Primary Site >> Pancreatic Cancer
Gene >> KDR
| 1. | |||||||||||
| Journal: | Int J Cancer. 2000 Jan 1;85(1):27-34. | ||||||||||
| Title: | Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. | ||||||||||
| Author: | Itakura, J|Ishiwata, T|Shen, B|Kornmann, M|Korc, M | ||||||||||
| PMID: | 10585578 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterology. 2000 Nov;119(5):1358-72. | ||||||||||
| Title: | De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop. | ||||||||||
| Author: | von Marschall, Z|Cramer, T|Hocker, M|Burde, R|Plath, T|Schirner, M|Heidenreich, R|Breier, G|Riecken, E O|Wiedenmann, B|Rosewicz, S | ||||||||||
| PMID: | 11054395 | ||||||||||
| 3. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4605-10. Epub 2001 Mar 27. | ||||||||||
| Title: | Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. | ||||||||||
| Author: | Kuo, C J|Farnebo, F|Yu, E Y|Christofferson, R|Swearingen, R A|Carter, R|von Recum, H A|Yuan, J|Kamihara, J|Flynn, E|D'Amato, R|Folkman, J|Mulligan, R C | ||||||||||
| PMID: | 11274374 | ||||||||||
| 4. | |||||||||||
| Journal: | Histol Histopathol. 2001 Apr;16(2):359-75. | ||||||||||
| Title: | Expression of VEGF-C and activation of its receptors VEGFR-2 and VEGFR-3 in trophoblast. | ||||||||||
| Author: | Dunk, C|Ahmed, A | ||||||||||
| PMID: | 11332691 | ||||||||||
| 5. | |||||||||||
| Journal: | Surgery. 2002 Nov;132(5):857-65. | ||||||||||
| Title: | Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice. | ||||||||||
| Author: | Tseng, Jennifer F|Farnebo, Filip A|Kisker, Oliver|Becker, Christian M|Kuo, Calvin J|Folkman, Judah|Mulligan, Richard C | ||||||||||
| PMID: | 12464871 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2003 Sep 15;63(18):5978-91. | ||||||||||
| Title: | CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. | ||||||||||
| Author: | Ruggeri, Bruce|Singh, Jasbir|Gingrich, Diane|Angeles, Thelma|Albom, Mark|Yang, Shi|Chang, Hong|Robinson, Candy|Hunter, Kathryn|Dobrzanski, Pawel|Jones-Bolin, Susan|Pritchard, Sonya|Aimone, Lisa|Klein-Szanto, Andres|Herbert, Jean-Marc|Bono, Francoise|Schae | ||||||||||
| PMID: | 14522925 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer. 2004 Nov 15;101(10):2341-50. | ||||||||||
| Title: | Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors. | ||||||||||
| Author: | Li, Min|Yang, Hui|Chai, Hong|Fisher, William E|Wang, Xiaoping|Brunicardi, F Charles|Yao, Qizhi|Chen, Changyi | ||||||||||
| PMID: | 15476280 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):678-89. | ||||||||||
| Title: | Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668. | ||||||||||
| Author: | Davis, Darren W|Takamori, Ryan|Raut, Chandrajit P|Xiong, Henry Q|Herbst, Roy S|Stadler, Walter M|Heymach, John V|Demetri, George D|Rashid, Asif|Shen, Yu|Wen, Sijin|Abbruzzese, James L|McConkey, David J | ||||||||||
| PMID: | 15701856 | ||||||||||
| 9. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2005 May;5(3):171-93. | ||||||||||
| Title: | Molecularly targeted therapy for gastrointestinal cancer. | ||||||||||
| Author: | Wiedmann, Marcus W|Caca, Karel | ||||||||||
| PMID: | 15892618 | ||||||||||
| 10. | |||||||||||
| Journal: | Neoplasia. 2005 Jul;7(7):696-704. | ||||||||||
| Title: | Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. | ||||||||||
| Author: | Yokoi, Kenji|Kim, Sun-Jin|Thaker, Premal|Yazici, Sertac|Nam, Do-Hyun|He, Junqin|Sasaki, Takamitsu|Chiao, Paul J|Sclabas, Guido M|Abbruzzese, James L|Hamilton, Stanley R|Fidler, Isaiah J | ||||||||||
| PMID: | 16026649 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2005 Nov 15;65(22):10371-80. | ||||||||||
| Title: | Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. | ||||||||||
| Author: | Yokoi, Kenji|Sasaki, Takamitsu|Bucana, Corazon D|Fan, Dominic|Baker, Cheryl H|Kitadai, Yasuhiko|Kuwai, Toshio|Abbruzzese, James L|Fidler, Isaiah J | ||||||||||
| PMID: | 16288027 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer. 2006 Apr 15;106(8):1677-84. | ||||||||||
| Title: | Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. | ||||||||||
| Author: | Chung, Gina G|Yoon, Harry H|Zerkowski, Maciej P|Ghosh, Sriparna|Thomas, Laurie|Harigopal, Malini|Charette, Lori A|Salem, Ronald R|Camp, Robert L|Rimm, David L|Burtness, Barbara A | ||||||||||
| PMID: | 16532435 | ||||||||||
| 13. | |||||||||||
| Journal: | Drug Resist Updat. 2006 Feb-Apr;9(1-2):1-18. Epub 2006 Apr 18. | ||||||||||
| Title: | Tyrosine kinase inhibitors and gemcitabine: new treatment options in pancreatic cancer? | ||||||||||
| Author: | Kleespies, Axel|Jauch, Karl-Walter|Bruns, Christiane J | ||||||||||
| PMID: | 16621676 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Cancer Res. 2006 Apr 15;12(8):2628-33. | ||||||||||
| Title: | Roles of nitric oxide synthase inhibition and vascular endothelial growth factor receptor-2 inhibition on vascular morphology and function in an in vivo model of pancreatic cancer. | ||||||||||
| Author: | Camp, E Ramsay|Yang, Anthony|Liu, Wenbiao|Fan, Fan|Somcio, Ray|Hicklin, Daniel J|Ellis, Lee M | ||||||||||
| PMID: | 16638876 | ||||||||||
| 15. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2006 Jun 23;345(1):292-301. Epub 2006 May 2. | ||||||||||
| Title: | Regulation of vascular endothelial growth factor receptor-2 expression in pancreatic cancer cells by Sp proteins. | ||||||||||
| Author: | Higgins, Kelly J|Abdelrahim, Maen|Liu, Shengxi|Yoon, Kyungsil|Safe, Stephen | ||||||||||
| PMID: | 16678129 | ||||||||||
| 16. | |||||||||||
| Journal: | Ann Surg Oncol. 2006 Aug;13(8):1145-55. | ||||||||||
| Title: | Selective blockade of vascular endothelial growth factor receptor 2 with an antibody against tumor-derived vascular endothelial growth factor controls the growth of human pancreatic adenocarcinoma xenografts. | ||||||||||
| Author: | Holloway, Shane E|Beck, Adam W|Shivakumar, Latha|Shih, Jessica|Fleming, Jason B|Brekken, Rolf A | ||||||||||
| PMID: | 16791450 | ||||||||||
| 17. | |||||||||||
| Journal: | Br J Cancer. 2007 Oct 22;97(8):1116-23. Epub 2007 Sep 25. | ||||||||||
| Title: | Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines. | ||||||||||
| Author: | Hurt, E M|Thomas, S B|Peng, B|Farrar, W L | ||||||||||
| PMID: | 17895890 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2008 Jul 1;71(3):873-9. | ||||||||||
| Title: | SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation. | ||||||||||
| Author: | Cuneo, Kyle C|Geng, Ling|Fu, Allie|Orton, Darren|Hallahan, Dennis E|Chakravarthy, Anuradha Bapsi | ||||||||||
| PMID: | 18514780 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2008 Jun 1;68(11):4340-6. | ||||||||||
| Title: | Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice. | ||||||||||
| Author: | Dineen, Sean P|Lynn, Kristi D|Holloway, Shane E|Miller, Andrew F|Sullivan, James P|Shames, David S|Beck, Adam W|Barnett, Carlton C|Fleming, Jason B|Brekken, Rolf A | ||||||||||
| PMID: | 18519694 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Cancer Ther. 2008 Nov;7(11):3509-18. | ||||||||||
| Title: | Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes. | ||||||||||
| Author: | Lang, Sven A|Schachtschneider, Philipp|Moser, Christian|Mori, Akira|Hackl, Christina|Gaumann, Andreas|Batt, David|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver | ||||||||||
| PMID: | 19001434 | ||||||||||
| 21. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Nov 15;14(22):7272-83. | ||||||||||
| Title: | Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3. | ||||||||||
| Author: | Hu-Lowe, Dana D|Zou, Helen Y|Grazzini, Maren L|Hallin, Max E|Wickman, Grant R|Amundson, Karin|Chen, Jeffrey H|Rewolinski, David A|Yamazaki, Shinji|Wu, Ellen Y|McTigue, Michele A|Murray, Brion W|Kania, Robert S|O'Connor, Patrick|Shalinsky, David R|Bender, | ||||||||||
| PMID: | 19010843 | ||||||||||
| 22. | |||||||||||
| Journal: | BMC Cancer. 2008 Nov 27;8:352. | ||||||||||
| Title: | The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer. | ||||||||||
| Author: | Dineen, Sean P|Sullivan, Laura A|Beck, Adam W|Miller, Andrew F|Carbon, Juliet G|Mamluk, Roni|Wong, Henry|Brekken, Rolf A | ||||||||||
| PMID: | 19038046 | ||||||||||
| 23. | |||||||||||
| Journal: | Transl Oncol. 2008 Dec;1(4):195-201. | ||||||||||
| Title: | Enzastaurin, an inhibitor of PKCbeta, Enhances Antiangiogenic Effects and Cytotoxicity of Radiation against Endothelial Cells. | ||||||||||
| Author: | Spalding, Aaron C|Zeitlin, Benjamin D|Wilder-Romans, Kari|Davis, Mary E|Nor, Jacques E|Lawrence, Theodore S|Ben-Josef, Edgar | ||||||||||
| PMID: | 19043530 | ||||||||||
| 24. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2008 Nov;35(12):2271-3. | ||||||||||
| Title: | [A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer]. | ||||||||||
| Author: | Kim, Dal Ho|Shiozawa, Shunichi|Usui, Takebumi|Yoshimatsu, Kazuhiko|Otani, Taisuke|Tsunoda, Takuya|Nakamura, Yusuke|Ogawa, Kenji | ||||||||||
| PMID: | 19106593 | ||||||||||
| 25. | |||||||||||
| Journal: | Biologics. 2008 Dec;2(4):707-15. | ||||||||||
| Title: | Small molecule tyrosine kinase inhibitors in pancreatic cancer. | ||||||||||
| Author: | Gupta, Sachin|El-Rayes, Bassel F | ||||||||||
| PMID: | 19707451 | ||||||||||
| 26. | |||||||||||
| Journal: | J Cell Physiol. 2009 Apr;219(1):209-18. | ||||||||||
| Title: | The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis. | ||||||||||
| Author: | Zou, Gang-Ming|Karikari, Collins|Kabe, Yasuaki|Handa, Hiroshi|Anders, Robert A|Maitra, Anirban | ||||||||||
| PMID: | 19097035 | ||||||||||
| 27. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2009 Feb;36(2):187-92. | ||||||||||
| Title: | [Treatments of epithelial ovarian cancer by histologic subtype]. | ||||||||||
| Author: | Sugiyama, Toru|Kumagai, Seisuke|Hatayama, Shinya | ||||||||||
| PMID: | 19223734 | ||||||||||
| 28. | |||||||||||
| Journal: | Anticancer Res. 2009 Jun;29(6):1999-2007. | ||||||||||
| Title: | Prioritization of EGFR/IGF-IR/VEGFR2 combination targeted therapies utilizing cancer models. | ||||||||||
| Author: | Tonra, James R|Corcoran, Erik|Deevi, Dhanvanthri S|Steiner, Philipp|Kearney, Jessica|Li, Huiling|Ludwig, Dale L|Zhu, Zhenping|Witte, Larry|Surguladze, David|Hicklin, Daniel J | ||||||||||
| PMID: | 19528458 | ||||||||||
| 29. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Jul;8(7):1761-71. | ||||||||||
| Title: | Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts. | ||||||||||
| Author: | Roland, Christina L|Dineen, Sean P|Lynn, Kristi D|Sullivan, Laura A|Dellinger, Michael T|Sadegh, Leila|Sullivan, James P|Shames, David S|Brekken, Rolf A | ||||||||||
| PMID: | 19567820 | ||||||||||
| 30. | |||||||||||
| Journal: | Nat Rev Clin Oncol. 2009 Oct;6(10):569-79. | ||||||||||
| Title: | An overview of small-molecule inhibitors of VEGFR signaling. | ||||||||||
| Author: | Ivy, S Percy|Wick, Jeannette Y|Kaufman, Bennett M | ||||||||||
| PMID: | 19736552 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Sci. 2010 Feb;101(2):433-9. | ||||||||||
| Title: | Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer. | ||||||||||
| Author: | Miyazawa, Motoki|Ohsawa, Ryuji|Tsunoda, Takuya|Hirono, Seiko|Kawai, Manabu|Tani, Masaji|Nakamura, Yusuke|Yamaue, Hiroki | ||||||||||
| PMID: | 19930156 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Sci. 2010 Jun;101(6):1529-35. | ||||||||||
| Title: | Significance of phospho-vascular endothelial growth factor receptor-2 expression in pancreatic cancer. | ||||||||||
| Author: | Doi, Yosuke|Yashiro, Masakazu|Yamada, Nobuya|Amano, Ryosuke|Ohira, Go|Komoto, Masahiro|Noda, Satoru|Kashiwagi, Shinichiro|Kato, Yukihiro|Fuyuhiro, Yuhiko|Hirakawa, Kosei | ||||||||||
| PMID: | 20367641 | ||||||||||
| 33. | |||||||||||
| Journal: | Mol Imaging Biol. 2010 Dec;12(6):570-5. | ||||||||||
| Title: | Bioluminescence imaging of angiogenesis in a murine orthotopic pancreatic cancer model. | ||||||||||
| Author: | Angst, Eliane|Chen, Monica|Mojadidi, Michelle|Hines, O Joe|Reber, Howard A|Eibl, Guido | ||||||||||
| PMID: | 20376570 | ||||||||||
| 34. | |||||||||||
| Journal: | Mol Pharmacol. 2010 Aug;78(2):226-36. | ||||||||||
| Title: | Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a. | ||||||||||
| Author: | Jutooru, Indira|Chadalapaka, Gayathri|Abdelrahim, Maen|Basha, Md Riyaz|Samudio, Ismael|Konopleva, Marina|Andreeff, Michael|Safe, Stephen | ||||||||||
| PMID: | 20488920 | ||||||||||
| 35. | |||||||||||
| Journal: | Chemotherapy. 2010;56(4):303-12. | ||||||||||
| Title: | Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells. | ||||||||||
| Author: | Ricciardi, Simona|Mey, Valentina|Nannizzi, Sara|Pasqualetti, Giuseppe|Crea, Francesco|Del Tacca, Mario|Danesi, Romano | ||||||||||
| PMID: | 20714148 | ||||||||||
| 36. | |||||||||||
| Journal: | Neoplasia. 2010 Oct;12(10):797-806. | ||||||||||
| Title: | Specific targeting of tumor endothelial cells by a shiga-like toxin-vascular endothelial growth factor fusion protein as a novel treatment strategy for pancreatic cancer. | ||||||||||
| Author: | Hotz, Birgit|Backer, Marina V|Backer, Joseph M|Buhr, Heinz-J|Hotz, Hubert G | ||||||||||
| PMID: | 20927318 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Res. 2010 Nov 1;70(21):8812-21. | ||||||||||
| Title: | Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. | ||||||||||
| Author: | Qin, Jun|Chen, Xinpu|Yu-Lee, Li-Yuan|Tsai, Ming-Jer|Tsai, Sophia Y | ||||||||||
| PMID: | 20978203 | ||||||||||
| 38. | |||||||||||
| Journal: | Toxins (Basel). 2010 Sep;2(9):2242-57. | ||||||||||
| Title: | SLT-VEGF reduces lung metastases, decreases tumor recurrence, and improves survival in an orthotopic melanoma model. | ||||||||||
| Author: | Ackerman, Rachel|Backer, Joseph M|Backer, Marina|Skariah, Sini|Hamby, Carl V | ||||||||||
| PMID: | 22069683 | ||||||||||
| 39. | |||||||||||
| Journal: | Radiology. 2011 Mar;258(3):804-11. | ||||||||||
| Title: | Tumor angiogenic marker expression levels during tumor growth: longitudinal assessment with molecularly targeted microbubbles and US imaging. | ||||||||||
| Author: | Deshpande, Nirupama|Ren, Ying|Foygel, Kira|Rosenberg, Jarrett|Willmann, Jurgen K | ||||||||||
| PMID: | 21339349 | ||||||||||
| 40. | |||||||||||
| Journal: | Neoplasia. 2011 Mar;13(3):217-29. | ||||||||||
| Title: | Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo. | ||||||||||
| Author: | Canu, Bastianina|Fioravanti, Anna|Orlandi, Paola|Di Desidero, Teresa|Ali, Greta|Fontanini, Gabriella|Di Paolo, Antonello|Del Tacca, Mario|Danesi, Romano|Bocci, Guido | ||||||||||
| PMID: | 21390185 | ||||||||||
| 41. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Aug 15;17(16):5299-310. | ||||||||||
| Title: | Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition. | ||||||||||
| Author: | Allen, Elizabeth|Walters, Ian B|Hanahan, Douglas | ||||||||||
| PMID: | 21622725 | ||||||||||
| 42. | |||||||||||
| Journal: | Mol Cancer Ther. 2011 Nov;10(11):2157-67. | ||||||||||
| Title: | Targeting FGFR/PDGFR/VEGFR impairs tumor growth, angiogenesis, and metastasis by effects on tumor cells, endothelial cells, and pericytes in pancreatic cancer. | ||||||||||
| Author: | Taeger, Johannes|Moser, Christian|Hellerbrand, Claus|Mycielska, Maria E|Glockzin, Gabriel|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver|Lang, Sven A | ||||||||||
| PMID: | 21885862 | ||||||||||
| 43. | |||||||||||
| Journal: | PLoS One. 2011;6(10):e25799. | ||||||||||
| Title: | Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3. | ||||||||||
| Author: | Boreddy, Srinivas Reddy|Sahu, Ravi P|Srivastava, Sanjay K | ||||||||||
| PMID: | 22016776 | ||||||||||
| 44. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2011 Nov;38(12):1903-5. | ||||||||||
| Title: | [The development of a novel cancer vaccine using Peptide vaccine for patients with advanced pancreatic cancer]. | ||||||||||
| Author: | Miyazawa, Motoki|Yamaue, Hiroki | ||||||||||
| PMID: | 22202233 | ||||||||||
| 45. | |||||||||||
| Journal: | Invest New Drugs. 2012 Feb;30(1):382-6. | ||||||||||
| Title: | Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium. | ||||||||||
| Author: | Kindler, Hedy Lee|Wroblewski, Kristen|Wallace, James A|Hall, Michael J|Locker, Gershon|Nattam, Sreenivasa|Agamah, Edem|Stadler, Walter M|Vokes, Everett E | ||||||||||
| PMID: | 20803052 | ||||||||||
| 46. | |||||||||||
| Journal: | Ann Surg Oncol. 2012 Jul;19 Suppl 3:S464-74. | ||||||||||
| Title: | High expression of delta-like ligand 4 predicts poor prognosis after curative resection for pancreatic cancer. | ||||||||||
| Author: | Chen, Hai-Tao|Cai, Quan-Cai|Zheng, Jian-Ming|Man, Xiao-Hua|Jiang, Hui|Song, Bin|Jin, Gang|Zhu, Wei|Li, Zhao-Shen | ||||||||||
| PMID: | 21822553 | ||||||||||
| 47. | |||||||||||
| Journal: | Ann Surg Oncol. 2012 Aug;19(8):2733-43. | ||||||||||
| Title: | VEGF-A/VEGFR-2 signaling plays an important role for the motility of pancreas cancer cells. | ||||||||||
| Author: | Doi, Yosuke|Yashiro, Masakazu|Yamada, Nobuya|Amano, Ryosuke|Noda, Satoru|Hirakawa, Kosei | ||||||||||
| PMID: | 22207048 | ||||||||||
| 48. | |||||||||||
| Journal: | Clin Cancer Res. 2012 May 15;18(10):2838-49. | ||||||||||
| Title: | Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. | ||||||||||
| Author: | Speisky, Daniela|Duces, Aurelie|Bieche, Ivan|Rebours, Vinciane|Hammel, Pascal|Sauvanet, Alain|Richard, Stephane|Bedossa, Pierre|Vidaud, Michel|Murat, Arnaud|Niccoli, Patricia|Scoazec, Jean-Yves|Ruszniewski, Philippe|Couvelard, Anne | ||||||||||
| PMID: | 22461457 | ||||||||||
| 49. | |||||||||||
| Journal: | Eur J Clin Invest. 2012 Oct;42(10):1061-7. | ||||||||||
| Title: | Novel dual inhibitors of vascular endothelial growth factor and VEGFR2 receptor. | ||||||||||
| Author: | Nguyen, Jennifer P|Frost, Chelsea D|Lane, Meghan L|Skelton Iv, William P|Skelton, Michelle|Vesely, David L | ||||||||||
| PMID: | 22703300 | ||||||||||
| 50. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e42146. | ||||||||||
| Title: | Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis. | ||||||||||
| Author: | Lin, Sheng-Zhang|Wei, Wei-Tian|Chen, Hui|Chen, Kang-Jie|Tong, Hong-Fei|Wang, Zhao-Hong|Ni, Zhong-Lin|Liu, Hai-Bin|Guo, Hong-Chun|Liu, Dian-Lei | ||||||||||
| PMID: | 22876305 | ||||||||||
| 51. | |||||||||||
| Journal: | BMC Cancer. 2012 Aug 20;12:361. | ||||||||||
| Title: | Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer. | ||||||||||
| Author: | Niethammer, Andreas G|Lubenau, Heinz|Mikus, Gerd|Knebel, Philipp|Hohmann, Nicolas|Leowardi, Christine|Beckhove, Philipp|Akhisaroglu, Mustafa|Ge, Yingzi|Springer, Marco|Grenacher, Lars|Buchler, Markus W|Koch, Moritz|Weitz, Jurgen|Haefeli, Walter E|Schmitz- | ||||||||||
| PMID: | 22906006 | ||||||||||
| 52. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2012 Dec;343(3):617-27. | ||||||||||
| Title: | Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptor/platelet-derived growth factor receptor, and Src kinase families. | ||||||||||
| Author: | Glaser, Keith B|Li, Junling|Marcotte, Patrick A|Magoc, Terrance J|Guo, Jun|Reuter, David R|Tapang, Paul|Wei, Ru-Qi|Pease, Lori J|Bui, Mai H|Chen, Zehan|Frey, Robin R|Johnson, Eric F|Osterling, Donald J|Olson, Amanda M|Bouska, Jennifer J|Luo, Yanping|Curti | ||||||||||
| PMID: | 22935731 | ||||||||||
| 53. | |||||||||||
| Journal: | Pancreas. 2013 Apr;42(3):411-21. | ||||||||||
| Title: | Molecular markers for novel therapeutic strategies in pancreatic endocrine tumors. | ||||||||||
| Author: | Gilbert, Judith A|Adhikari, Laura J|Lloyd, Ricardo V|Halfdanarson, Thorvardur R|Muders, Michael H|Ames, Matthew M | ||||||||||
| PMID: | 23211371 | ||||||||||
| 54. | |||||||||||
| Journal: | Ann Oncol. 2013 May;24(5):1282-90. | ||||||||||
| Title: | VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma. | ||||||||||
| Author: | Uzunoglu, F G|Kolbe, J|Wikman, H|Gungor, C|Bohn, B A|Nentwich, M F|Reeh, M|Konig, A M|Bockhorn, M|Kutup, A|Mann, O|Izbicki, J R|Vashist, Y K | ||||||||||
| PMID: | 23293110 | ||||||||||
| 55. | |||||||||||
| Journal: | Br J Cancer. 2013 Mar 19;108(5):1052-60. | ||||||||||
| Title: | Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer. | ||||||||||
| Author: | Miles, D W|de Haas, S L|Dirix, L Y|Romieu, G|Chan, A|Pivot, X|Tomczak, P|Provencher, L|Cortes, J|Delmar, P R|Scherer, S J | ||||||||||
| PMID: | 23422754 | ||||||||||
| 56. | |||||||||||
| Journal: | J Cell Mol Med. 2013 Jun;17(6):792-9. | ||||||||||
| Title: | An intensified systemic trafficking of bone marrow-derived stem/progenitor cells in patients with pancreatic cancer. | ||||||||||
| Author: | Starzynska, Teresa|Dabkowski, Krzysztof|Blogowski, Wojciech|Zuba-Surma, Ewa|Budkowska, Marta|Salata, Daria|Dolegowska, Barbara|Marlicz, Wojciech|Lubikowski, Jerzy|Ratajczak, Mariusz Z | ||||||||||
| PMID: | 23672538 | ||||||||||
| 57. | |||||||||||
| Journal: | Pancreatology. 2013 Jul-Aug;13(4):415-22. | ||||||||||
| Title: | Efficacy and safety profile of combining agents against epidermal growth factor receptor or vascular endothelium growth factor receptor with gemcitabine-based chemotherapy in patients with advanced pancreatic cancer: a meta-analysis. | ||||||||||
| Author: | Tian, Wei|Ding, Wenping|Kim, Sungkyoung|Xu, Xiaoxing|Pan, Minggui|Chen, Siyu | ||||||||||
| PMID: | 23890141 | ||||||||||
| 58. | |||||||||||
| Journal: | Cell Signal. 2013 Dec;25(12):2587-603. | ||||||||||
| Title: | A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer. | ||||||||||
| Author: | Gilmour, Alanna M|Abdulkhalek, Samar|Cheng, Timothy S W|Alghamdi, Farah|Jayanth, Preethi|O'Shea, Leah K|Geen, Olivia|Arvizu, Luis A|Szewczuk, Myron R | ||||||||||
| PMID: | 23993964 | ||||||||||
| 59. | |||||||||||
| Journal: | PLoS One. 2013 Sep 4;8(9):e72480. | ||||||||||
| Title: | Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody. | ||||||||||
| Author: | Hernandez, Jose Luis|Padilla, Laura|Dakhel, Sheila|Coll, Toni|Hervas, Rosa|Adan, Jaume|Masa, Marc|Mitjans, Francesc|Martinez, Josep Maria|Coma, Silvia|Rodriguez, Laura|Noe, Veronique|Ciudad, Carlos J|Blasco, Francesc|Messeguer, Ramon | ||||||||||
| PMID: | 24023743 | ||||||||||
| 60. | |||||||||||
| Journal: | PLoS One. 2013 Sep 9;8(9):e73940. | ||||||||||
| Title: | DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ali, Naushad|Lightfoot, Stan A|Pantazis, Panayotis|Rao, Chinthalapally V|Postier, Russell G|Houchen, Courtney W | ||||||||||
| PMID: | 24040120 | ||||||||||
| 61. | |||||||||||
| Journal: | Oncoimmunology. 2013 Nov 1;2(11):e27010. | ||||||||||
| Title: | Immunological responses to a multi-peptide vaccine targeting cancer-testis antigens and VEGFRs in advanced pancreatic cancer patients. | ||||||||||
| Author: | Okuyama, Ryuji|Aruga, Atsushi|Hatori, Takashi|Takeda, Kazuyoshi|Yamamoto, Masakazu | ||||||||||
| PMID: | 24498547 | ||||||||||
| 62. | |||||||||||
| Journal: | Br J Cancer. 2014 Jan 21;110(2):320-9. | ||||||||||
| Title: | Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models. | ||||||||||
| Author: | Zhang, H|Hylander, B L|LeVea, C|Repasky, E A|Straubinger, R M|Adjei, A A|Ma, W W | ||||||||||
| PMID: | 24327018 | ||||||||||
| 63. | |||||||||||
| Journal: | PLoS One. 2014 Jan 9;9(1):e82209. | ||||||||||
| Title: | A phase I, dose-finding study of sorafenib in combination with gemcitabine and radiation therapy in patients with unresectable pancreatic adenocarcinoma: a Grupo Espanol Multidisciplinario en Cancer Digestivo (GEMCAD) study. | ||||||||||
| Author: | Aparicio, Jorge|Garcia-Mora, Carmen|Martin, Marta|Petriz, Ma Lourdes|Feliu, Jaime|Sanchez-Santos, Ma Elena|Ayuso, Juan Ramon|Fuster, David|Conill, Carlos|Maurel, Joan | ||||||||||
| PMID: | 24416138 | ||||||||||
| 64. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2014 May;63(5):479-89. | ||||||||||
| Title: | P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma. | ||||||||||
| Author: | Terashima, Takeshi|Mizukoshi, Eishiro|Arai, Kuniaki|Yamashita, Tatsuya|Yoshida, Mariko|Ota, Hajime|Onishi, Ichiro|Kayahara, Masato|Ohtsubo, Koushiro|Kagaya, Takashi|Honda, Masao|Kaneko, Shuichi | ||||||||||
| PMID: | 24633336 | ||||||||||
| 65. | |||||||||||
| Journal: | PLoS One. 2014 Apr 2;9(4):e92161. | ||||||||||
| Title: | Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. | ||||||||||
| Author: | Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 24694877 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer Lett. 2014 Aug 28;351(1):151-61. | ||||||||||
| Title: | XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W | ||||||||||
| PMID: | 24880079 | ||||||||||
| 67. | |||||||||||
| Journal: | Cancer Sci. 2014 Sep;105(9):1116-23. | ||||||||||
| Title: | Expression of platelet-derived growth factor receptor beta is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis. | ||||||||||
| Author: | Miyazaki, Hideki|Yoshimatsu, Yasuhiro|Akatsu, Yuichi|Mishima, Koichi|Fukayama, Masashi|Watabe, Tetsuro|Miyazono, Kohei | ||||||||||
| PMID: | 24981766 | ||||||||||
| 68. | |||||||||||
| Journal: | Cell Rep. 2014 Aug 7;8(3):696-706. | ||||||||||
| Title: | Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade. | ||||||||||
| Author: | Rigamonti, Nicolo|Kadioglu, Ece|Keklikoglou, Ioanna|Wyser Rmili, Celine|Leow, Ching Ching|De Palma, Michele | ||||||||||
| PMID: | 25088418 | ||||||||||
| 69. | |||||||||||
| Journal: | Pathol Res Pract. 2014 Dec;210(12):901-8. | ||||||||||
| Title: | Serous neoplasms of the pancreas share many, but not all aspects of their microvascular and angiogenic profile with low-grade clear cell renal cell carcinomas. | ||||||||||
| Author: | Liszka, Lukasz|Pajak, Jacek|Golka, Dariusz | ||||||||||
| PMID: | 25155377 | ||||||||||
| 70. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Oct 7;20(37):13343-68. | ||||||||||
| Title: | Gene therapy in pancreatic cancer. | ||||||||||
| Author: | Liu, Si-Xue|Xia, Zhong-Sheng|Zhong, Ying-Qiang | ||||||||||
| PMID: | 25309069 | ||||||||||
| 71. | |||||||||||
| Journal: | Radiology. 2015 Mar;274(3):790-9. | ||||||||||
| Title: | Vascular endothelial growth factor receptor type 2-targeted contrast-enhanced US of pancreatic cancer neovasculature in a genetically engineered mouse model: potential for earlier detection. | ||||||||||
| Author: | Pysz, Marybeth A|Machtaler, Steven B|Seeley, E Scott|Lee, John J|Brentnall, Teresa A|Rosenberg, Jarrett|Tranquart, Francois|Willmann, Jurgen K | ||||||||||
| PMID: | 25322341 | ||||||||||
| 72. | |||||||||||
| Journal: | Virchows Arch. 2015 Feb;466(2):237-41. | ||||||||||
| Title: | Basaloid carcinoma of the pancreas--clinicopathological presentation and oncogenetic snapshot of a rare entity. | ||||||||||
| Author: | Szasz, A Marcell|Szirtes, Ildiko|Tihanyi, Balazs|Barkaszi, Bernadett|Baranyai, Zsolt|Tihanyi, Tibor|Harsanyi, Laszlo|Timar, Jozsef|Kulka, Janina | ||||||||||
| PMID: | 25432630 | ||||||||||
| 73. | |||||||||||
| Journal: | Mol Cancer Ther. 2015 Feb;14(2):407-18. | ||||||||||
| Title: | A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer. | ||||||||||
| Author: | Pan, Youli|Zheng, Mingwu|Zhong, Lei|Yang, Jiao|Zhou, Shu|Qin, Ya|Xiang, Rong|Chen, Yuzong|Yang, Sheng-Yong | ||||||||||
| PMID: | 25519702 | ||||||||||
| 74. | |||||||||||
| Journal: | Oncotarget. 2015 Jun 20;6(17):14940-52. | ||||||||||
| Title: | Foretinib inhibits angiogenesis, lymphangiogenesis and tumor growth of pancreatic cancer in vivo by decreasing VEGFR-2/3 and TIE-2 signaling. | ||||||||||
| Author: | Chen, Hsiu-Mei|Tsai, Chia-Hua|Hung, Wen-Chun | ||||||||||
| PMID: | 25909285 | ||||||||||
| 75. | |||||||||||
| Journal: | Oncotarget. 2015 Jul 20;6(20):17981-8000. | ||||||||||
| Title: | Identification of TAX2 peptide as a new unpredicted anti-cancer agent. | ||||||||||
| Author: | Jeanne, Albin|Sick, Emilie|Devy, Jerome|Floquet, Nicolas|Belloy, Nicolas|Theret, Louis|Boulagnon-Rombi, Camille|Diebold, Marie-Daniele|Dauchez, Manuel|Martiny, Laurent|Schneider, Christophe|Dedieu, Stephane | ||||||||||
| PMID: | 26046793 | ||||||||||
| 76. | |||||||||||
| Journal: | Cancer Genet. 2015 Jul-Aug;208(7-8):374-81. | ||||||||||
| Title: | Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines. | ||||||||||
| Author: | Boora, Ganesh K|Kanwar, Rahul|Kulkarni, Amit A|Pleticha, Josef|Ames, Matthew|Schroth, Gary|Beutler, Andreas S|Banck, Michaela S | ||||||||||
| PMID: | 26087898 | ||||||||||
| 77. | |||||||||||
| Journal: | Oncoimmunology. 2015 Mar 16;4(4):e1001217. | ||||||||||
| Title: | Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial. | ||||||||||
| Author: | Schmitz-Winnenthal, Friedrich H|Hohmann, Nicolas|Niethammer, Andreas G|Friedrich, Tobias|Lubenau, Heinz|Springer, Marco|Breiner, Klaus M|Mikus, Gerd|Weitz, Jurgen|Ulrich, Alexis|Buechler, Markus W|Pianka, Frank|Klaiber, Ulla|Diener, Markus|Leowardi, Chris | ||||||||||
| PMID: | 26137397 | ||||||||||
| 78. | |||||||||||
| Journal: | Medicine (Baltimore). 2015 Aug;94(32):e1303. | ||||||||||
| Title: | An Attempt to Evaluate Selected Aspects of "Bone-Fat Axis" Function in Healthy Individuals and Patients With Pancreatic Cancer. | ||||||||||
| Author: | Blogowski, Wojciech|Dolegowska, Katarzyna|Deskur, Anna|Dolegowska, Barbara|Starzynska, Teresa | ||||||||||
| PMID: | 26266370 | ||||||||||
| 79. | |||||||||||
| Journal: | Clin Exp Metastasis. 2015 Dec;32(8):799-817. | ||||||||||
| Title: | Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors. | ||||||||||
| Author: | Moen, Ingrid|Gebre, Matthew|Alonso-Camino, Vanesa|Chen, Debbie|Epstein, David|McDonald, Donald M | ||||||||||
| PMID: | 26445848 | ||||||||||
| 80. | |||||||||||
| Journal: | Transl Oncogenomics. 2015 Nov 23;7(Suppl 1):13-31. | ||||||||||
| Title: | c-Met as a Target for Personalized Therapy. | ||||||||||
| Author: | Garajova, Ingrid|Giovannetti, Elisa|Biasco, Guido|Peters, Godefridus J | ||||||||||
| PMID: | 26628860 | ||||||||||
| 81. | |||||||||||
| Journal: | Rom J Intern Med. 2015 Jul-Sep;53(3):199-208. | ||||||||||
| Title: | VEGF Expression in Pancreatic Cancer and Other Malignancies: A Review of the Literature. | ||||||||||
| Author: | Costache, M I|Ioana, Mihai|Iordache, Sevastita|Ene, D|Costache, Cornelia Alexandra|Saftoiu, A | ||||||||||
| PMID: | 26710495 | ||||||||||
| 82. | |||||||||||
| Journal: | Anticancer Agents Med Chem. 2016;16(6):771-80. | ||||||||||
| Title: | Multiple Pharmacological Properties of a Novel Parthenin Analog P16 as Evident by its Cytostatic and Antiangiogenic Potential Against Pancreatic Adenocarcinoma PANC -1 Cells. | ||||||||||
| Author: | Goswami, Akshra|Shah, Bhahwal Ali|Batra, Navneet|Kumar, Ajay|Guru, Santosh Kumar|Bhushan, Shashi|Malik, Fayaz Ahmad|Joshi, Amit|Singh, Jagtar | ||||||||||
| PMID: | 26299660 | ||||||||||
| 83. | |||||||||||
| Journal: | Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38. | ||||||||||
| Title: | |||||||||||