Primary Site >> Liver Cancer

Gene >> GPC3

Journal:
Title: Simpson-Golabi-Behmel Syndrome Type 1
Author: Golabi, Mahin|Leung, Alva|Lopez, Christina
PMID: 20301398
Journal: Cancer Res. 1997 Nov 15;57(22):5179-84.
Title: Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: biological significance and temporospatial distribution.
Author: Hsu, H C|Cheng, W|Lai, P L
PMID: 9371521
Journal: J Med Genet. 1998 Feb;35(2):153-6.
Title: A patient with Simpson-Golabi-Behmel syndrome and hepatocellular carcinoma.
Author: Lapunzina, P|Badia, I|Galoppo, C|De Matteo, E|Silberman, P|Tello, A|Grichener, J|Hughes-Benzie, R
PMID: 9507397
Journal: Zhonghua Wai Ke Za Zhi. 1999 Mar;37(3):171-3, 10.
Title: [Expression and significance of MXR7 mRNA in human hepatocellular carcinoma].
Author: Zhou, X|Wang, H|Yang, G|Chen, Z|Li, B|Wu, M
PMID: 11829813
Journal: World J Gastroenterol. 2000 Feb;6(1):57-60.
Title: Cloning and expression of MXR7 gene in human HCC tissue.
Author: Zhou, Xue-Ping|Wang, Hong-Yang|Yang, Guang-Shun|Chen, Zheng-Jun|Li, Bao-An|Wu, Meng-Chao
PMID: 11819523
Journal: Int J Cancer. 2003 Feb 10;103(4):455-65.
Title: Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.
Author: Midorikawa, Yutaka|Ishikawa, Shumpei|Iwanari, Hiroko|Imamura, Takeshi|Sakamoto, Hirohiko|Miyazono, Kohei|Kodama, Tatsuhiko|Makuuchi, Masatoshi|Aburatani, Hiroyuki
PMID: 12478660
Journal: Cancer Sci. 2003 Mar;94(3):259-62.
Title: Glypican-3 is overexpressed in human hepatocellular carcinoma.
Author: Sung, Young Kwan|Hwang, Sun Young|Park, Mi Kyung|Farooq, Mohammad|Han, In Sook|Bae, Han Ik|Kim, Jung-Chul|Kim, Moonkyu
PMID: 12824919
Journal: Gastroenterology. 2003 Jul;125(1):89-97.
Title: Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma.
Author: Capurro, Mariana|Wanless, Ian R|Sherman, Morris|Deboer, Gerrit|Shi, Wen|Miyoshi, Eiji|Filmus, Jorge
PMID: 12851874
Journal: Exp Mol Med. 2003 Aug 31;35(4):257-62.
Title: Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling.
Author: Sung, Young Kwan|Hwang, Sung Young|Farooq, Mohammad|Kim, Jung-Chul|Kim, Moon Kyu
PMID: 14508064
Journal: Biochem Biophys Res Commun. 2004 Mar 19;315(4):950-8.
Title: Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma.
Author: Huang, Jhy-Shrian|Chao, Chuan-Chuan|Su, Teh-Li|Yeh, Shiou-Hwei|Chen, Ding-Shinn|Chen, Chiung-Tong|Chen, Pei-Jer|Jou, Yuh-Shan
PMID: 14985104
Journal: Cancer Res. 2004 Apr 1;64(7):2418-23.
Title: Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma.
Author: Hippo, Yoshitaka|Watanabe, Kiyotaka|Watanabe, Akira|Midorikawa, Yutaka|Yamamoto, Shogo|Ihara, Sigeo|Tokita, Susumu|Iwanari, Hiroko|Ito, Yukio|Nakano, Kiyotaka|Nezu, Jun-ichi|Tsunoda, Hiroyuki|Yoshino, Takeshi|Ohizumi, Iwao|Tsuchiya, Masayuki|Ohnishi, Shin
PMID: 15059894
Journal: Clin Cancer Res. 2004 Oct 1;10(19):6612-21.
Title: Identification of glypican-3 as a novel tumor marker for melanoma.
Author: Nakatsura, Tetsuya|Kageshita, Toshiro|Ito, Shosuke|Wakamatsu, Kazumasa|Monji, Mikio|Ikuta, Yoshiaki|Senju, Satoru|Ono, Tomomichi|Nishimura, Yasuharu
PMID: 15475451
Journal: Clin Cancer Res. 2004 Dec 15;10(24):8630-40.
Title: Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice.
Author: Nakatsura, Tetsuya|Komori, Hiroyuki|Kubo, Tatsuko|Yoshitake, Yoshihiro|Senju, Satoru|Katagiri, Toyomasa|Furukawa, Yoichi|Ogawa, Michio|Nakamura, Yusuke|Nishimura, Yasuharu
PMID: 15623647
Journal: Mol Diagn. 2004;8(4):207-12.
Title: Glypican-3 and alphafetoprotein as diagnostic tests for hepatocellular carcinoma.
Author: Filmus, Jorge|Capurro, Mariana
PMID: 15887976
Journal: Oncogene. 2005 May 26;24(23):3737-47.
Title: An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma.
Author: Patil, Mohini A|Chua, Mei-Sze|Pan, Kuang-Hung|Lin, Richard|Lih, Chih-Jian|Cheung, Siu-Tim|Ho, Coral|Li, Rui|Fan, Sheung-Tat|Cohen, Stanley N|Chen, Xin|So, Samuel
PMID: 15735714
Journal: BMC Bioinformatics. 2005 Apr 13;6:97.
Title: Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery.
Author: Grate, Leslie R
PMID: 15826317
Journal: J Gastroenterol. 2005 Mar;40 Suppl 16:1-6.
Title: Discovery of a new biomarker for gastroenterological cancers.
Author: Aburatani, Hiroyuki
PMID: 15902956
Journal: Mod Pathol. 2005 Dec;18(12):1591-8.
Title: The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.
Author: Yamauchi, Naoko|Watanabe, Akira|Hishinuma, Michiyo|Ohashi, Ken-Ichi|Midorikawa, Yutaka|Morishita, Yasuyuki|Niki, Toshiro|Shibahara, Junji|Mori, Masaya|Makuuchi, Masatoshi|Hippo, Yoshitaka|Kodama, Tatsuhiko|Iwanari, Hiroko|Aburatani, Hiroyuki|Fukayama, Mas
PMID: 15920546
Journal: World J Gastroenterol. 2005 Jul 7;11(25):3850-4.
Title: Expression and significance of tumor-related genes in HCC.
Author: Lu, Zi-Li|Luo, Dian-Zhong|Wen, Jian-Ming
PMID: 15991281
Journal: Cancer Res. 2005 Jul 15;65(14):6245-54.
Title: Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling.
Author: Capurro, Mariana I|Xiang, Yun-Yan|Lobe, Corrinne|Filmus, Jorge
PMID: 16024626
Journal: Liver Int. 2005 Oct;25(5):962-6.
Title: Upregulation of Glypican-3 expression in hepatocellular carcinoma but downregulation in cholangiocarcinoma indicates its differential diagnosis value in primary liver cancers.
Author: Man, Xiao-Bo|Tang, Liang|Zhang, Bao-Hua|Li, Shen-Jing|Qiu, Xiu-Hua|Wu, Meng-Chao|Wang, Hong-Yang
PMID: 16162153
Journal: J Biol Chem. 2005 Dec 16;280(50):41201-6.
Title: Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth.
Author: Capurro, Mariana I|Shi, Wen|Sandal, Shaifali|Filmus, Jorge
PMID: 16227623
Journal: Clin Biochem Rev. 2005 Aug;26(3):65-79.
Title: Recent developments in the first detection of hepatocellular carcinoma.
Author: Lopez, Joseph B
PMID: 16450014
Journal: Cancer Res. 2006 Feb 15;66(4):2414-22.
Title: Embryonic stem cell-derived dendritic cells expressing glypican-3, a recently identified oncofetal antigen, induce protective immunity against highly metastatic mouse melanoma, B16-F10.
Author: Motomura, Yutaka|Senju, Satoru|Nakatsura, Tetsuya|Matsuyoshi, Hidetake|Hirata, Shinya|Monji, Mikio|Komori, Hiroyuki|Fukuma, Daiki|Baba, Hideo|Nishimura, Yasuharu
PMID: 16489048
Journal: Clin Cancer Res. 2006 May 1;12(9):2689-97.
Title: Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma.
Author: Komori, Hiroyuki|Nakatsura, Tetsuya|Senju, Satoru|Yoshitake, Yoshihiro|Motomura, Yutaka|Ikuta, Yoshiaki|Fukuma, Daiki|Yokomine, Kazunori|Harao, Michiko|Beppu, Toru|Matsui, Masanori|Torigoe, Toshihiko|Sato, Noriyuki|Baba, Hideo|Nishimura, Yasuharu
PMID: 16675560
Journal: Mol Cells. 2006 Apr 30;21(2):224-8.
Title: Cellular changes resulting from forced expression of glypican-3 in hepatocellular carcinoma cells.
Author: Kwack, Mi Hee|Choi, Byung Yeol|Sung, Young Kwan
PMID: 16682817
Journal: Hepatobiliary Pancreat Dis Int. 2006 May;5(2):257-61.
Title: Gradual upregulation of OCI-5 expression during occurrence and progression of rat hepatocellular carcinoma.
Author: Jiang, Wei-Jun|Man, Xiao-Bo|Tang, Liang|Song, Hong-Yin|Li, Shen-Jing|Cai, Guo-Jun|Qiu, Xiu-Hua|Hu, He-Ping
PMID: 16698587
Journal: Zhonghua Wai Ke Za Zhi. 2006 Apr 1;44(7):458-62.
Title: [Significance of glypican-3 mRNA expression in hepatocellular carcinoma tissues and peripheral blood cells].
Author: Li, Bao-ding|Zhao, Qing-chuan|Zhu, Yang-ting|Zhang, Fu-qin|Dou, Ke-feng
PMID: 16772080
Journal: Am J Surg Pathol. 2006 Nov;30(11):1405-11.
Title: Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules.
Author: Libbrecht, Louis|Severi, Tamara|Cassiman, David|Vander Borght, Sara|Pirenne, Jacques|Nevens, Frederik|Verslype, Chris|van Pelt, Jos|Roskams, Tania
PMID: 17063081
Journal: Gastroenterology. 2006 Dec;131(6):1758-67.
Title: A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
Author: Llovet, Josep M|Chen, Yingbei|Wurmbach, Elisa|Roayaie, Sasan|Fiel, M Isabel|Schwartz, Myron|Thung, Swan N|Khitrov, Gregory|Zhang, Weijia|Villanueva, Augusto|Battiston, Carlo|Mazzaferro, Vincenzo|Bruix, Jordi|Waxman, Samuel|Friedman, Scott L
PMID: 17087938
Journal: Lab Invest. 2006 Dec;86(12):1272-84.
Title: The oncofetal protein glypican-3 is a novel marker of hepatic progenitor/oval cells.
Author: Grozdanov, Petar N|Yovchev, Mladen I|Dabeva, Mariana D
PMID: 17117158
Journal: Gan To Kagaku Ryoho. 2006 Nov;33(12):1742-4.
Title: [Possibilities of glypican-3-specific immunotherapy for hepatocellular carcinoma].
Author: Komori, Hiroyuki|Nakatsura, Tetsuya|Beppu, Toru|Nishimura, Yasuharu|Baba, Hideo
PMID: 17212093
Journal: Clin Cancer Res. 2007 Feb 15;13(4):1133-9.
Title: Gene expression profiling reveals potential biomarkers of human hepatocellular carcinoma.
Author: Jia, Hu-Liang|Ye, Qing-Hai|Qin, Lun-Xiu|Budhu, Anuradha|Forgues, Marshonna|Chen, Yidong|Liu, Yin-Kun|Sun, Hui-Chuan|Wang, Lu|Lu, Hong-Zhou|Shen, Fang|Tang, Zhao-You|Wang, Xin Wei
PMID: 17317821
Journal: Hepatology. 2007 Nov;46(5):1541-7.
Title: The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2.
Author: Morford, Lorri A|Davis, Christina|Jin, Lin|Dobierzewska, Aneta|Peterson, Martha L|Spear, Brett T
PMID: 17668883
Journal: Cancer. 2007 Oct 25;111(5):316-22.
Title: Glypican-3 immunocytochemistry in liver fine-needle aspirates : a novel stain to assist in the differentiation of benign and malignant liver lesions.
Author: Kandil, Dina|Leiman, Gladwyn|Allegretta, Mark|Trotman, Winifred|Pantanowitz, Liron|Goulart, Robert|Evans, Mark
PMID: 17763368
Journal: Mod Pathol. 2008 May;21(5):626-31.
Title: Utility of glypican-3 in differentiating hepatocellular carcinoma from other primary and metastatic lesions in FNA of the liver: an immunocytochemical study.
Author: Ligato, Saverio|Mandich, Daniza|Cartun, Richard W
PMID: 18264086
Journal: Am J Surg Pathol. 2008 Mar;32(3):433-44.
Title: Distinction of hepatocellular carcinoma from benign hepatic mimickers using Glypican-3 and CD34 immunohistochemistry.
Author: Coston, Wanda M P|Loera, Sofia|Lau, Sean K|Ishizawa, Shin|Jiang, Zhong|Wu, Chin-Lee|Yen, Yun|Weiss, Lawrence M|Chu, Peiguo G
PMID: 18300806
Journal: Hepatology. 2008 Apr;47(4):1211-22.
Title: Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
Author: Lai, Jin-Ping|Sandhu, Dalbir S|Yu, Chunrong|Han, Tao|Moser, Catherine D|Jackson, Kenard K|Guerrero, Ruben Bonilla|Aderca, Ileana|Isomoto, Hajime|Garrity-Park, Megan M|Zou, Hongzhi|Shire, Abdirashid M|Nagorney, David M|Sanderson, Schuyler O|Adjei, Alex A|L
PMID: 18318435
Journal: Eur J Cancer. 2008 Apr;44(6):885-97.
Title: Molecular mapping of human hepatocellular carcinoma provides deeper biological insight from genomic data.
Author: Kittaka, Nobuyoshi|Takemasa, Ichiro|Takeda, Yutaka|Marubashi, Shigeru|Nagano, Hiroaki|Umeshita, Koji|Dono, Keizo|Matsubara, Kenichi|Matsuura, Nariaki|Monden, Morito
PMID: 18337085
Journal: Carcinogenesis. 2008 Jul;29(7):1319-26.
Title: Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway.
Author: Cheng, Wei|Tseng, Chia-Jen|Lin, Tom T C|Cheng, I|Pan, Hung-Wei|Hsu, Hey-Chi|Lee, Yu-May
PMID: 18413366
Journal: Int J Oncol. 2008 May;32(5):985-90.
Title: HLA-A2 and -A24-restricted glypican-3-derived peptide vaccine induces specific CTLs: preclinical study using mice.
Author: Motomura, Yutaka|Ikuta, Yoshiaki|Kuronuma, Toshimitsu|Komori, Hiroyuki|Ito, Masaaki|Tsuchihara, Masami|Tsunoda, Yoshiyuki|Shirakawa, Hirofumi|Baba, Hideo|Nishimura, Yasuharu|Kinoshita, Taira|Nakatsura, Tetsuya
PMID: 18425324
Journal: Am J Clin Pathol. 2008 Jun;129(6):899-906.
Title: Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples.
Author: Baumhoer, Daniel|Tornillo, Luigi|Stadlmann, Sylvia|Roncalli, Massimo|Diamantis, Eva Karamitopoulou|Terracciano, Luigi M
PMID: 18480006
Journal: Am J Clin Pathol. 2008 Aug;130(2):219-23.
Title: Value of glypican 3 immunostaining in the diagnosis of hepatocellular carcinoma on needle biopsy.
Author: Anatelli, Florencia|Chuang, Shang-Tian|Yang, Ximing J|Wang, Hanlin L
PMID: 18628090
Journal: Pol J Pathol. 2008;59(1):15-20.
Title: Glypican-3 is expressed in chromophobe renal cell carcinomas.
Author: Okon, Krzysztof
PMID: 18655366
Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2008 Oct;31(5):383-91.
Title: [Usefulness of a novel oncofetal antigen, glypican-3, for diagnosis and immunotherapy of hepatocellular carcinoma].
Author: Nishimura, Yasuharu|Nakatsura, Tetsuya|Senju, Satoru
PMID: 18974622
Journal: Arch Pathol Lab Med. 2008 Nov;132(11):1723-8.
Title: Glypican-3 as a useful diagnostic marker that distinguishes hepatocellular carcinoma from benign hepatocellular mass lesions.
Author: Wang, Hanlin L|Anatelli, Florencia|Zhai, Qihui Jim|Adley, Brian|Chuang, Shang-Tian|Yang, Ximing J
PMID: 18976006
Journal: Cancer Res. 2008 Dec 1;68(23):9832-8.
Title: Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer.
Author: Ishiguro, Takahiro|Sugimoto, Masamichi|Kinoshita, Yasuko|Miyazaki, Yoko|Nakano, Kiyotaka|Tsunoda, Hiroyuki|Sugo, Izumi|Ohizumi, Iwao|Aburatani, Hiroyuki|Hamakubo, Takao|Kodama, Tatsuhiko|Tsuchiya, Masayuki|Yamada-Okabe, Hisafumi
PMID: 19047163
Journal: Biochem Biophys Res Commun. 2009 Jan 9;378(2):279-84.
Title: Anti-glypican 3 antibodies cause ADCC against human hepatocellular carcinoma cells.
Author: Nakano, Kiyotaka|Orita, Tetsuro|Nezu, Junichi|Yoshino, Takeshi|Ohizumi, Iwao|Sugimoto, Masamichi|Furugaki, Koh|Kinoshita, Yasuko|Ishiguro, Takahiro|Hamakubo, Takao|Kodama, Tatsuhiko|Aburatani, Hiroyuki|Yamada-Okabe, Hisafumi|Tsuchiya, Masayuki
PMID: 19022220
Journal: Liver Int. 2009 Aug;29(7):1056-64.
Title: The expression profile of glypican-3 and its relation to macrophage population in human hepatocellular carcinoma.
Author: Takai, Hirotake|Kato, Atsuhiko|Kato, Chie|Watanabe, Takeshi|Matsubara, Koichi|Suzuki, Masami|Kataoka, Hiroaki
PMID: 19141032
Journal: Int J Oncol. 2009 Mar;34(3):649-56.
Title: Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer.
Author: Shirakawa, Hirofumi|Kuronuma, Toshimitsu|Nishimura, Yoshiko|Hasebe, Takahiro|Nakano, Masayuki|Gotohda, Naoto|Takahashi, Shinichiro|Nakagohri, Toshio|Konishi, Masaru|Kobayashi, Nobuaki|Kinoshita, Taira|Nakatsura, Tetsuya
PMID: 19212669
Journal: J Hepatol. 2009 Apr;50(4):746-54.
Title: The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma.
Author: Di Tommaso, Luca|Destro, Annarita|Seok, Jae Yeon|Balladore, Emanuela|Terracciano, Luigi|Sangiovanni, Angelo|Iavarone, Massimo|Colombo, Massimo|Jang, Ja June|Yu, Eunsil|Jin, So Young|Morenghi, Emanuela|Park, Young Nyun|Roncalli, Massimo
PMID: 19231003
Journal: Cancer Sci. 2009 Apr;100(4):626-32.
Title: Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas.
Author: Ushiku, Tetsuo|Uozaki, Hiroshi|Shinozaki, Aya|Ota, Satoshi|Matsuzaka, Keisuke|Nomura, Sachiyo|Kaminishi, Michio|Aburatani, Hiroyuki|Kodama, Tatsuhiko|Fukayama, Masashi
PMID: 19243386
Journal: Cancer Biol Ther. 2009 May;8(10):930-8. Epub 2009 May 10.
Title: Histopathological analyses of the antitumor activity of anti-glypican-3 antibody (GC33) in human liver cancer xenograft models: The contribution of macrophages.
Author: Takai, Hirotake|Kato, Atsuhiko|Kinoshita, Yasuko|Ishiguro, Takahiro|Takai, Yayoi|Ohtani, Yoshimi|Sugimoto, Masamichi|Suzuki, Masami
PMID: 19276671
Journal: Cancer Sci. 2009 Aug;100(8):1403-7.
Title: Glypican-3 expression is correlated with poor prognosis in hepatocellular carcinoma.
Author: Shirakawa, Hirofumi|Suzuki, Hitomi|Shimomura, Manami|Kojima, Motohiro|Gotohda, Naoto|Takahashi, Shinichiro|Nakagohri, Toshio|Konishi, Masaru|Kobayashi, Nobuaki|Kinoshita, Taira|Nakatsura, Tetsuya
PMID: 19496787
Journal: Oncol Rep. 2009 Jul;22(1):149-54.
Title: Detection of glypican-3-specific CTLs in chronic hepatitis and liver cirrhosis.
Author: Hayashi, Emiko|Motomura, Yutaka|Shirakawa, Hirofumi|Yoshikawa, Toshiaki|Oba, Nobuyuki|Nishinakagawa, Shuta|Mizuguchi, Yasuhiro|Kojima, Tatsuya|Nomura, Kazuhiro|Nakatsura, Tetsuya
PMID: 19513517
Journal: Cancer. 2009 Aug 25;117(4):271-8.
Title: Glypican-3 protein expression in primary and metastatic melanoma: a combined immunohistochemistry and immunocytochemistry study.
Author: Kandil, Dina|Leiman, Gladwyn|Allegretta, Mark|Evans, Mark
PMID: 19517479
Journal: Adv Anat Pathol. 2009 Mar;16(2):125-9.
Title: Glypican-3: a novel diagnostic marker for hepatocellular carcinoma and more.
Author: Kandil, Dina H|Cooper, Kumarasen
PMID: 19550373
Journal: Am J Pathol. 2009 Aug;175(2):717-24.
Title: Investigation of the role of glypican 3 in liver regeneration and hepatocyte proliferation.
Author: Liu, Bowen|Paranjpe, Shirish|Bowen, William C|Bell, Aaron W|Luo, Jian-Hua|Yu, Yan-Ping|Mars, Wendy M|Michalopoulos, George K
PMID: 19574424
Journal: Cancer Biol Ther. 2009 Dec;8(24):2329-38. Epub 2009 Dec 3.
Title: Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma.
Author: Takai, Hirotake|Ashihara, Motohki|Ishiguro, Takahiro|Terashima, Hiromichi|Watanabe, Takeshi|Kato, Atsuhiko|Suzuki, Masami
PMID: 19838081
Journal: Acta Histochem. 2010 May;112(3):240-50.
Title: Optimization of tissue processing for immunohistochemistry for the detection of human glypican-3.
Author: Takai, Hirotake|Kato, Atsuhiko|Ishiguro, Takahiro|Kinoshita, Yasuko|Karasawa, Yayoi|Otani, Yoshimi|Sugimoto, Masamichi|Suzuki, Masami|Kataoka, Hiroaki
PMID: 19246079
Journal: J Gastroenterol Hepatol. 2010 Jan;25(1):129-37.
Title: Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers.
Author: Tangkijvanich, Pisit|Chanmee, Theerawut|Komtong, Sanpoj|Mahachai, Varocha|Wisedopas, Naruemon|Pothacharoen, Peraphan|Kongtawelert, Prachya
PMID: 19793164
Journal: Int J Cancer. 2010 Mar 15;126(6):1291-301.
Title: Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo.
Author: Zittermann, Sandra I|Capurro, Mariana I|Shi, Wen|Filmus, Jorge
PMID: 19816934
Journal: Am J Surg Pathol. 2010 Apr;34(4):533-40.
Title: SALL4 represents fetal gut differentiation of gastric cancer, and is diagnostically useful in distinguishing hepatoid gastric carcinoma from hepatocellular carcinoma.
Author: Ushiku, Tetsuo|Shinozaki, Aya|Shibahara, Junji|Iwasaki, Yoshiaki|Tateishi, Yoko|Funata, Nobuaki|Fukayama, Masashi
PMID: 20182341
Journal: Oncol Rep. 2010 May;23(5):1325-30.
Title: Identification of beta2-microgloblin as a candidate for early diagnosis of imaging-invisible hepatocellular carcinoma in patient with liver cirrhosis.
Author: Saito, Yumi|Oba, Nobuyuki|Nishinakagawa, Syuta|Mizuguchi, Yasuhiro|Kojima, Tatsuya|Nomura, Kazuhiro|Nakatsura, Tetsuya
PMID: 20372847
Journal: Hepatol Res. 2010 May;40(5):477-85.
Title: Evaluation for clinical utility of GPC3, measured by a commercially available ELISA kit with Glypican-3 (GPC3) antibody, as a serological and histological marker for hepatocellular carcinoma.
Author: Yasuda, Eisuke|Kumada, Takashi|Toyoda, Hidenori|Kaneoka, Yuji|Maeda, Atsuyuki|Okuda, Seiji|Yoshimi, Naoki|Kozawa, Osamu
PMID: 20374302
Journal: Clin Biochem. 2010 Aug;43(12):1003-8.
Title: Development of a competitive radioimmunoassay for glypican-3 and the clinical application in diagnosis of hepatocellular carcinoma.
Author: Zhang, Qianyun|Xiao, Qin|Lin, Zhen|Ying, Xitang|Li, Zhenjia|Lin, Jin-Ming
PMID: 20444424
Journal: Int J Surg Pathol. 2010 Oct;18(5):313-8.
Title: Fibrolamellar hepatocellular carcinoma: an immunohistochemical comparison with conventional hepatocellular carcinoma.
Author: Abdul-Al, Hala M|Wang, Guanghua|Makhlouf, Hala R|Goodman, Zachary D
PMID: 20444731
Journal: J Clin Pathol. 2010 Jul;63(7):599-603.
Title: Diagnostic utility of glypican-3 for hepatocellular carcinoma on liver needle biopsy.
Author: Wang, Feng Hua|Yip, Yuk Ching|Zhang, Meng|Vong, Heong Ting|Chan, Kin Iong|Wai, Kit Cheng|Wen, Jian Ming
PMID: 20501450
Journal: Jpn J Clin Oncol. 2010 Sep;40(9):891-6.
Title: Molecular diagnosis of multistage hepatocarcinogenesis.
Author: Sakamoto, Michiie|Effendi, Kathryn|Masugi, Yohei
PMID: 20603246
Journal: World J Gastroenterol. 2010 Jul 28;16(28):3521-8.
Title: Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma.
Author: Akutsu, Noriyuki|Yamamoto, Hiroyuki|Sasaki, Shigeru|Taniguchi, Hiroaki|Arimura, Yoshiaki|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 20653060
Journal: Hepatology. 2010 Nov;52(5):1680-9.
Title: The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.
Author: Lai, Jin-Ping|Oseini, Abdul M|Moser, Catherine D|Yu, Chunrong|Elsawa, Sherine F|Hu, Chunling|Nakamura, Ikuo|Han, Tao|Aderca, Ileana|Isomoto, Hajime|Garrity-Park, Megan M|Shire, Abdirashid M|Li, Jia|Sanderson, Schuyler O|Adjei, Alex A|Fernandez-Zapico, Mar
PMID: 20725905
Journal: J Cell Biochem. 2010 Dec 1;111(5):1252-9.
Title: Glypican 3 binds to GLUT1 and decreases glucose transport activity in hepatocellular carcinoma cells.
Author: Cho, Hye-Sim|Ahn, Jung-Mo|Han, Ho-Jae|Cho, Je-Yoel
PMID: 20803547
Journal: Hepatology. 2010 Sep;52(3):1060-7.
Title: Suppression of liver regeneration and hepatocyte proliferation in hepatocyte-targeted glypican 3 transgenic mice.
Author: Liu, Bowen|Bell, Aaron W|Paranjpe, Shirish|Bowen, William C|Khillan, Jaspal S|Luo, Jian-Hua|Mars, Wendy M|Michalopoulos, George K
PMID: 20812357
Journal: World J Gastroenterol. 2010 Sep 21;16(35):4410-5.
Title: Diagnostic value of glypican-3 in serum and liver for primary hepatocellular carcinoma.
Author: Liu, Hui|Li, Peng|Zhai, Yun|Qu, Chun-Feng|Zhang, Li-Jie|Tan, Yu-Fen|Li, Ning|Ding, Hui-Guo
PMID: 20845507
Journal: Anticancer Drugs. 2010 Nov;21(10):907-16.
Title: Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization.
Author: Nakano, Kiyotaka|Ishiguro, Takahiro|Konishi, Hiroko|Tanaka, Megumi|Sugimoto, Masamichi|Sugo, Izumi|Igawa, Tomoyuki|Tsunoda, Hiroyuki|Kinoshita, Yasuko|Habu, Kiyoshi|Orita, Tetsuro|Tsuchiya, Masayuki|Hattori, Kunihiro|Yamada-Okabe, Hisafumi
PMID: 20847643
Journal: Diagn Pathol. 2010 Sep 25;5:64.
Title: Expression of glypican 3 in placental site trophoblastic tumor.
Author: Ou-Yang, Robin J|Hui, Pei|Yang, Ximing J|Zynger, Debra L
PMID: 20868507
Journal: Nihon Rinsho. 2010 Jul;68 Suppl 7:833-6.
Title: [Assessment of serum GPC3 as a tumor marker for hepatocellular carcinoma and malignant melanoma].
Author: Komori, Hiroyuki|Beppu, Toru|Baba, Hideo|Nakatsura, Tetsuya|Nishimura, Yasuharu
PMID: 20960882
Journal: Anticancer Res. 2010 Dec;30(12):5055-61.
Title: Up-regulation of glypican-3 in human hepatocellular carcinoma.
Author: Suzuki, Masahiro|Sugimoto, Kazushi|Tanaka, Junichiro|Tameda, Masahiko|Inagaki, Yuji|Kusagawa, Satoko|Nojiri, Keiichiro|Beppu, Tetsuya|Yoneda, Kentaro|Yamamoto, Norihiko|Ito, Masaaki|Yoneda, Misao|Uchida, Kazuhiko|Takase, Koujiro|Shiraki, Katsuya
PMID: 21187490
Journal: Liver Int. 2011 Jan;31(1):120-31.
Title: Prognostic significance of circumferential cell surface immunoreactivity of glypican-3 in hepatocellular carcinoma.
Author: Yorita, Kenji|Takahashi, Nobuyasu|Takai, Hirotake|Kato, Atsuhiko|Suzuki, Masami|Ishiguro, Takahiro|Ohtomo, Toshihiko|Nagaike, Koki|Kondo, Kazuhiro|Chijiiwa, Kazuo|Kataoka, Hiroaki
PMID: 20964802
Journal: Pathol Res Pract. 2011 Jan 15;207(1):8-14.
Title: Annexin A2 as a differential diagnostic marker of hepatocellular tumors.
Author: Longerich, Thomas|Haller, Maria Theresia|Mogler, Carolin|Aulmann, Sebastian|Lohmann, Volker|Schirmacher, Peter|Brand, Karsten
PMID: 20971570
Journal: Eur J Cancer. 2011 Feb;47(3):333-8.
Title: Glypican-3: a new target for cancer immunotherapy.
Author: Ho, Mitchell|Kim, Heungnam
PMID: 21112773
Journal: Cancer Sci. 2011 May;102(5):918-25.
Title: HLA-A2-restricted glypican-3 peptide-specific CTL clones induced by peptide vaccine show high avidity and antigen-specific killing activity against tumor cells.
Author: Yoshikawa, Toshiaki|Nakatsugawa, Munehide|Suzuki, Shiro|Shirakawa, Hirofumi|Nobuoka, Daisuke|Sakemura, Noriko|Motomura, Yutaka|Tanaka, Yukie|Hayashi, Shin-Ichi|Nakatsura, Tetsuya
PMID: 21281401
Journal: Mol Imaging. 2011 Feb;10(1):69-77.
Title: Glypican-3 targeting of liver cancer cells using multifunctional nanoparticles.
Author: Park, James O|Stephen, Zachary|Sun, Conroy|Veiseh, Omid|Kievit, Forrest M|Fang, Chen|Leung, Matthew|Mok, Hyejung|Zhang, Miqin
PMID: 21303616
Journal: Gut. 2011 Jul;60(7):967-76.
Title: EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies.
Author: Cai, Mu-Yan|Tong, Zhu-Ting|Zheng, Fang|Liao, Yi-Ji|Wang, Yi|Rao, Hui-Lan|Chen, Yang-Chao|Wu, Qiu-Liang|Liu, Yan-Hui|Guan, Xin-Yuan|Lin, Marie C|Zeng, Yi-Xin|Kung, Hsiang-Fu|Xie, Dan
PMID: 21330577
Journal: Ann Diagn Pathol. 2011 Jun;15(3):162-9.
Title: Expression and clinicopathologic significance of glypican 3 in hepatocellular carcinoma.
Author: Yan, Bin|Wei, Jing-Jing|Qian, Yi-Ming|Zhao, Xiang-Li|Zhang, Wei-Wei|Xu, Ai-Min|Zhang, Shu-Hui
PMID: 21371925
Journal: Zhonghua Bing Li Xue Za Zhi. 2011 Jan;40(1):11-6.
Title: [Expression and clinicopathologic significance of GPC3 and other antibodies in well-differentiated hepatocellular carcinoma].
Author: DU, Jing-li|Wei, Li-xin|Wang, Yu-lan
PMID: 21429352
Journal: BMC Cancer. 2011 Mar 28;11:111.
Title: Seminal vesicle metastasis after partial hepatectomy for hepatocellular carcinoma.
Author: Gong, Li|Zheng, Minwen|Li, Yanhong|Zhang, Wendong|Bu, Wangjun|Shi, Lifang|Zhang, Wei|Yan, Hong
PMID: 21443783
Journal: Hepatobiliary Pancreat Dis Int. 2011 Apr;10(2):164-70.
Title: GPC3 fused to an alpha epitope of HBsAg acts as an immune target against hepatocellular carcinoma associated with hepatitis B virus.
Author: Yang, Jun-Wen|Yang, Dong-Ye|Lu, Fang-Gen|Li, Cai-Hong|Chen, Hui|Xie, Ning|Zhao, Xin
PMID: 21459723
Journal: Hepatology. 2011 May;53(5):1549-57.
Title: Diagnostic accuracy of clathrin heavy chain staining in a marker panel for the diagnosis of small hepatocellular carcinoma.
Author: Di Tommaso, Luca|Destro, Annarita|Fabbris, Valentina|Spagnuolo, Gaia|Laura Fracanzani, Anna|Fargion, Silvia|Maggioni, Marco|Patriarca, Carlo|Maria Macchi, Roberto|Quagliuolo, Michela|Borzio, Mauro|Iavarone, Massimo|Sangiovanni, Angelo|Colombo, Massimo|Ron
PMID: 21520170
Journal: Anticancer Agents Med Chem. 2011 Jul;11(6):543-8.
Title: Therapeutic potential of targeting glypican-3 in hepatocellular carcinoma.
Author: Allegretta, Mark|Filmus, Jorge
PMID: 21554204
Journal: Int J Mol Med. 2011 Oct;28(4):497-503.
Title: Inhibition of glypican-3 expression via RNA interference influences the growth and invasive ability of the MHCC97-H human hepatocellular carcinoma cell line.
Author: Ruan, Jian|Liu, Feiye|Chen, Xiaohua|Zhao, Peng|Su, Ning|Xie, Guozhu|Chen, Jianpeng|Zheng, Dayong|Luo, Rongcheng
PMID: 21617840
Journal: Cancer Sci. 2011 Sep;102(9):1622-9.
Title: Glypican-3 could be an effective target for immunotherapy combined with chemotherapy against ovarian clear cell carcinoma.
Author: Suzuki, Shiro|Yoshikawa, Toshiaki|Hirosawa, Tomoya|Shibata, Kiyosumi|Kikkawa, Fumitaka|Akatsuka, Yoshiki|Nakatsura, Tetsuya
PMID: 21668581
Journal: Neoplasia. 2011 Aug;13(8):735-47.
Title: Suppression of glypican 3 inhibits growth of hepatocellular carcinoma cells through up-regulation of TGF-beta2.
Author: Sun, Chris K|Chua, Mei-Sze|He, Jing|So, Samuel K
PMID: 21847365
Journal: Mol Med Rep. 2011 Nov-Dec;4(6):1067-73.
Title: A new membrane re-anchored protein originating from GPC3 against hepatoma cells HepG2.
Author: Yang, Dongye|Yang, Junwen|Lu, Fanggen|Li, Caihong|Yang, Jingbo|Liang, Jieling
PMID: 21904776
Journal: J Clin Lab Anal. 2011;25(5):350-3.
Title: Diagnostic and prognostic role of serum glypican 3 in patients with hepatocellular carcinoma.
Author: Ozkan, Hasan|Erdal, Harun|Kocak, Erdem|Tutkak, Huseyin|Karaeren, Zihni|Yakut, Mustafa|Koklu, Seyfettin
PMID: 21919070
Journal: BioDrugs. 2011 Oct 1;25(5):275-84.
Title: Advances in liver cancer antibody therapies: a focus on glypican-3 and mesothelin.
Author: Ho, Mitchell
PMID: 21942912
Journal: Hepat Mon. 2011 Mar;11(3):195-9.
Title: Clinical values of AFP, GPC3 mRNA in peripheral blood for prediction of hepatocellular carcinoma recurrence following OLT: AFP, GPC3 mRNA for prediction of HCC.
Author: Wang, Yuliang|Shen, Zhongyang|Zhu, Zhijun|Han, Ruifa|Huai, Mingsheng
PMID: 22087143
Journal: Zhonghua Bing Li Xue Za Zhi. 2011 Sep;40(9):626-9.
Title: [Significance of glypican-3 immunohistochemistry in diagnosis of hepatocellular carcinoma].
Author: Yip, Yuk-ching|Wang, Feng-hua|Vong, Heong-ting|Zhang, Meng|Wen, Jian-ming
PMID: 22177248
Journal: Cancer Rep. 2011;1(1):14-19.
Title: The role of glypican-3 in regulating Wnt in hepatocellular carcinomas.
Author: Gao, Wei|Ho, Mitchell
PMID: 22563565
Journal: Cancer Biomark. 2011-2012;11(1):29-39.
Title: Application of HBx-induced anti-URGs as early warning biomarker of cirrhosis and HCC.
Author: Wang, Wen|Zhao, Lan-Juan|Wang, Yan|Tao, Qing-Yuan|Feitelson, Mark A|Zhao, Ping|Ren, Hao|Qi, Zhong-Tian
PMID: 22820138
Journal: J Pharm Anal. 2011 Aug;1(3):166-174.
Title: Chemiluminescence enzyme immunoassay based on magnetic nanoparticles for detection of hepatocellular carcinoma marker glypican-3.
Author: Zhang, Qian-Yun|Chen, Hui|Lin, Zhen|Lin, Jin-Ming
PMID: 29403695
Journal: Mol Biol Rep. 2012 Jan;39(1):351-7.
Title: Glypican-3, a novel prognostic marker of hepatocellular cancer, is related with postoperative metastasis and recurrence in hepatocellular cancer patients.
Author: Ning, Su|Bin, Chen|Na, Huang|Peng, Shen|Yi, Ding|Xiang-hua, Ye|Fang-yin, Zeng|Da-yong, Zheng|Rong-cheng, Luo
PMID: 21655958
Journal: Ann Surg Oncol. 2012 Jul;19 Suppl 3:S455-63.
Title: Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin.
Author: Yu, Ming-Chin|Lee, Yun-Shien|Lin, Sey-En|Wu, Hsiang-Yao|Chen, Tse-Ching|Lee, Wei-Chen|Chen, Miin-Fu|Tsai, Chi-Neu
PMID: 21822558
Journal: Int J Oncol. 2012 Jan;40(1):63-70.
Title: Radiofrequency ablation for hepatocellular carcinoma induces glypican-3 peptide-specific cytotoxic T lymphocytes.
Author: Nobuoka, Daisuke|Motomura, Yutaka|Shirakawa, Hirofumi|Yoshikawa, Toshiaki|Kuronuma, Toshimitsu|Takahashi, Mari|Nakachi, Kohei|Ishii, Hiroshi|Furuse, Junji|Gotohda, Naoto|Takahashi, Shinichiro|Nakagohri, Toshio|Konishi, Masaru|Kinoshita, Taira|Komori, Hiro
PMID: 21922136
Journal: Hum Pathol. 2012 May;43(5):695-701.
Title: Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver.
Author: Levy, Mary|Trivedi, Anand|Zhang, Jun|Miles, Lili|Mattis, Aras N|Kim, Grace E|Lassman, Charles|Anders, Robert A|Misdraji, Joseph|Yerian, Lisa M|Xu, Haodong|Dhall, Deepti|Wang, Hanlin L
PMID: 21937079
Journal: Acta Histochem. 2012 Oct;114(6):547-52.
Title: Glypican-3 as a potential differential diagnosis marker for hepatocellular carcinoma: a tissue microarray-based study.
Author: Zhang, Lijie|Liu, Hui|Sun, Lin|Li, Ning|Ding, Huiguo|Zheng, Jie
PMID: 22119409
Journal: Gut. 2012 Oct;61(10):1481-7.
Title: Prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for diagnosis of very early hepatocellular carcinoma.
Author: Tremosini, Silvia|Forner, Alejandro|Boix, Loreto|Vilana, Ramon|Bianchi, Luis|Reig, Maria|Rimola, Jordi|Rodriguez-Lope, Carlos|Ayuso, Carmen|Sole, Manel|Bruix, Jordi
PMID: 22287594
Journal: Biochem Biophys Res Commun. 2012 Mar 23;419(4):656-61.
Title: Silencing glypican-3 expression induces apoptosis in human hepatocellular carcinoma cells.
Author: Liu, Shiyuan|Li, Yumin|Chen, Wei|Zheng, Pengfei|Liu, Tao|He, Wenting|Zhang, Junqiang|Zeng, Xiangting
PMID: 22382024
Journal: FEBS Lett. 2012 Mar 23;586(6):884-91.
Title: MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3.
Author: Huang, Na|Lin, Jing|Ruan, Jian|Su, Ning|Qing, Ruzhai|Liu, Feiye|He, Benfu|Lv, Chengwei|Zheng, Dayong|Luo, Rongcheng
PMID: 22449976
Journal: BMC Biotechnol. 2012 May 7;12:23.
Title: Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library.
Author: Li, Yonghai|Siegel, Donald L|Scholler, Nathalie|Kaplan, David E
PMID: 22564378
Journal: Clin Cancer Res. 2012 Jul 1;18(13):3686-96.
Title: Phase I trial of a glypican-3-derived peptide vaccine for advanced hepatocellular carcinoma: immunologic evidence and potential for improving overall survival.
Author: Sawada, Yu|Yoshikawa, Toshiaki|Nobuoka, Daisuke|Shirakawa, Hirofumi|Kuronuma, Toshimitsu|Motomura, Yutaka|Mizuno, Shoichi|Ishii, Hiroshi|Nakachi, Kohei|Konishi, Masaru|Nakagohri, Toshio|Takahashi, Shinichiro|Gotohda, Naoto|Takayama, Tadatoshi|Yamao, Kenji
PMID: 22577059
Journal: PLoS One. 2012;7(5):e37159.
Title: Gene expression profiling of liver cancer stem cells by RNA-sequencing.
Author: Ho, David W Y|Yang, Zhen Fan|Yi, Kang|Lam, Chi Tat|Ng, Michael N P|Yu, Wan Ching|Lau, Joyce|Wan, Timothy|Wang, Xiaoqi|Yan, Zhixiang|Liu, Hang|Zhang, Yong|Fan, Sheung Tat
PMID: 22606345
Journal: World J Gastroenterol. 2012 May 21;18(19):2408-14.
Title: Glypican-3 expression and its relationship with recurrence of HCC after liver transplantation.
Author: Wang, Yu-Liang|Zhu, Zhi-Jun|Teng, Da-Hong|Yao, Zhi|Gao, Wei|Shen, Zhong-Yang
PMID: 22654434
Journal: Hepatology. 2012 Oct;56(4):1380-90.
Title: Oncogenic activation of glypican-3 by c-Myc in human hepatocellular carcinoma.
Author: Li, Li|Jin, Ronghua|Zhang, Xiaoli|Lv, Fudong|Liu, Lifeng|Liu, Daojie|Liu, Kai|Li, Ning|Chen, Dexi
PMID: 22706665
Journal: MAbs. 2012 Sep-Oct;4(5):592-9.
Title: High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening.
Author: Phung, Yen|Gao, Wei|Man, Yan-Gao|Nagata, Satoshi|Ho, Mitchell
PMID: 22820551
Journal: Int J Nanomedicine. 2012;7:4593-611.
Title: Preparation and in vitro studies of MRI-specific superparamagnetic iron oxide antiGPC3 probe for hepatocellular carcinoma.
Author: Li, Youwei|Chen, Zhengguang|Li, Fei|Wang, Jichen|Zhang, Zongming
PMID: 22956868
Journal: Tumori. 2012 Jul-Aug;98(4):478-84.
Title: Comparative analysis of immunohistochemical markers for differential diagnosis of hepatocelluar carcinoma and cholangiocarcinoma.
Author: Ryu, Han Suk|Lee, Kyounbun|Shin, Eun|Kim, Soo Hee|Jing, Jin|Jung, Hae Yeon|Lee, Hyebin|Jang, Ja-June
PMID: 23052165
Journal: Nutr Diabetes. 2012 Dec 3;2:e52.
Title: Conditioned media from (pre)adipocytes stimulate fibrinogen and PAI-1 production by HepG2 hepatoma cells.
Author: Faber, D R|Kalkhoven, E|Westerink, J|Bouwman, J J|Monajemi, H M|Visseren, F L J
PMID: 23208413
Journal: Oncoimmunology. 2012 Nov 1;1(8):1448-1450.
Title: A glypican-3-derived peptide vaccine against hepatocellular carcinoma.
Author: Sawada, Yu|Sakai, Mayuko|Yoshikawa, Toshiaki|Ofuji, Kazuya|Nakatsura, Tetsuya
PMID: 23243625
Journal: Hybridoma (Larchmt). 2012 Dec;31(6):455-61.
Title: Preparation and characterization of monoclonal antibody against glypican-3.
Author: Ma, Rui-juan|Wang, Sui-hai|Qin, Shi-ni|Wang, Xiao-bo|Li, Gao-fei|Li, Ming|Xu, Wei-wen
PMID: 23244326
Journal: Nihon Rinsho. 2012 Dec;70(12):2136-41.
Title: [The cancer specific antigen, glypican-3 (GPC3)-targeted immunotherapy].
Author: Sawada, Yu|Nakatsura, Tetsuya
PMID: 23259386
Journal: Cancers (Basel). 2012 Sep 1;4(3):945-68.
Title: The expression of embryonic liver development genes in hepatitis C induced cirrhosis and hepatocellular carcinoma.
Author: Behnke, Martha|Reimers, Mark|Fisher, Robert
PMID: 23667740
Journal: Hepatology. 2013 Jan;57(1):195-204.
Title: A functional screening identifies five microRNAs controlling glypican-3: role of miR-1271 down-regulation in hepatocellular carcinoma.
Author: Maurel, Marion|Jalvy, Sandra|Ladeiro, Yannick|Combe, Chantal|Vachet, Laetitia|Sagliocco, Francis|Bioulac-Sage, Paulette|Pitard, Vincent|Jacquemin-Sablon, Helene|Zucman-Rossi, Jessica|Laloo, Benoit|Grosset, Christophe F
PMID: 22865282
Journal: J Cell Biochem. 2013 Mar;114(3):625-31.
Title: Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.
Author: Miao, Hui-Lai|Pan, Zhi-Jian|Lei, Chang-Jiang|Wen, Ji-Yu|Li, Ming-Yi|Liu, Zhong-Kao|Qiu, Zhi-Dong|Lin, Man-Zhou|Chen, Nian-Ping|Chen, Ming
PMID: 23060277
Journal: Hum Pathol. 2013 Apr;44(4):542-50.
Title: Glypican-3 expression in gastrointestinal and pancreatic epithelial neoplasms.
Author: Mounajjed, Taofic|Zhang, Lizhi|Wu, Tsung-Teh
PMID: 23079207
Journal: FEBS J. 2013 May;280(10):2471-6.
Title: Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma.
Author: Filmus, Jorge|Capurro, Mariana
PMID: 23305321
Journal: Int J Oncol. 2013 Mar;42(3):831-8.
Title: Identification of an H2-Kb or H2-Db restricted and glypican-3-derived cytotoxic T-lymphocyte epitope peptide.
Author: Iwama, Tatsuaki|Horie, Kazutaka|Yoshikawa, Toshiaki|Nobuoka, Daisuke|Shimomura, Manami|Sawada, Yu|Nakatsura, Tetsuya
PMID: 23354275
Journal: Clin Cancer Res. 2013 Feb 15;19(4):920-8.
Title: First-in-man phase I study of GC33, a novel recombinant humanized antibody against glypican-3, in patients with advanced hepatocellular carcinoma.
Author: Zhu, Andrew X|Gold, Philip J|El-Khoueiry, Anthony B|Abrams, Thomas A|Morikawa, Hideo|Ohishi, Norihisa|Ohtomo, Toshihiko|Philip, Philip A
PMID: 23362325
Journal: Anal Chem. 2013 Mar 19;85(6):3166-73.
Title: Highly specific and ultrasensitive graphene-enhanced electrochemical detection of low-abundance tumor cells using silica nanoparticles coated with antibody-conjugated quantum dots.
Author: Wu, Yafeng|Xue, Peng|Kang, Yuejun|Hui, Kam M
PMID: 23402311
Journal: Hum Vaccin Immunother. 2013 Jan;9(1):210-2.
Title: Peptide vaccines for hepatocellular carcinoma.
Author: Nobuoka, Daisuke|Yoshikawa, Toshiaki|Sawada, Yu|Fujiwara, Toshiyoshi|Nakatsura, Tetsuya
PMID: 23442593
Journal: Hum Vaccin Immunother. 2013 Jun;9(6):1228-33.
Title: Remarkable tumor lysis in a hepatocellular carcinoma patient immediately following glypican-3-derived peptide vaccination: an autopsy case.
Author: Sawada, Yu|Yoshikawa, Toshiaki|Fujii, Satoshi|Mitsunaga, Shuichi|Nobuoka, Daisuke|Mizuno, Shoichi|Takahashi, Mari|Yamauchi, Chisako|Endo, Itaru|Nakatsura, Tetsuya
PMID: 23466818
Journal: Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):E1083-91.
Title: Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma.
Author: Feng, Mingqian|Gao, Wei|Wang, Ruoqi|Chen, Weizao|Man, Yan-Gao|Figg, William Douglas|Wang, Xin Wei|Dimitrov, Dimiter S|Ho, Mitchell
PMID: 23471984
Journal: Sci China Life Sci. 2013 Mar;56(3):234-9.
Title: Clinical application of specific antibody against glypican-3 for hepatocellular carcinoma diagnosis.
Author: Yu, Juanping|Ma, Qiang|Zhang, Bin|Ma, Ruijuan|Xu, Xiguang|Li, Mingsong|Xu, Weiwen|Li, Ming
PMID: 23526389
Journal: BMC Cancer. 2013 Mar 27;13:161.
Title: A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values.
Author: Jin, Guang-Zhi|Dong, Hui|Yu, Wen-Long|Li, Yan|Lu, Xin-Yuan|Yu, Hua|Xian, Zhi-Hong|Dong, Wei|Liu, Yin-Kun|Cong, Wen-Ming|Wu, Meng-Chao
PMID: 23537217
Journal: Surgery. 2013 Sep;154(3):536-44.
Title: Glypican-3 is a potential prognostic biomarker for hepatocellular carcinoma after curative resection.
Author: Fu, Shun-Jun|Qi, Chao-Ying|Xiao, Wei-Kai|Li, Shao-Qiang|Peng, Bao-Gang|Liang, Li-Jian
PMID: 23601901
Journal: Clin Chim Acta. 2013 Aug 23;423:105-11.
Title: Reevaluation of glypican-3 as a serological marker for hepatocellular carcinoma.
Author: Chen, Min|Li, Guohua|Yan, Jian|Lu, Xiuzhi|Cui, Jianwei|Ni, Zhengxian|Cheng, Weizhong|Qian, Gengsun|Zhang, Jing|Tu, Hong
PMID: 23643963
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Apr;33(4):590-2, 597.
Title: [Relationship between glypican-3 and Notch1 expressions in hepatocellular carcinoma].
Author: Peng, Fanli|Wu, Ziqing|Li, Xuenong
PMID: 23644127
Journal: Zhonghua Gan Zang Bing Za Zhi. 2013 Jan;21(1):53-6.
Title: [Preparation and in vitro study of a high molecular weight contrast agent targeting hepatoma cells].
Author: Yang, Jing|Zeng, Yan|Guo, Da-Jing|Fang, Zheng|Zhao, Jian-Nong|Wang, Zhi-Gang
PMID: 23663764
Journal: J Histochem Cytochem. 2013 Sep;61(9):639-48.
Title: Diagnostic value of immunohistochemical staining of GP73, GPC3, DCP, CD34, CD31, and reticulin staining in hepatocellular carcinoma.
Author: Yao, Shuzhe|Zhang, Jianping|Chen, Haiyan|Sheng, Yan|Zhang, Xiaoying|Liu, Zhiyan|Zhang, Cuijuan
PMID: 23686365
Journal: Am J Surg Pathol. 2013 Jul;37(7):1058-66.
Title: Multifocal hepatic neoplasia in 3 children with APC gene mutation.
Author: Gupta, Anita|Sheridan, Rachel M|Towbin, Alexander|Geller, James I|Tiao, Gregory|Bove, Kevin E
PMID: 23715166
Journal: J Cancer Res Clin Oncol. 2013 Aug;139(8):1417-24.
Title: A comparison of glypican-3 with alpha-fetoprotein as a serum marker for hepatocellular carcinoma: a meta-analysis.
Author: Xu, Cheng|Yan, Zhehui|Zhou, Liang|Wang, Yuming
PMID: 23743582
Journal: Br J Cancer. 2013 Aug 20;109(4):1031-9.
Title: Expression pattern of tumour-associated antigens in hepatocellular carcinoma: association with immune infiltration and disease progression.
Author: Liang, J|Ding, T|Guo, Z-W|Yu, X-J|Hu, Y-Z|Zheng, L|Xu, J
PMID: 23868000
Journal: Int J Oncol. 2013 Oct;43(4):1019-26.
Title: Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican3derived peptide.
Author: Tada, Yoshitaka|Yoshikawa, Toshiaki|Shimomura, Manami|Sawada, Yu|Sakai, Mayuko|Shirakawa, Hirofumi|Nobuoka, Daisuke|Nakatsura, Tetsuya
PMID: 23903757
Journal: Mol Biol Rep. 2013 Dec;40(12):7069-75.
Title: Evaluation of circulating Transforming growth factor-beta1, Glypican-3 and Golgi protein-73 mRNAs expression as predictive markers for hepatocellular carcinoma in Egyptian patients.
Author: Ibrahim, Gehan H|Mahmoud, Moushira A|Aly, Nagwa M
PMID: 24186850
Journal: J Egypt Natl Canc Inst. 2013 Dec;25(4):173-80.
Title: Role of glypican-3 immunocytochemistry in differentiating hepatocellular carcinoma from metastatic carcinoma of the liver utilizing fine needle aspiration cytology.
Author: Zaakook, Mohamed|Ayoub, Menar|Sinna, Eman Abu|El-Sheikh, Samar
PMID: 24207089
Journal: Am J Clin Pathol. 2013 Dec;140(6):872-80.
Title: Immunohistochemistry for the novel markers glypican 3, PAX8, and p40 (DeltaNp63) in squamous cell and urothelial carcinoma.
Author: Gailey, Michael P|Bellizzi, Andrew M
PMID: 24225756
Journal: Afr Health Sci. 2013 Sep;13(3):703-9.
Title: Diagnostic value of glypican-3 in alpha fetoprotein negative hepatocellular carcinoma patients.
Author: Li, B|Liu, H|Shang, H W|Li, P|Li, N|Ding, H G
PMID: 24250310
Journal: J Gastrointestin Liver Dis. 2013 Dec;22(4):419-25.
Title: New genetic markers for diagnosis of hepatitis C related hepatocellular carcinoma in Egyptian patients.
Author: Saad, Yasmin|El-Serafy, Magdy|Eldin, Mona S|Abdellatif, Zeinab|Khatab, Hany|Elbaz, Tamer|Elgarem, Hasan
PMID: 24369324
Journal: Asian Pac J Cancer Prev. 2013;14(12):7345-9.
Title: Can Glypican3 be diagnostic for early hepatocellular carcinoma among Egyptian patients?
Author: Abdelgawad, Iman Attia|Mossallam, Ghada Ibrahim|Radwan, Noha Hassan|Elzawahry, Heba Mohammed|Elhifnawy, Niveen Mostafa
PMID: 24460300
Journal: J Gastroenterol. 2014 Jan;49(1):117-25.
Title: Positive glypican-3 expression in early hepatocellular carcinoma predicts recurrence after hepatectomy.
Author: Chen, I-Pei|Ariizumi, Shun-ichi|Nakano, Masayuki|Yamamoto, Masakazu
PMID: 23532638
Journal: Hepatol Res. 2014 Mar;44(3):338-48.
Title: MicroRNA-520c-3p inhibits hepatocellular carcinoma cell proliferation and invasion through induction of cell apoptosis by targeting glypican-3.
Author: Miao, Hui-Lai|Lei, Chang-Jiang|Qiu, Zhi-Dong|Liu, Zhong-Kao|Li, Ran|Bao, Shi-Ting|Li, Ming-Yi
PMID: 23607462
Journal: FEBS Lett. 2014 Jan 21;588(2):377-82.
Title: Glypican-3 antibodies: a new therapeutic target for liver cancer.
Author: Feng, Mingqian|Ho, Mitchell
PMID: 24140348
Journal: Hum Vaccin Immunother. 2014;10(2):338-43.
Title: Significant clinical response of progressive recurrent ovarian clear cell carcinoma to glypican-3-derived peptide vaccine therapy: two case reports.
Author: Suzuki, Shiro|Shibata, Kiyosumi|Kikkawa, Fumitaka|Nakatsura, Tetsuya
PMID: 24252799
Journal: Liver Int. 2014 Jul;34(6):942-52.
Title: Aberrant expression of monocarboxylate transporter 4 in tumour cells predicts an unfavourable outcome in patients with hepatocellular carcinoma.
Author: Ohno, Akinobu|Yorita, Kenji|Haruyama, Yukihiro|Kondo, Kazuhiro|Kato, Atsuhiko|Ohtomo, Toshihiko|Kawaguchi, Makiko|Marutuska, Kousuke|Chijiiwa, Kazuo|Kataoka, Hiroaki
PMID: 24433439
Journal: J Surg Res. 2014 Apr;187(2):377-85.
Title: The glypican 3 hepatocellular carcinoma marker regulates human hepatic stellate cells via Hedgehog signaling.
Author: Magistri, Paolo|Leonard, Stephanie Y|Tang, Chih-Min|Chan, Jonathan C|Lee, Tracy E|Sicklick, Jason K
PMID: 24439425
Journal: PLoS One. 2014 Jan 13;9(1):e84807.
Title: Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent manners.
Author: Chiba, Tetsuhiro|Suzuki, Eiichiro|Yuki, Kaori|Zen, Yoh|Oshima, Motohiko|Miyagi, Satoru|Saraya, Atsunori|Koide, Shuhei|Motoyama, Tenyu|Ogasawara, Sadahisa|Ooka, Yoshihiko|Tawada, Akinobu|Nakatsura, Tetsuya|Hayashi, Takehiro|Yamashita, Taro|Kaneko, Syuichi|
PMID: 24454751
Journal: Hepatology. 2014 Aug;60(2):576-87.
Title: Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy.
Author: Gao, Wei|Kim, Heungnam|Feng, Mingqian|Phung, Yen|Xavier, Charles P|Rubin, Jeffrey S|Ho, Mitchell
PMID: 24492943
Journal: J Cell Sci. 2014 Apr 1;127(Pt 7):1565-75.
Title: Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling.
Author: Capurro, Mariana|Martin, Tonya|Shi, Wen|Filmus, Jorge
PMID: 24496449
Journal: PLoS One. 2014 Jan 31;9(1):e87120.
Title: Dysplastic nodules with glypican-3 positive immunostaining: a risk for early hepatocellular carcinoma.
Author: Gong, Li|Wei, Long-Xiao|Ren, Pin|Zhang, Wen-Dong|Liu, Xiao-Yan|Han, Xiu-Juan|Yao, Li|Zhu, Shao-Jun|Lan, Miao|Li, Yan-Hong|Zhang, Wei
PMID: 24498024
Journal: Cancer Sci. 2014 Apr;105(4):455-62.
Title: Japanese phase I study of GC33, a humanized antibody against glypican-3 for advanced hepatocellular carcinoma.
Author: Ikeda, Masafumi|Ohkawa, Shinichi|Okusaka, Takuji|Mitsunaga, Shuichi|Kobayashi, Satoshi|Morizane, Chigusa|Suzuki, Ikue|Yamamoto, Shunsuke|Furuse, Junji
PMID: 24521523
Journal: BMC Cancer. 2014 Feb 18;14:104.
Title: Prognostic significance of glypican-3 in hepatocellular carcinoma: a meta-analysis.
Author: Xiao, Wei-Kai|Qi, Chao-Ying|Chen, Dong|Li, Shao-Qiang|Fu, Shun-Jun|Peng, Bao-Gang|Liang, Li-Jian
PMID: 24548704
Journal: J Nucl Med. 2014 May;55(5):799-804.
Title: Glypican-3-targeted 89Zr PET imaging of hepatocellular carcinoma.
Author: Sham, Jonathan G|Kievit, Forrest M|Grierson, John R|Miyaoka, Robert S|Yeh, Matthew M|Zhang, Miqin|Yeung, Raymond S|Minoshima, Satoshi|Park, James O
PMID: 24627434
Journal: Gut Liver. 2014 Mar;8(2):177-85.
Title: Clinical utility of plasma glypican-3 and osteopontin as biomarkers of hepatocellular carcinoma.
Author: Lee, Hyun Jung|Yeon, Jong Eun|Suh, Sang Jun|Lee, Sun Jae|Yoon, Eileen L|Kang, Keunhee|Yoo, Yang Jae|Kim, Ji Hoon|Seo, Yeon Seok|Yim, Hyung Joon|Byun, Kwan Soo
PMID: 24672660
Journal: PLoS One. 2014 Apr 1;9(4):e93599.
Title: Maotai ameliorates diethylnitrosamine-initiated hepatocellular carcinoma formation in mice.
Author: Yi, Xu|Long, Li|Yang, Chunzhang|Lu, Yingying|Cheng, Mingliang
PMID: 24690765
Journal: Zhonghua Gan Zang Bing Za Zhi. 2014 Feb;22(2):142-7.
Title: [Preparation of a glypican-3-targeting hepatocellular carcinoma MR probe and its molecular imaging in HepG2 cells].
Author: Gu, Yan|Zeng, Yan|Guo, Da-Jing|Yang, Jing|Zhou, Jun|Liu, Xin-Jie|Wang, Zhi-Gang
PMID: 24735598
Journal: Biomaterials. 2014 Aug;35(25):6964-71.
Title: Imaging of hepatocellular carcinoma patient-derived xenografts using (8)(9)Zr-labeled anti-glypican-3 monoclonal antibody.
Author: Yang, Xiaoyang|Liu, Hongguang|Sun, Chris K|Natarajan, Arutselvan|Hu, Xiang|Wang, Xiaolin|Allegretta, Mark|Guttmann, Ronald D|Gambhir, Sanjiv S|Chua, Mei-Sze|Cheng, Zhen|So, Samuel K
PMID: 24836949
Journal: World J Gastroenterol. 2014 May 28;20(20):6336-44.
Title: Prognostic and clinicopathological significance of glypican-3 overexpression in hepatocellular carcinoma: a meta-analysis.
Author: Li, Jia|Gao, Jian-Zhi|Du, Jing-Li|Wei, Li-Xin
PMID: 24876756
Journal: Hepatogastroenterology. 2014 Mar-Apr;61(130):278-84.
Title: GPC3 DNA vaccine elicits potent cellular antitumor immunity against HCC in mice.
Author: Li, Shao-Qiang|Lin, Jie|Qi, Chao-Ying|Fu, Shun-Jun|Xiao, Wei-Kai|Peng, Bao-Gang|Liang, Li-Jian
PMID: 24901124
Journal: Analyst. 2014 Aug 7;139(15):3744-7.
Title: A sensitive method for protein assays using a peptide-based nano-label: human glypican-3 detection for hepatocellular carcinomas diagnosis.
Author: Huang, Yue|Li, Hao|Gao, Tao|Liu, Xinjian|Li, Genxi
PMID: 24909227
Journal: World J Gastroenterol. 2014 May 21;20(19):5826-38.
Title: Identification of biomarkers for hepatocellular carcinoma by semiquantitative immunocytochemistry.
Author: Mu, Hong|Lin, Kai-Xuan|Zhao, Hong|Xing, Shu|Li, Cong|Liu, Fang|Lu, Hai-Zhen|Zhang, Ze|Sun, Yu-Lin|Yan, Xi-Yun|Cai, Jian-Qiang|Zhao, Xiao-Hang
PMID: 24914343
Journal: Zhonghua Bing Li Xue Za Zhi. 2014 Apr;43(4):246-50.
Title: [Significance of arginase-1, glypican-3, hepatocyte paraffin antigen 1 and alpha-fetoprotein in diagnosis and differential diagnosis of liver tumors].
Author: Li, Jie|Wei, Lixin
PMID: 24915815
Journal: Cancer Chemother Pharmacol. 2014 Aug;74(2):323-32.
Title: Circulating biomarkers in hepatocellular carcinoma.
Author: Morris, Karen L|Tugwood, Jonathan D|Khoja, Leila|Lancashire, Matthew|Sloane, Robert|Burt, Debbie|Shenjere, Patrick|Zhou, Cong|Hodgson, Clare|Ohtomo, Toshihiko|Katoh, Atsuhiko|Ishiguro, Takahiro|Valle, Juan W|Dive, Caroline
PMID: 24923562
Journal: Asian Pac J Trop Med. 2014 Oct;7(10):780-6.
Title: Lentivirus vectors construction of SiRNA targeting interference GPC3 gene and its biological effects on liver cancer cell lines Huh-7.
Author: Lei, Chang-Jiang|Yao, Chun|Pan, Qing-Yun|Long, Hao-Cheng|Li, Lei|Zheng, Shu-Ping|Zeng, Cheng|Huang, Jian-Bin
PMID: 25129460
Journal: Int J Biochem Cell Biol. 2014 Oct;55:129-35.
Title: Reduced nucleic ZHX2 involves in oncogenic activation of glypican 3 in human hepatocellular carcinoma.
Author: Luan, Fang|Liu, Peng|Ma, Hongxin|Yue, Xuetian|Liu, Jun|Gao, Lifen|Liang, Xiaohong|Ma, Chunhong
PMID: 25195714
Journal: Mol Med Rep. 2014 Dec;10(6):3177-84.
Title: Silencing of the glypican-3 gene affects the biological behavior of human hepatocellular carcinoma cells.
Author: Qi, Xin-Hui|Wu, Di|Cui, Hui-Xia|Ma, Nan|Su, Jia|Wang, Yu-Tong|Jiang, You-Hong
PMID: 25270552
Journal: Clin Cancer Res. 2014 Dec 15;20(24):6418-28.
Title: Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma.
Author: Gao, Huiping|Li, Kesang|Tu, Hong|Pan, Xiaorong|Jiang, Hua|Shi, Bizhi|Kong, Juan|Wang, Hongyang|Yang, Shengli|Gu, Jianren|Li, Zonghai
PMID: 25320357
Journal: J Nucl Med. 2014 Dec;55(12):2032-7.
Title: Glypican-3-targeting F(ab')2 for 89Zr PET of hepatocellular carcinoma.
Author: Sham, Jonathan G|Kievit, Forrest M|Grierson, John R|Chiarelli, Peter A|Miyaoka, Robert S|Zhang, Miqin|Yeung, Raymond S|Minoshima, Satoshi|Park, James O
PMID: 25359880
Journal: Dis Markers. 2014;2014:127831.
Title: Can serum glypican-3 be a biomarker for effective diagnosis of hepatocellular carcinoma? A meta-analysis of the literature.
Author: Yang, Sheng-Li|Fang, Xiefan|Huang, Zao-Zao|Liu, Xiang-Jie|Xiong, Zhi-Fan|Liu, Ping|Yao, Hong-Yi|Li, Chang-Hai
PMID: 25378766
Journal: Arch Med Res. 2014 Oct;45(7):580-8.
Title: Diagnosis accuracy of serum glypican-3 in patients with hepatocellular carcinoma: a systematic review with meta-analysis.
Author: Jia, Xiaobo|Liu, Jiao|Gao, Yingtang|Huang, Yong|Du, Zhi
PMID: 25446613
Journal: J Hepatocell Carcinoma. 2014 May 21;1:35-42.
Title: Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma.
Author: Ofuji, Kazuya|Saito, Keigo|Yoshikawa, Toshiaki|Nakatsura, Tetsuya
PMID: 27508174
Journal: J Clin Lab Anal. 2015 Mar;29(2):85-93.
Title: Development of a clinical chemiluminescent immunoassay for serum GPC3 and simultaneous measurements alone with AFP and CK19 in diagnosis of hepatocellular carcinoma.
Author: Yu, Juan-Ping|Xu, Xi-Guang|Ma, Rui-Juan|Qin, Shi-Ni|Wang, Cong-Rong|Wang, Xiao-Bo|Li, Ming|Li, Ming-Song|Ma, Qiang|Xu, Wei-Wen
PMID: 24687454
Journal: Pathol Oncol Res. 2015 Apr;21(2):379-87.
Title: Immunohistochemical Study of Glypican-3 and HepPar-1 in Differentiating Hepatocellular Carcinoma from Metastatic Carcinomas in FNA of the Liver.
Author: Ibrahim, Taiseer R|Abdel-Raouf, Samar M
PMID: 25108409
Journal: Eur J Pediatr Surg. 2015 Feb;25(1):138-44.
Title: Glypican 3 expression in pediatric malignant solid tumors.
Author: Kinoshita, Yoshiaki|Tanaka, Sakura|Souzaki, Ryota|Miyoshi, Kina|Kohashi, Kenichi|Oda, Yoshinao|Nakatsura, Tetsuya|Taguchi, Tomoaki
PMID: 25344940
Journal: Int J Oncol. 2015 Jan;46(1):28-36.
Title: Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes.
Author: Sawada, Yu|Yoshikawa, Toshiaki|Shimomura, Manami|Iwama, Tatsuaki|Endo, Itaru|Nakatsura, Tetsuya
PMID: 25354479
Journal: Virchows Arch. 2015 Jan;466(1):67-76.
Title: Glypican 3 overexpression in primary and metastatic Wilms tumors.
Author: Tretiakova, Maria|Zynger, Debra L|Luan, Chunyan|Andeen, Nicole K|Finn, Laura S|Kocherginsky, Masha|Teh, Bin T|Yang, Ximing J
PMID: 25366870
Journal: Med Oncol. 2015 Jan;32(1):359.
Title: Reevaluation of glypican-3 as a prognostic marker in HCC using X-tile software.
Author: Pan, Chenwei|Wang, Xiaodong|Chen, Weilai|Tao, Chonglin|Xu, Xiaowu|Jin, Lingxiang|Chen, Yongping|Zhu, Lihe|Zhou, Lingli|Pan, Zhenzhen
PMID: 25432695
Journal: Eur J Pharmacol. 2015 Jan 5;746:353-62.
Title: Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma.
Author: Zaghloul, Randa A|El-Shishtawy, Mamdouh M|El Galil, Khaled H Abd|Ebrahim, Mohamed A|Metwaly, AbdelHamid A|Al-Gayyar, Mohammed M
PMID: 25449037
Journal: Int J Biol Markers. 2015 Feb 24;30(1):e32-42.
Title: Serological tumor markers of hepatocellular carcinoma: a meta-analysis.
Author: Hussein, Tarek D
PMID: 25450646
Journal: Biosens Bioelectron. 2015 Apr 15;66:399-404.
Title: Enzyme-free and label-free fluorescence sensor for the detection of liver cancer related short gene.
Author: Li, Xianghui|Gan, Longjie|Ou, Qishui|Zhang, Xi|Cai, Shuxian|Wu, Dongzhi|Chen, Mei|Xia, Yaokun|Chen, Jinghua|Yang, Bin
PMID: 25483916
Journal: Carcinogenesis. 2015 Feb;36(2):232-42.
Title: Expression of glypican 3 enriches hepatocellular carcinoma development-related genes and associates with carcinogenesis in cirrhotic livers.
Author: Liu, Xiyong|Wang, Sean K|Zhang, Keqiang|Zhang, Hang|Pan, Qin|Liu, Zhiwei|Pan, Hongming|Xue, Lijun|Yen, Yun|Chu, Peiguo G
PMID: 25542894
Journal: Int J Oncol. 2015 Mar;46(3):1275-85.
Title: Glypican-3 promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through ERK signaling pathway.
Author: Wu, Yongle|Liu, Hui|Weng, Honglei|Zhang, Xin|Li, Peng|Fan, Chun-Lei|Li, Bing|Dong, Pei-Ling|Li, Lei|Dooley, Steven|Ding, Hui-Guo
PMID: 25572615
Journal: Mol Med Rep. 2015 May;11(5):3361-7.
Title: Enhanced specific antitumor immunity of dendritic cells transduced with the glypican 3 gene and co-cultured with cytokine-induced killer cells against hepatocellular carcinoma cells.
Author: Wang, Yuliang|Wang, Yinlong|Mu, Hong|Liu, Tao|Chen, Xiaobo|Shen, Zhongyang
PMID: 25625609
Journal: J Biol Chem. 2015 Mar 20;290(12):7576-85.
Title: Processing by convertases is required for glypican-3-induced inhibition of Hedgehog signaling.
Author: Capurro, Mariana|Shi, Wen|Izumikawa, Tomomi|Kitagawa, Hiroshi|Filmus, Jorge
PMID: 25653284
Journal: Int J Clin Exp Pathol. 2015 Jan 1;8(1):995-9. eCollection 2015.
Title: Simultaneous double primary clear cell carcinomas of liver and kidney: a case report and review of literature.
Author: Zhang, Wei|Wang, Qiang|Jiang, Yan-Xia|Lu, Qing|Yu, Wen-Juan|Liu, Yan|Liu, Yu-Lin|Zhao, Hui|Zhuang, Jie|Li, Yu-Jun
PMID: 25755808
Journal: Int J Cancer. 2015 Oct 1;137(7):1643-51.
Title: High preoperative levels of serum glypican-3 containing N-terminal subunit are associated with poor prognosis in patients with hepatocellular carcinoma after partial hepatectomy.
Author: Haruyama, Yukihiro|Yorita, Kenji|Yamaguchi, Tetsuji|Kitajima, Sachiko|Amano, Jun|Ohtomo, Toshihiko|Ohno, Akinobu|Kondo, Kazuhiro|Kataoka, Hiroaki
PMID: 25784484
Journal: Anticancer Res. 2015 Apr;35(4):2021-8.
Title: Gene expression analysis for evaluation of potential biomarkers in hepatocellular carcinoma.
Author: Hass, Holger G|Jobst, Juergen|Scheurlen, Michael|Vogel, Ulrich|Nehls, Oliver
PMID: 25862856
Journal: World J Gastroenterol. 2015 Apr 14;21(14):4275-83.
Title: Preparation of magnetic resonance probes using one-pot method for detection of hepatocellular carcinoma.
Author: Li, You-Wei|Chen, Zheng-Guang|Zhao, Zhou-She|Li, Hong-Li|Wang, Ji-Chen|Zhang, Zong-Ming
PMID: 25892879
Journal: Diagn Pathol. 2015 Apr 21;10:34.
Title: Expression of Glypican 3 in low and high grade urothelial carcinomas.
Author: Aydin, Oguz|Yildiz, Levent|Baris, Sancar|Dundar, Cihad|Karagoz, Filiz
PMID: 25896897
Journal: Nanomedicine (Lond). 2015;10(7):1139-47.
Title: Photoimmunotherapy of hepatocellular carcinoma-targeting Glypican-3 combined with nanosized albumin-bound paclitaxel.
Author: Hanaoka, Hirofumi|Nakajima, Takahito|Sato, Kazuhide|Watanabe, Rira|Phung, Yen|Gao, Wei|Harada, Toshiko|Kim, Insook|Paik, Chang H|Choyke, Peter L|Ho, Mitchell|Kobayashi, Hisataka
PMID: 25929570
Journal: Histopathology. 2015 Dec;67(6):905-13.
Title: Quantification of glypican 3, beta-catenin and claudin-1 protein expression in hepatoblastoma and paediatric hepatocellular carcinoma by colour deconvolution.
Author: Zhou, Shengmei|Parham, David M|Yung, Evan|Pattengale, Paul|Wang, Larry
PMID: 25939253
Journal: ACS Appl Mater Interfaces. 2015 May 27;7(20):10935-43.
Title: Multifunctional biocompatible graphene oxide quantum dots decorated magnetic nanoplatform for efficient capture and two-photon imaging of rare tumor cells.
Author: Shi, Yongliang|Pramanik, Avijit|Tchounwou, Christine|Pedraza, Francisco|Crouch, Rebecca A|Chavva, Suhash Reddy|Vangara, Aruna|Sinha, Sudarson Sekhar|Jones, Stacy|Sardar, Dhiraj|Hawker, Craig|Ray, Paresh Chandra
PMID: 25939643
Journal: Mol Pharm. 2015 Jun 1;12(6):2151-7.
Title: Glypican-3 targeted human heavy chain antibody as a drug carrier for hepatocellular carcinoma therapy.
Author: Hanaoka, Hirofumi|Nagaya, Tadanobu|Sato, Kazuhide|Nakamura, Yuko|Watanabe, Rira|Harada, Toshiko|Gao, Wei|Feng, Mingqian|Phung, Yen|Kim, Insook|Paik, Chang H|Choyke, Peter L|Ho, Mitchell|Kobayashi, Hisataka
PMID: 25955255
Journal: Tumour Biol. 2015 Sep;36(10):7997-8006.
Title: Downregulation of glypican-3 expression increases migration, invasion, and tumorigenicity of human ovarian cancer cells.
Author: Liu, Ying|Zheng, Dongping|Liu, Mingming|Bai, Jiao|Zhou, Xi|Gong, Baolan|Lu, Jieyu|Zhang, Yi|Huang, Hui|Luo, Wenying|Huang, Guangrong
PMID: 25967456
Journal: Asian Pac J Cancer Prev. 2015;16(9):3595-604.
Title: Current trends and recent advances in diagnosis, therapy, and prevention of hepatocellular carcinoma.
Author: Wang, Chun-Hsiang|Wey, Keh-Cherng|Mo, Lein-Ray|Chang, Kuo-Kwan|Lin, Ruey-Chang|Kuo, Jen-Juan
PMID: 25987009
Journal: Cancer Sci. 2015 Aug;106(8):972-81.
Title: Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.
Author: Chen, Xi|Yamamoto, Masahiro|Fujii, Kiyonaga|Nagahama, Yasuharu|Ooshio, Takako|Xin, Bing|Okada, Yoko|Furukawa, Hiroyuki|Nishikawa, Yuji
PMID: 26011625
Journal: Gastroenterology. 2015 Oct;149(4):1042-52.
Title: T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice.
Author: Dargel, Christina|Bassani-Sternberg, Michal|Hasreiter, Julia|Zani, Fabio|Bockmann, Jan-Hendrik|Thiele, Frank|Bohne, Felix|Wisskirchen, Karin|Wilde, Susanne|Sprinzl, Martin F|Schendel, Dolores J|Krackhardt, Angela M|Uckert, Wolfgang|Wohlleber, Dirk|Schiema
PMID: 26052074
Journal: Asian Pac J Cancer Prev. 2015;16(11):4769-75.
Title: Roles of Combined Glypican-3 and Glutamine Synthetase in Differential Diagnosis of Hepatocellular Lesions.
Author: Wasfy, Rania Elsayed|Shams Eldeen, Aliaa Atef
PMID: 26107238
Journal: PLoS One. 2015 Sep 2;10(9):e0137664.
Title: Human Monoclonal Antibody Targeting the Heparan Sulfate Chains of Glypican-3 Inhibits HGF-Mediated Migration and Motility of Hepatocellular Carcinoma Cells.
Author: Gao, Wei|Kim, Heungnam|Ho, Mitchell
PMID: 26332121
Journal: Cancer Biomark. 2015;15(5):677-83.
Title: Significance of combined tests of serum golgi glycoprotein 73 and other biomarkers in diagnosis of small primary hepatocellular carcinoma.
Author: Zhao, Yunsheng|Wang, Meng|Cui, Chenying|Zhang, Lina|Liao, Fei|Li, Hongchen|Wu, Xia
PMID: 26406957
Journal: Eur Rev Med Pharmacol Sci. 2015 Oct;19(19):3655-73.
Title: Diagnosis accuracy of serum Glypican-3 level in patients with hepatocellular carcinoma and liver cirrhosis: a meta-analysis.
Author: Liu, J-W|Zuo, X-L|Wang, S
PMID: 26502856
Journal: J Hepatol. 2016 Jan;64(1):87-93.
Title: Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications.
Author: Sciarra, Amedeo|Di Tommaso, Luca|Nakano, Masayuki|Destro, Annarita|Torzilli, Guido|Donadon, Matteo|Maggioni, Marco|Bosari, Silvano|Bulfamante, Gaetano|Matsuda, Masanori|Fujii, Hideki|Ichikawa, Tomoaki|Morisaka, Hiroyuki|Sano, Katsuhiro|Ichikawa, Shintaro|
PMID: 26343958
Journal: Biosci Trends. 2016 May 23;10(2):85-91.
Title: Status of and prospects for cancer vaccines against hepatocellular carcinoma in clinical trials.
Author: Sun, Zhipeng|Zhu, Yubing|Xia, Jufeng|Sawakami, Tatsuo|Kokudo, Norihiro|Zhang, Nengwei
PMID: 26522694
Journal: Analyst. 2016 Jan 7;141(1):36-44.
Title: Serum protein biomarkers relevant to hepatocellular carcinoma and their detection.
Author: Waidely, Eric|Al-Yuobi, Abdul-Rahman Obaid|Bashammakh, A S|El-Shahawi, Mohammad S|Leblanc, Roger M
PMID: 26606739
Journal: Biochem Biophys Res Commun. 2016 Jan 1;469(1):138-143.
Title: Vaccination with liposome-coupled glypican-3-derived epitope peptide stimulates cytotoxic T lymphocytes and inhibits GPC3-expressing tumor growth in mice.
Author: Iwama, Tatsuaki|Uchida, Tetsuya|Sawada, Yu|Tsuchiya, Nobuhiro|Sugai, Shiori|Fujinami, Norihiro|Shimomura, Manami|Yoshikawa, Toshiaki|Zhang, Rong|Uemura, Yasushi|Nakatsura, Tetsuya
PMID: 26616051
Journal: Small. 2016 Jan 27;12(4):477-87.
Title: Iron-Oxide-Based Nanovector for Tumor Targeted siRNA Delivery in an Orthotopic Hepatocellular Carcinoma Xenograft Mouse Model.
Author: Wang, Kui|Kievit, Forrest M|Sham, Jonathan G|Jeon, Mike|Stephen, Zachary R|Bakthavatsalam, Arvind|Park, James O|Zhang, Miqin
PMID: 26641029
Journal: World J Gastroenterol. 2016 Jan 7;22(1):275-83.
Title: Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinoma.
Author: Haruyama, Yukihiro|Kataoka, Hiroaki
PMID: 26755876
Journal: APMIS. 2016 Mar;124(3):208-15.
Title: Expression profile and prognostic value of glypican-3 in post-operative South Korean hepatocellular carcinoma patients.
Author: Jeon, Yejoo|Kim, Haeryoung|Jang, Eun Sun|Hong, Sukho|Kim, Jin Wook|Yoon, Yoo-Seok|Cho, Jai Young|Han, Ho-Seong|Jeong, Sook-Hyang
PMID: 26764243
Journal: Bioconjug Chem. 2016 Mar 16;27(3):831-9.
Title: Novel Glypican-3-Binding Peptide for in Vivo Hepatocellular Carcinoma Fluorescent Imaging.
Author: Zhu, Dongling|Qin, Yushuang|Wang, Jingjing|Zhang, Liwen|Zou, Sijuan|Zhu, Xiaohua|Zhu, Lei
PMID: 26850086
Journal: Oncoimmunology. 2015 Aug 31;5(1):e1062209.
Title: Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response.
Author: Sayem, Mohammad A|Tomita, Yusuke|Yuno, Akira|Hirayama, Masatoshi|Irie, Atsushi|Tsukamoto, Hirotake|Senju, Satoru|Yuba, Eiji|Yoshikawa, Toshiaki|Kono, Kenji|Nakatsura, Tetsuya|Nishimura, Yasuharu
PMID: 26942076
Journal: PLoS One. 2016 Mar 15;11(3):e0151501.
Title: CK19 and Glypican 3 Expression Profiling in the Prognostic Indication for Patients with HCC after Surgical Resection.
Author: Feng, Jiliang|Zhu, Ruidong|Chang, Chun|Yu, Lu|Cao, Fang|Zhu, Guohua|Chen, Feng|Xia, Hui|Lv, Fudong|Zhang, Shijie|Sun, Lin
PMID: 26977595
Journal: PLoS One. 2016 Apr 13;11(4):e0153613.
Title: Modeling of Hepatocytes Proliferation Isolated from Proximal and Distal Zones from Human Hepatocellular Carcinoma Lesion.
Author: Montalbano, Mauro|Curcuru, Giuseppe|Shirafkan, Ali|Vento, Renza|Rastellini, Cristiana|Cicalese, Luca
PMID: 27074018
Journal: J Hepatol. 2016 Aug;65(2):289-95.
Title: Randomized phase II placebo controlled study of codrituzumab in previously treated patients with advanced hepatocellular carcinoma.
Author: Abou-Alfa, Ghassan K|Puig, Oscar|Daniele, Bruno|Kudo, Masatoshi|Merle, Philippe|Park, Joong-Won|Ross, Paul|Peron, Jean-Marie|Ebert, Oliver|Chan, Stephen|Poon, Tung Ping|Colombo, Massimo|Okusaka, Takuji|Ryoo, Baek-Yeol|Minguez, Beatriz|Tanaka, Takayoshi|Oh
PMID: 27085251
Journal: Exp Cell Res. 2016 May 1;343(2):135-147.
Title: MicroRNA-133b inhibits hepatocellular carcinoma cell progression by targeting Sirt1.
Author: Tian, Zhijie|Jiang, Hequn|Liu, Ying|Huang, Yong|Xiong, Xin|Wu, Hongwei|Dai, Xiaozhen
PMID: 27090017
Journal: Int J Immunogenet. 2016 Jun;43(3):166-70.
Title: Prediction and preliminary screening of HLA-A*0201-restricted epitope peptides of human GPC3.
Author: Hu, P|Wei, Z|Li, R|Wu, D|Meng, Z
PMID: 27102087
Journal: Tumour Biol. 2016 Sep;37(9):12113-12121.
Title: Targeted nanobubbles in low-frequency ultrasound-mediated gene transfection and growth inhibition of hepatocellular carcinoma cells.
Author: Wu, Bolin|Qiao, Qiang|Han, Xue|Jing, Hui|Zhang, Hao|Liang, Hongjian|Cheng, Wen
PMID: 27216880
Journal: Biosens Bioelectron. 2016 Nov 15;85:633-640.
Title: Biofunctionalized magnetic nanospheres-based cell sorting strategy for efficient isolation, detection and subtype analyses of heterogeneous circulating hepatocellular carcinoma cells.
Author: Chen, Lan|Wu, Ling-Ling|Zhang, Zhi-Ling|Hu, Jiao|Tang, Man|Qi, Chu-Bo|Li, Na|Pang, Dai-Wen
PMID: 27240010
Journal: Endocr Pathol. 2016 Sep;27(3):253-8.
Title: Liver Metastases of Neuroendocrine Tumors Rarely Show Overlapping Immunoprofile with Hepatocellular Carcinomas.
Author: Jin, Ming|Zhou, Xiaoping|Yearsley, Martha|Frankel, Wendy L
PMID: 27300354
Journal: Tumour Biol. 2016 Sep;37(9):12571-12577.
Title: GPC-HCC model: a combination of glybican-3 with other routine parameters improves the diagnostic efficacy in hepatocellular carcinoma.
Author: Attallah, Abdelfattah M|El-Far, Mohamed|Omran, Mohamed M|Abdelrazek, Mohamed A|Attallah, Ahmed A|Saeed, Aya M|Farid, Khaled
PMID: 27380057
Journal: Oncoimmunology. 2016 Jan 19;5(5):e1129483.
Title: Phase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients.
Author: Sawada, Yu|Yoshikawa, Toshiaki|Ofuji, Kazuya|Yoshimura, Mayuko|Tsuchiya, Nobuhiro|Takahashi, Mari|Nobuoka, Daisuke|Gotohda, Naoto|Takahashi, Shinichiro|Kato, Yuichiro|Konishi, Masaru|Kinoshita, Taira|Ikeda, Masafumi|Nakachi, Kohei|Yamazaki, Naoya|Mizuno,
PMID: 27467945
Journal: Hepatobiliary Pancreat Dis Int. 2016 Aug;15(4):371-7.
Title: Predictive value of tumor markers in patients with recurrent hepatocellular carcinoma in different vascular invasion pattern.
Author: Gao, Feng|Zhu, Heng-Kai|Zhu, Yang-Bo|Shan, Qiao-Nan|Ling, Qi|Wei, Xu-Yong|Xie, Hai-Yang|Zhou, Lin|Xu, Xiao|Zheng, Shu-Sen
PMID: 27498576
Journal: Chin J Cancer. 2016 Aug 24;35(1):82.
Title: Combined hepatocellular and cholangiocarcinoma originating from the same clone: a pathomolecular evidence-based study.
Author: Zhao, Qian|Yu, Wen-Long|Lu, Xin-Yuan|Dong, Hui|Gu, Yi-Jin|Sheng, Xia|Cong, Wen-Ming|Wu, Meng-Chao
PMID: 27552844
Journal: J Gastrointest Oncol. 2016 Aug;7(4):570-9.
Title: A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
Author: Mok, Shaffer R S|Mohan, Sachin|Grewal, Navjot|Elfant, Adam B|Judge, Thomas A
PMID: 27563447
Journal: FEBS J. 2016 Oct;283(20):3739-3754.
Title: Long noncoding RNA glypican 3 (GPC3) antisense transcript 1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3.
Author: Zhu, Xiao-Ting|Yuan, Ji-Hang|Zhu, Teng-Teng|Li, Yang-Yang|Cheng, Xiao-Yang
PMID: 27573079
Journal: Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12372-5.
Title: Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution.
Author: Zhang, Liqin|Yang, Zunyi|Le Trinh, Thu|Teng, I-Ting|Wang, Sai|Bradley, Kevin M|Hoshika, Shuichi|Wu, Qunfeng|Cansiz, Sena|Rowold, Diane J|McLendon, Christopher|Kim, Myong-Sang|Wu, Yuan|Cui, Cheng|Liu, Yuan|Hou, Weijia|Stewart, Kimberly|Wan, Shuo|Liu, Chen|
PMID: 27601357
Journal: Asian Pac J Trop Med. 2016 Sep;9(9):898-902.
Title: Effect of co-transfection of miR-520c-3p and miR-132 on proliferation and apoptosis of hepatocellular carcinoma Huh7.
Author: Lei, Chang-Jiang|Yao, Chun|Li, De-Ke|Long, Zhi-Xiong|Li, Yuan|Tao, Dan|Liou, Yan-Ping|Zhang, Jiang-Zhou|Liu, Ning
PMID: 27633306
Journal: Oncotarget. 2016 Nov 8;7(45):73754-73768.
Title: Bone morphogenetic protein-9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population.
Author: Jung, Jae Woo|Yoon, So-Mi|Kim, Subin|Jeon, Yun-Hui|Yoon, Byung-Hak|Yang, Su-Geun|Kim, Min Kyoung|Choe, Senyon|Kuo, Mario Meng-Chiang
PMID: 27650540
Journal: Oncotarget. 2016 Oct 25;7(43):69916-69926.
Title: Evaluating clinical and prognostic implications of Glypican-3 in hepatocellular carcinoma.
Author: Kaseb, Ahmed Omar|Hassan, Manal|Lacin, Sahin|Abdel-Wahab, Reham|Amin, Hesham M|Shalaby, Ahmed|Wolff, Robert A|Yao, James|Rashid, Asif|Vennapusa, Bharathi|Feng, Janine|Ohtomo, Toshihiko
PMID: 27655712
Journal: Sci Rep. 2016 Sep 26;6:33878.
Title: Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.
Author: Zhang, Yi-Fan|Ho, Mitchell
PMID: 27667400
Journal: Toxins (Basel). 2016 Sep 22;8(10). pii: toxins8100274.
Title: Glypican-3 Targeting Immunotoxins for the Treatment of Liver Cancer.
Author: Fleming, Bryan D|Ho, Mitchell
PMID: 27669301
Journal: Anal Chim Acta. 2016 Oct 19;941:87-93.
Title: Peroxidase-like catalytic activity of copper ions and its application for highly sensitive detection of glypican-3.
Author: Zheng, Aixian|Zhang, Xiaolong|Gao, Ju|Liu, Xiaolong|Liu, Jingfeng
PMID: 27692382
Journal: Clin Mol Hepatol. 2016 Sep;22(3):359-365.
Title: Glypican-3 level assessed by the enzyme-linked immunosorbent assay is inferior to alpha-fetoprotein level for hepatocellular carcinoma diagnosis.
Author: Jeon, Yejoo|Jang, Eun Sun|Choi, Yun Suk|Kim, Jin-Wook|Jeong, Sook-Hyang
PMID: 27729630
Journal: J Hepatocell Carcinoma. 2016 Nov 8;3:63-67.
Title: GPC-3 in hepatocellular carcinoma: current perspectives.
Author: Wu, Yongle|Liu, Hui|Ding, Huiguo
PMID: 27878117
Journal: Front Immunol. 2017 Jan 11;7:690.
Title: Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma.
Author: Jiang, Zhiwu|Jiang, Xiaofeng|Chen, Suimin|Lai, Yunxin|Wei, Xinru|Li, Baiheng|Lin, Simiao|Wang, Suna|Wu, Qiting|Liang, Qiubin|Liu, Qifa|Peng, Muyun|Yu, Fenglei|Weng, Jianyu|Du, Xin|Pei, Duanqing|Liu, Pentao|Yao, Yao|Xue, Ping|Li, Peng
PMID: 28123387
Journal: Pathol Oncol Res. 2017 Jan;23(1):33-39.
Title: Markers of Hippo-Pathway Activity in Tumor Forming Liver Lesions.
Author: Reis, Henning|Bertram, Stefanie|Pott, Leona|Canbay, Ali|Gallinat, Anja|Baba, Hideo Andreas
PMID: 27276915
Journal: Oncotarget. 2017 May 16;8(20):32450-32460.
Title: Construction of an immunotoxin, HN3-mPE24, targeting glypican-3 for liver cancer therapy.
Author: Wang, Chunguang|Gao, Wei|Feng, Mingqian|Pastan, Ira|Ho, Mitchell
PMID: 27419635
Journal: Hum Gene Ther. 2017 May;28(5):437-448.
Title: Redirecting T Cells to Glypican-3 with 4-1BB Zeta Chimeric Antigen Receptors Results in Th1 Polarization and Potent Antitumor Activity.
Author: Li, Wenpeng|Guo, Linjie|Rathi, Purva|Marinova, Ekaterina|Gao, Xiuhua|Wu, Meng-Feng|Liu, Hao|Dotti, Gianpietro|Gottschalk, Stephen|Metelitsa, Leonid S|Heczey, Andras
PMID: 27530312
Journal: Macromol Biosci. 2017 Apr;17(4).
Title: Identification of a Glypican-3-Binding Peptide for In Vivo Non-Invasive Human Hepatocellular Carcinoma Detection.
Author: Qin, Zainen|Wang, Jingjing|Wang, Ye|Wang, Guohao|Wang, Xiangyu|Zhou, Zhiyang|Liu, Gang|Gao, Shi|Zhu, Lei
PMID: 27862961
Journal: Oncotarget. 2017 Jun 6;8(23):37835-37844.
Title: Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma.
Author: Ofuji, Kazuya|Saito, Keigo|Suzuki, Shiro|Shimomura, Manami|Shirakawa, Hirofumi|Nobuoka, Daisuke|Sawada, Yu|Yoshimura, Mayuko|Tsuchiya, Nobuhiro|Takahashi, Mari|Yoshikawa, Toshiaki|Tada, Yoshitaka|Konishi, Masaru|Takahashi, Shinichiro|Gotohda, Naoto|Nakamo
PMID: 28035063
Journal: Cancer Immunol Immunother. 2017 Apr;66(4):475-489.
Title: Development of T cells carrying two complementary chimeric antigen receptors against glypican-3 and asialoglycoprotein receptor 1 for the treatment of hepatocellular carcinoma.
Author: Chen, Cheng|Li, Kesang|Jiang, Hua|Song, Fei|Gao, Huiping|Pan, Xiaorong|Shi, Bizhi|Bi, Yanyu|Wang, Huamao|Wang, Hongyang|Li, Zonghai
PMID: 28035433
Journal: J Gastroenterol Hepatol. 2017 Aug;32(8):1503-1511.
Title: The significance of glypican-3 expression profiling in the tumor cellular origin theoretical system for hepatocellular carcinoma progression.
Author: Xue, Ran|Feng, Jiliang|Meng, Qinghua|Lv, Fudong|Zhu, Yueke|Yu, Hongwei|Zhang, Shijie|Song, Chenzhao|Sun, Lin|Yue, Zhujun|Feng, Shuai|Che, Ruiwen|Xiang, Qian|Jing, Xiaodan
PMID: 28087980
Journal: Oncol Rep. 2017 Mar;37(3):1291-1300.
Title: Biology and function of glypican-3 as a candidate for early cancerous transformation of hepatocytes in hepatocellular carcinoma (Review).
Author: Montalbano, Mauro|Georgiadis, Jeremias|Masterson, Ashlyn L|McGuire, Joshua T|Prajapati, Janika|Shirafkan, Ali|Rastellini, Cristiana|Cicalese, Luca
PMID: 28098909
Journal: Cancer Chemother Pharmacol. 2017 Feb;79(2):421-429.
Title: Phase Ib study of codrituzumab in combination with sorafenib in patients with non-curable advanced hepatocellular carcinoma (HCC).
Author: Abou-Alfa, Ghassan K|Yen, Chia-Jui|Hsu, Chih-Hung|O'Donoghue, Joseph|Beylergil, Volkan|Ruan, Shutian|Pandit-Taskar, Neeta|Gansukh, Bolorsukh|Lyashchenko, Serge K|Ma, Jennifer|Wan, Peter|Shao, Yu-Yun|Lin, Zhong-Zhe|Frenette, Catherine|O'Neil, Bert|Schwartz
PMID: 28120036
Journal: Genet Mol Res. 2017 Feb 8;16(1). pii: gmr-16-01-gmr.16018947.
Title: Nested polymerase chain reaction technique for the detection of Gpc3 and Afp mRNA in liver cancer micrometastases.
Author: Luo, J|Yang, K|Wen, Y G
PMID: 28198497
Journal: Med Sci Monit. 2017 Feb 16;23:850-855.
Title: Significance of Glypican-3 (GPC3) Expression in Hepatocellular Cancer Diagnosis.
Author: Sun, Bin|Huang, Zhi|Wang, Bi|Yu, Yanglong|Lin, Shihai|Luo, Lei|Wang, Yuzhu|Huang, Zheng
PMID: 28207681
Journal: Sci Rep. 2017 Mar 9;7:44036.
Title: Simple Risk Score for Prediction of Early Recurrence of Hepatocellular Carcinoma within the Milan Criteria after Orthotopic Liver Transplantation.
Author: Feng, Jiliang|Wu, Jushan|Zhu, Ruidong|Feng, Dezhao|Yu, Lu|Zhang, Yan|Bu, Dayu|Li, Chenlei|Zhou, Yuyan|Si, Lianghao|Liu, Yuhan|Liang, Ziwei|Xu, Jianing|Wu, Tianjun
PMID: 28276470
Journal: J Fluoresc. 2017 Jul;27(4):1479-1485.
Title: Development of a Time-Resolved Fluorescence Immunoassay for the Diagnosis of Hepatocellular Carcinoma Based on the Detection of Glypican-3.
Author: Chen, Juan-Juan|Xie, Chun-Mei|Wang, Cong-Rong|Wan, Yong|Dong, Zhi-Ning|Li, Ming|Xu, Wei-Wen
PMID: 28429175
Journal: Oncotarget. 2017 Apr 11;8(15):24785-24796.
Title: Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector.
Author: Liu, Quan|Yang, Yijun|Tan, Xuefang|Tao, Zhu|Adah, Dickson|Yu, Songlin|Lu, Junnan|Zhao, Siting|Qin, Limei|Qin, Li|Chen, Xiaoping
PMID: 28445973
Journal: Discov Med. 2017 Mar;23(126):163-168.
Title: Diagnosis of AFP-negative early-stage hepatocellular carcinoma using Fuc-PON1.
Author: Shu, Hong|Li, Wei|Shang, Shuxin|Qin, Xue|Zhang, Shu|Liu, Yinkun
PMID: 28472609
Journal: Oncotarget. 2017 Jun 20;8(25):41211-41226.
Title: New tumor suppressor microRNAs target glypican-3 in human liver cancer.
Author: Cartier, Flora|Indersie, Emilie|Lesjean, Sarah|Charpentier, Justine|Hooks, Katarzyna B|Ghousein, Amani|Desplat, Angelique|Dugot-Senant, Nathalie|Trezeguet, Veronique|Sagliocco, Francis|Hagedorn, Martin|Grosset, Christophe F
PMID: 28476031
Journal: Clin Transl Med. 2017 Dec;6(1):18.
Title: Can glypican-3 be a disease-specific biomarker?
Author: Chen, Chaolei|Huang, Xiaomin|Ying, Zhaojian|Wu, Dengmin|Yu, Yani|Wang, Xiangdong|Chen, Chengshui
PMID: 28510121
Journal: Asian Pac J Cancer Prev. 2017 Apr 1;18(4):863-872.
Title: Hepatocellular Carcinoma: a Comprehensive Review of Biomarkers, Clinical Aspects, and Therapy
Author: Tunissiolli, Nathalia Martines|Castanhole-Nunes, Marcia Maria Urbanin|Biselli-Chicote, Patricia Matos|Pavarino, Erika Cristina|da Silva, Renato Ferreira|da Silva, Rita de Cassia Martins Alves|Goloni-Bertollo, Eny Maria
PMID: 28545181
Journal: Zhonghua Gan Zang Bing Za Zhi. 2017 Jun 20;25(6):435-439.
Title: [A bioinformatics analysis of differentially expressed genes associated with liver cancer].
Author: Bai, W X|Gao, J|Qian, C|Zhang, X Q
PMID: 28763861
Journal: Sci China Life Sci. 2017 Nov;60(11):1203-1213.
Title: MXR7 facilitates liver cancer metastasis via epithelial-mesenchymal transition.
Author: Lv, Guishuai|Tan, Yexiong|Lv, Hongwei|Fang, Tian|Wang, Changzheng|Li, Ting|Yu, Yanting|Hu, Congli|Wen, Wen|Wang, Hongyang|Yang, Wen
PMID: 28812296
Journal: Sci Rep. 2017 Aug 29;7(1):9608.
Title: Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3.
Author: Xie, Chunmei|Tiede, Christian|Zhang, Xuanyi|Wang, Congrong|Li, Zhixiong|Xu, Xiao|McPherson, Michael J|Tomlinson, Darren C|Xu, Weiwen
PMID: 28852111
Journal: Mol Ther Oncolytics. 2017 Jul 28;6:69-79.
Title: T Cell-Activating Mesenchymal Stem Cells as a Biotherapeutic for HCC.
Author: Szoor, Arpad|Vaidya, Abishek|Velasquez, Mireya Paulina|Mei, Zhuyong|Galvan, Daniel L|Torres, David|Gee, Adrian|Heczey, Andras|Gottschalk, Stephen
PMID: 28856237
Journal: Mol Ther. 2017 Oct 4;25(10):2299-2308.
Title: A Novel Vaccine Targeting Glypican-3 as a Treatment for Hepatocellular Carcinoma.
Author: Wu, Qunfeng|Pi, Liya|Le Trinh, Thu|Zuo, Chaohui|Xia, Man|Jiao, Yu|Hou, Zhouhua|Jo, Sung|Puszyk, William|Pham, Kien|Nelson, David R|Robertson, Keith|Ostrov, David|Rameshwar, Pranela|Xia, Chang Qing|Liu, Chen
PMID: 28865999
Journal: Pathol Res Pract. 2017 Sep;213(9):1037-1042.
Title: Correlation between HBV protein preS2 and tumor markers of hepatocellular carcinoma.
Author: Luan, Fang|Liu, Bin|Zhang, Junguo|Cheng, Shiqing|Zhang, Bingchang|Wang, Yong
PMID: 28869105
Journal: Oncotarget. 2017 May 16;8(32):52866-52876.
Title: Treatment of hepatocellular carcinoma with a GPC3-targeted bispecific T cell engager.
Author: Bi, Yanyu|Jiang, Hua|Wang, Peng|Song, Bo|Wang, Huamao|Kong, Xianming|Li, Zonghai
PMID: 28881778
Journal: Cancer Genet. 2017 Oct;216-217:37-51.
Title: Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets.
Author: Agarwal, Rahul|Narayan, Jitendra|Bhattacharyya, Amitava|Saraswat, Mayank|Tomar, Anil Kumar
PMID: 29025594
Journal: Biomater Sci. 2017 Nov 21;5(12):2468-2479.
Title: Codelivery of sorafenib and GPC3 siRNA with PEI-modified liposomes for hepatoma therapy.
Author: Sun, Weitong|Wang, Yong|Cai, Mingyue|Lin, Liteng|Chen, Xiaoyan|Cao, Zhong|Zhu, Kangshun|Shuai, Xintao
PMID: 29106433
Journal: Oncotarget. 2017 Jul 6;8(46):80429-80442.
Title: Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10.
Author: Cheng, Wei|Huang, Po-Chun|Chao, Hsiao-Mei|Jeng, Yung-Ming|Hsu, Hey-Chi|Pan, Hung-Wei|Hwu, Wuh-Liang|Lee, Yu-May
PMID: 29113314
Journal: Oncoimmunology. 2017 Jul 11;6(10):e1346764.
Title: Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma.
Author: Tsuchiya, Nobuhiro|Yoshikawa, Toshiaki|Fujinami, Norihiro|Saito, Keigo|Mizuno, Shoichi|Sawada, Yu|Endo, Itaru|Nakatsura, Tetsuya
PMID: 29123959
Journal: Proteomes. 2017 Nov 23;5(4). pii: proteomes5040033.
Title: Variety and Dynamics of Proteoforms in the Human Proteome: Aspects of Markers for Hepatocellular Carcinoma.
Author: Naryzhny, Stanislav|Zgoda, Victor|Kopylov, Artur|Petrenko, Elena|Kleist, Olga|Archakov, capital A, Cyrilliclexander
PMID: 29168748
Journal: Asian Pac J Trop Med. 2017 Nov;10(11):1084-1089.
Title: Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in vitro.
Author: Zeng, Jiang-Zheng|Liu, Yu|Huang, Fen|He, Zhi-Hui|Sun, Huamao|Lu, Yan-Da|Lei, Jun-Hua|Luo, Rong-Cheng
PMID: 29203107
Journal: Clin Lab. 2017 Nov 1;63(11):1903-1909.
Title: The Value of GPC3 and GP73 in Clinical Diagnosis of Hepatocellular Carcinoma.
Author: Jing, Ji-Sheng|Ye, Wei|Jiang, Ying-Kui|Ma, Jie|Zhu, Meng-Qi|Ma, Jiu-Ming|Zhou, Hua|Yu, La-Qing|Yang, Yong-Feng|Wang, Shun-Cai
PMID: 29226636
Journal: Sci Rep. 2017 Dec 19;7(1):17751.
Title: A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma.
Author: Woodfield, Sarah E|Shi, Yan|Patel, Roma H|Jin, Jingling|Major, Angela|Sarabia, Stephen F|Starosolski, Zbigniew|Zorman, Barry|Gupta, Siddharth S|Chen, Zhenghu|Ibarra, Aryana M|Bissig, Karl-Dimiter|Ghaghada, Ketan B|Sumazin, Pavel|Lopez-Terrada, Dolores|Vas
PMID: 29259231
Journal: Egypt J Immunol. 2017 Jun;24(2):187-200.
Title: Glypican-3 and Melanoma Antigen Genes 1 and 3 as Tumor Markers for Hepatocellular Carcinoma.
Author: El-Wahab, Nadia M|Rashed, Hebat-Allah G|El-Sherif, Wafaa T|Sayed, Sohair K|Abd-Elmalek, Mohamed O|Refaiy, Abeer|Fakhry, Hussein|Mokhtar, Abeer A
PMID: 29708315
Journal: Med Res Rev. 2018 Mar;38(2):741-767.
Title: Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment.
Author: Zhou, Fubo|Shang, Wenting|Yu, Xiaoling|Tian, Jie
PMID: 28621802
Journal: Histopathology. 2018 Feb;72(3):414-422.
Title: From large to small: the immunohistochemical panel in the diagnosis of early hepatocellular carcinoma.
Author: Vasuri, Francesco|Malvi, Deborah|Bonora, Sonia|Fittipaldi, Silvia|Renzulli, Matteo|Tovoli, Francesco|Golfieri, Rita|Bolondi, Luigi|D'Errico, Antonia
PMID: 28881044
Journal: Amino Acids. 2018 Feb;50(2):309-320.
Title: Imaging the expression of glypican-3 in hepatocellular carcinoma by PET.
Author: Wang, Zhen|Han, Yan-Jiang|Huang, Shun|Wang, Meng|Zhou, Wen-Lan|Li, Hong-Sheng|Wang, Quan-Shi|Wu, Hu-Bing
PMID: 29204748
Journal: Cell Oncol (Dordr). 2018 Apr;41(2):169-184.
Title: Role of Glypican-3 in the growth, migration and invasion of primary hepatocytes isolated from patients with hepatocellular carcinoma.
Author: Montalbano, Mauro|Rastellini, Cristiana|McGuire, Joshua T|Prajapati, Janika|Shirafkan, Ali|Vento, Renza|Cicalese, Luca
PMID: 29204978
Journal: Gut Liver. 2018 May 15;12(3):306-315.
Title: Subclassification and Detection of New Markers for the Discrimination of Primary Liver Tumors by Gene Expression Analysis Using Oligonucleotide Arrays.
Author: Hass, Holger G|Vogel, Ulrich|Scheurlen, Michael|Jobst, Jurgen
PMID: 29271183
Journal: Biochemistry. 2018 Feb 20;57(7):1201-1211.
Title: Role of Glycanation and Convertase Maturation of Soluble Glypican-3 in Inhibiting Proliferation of Hepatocellular Carcinoma Cells.
Author: Saad, Ahmad|Liet, Benjamin|Joucla, Gilles|Santarelli, Xavier|Charpentier, Justine|Claverol, Stephane|Grosset, Christophe F|Trezeguet, Veronique
PMID: 29345911
Journal: Medicine (Baltimore). 2018 Jan;97(4):e9702.
Title: Prognostic significance of glypican-3 expression in hepatocellular carcinoma: A meta-analysis.
Author: Liu, Hong|Yang, Chunmei|Lu, Wenzhu|Zeng, Yong
PMID: 29369198
Journal: Onco Targets Ther. 2018 Jan 4;11:193-200.
Title: Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/beta-catenin signaling.
Author: Hu, Pei|Cheng, Bin|He, Yulin|Wei, Zhiqiang|Wu, Dongfang|Meng, Zhongji
PMID: 29379301
Journal: Br J Clin Pharmacol. 2018 May;84(5):944-951.
Title: Time-to-event modelling of effect of codrituzumab on overall survival in patients with hepatocellular carcinoma.
Author: Nakamura, Mikiko|Xu, Chao|Diack, Cheikh|Ohishi, Norihisa|Lee, Ruey-Min|Iida, Satofumi|Kawanishi, Takehiko|Ohtomo, Toshihiko|Abou-Alfa, Ghassan K|Chen, Ya-Chi
PMID: 29381229
Journal: World J Gastroenterol. 2018 Jan 21;24(3):371-378.
Title: Multi-parameter gene expression profiling of peripheral blood for early detection of hepatocellular carcinoma.
Author: Xie, Hui|Xue, Yao-Qin|Liu, Peng|Zhang, Peng-Jun|Tian, Sheng-Tao|Yang, Zhao|Guo, Zhi|Wang, Hua-Ming
PMID: 29391759
Journal: BMB Rep. 2018 Feb;51(2):57-58.
Title: SF3B4 as an early-stage diagnostic marker and driver of hepatocellular carcinoma.
Author: Shen, Qingyu|Nam, Suk Woo
PMID: 29397868
Journal: World J Gastroenterol. 2018 Jan 28;24(4):494-503.
Title: Low glucose metabolism in hepatocellular carcinoma with GPC3 expression.
Author: Li, You-Cai|Yang, Chuan-Sheng|Zhou, Wen-Lan|Li, Hong-Sheng|Han, Yan-Jiang|Wang, Quan-Shi|Wu, Hu-Bing
PMID: 29398870
Journal: Chemistry. 2018 May 11;24(27):7060-7067.
Title: Dual-Selective and Dual-Enhanced SERS Nanoprobes Strategy for Circulating Hepatocellular Carcinoma Cells Detection.
Author: Pang, Yuanfeng|Wang, Chongwen|Xiao, Rui|Sun, Zhiwei
PMID: 29521467
Journal: Oncotarget. 2018 Jan 2;9(12):10436-10444.
Title: Combining expression of GPC3 in tumors and CD16 on NK cells from peripheral blood to identify patients responding to codrituzumab.
Author: Chen, Gong|Chen, Ya-Chi|Reis, Bernhard|Belousov, Anton|Jukofsky, Lori|Rossin, Christine|Muehlig, Axel|Xu, Chao|Essioux, Laurent|Ohtomo, Toshihiko|Di Laurenzio, Laura|Puig, Oscar|Lee, Ray
PMID: 29535817
Journal: Prep Biochem Biotechnol. 2018 May 28;48(5):435-445.
Title: Polyclonal antibody production against rGPC3 and their application in diagnosis of hepatocellular carcinoma.
Author: Wang, Shenghao|Kalim, Muhammad|Liang, Keying|Zhan, Jinbiao
PMID: 29561231
Journal: Gene Ther. 2018 Apr;25(2):115-128.
Title: Evaluation of the Glypican 3 promoter for transcriptional targeting of hepatocellular carcinoma.
Author: Dhungel, Bijay|Andrzejewski, Slawomir|Jayachandran, Aparna|Shrestha, Ritu|Ramlogan-Steel, Charmaine A|Layton, Christopher J|Steel, Jason C
PMID: 29563582
Journal: Eur J Histochem. 2018 Jan 29;62(1):2859.
Title: Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity.
Author: Moudi, Bita|Heidari, Zahra|Mahmoudzadeh-Sagheb, Hamidreza|Alavian, Seyed-Moayed|Lankarani, Kamran B|Farrokh, Parisa|Randel Nyengaard, Jens
PMID: 29569872
Journal: J Gastrointest Cancer. 2018 Apr 6. pii: 10.1007/s12029-018-0095-2.
Title: Significance of Glypican-3 in Early Detection of Hepatocellular Carcinoma in Cirrhotic Patients.
Author: Tahon, Ahmed M|El-Ghanam, Magdy Z|Zaky, Samy|Emran, Tarek Mostafa|Bersy, Ali M|El-Raey, Fathiya|A Z, Elsayed|El Kharsawy, Amr M|Johar, Dina
PMID: 29623600
Journal: Quant Imaging Med Surg. 2018 Mar;8(2):151-160.
Title: In vivo fluorescence imaging of hepatocellular carcinoma using a novel GPC3-specific aptamer probe.
Author: Zhao, Menglong|Dong, Lili|Liu, Zhuang|Yang, Shuohui|Wu, Weizhong|Lin, Jiang
PMID: 29675356
Journal: Histopathology. 2018 Oct;73(4):601-611.
Title: Phenotypic and molecular changes in nodule-in-nodule hepatocellular carcinoma with pathogenetic implications.
Author: Rudini, Noemi|Novello, Chiara|Destro, Annarita|Riboldi, Elena|Donadon, Matteo|Vigano, Luca|Morenghi, Emanuela|Roncalli, Massimo|Di Tommaso, Luca
PMID: 29791027
Journal: PLoS One. 2018 Jun 7;13(6):e0198552.
Title: Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma.
Author: Wang, Xinmei|Kwak, Kwang Joo|Yang, Zhaogang|Zhang, Aili|Zhang, Xiaoli|Sullivan, Rachael|Lin, Dan|Lee, Robert L|Castro, Carlos|Ghoshal, Kalpana|Schmidt, Carl|Lee, L James
PMID: 29879168
Journal: Medicine (Baltimore). 2018 Jun;97(24):e11130.
Title: Overexpression of glypican-3 is a predictor of poor prognosis in hepatocellular carcinoma: An updated meta-analysis.
Author: Zhang, Jian|Zhang, Manka|Ma, Huimin|Song, Xincheng|He, Lingling|Ye, Xiaohui|Li, Xin
PMID: 29901640
Journal: Drug Deliv. 2018 Nov;25(1):1484-1494.
Title: Anti-GPC3 antibody-modified sorafenib-loaded nanoparticles significantly inhibited HepG2 hepatocellular carcinoma.
Author: Tang, Xiaolong|Chen, Longzhou|Li, Amin|Cai, Shiyu|Zhang, Yinci|Liu, Xueke|Jiang, Zhenyou|Liu, Xinkuang|Liang, Yong|Ma, Dong
PMID: 29916268
Journal: Am J Pathol. 2018 Sep;188(9):1973-1981.
Title: Glypican 3 Overexpression across a Broad Spectrum of Tumor Types Discovered with Functional Genomic mRNA Profiling of a Large Cancer Database.
Author: Moek, Kirsten L|Fehrmann, Rudolf S N|van der Vegt, Bert|de Vries, Elisabeth G E|de Groot, Derk J A
PMID: 29935166
Journal: Oncol Lett. 2018 Jul;16(1):970-976.
Title: Elevated GPC3 level promotes cell proliferation in liver cancer.
Author: Wang, Shanshan|Chen, Ning|Chen, Yuhan|Sun, Lin|Li, Li|Liu, Hui
PMID: 29963171
Journal: Dig Liver Dis. 2018 Jun 21. pii: S1590-8658(18)30799-0.
Title: Both glypican-3/Wnt/beta-catenin signaling pathway and autophagy contributed to the inhibitory effect of curcumin on hepatocellular carcinoma.
Author: Hu, Pei|Ke, Changzheng|Guo, Xingrong|Ren, Pan|Tong, Yaoyao|Luo, Sen|He, Yulin|Wei, Zhiqiang|Cheng, Bin|Li, Ruiming|Luo, Jie|Meng, Zhongji
PMID: 30001951
Journal: Am J Transl Res. 2018 Jun 15;10(6):1736-1749. eCollection 2018.
Title: Immunization with glypican-3 nanovaccine containing TLR7 agonist prevents the development of carcinogen-induced precancerous hepatic lesions to cancer in a murine model.
Author: Chen, Kun|Wu, Zhiyuan|Zang, Mengya|Wang, Ce|Wang, Yanmei|Wang, Dongmei|Ma, Yifan|Qu, Chunfeng
PMID: 30018715
Journal: Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:395-403.
Title: Enhanced delivery of sorafenib with anti-GPC3 antibody-conjugated TPGS-b-PCL/Pluronic P123 polymeric nanoparticles for targeted therapy of hepatocellular carcinoma.
Author: Gan, Huaiyong|Chen, Longzhou|Sui, Xuemei|Wu, Binquan|Zou, Shoupin|Li, Amin|Zhang, Yinci|Liu, Xueke|Wang, Danli|Cai, Shuyu|Liu, Xinkuang|Liang, Yong|Tang, Xiaolong
PMID: 30033270
Journal: J Vis Exp. 2018 Jul 12;(137).
Title: A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity.
Author: Wang, Yanlan|Liu, Jiayu|Pan, Haitao|Xing, Jieyu|Wu, Xiaoqiong|Li, Qing|Wang, Zhong
PMID: 30059039
Journal: Cancer Immunol Immunother. 2018 Aug 4. pii: 10.1007/s00262-018-2221-1.
Title: Increased antitumor activities of glypican-3-specific chimeric antigen receptor-modified T cells by coexpression of a soluble PD1-CH3 fusion protein.
Author: Pan, Zeyan|Di, Shengmeng|Shi, Bizhi|Jiang, Hua|Shi, Zhimin|Liu, Ying|Wang, Yi|Luo, Hong|Yu, Min|Wu, Xiuqi|Li, Zonghai
PMID: 30078052
Journal: Nanomedicine (Lond). 2018 Aug 9.
Title: Novel GPC3-binding WS2-Ga(3+)-PEG-peptide nanosheets for in vivo bimodal imaging-guided photothermal therapy.
Author: Song, Xiaodong|Shang, Wenting|Peng, Li|Jiang, Hongmei|Wang, Kun|Fang, Chihua|Tian, Jie
PMID: 30091395
Journal: Int J Nanomedicine. 2018 Aug 1;13:4433-4443.
Title: A GPC3-specific aptamer-mediated magnetic resonance probe for hepatocellular carcinoma.
Author: Zhao, Menglong|Liu, Zhuang|Dong, Lili|Zhou, Hongxin|Yang, Shuohui|Wu, Weizhong|Lin, Jiang
PMID: 30122918
Journal: Onco Targets Ther. 2018 Aug 10;11:4785-4795.
Title: Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro.
Author: Tian, Yuhang|Liu, Zhao|Zhang, Lei|Zhang, Jia|Han, Xue|Wang, Qiucheng|Cheng, Wen
PMID: 30127626
Journal: Contrast Media Mol Imaging. 2018 Sep 10;2018:9169072.
Title: Detecting GPC3-Expressing Hepatocellular Carcinoma with L5 Peptide-Guided Pretargeting Approach: In Vitro and In Vivo MR Imaging Experiments.
Author: Li, Weiyue|Xiao, Xiang|Li, Xiaodan|Xu, Yikai|Ma, Lichao|Guo, Liuji|Yan, Chenggong|Wu, Yuankui
PMID: 30275801
Journal: J Pak Med Assoc. 2018 Jul;68(7):1029-1031.
Title: Diagnostic accuracy of glypican-3 in differentiating hepatocellular carcinoma from metastatic liver tumours.
Author: Majeed, Sadia|Mushtaq, Sajid|Azam, Muhammad|Akhtar, Noreen|Hussain, Mudassar|Loya, Asif
PMID: 30317296
Journal: Front Pharmacol. 2018 Oct 1;9:1118.
Title: Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma.
Author: Guo, Xingliang|Jiang, Hua|Shi, Bizhi|Zhou, Min|Zhang, Honghong|Shi, Zhimin|Du, Guoxiu|Luo, Hong|Wu, Xiuqi|Wang, Yi|Sun, Ruixin|Li, Zonghai
PMID: 30327605
Journal: Mol Ther Nucleic Acids. 2018 Sep 27;13:376-386.
Title: Phosphorothioate-Modified AP613-1 Specifically Targets GPC3 when Used for Hepatocellular Carcinoma Cell Imaging.
Author: Dong, Lili|Zhou, Hongxin|Zhao, Menglong|Gao, Xinghui|Liu, Yang|Liu, Dongli|Guo, Wei|Hu, Hongwei|Xie, Qian|Fan, Jia|Lin, Jiang|Wu, Weizhong
PMID: 30347351
Journal: Hepatology. 2018 Oct 24.
Title: Glypican-3 Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.
Author: Fu, Ying|Urban, Daniel J|Nani, Roger R|Zhang, Yi-Fan|Li, Nan|Fu, Haiying|Shah, Hamzah|Gorka, Alexander P|Guha, Rajarshi|Chen, Lu|Hall, Matthew D|Schnermann, Martin J|Ho, Mitchell
PMID: 30353932
Journal: Appl Immunohistochem Mol Morphol. 2018 Oct 31.
Title: Glypican-3 and Hep Par-1 are Useful Biomarkers in the Cytologic Assessment of Ascites.
Author: Cabibi, Daniela|Bisanti, Andrea|Lanza, Dorotea|Brucculeri, Vanessa|Porcasi, Rossana|Ingrao, Sabrina|Midiri, Federico|Picone, Dario|Giannone, Antonino Giulio
PMID: 30383541