Primary Site >> Stomach Cancer

Gene >> HPSE

Journal: Anticancer Res. 2001 Sep-Oct;21(5):3365-9.
Title: Heparanase gene expression and metastatic potential in human gastric cancer.
Author: Endo, K|Maejara, U|Baba, H|Tokunaga, E|Koga, T|Ikeda, Y|Toh, Y|Kohnoe, S|Okamura, T|Nakajima, M|Sugimachi, K
PMID: 11848495
Journal: Oncol Rep. 2001 May-Jun;8(3):539-42.
Title: Heparanase expression in clinical digestive malignancies.
Author: Inoue, H|Mimori, K|Utsunomiya, T|Sadanaga, N|Barnard, G F|Ueo, H|Mori, M
PMID: 11295076
Journal: Mod Pathol. 2002 Jun;15(6):593-8.
Title: Heparanase: a key enzyme in invasion and metastasis of gastric carcinoma.
Author: Tang, Weihua|Nakamura, Yasushi|Tsujimoto, Masahiko|Sato, Misako|Wang, Xiaojuan|Kurozumi, Kazushi|Nakahara, Masaaki|Nakao, Kazuyasu|Nakamura, Misa|Mori, Ichiro|Kakudo, Kennichi
PMID: 12065771
Journal: Lab Invest. 2003 May;83(5):613-22.
Title: Heparanase expression correlates with invasion and poor prognosis in gastric cancers.
Author: Takaoka, Munenori|Naomoto, Yoshio|Ohkawa, Takaomi|Uetsuka, Hirokazu|Shirakawa, Yasuhiro|Uno, Futoshi|Fujiwara, Toshiyoshi|Gunduz, Mehmet|Nagatsuka, Hitoshi|Nakajima, Motowo|Tanaka, Noriaki|Haisa, Minoru
PMID: 12746471
Journal: Zhonghua Zhong Liu Za Zhi. 2003 Jul;25(4):368-71.
Title: [Relation of heparanase mRNA expression and angiogenesis to the progression of gastric carcinoma].
Author: Ren, Xiao-long|Zhu, Ren-zhi|Wang, Li-jing|Zhang, Ming-li|Li, Dong-hai|Deng, Xiao-qun
PMID: 12921569
Journal: Zhonghua Yi Xue Za Zhi. 2004 Jun 17;84(12):974-8.
Title: [Increased expression of heparanase mRNA is correlated with metastasis of gastric carcinoma and is probably correlated with c-met protein].
Author: Cai, Yong-guo|Fang, Dian-chun|Yang, Shi-ming|Luo, Yuan-hui|Yang, Meng-hua|Wang, Dong-xu
PMID: 15312528
Journal: Zhonghua Zhong Liu Za Zhi. 2004 Oct;26(10):609-11.
Title: [Relationship between heparanase mRNA expression in human gastric cancer and its clinicopathological features].
Author: Chen, Jun-qiang|Zhan, Wen-hua|He, Yu-long|Peng, Jun-sheng|Wang, Jian-ping|Chen, Zheng-xuan|Huang, Yi-hua|Cai, Shi-rong
PMID: 15634522
Journal: J Surg Oncol. 2005 May 1;90(2):59-65.
Title: Detection of peritoneal micrometastasis by reverse transcriptase-polymerase chain reaction for heparanase mRNA and cytology in peritoneal wash samples.
Author: Wang, Zhenning|Zhang, Xue|Xu, Huimian|Zhou, Xin|Jiang, Li|Lu, Chong
PMID: 15844185
Journal: Mod Pathol. 2005 Feb;18(2):205-11.
Title: Positive association of heparanase expression with tumor invasion and lymphatic metastasis in gastric carcinoma.
Author: Wang, Zhenning|Xu, Huimian|Jiang, Li|Zhou, Xin|Lu, Chong|Zhang, Xue
PMID: 15475937
Journal: Hum Pathol. 2006 Sep;37(9):1145-52.
Title: The close relationship between heparanase and cyclooxygenase-2 expressions in signet-ring cell carcinoma of the stomach.
Author: Ohtawa, Yasuyuki|Naomoto, Yoshio|Shirakawa, Yasuhiro|Takaoka, Munenori|Murata, Toshihiro|Sonoda, Ryotaro|Sakurama, Kazufumi|Yamatsuji, Tomoki|Gunduz, Mehmet|Tsujigiwa, Hidetsugu|Nagatsuka, Hitoshi|Terada, Norihiko|Itano, Satoshi|Horiki, Sadayuki|Yanagihar
PMID: 16938519
Journal: Zhonghua Wai Ke Za Zhi. 2006 Aug 1;44(15):1062-4.
Title: [mRNA expression of syndecan-1 and heparanase in relation to tumor progression and prognosis of gastric carcinoma].
Author: Ru, Guo-qing|Zhao, Zhong-sheng|Tang, Qi-le|Xu, Wen-juan
PMID: 17074248
Journal: Tumour Biol. 2007;28(4):238-46. Epub 2007 Aug 23.
Title: Dendritic cells reconstituted with a human heparanase gene induce potent cytotoxic T-cell responses against gastric tumor cells in vitro.
Author: Cai, Yong-Guo|Fang, Dian-Chun|Chen, Ling|Tang, Xu-Dong|Chen, Ting|Yu, Song-Tao|Luo, Yuan-Hui|Xiong, Zheng|Wang, Dong-Xu|Yang, Shi-Ming
PMID: 17717429
Journal: Asian Pac J Cancer Prev. 2009 Jan-Mar;10(1):151-4.
Title: Role of heparanase-1 in gastric carcinoma invasion.
Author: Yingying, Xu|Yong, Zhang|Zhenning, Wang|Xue, Zhang|Li, Jiang|Yang, Luo|Huimian, Xu
PMID: 19469644
Journal: World J Gastroenterol. 2009 Nov 21;15(43):5442-8.
Title: Stable knockdown of heparanase expression in gastric cancer cells in vitro.
Author: Zheng, Li-Duan|Jiang, Guo-Song|Pu, Jia-Rui|Mei, Hong|Dong, Ji-Hua|Hou, Xiao-Hua|Tong, Qiang-Song
PMID: 19916174
Journal: Pathol Int. 2010 Apr;60(4):268-77.
Title: Abnormal expression of early growth response 1 in gastric cancer: association with tumor invasion, metastasis and heparanase transcription.
Author: Zheng, Liduan|Pu, Jiarui|Jiang, Guosong|Weng, Mixia|He, June|Mei, Hong|Hou, Xiaohua|Tong, Qiangsong
PMID: 20403028
Journal: Zhonghua Zhong Liu Za Zhi. 2010 Sep;32(9):645-9.
Title: [Effect of silencing heparanase on the biological behavior of gastric carcinoma in nude mice].
Author: Huai, Na|Yu, Hong|Ma, Xiu-mei
PMID: 21122375
Journal: APMIS. 2010 Nov;118(11):855-63.
Title: Expression of SATB1 and heparanase in gastric cancer and its relationship to clinicopathologic features.
Author: Cheng, Chao|Lu, Xiaoming|Wang, Guobin|Zheng, Liduan|Shu, Xiaogang|Zhu, Shikai|Liu, Ke|Wu, Ke|Tong, Qiang
PMID: 20955458
Journal: Histopathology. 2010 Jul;57(1):90-100.
Title: Preferential up-regulation of heparanase and cyclooxygenase-2 in carcinogenesis of Barrett's oesophagus and intestinal-type gastric carcinoma.
Author: Sonoda, Ryotaro|Naomoto, Yoshio|Shirakawa, Yasuhiro|Fujiwara, Yasuhiro|Yamatsuji, Tomoki|Noma, Kazuhiro|Tanabe, Shunsuke|Takaoka, Munenori|Gunduz, Mehmet|Tsujigiwa, Hidetsugu|Nagatsuka, Hitoshi|Ohara, Nobuya|Yoshino, Tadashi|Takubo, Kaiyo|Vieth, Michael|T
PMID: 20653782
Journal: J Surg Oncol. 2010 Jul 1;102(1):68-72.
Title: Association of heparanase gene (HPSE-1) single nucleotide polymorphisms with gastric cancer.
Author: Yue, Zhenyu|Song, Yongxi|Wang, Zhenning|Luo, Yang|Jiang, Li|Xing, Lili|Xu, Huimian|Zhang, Xue
PMID: 20578081
Journal: BMC Cancer. 2010 Feb 5;10:33.
Title: Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells.
Author: Zheng, Liduan|Jiang, Guosong|Mei, Hong|Pu, Jiarui|Dong, Jihua|Hou, Xiaohua|Tong, Qiangsong
PMID: 20137078
Journal: PLoS One. 2012;7(1):e30277.
Title: Polymorphisms and a haplotype in heparanase gene associations with the progression and prognosis of gastric cancer in a northern Chinese population.
Author: Li, Ai-Lin|Song, Yong-Xi|Wang, Zhen-Ning|Gao, Peng|Miao, Yuan|Zhu, Jin-Liang|Yue, Zhen-Yu|Xu, Hui-Mian
PMID: 22276173
Journal: PLoS One. 2012;7(2):e31379.
Title: Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells.
Author: Jiang, Guosong|Zheng, Liduan|Pu, Jiarui|Mei, Hong|Zhao, Jun|Huang, Kai|Zeng, Fuqing|Tong, Qiangsong
PMID: 22363633
Journal: Oncol Lett. 2012 Jul;4(1):178-182.
Title: Overexpression of heparanase multiple antigenic peptide 2 is associated with poor prognosis in gastric cancer: Potential for therapy.
Author: Zhang, Jun|Yang, Jianmin|Han, Xiaomei|Zhao, Zhongsheng|DU, Ling|Yu, Tong|Wang, Huiju
PMID: 22807984
Journal: Cancer Lett. 2015 May 28;361(1):57-66.
Title: Hepatocyte growth factor (HGF) upregulates heparanase expression via the PI3K/Akt/NF-kappaB signaling pathway for gastric cancer metastasis.
Author: Hao, Ning-Bo|Tang, Bo|Wang, Guo-Zheng|Xie, Rui|Hu, Chang-Jiang|Wang, Su-Min|Wu, Yu-Yun|Liu, En|Xie, Xia|Yang, Shi-Ming
PMID: 25727320
Journal: Asian Pac J Cancer Prev. 2015;16(18):8653-8.
Title: Heparanase mRNA and Protein Expression Correlates with Clinicopathologic Features of Gastric Cancer Patients: a Meta- analysis.
Author: Li, Hai-Long|Gu, Jing|Wu, Jian-Jun|Ma, Chun-Lin|Yang, Ya-Li|Wang, Hu-Ping|Wang, Jing|Wang, Yong|Chen, Che|Wu, Hong-Yan
PMID: 26745132
Journal: Thromb Res. 2016 Apr;140 Suppl 1:S184-5.
Title: PO-23 - Expression of heparanase in cancer as biomarker of malignancies: overexpression in an aggressive, poor survival gastric cancer "gastric signet ring cell carcinoma" compared with that of other gastric cancers.
Author: Fourgeaud, C|Derieux, S|Mirshahi, S|Besbes, S|Chidiac, J|Mahe, I|Contant, G|Pocard, M|Soria, J|Mirshahi, M
PMID: 27161709
Journal: Cell Death Dis. 2016 Sep 29;7(9):e2382.
Title: miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression.
Author: Zheng, Liduan|Jiao, Wanju|Song, Huajie|Qu, Hongxia|Li, Dan|Mei, Hong|Chen, Yajun|Yang, Feng|Li, Huanhuan|Huang, Kai|Tong, Qiangsong
PMID: 27685626
Journal: Oncol Lett. 2017 May;13(5):3739-3745.
Title: MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer.
Author: Shi, Jinxin|Chen, Ping|Sun, Jingxu|Song, Yongxi|Ma, Bin|Gao, Peng|Chen, Xiaowan|Wang, Zhenning
PMID: 28521475
Journal: Exp Ther Med. 2018 Feb;15(2):1927-1933.
Title: MicroRNA-429 decreases the invasion ability of gastric cancer cell line BGC-823 by downregulating the expression of heparanase.
Author: Sheng, Nan|Zhang, Lin|Yang, Shaofeng
PMID: 29434786
Journal: Mol Med Rep. 2018 Oct 15.
Title: Helicobacter pylori infection enhances heparanase leading to cell proliferation via mitogenactivated protein kinase signalling in human gastric cancer cells.
Author: Liu, Liping|Zhao, Yongxun|Fan, Guangrui|Shuai, Tiankui|Li, Bin|Li, Yumin
PMID: 30320396
Journal: World J Gastroenterol. 2018 Oct 28;24(40):4565-4577.
Title: Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression.
Author: Liu, Li-Ping|Sheng, Xi-Ping|Shuai, Tian-Kui|Zhao, Yong-Xun|Li, Bin|Li, Yu-Min
PMID: 30386106