Primary Site >> Stomach Cancer

Gene >> KDM1A

Journal: Hum Pathol. 2010 Feb;41(2):181-9.
Title: H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
Author: Magerl, Christian|Ellinger, Jorg|Braunschweig, Till|Kremmer, Elisabeth|Koch, Lin Kristin|Holler, Tobias|Buttner, Reinhard|Luscher, Bernhard|Gutgemann, Ines
PMID: 19896696
Journal: J Med Chem. 2013 Nov 14;56(21):8543-60.
Title: Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.
Author: Zheng, Yi-Chao|Duan, Ying-Chao|Ma, Jin-Lian|Xu, Rui-Min|Zi, Xiaolin|Lv, Wen-Lei|Wang, Meng-Meng|Ye, Xian-Wei|Zhu, Shun|Mobley, David|Zhu, Yan-Yan|Wang, Jun-Wei|Li, Jin-Feng|Wang, Zhi-Ru|Zhao, Wen|Liu, Hong-Min
PMID: 24131029
Journal: J Med Chem. 2015 Feb 26;58(4):1705-16.
Title: Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.
Author: Ma, Li-Ying|Zheng, Yi-Chao|Wang, Sai-Qi|Wang, Bo|Wang, Zhi-Ru|Pang, Lu-Ping|Zhang, Miao|Wang, Jun-Wei|Ding, Lina|Li, Juan|Wang, Cong|Hu, Biao|Liu, Ying|Zhang, Xiao-Dan|Wang, Jia-Jia|Wang, Zhi-Jian|Zhao, Wen|Liu, Hong-Min
PMID: 25610955
Journal: Biomed Pharmacother. 2016 Aug;82:498-508.
Title: Interference of lysine-specific demethylase 1 inhibits cellular invasion and proliferation in vivo in gastric cancer MKN-28 cells.
Author: Li, Yan|Tian, Xin|Sui, Cheng-Guang|Jiang, You-Hong|Liu, Yun-Peng|Meng, Fan-Dong
PMID: 27470390
Journal: Cancer Res. 2016 Nov 1;76(21):6299-6310.
Title: LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1.
Author: Sun, Ming|Nie, Fengqi|Wang, Yunfei|Zhang, Zhihong|Hou, Jiakai|He, Dandan|Xie, Min|Xu, Lin|De, Wei|Wang, Zhaoxia|Wang, Jun
PMID: 27651312
Journal: Mol Cancer. 2017 Apr 26;16(1):82.
Title: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer.
Author: Liu, Zhili|Chen, Zhenyao|Fan, Ruihua|Jiang, Bin|Chen, Xin|Chen, Qinnan|Nie, Fengqi|Lu, Kaihua|Sun, Ming
PMID: 28441948
Journal: Mol Cancer. 2017 Apr 26;16(1):82.
Title: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer.
Author: Liu, Zhili|Chen, Zhenyao|Fan, Ruihua|Jiang, Bin|Chen, Xin|Chen, Qinnan|Nie, Fengqi|Lu, Kaihua|Sun, Ming
PMID: 30079558
Journal: Mol Cancer. 2017 Apr 26;16(1):82.
Title: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer.
Author: Liu, Zhili|Chen, Zhenyao|Fan, Ruihua|Jiang, Bin|Chen, Xin|Chen, Qinnan|Nie, Fengqi|Lu, Kaihua|Sun, Ming
PMID: 29760541
Journal: Bioorg Med Chem Lett. 2017 Nov 15;27(22):5036-5039.
Title: Discovery of tranylcypromine analogs with an acylhydrazone substituent as LSD1 inactivators: Design, synthesis and their biological evaluation.
Author: Sun, Kai|Peng, Jia-Di|Suo, Feng-Zhi|Zhang, Ting|Fu, Yun-Dong|Zheng, Yi-Chao|Liu, Hong-Min
PMID: 29037950
Journal: Mol Ther. 2017 Apr 5;25(4):1014-1026.
Title: Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer.
Author: Huang, Mingde|Hou, Jiakai|Wang, Yunfei|Xie, Min|Wei, Chenchen|Nie, Fengqi|Wang, Zhaoxia|Sun, Ming
PMID: 28214253
Journal: J Hematol Oncol. 2017 Feb 16;10(1):48.
Title: Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer.
Author: Qi, Fuzhen|Liu, Xianghua|Wu, Hao|Yu, Xiang|Wei, Chenchen|Huang, Xiaodan|Ji, Guozhong|Nie, Fengqi|Wang, Keming
PMID: 28209205
Journal: Mol Cancer. 2017 Feb 16;16(1):39.
Title: LincRNAFEZF1-AS1 represses p21 expression to promote gastric cancer proliferation through LSD1-Mediated H3K4me2 demethylation.
Author: Liu, Yan-Wen|Xia, Rui|Lu, Kai|Xie, Min|Yang, Fen|Sun, Ming|De, Wei|Wang, Cailian|Ji, Guozhong
PMID: 28209170
Journal: Oncogenesis. 2017 Jan 23;6(1):e288.
Title: Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer.
Author: Ding, J|Xie, M|Lian, Y|Zhu, Y|Peng, P|Wang, J|Wang, L|Wang, K
PMID: 28112720
Journal: Oncotarget. 2017 Jun 13;8(24):38227-38238.
Title: Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression.
Author: Nie, Fengqi|Yu, Xiang|Huang, Mingde|Wang, Yunfei|Xie, Min|Ma, Hongwei|Wang, Zhaoxia|De, Wei|Sun, Ming
PMID: 27246976
Journal: J Cell Biochem. 2018 Apr;119(4):3338-3351.
Title: MicroRNA-329 inhibits cell proliferation and tumor growth while facilitates apoptosis via negative regulation of KDM1A in gastric cancer.
Author: Cai, Lisheng|Chen, Qiuxian|Fang, Shunyong|Lian, Mingqiao|Cai, Mingzhi
PMID: 29130516
Journal: Cancer Gene Ther. 2018 May;25(3-4):58-67.
Title: Long non-coding RNA DLEU1 predicts poor prognosis of gastric cancer and contributes to cell proliferation by epigenetically suppressing KLF2.
Author: Li, Xiaobin|Li, Zongze|Liu, Ziwen|Xiao, Jianchun|Yu, Shuting|Song, Yimin
PMID: 29282356
Journal: J Exp Clin Cancer Res. 2018 Jan 27;37(1):13.
Title: Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and beta-catenin in gastric cancer.
Author: Xu, Yongcan|Yu, Xiang|Wei, Chenchen|Nie, Fengqi|Huang, Mingde|Sun, Ming
PMID: 29374493
Journal: J Cell Biochem. 2018 Jun;119(6):4957-4966.
Title: Lysine-specific demethylase 1 activation by vitamin B2 attenuates efficacy of apatinib for proliferation and migration of gastric cancer cell MGC-803.
Author: Ma, Jin-Lian|Zhang, Ting|Suo, Feng-Zhi|Chang, Jiao|Wan, Xiang-Bin|Feng, Xue-Jian|Zheng, Yi-Chao|Liu, Hong-Min
PMID: 29384217
Journal: Elife. 2018 Jan 31;7. pii: 29511.
Title: Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.
Author: Hong, Xuehui|Huang, He|Qiu, Xingfeng|Ding, Zhijie|Feng, Xing|Zhu, Yuekun|Zhuo, Huiqin|Hou, Jingjing|Zhao, Jiabao|Cai, Wangyu|Sha, Ruihua|Hong, Xinya|Li, Yongxiang|Song, Hongjiang|Zhang, Zhiyong
PMID: 29384474
Journal: Oncogene. 2018 Sep;37(36):5020-5036.
Title: Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD1, and predicts poor prognosis in gastric cancer.
Author: Xu, Tong-Peng|Wang, Wen-Yu|Ma, Pei|Shuai, You|Zhao, Kun|Wang, Yan-Fen|Li, Wei|Xia, Rui|Chen, Wen-Ming|Zhang, Er-Bao|Shu, Yong-Qian
PMID: 29789713
Journal: J Biomol Struct Dyn. 2018 Oct 26:1-31.
Title: Identifying the Novel Inhibitors of Lysine specific demethylase 1 (LSD1) Combining Pharmacophore-Based and Structure-Based Virtual Screening.
Author: Sun, Xudong|Zheng, Yichao|Ma, Chaoya|Yang, Jing|Gao, Qibing|Yan, Ying|Wang, Zhizheng|Li, Wen|Zhao, Wen|Liu, Hongmin|Ding, Lina
PMID: 30366512