Primary Site >> Colorectal Cancer

Gene >> IGFBP6

Journal: J Clin Invest. 1995 Jul;96(1):192-200.
Title: Cell polarity of the insulin-like growth factor system in human intestinal epithelial cells. Unique apical sorting of insulin-like growth factor binding protein-6 in differentiated human colon cancer cells.
Author: Remacle-Bonnet, M|Garrouste, F|el Atiq, F|Marvaldi, J|Pommier, G
PMID: 7542277
Journal: Int J Cancer. 1997 Sep 4;72(5):835-43.
Title: Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells.
Author: Remacle-Bonnet, M M|Garrouste, F L|Pommier, G J
PMID: 9311602
Journal: Mol Cell Endocrinol. 2001 Mar 28;174(1-2):121-7.
Title: Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells.
Author: Leng, S L|Leeding, K S|Whitehead, R H|Bach, L A
PMID: 11306178
Journal: Mol Cell Endocrinol. 2001 Oct 25;183(1-2):141-9.
Title: Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells.
Author: Oh, Y S|Kim, E J|Schaffer, B S|Kang, Y H|Binderup, L|MacDonald, R G|Park, J H
PMID: 11604234
Journal: J Cell Physiol. 2002 Jan;190(1):92-100.
Title: Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.
Author: Kim, Eun J|Kang, Young-Hee|Schaffer, Beverly S|Bach, Leon A|MacDonald, Richard G|Park, Jung H Y
PMID: 11807815
Journal: J Gastroenterol Hepatol. 2002 May;17(5):563-70.
Title: Decreased production of insulin-like growth factor-binding protein (IGFBP)-6 by transfection of colon cancer cells with an antisense IGFBP-6 cDNA construct leads to stimulation of cell proliferation.
Author: Kim, Eun J|Schaffer, Beverly S|Kang, Young-hee|Macdonald, Richard G|Park, Jung Hy
PMID: 12084030
Journal: Scand J Gastroenterol. 2004 May;39(5):464-9.
Title: Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line.
Author: Fan, C W|Chan, C C|Chao, C C K|Fan, H A|Sheu, D L|Chan, E C
PMID: 15180185
Journal: J Mol Endocrinol. 2004 Oct;33(2):377-86.
Title: Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.
Author: Headey, Stephen J|Leeding, Kerri S|Norton, Raymond S|Bach, Leon A
PMID: 15525596
Journal: Growth Horm IGF Res. 2005 Jun;15(3):185-92.
Title: IGFBP-6 five years on; not so 'forgotten'?
Author: Bach, Leon A
PMID: 15914054
Journal: J Biol Chem. 2007 Aug 3;282(31):22298-306.
Title: Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
Author: Fu, Ping|Thompson, Julian A|Bach, Leon A
PMID: 17519236
Journal: Mol Carcinog. 2008 Jan;47(1):9-21.
Title: Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
Author: Fenton, Jenifer I|Lavigne, Jackie A|Perkins, Susan N|Liu, Huaitian|Chandramouli, Gadisetti V R|Shih, Joanna H|Hord, Norman G|Hursting, Stephen D
PMID: 17620308
Journal: Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1511-8.
Title: Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
Author: Wu, Jian-Ye|Xu, Xuan-Fu|Xu, Ling|Niu, Pei-Qin|Wang, Feng|Hu, Guo-Yong|Wang, Xing-Peng|Guo, Chuan-Yong
PMID: 21940310
Journal: J Proteomics. 2013 Aug 26;89:51-70.
Title: Quantitative secretome analysis reveals the interactions between epithelia and tumor cells by in vitro modulating colon cancer microenvironment.
Author: Zeng, Xiao|Yang, Pengbo|Chen, Bing|Jin, Xuewen|Liu, Yuling|Zhao, Xia|Liang, Shufang
PMID: 23748022
Journal: Mol Cancer Ther. 2015 Feb;14(2):620-30.
Title: IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
Author: Huang, Fei|Chang, Han|Greer, Ann|Hillerman, Stephen|Reeves, Karen A|Hurlburt, Warren|Cogswell, John|Patel, Dharmesh|Qi, Zhenhao|Fairchild, Craig|Ryseck, Rolf-Peter|Wong, Tai W|Finckenstein, Friedrich G|Jackson, Jeffrey|Carboni, Joan M
PMID: 25527633
Journal: Med Sci Monit. 2016 Mar 15;22:848-54.
Title: Correlation Between IGFs-Related Proteins Expression and Incidence of Colorectal Cancer in Diabetic Patients and Related Mechanisms.
Author: Han, Xu|Hou, Sufang|Yang, Aige
PMID: 26976474
Journal: Asian Pac J Cancer Prev. 2016;17(8):3963-9.
Title: Association of IGFBP-6 Expression with Metabolic Syndrome and Adiponectin and IGF-IR Receptor Levels in Colorectal Cancer.
Author: Yunusova, Natalia V|Spirina, Liudmila V|Frolova, Alena E|Afanas'ev, Sergey G|Kolegova, Elena S|Kondakova, Irina V
PMID: 27644646
Journal: Cancer Biomark. 2018;21(4):893-898.
Title: Correlation of IGFBP-6 expression with apoptosis and migration of colorectal carcinoma cells.
Author: Qiu, Fei|Gao, Wei|Wang, Bin
PMID: 29439316