Primary Site >> Pancreatic Cancer
Gene >> HDAC9
| 1. | |||||||||||
| Journal: | Int J Cancer. 2007 Aug 1;121(3):656-65. | ||||||||||
| Title: | Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. | ||||||||||
| Author: | Kumagai, Takashi|Wakimoto, Naoki|Yin, Dong|Gery, Sigal|Kawamata, Norihiko|Takai, Noriyuki|Komatsu, Naoki|Chumakov, Alexy|Imai, Yasufumi|Koeffler, H Phillip | ||||||||||
| PMID: | 17417771 | ||||||||||
| 2. | |||||||||||
| Journal: | ChemMedChem. 2008 Mar;3(3):487-501. | ||||||||||
| Title: | Chemistry, biology, and QSAR studies of substituted biaryl hydroxamates and mercaptoacetamides as HDAC inhibitors-nanomolar-potency inhibitors of pancreatic cancer cell growth. | ||||||||||
| Author: | Kozikowski, Alan P|Chen, Yufeng|Gaysin, Arsen M|Savoy, Doris N|Billadeau, Daniel D|Kim, Ki Hwan | ||||||||||
| PMID: | 18181121 | ||||||||||
| 3. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2008 Apr 15;18(8):2549-54. | ||||||||||
| Title: | Synthesis and biological evaluation of histone deacetylase inhibitors that are based on FR235222: a cyclic tetrapeptide scaffold. | ||||||||||
| Author: | Singh, Erinprit K|Ravula, Suchitra|Pan, Chung-Mao|Pan, Po-Shen|Vasko, Robert C|Lapera, Stephanie A|Weerasinghe, Sujith V W|Pflum, Mary Kay H|McAlpine, Shelli R | ||||||||||
| PMID: | 18381239 | ||||||||||
| 4. | |||||||||||
| Journal: | Curr Genomics. 2008 Mar;9(1):22-4. | ||||||||||
| Title: | Array-based approaches for the identification of epigenetic silenced tumor suppressor genes. | ||||||||||
| Author: | Takai, Noriyuki|Narahara, Hisashi | ||||||||||
| PMID: | 19424480 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cancer Ther. 2010 Jun;9(6):1596-608. | ||||||||||
| Title: | Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells. | ||||||||||
| Author: | Batra, Sanjay|Sahu, Ravi P|Kandala, Prabodh K|Srivastava, Sanjay K | ||||||||||
| PMID: | 20484017 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Clin Oncol. 2011 Dec;16(6):671-8. | ||||||||||
| Title: | Histone deacetylase inhibitor augments anti-tumor effect of gemcitabine and pegylated interferon-alpha on pancreatic cancer cells. | ||||||||||
| Author: | Iwahashi, Shuichi|Shimada, Mitsuo|Utsunomiya, Tohru|Morine, Yuji|Imura, Satoru|Ikemoto, Tetsuya|Mori, Hiroki|Hanaoka, Jun|Sugimoto, Koji|Saito, Yu | ||||||||||
| PMID: | 21556798 | ||||||||||
| 7. | |||||||||||
| Journal: | Drug Discov Ther. 2011 Dec;5(6):266-78. | ||||||||||
| Title: | Effective neurofibromatosis therapeutics blocking the oncogenic kinase PAK1. | ||||||||||
| Author: | Maruta, H | ||||||||||
| PMID: | 22466437 | ||||||||||
| 8. | |||||||||||
| Journal: | Gut. 2012 Mar;61(3):439-48. | ||||||||||
| Title: | Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer. | ||||||||||
| Author: | Aghdassi, Ali|Sendler, Matthias|Guenther, Annett|Mayerle, Julia|Behn, Claas-Olsen|Heidecke, Claus-Dieter|Friess, Helmut|Buchler, Markus|Evert, Matthias|Lerch, Markus M|Weiss, Frank Ulrich | ||||||||||
| PMID: | 22147512 | ||||||||||
| 9. | |||||||||||
| Journal: | Gut. 2012 Mar;61(3):329-30. | ||||||||||
| Title: | A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer. | ||||||||||
| Author: | Schneider, Gunter|Kramer, Oliver H|Saur, Dieter | ||||||||||
| PMID: | 22147511 | ||||||||||
| 10. | |||||||||||
| Journal: | Invest New Drugs. 2012 Dec;30(6):2303-17. | ||||||||||
| Title: | Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination. | ||||||||||
| Author: | Millward, Michael|Price, Timothy|Townsend, Amanda|Sweeney, Christopher|Spencer, Andrew|Sukumaran, Shawgi|Longenecker, Angie|Lee, Lonnie|Lay, Ana|Sharma, Girish|Gemmill, Robert M|Drabkin, Harry A|Lloyd, G Kenneth|Neuteboom, Saskia T C|McConkey, David J|Pal | ||||||||||
| PMID: | 22080430 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Oncol. 2013 Jan;42(1):349-58. | ||||||||||
| Title: | (-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity. | ||||||||||
| Author: | Kim, Sung Ok|Kim, Mi Ryeo | ||||||||||
| PMID: | 23135610 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncotarget. 2015 Apr 10;6(10):7504-21. | ||||||||||
| Title: | TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis. | ||||||||||
| Author: | Gore, Jesse|Craven, Kelly E|Wilson, Julie L|Cote, Gregory A|Cheng, Monica|Nguyen, Hai V|Cramer, Harvey M|Sherman, Stuart|Korc, Murray | ||||||||||
| PMID: | 25762644 | ||||||||||
| 13. | |||||||||||
| Journal: | Tumour Biol. 2015 Nov;36(11):9015-22. | ||||||||||
| Title: | Targeting pancreatic cancer cells by a novel hydroxamate-based histone deacetylase (HDAC) inhibitor ST-3595. | ||||||||||
| Author: | Minjie, Shang|Defei, Hong|Zhimin, Hu|Weiding, Wu|Yuhua, Zhang | ||||||||||
| PMID: | 26084607 | ||||||||||
| 14. | |||||||||||
| Journal: | Biomed Pharmacother. 2015 Aug;74:257-64. | ||||||||||
| Title: | Combination of HDAC inhibitor TSA and silibinin induces cell cycle arrest and apoptosis by targeting survivin and cyclinB1/Cdk1 in pancreatic cancer cells. | ||||||||||
| Author: | Feng, Wan|Cai, Dawei|Zhang, Bin|Lou, Guochun|Zou, Xiaoping | ||||||||||
| PMID: | 26349994 | ||||||||||
| 15. | |||||||||||
| Journal: | Tumour Biol. 2016 Apr;37(4):4323-30. | ||||||||||
| Title: | SAHA, an HDAC inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by modulating E-cadherin. | ||||||||||
| Author: | Park, Seong Joon|Kim, Seung-Mi|Moon, Jai-Hee|Kim, Jeong Hee|Shin, Jae-Sik|Hong, Seung-Woo|Shin, Yu Jin|Lee, Dae-Hee|Lee, Eun Young|Hwang, Ih-Yeon|Kim, Jeong Eun|Kim, Kyu-Pyo|Hong, Yong Sang|Lee, Won-Keun|Choi, Eun Kyung|Lee, Jung Shin|Jin, Dong-Hoon|Kim, | ||||||||||
| PMID: | 26493999 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncotarget. 2016 Jan 5;7(1):323-41. | ||||||||||
| Title: | Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes. | ||||||||||
| Author: | Craven, Kelly E|Gore, Jesse|Wilson, Julie L|Korc, Murray | ||||||||||
| PMID: | 26586478 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91. | ||||||||||
| Title: | Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study. | ||||||||||
| Author: | Childs, Erica J|Chaffee, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Cote, Michele L|Bondy, Melissa L|Hruban, Ralph H|Chanock, Stephen J|Hoover, Robert N|Fuchs, Charles S|Rider, David N|Amundadottir, Laufey T|Stolzenberg-Solomon, Rachael|Wolpin | ||||||||||
| PMID: | 27197284 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncotarget. 2017 Feb 28;8(9):14748-14758. | ||||||||||
| Title: | A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis. | ||||||||||
| Author: | Zhu, Bing-Yan|Shang, Bo-Yang|Du, Yue|Li, Yi|Li, Liang|Xu, Xian-Dong|Zhen, Yong-Su | ||||||||||
| PMID: | 28107195 | ||||||||||
| 19. | |||||||||||
| Journal: | Invest New Drugs. 2018 Jul 11. pii: 10.1007/s10637-018-0634-5. | ||||||||||
| Title: | Phase I study of resminostat, an HDAC inhibitor, combined with S-1 in patients with pre-treated biliary tract or pancreatic cancer. | ||||||||||
| Author: | Ikeda, Masafumi|Ohno, Izumi|Ueno, Hideki|Mitsunaga, Shuichi|Hashimoto, Yusuke|Okusaka, Takuji|Kondo, Shunsuke|Sasaki, Mitsuhito|Sakamoto, Yasunari|Takahashi, Hideaki|Hara, Rina|Kobayashi, Shingo|Nakamura, Osamu|Morizane, Chigusa | ||||||||||
| PMID: | 29995287 | ||||||||||