Hiroaki|Ohtsuka, Kouki|Matsushima, Satsuki|Ohkura, Yasuo|Furuse, Junji|Watanabe, Takashi|Mori, Toshiyuki|Sugiyama, Masanori
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Journal: J Formos Med Assoc. 2017 Jun;116(6):464-468.
Title: Mutation analysis and copy number changes of KRAS and BRAF genes in Taiwanese cases of biliary tract cholangiocarcinoma.
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Journal: J Formos Med Assoc. 2017 Mar;116(3):214.
Title: KRAS mutation in biliary tract cholangiocarcinoma.
Author: Yasri, Sora|Wiwanitkit, Viroj
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Journal: Sci Rep. 2017 Jan 3;7:39567.
Title: Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
Author: Ikenoue, Tsuneo|Terakado, Yumi|Nakagawa, Hayato|Hikiba, Yohko|Fujii, Tomoaki|Matsubara, Daisuke|Noguchi, Rei|Zhu, Chi|Yamamoto, Keisuke|Kudo, Yotaro|Asaoka, Yoshinari|Yamaguchi, Kiyoshi|Ijichi, Hideaki|Tateishi, Keisuke|Fukushima, Noriyoshi|Maeda, Shin|Ko
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Journal: Pathol Res Pract. 2017 Apr;213(4):381-388.
Title: Concurrent MET copy number gain and KRAS mutation is a poor prognostic factor in pancreatobiliary subtype ampullary cancers.
Author: Kwon, Mi Jung|Kim, Jeong Won|Jeon, Jang Yong|Nam, Eun Sook|Cho, Seong Jin|Park, Hye-Rim|Min, Soo Kee|Seo, Jinwon|Min, Kyueng-Whan|Choe, Ji-Young|Lee, Hye Kyung
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Journal: Am J Cancer Res. 2017 Mar 1;7(3):484-502. eCollection 2017.
Title: Genomic and proteomic characterization of ARID1A chromatin remodeller in ampullary tumors.
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Journal: Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3806-E3815.
Title: Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
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Journal: Mol Cells. 2017 May 31;40(5):363-370.
Title: L1 Cell Adhesion Molecule Promotes Migration and Invasion via JNK Activation in Extrahepatic Cholangiocarcinoma Cells with Activating KRAS Mutation.
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Journal: Cancer Cell. 2017 Jun 12;31(6):771-789.e6.
Title: Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.
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Journal: Oncol Lett. 2017 Jul;14(1):877-884.
Title: Genetic alterations in Japanese extrahepatic biliary tract cancer.
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Journal: Pathol Res Pract. 2017 Aug;213(8):1010-1013.
Title: Adenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components.
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Journal: Ecancermedicalscience. 2017 Aug 7;11:757.
Title: Mutational frequency of KRAS, NRAS, IDH2, PIK3CA, and EGFR in North Indian gallbladder cancer patients.
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Journal: World J Gastrointest Oncol. 2017 Oct 15;9(10):407-415.
Title: Ampullary cancer of intestinal origin and duodenal cancer - A logical clinical and therapeutic subgroup in periampullary cancer.
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Journal: Tumour Biol. 2017 Nov;39(11):1010428317725925.
Title: Establishment of cholangiocarcinoma cell lines from patients in the endemic area of liver fluke infection in Thailand.
Author: Saensa-Ard, Sunitta|Leuangwattanawanit, Saman|Senggunprai, Laddawan|Namwat, Nisana|Kongpetch, Sarinya|Chamgramol, Yaovalux|Loilome, Watcharin|Khansaard, Walaiporn|Jusakul, Apinya|Prawan, Auemduan|Pairojkul, Chawalit|Khantikeo, Narong|Yongvanit, Puangrat|K
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Journal: Oncoscience. 2017 Oct 23;4(9-10):131-138.
Title: Kras(G12D) upregulates Notch signaling to induce gallbladder tumorigenesis in mice.
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Journal: Medicine (Baltimore). 2017 Dec;96(50):e9217.
Title: Utility of KRAS mutational analysis in the preoperative diagnosis of synchronous pancreatic cancer and intrahepatic cholangiocarcinoma: A case report.
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Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1454-1460.
Title: Targeting cholangiocarcinoma.
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Journal: Hepatology. 2018 Sep;68(3):949-963.
Title: Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
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Journal: Am J Surg Pathol. 2018 Apr;42(4):512-521.
Title: MDM2 Amplification in Intrahepatic Cholangiocarcinomas: Its Relationship With Large-Duct Type Morphology and Uncommon KRAS Mutations.
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Journal: Cancer Res Treat. 2018 Jan 8. pii: crt.2017.526.
Title: Multicenter Phase II Study of Oxaliplatin, Irinotecan, and S-1 as First-line Treatment for Patients with Recurrent or Metastatic Biliary Tract Cancer.
Author: Yoo, Changhoon|Han, Boram|Kim, Hyeong Su|Kim, Kyu-Pyo|Kim, Deokhoon|Jeong, Jae Ho|Lee, Jae-Lyun|Kim, Tae Won|Kim, Jung Han|Choi, Dae Ro|Ha, Hong Il|Seo, Jinwon|Chang, Heung-Moon|Ryoo, Baek-Yeol|Zang, Dae Young
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Journal: Br J Cancer. 2018 Feb 20;118(4):462-470.
Title: Phase I dose-escalation study of copanlisib in combination with gemcitabine or cisplatin plus gemcitabine in patients with advanced cancer.
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Journal: Cancer Control. 2018 Jan-Mar;25(1):1073274817744658.
Title: Primary Liver Cancers, Part 2: Progression Pathways and Carcinogenesis.
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Journal: J Hepatol. 2018 May;68(5):959-969.
Title: Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.
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Journal: Sci Rep. 2018 Jan 31;8(1):2021.
Title: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.
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Journal: Eur J Cancer. 2018 Mar;92:11-19.
Title: PICCA study: panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer-a randomised biomarker-driven clinical phase II AIO study.
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Journal: Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title: Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
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Journal: Cancer Lett. 2018 May 1;421:161-169.
Title: Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author: Lin, Yun-Kai|Fang, Zheng|Jiang, Tian-Yi|Wan, Zheng-Hua|Pan, Yu-Fei|Ma, Yun-Han|Shi, Yuan-Yuan|Tan, Ye-Xiong|Dong, Li-Wei|Zhang, Yong-Jie|Wang, Hong-Yang
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Journal: Br J Cancer. 2018 Apr;118(7):966-971.
Title: Phase II study of everolimus (RAD001) monotherapy as first-line treatment in advanced biliary tract cancer with biomarker exploration: the RADiChol Study.
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Journal: J Hepatol. 2018 Jul;69(1):89-98.
Title: Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma.
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Journal: Cancer Sci. 2018 May;109(5):1282-1291.
Title: Molecular genomic landscapes of hepatobiliary cancer.
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Journal: Anticancer Res. 2018 Apr;38(4):1979-1986.
Title: The Novel Selective Pan-TRK Inhibitor ONO-7579 Exhibits Antitumor Efficacy Against Human Gallbladder Cancer In Vitro.
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Journal: J Transl Med. 2018 Apr 11;16(1):95.
Title: Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by (18)F-FDG-PET is associated with the KRAS mutation status and prognosis.
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Journal: Histopathology. 2018 Aug;73(2):259-272.
Title: Interleukin-33 overexpression reflects less aggressive tumour features in large-duct type cholangiocarcinomas.
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Journal: Hum Pathol. 2018 Aug;78:131-137.
Title: Mucinous intrahepatic cholangiocarcinoma: a distinct variant.
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Journal: Invest New Drugs. 2018 May 22. pii: 10.1007/s10637-018-0600-2.
Title: Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer.
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Journal: Mutat Res. 2018 Apr - Jun;776:10-22.
Title: Ampullary carcinoma-A genetic perspective.
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Journal: Clin Cancer Res. 2018 Sep 1;24(17):4154-4161.
Title: Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention.
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Journal: Cancer Res. 2018 Aug 15;78(16):4445-4451.
Title: Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.
Author: Hill, Margaret A|Alexander, William B|Guo, Bing|Kato, Yasutaka|Patra, Krushna|O'Dell, Michael R|McCall, Matthew N|Whitney-Miller, Christa L|Bardeesy, Nabeel|Hezel, Aram F
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Journal: Sci Rep. 2018 Jul 13;8(1):10637.
Title: ACGH detects distinct genomic alterations of primary intrahepatic cholangiocarcinomas and matched lymph node metastases and identifies a poor prognosis subclass.
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Journal: Cancer Biol Ther. 2018 Aug 1:1-11.
Title: Pancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation.
Author: Arnoletti, J Pablo|Fanaian, Na'im|Reza, Joseph|Sause, Ryan|Almodovar, Alvin Jo|Srivastava, Milan|Patel, Swati|Veldhuis, Paula P|Griffith, Elizabeth|Shao, Yai-Ping|Zhu, Xiang|Litherland, Sally A
PMID: 30067440
197.
Journal: Front Genet. 2018 Aug 15;9:309.
Title: Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type.
Author: Shiao, Meng-Shin|Chiablaem, Khajeelak|Charoensawan, Varodom|Ngamphaiboon, Nuttapong|Jinawath, Natini
PMID: 30158952
198.
Journal: Int J Cancer. 2018 Oct 10.
Title: ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in Early Stage Gallbladder Cancer.
Author: Iyer, Prajish|Shrikhande, Shailesh V|Ranjan, Malika|Joshi, Asim|Gardi, Nilesh|Prasad, Ratnam|Dharavath, Bhasker|Thorat, Rahul|Salunkhe, Sameer|Sahoo, Bikram|Chandrani, Pratik|Kore, Hitesh|Mohanty, Bhabani|Chaudhari, Vikram|Choughule, Anuradha|Kawle, Dhana
PMID: 30304546
199.
Journal: Virchows Arch. 2018 Oct 23. pii: 10.1007/s00428-018-2476-0.
Title: EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma.
Author: Tanaka, Mariko|Shibahara, Junji|Ishikawa, Shumpei|Ushiku, Tetsuo|Morikawa, Teppei|Shinozaki-Ushiku, Aya|Hayashi, Akimasa|Misumi, Kento|Tanaka, Atsushi|Katoh, Hiroto|Sakuma, Kei|Kokudo, Takashi|Inagaki, Yoshinori|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa
PMID: 30349952