Primary Site >> Stomach Cancer

Gene >> KDR

Journal: Clin Cancer Res. 1996 Oct;2(10):1679-84.
Title: Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer.
Author: Takahashi, Y|Cleary, K R|Mai, M|Kitadai, Y|Bucana, C D|Ellis, L M
PMID: 9816116
Journal: J Clin Oncol. 1997 Feb;15(2):826-32.
Title: Correlation between expression of vascular endothelial growth factor and tumor vascularity, and patient outcome in human gastric carcinoma.
Author: Tanigawa, N|Amaya, H|Matsumura, M|Shimomatsuya, T
PMID: 9053510
Journal: Surg Today. 1998;28(4):367-72.
Title: Angiogenesis in poorly differentiated medullary carcinoma of the stomach.
Author: Takahashi, Y|Ellis, L M|Ohta, T|Mai, M
PMID: 9590699
Journal: Chin Med J (Engl). 2000 Nov;113(11):1031-5.
Title: Lymphangiogenesis in tumor tissues and 5'-Nase, Flt-4, Flk-1 expressions.
Author: Liao, X|Tang, W|Cai, Q|Li, F|Fu, Z
PMID: 11776119
Journal: Eur J Cancer. 2001 May;37(7):918-23.
Title: Lymphangiogenesis and the vascular endothelial growth factor receptor (VEGFR)-3 in gastric cancer.
Author: Yonemura, Y|Fushida, S|Bando, E|Kinoshita, K|Miwa, K|Endo, Y|Sugiyama, K|Partanen, T|Yamamoto, H|Sasaki, T
PMID: 11313181
Journal: J Am Chem Soc. 2001 Nov 28;123(47):11586-93.
Title: Total synthesis and biological evaluation of the nakijiquinones.
Author: Stahl, P|Kissau, L|Mazitschek, R|Huwe, A|Furet, P|Giannis, A|Waldmann, H
PMID: 11716712
Journal: World J Gastroenterol. 2001 Aug;7(4):500-5.
Title: Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinoma.
Author: Liu, D H|Zhang, X Y|Fan, D M|Huang, Y X|Zhang, J S|Huang, W Q|Zhang, Y Q|Huang, Q S|Ma, W Y|Chai, Y B|Jin, M
PMID: 11819817
Journal: Cancer Gene Ther. 2002 Feb;9(2):197-201.
Title: VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice.
Author: Kamiyama, Masako|Ichikawa, Yasushi|Ishikawa, Takashi|Chishima, Takashi|Hasegawa, Satoshi|Hamaguchi, Yohei|Nagashima, Yoji|Miyagi, Yohei|Mitsuhashi, Masato|Hyndman, David|Hoffman, Robert M|Ohki, Shigeo|Shimada, Hiroshi
PMID: 11857038
Journal: World J Gastroenterol. 2002 Aug;8(4):596-601.
Title: The role of KDR in the interactions between human gastric carcinoma cell and vascular endothelial cell.
Author: Ren, Juan|Dong, Lei|Xu, Cang-Bao|Pan, Bo-Rong
PMID: 12174363
Journal: World J Gastroenterol. 2002 Dec;8(6):994-8.
Title: Expression of vascular endothelial growth factor and its receptors KDR and Flt-1 in gastric cancer cells.
Author: Zhang, Hua|Wu, Jian|Meng, Lin|Shou, Cheng-Chao
PMID: 12439912
Journal: Br J Cancer. 2003 Mar 10;88(5):796-802.
Title: Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells.
Author: Akagi, M|Kawaguchi, M|Liu, W|McCarty, M F|Takeda, A|Fan, F|Stoeltzing, O|Parikh, A A|Jung, Y D|Bucana, C D|Mansfield, P F|Hicklin, D J|Ellis, L M
PMID: 12618892
Journal: Zhonghua Yi Xue Za Zhi. 2003 May 10;83(9):782-6.
Title: [Expression of MMP-9 and MMP-9 mRNA in gastric carcinoma and its correlation with angiogenesis].
Author: Wang, Lu|Zhang, Li-hong|Li, Yu-lin|Li, Yi-lei|Liu, Zhan
PMID: 12899759
Journal: Int J Cancer. 2004 Aug 20;111(2):165-73.
Title: Suppression of tumor growth and metastasis by a VEGFR-1 antagonizing peptide identified from a phage display library.
Author: An, Ping|Lei, Hetian|Zhang, Jianzhi|Song, Shumei|He, Luowen|Jin, Genglin|Liu, Xiaoying|Wu, Jian|Meng, Lin|Liu, Meisheng|Shou, Chengchao
PMID: 15197767
Journal: Clin Cancer Res. 2004 Jul 1;10(13):4349-56.
Title: Depleted dopamine in gastric cancer tissues: dopamine treatment retards growth of gastric cancer by inhibiting angiogenesis.
Author: Chakroborty, Debanjan|Sarkar, Chandrani|Mitra, Rita Basu|Banerjee, Samir|Dasgupta, Partha Sarathi|Basu, Sujit
PMID: 15240521
Journal: Cancer Treat Rev. 2004 Aug;30(5):451-9.
Title: Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches.
Author: Scartozzi, Mario|Galizia, Eva|Freddari, Federica|Berardi, Rossana|Cellerino, Riccardo|Cascinu, Stefano
PMID: 15245777
Journal: Mol Cancer Ther. 2004 Sep;3(9):1041-8.
Title: ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer.
Author: McCarty, Marya F|Wey, Jane|Stoeltzing, Oliver|Liu, Wenbiao|Fan, Fan|Bucana, Corazon|Mansfield, Paul F|Ryan, Anderson J|Ellis, Lee M
PMID: 15367698
Journal:
Title: (64)Cu-1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid-quantum dot-vascular endothelial growth factor
Author: Zhang, Huiming
PMID: 20641777
Journal: World J Gastroenterol. 2005 Feb 21;11(7):938-42.
Title: Effect of Weikangning on gastric cancer cell growth and expression of vascular endothelial growth factor and its receptors KDR and Flt-1.
Author: Li, Qing-Ming|Kan, Fang-Ju|Min, Cun-Yun
PMID: 15742392
Journal: J Med Chem. 2005 Mar 10;48(5):1359-66.
Title: Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.
Author: Kubo, Kazuo|Shimizu, Toshiyuki|Ohyama, Shin-ichi|Murooka, Hideko|Iwai, Akemi|Nakamura, Kazuhide|Hasegawa, Kazumasa|Kobayashi, Yoshiko|Takahashi, Noriko|Takahashi, Kazumi|Kato, Shinichiro|Izawa, Toshio|Isoe, Toshiyuki
PMID: 15743179
Journal: Di Yi Jun Yi Da Xue Xue Bao. 2005 Aug;25(8):947-50.
Title: [Specific killing effects of adenovirus-mediated double suicide gene driven by KDR promoter on venous endothelial cells and gastric cancer cells in vitro].
Author: Huang, Zong-hai|Su, Guo-qiang|Yu, Jin-long|Li, Zhou|Fan, Ying-fang|Zhou, Guang-jun|Song, Hui-juan
PMID: 16109546
Journal: World J Surg. 2005 Dec;29(12):1600-7.
Title: Prognostic significance of vascular endothelial growth factor D in gastric carcinoma.
Author: Shida, Atsuo|Fujioka, Shuichi|Ishibashi, Yoshio|Kobayashi, Katsutoshi|Nimura, Hiroshi|Mitsumori, Norio|Suzuki, Yutaka|Kawakami, Makio|Urashima, Mitsuyoshi|Yanaga, Katsuhiko
PMID: 16311850
Journal: Mol Cancer Res. 2005 Nov;3(11):607-15.
Title: Nicotine induces cyclooxygenase-2 and vascular endothelial growth factor receptor-2 in association with tumor-associated invasion and angiogenesis in gastric cancer.
Author: Shin, Vivian Y|Wu, William K K|Chu, Kent-Man|Wong, Helen P S|Lam, Emily K Y|Tai, Emily K K|Koo, Marcel W L|Cho, Chi-Hin
PMID: 16317086
Journal: Int J Cancer. 2006 Jan 15;118(2):483-9.
Title: ZD6474 inhibits tumor growth and intraperitoneal dissemination in a highly metastatic orthotopic gastric cancer model.
Author: Arao, Tokuzo|Yanagihara, Kazuyoshi|Takigahira, Misato|Takeda, Masayuki|Koizumi, Fumiaki|Shiratori, Yasushi|Nishio, Kazuto
PMID: 16052530
Journal: Int J Clin Oncol. 2006 Feb;11(1):38-43.
Title: Expression of vascular endothelial growth factor (VEGF)-C and -D in gastric carcinoma.
Author: Shida, Atsuo|Fujioka, Shuichi|Kobayashi, Katsutoshi|Ishibashi, Yoshio|Nimura, Hiroshi|Mitsumori, Norio|Yanaga, Katsuhiko
PMID: 16508727
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2006 Apr;26(4):402-5.
Title: [In vitro killing effect of adenovirus-mediated fusion gene system driven by KDR promoter on gastric cancer cells].
Author: Zhou, Guang-jun|Huang, Zong-hai|Yu, Jin-long|Li, Zhou|Su, Guo-qiang
PMID: 16624737
Journal: J Exp Clin Cancer Res. 2006 Mar;25(1):83-8.
Title: The effects of VEGF and VEGFR-2 on survival in patients with gastric cancer.
Author: Ozdemir, F|Akdogan, R|Aydin, F|Reis, A|Kavgaci, H|Gul, S|Akdogan, E
PMID: 16761623
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Jun;26 Suppl:88-92.
Title: [Effects of weikangning contained serum on growth of gastric cancer cell, expression of vascular endothelial growth factor and its receptors including KDR and fit-1].
Author: Li, Qing-ming|Kan, Fang-ju|Min, Cun-yun
PMID: 17569358
Journal: World J Gastroenterol. 2007 Dec 28;13(48):6498-505.
Title: Effect of arsenic trioxide on vascular endothelial cell proliferation and expression of vascular endothelial growth factor receptors Flt-1 and KDR in gastric cancer in nude mice.
Author: Xiao, Yan-Feng|Wu, De-Dong|Liu, Shan-Xi|Chen, Xi|Ren, Li-Fen
PMID: 18161919
Journal: J Cancer Res Clin Oncol. 2008 Feb;134(2):153-61.
Title: Lymphatic and/or blood vessel invasion in gastric cancer: relationship with clinicopathological parameters, biological factors and prognostic significance.
Author: del Casar, Jose M|Corte, Maria D|Alvarez, Ana|Garcia, Isabel|Bongera, Miguel|Gonzalez, Luis O|Garcia-Muniz, Jose L|Allende, Maria T|Astudillo, Aurora|Vizoso, Francisco J
PMID: 17628829
Journal: Oncol Rep. 2008 Apr;19(4):939-44.
Title: Vascular endothelial growth factor receptor-3 is a favorable prognostic factor in advanced gastric carcinoma.
Author: Sung, Ji-Youn|Lee, Sun|Kim, Youn Wha|Park, Yong-Koo
PMID: 18357379
Journal: Life Sci. 2008 Apr 23;82(17-18):956-63.
Title: Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2.
Author: Lu, Na|Gao, Ying|Ling, Yun|Chen, Yan|Yang, Yong|Gu, Hong-Yan|Qi, Qi|Liu, Wei|Wang, Xiao-Tang|You, Qi-Dong|Guo, Qing-Long
PMID: 18378261
Journal: World J Gastroenterol. 2008 Jun 28;14(24):3879-83.
Title: Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma.
Author: Al-Moundhri, Mansour-S|Al-Shukaili, A|Al-Nabhani, M|Al-Bahrani, B|Burney, I-A|Rizivi, A|Ganguly, S-S
PMID: 18609713
Journal: J Korean Med Sci. 2008 Aug;23(4):592-7.
Title: Correlation of vascular endothelial growth factor-D expression and VEGFR-3-positive vessel density with lymph node metastasis in gastric carcinoma.
Author: Choi, Jung-Hye|Oh, Young-Ha|Park, Yong-Wook|Baik, Hong-Kyu|Lee, Young-Yiul|Kim, In-Soon
PMID: 18756043
Journal: Clin Cancer Res. 2008 Nov 15;14(22):7205-14.
Title: Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms.
Author: Kodama, Michiyo|Kitadai, Yasuhiko|Tanaka, Miwako|Kuwai, Toshio|Tanaka, Shinji|Oue, Naohide|Yasui, Wataru|Chayama, Kazuaki
PMID: 19010837
Journal: J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66.
Title: Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
Author: Arkenau, Hendrik-Tobias
PMID: 19363621
Journal: Folia Histochem Cytobiol. 2009;47(1):81-6.
Title: Soluble angiogenesis markers in gastric tumor patients.
Author: Mysliwiec, Piotr|Pawlak, Krystyna|Bandurski, Roman|Kedra, Boguslaw
PMID: 19419943
Journal: Expert Opin Investig Drugs. 2009 Jul;18(7):945-55.
Title: Novel investigational drugs for gastric cancer.
Author: Vecchione, Loredana|Orditura, Michele|Ciardiello, Fortunato|De Vita, Ferdinando
PMID: 19466878
Journal: Jpn J Clin Oncol. 2009 Sep;39(9):543-51.
Title: Anti-angiogenic therapy against gastrointestinal tract cancers.
Author: Iwasaki, Junko|Nihira, Shin-ichi
PMID: 19531544
Journal: Epigenetics. 2009 Jul 1;4(5):313-21. Epub 2009 Jul 3.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Hwang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 19633424
Journal: Surgery. 2009 Nov;146(5):896-905.
Title: Vascular endothelial growth factor-D is correlated with hepatic metastasis from gastric cancer after radical gastrectomy.
Author: Deng, Jingyu|Liang, Han|Sun, Dan|Pan, Yi|Wang, Baogui|Guo, Yuhong
PMID: 19744460
Journal: Epigenetics. 2009 Jul 1;4(5):313-321.
Title: The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.
Author: Kim, Jee Yeon|Whang, Jun Ha|Zhou, Wei|Shin, Jieun|Noh, Seung Moo|Song, In Sang|Kim, Ji Yeon|Lee, Suk Hoon|Kim, Jei
PMID: 28001118
Journal: Int J Cancer. 2010 Sep 1;127(5):1197-208.
Title: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways.
Author: Lyros, Orestis|Mueller, Annett|Heidel, Florian|Schimanski, Carl C|Gockel, Ines|Galle, Peter R|Lang, Hauke|Moehler, Markus
PMID: 20039326
Journal: Cancer Sci. 2010 Oct;101(10):2121-7.
Title: Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells.
Author: Tanaka, Miwako|Kitadai, Yasuhiko|Kodama, Michiyo|Shinagawa, Kei|Sumida, Tomonori|Tanaka, Shinji|Oue, Naohide|Yasui, Wataru|Chayama, Kazuaki
PMID: 20626397
Journal: Gan To Kagaku Ryoho. 2010 Aug;37(8):1489-96.
Title: [Impact of HER2, EGFR, IGF-1R, and VEGFR expressions on the outcome of chemotherapy for advanced gastric cancer].
Author: Matsubara, Junichi|Hirashima, Yoshinori|Yamada, Yasuhide
PMID: 20716873
Journal: J Exp Clin Cancer Res. 2011 Jan 25;30:13.
Title: The function and mechanism of COX-2 in angiogenesis of gastric cancer cells.
Author: Yao, Liping|Liu, Fei|Hong, Liu|Sun, Li|Liang, Shuhui|Wu, Kaichun|Fan, Daiming
PMID: 21266034
Journal: Oncol Rep. 2011 Jul;26(1):23-32.
Title: Aurora-A as an independent molecular prognostic marker in gastric cancer.
Author: Wang, Jing|Yang, Sheng|Zhang, Haizeng|Song, Yan|Zhang, Xun|Qian, Haili|Han, Xiaohong|Shi, Yuankai
PMID: 21479365
Journal: Structure. 2011 Aug 10;19(8):1097-107.
Title: The structural basis for the function of two anti-VEGF receptor 2 antibodies.
Author: Franklin, Matthew C|Navarro, Elizabeth C|Wang, Yujie|Patel, Sheetal|Singh, Pinki|Zhang, Yi|Persaud, Kris|Bari, Amtul|Griffith, Heather|Shen, Leyi|Balderes, Paul|Kussie, Paul
PMID: 21827946
Journal: Int J Oncol. 2012 Apr;40(4):1097-104.
Title: Stem cells with fused gene expression of cytosine deaminase and interferon-beta migrate to human gastric cancer cells and result in synergistic growth inhibition for potential therapeutic use.
Author: Kim, Kyoung-Yoon|Yi, Bo-Rim|Lee, Hye-Rim|Kang, Nam-Hee|Jeung, Eui-Bae|Kim, Seung U|Choi, Kyung-Chul
PMID: 22159640
Journal: BMC Cancer. 2012 Jan 25;12:37.
Title: Biomarkers for antitumor activity of bevacizumab in gastric cancer models.
Author: Yamashita-Kashima, Yoriko|Fujimoto-Ouchi, Kaori|Yorozu, Keigo|Kurasawa, Mitsue|Yanagisawa, Mieko|Yasuno, Hideyuki|Mori, Kazushige
PMID: 22273502
Journal: Gut. 2012 May;61(5):673-84.
Title: A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets.
Author: Deng, Niantao|Goh, Liang Kee|Wang, Hannah|Das, Kakoli|Tao, Jiong|Tan, Iain Beehuat|Zhang, Shenli|Lee, Minghui|Wu, Jeanie|Lim, Kiat Hon|Lei, Zhengdeng|Goh, Glenn|Lim, Qing-Yan|Tan, Angie Lay-Keng|Sin Poh, Dianne Yu|Riahi, Sudep|Bell, Sandra|Shi, Michael M|
PMID: 22315472
Journal: Int Immunopharmacol. 2012 May;13(1):37-45.
Title: Ad-KDRscFv:sTRAIL displays a synergistic antitumor effect without obvious cytotoxicity to normal tissues.
Author: Yang, Liuqin|Guo, Jun|Wang, Jun|Wan, Shunmei|Yang, Shiming|Wang, Rongquan|Chen, Wensheng|Peng, Guiyong|Fang, Dianchun
PMID: 22406047
Journal: Expert Opin Ther Targets. 2012 Apr;16 Suppl 2:S29-34.
Title: Current status of targeted therapies in advanced gastric cancer.
Author: De Vita, Ferdinando|Giuliani, Francesco|Silvestris, Nicola|Rossetti, Sabrina|Pizzolorusso, Antonio|Santabarbara, Giuseppe|Galizia, Gennaro|Colucci, Giuseppe|Ciardiello, Fortunato|Orditura, Michele
PMID: 22443228
Journal: Chin J Integr Med. 2012 May;18(5):350-8.
Title: Tumor interstitial fluid and gastric cancer metastasis: an experimental study to verify the hypothesis of "tumor-phlegm microenvironment".
Author: Sun, Da-zhi|Jiao, Jian-peng|Ju, Da-wei|Ye, Min|Zhang, Xuan|Xu, Jing-yu|Lu, Ye|He, Jin|Wei, Pin-kang|Yang, Ming-hui
PMID: 22549391
Journal: J Clin Oncol. 2012 Jun 10;30(17):2119-27.
Title: Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a biomarker evaluation from the AVAGAST randomized phase III trial.
Author: Van Cutsem, Eric|de Haas, Sanne|Kang, Yoon-Koo|Ohtsu, Atsushi|Tebbutt, Niall C|Ming Xu, Jian|Peng Yong, Wei|Langer, Bernd|Delmar, Paul|Scherer, Stefan J|Shah, Manish A
PMID: 22565005
Journal: PLoS One. 2012;7(7):e38192.
Title: Role of vascular endothelial growth factor (VEGF) and VEGF-R genotyping in guiding the metastatic process in pT4a resected gastric cancer patients.
Author: Scartozzi, Mario|Loretelli, Cristian|Galizia, Eva|Mandolesi, Alessandra|Pistelli, Mirco|Bittoni, Alessandro|Giampieri, Riccardo|Faloppi, Luca|Bianconi, Maristella|Del Prete, Michela|Bianchi, Francesca|Belvederesi, Laura|Bearzi, Italo|Cascinu, Stefano
PMID: 22808003
Journal: Int J Oncol. 2012 Oct;41(4):1297-304.
Title: Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
Author: Masuzawa, Toru|Fujiwara, Yoshiyuki|Okada, Kaoru|Nakamura, Ayumu|Takiguchi, Shuji|Nakajima, Kiyokazu|Miyata, Hiroshi|Yamasaki, Makoto|Kurokawa, Yukinori|Osawa, Ryuji|Takeda, Kazuyoshi|Yoshida, Koji|Tsunoda, Takuya|Nakamura, Yusuke|Mori, Masaki|Doki, Yuichi
PMID: 22842485
Journal: Clin Transl Oncol. 2013 Apr;15(4):265-70.
Title: Serum VEGF and VEGF-C values before surgery and after postoperative treatment in gastric cancer.
Author: Villarejo-Campos, Pedro|Padilla-Valverde, David|Martin, Raul Martin|Menendez-Sanchez, Pablo|Cubo-Cintas, Teofilo|Bondia-Navarro, Jose Antonio|Fernandez, Jesus Martin
PMID: 22855190
Journal: Yonsei Med J. 2013 Mar 1;54(2):374-80.
Title: Blockade of VEGFR-1 and VEGFR-2 enhances paclitaxel sensitivity in gastric cancer cells.
Author: Hwang, Jun-Eul|Lee, Ji-Hee|Park, Mi-Ra|Kim, Dae-Eun|Bae, Woo-Kyun|Shim, Hyun-Jeong|Cho, Sang-Hee|Chung, Ik-Joo
PMID: 23364970
Journal: PLoS One. 2013;8(3):e54014.
Title: Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer.
Author: Shah, Manish A|Wainberg, Zev A|Catenacci, Daniel V T|Hochster, Howard S|Ford, James|Kunz, Pamela|Lee, Fa-Chyi|Kallender, Howard|Cecchi, Fabiola|Rabe, Daniel C|Keer, Harold|Martin, Anne-Marie|Liu, Yuan|Gagnon, Robert|Bonate, Peter|Liu, Li|Gilmer, Tona|Bott
PMID: 23516391
Journal: Mol Cancer Ther. 2013 Jun;12(6):913-24.
Title: A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.
Author: Awazu, Yoshiko|Nakamura, Kazuhide|Mizutani, Akio|Kakoi, Yuichi|Iwata, Hidehisa|Yamasaki, Seiji|Miyamoto, Naoki|Imamura, Shinichi|Miki, Hiroshi|Hori, Akira
PMID: 23548264
Journal: Cell Biochem Biophys. 2013;67(3):1021-7.
Title: Study of the mechanism of bystander effect of KDR-CDglyTK system mediated by adenovirus for the treatment of gastric cancer.
Author: Qiang, Li|Yanping, Li|Zonghai, Huang|Fei, Chen|Zhou, Li|Jinlong, Yu
PMID: 23605100
Journal: Future Oncol. 2013 Jun;9(6):789-95.
Title: Ramucirumab: a novel antiangiogenic agent.
Author: Wadhwa, Roopma|Taketa, Takashi|Sudo, Kazuki|Blum-Murphy, Mariela|Ajani, Jaffer A
PMID: 23718298
Journal: PLoS One. 2013 Jun 5;8(6):e65264.
Title: Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways.
Author: Zhang, Chao|Wu, Xihan|Zhang, Meifang|Zhu, Liangcheng|Zhao, Rong|Xu, Danqing|Lin, Zhaohu|Liang, Chungen|Chen, Taiping|Chen, Li|Ren, Yi|Zhang, Joe|Qin, Ning|Zhang, Xiongwen
PMID: 23755206
Journal: Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Title: S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Author: Burbridge, Mike F|Bossard, Celine J|Saunier, Carine|Fejes, Imre|Bruno, Alain|Leonce, Stephane|Ferry, Gilles|Da Violante, Georges|Bouzom, Francois|Cattan, Valerie|Jacquet-Bescond, Anne|Comoglio, Paolo M|Lockhart, Brian P|Boutin, Jean A|Cordi, Alex|Ortuno,
PMID: 23804704
Journal: J Cancer Res Clin Oncol. 2013 Dec;139(12):2057-70.
Title: siRNA-participated chemotherapy: an efficient and specific therapeutic against gastric cancer.
Author: Zhou, Donglei|Jiang, Xun|Ding, Weixing|Zheng, Lijun|Yang, Lei|Zheng, Chengzhu|Lu, Liesheng
PMID: 24077839
Journal: Pharmacogenomics. 2013 Dec;14(16):1991-8.
Title: Tumor angiogenesis genotyping and efficacy of first-line chemotherapy in metastatic gastric cancer patients.
Author: Scartozzi, Mario|Giampieri, Riccardo|Loretelli, Cristian|Bittoni, Alessandro|Mandolesi, Alessandra|Faloppi, Luca|Bianconi, Maristella|Del Prete, Michela|Andrikou, Kalliopi|Bearzi, Italo|Cascinu, Stefano
PMID: 24090479
Journal: Mol Cancer Ther. 2013 Dec;12(12):2748-59.
Title: A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent antitumor activity.
Author: Choi, Hye-Ji|Kim, Ye-Jin|Lee, Sangho|Kim, Yong-Sung
PMID: 24132142
Journal: Biomed Rep. 2013 May;1(3):399-404.
Title: Type II cGMP-dependent protein kinase inhibits activation of key members of the RTK family in gastric cancer cells.
Author: Jiang, Lu|Chen, Yongchang|Sang, Jianrong|Li, Yueying|Lan, Ting|Wang, Ying|Tao, Yan|Qian, Hai
PMID: 24648957
Journal: Lancet. 2014 Jan 4;383(9911):31-9.
Title: Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial.
Author: Fuchs, Charles S|Tomasek, Jiri|Yong, Cho Jae|Dumitru, Filip|Passalacqua, Rodolfo|Goswami, Chanchal|Safran, Howard|dos Santos, Lucas Vieira|Aprile, Giuseppe|Ferry, David R|Melichar, Bohuslav|Tehfe, Mustapha|Topuzov, Eldar|Zalcberg, John Raymond|Chau, Ian|C
PMID: 24094768
Journal: Expert Rev Anticancer Ther. 2014 Apr;14(4):367-79.
Title: Anti-angiogenic agent ramucirumab: meaningful or marginal?
Author: Wadhwa, Roopma|Elimova, Elena|Shiozaki, Hironori|Sudo, Kazuki|Blum, Mariela A|Estrella, Jeannelyn S|Chen, Qiongrong|Song, Shumei|Ajani, Jaffer A
PMID: 24605771
Journal: Oncol Rep. 2014 May;31(5):2312-20.
Title: SPARC expression is negatively correlated with clinicopathological factors of gastric cancer and inhibits malignancy of gastric cancer cells.
Author: Zhang, Junling|Wang, Pengyuan|Zhu, Jing|Wang, Wei|Yin, Jie|Zhang, Chi|Chen, Ziyi|Sun, Lie|Wan, Yuanlian|Wang, Xin|Chen, Guowei|Liu, Yucun
PMID: 24676680
Journal: World J Gastroenterol. 2014 Apr 14;20(14):3927-37.
Title: An updated review of gastric cancer in the next-generation sequencing era: insights from bench to bedside and vice versa.
Author: Yamamoto, Hiroyuki|Watanabe, Yoshiyuki|Maehata, Tadateru|Morita, Ryo|Yoshida, Yoshihito|Oikawa, Ritsuko|Ishigooka, Shinya|Ozawa, Shun-Ichiro|Matsuo, Yasumasa|Hosoya, Kosuke|Yamashita, Masaki|Taniguchi, Hiroaki|Nosho, Katsuhiko|Suzuki, Hiromu|Yasuda, Hiros
PMID: 24744582
Journal: Drugs. 2014 Jun;74(9):1047-58.
Title: Ramucirumab: first global approval.
Author: Poole, Raewyn M|Vaidya, Asha
PMID: 24916147
Journal: Future Oncol. 2014;10(9):1549-57.
Title: Ramucirumab for metastatic gastric or gastroesophageal junction cancer: results and implications of the REGARD trial.
Author: Liguigli, Wanda|Tomasello, Gianluca|Toppo, Laura|Ratti, Margherita|Passalacqua, Rodolfo
PMID: 25145426
Journal: Lancet Oncol. 2014 Oct;15(11):1224-35.
Title: Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial.
Author: Wilke, Hansjochen|Muro, Kei|Van Cutsem, Eric|Oh, Sang-Cheul|Bodoky, Gyorgy|Shimada, Yasuhiro|Hironaka, Shuichi|Sugimoto, Naotoshi|Lipatov, Oleg|Kim, Tae-You|Cunningham, David|Rougier, Philippe|Komatsu, Yoshito|Ajani, Jaffer|Emig, Michael|Carlesi, Roberto|
PMID: 25240821
Journal: Mol Cancer Ther. 2014 Nov;13(11):2527-36.
Title: Pazopanib, a novel multitargeted kinase inhibitor, shows potent in vitro antitumor activity in gastric cancer cell lines with FGFR2 amplification.
Author: Kim, Seung Tae|Jang, Hye-Lim|Lee, Su Jin|Lee, Jeeyun|Choi, Yoon-La|Kim, Kyoung-Mee|Cho, Jeonghee|Park, Se Hoon|Park, Young Suk|Lim, Ho Yeong|Yashiro, Masakazu|Kang, Won Ki|Park, Joon Oh
PMID: 25249557
Journal: Crit Rev Oncol Hematol. 2015 Jan;93(1):18-27.
Title: Targeting vascular endothelial growth factor (VEGF) pathway in gastric cancer: preclinical and clinical aspects.
Author: Abdel-Rahman, Omar
PMID: 24970311
Journal: APMIS. 2015 May;123(5):365-72.
Title: Targeted therapy in gastric cancer.
Author: Thiel, Alexandra|Ristimaki, Ari
PMID: 25706252
Journal: Crit Rev Oncol Hematol. 2015 Aug;95(2):165-78.
Title: Angiogenic inhibitors in gastric cancers and gastroesophageal junction carcinomas: A critical insight.
Author: Aprile, Giuseppe|Ongaro, Elena|Del Re, Marzia|Lutrino, Stefania Eufemia|Bonotto, Marta|Ferrari, Laura|Rihawi, Karim|Cardellino, Giovanni Gerardo|Pella, Nicoletta|Danesi, Romano|Fasola, Gianpiero
PMID: 25800976
Journal: BMC Cancer. 2015 Feb 21;15:80.
Title: Gastric cancer-associated enhancement of von Willebrand factor is regulated by vascular endothelial growth factor and related to disease severity.
Author: Yang, Xia|Sun, Hai-jian|Li, Zhi-rong|Zhang, Hao|Yang, Wei-jun|Ni, Bing|Wu, Yu-zhang
PMID: 25886574
Journal: Asian Pac J Trop Med. 2015 Apr;8(4):319-24.
Title: Effects of gene silencing of CypB on gastric cancer cells.
Author: Guo, Feng|Zhang, Ying|Zhao, Chun-Na|Li, Lin|Guo, Yan-Jun
PMID: 25975506
Journal: Drugs Today (Barc). 2015 Apr;51(4):223-9.
Title: Apatinib: a promising oral antiangiogenic agent in the treatment of multiple solid tumors.
Author: Scott, A J|Messersmith, W A|Jimeno, A
PMID: 26020064
Journal: Expert Opin Emerg Drugs. 2015 Sep;20(3):479-93.
Title: Emerging kinase inhibitors of the treatment of gastric cancer.
Author: Vincenzi, Bruno|Imperatori, Marco|Silletta, Marianna|Marrucci, Eleonora|Santini, Daniele|Tonini, Giuseppe
PMID: 26021342
Journal: Expert Opin Biol Ther. 2015;15(9):1359-70.
Title: The coming of ramucirumab in the landscape of anti-angiogenic drugs: potential clinical and translational perspectives.
Author: Calvetti, Lorenzo|Pilotto, Sara|Carbognin, Luisa|Ferrara, Roberto|Caccese, Mario|Tortora, Giampaolo|Bria, Emilio
PMID: 26190526
Journal: Dtsch Med Wochenschr. 2015 Aug;140(16):1202-5.
Title: [Current standards in the treatment of gastric cancer].
Author: Hacker, Ulrich|Lordick, Florian
PMID: 26261926
Journal: Am J Transl Res. 2015 Aug 15;7(8):1429-39. eCollection 2015.
Title: Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes.
Author: Li, Shu-Chun|Ma, Rong|Wu, Jian-Zhong|Xiao, Xia|Wu, Wei|Li, Gang|Chen, Bo|Sharma, Ashok|Bai, Shan|Dun, Bo-Ying|She, Jin-Xiong|Tang, Jin-Hai
PMID: 26396673
Journal: Biologics. 2015 Sep 22;9:93-105.
Title: Clinical utility of ramucirumab in advanced gastric cancer.
Author: Chan, Matthew Mk|Sjoquist, Katrin M|Zalcberg, John R
PMID: 26451083
Journal: J Exp Clin Cancer Res. 2015 Oct 29;34:132.
Title: Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer.
Author: Huynh, Hung|Ong, Richard|Zopf, Dieter
PMID: 26514182
Journal: Am J Cancer Res. 2015 Oct 15;5(11):3376-88. eCollection 2015.
Title: The distinct signatures of VEGF and soluble VEGFR2 increase prognostic implication in gastric cancer.
Author: Ock, Chan-Young|Nam, Ah-Rong|Bang, Ju-Hee|Kim, Tae-Yong|Lee, Kyung-Hun|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Bang, Yung-Jue|Oh, Do-Youn
PMID: 26807318
Journal: Curr Drug Targets. 2016;17(15):1818-1826.
Title: Gastric Carcinoma at the Era of Targeted Therapies.
Author: Dreanic, Johann|Dhooge, Marion|Sion, Elena|Brezault, Catherine|Chaussade, Stanislas|Coriat, Romain
PMID: 25944013
Journal: Tumour Biol. 2016 Feb;37(2):1889-99.
Title: Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expression.
Author: Tang, Dong|Gao, Jun|Wang, Sen|Ye, Nianyuan|Chong, Yang|Huang, Yuqin|Wang, Jie|Li, Bin|Yin, Wei|Wang, Daorong
PMID: 26323258
Journal: Crit Rev Oncol Hematol. 2016 Mar;99:1-12.
Title: Systemic therapy beyond first-line in advanced gastric cancer: An overview of the main randomized clinical trials.
Author: Galdy, Salvatore|Cella, Chiara Alessandra|Spada, Francesca|Murgioni, Sabina|Frezza, Anna Maria|Ravenda, Simona Paola|Zampino, Maria Giulia|Fazio, Nicola
PMID: 26697987
Journal: Oncol Rep. 2016 Mar;35(3):1245-54.
Title: Targeted therapy for gastric cancer: Current status and future directions (Review).
Author: Yuan, Dan-Dan|Zhu, Zhong-Xiu|Zhang, Xia|Liu, Jie
PMID: 26718131
Journal: Tumour Biol. 2016 Jul;37(7):9221-32.
Title: DCT015, a new sorafenib derivate, inhibits tumor growth and angiogenesis in gastric cancer models.
Author: Wang, Wenyan|Wang, Hui|Ni, Yingying|Yao, Zhenming|Ye, Liang|Tian, Jingwei
PMID: 26768619
Journal: J Exp Clin Cancer Res. 2016 Jan 22;35:16.
Title: Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors.
Author: Li, Linhao|Jiang, Xian|Zhang, Qian|Dong, Xuesong|Gao, Yuqiang|He, Yuanlong|Qiao, Haiquan|Xie, Fangyu|Xie, Xiangjun|Sun, Xueying
PMID: 26795388
Journal: Cancer Lett. 2016 Mar 28;372(2):187-91.
Title: Apatinib: A novel receptor tyrosine kinase inhibitor for the treatment of gastric cancer.
Author: Roviello, Giandomenico|Ravelli, Andrea|Polom, Karol|Petrioli, Roberto|Marano, Luigi|Marrelli, Daniele|Roviello, Franco|Generali, Daniele
PMID: 26797419
Journal: Gastroenterol Res Pract. 2016;2016:4105615.
Title: Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application.
Author: Li, Kaichun|Li, Jin
PMID: 26880889
Journal: Target Oncol. 2016 Aug;11(4):479-87.
Title: Ramucirumab Clinical Development: an Emerging Role in Gastrointestinal Tumors.
Author: Sanchez-Gastaldo, Amparo|Gonzalez-Exposito, Reyes|Garcia-Carbonero, Rocio
PMID: 26887374
Journal: Oncol Lett. 2016 Feb;11(2):1043-1050.
Title: Interleukin-8: A potent promoter of angiogenesis in gastric cancer.
Author: Shi, Jun|Wei, Pin-Kang
PMID: 26893688
Journal: Nat Rev Clin Oncol. 2016 Jun;13(6):348-60.
Title: Clinical impact of tumour biology in the management of gastroesophageal cancer.
Author: Lordick, Florian|Janjigian, Yelena Y
PMID: 26925958
Journal: J Cancer Res Clin Oncol. 2016 Jun;142(6):1231-7.
Title: Value of FGFR2 expression for advanced gastric cancer patients receiving pazopanib plus CapeOX (capecitabine and oxaliplatin).
Author: Kim, Seung Tae|Ahn, Soomin|Lee, Jeeyun|Lee, Su Jin|Park, Se Hoon|Park, Young Suk|Lim, Ho Yeong|Kang, Won Ki|Kim, Kyoung-Mee|Park, Joon Oh
PMID: 26983912
Journal: Clin Cancer Res. 2016 Jul 15;22(14):3683-94.
Title: Pharmacodynamic Response of the MET/HGF Receptor to Small-Molecule Tyrosine Kinase Inhibitors Examined with Validated, Fit-for-Clinic Immunoassays.
Author: Srivastava, Apurva K|Hollingshead, Melinda G|Weiner, Jennifer|Navas, Tony|Evrard, Yvonne A|Khin, Sonny A|Ji, Jiuping Jay|Zhang, Yiping|Borgel, Suzanne|Pfister, Thomas D|Kinders, Robert J|Bottaro, Donald P|Linehan, W Marston|Tomaszewski, Joseph E|Doroshow,
PMID: 27001313
Journal: MAbs. 2016 Jul;8(5):892-904.
Title: Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis.
Author: Lee, Dongheon|Kim, Dongin|Choi, Yu Bin|Kang, Kyungjae|Sung, Eun-Sil|Ahn, Jin-Hyung|Goo, Junseo|Yeom, Dong-Hoon|Jang, Hyun Sook|Moon, Kyung Duk|Lee, Sang Hoon|You, Weon-Kyoo
PMID: 27049350
Journal: Oncotarget. 2016 May 3;7(18):26580-92.
Title: Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis.
Author: Li, Tao|Liu, Xiaoxia|Shen, Qin|Yang, Wenjun|Huo, Zhenghao|Liu, Qilun|Jiao, Haiyan|Chen, Jing
PMID: 27058891
Journal: Oncoimmunology. 2015 Oct 29;5(4):e1099798.
Title: Peripheral trafficking of bone-marrow-derived stem cells in patients with different types of gastric neoplasms.
Author: Blogowski, Wojciech|Zuba-Surma, Ewa|Salata, Daria|Budkowska, Marta|Dolegowska, Barbara|Starzynska, Teresa
PMID: 27141380
Journal: Expert Rev Clin Pharmacol. 2016 Jul;9(7):877-85.
Title: Ramucirumab for the treatment of gastric cancers, colorectal adenocarcinomas, and other gastrointestinal malignancies.
Author: Aprile, Giuseppe|Ferrari, Laura|Cremolini, Chiara|Bergamo, Francesca|Fontanella, Caterina|Battaglin, Francesca|Rihawi, Karim|Lonardi, Sara|Loupakis, Fotios|Scartozzi, Mario
PMID: 27149032
Journal: Dig Liver Dis. 2016 Sep;48(9):984-94.
Title: Recent insights in the therapeutic management of patients with gastric cancer.
Author: de Mestier, Louis|Lardiere-Deguelte, Sophie|Volet, Julien|Kianmanesh, Reza|Bouche, Olivier
PMID: 27156069
Journal: Lancet. 2016 Nov 26;388(10060):2654-2664.
Title: Gastric cancer.
Author: Van Cutsem, Eric|Sagaert, Xavier|Topal, Baki|Haustermans, Karin|Prenen, Hans
PMID: 27156933
Journal: Cancer Res. 2016 May 1;76(9):2573-86.
Title: Stromal-Based Signatures for the Classification of Gastric Cancer.
Author: Uhlik, Mark T|Liu, Jiangang|Falcon, Beverly L|Iyer, Seema|Stewart, Julie|Celikkaya, Hilal|O'Mahony, Marguerita|Sevinsky, Christopher|Lowes, Christina|Douglass, Larry|Jeffries, Cynthia|Bodenmiller, Diane|Chintharlapalli, Sudhakar|Fischl, Anthony|Gerald, Da
PMID: 27197264
Journal: Curr Oncol Rep. 2016 Jul;18(7):41.
Title: Personalised Treatment in Gastric Cancer: Myth or Reality?
Author: Tarazona, Noelia|Gambardella, Valentina|Huerta, Marisol|Rosello, Susana|Cervantes, Andres
PMID: 27215435
Journal: J Ethnopharmacol. 2016 Aug 2;189:230-7.
Title: Xiaotan Sanjie decoction inhibits angiogenesis in gastric cancer through Interleukin-8-linked regulation of the vascular endothelial growth factor pathway.
Author: Shi, Jun|Lu, Ye|Wei, Pinkang
PMID: 27224240
Journal: World J Gastroenterol. 2016 Jun 21;22(23):5422-9.
Title: Endocan-expressing microvessel density as a prognostic factor for survival in human gastric cancer.
Author: Chang, Yuan|Niu, Wei|Lian, Pei-Long|Wang, Xian-Qiang|Meng, Zhi-Xin|Liu, Yi|Zhao, Rui
PMID: 27340359
Journal: J Cancer Res Ther. 2016 Apr-Jun;12(2):775-81.
Title: Incidence and risk of hypertension associated with ramucirumab in cancer patients: A systematic review and meta-analysis.
Author: Qi, Wei-Xiang|Fu, Shen|Zhang, Qing|Guo, Xiao-Mao
PMID: 27461650
Journal: J Biol Chem. 2016 Sep 30;291(40):20891-20899.
Title: The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer.
Author: Watanabe, Kenta|Hirata, Michiko|Tominari, Tsukasa|Matsumoto, Chiho|Fujita, Hidenori|Yonekura, Kazuhiko|Murphy, Gillian|Nagase, Hideaki|Miyaura, Chisato|Inada, Masaki
PMID: 27539855
Journal: Expert Rev Anticancer Ther. 2016 Oct;16(10):1005-10.
Title: The safety and efficacy of ramucirumab in combination with paclitaxel for the treatment of advanced gastric or gastro-esophageal junction adenocarcinoma.
Author: Garrido, Marcelo
PMID: 27582051
Journal: Br J Cancer. 2016 Oct 11;115(8):974-982.
Title: Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab.
Author: Fuchs, Charles S|Tabernero, Josep|Tomasek, Jiri|Chau, Ian|Melichar, Bohuslav|Safran, Howard|Tehfe, Mustapha A|Filip, Dumitru|Topuzov, Eldar|Schlittler, Luis|Udrea, Anghel Adrian|Campbell, William|Brincat, Stephen|Emig, Michael|Melemed, Symantha A|Hozak, R
PMID: 27623234
Journal: Oncol Rep. 2016 Dec;36(6):3635-3642.
Title: Effect of colorectal cancer on the number of normal stem cells circulating in peripheral blood.
Author: Marlicz, Wojciech|Sielatycka, Katarzyna|Serwin, Karol|Kubis, Ewa|Tkacz, Marta|Gluszko, Rafal|Bialek, Andrzej|Starzynska, Teresa|Ratajczak, Mariusz Z
PMID: 27779706
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Oct 25;19(10):1191-1196.
Title: [Research status quo and progression in targeted therapy for advanced gastric cancer].
Author: Feng, Rui|Zhang, Xiaotian|Yang, Sheng
PMID: 27781258
Journal: Oncol Lett. 2016 Nov;12(5):3967-3974.
Title: Expression of semaphorin 6D and its receptor plexin-A1 in gastric cancer and their association with tumor angiogenesis.
Author: Lu, Yanjie|Xu, Qian|Chen, Lei|Zuo, Yanzhen|Liu, Shaochen|Hu, Yatao|Li, Xiaoru|Li, Yuhong|Zhao, Xiangyang
PMID: 27895757
Journal: Am J Transl Res. 2016 Dec 15;8(12):5729-5740. eCollection 2016.
Title: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers.
Author: Wu, Jianzhong|Li, Shuchun|Ma, Rong|Sharma, Ashok|Bai, Shan|Dun, Boying|Cao, Haixia|Jing, Changwen|She, Jinxiong|Feng, Jifeng
PMID: 28078044
Journal: Oncotarget. 2017 Feb 14;8(7):11990-12002.
Title: Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer.
Author: Lin, Yi|Zhai, Ertao|Liao, Bing|Xu, Lixia|Zhang, Xinhua|Peng, Sui|He, Yulong|Cai, Shirong|Zeng, Zhirong|Chen, Minhu
PMID: 28061477
Journal: Onco Targets Ther. 2017 Jan 18;10:447-452.
Title: Apatinib as post second-line therapy in EGFR wild-type and ALK-negative advanced lung adenocarcinoma.
Author: Fang, Shen-Cun|Zhang, Hai-Tao|Zhang, Ying-Ming|Xie, Wei-Ping
PMID: 28176910
Journal: Pathologe. 2017 Mar;38(2):87-92.
Title: [Novel pharmaceutical treatment approaches for gastric cancer].
Author: Lordick, F
PMID: 28220199
Journal: J Ethnopharmacol. 2017 May 5;203:1-10.
Title: Anticancer and anti-angiogenic activities of extract from Actinidia eriantha Benth root.
Author: Wu, Jian-Guo|Ma, Li|Lin, Shui-Hua|Wu, Yan-Bin|Yi, Jun|Yang, Bin-Jun|Wu, Jin-Zhong|Wong, Ka-Hing
PMID: 28323051
Journal: Oncotarget. 2017 Jul 18;8(29):48253-48262.
Title: Efficacy and safety of different molecular targeted agents based on chemotherapy for gastric cancer patients treatment: a network meta-analysis.
Author: Ren, Zheng|Sun, Jinping|Sun, Xinfang|Hou, Hongtao|Li, Ke|Ge, Quanxing
PMID: 28477027
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: J Gastrointest Oncol. 2017 Jun;8(3):418-429.
Title: Biologic therapy in esophageal and gastric malignancies: current therapies and future directions.
Author: Samson, Pamela|Lockhart, A Craig
PMID: 28736629
Journal: Expert Opin Investig Drugs. 2017 Sep;26(9):1007-1017.
Title: Angiogenesis inhibitors in early development for gastric cancer.
Author: Pinto, Mauricio P|Owen, Gareth I|Retamal, Ignacio|Garrido, Marcelo
PMID: 28770623
Journal: Onco Targets Ther. 2017 Aug 28;10:4269-4272.
Title: Apatinib in the treatment of advanced lung adenocarcinoma with KRAS mutation.
Author: Zeng, Da-Xiong|Wang, Chang-Guo|Huang, Jian-An|Jiang, Jun-Hong
PMID: 28894382
Journal: Oncotarget. 2017 Jan 26;8(34):57654-57669.
Title: Targeted therapies for gastric cancer: failures and hopes from clinical trials.
Author: Apicella, Maria|Corso, Simona|Giordano, Silvia
PMID: 28915702
Journal: Oncotarget. 2017 Aug 3;8(39):66248-66253.
Title: Efficiency of low dosage apatinib in post-first-line treatment of advanced lung adenocarcinoma.
Author: Zeng, Da-Xiong|Wang, Chang-Guo|Lei, Wei|Huang, Jian-An|Jiang, Jun-Hong
PMID: 29029508
Journal: Adv Exp Med Biol. 2017;1018:207-224.
Title: Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways.
Author: Yang, Xiaowen|Cheng, Zhijun|Zhang, Lihua|Wu, Guiru|Shi, Run|Gao, Zhenxing|Li, Chaoyang
PMID: 29052140
Journal: Surg Case Rep. 2017 Dec 19;3(1):127.
Title: A case of ramucirumab-related gastrointestinal perforation in gastric cancer with small bowel metastasis.
Author: Urakawa, Shinya|Sakai, Daisuke|Miyazaki, Yasuhiro|Kudo, Toshihiro|Katou, Aya|Inagaki, Chiaki|Tanaka, Koji|Makino, Tomoki|Takahashi, Tsuyoshi|Kurokawa, Yukinori|Yamasaki, Makoto|Nakajima, Kiyokazu|Takiguchi, Shuji|Satoh, Taroh|Mori, Masaki|Doki, Yuichiro
PMID: 29260338
Journal: BMC Cancer. 2017 Dec 20;17(1):875.
Title: Isoprenaline/beta2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis.
Author: Lu, Yanjie|Xu, Qian|Zuo, Yanzhen|Liu, Lei|Liu, Shaochen|Chen, Lei|Wang, Kang|Lei, Yuntao|Zhao, Xiangyang|Li, Yuhong
PMID: 29262812
Journal: NPJ Precis Oncol. 2017 May 1;1(1):9.
Title: Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival.
Author: Leong, Siew Hong|Lwin, Kyaw Myo|Lee, Sze Sing|Ng, Wai Har|Ng, Kia Min|Tan, Soo Yong|Ng, Bee Ling|Carter, Nigel P|Tang, Carol|Lian Kon, Oi
PMID: 29872697
Journal: Acta Pharmacol Sin. 2018 Feb;39(2):243-250.
Title: SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models.
Author: Jiang, Xi-Fei|Dai, Yang|Peng, Xia|Shen, Yan-Yan|Su, Yi|Wei, Man-Man|Liu, Wei-Ren|Ding, Zhen-Bin|Zhang, Ao|Shi, Ying-Hong|Ai, Jing
PMID: 28905937
Journal: Int J Mol Med. 2018 Apr;41(4):2389-2396.
Title: Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway.
Author: Su, Chin-Cheng
PMID: 29393362
Journal: Biomed Pharmacother. 2018 Apr;100:176-183.
Title: Astragalus polysaccharide enhanced antitumor effects of Apatinib in gastric cancer AGS cells by inhibiting AKT signalling pathway.
Author: Wu, Jun|Yu, Junxian|Wang, Jing|Zhang, Chenguang|Shang, Kun|Yao, Xiaojun|Cao, Bangwei
PMID: 29428665
Journal: Oncotarget. 2017 Dec 19;9(8):8120-8132.
Title: Efficacy and safety of targeting VEGFR drugs in treatment for advanced or metastatic gastric cancer: a systemic review and meta-analysis.
Author: Liu, Duanrui|Ma, Xiaoli|Xiao, Dongjie|Jia, Yanfei|Wang, Yunshan
PMID: 29487720
Journal: Pathol Res Pract. 2018 Apr;214(4):560-564.
Title: VEGFR-2 as a novel predictor of survival in gastric cancer: A systematic review and meta-analysis.
Author: Li, Teng|Yu, Jing|Luo, Xinyu|Ren, Weiguo|Zhang, Yue|Cao, Bangwei
PMID: 29572120
Journal: Cesk Patol. 2018 Spring;54(1):23-26.
Title: [Predictive diagnostics of gastric cancer in 2018].
Author: Daum, Ondrej|Dubova, Magdalena|Skalova, Alena|Rozkos, Tomas|Laco, Jan
PMID: 29631408
Journal: Drugs. 2018 May;78(7):747-758.
Title: Apatinib: A Review in Advanced Gastric Cancer and Other Advanced Cancers.
Author: Scott, Lesley J
PMID: 29663291
Journal: J Mol Histol. 2018 May 14. pii: 10.1007/s10735-018-9777-0.
Title: VEGFA and VEGFR2 RNAscope determination in gastric cancer.
Author: Tamma, Roberto|Annese, Tiziana|Ruggieri, Simona|Marzullo, Andrea|Nico, Beatrice|Ribatti, Domenico
PMID: 29761299
Journal: Exp Ther Med. 2018 Jun;15(6):5344-5352.
Title: Contrast-enhanced computed tomography combined with Chitosan-Fe3O4 nanoparticles targeting fibroblast growth factor receptor and vascular endothelial growth factor receptor in the screening of early esophageal cancer.
Author: Gai, Juanjuan|Gao, Zhenli|Song, Liqiang|Xu, Yongyun|Liu, Weixin|Zhao, Chuanxin
PMID: 29805549
Journal: Oncotarget. 2018 May 11;9(36):24548-24560.
Title: Apatinib as targeted therapy for sarcoma.
Author: Li, Feng|Liao, Zhichao|Zhang, Chao|Zhao, Jun|Xing, Ruwei|Teng, Sheng|Zhang, Jin|Yang, Yun|Yang, Jilong
PMID: 29849960
Journal: BMC Cancer. 2018 May 31;18(1):618.
Title: Apatinib treatment for KIT- and KDR-amplified angiosarcoma: a case report.
Author: Yang, Lishu|Liu, Lizhu|Han, Bo|Han, Wei|Zhao, Meng
PMID: 29855279
Journal: Onco Targets Ther. 2018 Jul 16;11:4047-4050.
Title: Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma.
Author: Li, Xiaofen|Li, Xia|Fang, Xuefeng|Yuan, Ying
PMID: 30038504
Journal: Sci Rep. 2018 Aug 7;8(1):11844.
Title: CT textural analysis of gastric cancer: correlations with immunohistochemical biomarkers.
Author: Liu, Shunli|Shi, Hua|Ji, Changfeng|Guan, Wenxian|Chen, Ling|Sun, Yingshi|Tang, Lei|Guan, Yue|Li, Weifeng|Ge, Yun|He, Jian|Liu, Song|Zhou, Zhengyang
PMID: 30087428
Journal: J Immunother Cancer. 2018 Oct 11;6(1):106.
Title: Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8(+) T cells in the tumor microenvironment.
Author: Tada, Yasuko|Togashi, Yosuke|Kotani, Daisuke|Kuwata, Takeshi|Sato, Eichi|Kawazoe, Akihito|Doi, Toshihiko|Wada, Hisashi|Nishikawa, Hiroyoshi|Shitara, Kohei
PMID: 30314524
Journal: Onco Targets Ther. 2018 Oct 5;11:6539-6554.
Title: The efficacy and safety of apatinib for refractory malignancies: a review and meta-analysis.
Author: Sun, Dantong|Hou, Helei|Zhang, Chuantao|Zhang, Xiaochun
PMID: 30323627
Journal: Expert Opin Drug Saf. 2018 Nov;17(11):1145-1150.
Title: The safety of apatinib for the treatment of gastric cancer.
Author: Geng, Ruixuan|Song, Li|Li, Jin|Zhao, Lin
PMID: 30324820
Journal: Clin Cancer Res. 2018 Oct 22. pii: 1078-0432.CCR-18-2484.
Title: Anti-PD-1 Antibody SHR-1210 combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study.
Author: Xu, Jian Ming|Zhang, Yun|Jia, Ru|Yue, Chun Yan|Chang, Lianpeng|Liu, Rong-Rui|Zhang, Gairong|Zhao, Chuan Hua|Zhang, Yao Yue|Chen, Chun Xia|Wang, Yan|Yi, Xin|Hu, Zhiyuan|Zou, Jian Jun|Wang, Quan Ren
PMID: 30348638
Journal: Drugs. 2018 Oct 24. pii: 10.1007/s40265-018-0998-z.
Title: Fruquintinib: First Global Approval.
Author: Shirley, Matt
PMID: 30357594
Journal: Cancer Biol Ther. 2018 Oct 31:1-8.
Title: The VEGFR-2 protein and the VEGFR-2 rs1870377 A>T genetic polymorphism are prognostic factors for gastric cancer.
Author: Zhu, Xueru|Wang, Yiwei|Xue, Wenji|Wang, Ruifen|Wang, Lifeng|Zhu, Mei-Ling|Zheng, Leizhen
PMID: 30380970