Primary Site >> Biliary tract Cancer
Gene >> IDH1
| 1. | |||||||||||
| Journal: | Oncologist. 2012;17(1):72-9. | ||||||||||
| Title: | Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. | ||||||||||
| Author: | Borger, Darrell R|Tanabe, Kenneth K|Fan, Kenneth C|Lopez, Hector U|Fantin, Valeria R|Straley, Kimberly S|Schenkein, David P|Hezel, Aram F|Ancukiewicz, Marek|Liebman, Hannah M|Kwak, Eunice L|Clark, Jeffrey W|Ryan, David P|Deshpande, Vikram|Dias-Santagata, | ||||||||||
| PMID: | 22180306 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2013 Jun 20;32(25):3091-100. | ||||||||||
| Title: | Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. | ||||||||||
| Author: | Wang, P|Dong, Q|Zhang, C|Kuan, P-F|Liu, Y|Jeck, W R|Andersen, J B|Jiang, W|Savich, G L|Tan, T-X|Auman, J T|Hoskins, J M|Misher, A D|Moser, C D|Yourstone, S M|Kim, J W|Cibulskis, K|Getz, G|Hunt, H V|Thorgeirsson, S S|Roberts, L R|Ye, D|Guan, K-L|Xiong, Y|Q | ||||||||||
| PMID: | 22824796 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2013 Oct 10;32(41):4861-70. | ||||||||||
| Title: | Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. | ||||||||||
| Author: | Sia, D|Tovar, V|Moeini, A|Llovet, J M | ||||||||||
| PMID: | 23318457 | ||||||||||
| 4. | |||||||||||
| Journal: | Hum Pathol. 2013 Jul;44(7):1216-22. | ||||||||||
| Title: | Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. | ||||||||||
| Author: | Voss, Jesse S|Holtegaard, Leonard M|Kerr, Sarah E|Fritcher, Emily G Barr|Roberts, Lewis R|Gores, Gregory J|Zhang, Jun|Highsmith, W Edward|Halling, Kevin C|Kipp, Benjamin R | ||||||||||
| PMID: | 23391413 | ||||||||||
| 5. | |||||||||||
| Journal: | Nat Genet. 2013 Dec;45(12):1474-8. | ||||||||||
| Title: | Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. | ||||||||||
| Author: | Chan-On, Waraporn|Nairismagi, Maarja-Liisa|Ong, Choon Kiat|Lim, Weng Khong|Dima, Simona|Pairojkul, Chawalit|Lim, Kiat Hon|McPherson, John R|Cutcutache, Ioana|Heng, Hong Lee|Ooi, London|Chung, Alexander|Chow, Pierce|Cheow, Peng Chung|Lee, Ser Yee|Choo, Su | ||||||||||
| PMID: | 24185513 | ||||||||||
| 6. | |||||||||||
| Journal: | Biochim Biophys Acta. 2014 Dec;1846(2):326-41. | ||||||||||
| Title: | The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation. | ||||||||||
| Author: | Molenaar, Remco J|Radivoyevitch, Tomas|Maciejewski, Jaroslaw P|van Noorden, Cornelis J F|Bleeker, Fonnet E | ||||||||||
| PMID: | 24880135 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2014 Dec 23;9(12):e115383. | ||||||||||
| Title: | Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications. | ||||||||||
| Author: | Churi, Chaitanya R|Shroff, Rachna|Wang, Ying|Rashid, Asif|Kang, HyunSeon C|Weatherly, Jacqueline|Zuo, Mingxin|Zinner, Ralph|Hong, David|Meric-Bernstam, Funda|Janku, Filip|Crane, Christopher H|Mishra, Lopa|Vauthey, Jean-Nicholas|Wolff, Robert A|Mills, Gord | ||||||||||
| PMID: | 25536104 | ||||||||||
| 8. | |||||||||||
| Journal: | Nat Commun. 2014 Dec 15;5:5696. | ||||||||||
| Title: | Mutational landscape of intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Zou, Shanshan|Li, Jiarui|Zhou, Huabang|Frech, Christian|Jiang, Xiaolan|Chu, Jeffrey S C|Zhao, Xinyin|Li, Yuqiong|Li, Qiaomei|Wang, Hui|Hu, Jingyi|Kong, Guanyi|Wu, Mengchao|Ding, Chuanfan|Chen, Nansheng|Hu, Heping | ||||||||||
| PMID: | 25526346 | ||||||||||
| 9. | |||||||||||
| Journal: | Cell Cycle. 2014;13(20):3176-82. | ||||||||||
| Title: | IDH mutations in liver cell plasticity and biliary cancer. | ||||||||||
| Author: | Saha, Supriya K|Parachoniak, Christine A|Bardeesy, Nabeel | ||||||||||
| PMID: | 25485496 | ||||||||||
| 10. | |||||||||||
| Journal: | Semin Liver Dis. 2014 Nov;34(4):456-64. | ||||||||||
| Title: | Cholangiocarcinoma: molecular pathways and therapeutic opportunities. | ||||||||||
| Author: | Rizvi, Sumera|Borad, Mitesh J|Patel, Tushar|Gores, Gregory J | ||||||||||
| PMID: | 25369307 | ||||||||||
| 11. | |||||||||||
| Journal: | Nature. 2014 Sep 4;513(7516):110-4. | ||||||||||
| Title: | Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer. | ||||||||||
| Author: | Saha, Supriya K|Parachoniak, Christine A|Ghanta, Krishna S|Fitamant, Julien|Ross, Kenneth N|Najem, Mortada S|Gurumurthy, Sushma|Akbay, Esra A|Sia, Daniela|Cornella, Helena|Miltiadous, Oriana|Walesky, Chad|Deshpande, Vikram|Zhu, Andrew X|Hezel, Aram F|Yen, | ||||||||||
| PMID: | 25043045 | ||||||||||
| 12. | |||||||||||
| Journal: | Ann Surg Oncol. 2014 Nov;21(12):3827-34. | ||||||||||
| Title: | Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets. | ||||||||||
| Author: | Zhu, Andrew X|Borger, Darrell R|Kim, Yuhree|Cosgrove, David|Ejaz, Aslam|Alexandrescu, Sorin|Groeschl, Ryan Thomas|Deshpande, Vikram|Lindberg, James M|Ferrone, Cristina|Sempoux, Christine|Yau, Thomas|Poon, Ronnie|Popescu, Irinel|Bauer, Todd W|Gamblin, T Cl | ||||||||||
| PMID: | 24889489 | ||||||||||
| 13. | |||||||||||
| Journal: | Curr Opin Gastroenterol. 2014 May;30(3):295-302. | ||||||||||
| Title: | Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Grassian, Alexandra R|Pagliarini, Raymond|Chiang, Derek Y | ||||||||||
| PMID: | 24569570 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncologist. 2014 Mar;19(3):235-42. | ||||||||||
| Title: | New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. | ||||||||||
| Author: | Ross, Jeffrey S|Wang, Kai|Gay, Laurie|Al-Rohil, Rami|Rand, Janne V|Jones, David M|Lee, Hwa J|Sheehan, Christine E|Otto, Geoff A|Palmer, Gary|Yelensky, Roman|Lipson, Doron|Morosini, Deborah|Hawryluk, Matthew|Catenacci, Daniel V T|Miller, Vincent A|Churi, C | ||||||||||
| PMID: | 24563076 | ||||||||||
| 15. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):380-7. | ||||||||||
| Title: | Genomic and transcriptional alterations of cholangiocarcinoma. | ||||||||||
| Author: | Ito, Takeshi|Sakurai-Yageta, Mika|Goto, Akiteru|Pairojkul, Chawalit|Yongvanit, Puangrat|Murakami, Yoshinori | ||||||||||
| PMID: | 24532422 | ||||||||||
| 16. | |||||||||||
| Journal: | Clin Cancer Res. 2014 Apr 1;20(7):1884-90. | ||||||||||
| Title: | Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Borger, Darrell R|Goyal, Lipika|Yau, Thomas|Poon, Ronnie T|Ancukiewicz, Marek|Deshpande, Vikram|Christiani, David C|Liebman, Hannah M|Yang, Hua|Kim, Hyeryun|Yen, Katharine|Faris, Jason E|Iafrate, A John|Kwak, Eunice L|Clark, Jeffrey W|Allen, Jill N|Blaszk | ||||||||||
| PMID: | 24478380 | ||||||||||
| 17. | |||||||||||
| Journal: | Mod Pathol. 2014 Aug;27(8):1163-73. | ||||||||||
| Title: | Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features. | ||||||||||
| Author: | Liau, Jau-Yu|Tsai, Jia-Huei|Yuan, Ray-Hwang|Chang, Chih-Ning|Lee, Hsin-Jung|Jeng, Yung-Ming | ||||||||||
| PMID: | 24406866 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncologist. 2015 Sep;20(9):1019-27. | ||||||||||
| Title: | Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma. | ||||||||||
| Author: | Goyal, Lipika|Govindan, Aparna|Sheth, Rahul A|Nardi, Valentina|Blaszkowsky, Lawrence S|Faris, Jason E|Clark, Jeffrey W|Ryan, David P|Kwak, Eunice L|Allen, Jill N|Murphy, Janet E|Saha, Supriya K|Hong, Theodore S|Wo, Jennifer Y|Ferrone, Cristina R|Tanabe, K | ||||||||||
| PMID: | 26245674 | ||||||||||
| 19. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2015;16(14):5875-81. | ||||||||||
| Title: | Altered Expression of Oxidative Metabolism Related Genes in Cholangiocarcinomas. | ||||||||||
| Author: | Aukkanimart, Ratchadawan|Boonmars, Thidarut|Juasook, Amornrat|Sriraj, Pranee|Boonjaraspinyo, Sirintip|Wu, Zhiliang|Laummuanwai, Porntip|Pairojkul, Chawalit|Khuntikeo, Narong|Rattanasuwan, Panaratana | ||||||||||
| PMID: | 26320466 | ||||||||||
| 20. | |||||||||||
| Journal: | Exp Mol Pathol. 2015 Oct;99(2):344-53. | ||||||||||
| Title: | Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay. | ||||||||||
| Author: | Arnold, Alexander|Bahra, Marcus|Lenze, Dido|Bradtmoller, Maren|Guse, Katrin|Gehlhaar, Claire|Blaker, Hendrik|Heppner, Frank L|Koch, Arend | ||||||||||
| PMID: | 26260902 | ||||||||||
| 21. | |||||||||||
| Journal: | Exp Mol Pathol. 2015 Oct;99(2):240-4. | ||||||||||
| Title: | Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing. | ||||||||||
| Author: | Putra, Juan|de Abreu, Francine B|Peterson, Jason D|Pipas, J Marc|Mody, Kabir|Amos, Christopher I|Tsongalis, Gregory J|Suriawinata, Arief A | ||||||||||
| PMID: | 26189129 | ||||||||||
| 22. | |||||||||||
| Journal: | Nat Commun. 2015 Jan 30;6:6120. | ||||||||||
| Title: | Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. | ||||||||||
| Author: | Fujimoto, Akihiro|Furuta, Mayuko|Shiraishi, Yuichi|Gotoh, Kunihito|Kawakami, Yoshiiku|Arihiro, Koji|Nakamura, Toru|Ueno, Masaki|Ariizumi, Shun-ichi|Nguyen, Ha Hai|Shigemizu, Daichi|Abe, Tetsuo|Boroevich, Keith A|Nakano, Kaoru|Sasaki, Aya|Kitada, Rina|Maej | ||||||||||
| PMID: | 25636086 | ||||||||||
| 23. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2015 Feb;22(2):114-23. | ||||||||||
| Title: | Molecular diagnosis of intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Haga, Hiroaki|Patel, Tushar | ||||||||||
| PMID: | 25267595 | ||||||||||
| 24. | |||||||||||
| Journal: | Nat Commun. 2015 Jan 22;6:6087. | ||||||||||
| Title: | Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Sia, Daniela|Losic, Bojan|Moeini, Agrin|Cabellos, Laia|Hao, Ke|Revill, Kate|Bonal, Dennis|Miltiadous, Oriana|Zhang, Zhongyang|Hoshida, Yujin|Cornella, Helena|Castillo-Martin, Mireia|Pinyol, Roser|Kasai, Yumi|Roayaie, Sasan|Thung, Swan N|Fuster, Josep|Schw | ||||||||||
| PMID: | 25608663 | ||||||||||
| 25. | |||||||||||
| Journal: | Hum Pathol. 2015 Feb;46(2):322-6. | ||||||||||
| Title: | Increased plasma d-2-hydroxyglutarate in isocitrate dehydrogenase 2-mutated blastic plasmacytoid dendritic cell neoplasm. | ||||||||||
| Author: | Rakheja, Dinesh|Fuda, Franklin|Vandergriff, Travis|Boriack, Richard|Medeiros, Bruno C|Frankel, Arthur E|Chen, Weina | ||||||||||
| PMID: | 25481493 | ||||||||||
| 26. | |||||||||||
| Journal: | Mod Pathol. 2015 Sep;28(9):1249-64. | ||||||||||
| Title: | Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases. | ||||||||||
| Author: | Schlitter, Anna Melissa|Jang, Kee-Taek|Kloppel, Gunter|Saka, Burcu|Hong, Seung-Mo|Choi, Hyejeong|Offerhaus, George Johan|Hruban, Ralph H|Zen, Yoh|Konukiewitz, Bjorn|Regel, Ivonne|Allgauer, Michael|Balci, Serdar|Basturk, Olca|Reid, Michelle D|Esposito, Ire | ||||||||||
| PMID: | 26111977 | ||||||||||
| 27. | |||||||||||
| Journal: | Pathol Int. 2016 Oct;66(10):578-582. | ||||||||||
| Title: | Immunohistochemistry using monoclonal antibody MsMab-2 is useful to detect IDH1 R132L in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Hayashi, Akimasa|Misumi, Kento|Shibahara, Junji|Kokudo, Norihiro|Kato, Yukinari|Fukayama, Masashi | ||||||||||
| PMID: | 27595804 | ||||||||||
| 28. | |||||||||||
| Journal: | J Gastrointest Oncol. 2016 Dec;7(6):E98-E102. | ||||||||||
| Title: | Impressive response to dual BRAF and MEK inhibition in patients with BRAF mutant intrahepatic cholangiocarcinoma-2 case reports and a brief review. | ||||||||||
| Author: | Lavingia, Viraj|Fakih, Marwan | ||||||||||
| PMID: | 28078132 | ||||||||||
| 29. | |||||||||||
| Journal: | Chin Clin Oncol. 2016 Oct;5(5):65. | ||||||||||
| Title: | Systemic therapy for biliary cancers. | ||||||||||
| Author: | Jordan, Emmet|Abou-Alfa, Ghassan K|Lowery, Maeve A | ||||||||||
| PMID: | 27829278 | ||||||||||
| 30. | |||||||||||
| Journal: | J Gastrointest Oncol. 2016 Oct;7(5):797-803. | ||||||||||
| Title: | Molecular profiling of biliary tract cancer: a target rich disease. | ||||||||||
| Author: | Jain, Apurva|Javle, Milind | ||||||||||
| PMID: | 27747093 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer. 2016 Dec 15;122(24):3838-3847. | ||||||||||
| Title: | Biliary cancer: Utility of next-generation sequencing for clinical management. | ||||||||||
| Author: | Javle, Milind|Bekaii-Saab, Tanios|Jain, Apurva|Wang, Ying|Kelley, Robin Katie|Wang, Kai|Kang, Hyunseon C|Catenacci, Daniel|Ali, Siraj|Krishnan, Sunil|Ahn, Daniel|Bocobo, Andrea Grace|Zuo, Mingxin|Kaseb, Ahmed|Miller, Vincent|Stephens, Philip J|Meric-Berns | ||||||||||
| PMID: | 27622582 | ||||||||||
| 32. | |||||||||||
| Journal: | J Blood Med. 2016 Sep 2;7:171-80. | ||||||||||
| Title: | IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives. | ||||||||||
| Author: | Mondesir, Johanna|Willekens, Christophe|Touat, Mehdi|de Botton, Stephane | ||||||||||
| PMID: | 27621679 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Discov. 2016 Jul;6(7):727-39. | ||||||||||
| Title: | Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma. | ||||||||||
| Author: | Saha, Supriya K|Gordan, John D|Kleinstiver, Benjamin P|Vu, Phuong|Najem, Mortada S|Yeo, Jia-Chi|Shi, Lei|Kato, Yasutaka|Levin, Rebecca S|Webber, James T|Damon, Leah J|Egan, Regina K|Greninger, Patricia|McDermott, Ultan|Garnett, Mathew J|Jenkins, Roger L|R | ||||||||||
| PMID: | 27231123 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 19;7(29):46750-46767. | ||||||||||
| Title: | The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets. | ||||||||||
| Author: | Chong, Dawn Q|Zhu, Andrew X | ||||||||||
| PMID: | 27102149 | ||||||||||
| 35. | |||||||||||
| Journal: | BMC Res Notes. 2016 Feb 27;9:126. | ||||||||||
| Title: | Maffucci syndrome and neoplasms: a case report and review of the literature. | ||||||||||
| Author: | Prokopchuk, Olga|Andres, Stephanie|Becker, Karen|Holzapfel, Konstantin|Hartmann, Daniel|Friess, Helmut | ||||||||||
| PMID: | 26920730 | ||||||||||
| 36. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Apr 15;22(8):1837-42. | ||||||||||
| Title: | Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer. | ||||||||||
| Author: | Clark, Owen|Yen, Katharine|Mellinghoff, Ingo K | ||||||||||
| PMID: | 26819452 | ||||||||||
| 37. | |||||||||||
| Journal: | Ann Surg Oncol. 2016 May;23(5):1699-707. | ||||||||||
| Title: | Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients. | ||||||||||
| Author: | Ruzzenente, Andrea|Fassan, Matteo|Conci, Simone|Simbolo, Michele|Lawlor, Rita T|Pedrazzani, Corrado|Capelli, Paola|D'Onofrio, Mirko|Iacono, Calogero|Scarpa, Aldo|Guglielmi, Alfredo | ||||||||||
| PMID: | 26717940 | ||||||||||
| 38. | |||||||||||
| Journal: | J Clin Pathol. 2016 May;69(5):403-8. | ||||||||||
| Title: | Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets. | ||||||||||
| Author: | Lee, Hwajeong|Wang, Kai|Johnson, Adrienne|Jones, David M|Ali, Siraj M|Elvin, Julia A|Yelensky, Roman|Lipson, Doron|Miller, Vincent A|Stephens, Philip J|Javle, Milind|Ross, Jeffrey S | ||||||||||
| PMID: | 26500333 | ||||||||||
| 39. | |||||||||||
| Journal: | Clin Cancer Res. 2016 Jan 15;22(2):291-300. | ||||||||||
| Title: | Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma. | ||||||||||
| Author: | Moeini, Agrin|Sia, Daniela|Bardeesy, Nabeel|Mazzaferro, Vincenzo|Llovet, Josep M | ||||||||||
| PMID: | 26405193 | ||||||||||
| 40. | |||||||||||
| Journal: | Histopathology. 2017 Apr;70(5):766-774. | ||||||||||
| Title: | Intrahepatic cholangiocarcinoma frequently shows loss of BAP1 and PBRM1 expression, and demonstrates specific clinicopathological and genetic characteristics with BAP1 loss. | ||||||||||
| Author: | Misumi, Kento|Hayashi, Akimasa|Shibahara, Junji|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa, Kiyoshi|Kokudo, Norihiro|Fukayama, Masashi | ||||||||||
| PMID: | 27864835 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Control. 2017 Jul-Sep;24(3):1073274817729241. | ||||||||||
| Title: | Systemic and Adjuvant Therapies for Intrahepatic Cholangiocarcinoma. | ||||||||||
| Author: | Chun, Yun Shin|Javle, Milind | ||||||||||
| PMID: | 28975832 | ||||||||||
| 42. | |||||||||||
| Journal: | Cancer Discov. 2017 Sep;7(9):943-962. | ||||||||||
| Title: | New Horizons for Precision Medicine in Biliary Tract Cancers. | ||||||||||
| Author: | Valle, Juan W|Lamarca, Angela|Goyal, Lipika|Barriuso, Jorge|Zhu, Andrew X | ||||||||||
| PMID: | 28818953 | ||||||||||
| 43. | |||||||||||
| Journal: | J Gastrointest Oncol. 2017 Jun;8(3):430-440. | ||||||||||
| Title: | Current biologics for treatment of biliary tract cancers. | ||||||||||
| Author: | Zhao, Diana Y|Lim, Kian-Huat | ||||||||||
| PMID: | 28736630 | ||||||||||
| 44. | |||||||||||
| Journal: | BMJ Open. 2017 Jun 10;7(6):e014961. | ||||||||||
| Title: | Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours. | ||||||||||
| Author: | Molenaar, Remco J|Coelen, Robert J S|Khurshed, Mohammed|Roos, Eva|Caan, Matthan W A|van Linde, Myra E|Kouwenhoven, Mathilde|Bramer, Jos A M|Bovee, Judith V M G|Mathot, Ron A|Klumpen, Heinz-Josef|van Laarhoven, Hanneke W M|van Noorden, Cornelis J F|Vandert | ||||||||||
| PMID: | 28601826 | ||||||||||
| 45. | |||||||||||
| Journal: | Therap Adv Gastroenterol. 2017 Jun;10(6):507-520. | ||||||||||
| Title: | The potential role of comprehensive genomic profiling to guide targeted therapy for patients with biliary cancer. | ||||||||||
| Author: | Lee, Hwajeong|Ross, Jeffrey S | ||||||||||
| PMID: | 28567120 | ||||||||||
| 46. | |||||||||||
| Journal: | Hum Pathol. 2017 Jun;64:118-127. | ||||||||||
| Title: | Clinicopathological, radiologic, and molecular study of 23 combined hepatocellular-cholangiocarcinomas with stem cell features, cholangiolocellular type. | ||||||||||
| Author: | Chen, Jun|He, Jian|Deng, Min|Wu, Hong-Yan|Shi, Jiong|Mao, Liang|Sun, Qi|Tang, Min|Fan, Xiang-Shan|Qiu, Yu-Dong|Huang, Qin | ||||||||||
| PMID: | 28431889 | ||||||||||
| 47. | |||||||||||
| Journal: | J Hepatol. 2017 Sep;67(3):632-644. | ||||||||||
| Title: | Emerging molecular therapeutic targets for cholangiocarcinoma. | ||||||||||
| Author: | Rizvi, Sumera|Gores, Gregory J | ||||||||||
| PMID: | 28389139 | ||||||||||
| 48. | |||||||||||
| Journal: | Annu Rev Biochem. 2017 Jun 20;86:305-331. | ||||||||||
| Title: | Isocitrate Dehydrogenase Mutation and (R)-2-Hydroxyglutarate: From Basic Discovery to Therapeutics Development. | ||||||||||
| Author: | Dang, Lenny|Su, Shin-San Michael | ||||||||||
| PMID: | 28375741 | ||||||||||
| 49. | |||||||||||
| Journal: | Mod Pathol. 2017 Jul;30(7):986-997. | ||||||||||
| Title: | Dichotomy in intrahepatic cholangiocarcinomas based on histologic similarities to hilar cholangiocarcinomas. | ||||||||||
| Author: | Akita, Masayuki|Fujikura, Kohei|Ajiki, Tetsuo|Fukumoto, Takumi|Otani, Kyoko|Azuma, Takeshi|Itoh, Tomoo|Ku, Yonson|Zen, Yoh | ||||||||||
| PMID: | 28338651 | ||||||||||
| 50. | |||||||||||
| Journal: | Cell Rep. 2017 Mar 14;18(11):2780-2794. | ||||||||||
| Title: | Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. | ||||||||||
| Author: | Farshidfar, Farshad|Zheng, Siyuan|Gingras, Marie-Claude|Newton, Yulia|Shih, Juliann|Robertson, A Gordon|Hinoue, Toshinori|Hoadley, Katherine A|Gibb, Ewan A|Roszik, Jason|Covington, Kyle R|Wu, Chia-Chin|Shinbrot, Eve|Stransky, Nicolas|Hegde, Apurva|Yang, J | ||||||||||
| PMID: | 28297679 | ||||||||||
| 51. | |||||||||||
| Journal: | Acta Neuropathol. 2017 Apr;133(4):629-644. | ||||||||||
| Title: | Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. | ||||||||||
| Author: | Pusch, Stefan|Krausert, Sonja|Fischer, Viktoria|Balss, Jorg|Ott, Martina|Schrimpf, Daniel|Capper, David|Sahm, Felix|Eisel, Jessica|Beck, Ann-Christin|Jugold, Manfred|Eichwald, Viktoria|Kaulfuss, Stefan|Panknin, Olaf|Rehwinkel, Hartmut|Zimmermann, Katja|Hi | ||||||||||
| PMID: | 28124097 | ||||||||||
| 52. | |||||||||||
| Journal: | World J Surg Oncol. 2017 Apr 12;15(1):82. | ||||||||||
| Title: | IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing. | ||||||||||
| Author: | Lee, Jung Hee|Shin, Dong Hoon|Park, Won Young|Shin, Nari|Kim, Ahrong|Lee, Hyun Jung|Kim, Young Keum|Choi, Kyung Un|Kim, Jee Yeon|Yang, Young Il|Lee, Chang Hun|Sol, Mee Young | ||||||||||
| PMID: | 28403884 | ||||||||||
| 53. | |||||||||||
| Journal: | Hum Pathol. 2018 Aug;78:131-137. | ||||||||||
| Title: | Mucinous intrahepatic cholangiocarcinoma: a distinct variant. | ||||||||||
| Author: | Chi, Zhikai|Bhalla, Amarpreet|Saeed, Omer|Cheng, Liang|Curless, Kendra|Wang, Hanlin L|Patil, Deepa T|Lin, Jingmei | ||||||||||
| PMID: | 29698701 | ||||||||||
| 54. | |||||||||||
| Journal: | Oncologist. 2018 Oct 23. pii: theoncologist.2018-0210. | ||||||||||
| Title: | A Case of Metastatic Biliary Tract Cancer Diagnosed Through Identification of an IDH1 Mutation. | ||||||||||
| Author: | Kamath, Suneel Deepak|Lin, Xiaoqi|Kalyan, Aparna | ||||||||||
| PMID: | 30352944 | ||||||||||
| 55. | |||||||||||
| Journal: | Cancer Lett. 2018 Aug 10;429:1-10. | ||||||||||
| Title: | Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation. | ||||||||||
| Author: | Huang, Chiung-Kuei|Iwagami, Yoshifumi|Zou, Jing|Casulli, Sarah|Lu, Shaolei|Nagaoka, Katsuya|Ji, Chengcheng|Ogawa, Kousuke|Cao, Kevin Y|Gao, Jin-Song|Carlson, Rolf I|Wands, Jack R | ||||||||||
| PMID: | 29733964 | ||||||||||
| 56. | |||||||||||
| Journal: | Clin Lab Med. 2018 Jun;38(2):367-384. | ||||||||||
| Title: | Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update. | ||||||||||
| Author: | Zhang, Lei|Bluth, Martin H|Bhalla, Amarpreet | ||||||||||
| PMID: | 29776636 | ||||||||||
| 57. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Sep 1;24(17):4154-4161. | ||||||||||
| Title: | Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention. | ||||||||||
| Author: | Lowery, Maeve A|Ptashkin, Ryan|Jordan, Emmet|Berger, Michael F|Zehir, Ahmet|Capanu, Marinela|Kemeny, Nancy E|O'Reilly, Eileen M|El-Dika, Imane|Jarnagin, William R|Harding, James J|D'Angelica, Michael I|Cercek, Andrea|Hechtman, Jaclyn F|Solit, David B|Schu | ||||||||||
| PMID: | 29848569 | ||||||||||
| 58. | |||||||||||
| Journal: | BMC Genomics. 2018 Jun 5;19(1):440. | ||||||||||
| Title: | Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Peraldo-Neia, C|Ostano, P|Cavalloni, G|Pignochino, Y|Sangiolo, D|De Cecco, L|Marchesi, E|Ribero, D|Scarpa, A|De Rose, A M|Giuliani, A|Calise, F|Raggi, C|Invernizzi, P|Aglietta, M|Chiorino, G|Leone, F | ||||||||||
| PMID: | 29871612 | ||||||||||
| 59. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2018 Aug 1;48(8):703-711. | ||||||||||
| Title: | New developments in systemic therapy for advanced biliary tract cancer. | ||||||||||
| Author: | Morizane, Chigusa|Ueno, Makoto|Ikeda, Masafumi|Okusaka, Takuji|Ishii, Hiroshi|Furuse, Junji | ||||||||||
| PMID: | 29893894 | ||||||||||
| 60. | |||||||||||
| Journal: | Cancer Sci. 2018 Aug 28. | ||||||||||
| Title: | Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ1. | ||||||||||
| Author: | Fujiwara, Hiroaki|Tateishi, Keisuke|Kato, Hiroyuki|Nakatsuka, Takuma|Yamamoto, Keisuke|Tanaka, Yasuo|Ijichi, Hideaki|Takahara, Naminatsu|Mizuno, Suguru|Kogure, Hirofumi|Matsubara, Saburo|Nakai, Yousuke|Koike, Kazuhiko | ||||||||||
| PMID: | 30156013 | ||||||||||
| 61. | |||||||||||
| Journal: | Front Genet. 2018 Aug 15;9:309. | ||||||||||
| Title: | Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type. | ||||||||||
| Author: | Shiao, Meng-Shin|Chiablaem, Khajeelak|Charoensawan, Varodom|Ngamphaiboon, Nuttapong|Jinawath, Natini | ||||||||||
| PMID: | 30158952 | ||||||||||
| 62. | |||||||||||
| Journal: | HPB (Oxford). 2018 Aug 28. pii: S1365-182X(18)32708-4. | ||||||||||
| Title: | Histological and molecular characterization of intrahepatic bile duct cancers suggests an expanded definition of perihilar cholangiocarcinoma. | ||||||||||
| Author: | Akita, Masayuki|Sofue, Keitaro|Fujikura, Kohei|Otani, Kyoko|Itoh, Tomoo|Ajiki, Tetsuo|Fukumoto, Takumi|Zen, Yoh | ||||||||||
| PMID: | 30170977 | ||||||||||
| 63. | |||||||||||
| Journal: | Mod Pathol. 2018 Sep 11. pii: 10.1038/s41379-018-0126-3. | ||||||||||
| Title: | The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma. | ||||||||||
| Author: | Dogan, Snjezana|Frosina, Denise|Fayad, Miriam|de Oliveira, Thais Basili|Alemar, Barbara|Rosenblum, Marc|Tang, Laura H|Hameed, Meera|Xu, Bin|Ghossein, Ronald A|Chute, Deborah J|Weigelt, Britta|Jungbluth, Achim A | ||||||||||
| PMID: | 30206411 | ||||||||||
| 64. | |||||||||||
| Journal: | Cancer Treat Rev. 2018 Sep 8;70:168-177. | ||||||||||
| Title: | Biliary Tract Cancer: State of the Art and potential role of DNA Damage Repair. | ||||||||||
| Author: | Lamarca, Angela|Barriuso, Jorge|McNamara, Mairead G|Valle, Juan W | ||||||||||
| PMID: | 30218788 | ||||||||||
| 65. | |||||||||||
| Journal: | J Surg Res. 2018 Nov;231:116-125. | ||||||||||
| Title: | IDH1 mutation correlates with a beneficial prognosis and suppresses tumor growth in IHCC. | ||||||||||
| Author: | Wang, Jian|Zhang, Zhan-Guo|Ding, Ze-Yang|Dong, Wei|Liang, Hui-Fang|Chu, Liang|Zhang, Bi-Xiang|Chen, Xiao-Ping | ||||||||||
| PMID: | 30278918 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer Sci. 2018 May;109(5):1282-1291. | ||||||||||
| Title: | Molecular genomic landscapes of hepatobiliary cancer. | ||||||||||
| Author: | Shibata, Tatsuhiro|Arai, Yasuhito|Totoki, Yasushi | ||||||||||
| PMID: | 29573058 | ||||||||||
| 67. | |||||||||||
| Journal: | J Hepatol. 2018 Jul;69(1):89-98. | ||||||||||
| Title: | Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Dong, Liang-Qing|Shi, Yang|Ma, Li-Jie|Yang, Liu-Xiao|Wang, Xiao-Ying|Zhang, Shu|Wang, Zhi-Chao|Duan, Meng|Zhang, Zhao|Liu, Long-Zi|Zheng, Bo-Hao|Ding, Zhen-Bin|Ke, Ai-Wu|Gao, Da-Ming|Yuan, Ke|Zhou, Jian|Fan, Jia|Xi, Ruibin|Gao, Qiang | ||||||||||
| PMID: | 29551704 | ||||||||||
| 68. | |||||||||||
| Journal: | Abdom Radiol (NY). 2018 Oct;43(10):2665-2672. | ||||||||||
| Title: | Intrahepatic cholangiocarcinoma: can imaging phenotypes predict survival and tumor genetics? | ||||||||||
| Author: | Aherne, Emily A|Pak, Linda M|Goldman, Debra A|Gonen, Mithat|Jarnagin, William R|Simpson, Amber L|Do, Richard K | ||||||||||
| PMID: | 29492607 | ||||||||||
| 69. | |||||||||||
| Journal: | Expert Opin Emerg Drugs. 2018 Mar;23(1):63-75. | ||||||||||
| Title: | Emerging molecular target antagonists for the treatment of biliary tract cancer. | ||||||||||
| Author: | Lombardi, Pasquale|Marino, Donatella|Fenocchio, Elisabetta|Chila, Giovanna|Aglietta, Massimo|Leone, Francesco | ||||||||||
| PMID: | 29468924 | ||||||||||
| 70. | |||||||||||
| Journal: | Future Oncol. 2018 Mar;14(6):553-566. | ||||||||||
| Title: | Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma. | ||||||||||
| Author: | DeLeon, Thomas T|Ahn, Daniel H|Bogenberger, James M|Anastasiadis, Panos Z|Arora, Mansi|Ramanathan, Ramesh K|Aqel, Bashar A|Vasmatzis, George|Truty, Mark J|Oklu, Rahmi|Bekaii-Saab, Tanios S|Borad, Mitesh J | ||||||||||
| PMID: | 29460642 | ||||||||||
| 71. | |||||||||||
| Journal: | Eur J Cancer. 2018 Mar;92:11-19. | ||||||||||
| Title: | PICCA study: panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer-a randomised biomarker-driven clinical phase II AIO study. | ||||||||||
| Author: | Vogel, Arndt|Kasper, Stefan|Bitzer, Michael|Block, Andreas|Sinn, Marianne|Schulze-Bergkamen, Henning|Moehler, Markus|Pfarr, Nicole|Endris, Volker|Goeppert, Benjamin|Merx, Kirsten|Schnoy, Elisabeth|Siveke, Jens T|Michl, Patrick|Waldschmidt, Dirk|Kuhlmann, | ||||||||||
| PMID: | 29413685 | ||||||||||
| 72. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2360-2368. | ||||||||||
| Title: | Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity. | ||||||||||
| Author: | Liu, Zhen-Hao|Lian, Bao-Feng|Dong, Qiong-Zhu|Sun, Han|Wei, Jin-Wang|Sheng, Yuan-Yuan|Li, Wei|Li, Yi-Xue|Xie, Lu|Liu, Lei|Qin, Lun-Xiu | ||||||||||
| PMID: | 29408647 | ||||||||||
| 73. | |||||||||||
| Journal: | Cancer Control. 2018 Jan-Mar;25(1):1073274817744658. | ||||||||||
| Title: | Primary Liver Cancers, Part 2: Progression Pathways and Carcinogenesis. | ||||||||||
| Author: | Jiang, Kun|Centeno, Barbara A | ||||||||||
| PMID: | 29353494 | ||||||||||
| 74. | |||||||||||
| Journal: | Am J Surg Pathol. 2018 Apr;42(4):512-521. | ||||||||||
| Title: | MDM2 Amplification in Intrahepatic Cholangiocarcinomas: Its Relationship With Large-Duct Type Morphology and Uncommon KRAS Mutations. | ||||||||||
| Author: | Kim, Sung Joo|Akita, Masayuki|Sung, You-Na|Fujikura, Kohei|Lee, Jae Hoon|Hwang, Shin|Yu, Eunsil|Otani, Kyoko|Hong, Seung-Mo|Zen, Yoh | ||||||||||
| PMID: | 29309301 | ||||||||||
| 75. | |||||||||||
| Journal: | Hepatology. 2018 Sep;68(3):949-963. | ||||||||||
| Title: | Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Nepal, Chirag|O'Rourke, Colm J|Oliveira, Douglas V N P|Taranta, Andrzej|Shema, Steven|Gautam, Prson|Calderaro, Julien|Barbour, Andrew|Raggi, Chiara|Wennerberg, Krister|Wang, Xin W|Lautem, Anja|Roberts, Lewis R|Andersen, Jesper B | ||||||||||
| PMID: | 29278425 | ||||||||||
| 76. | |||||||||||
| Journal: | Eur J Cancer. 2018 Feb;90:83-91. | ||||||||||
| Title: | Circulating oncometabolite D-2-hydroxyglutarate enantiomer is a surrogate marker of isocitrate dehydrogenase-mutated intrahepatic cholangiocarcinomas. | ||||||||||
| Author: | Delahousse, Julia|Verlingue, Loic|Broutin, Sophie|Legoupil, Clemence|Touat, Mehdi|Doucet, Ludovic|Ammari, Samy|Lacroix, Ludovic|Ducreux, Michel|Scoazec, Jean-Yves|Malka, David|Paci, Angelo|Hollebecque, Antoine | ||||||||||
| PMID: | 29274619 | ||||||||||
| 77. | |||||||||||
| Journal: | Gastroenterology. 2018 Mar;154(4):1066-1079.e5. | ||||||||||
| Title: | MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma. | ||||||||||
| Author: | Lampis, Andrea|Carotenuto, Pietro|Vlachogiannis, Georgios|Cascione, Luciano|Hedayat, Somaieh|Burke, Rosemary|Clarke, Paul|Bosma, Else|Simbolo, Michele|Scarpa, Aldo|Yu, Sijia|Cole, Rebecca|Smyth, Elizabeth|Mateos, Javier Fernandez|Begum, Ruwaida|Hezelova, | ||||||||||
| PMID: | 29113809 | ||||||||||
| 78. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1454-1460. | ||||||||||
| Title: | Targeting cholangiocarcinoma. | ||||||||||
| Author: | Mertens, Joachim C|Rizvi, Sumera|Gores, Gregory J | ||||||||||
| PMID: | 28844952 | ||||||||||