Primary Site >> Biliary tract Cancer
Gene >> KDR
| 1. | |||||||||||
| Journal: | J Gastrointest Cancer. 2007;38(2-4):154-6. | ||||||||||
| Title: | Effective palliation of advanced cholangiocarcinoma with sorafenib: a two-patient case report. | ||||||||||
| Author: | LaRocca, Renato V|Hicks, Matthew D|Mull, Lennea|Foreman, Brenda | ||||||||||
| PMID: | 19089671 | ||||||||||
| 2. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2007 Dec 18;87(47):3329-34. | ||||||||||
| Title: | [Effects of vascular endothelial growth factor (VEGF) antisense oligodeoxynucleotide on mRNA and expression of VEGF, flt-1, and kinase insert domain containing receptor and VEGF excretion in human gallbladder carcinoma cells]. | ||||||||||
| Author: | Fang, He-Qing|Li, Hai-Jun|Liu, Ying-Bin|Wang, Xu-An|Ma, Xiao-Ming|Kong, Ying|Chen, Yan|Chen, De-Qin|Weng, Wei-Hong|Zhang, Zhi-Ping|Devkota, K-R|Wang, Jian-Wei|Li, Jiang-Tao|Cao, Li-Ping|Peng, Shu-You | ||||||||||
| PMID: | 18478945 | ||||||||||
| 3. | |||||||||||
| Journal: | Dig Liver Dis. 2009 Feb;41(2):156-63. | ||||||||||
| Title: | Estrogens stimulate the proliferation of human cholangiocarcinoma by inducing the expression and secretion of vascular endothelial growth factor. | ||||||||||
| Author: | Mancino, A|Mancino, M G|Glaser, S S|Alpini, G|Bolognese, A|Izzo, L|Francis, H|Onori, P|Franchitto, A|Ginanni-Corradini, S|Gaudio, E|Alvaro, D | ||||||||||
| PMID: | 18395502 | ||||||||||
| 4. | |||||||||||
| Journal: | Liver Int. 2009 Aug;29(7):1031-42. | ||||||||||
| Title: | Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression. | ||||||||||
| Author: | Fava, Giammarco|Demorrow, Sharon|Gaudio, Eugenio|Franchitto, Antonio|Onori, Paolo|Carpino, Guido|Glaser, Shannon|Francis, Heather|Coufal, Monique|Marucci, Luca|Alvaro, Domenico|Marzioni, Marco|Horst, Trenton|Mancinelli, Romina|Benedetti, Antonio|Alpini, G | ||||||||||
| PMID: | 19291182 | ||||||||||
| 5. | |||||||||||
| Journal: | Br J Cancer. 2009 Apr 21;100(8):1257-66. | ||||||||||
| Title: | Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma. | ||||||||||
| Author: | Yoshikawa, D|Ojima, H|Kokubu, A|Ochiya, T|Kasai, S|Hirohashi, S|Shibata, T | ||||||||||
| PMID: | 19319137 | ||||||||||
| 6. | |||||||||||
| Journal: | Br J Cancer. 2010 Jan 5;102(1):68-72. | ||||||||||
| Title: | Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. | ||||||||||
| Author: | Bengala, C|Bertolini, F|Malavasi, N|Boni, C|Aitini, E|Dealis, C|Zironi, S|Depenni, R|Fontana, A|Del Giovane, C|Luppi, G|Conte, P | ||||||||||
| PMID: | 19935794 | ||||||||||
| 7. | |||||||||||
| Journal: | Hepatogastroenterology. 2010 May-Jun;57(99-100):426-9. | ||||||||||
| Title: | Effective treatment of advanced cholangiocarcinoma by hepatic arterial infusion chemotherapy combination with sorafenib: one case report from China. | ||||||||||
| Author: | Qun, Wang|Tao, Yin | ||||||||||
| PMID: | 20698202 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Cell Biochem. 2010 Dec;345(1-2):77-89. | ||||||||||
| Title: | Vascular endothelial growth factor-C promotes the growth and invasion of gallbladder cancer via an autocrine mechanism. | ||||||||||
| Author: | Chen, Yanling|Jiang, Lei|She, Feifei|Tang, Nanhong|Wang, Xiaoqian|Li, Xiujin|Han, Shenghua|Zhu, Jinhai | ||||||||||
| PMID: | 20734221 | ||||||||||
| 9. | |||||||||||
| Journal: | Ann Surg Oncol. 2013 May;20(5):1470-81. | ||||||||||
| Title: | Regional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression. | ||||||||||
| Author: | Butte, Jean M|Torres, Javiera|Veras, Emanuela F|Matsuo, Kenichi|Gonen, Mithat|D'Angelica, Michael I|Waugh, Enrique|Meneses, Manuel|Inayama, Yoshiyaki|Fong, Yuman|Dematteo, Ronald P|De La Fuente, Hernan|Endo, Itaru|Klimstra, David S|Jarnagin, William R | ||||||||||
| PMID: | 23212762 | ||||||||||
| 10. | |||||||||||
| Journal: | Anticancer Res. 2013 Oct;33(10):4619-26. | ||||||||||
| Title: | Effects of single nucleotide polymorphisms on treatment outcomes and toxicity in patients treated with sunitinib. | ||||||||||
| Author: | Maeng, Chi Hoon|Yi, Jun Ho|Lee, Jeeyun|Hong, Jung Yong|Choi, Moon Ki|Jung, Hyun Ae|Park, Joon Oh|Park, Se Hoon|Park, Young Suk|Kang, Won Ki|Lim, Ho Yeong | ||||||||||
| PMID: | 24123039 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2013 Nov 28;8(11):e81347. | ||||||||||
| Title: | Down-regulation of Gab1 inhibits cell proliferation and migration in hilar cholangiocarcinoma. | ||||||||||
| Author: | Sang, Haiquan|Li, Tingting|Li, Hangyu|Liu, Jingang | ||||||||||
| PMID: | 24312291 | ||||||||||
| 12. | |||||||||||
| Journal: | Eur J Cancer. 2014 Dec;50(18):3125-35. | ||||||||||
| Title: | Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme. | ||||||||||
| Author: | Moehler, M|Maderer, A|Schimanski, C|Kanzler, S|Denzer, U|Kolligs, F T|Ebert, M P|Distelrath, A|Geissler, M|Trojan, J|Schutz, M|Berie, L|Sauvigny, C|Lammert, F|Lohse, A|Dollinger, M M|Lindig, U|Duerr, E M|Lubomierski, N|Zimmermann, S|Wachtlin, D|Kaiser, A- | ||||||||||
| PMID: | 25446376 | ||||||||||
| 13. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2014 Jun;44(6):570-8. | ||||||||||
| Title: | Axitinib (AG-013736), an oral specific VEGFR TKI, shows potential therapeutic utility against cholangiocarcinoma. | ||||||||||
| Author: | Takahashi, Hiroyuki|Ojima, Hidenori|Shimizu, Hiroko|Furuse, Junji|Furukawa, Hiroyuki|Shibata, Tatsuhiro | ||||||||||
| PMID: | 24755544 | ||||||||||
| 14. | |||||||||||
| Journal: | Invest New Drugs. 2015 Apr;33(2):490-5. | ||||||||||
| Title: | Phase II trial of combination therapy of gemcitabine plus anti-angiogenic vaccination of elpamotide in patients with advanced or recurrent biliary tract cancer. | ||||||||||
| Author: | Matsuyama, Masato|Ishii, H|Furuse, J|Ohkawa, S|Maguchi, H|Mizuno, N|Yamaguchi, T|Ioka, T|Ajiki, T|Ikeda, M|Hakamada, K|Yamamoto, M|Yamaue, H|Eguchi, K|Ichikawa, W|Miyazaki, M|Ohashi, Y|Sasaki, Y | ||||||||||
| PMID: | 25502982 | ||||||||||
| 15. | |||||||||||
| Journal: | Tumour Biol. 2015 Nov;36(11):8367-77. | ||||||||||
| Title: | Gab1 regulates proliferation and migration through the PI3K/Akt signaling pathway in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Sang, Haiquan|Li, Tingting|Li, Hangyu|Liu, Jingang | ||||||||||
| PMID: | 26014518 | ||||||||||
| 16. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1;309(11):G865-73. | ||||||||||
| Title: | Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors. | ||||||||||
| Author: | Mancinelli, Romina|Glaser, Shannon|Francis, Heather|Carpino, Guido|Franchitto, Antonio|Vetuschi, Antonella|Sferra, Roberta|Pannarale, Luigi|Venter, Julie|Meng, Fanyin|Alpini, Gianfranco|Onori, Paolo|Gaudio, Eugenio | ||||||||||
| PMID: | 26451003 | ||||||||||
| 17. | |||||||||||
| Journal: | Medicine (Baltimore). 2016 Aug;95(33):e4584. | ||||||||||
| Title: | Chemotherapy for advanced biliary tract carcinoma: A meta-analysis of randomized controlled trials. | ||||||||||
| Author: | Chen, Lawrence|Chen, Chiehfeng|Yen, Yun|Tam, Ka-Wai | ||||||||||
| PMID: | 27537589 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer. 2017 Jun 1;123(11):1979-1988. | ||||||||||
| Title: | A phase 2 and biomarker study of cabozantinib in patients with advanced cholangiocarcinoma. | ||||||||||
| Author: | Goyal, Lipika|Zheng, Hui|Yurgelun, Matthew B|Abrams, Thomas A|Allen, Jill N|Cleary, James M|Knowles, Michelle|Regan, Eileen|Reardon, Amanda|Khachatryan, Anna|Jain, Rakesh K|Nardi, Valentina|Borger, Darrell R|Duda, Dan G|Zhu, Andrew X | ||||||||||
| PMID: | 28192597 | ||||||||||
| 19. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2017 Apr;37(2):172-178. | ||||||||||
| Title: | Efficacy and safety of chemotherapy with or without targeted therapy in biliary tract cancer: A meta-analysis of 7 randomized controlled trials. | ||||||||||
| Author: | Zhuang, Xin|Xiao, Ya-Ping|Tan, Ling-Hua|Wang, Lu-Ting|Cao, Qian|Qu, Gui-Fang|Xiao, Shuang|Duan, Hua-Xin | ||||||||||
| PMID: | 28397047 | ||||||||||
| 20. | |||||||||||
| Journal: | Anticancer Res. 2017 Jul;37(7):3711-3715. | ||||||||||
| Title: | Axitinib for Gemcitabine-refractory Advanced Biliary Tract Cancer: Report of 5 Cases. | ||||||||||
| Author: | Okano, Naohiro|Kasuga, Akiyoshi|Kawai, Kirio|Kobayashi, Takaaki|Naruge, Daisuke|Nagashima, Fumio|Furuse, Junji | ||||||||||
| PMID: | 28668864 | ||||||||||
| 21. | |||||||||||
| Journal: | Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018. | ||||||||||
| Title: | Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers. | ||||||||||
| Author: | Papadopoulou, Kyriaki|Murray, Samuel|Manousou, Kyriaki|Tikas, Ioannis|Dervenis, Christos|Sgouros, Joseph|Rontogianni, Dimitra|Lakis, Sotirios|Bobos, Mattheos|Poulios, Christos|Pervana, Stavroula|Lazaridis, Georgios|Fountzilas, George|Kotoula, Vassiliki | ||||||||||
| PMID: | 29416916 | ||||||||||
| 22. | |||||||||||
| Journal: | J Gastrointest Oncol. 2018 Feb;9(1):111-125. | ||||||||||
| Title: | Investigation of targetable predictive and prognostic markers in gallbladder carcinoma. | ||||||||||
| Author: | Neyaz, Azfar|Husain, Nuzhat|Gupta, Sameer|Kumari, Swati|Arora, Aditi|Awasthi, Namrata Puneet|Malhotra, Kiran Preet|Misra, Sanjeev | ||||||||||
| PMID: | 29564177 | ||||||||||
| 23. | |||||||||||
| Journal: | Br J Cancer. 2018 Jul;119(1):27-35. | ||||||||||
| Title: | Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. | ||||||||||
| Author: | Backen, Alison C|Lopes, Andre|Wasan, Harpreet|Palmer, Daniel H|Duggan, Marian|Cunningham, David|Anthoney, Alan|Corrie, Pippa G|Madhusudan, Srinivasan|Maraveyas, Anthony|Ross, Paul J|Waters, Justin S|Steward, William P|Rees, Charlotte|McNamara, Mairead G|B | ||||||||||
| PMID: | 29925934 | ||||||||||
| 24. | |||||||||||
| Journal: | Pathol Res Pract. 2018 Aug;214(8):1136-1141. | ||||||||||
| Title: | Microvessel density and angiogenesis in primary hepatic malignancies: Differential expression of CD31 and VEGFR-2 in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Bosmuller, Hans|Pfefferle, Vanessa|Bittar, Zeid|Scheble, Veit|Horger, Marius|Sipos, Bence|Fend, Falko | ||||||||||
| PMID: | 29935812 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncogene. 2018 Sep 3. pii: 10.1038/s41388-018-0485-8. | ||||||||||
| Title: | HMGB1 correlates with angiogenesis and poor prognosis of perihilar cholangiocarcinoma via elevating VEGFR2 of vessel endothelium. | ||||||||||
| Author: | Xu, Yun-Fei|Liu, Zeng-Li|Pan, Chang|Yang, Xiao-Qing|Ning, Shang-Lei|Liu, Hong-Da|Guo, Sen|Yu, Jin-Ming|Zhang, Zong-Li | ||||||||||
| PMID: | 30177842 | ||||||||||