Primary Site >> Stomach Cancer

Gene >> IGF2

Journal: Int J Cancer. 1989 Dec 15;44(6):1100-3.
Title: A new gastric carcinoma cell line (LIM1839) derived from a young Caucasian male.
Author: Whitehead, R H|Novak, U|Thomas, R J|Lukeis, R E|Walker, F E|Jones, J
PMID: 2606577
Journal: Endocrinology. 1990 Jun;126(6):3033-42.
Title: Autocrine regulation of human tumor cell proliferation by insulin-like growth factor II: an in-vitro model.
Author: Thompson, M A|Cox, A J|Whitehead, R H|Jonas, H A
PMID: 1693565
Journal: Eur J Surg Oncol. 1991 Jun;17(3):276-80.
Title: Increased production of growth factors and epidermal growth factor receptor by gastric carcinoma.
Author: Paterson, I M|Bennett, C A|Corbishley, C M|Luqmani, Y
PMID: 2044780
Journal: Gan To Kagaku Ryoho. 1994 Oct;21(14):2371-7.
Title: [Genetic characteristics of scirrhous gastric carcinomas].
Author: Yokozaki, H|Kuniyasu, H|Yasui, W|Tahara, E
PMID: 7944479
Journal: Virchows Arch. 1994;424(4):449-52.
Title: Expression of insulin-like growth factor II by a gastric carcinoma associated with hypoglycaemia.
Author: Horiuchi, T|Shinohara, Y|Sakamoto, Y|Hizuka, N|Watabe, T|Mokuda, O|Tanaka, K|Shimizu, N|Sugano, I|Nagao, K
PMID: 8205358
Journal: J Korean Med Sci. 1997 Feb;12(1):32-9.
Title: Serum insulin-like growth factors (IGFs) and IGF binding protein (IGFBP)-3 in patients with gastric cancer: IGFBP-3 protease activity induced by surgery.
Author: Lee, D Y|Yang, D H|Kang, C W|Kim, S J|Joo, C U|Cho, S C|Kim, J S
PMID: 9142657
Journal: Cancer Lett. 1997 Nov 25;120(1):9-14.
Title: Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma.
Author: Wu, M S|Wang, H P|Lin, C C|Sheu, J C|Shun, C T|Lee, W J|Lin, J T
PMID: 9570380
Journal: Int J Oncol. 1998 Sep;13(3):519-23.
Title: Expression of insulin-like growth factor 2 mRNA in human gastric cancer.
Author: Shiraishi, T|Mori, M|Yamagata, M|Haraguchi, M|Ueo, H|Sugimachi, K
PMID: 9683787
Journal: Cancer Res. 1998 Nov 1;58(21):4802-4.
Title: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Author: Zou, T|Fleisher, A S|Kong, D|Yin, J|Souza, R F|Wang, S|Smolinski, K N|Abraham, J M|Meltzer, S J
PMID: 9809981
Journal: Eur J Cancer. 2001 Nov;37(17):2257-63.
Title: Expression of the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs) in human gastric cancer cells.
Author: Yi, H K|Hwang, P H|Yang, D H|Kang, C W|Lee, D Y
PMID: 11677116
Journal: Hepatogastroenterology. 2001 Nov-Dec;48(42):1788-92.
Title: Expression of insulin-like growth factor-2, c-MET, matrix metalloproteinase-7 and MUC-1 in primary lesions and lymph node metastatic lesions of gastric cancer.
Author: Ajisaka, H|Fushida, S|Yonemura, Y|Miwa, K
PMID: 11813625
Journal: Biochem Biophys Res Commun. 2002 Jun 7;294(2):480-6.
Title: Enhanced expression of insulin-like growth factor binding protein-3 sensitizes the growth inhibitory effect of anticancer drugs in gastric cancer cells.
Author: Lee, Dae-Yeol|Yi, Ho Keun|Hwang, Pyoung Han|Oh, Youngman
PMID: 12051736
Journal: Oncogene. 2002 Jul 25;21(32):5006-15.
Title: Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Author: Soo Hoo, Linda|Zhang, Jianying Y|Chan, Edward K L
PMID: 12118381
Journal: J Pathol. 2003 Nov;201(3):430-8.
Title: Gastric cancer: the role of insulin-like growth factor 2 (IGF 2) and its receptors (IGF 1R and M6-P/IGF 2R).
Author: Pavelic, Kresimir|Kolak, Toni|Kapitanovic, Sanja|Radosevic, Senka|Spaventi, Sime|Kruslin, Bozo|Pavelic, Jasminka
PMID: 14595755
Journal: Intern Med. 2004 Sep;43(9):824-8.
Title: Severe hypoglycemia and hypokalemia in association with liver metastases of gastric cancer.
Author: Kato, Akihiko|Bando, Etsuro|Shinozaki, Shingo|Yonemura, Yutaka|Aiba, Motohiko|Fukuda, Izumi|Hizuka, Naomi|Kameya, Toru
PMID: 15497518
Journal: Zhonghua Zhong Liu Za Zhi. 2004 Nov;26(11):673-7.
Title: [mRNA expression of IGF-IIand HGF in relation to microvascular density, tumor progression and prognosis of gastric carcinoma].
Author: Zhao, Zhong-sheng|Ru, Guo-qing|Ma, Jie
PMID: 15777506
Journal: Yi Chuan. 2004 Sep;26(5):574-8.
Title: [DHPLC analysis of microsatellite instability in gastric cancer].
Author: Lu, Bing-Jian|Lai, Mao-De|Cheng, Lei|Zhang, Yu-Wei
PMID: 15640064
Journal: Int J Oncol. 2004 Nov;25(5):1273-8.
Title: Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers.
Author: Sasamoto, Hiromi|Nagasaka, Takeshi|Notohara, Kenji|Ozaki, Kazuhide|Isozaki, Hiroshi|Tanaka, Noriaki|Matsubara, Nagahide
PMID: 15492815
Journal: Int J Biochem Cell Biol. 2005 Mar;37(3):616-27.
Title: Effect of all-trans-retinoic acid on mRNA binding protein p62 in human gastric cancer cells.
Author: Ping, Shi|Wang, Sanying|Zhang, Jianying|Peng, Xuanxian
PMID: 15618018
Journal: Cell Biol Int. 2005 Feb;29(2):127-31.
Title: Effects of ATRA on expression of mRNA binding protein p62 in human gastric cancer cells.
Author: Shi, Ping|Huang, Zhiwei|Wang, Sanying|Zhang, Jianying|Peng, Xuanxian
PMID: 15774309
Journal: Biochem Biophys Res Commun. 2005 May 13;330(3):760-7.
Title: Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
Author: Yi, Ho-Keun|Kim, Sun-Young|Hwang, Pyoung-Han|Kim, Chan-Young|Yang, Doo-Hyun|Oh, Youngman|Lee, Dae-Yeol
PMID: 15809062
Journal: Gut. 2005 May;54(5):591-600.
Title: Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.
Author: Min, Y|Adachi, Y|Yamamoto, H|Imsumran, A|Arimura, Y|Endo, T|Hinoda, Y|Lee, C-T|Nadaf, S|Carbone, D P|Imai, K
PMID: 15831900
Journal: J Epidemiol. 2005 Jun;15 Suppl 2:S120-5.
Title: Serum levels of insulin-like growth factor I, II, and binding protein 3, transforming growth factor beta-1, soluble fas ligand and superoxide dismutase activity in stomach cancer cases and their controls in the JACC Study.
Author: Yatsuya, Hiroshi|Toyoshima, Hideaki|Tamakoshi, Koji|Tamakoshi, Akiko|Kondo, Takaaki|Hayakawa, Norihiko|Sakata, Kiyomi|Kikuchi, Shogo|Hoshiyama, Yoshiharu|Fujino, Yoshihisa|Mizoue, Tetsuya|Tokui, Noritaka|Yoshimura, Takesumi
PMID: 16127223
Journal: Exp Mol Med. 2005 Oct 31;37(5):391-8.
Title: PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells.
Author: Hwang, Pyoung Han|Kim, Sun Young|Lee, Jung Chang|Kim, Sun Jun|Yi, Ho Keun|Lee, Dae Yeol
PMID: 16264263
Journal: J Surg Oncol. 2006 Aug 1;94(2):149-54.
Title: Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas.
Author: Mizokami, Ken|Kakeji, Yoshihiro|Oda, Shinya|Irie, Koji|Yonemura, Tomohiro|Konishi, Fumio|Maehara, Yoshihiko
PMID: 16847924
Journal: Growth Horm IGF Res. 2006 Aug;16(4):211-6.
Title: Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia.
Author: Fukuda, Izumi|Hizuka, Naomi|Ishikawa, Yukiko|Yasumoto, Kumiko|Murakami, Yuko|Sata, Akira|Morita, Junko|Kurimoto, Makiko|Okubo, Yumiko|Takano, Kazue
PMID: 16860583
Journal: Clin Exp Med. 2007 Sep;7(3):98-101. Epub 2007 Oct 3.
Title: Association of gastric cancer with tyrosine hydroxylase gene polymorphism in a northwestern Chinese population.
Author: Li, Z Q|Yu, W P|Xie, X D|Li, P Q|Guo, T K|Zhang, W H|An, L Z|Wang, X L
PMID: 17972051
Journal: Zhonghua Wai Ke Za Zhi. 2007 Jul 1;45(13):905-8.
Title: [Expressions of hypoxia inducible factor-1alpha and insulin-like growth factor-II in gastric carcinoma: correlation with angiogenesis and prognosis].
Author: Ru, Guo-Qing|Zhao, Zhong-Sheng|Tang, Qi-le|Xu, Wen-Juan
PMID: 17953839
Journal: Dig Dis Sci. 2007 Jan;52(1):248-53. Epub 2006 Dec 15.
Title: Expression of IGFBP2 in gastric carcinoma and relationship with clinicopathologic parameters and cell proliferation.
Author: Zhang, Lihua|Huang, Wenbin|Chen, Jieyu|Zhou, Xiaojun|Lu, Zhenfeng|Zhou, Hangbo
PMID: 17171534
Journal: Eur J Cancer. 2007 Jul;43(10):1611-6.
Title: A nested case-control study of stomach cancer and serum insulin-like growth factor (IGF)-1, IGF-2 and IGF-binding protein (IGFBP)-3.
Author: Pham, Truong-Minh|Fujino, Yoshihisa|Kikuchi, Shogo|Tamakoshi, Akiko|Yatsuya, Hiroshi|Matsuda, Shinya|Yoshimura, Takesumi
PMID: 17532620
Journal: Lab Invest. 2008 Feb;88(2):161-70.
Title: DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
Author: Kang, Gyeong Hoon|Lee, Sun|Cho, Nam-Yun|Gandamihardja, Tasha|Long, Tiffany I|Weisenberger, Daniel J|Campan, Mihaela|Laird, Peter W
PMID: 18158559
Journal: Mol Cell Biol. 2009 Jan;29(2):402-13.
Title: A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis.
Author: Tanaka, Masamitsu|Sasaki, Kazuki|Kamata, Reiko|Hoshino, Yukari|Yanagihara, Kazuyoshi|Sakai, Ryuichi
PMID: 19015244
Journal: Pathol Oncol Res. 2009 Dec;15(4):589-96.
Title: Prognostic value of tumor-related molecular expression in gastric carcinoma.
Author: Zhao, Zhong-Sheng|Wang, Yuan-Yu|Ye, Zai-Yuan|Tao, Hou-Quan
PMID: 19294533
Journal: Int J Cancer. 2009 Dec 1;125(11):2673-8.
Title: IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.
Author: Hoyo, Cathrine|Schildkraut, Joellen M|Murphy, Susan K|Chow, Wong-Ho|Vaughan, Thomas L|Risch, Harvey|Marks, Jeffrey R|Jirtle, Randy L|Calingaert, Brian|Mayne, Susan|Fraumeni, Joseph Jr|Gammon, Marilie D
PMID: 19626700
Journal: J Exp Clin Cancer Res. 2009 Sep 9;28:125.
Title: Loss of imprinting of insulin-like growth factor 2 is associated with increased risk of lymph node metastasis and gastric corpus cancer.
Author: Lu, Yang|Lu, Ping|Zhu, Zhi|Xu, Huimian|Zhu, Xike
PMID: 19737423
Journal: Asian Pac J Cancer Prev. 2009 Dec;10 Suppl:1-5.
Title: Selection of cases and controls for the nested case-control study within the Japan Collaborative Cohort Study: the First-wave.
Author: Tamakoshi, Akiko|Suzuki, Koji|Ito, Yoshinori|Watanabe, Yoshiyuki|Inaba, Yutaka|Tajima, Kazuo|Nakachi, Kei|Ohno, Yohiyuki
PMID: 20553075
Journal: Pathol Int. 2010 Aug;60(8):595-7.
Title: A case of gastric cancer with non-islet cell tumor hypoglycemia detected by insulin-like growth factor II.
Author: Maruyama, Hiroshi|Tatsumi, Mitsutoshi|Kitayama, Hitoshi|Enomoto, Yasunori|Kuniyasu, Hiroki|Uematsu, Kunio|Fukuda, Izumi|Kameya, Toru|Konishi, Yoichi
PMID: 20618739
Journal: Mol Carcinog. 2011 May;50(5):390-6.
Title: Loss of imprinting and abnormal expression of the insulin-like growth factor 2 gene in gastric cancer.
Author: Zuo, Qing-Song|Yan, Ronglin|Feng, Dian-Xu|Zhao, Ronghua|Chen, Chao|Jiang, Yi-Ming|Cruz-Correa, Marcia|Casson, Alan G|Kang, Xiang-Dong|Han, Feng|Chen, Teng
PMID: 21268128
Journal: Clin J Gastroenterol. 2011 Apr;4(2):68-72.
Title: Severe hypoglycemia associated with insulin-like growth factor II-producing liver metastasis from gastric carcinoma treated with overnight total parenteral nutrition via a central vein catheter reserve port.
Author: Koizumi, Yohei|Hiraoka, Atsushi|Michitaka, Kojiro|Tazuya, Nayu|Ichiryu, Misa|Nakahara, Hiromasa|Ochi, Hironori|Tanabe, Atsushi|Hidaka, Satoshi|Kodama, Akihiro|Uehara, Takahide|Hasebe, Aki|Miyamoto, Yasunao|Ninomiya, Tomoyuki|Kumagi, Teru|Abe, Masanori|Mat
PMID: 26190708
Journal: Int J Cancer. 2012 Dec 1;131(11):2596-603.
Title: Insulin-like growth factor 2 hypomethylation of blood leukocyte DNA is associated with gastric cancer risk.
Author: Yuasa, Yasuhito|Nagasaki, Hiromi|Oze, Isao|Akiyama, Yoshimitsu|Yoshida, Shunsuke|Shitara, Kouhei|Ito, Seiji|Hosono, Satoyo|Watanabe, Miki|Ito, Hidemi|Tanaka, Hideo|Kang, Daehee|Pan, Kai-Feng|You, Wei-Cheng|Matsuo, Keitaro
PMID: 22447362
Journal: Carcinogenesis. 2012 Aug;33(8):1553-62.
Title: Release of TGFbetaig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression.
Author: Holmberg, Chris|Quante, Michael|Steele, Islay|Kumar, Jothi Dinesh|Balabanova, Silviya|Duval, Cedric|Czepan, Matyas|Rakonczay, Zoltan Jr|Tiszlavicz, Laszlo|Nemeth, Istvan|Lazar, Gyorgy|Simonka, Zsolt|Jenkins, Rosalind|Hegyi, Peter|Wang, Timothy C|Dockray,
PMID: 22610072
Journal: Nihon Rinsho. 2012 May;70(5):749-53.
Title: [Epigenomic markers for tumors].
Author: Kaneda, Atsushi
PMID: 22619996
Journal: Intern Med. 2013;52(7):757-60. Epub 2013 Apr 1.
Title: Gastric neuroendocrine carcinoma with non-islet cell tumor hypoglycemia associated with enhanced production of insulin-like growth factor II.
Author: Ida, Tomonori|Morohashi, Taiki|Ohara, Hiroshi|Goto, Toru|Inamori, Masahiko|Nakajima, Atsushi|Maeda, Shin|Tsukumo, Yoko|Sakamoto, Atsuhiko|Ishikawa, Yukio
PMID: 23545670
Journal: Case Rep Gastrointest Med. 2013;2013:148761.
Title: A novel case of functional gastric neuroendocrine carcinoma occurred after endoscopic submucosal dissection.
Author: Shibata, Yoshiaki|Ito, Yuji|Fujita, Hiroko|Okada, Yume|Nagai, Toshihiko|Sano, Hirohito|Ito, Kumiko
PMID: 24307956
Journal: Cancer Prev Res (Phila). 2013 Oct;6(10):1093-100.
Title: Examination of whole blood DNA methylation as a potential risk marker for gastric cancer.
Author: Tahara, Tomomitsu|Maegawa, Shinji|Chung, Woonbok|Garriga, Judith|Jelinek, Jaroslav|Estecio, Marcos R H|Shibata, Tomoyuki|Hirata, Ichiro|Arisawa, Tomiyasu|Issa, Jean-Pierre J
PMID: 23943784
Journal: Turk J Gastroenterol. 2013;24(2):99-108.
Title: Expression and significance of IGF-2, PCNA, MMP-7, and alpha-actin in gastric carcinoma with Lauren classification.
Author: Kuang, Rong-Guang|Wu, Heng-Xiang|Hao, Guo-Xiang|Wang, Jian-Wen|Zhou, Cheng-Jun
PMID: 23934455
Journal: Chin Med J (Engl). 2014;127(3):412-6.
Title: Role of polymorphisms of the IGF2 and IGFBP3 genes and risk of gastric carcinoma in China.
Author: Gu, Jun|Li, Maolan|Dong, Ping|Lu, Jianhua|Tan, Zhujun|Wu, Xiangsong|Mu, Jiasheng|Zhang, Lin|Wu, Wenguang|Ding, Qichen|Yang, Jiahua|Cao, Yang|Ding, Qian|Weng, Hao|Liu, Yingbin
PMID: 24451943
Journal: Carcinogenesis. 2014 Aug;35(8):1798-806.
Title: The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression.
Author: Balabanova, Silvia|Holmberg, Chris|Steele, Islay|Ebrahimi, Bahram|Rainbow, Lucille|Burdyga, Ted|McCaig, Cathy|Tiszlavicz, Lazso|Lertkowit, Nantaporn|Giger, Olivier T|Oliver, Simon|Prior, Ian|Dimaline, Rod|Simpson, Deborah|Beynon, Rob|Hegyi, Peter|Wang, Ti
PMID: 24710625
Journal: Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):2019-26.
Title: Methylation status of blood leukocyte DNA and risk of gastric cancer in a high-risk Chinese population.
Author: Zhang, Yang|Su, Hui-Juan|Pan, Kai-Feng|Zhang, Lian|Ma, Jun-Ling|Shen, Lin|Li, Ji-You|Liu, Wei-Dong|Oze, Isao|Matsuo, Keitaro|Yuasa, Yasuhito|You, Wei-Cheng
PMID: 25086101
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Oct;18(10):1047-50.
Title: [Analysis of gastric cancer tissues genome methylation by DNA methylation chip].
Author: Peng, Tao|Yang, Yongjiang|Zhao, Yifeng|Gao, Jianchao|Abbas, Muhammad|Wang, Guoqiang|Sun, Hong|Li, Shuguang
PMID: 26499154
Journal: J Neurol Surg A Cent Eur Neurosurg. 2016 May;77(3):247-57.
Title: Hemoglobins, Hemorphins, and 11p15.5 Chromosomal Region in Cancer Biology and Immunity with Special Emphasis for Brain Tumors.
Author: Altinoz, Meric Adil|Elmaci, Ilhan|Ince, Bahri|Ozpinar, Aysel|Sav, Aydin Murat
PMID: 26935297
Journal: Exp Clin Endocrinol Diabetes. 2017 Jun;125(6):392-399.
Title: Metformin Inhibits N-Methyl-N-Nitrosourea Induced Gastric Tumorigenesis in db/db Mice.
Author: Zhuang, Shan|Jian, Yongmei|Sun, Yongning
PMID: 28407669
Journal: Clin Exp Med. 2018 May;18(2):215-220.
Title: Methylation status of IGF2 DMR and LINE1 in leukocyte DNA provides distinct clinicopathological features of gastric cancer patients.
Author: Tahara, Tomomitsu|Tahara, Sayumi|Horiguchi, Noriyuki|Kawamura, Tomohiko|Okubo, Masaaki|Yamada, Hyuga|Yoshida, Dai|Ohmori, Takafumi|Maeda, Kohei|Komura, Naruomi|Ikuno, Hirokazu|Jodai, Yasutaka|Kamano, Toshiaki|Nagasaka, Mitsuo|Nakagawa, Yoshihito|Tsukamoto
PMID: 28871451
Journal: J Cell Biochem. 2018 Jun 28.
Title: Silencing forkhead box M1 promotes apoptosis and autophagy through SIRT7/mTOR/IGF2 pathway in gastric cancer cells.
Author: Yu, Wei|Cui, Xiaofeng|Wan, Zhongyi|Yu, Yanhui|Liu, Xiumin|Jin, Lifang
PMID: 29953672
Journal:
Title: Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1.
Author:
PMID: 29983893
Journal: Int J Mol Sci. 2018 Aug 15;19(8). pii: ijms19082411.
Title: Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers.
Author: Cevenini, Armando|Orru, Stefania|Mancini, Annamaria|Alfieri, Andreina|Buono, Pasqualina|Imperlini, Esther
PMID: 30111747