Primary Site >> Pancreatic Cancer
Gene >> IL2RA
| 1. | |||||||||||
| Journal: | Cancer Immunol Immunother. 1991;33(6):398-402. | ||||||||||
| Title: | Cytotoxic activity and phenotypic characteristics of lymphocyte subsets after therapy of cancer patients with interleukin-2. | ||||||||||
| Author: | Weidmann, E|Bergmann, L|Hechler, P|Mitrou, P S | ||||||||||
| PMID: | 1878892 | ||||||||||
| 2. | |||||||||||
| Journal: | Biotherapy. 1993;6(1):25-32. | ||||||||||
| Title: | Autologous tumour-specific cytotoxic T-cell clone established from tumour-infiltrating lymphocytes (TIL) of malignant ascites in the absence of recombinant interleukin 2(rIL2): activation by autologous tumour cell alone. | ||||||||||
| Author: | Katano, M|Nagumo, F|Kubota, E|Yamamoto, H|Matsuo, T|Hisatsugu, T|Tadano, J | ||||||||||
| PMID: | 8507542 | ||||||||||
| 3. | |||||||||||
| Journal: | Biotherapy. 1993;6(1):33-9. | ||||||||||
| Title: | The expression and biological activity of IL-2 receptor on a human pancreas cancer cell line. | ||||||||||
| Author: | Kawami, H|Yoshida, K|Yamaguchi, Y|Saeki, T|Toge, T | ||||||||||
| PMID: | 8507543 | ||||||||||
| 4. | |||||||||||
| Journal: | J Mol Med (Berl). 1995 Aug;73(8):409-16. | ||||||||||
| Title: | Tumor-associated lymphocytes (TAL) are competent to produce higher levels of cytokines in neoplastic pleural and peritoneal effusions than those found in sera and are able to release into culture higher levels of IL-2 and IL-6 than those released by PBMC. | ||||||||||
| Author: | Mantovani, G|Maccio, A|Versace, R|Pisano, M|Lai, P|Esu, S|Ghiani, M|Dessi, D|Turnu, E|Santona, M C | ||||||||||
| PMID: | 8528743 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Lett. 1998 Dec 25;134(2):193-9. | ||||||||||
| Title: | Prognostic significance of soluble interleukin-2 receptor-alpha in adenocarcinoma of the pancreas. | ||||||||||
| Author: | Gansauge, F|Steinbach, G|Gansauge, S|Konig, H H|Muller, J|Grunert, A|Beger, H G | ||||||||||
| PMID: | 10025881 | ||||||||||
| 6. | |||||||||||
| Journal: | Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):69-72. | ||||||||||
| Title: | [Prognostic value of molecular biologogy and immunologic parameters in human pancreatic carcinoma]. | ||||||||||
| Author: | Gansauge, F|Gansauge, S|Muller, J|Schmid, E|Beger, H G | ||||||||||
| PMID: | 14518215 | ||||||||||
| 7. | |||||||||||
| Journal: | Glycoconj J. 2001 Nov-Dec;18(11-12):931-42. | ||||||||||
| Title: | MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment. | ||||||||||
| Author: | Mukherjee, P|Ginardi, A R|Madsen, C S|Tinder, T L|Jacobs, F|Parker, J|Agrawal, B|Longenecker, B M|Gendler, S J | ||||||||||
| PMID: | 12820727 | ||||||||||
| 8. | |||||||||||
| Journal: | J Immunol. 2002 Sep 1;169(5):2756-61. | ||||||||||
| Title: | Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. | ||||||||||
| Author: | Liyanage, Udaya K|Moore, Todd T|Joo, Hong-Gu|Tanaka, Yoshiyuki|Herrmann, Virginia|Doherty, Gerard|Drebin, Jeffrey A|Strasberg, Steven M|Eberlein, Timothy J|Goedegebuure, Peter S|Linehan, David C | ||||||||||
| PMID: | 12193750 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2004 Nov;53(11):1018-26. Epub 2004 Jun 5. | ||||||||||
| Title: | Dendritic cells reduce number and function of CD4+CD25+ cells in cytokine-induced killer cells derived from patients with pancreatic carcinoma. | ||||||||||
| Author: | Schmidt, Jan|Eisold, Sven|Buchler, Markus W|Marten, Angela | ||||||||||
| PMID: | 15185013 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Biol Markers. 2004 Jul-Sep;19(3):196-202. | ||||||||||
| Title: | Can IL-2R alpha be a valuable marker along with CA 19-9 in the diagnosis of chronic pancreatitis and pancreatic cancer? | ||||||||||
| Author: | Kayhan, B|Kayhan, B|Akdogan, M | ||||||||||
| PMID: | 15503821 | ||||||||||
| 11. | |||||||||||
| Journal: | Immunol Res. 2005;32(1-3):155-68. | ||||||||||
| Title: | CD25+ CD4+ regulatory T-cells in cancer. | ||||||||||
| Author: | Linehan, David C|Goedegebuure, Peter S | ||||||||||
| PMID: | 16106066 | ||||||||||
| 12. | |||||||||||
| Journal: | J Immunother. 2006 Jul-Aug;29(4):416-24. | ||||||||||
| Title: | Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma. | ||||||||||
| Author: | Liyanage, Udaya K|Goedegebuure, Peter S|Moore, Todd T|Viehl, Carsten T|Moo-Young, Tricia A|Larson, Justin W|Frey, Daniel M|Ehlers, Jesmin P|Eberlein, Timothy J|Linehan, David C | ||||||||||
| PMID: | 16799337 | ||||||||||
| 13. | |||||||||||
| Journal: | Ann Surg Oncol. 2006 Sep;13(9):1252-8. Epub 2006 Sep 3. | ||||||||||
| Title: | Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice. | ||||||||||
| Author: | Viehl, Carsten T|Moore, Todd T|Liyanage, Udaya K|Frey, Daniel M|Ehlers, Jesmin P|Eberlein, Timothy J|Goedegebuure, Peter S|Linehan, David C | ||||||||||
| PMID: | 16952047 | ||||||||||
| 14. | |||||||||||
| Journal: | Pancreas. 2006 Nov;33(4):386-90. | ||||||||||
| Title: | Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients. | ||||||||||
| Author: | Ikemoto, Tetsuya|Yamaguchi, Takeshi|Morine, Yuji|Imura, Satoru|Soejima, Yuji|Fujii, Masahiko|Maekawa, Yoichi|Yasutomo, Koji|Shimada, Mitsuo | ||||||||||
| PMID: | 17079944 | ||||||||||
| 15. | |||||||||||
| Journal: | Langenbecks Arch Surg. 2007 May;392(3):353-8. | ||||||||||
| Title: | Systemic immune dysfunction in pancreatic cancer patients. | ||||||||||
| Author: | Poch, Bertram|Lotspeich, Errki|Ramadani, Marco|Gansauge, Susanne|Beger, Hans G|Gansauge, Frank | ||||||||||
| PMID: | 17235586 | ||||||||||
| 16. | |||||||||||
| Journal: | J Natl Cancer Inst. 2007 Aug 1;99(15):1188-99. Epub 2007 Jul 24. | ||||||||||
| Title: | Role of tumor endothelium in CD4+ CD25+ regulatory T cell infiltration of human pancreatic carcinoma. | ||||||||||
| Author: | Nummer, Daniel|Suri-Payer, Elisabeth|Schmitz-Winnenthal, Hubertus|Bonertz, Andreas|Galindo, Luis|Antolovich, Dalibor|Koch, Moritz|Buchler, Markus|Weitz, Jurgen|Schirrmacher, Volker|Beckhove, Philipp | ||||||||||
| PMID: | 17652277 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Transl Sci. 2008 Dec;1(3):228-39. | ||||||||||
| Title: | Effective depletion of regulatory T cells allows the recruitment of mesothelin-specific CD8 T cells to the antitumor immune response against a mesothelin-expressing mouse pancreatic adenocarcinoma. | ||||||||||
| Author: | Leao, Ihid C|Ganesan, Priya|Armstrong, Todd D|Jaffee, Elizabeth M | ||||||||||
| PMID: | 20357913 | ||||||||||
| 18. | |||||||||||
| Journal: | Pancreas. 2009 Jul;38(5):602-4. | ||||||||||
| Title: | Enhanced inhibition of tumor growth with depletion of CD25 regulatory cells and intratumoral immunization with tumor RNA-pulsed dendritic cells in a C57BL/6 pancreatic tumor model. | ||||||||||
| Author: | Linke, Andrea|Brossart, Peter|Schmidt-Wolf, Ingo G H|Gonzalez-Carmona, Maria A|Ziske, Carsten|Messmer, Davorka|Schmitz, Volker|Sauerbruch, Tilman | ||||||||||
| PMID: | 19550282 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncol Rep. 2009 Aug;22(2):337-43. | ||||||||||
| Title: | Enhancement of anti-tumor immunity by high levels of Th1 and Th17 with a combination of dendritic cell fusion hybrids and regulatory T cell depletion in pancreatic cancer. | ||||||||||
| Author: | Yamamoto, Masashi|Kamigaki, Takashi|Yamashita, Kimihiro|Hori, Yuichi|Hasegawa, Hiroshi|Kuroda, Daisuke|Moriyama, Hiroaki|Nagata, Masao|Ku, Yonson|Kuroda, Yoshikazu | ||||||||||
| PMID: | 19578774 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Cancer. 2011 Feb 15;128(4):897-907. | ||||||||||
| Title: | An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma. | ||||||||||
| Author: | Jacobs, Collin|Duewell, Peter|Heckelsmiller, Klaus|Wei, Jiwu|Bauernfeind, Franz|Ellermeier, Jonathan|Kisser, Ulrich|Bauer, Christian A|Dauer, Marc|Eigler, Andreas|Maraskovsky, Eugene|Endres, Stefan|Schnurr, Max | ||||||||||
| PMID: | 20473889 | ||||||||||
| 21. | |||||||||||
| Journal: | J Immunol. 2011 Jun 15;186(12):6933-44. | ||||||||||
| Title: | Novel TGF-beta antagonist inhibits tumor growth and angiogenesis by inducing IL-2 receptor-driven STAT1 activation. | ||||||||||
| Author: | Penafuerte, Claudia|Bautista-Lopez, Norma|Bouchentouf, Manaf|Birman, Elena|Forner, Kathy|Galipeau, Jacques | ||||||||||
| PMID: | 21551368 | ||||||||||
| 22. | |||||||||||
| Journal: | Pancreas. 2011 Oct;40(7):1131-7. | ||||||||||
| Title: | Pancreatic cancer alters human CD4+ T lymphocyte function: a piece in the immune evasion puzzle. | ||||||||||
| Author: | Fogar, Paola|Basso, Daniela|Fadi, Elisa|Greco, Eliana|Pantano, Giorgia|Padoan, Andrea|Bozzato, Dania|Facco, Monica|Sanzari, Maria Colomba|Teolato, Sara|Zambon, Carlo-Federico|Navaglia, Filippo|Semenzato, Gianpietro|Pedrazzoli, Sergio|Plebani, Mario | ||||||||||
| PMID: | 21792088 | ||||||||||
| 23. | |||||||||||
| Journal: | Pancreas. 2012 Apr;41(3):409-15. | ||||||||||
| Title: | Circulating CD4+CD25+ regulatory T cells in patients with pancreatic cancer. | ||||||||||
| Author: | Yamamoto, Tomohisa|Yanagimoto, Hiroaki|Satoi, Sohei|Toyokawa, Hideyoshi|Hirooka, Satoshi|Yamaki, So|Yui, Rintaro|Yamao, Jun|Kim, Songtae|Kwon, A-Hon | ||||||||||
| PMID: | 22158072 | ||||||||||
| 24. | |||||||||||
| Journal: | Clin Dev Immunol. 2012;2012:230625. | ||||||||||
| Title: | Reevaluating the concept of treating experimental tumors with a mixed bacterial vaccine: Coley's Toxin. | ||||||||||
| Author: | Maletzki, C|Klier, U|Obst, W|Kreikemeyer, B|Linnebacher, M | ||||||||||
| PMID: | 23193416 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Lett. 2013 Mar 1;330(1):22-32. | ||||||||||
| Title: | GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. | ||||||||||
| Author: | Fu, Junsheng|Rodova, Mariana|Roy, Sanjit K|Sharma, Jay|Singh, Karan P|Srivastava, Rakesh K|Shankar, Sharmila | ||||||||||
| PMID: | 23200667 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Clin Oncol. 2014 Feb;19(1):81-6. | ||||||||||
| Title: | Changes of immunological parameters with administration of Japanese Kampo medicine (Juzen-Taihoto/TJ-48) in patients with advanced pancreatic cancer. | ||||||||||
| Author: | Ikemoto, Tetsuya|Shimada, Mitsuo|Iwahashi, Shuichi|Saito, Yu|Kanamoto, Mami|Mori, Hiroki|Morine, Yuji|Imura, Satoru|Utsunomiya, Tohru | ||||||||||
| PMID: | 23443635 | ||||||||||
| 27. | |||||||||||
| Journal: | Clin Transl Oncol. 2014 Mar;16(3):330-5. | ||||||||||
| Title: | Changes in the immune cell population and cell proliferation in peripheral blood after gemcitabine-based chemotherapy for pancreatic cancer. | ||||||||||
| Author: | Homma, Y|Taniguchi, K|Nakazawa, M|Matsuyama, R|Mori, R|Takeda, K|Ichikawa, Y|Tanaka, K|Endo, I | ||||||||||
| PMID: | 23860726 | ||||||||||
| 28. | |||||||||||
| Journal: | J Transl Med. 2014 Jul 9;12:191. | ||||||||||
| Title: | Ipilimumab augments antitumor activity of bispecific antibody-armed T cells. | ||||||||||
| Author: | Yano, Hiroshi|Thakur, Archana|Tomaszewski, Elyse N|Choi, Minsig|Deol, Abhinav|Lum, Lawrence G | ||||||||||
| PMID: | 25008236 | ||||||||||
| 29. | |||||||||||
| Journal: | J Immunol. 2015 Aug 15;195(4):1883-90. | ||||||||||
| Title: | Innate Response to Human Cancer Cells with or without IL-2 Receptor Common gamma-Chain Function in NOD Background Mice Lacking Adaptive Immunity. | ||||||||||
| Author: | Nishime, Chiyoko|Kawai, Kenji|Yamamoto, Takehiro|Katano, Ikumi|Monnai, Makoto|Goda, Nobuhito|Mizushima, Tomoko|Suemizu, Hiroshi|Nakamura, Masato|Murata, Mitsuru|Suematsu, Makoto|Wakui, Masatoshi | ||||||||||
| PMID: | 26170385 | ||||||||||
| 30. | |||||||||||
| Journal: | Rinsho Byori. 2015 Oct;63(10):1202-6. | ||||||||||
| Title: | [Pathophysiology and Assessment of IgG4-Related Disease--Focus on Autoimmune Pancreatitis]. | ||||||||||
| Author: | Uehara, Takeshi | ||||||||||
| PMID: | 26897857 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncol Rep. 2016 Sep;36(3):1377-84. | ||||||||||
| Title: | Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cells. | ||||||||||
| Author: | Yuan, Bo|He, Jing|Kisoh, Keishi|Hayashi, Hideki|Tanaka, Sachiko|Si, Nan|Zhao, Hai-Yu|Hirano, Toshihiko|Bian, Baolin|Takagi, Norio | ||||||||||
| PMID: | 27431260 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Cancer. 2017 Oct 1;141(7):1458-1468. | ||||||||||
| Title: | Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy. | ||||||||||
| Author: | Santos, Joao Manuel|Havunen, Riikka|Siurala, Mikko|Cervera-Carrascon, Victor|Tahtinen, Siri|Sorsa, Suvi|Anttila, Marjukka|Karell, Pauliina|Kanerva, Anna|Hemminki, Akseli | ||||||||||
| PMID: | 28614908 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Res. 2017 Nov 1;77(21):5952-5962. | ||||||||||
| Title: | Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer. | ||||||||||
| Author: | D'Costa, Zenobia|Jones, Keaton|Azad, Abul|van Stiphout, Ruud|Lim, Su Y|Gomes, Ana L|Kinchesh, Paul|Smart, Sean C|Gillies McKenna, W|Buffa, Francesca M|Sansom, Owen J|Muschel, Ruth J|O'Neill, Eric|Fokas, Emmanouil | ||||||||||
| PMID: | 28765154 | ||||||||||
| 34. | |||||||||||
| Journal: | J Transl Med. 2018 Oct 25;16(1):294. | ||||||||||
| Title: | CD25 and TGF-beta blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer. | ||||||||||
| Author: | Pu, Ning|Zhao, Guochao|Yin, Hanlin|Li, Jian-Ang|Nuerxiati, Abulimiti|Wang, Dansong|Xu, Xuefeng|Kuang, Tiantao|Jin, Dayong|Lou, Wenhui|Wu, Wenchuan | ||||||||||
| PMID: | 30359281 | ||||||||||