Primary Site >> Pancreatic Cancer

Gene >> IDO1

Journal: J Am Coll Surg. 2008 May;206(5):849-54; discussion 854-6.
Title: Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection.
Author: Witkiewicz, Agnes|Williams, Timothy K|Cozzitorto, Joseph|Durkan, Brandice|Showalter, Shayna L|Yeo, Charles J|Brody, Jonathan R
PMID: 18471709
Journal: J Immunol. 2008 Sep 1;181(5):3116-25.
Title: MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma.
Author: Tinder, Teresa L|Subramani, Durai B|Basu, Gargi D|Bradley, Judy M|Schettini, Jorge|Million, Arefayene|Skaar, Todd|Mukherjee, Pinku
PMID: 18713982
Journal: Mol Cancer Ther. 2010 Feb;9(2):489-98.
Title: Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors.
Author: Koblish, Holly K|Hansbury, Michael J|Bowman, Kevin J|Yang, Gengjie|Neilan, Claire L|Haley, Patrick J|Burn, Timothy C|Waeltz, Paul|Sparks, Richard B|Yue, Eddy W|Combs, Andrew P|Scherle, Peggy A|Vaddi, Kris|Fridman, Jordan S
PMID: 20124451
Journal: Pancreatology. 2010;10(5):631-40.
Title: FOXP3+ regulatory T cells and tumoral indoleamine 2,3-dioxygenase expression predicts the carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.
Author: Kobayashi, Noritoshi|Kubota, Kensuke|Kato, Shingo|Watanabe, Seitaro|Shimamura, Takeshi|Kirikoshi, Hiroyuki|Saito, Satoru|Ueda, Michio|Endo, Itaru|Inayama, Yoshiaki|Maeda, Shin|Nakajima, Atsushi
PMID: 21051918
Journal: Cancer Res. 2011 Mar 15;71(6):2038-44.
Title: Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2.
Author: Sorensen, Rikke Baek|Kollgaard, Tania|Andersen, Rikke Sick|van den Berg, Joost Huibert|Svane, Inge Marie|Straten, Per thor|Andersen, Mads Hald
PMID: 21406395
Journal: Bioorg Med Chem Lett. 2012 Dec 15;22(24):7641-6.
Title: Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Author: Bakmiwewa, Supun M|Fatokun, Amos A|Tran, Anh|Payne, Richard J|Hunt, Nicholas H|Ball, Helen J
PMID: 23122865
Journal: BMC Cancer. 2014 Oct 2;14:738.
Title: Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction.
Author: Peng, Yun-Peng|Zhang, Jing-Jing|Liang, Wen-biao|Tu, Min|Lu, Zi-Peng|Wei, Ji-Shu|Jiang, Kui-Rong|Gao, Wen-Tao|Wu, Jun-Li|Xu, Ze-Kuan|Miao, Yi|Zhu, Yi
PMID: 25274283
Journal: Cancer Immunol Res. 2015 Sep;3(9):1096-107.
Title: Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors.
Author: Manuel, Edwin R|Chen, Jeremy|D'Apuzzo, Massimo|Lampa, Melanie G|Kaltcheva, Teodora I|Thompson, Curtis B|Ludwig, Thomas|Chung, Vincent|Diamond, Don J
PMID: 26134178
Journal: Chin Med J (Engl). 2017 Mar 20;130(6):710-716.
Title: Expression and Prognostic Value of Indoleamine 2,3-dioxygenase in Pancreatic Cancer.
Author: Zhang, Tao|Tan, Xiang-Long|Xu, Yong|Wang, Zi-Zheng|Xiao, Chao-Hui|Liu, Rong
PMID: 28303855
Journal: Int J Cancer. 2017 Aug 1;141(3):572-582.
Title: Tumor cell expression of immune inhibitory molecules and tumor-infiltrating lymphocyte count predict cancer-specific survival in pancreatic and ampullary cancer.
Author: Sideras, Kostandinos|Biermann, Katharina|Yap, Kevin|Mancham, Shanta|Boor, Patrick P C|Hansen, Bettina E|Stoop, Hans J A|Peppelenbosch, Maikel P|van Eijck, Casper H|Sleijfer, Stefan|Kwekkeboom, Jaap|Bruno, Marco J
PMID: 28470686
Journal: Biochem J. 2017 Sep 28;474(20):3391-3402.
Title: Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy.
Author: Ogura, Jiro|Miyauchi, Seiji|Shimono, Kazumi|Yang, Shengping|Gonchigar, Sathisha|Ganapathy, Vadivel|Bhutia, Yangzom D
PMID: 28963435
Journal: Nat Commun. 2017 Nov 27;8(1):1811.
Title: Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression.
Author: Lu, Jianqin|Liu, Xiangsheng|Liao, Yu-Pei|Salazar, Felix|Sun, Bingbing|Jiang, Wen|Chang, Chong Hyun|Jiang, Jinhong|Wang, Xiang|Wu, Anna M|Meng, Huan|Nel, Andre E
PMID: 29180759
Journal: Cancer Discov. 2018 Jul;8(7):OF5.
Title: Companies Scaling Back IDO1 Inhibitor Trials.
Author:
PMID: 29848606
Journal: Pathol Res Pract. 2018 Sep;214(9):1309-1314.
Title: Indoleamine 2, 3-dioxygenase and B7-H1 expressions as prognostic and follow-up markers in human pancreatic carcinoma.
Author: Wang, Liancai|Ma, Qingyong|Li, Deyu|Mu, Senmao|Li, Yong|Wang, Yafeng|Shi, Pengfei|Yu, Haibo|Gao, Chunhui|Guo, Kun|Zhang, Zhuoli
PMID: 30029936