Primary Site >> Colorectal Cancer

Gene >> GNAS

Journal: Clin Cancer Res. 2005 Jul 15;11(14):5071-7.
Title: GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancer.
Author: Frey, Ulrich H|Alakus, Hakan|Wohlschlaeger, Jeremias|Schmitz, Klaus J|Winde, Gunther|van Calker, Hans G|Jockel, Karl-Heinz|Siffert, Winfried|Schmid, Kurt W
PMID: 16033819
Journal: Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):759-63.
Title: The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma.
Author: Frey, Ulrich H|Lummen, Gerd|Jager, Tobias|Jockel, Karl-Heinz|Schmid, Kurt W|Rubben, Herbert|Muller, Norbert|Siffert, Winfried|Eisenhardt, Andreas
PMID: 16467086
Journal: Breast Cancer Res Treat. 2007 Nov;105(3):311-7. Epub 2006 Dec 21.
Title: The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma.
Author: Otterbach, Friedrich|Callies, Rainer|Frey, Ulrich H|Schmitz, Klaus J|Wreczycki, Christof|Kimmig, Rainer|Siffert, Winfried|Schmid, Kurt W
PMID: 17186357
Journal: PLoS One. 2010 Jan 26;5(1):e8879.
Title: Distinct genetic alterations in colorectal cancer.
Author: Ashktorab, Hassan|Schaffer, Alejandro A|Daremipouran, Mohammad|Smoot, Duane T|Lee, Edward|Brim, Hassan
PMID: 20126641
Journal: Cancer Genet Cytogenet. 2010 Oct 1;202(1):67-9.
Title: Analysis of the frequency of GNAS codon 201 mutations in advanced colorectal cancer.
Author: Idziaszczyk, S|Wilson, C H|Smith, C G|Adams, D J|Cheadle, J P
PMID: 20804925
Journal: Int J Cancer. 2012 Feb 15;130(4):837-46.
Title: Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Author: Middeldorp, A|van Eijk, R|Oosting, J|Forte, G I|van Puijenbroek, M|van Nieuwenhuizen, M|Corver, W E|Ruano, D|Caldes, T|Wijnen, J|Morreau, H|van Wezel, T
PMID: 21445971
Journal: Br J Cancer. 2013 Mar 5;108(4):951-8.
Title: Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.
Author: Nishikawa, G|Sekine, S|Ogawa, R|Matsubara, A|Mori, T|Taniguchi, H|Kushima, R|Hiraoka, N|Tsuta, K|Tsuda, H|Kanai, Y
PMID: 23403822
Journal: PLoS One. 2014 Jan 30;9(1):e87966.
Title: GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers.
Author: Fecteau, Ryan E|Lutterbaugh, James|Markowitz, Sanford D|Willis, Joseph|Guda, Kishore
PMID: 24498230
Journal: Folia Histochem Cytobiol. 2014;52(2):90-5.
Title: GNAS1 mutation analysis in gastrointestinal tumors.
Author: Walther, Bernhard Maria|Walther, Ina|Chen, Yuan|Petersen, Iver
PMID: 25007176
Journal: Genome Med. 2014 May 29;6(5):43.
Title: Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Author: Alakus, Hakan|Babicky, Michele L|Ghosh, Pradipta|Yost, Shawn|Jepsen, Kristen|Dai, Yang|Arias, Angelo|Samuels, Michael L|Mose, Evangeline S|Schwab, Richard B|Peterson, Michael R|Lowy, Andrew M|Frazer, Kelly A|Harismendy, Olivier
PMID: 24944587
Journal: Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title: The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author: Abdul-Jalil, Khairun I|Sheehan, Katherine M|Toomey, Sinead|Schmid, Jasmin|Prehn, Jochen|O'Grady, Anthony|Cummins, Robert|O'Neill, Brian|McNamara, Deborah A|Deasy, Joseph|Breathnach, Oscar|Grogan, Liam|Rogers, Ailin|Doherty, Glen|Winter, Des|Ryan, John|El-
PMID: 24700299
Journal: PLoS One. 2014 Jan 27;9(1):e82185.
Title: An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Author: Brim, Hassan|Abu-Asab, Mones S|Nouraie, Mehdi|Salazar, Jose|Deleo, Jim|Razjouyan, Hadi|Mokarram, Pooneh|Schaffer, Alejandro A|Naghibhossaini, Fakhraddin|Ashktorab, Hassan
PMID: 24475022
Journal: Hum Pathol. 2015 Apr;46(4):507-13.
Title: Novel molecular insights from routine genotyping of colorectal carcinomas.
Author: Stachler, Matthew D|Rinehart, Elizabeth|Lindeman, Neal|Odze, Robert|Srivastava, Amitabh
PMID: 25683705
Journal: World J Gastroenterol. 2015 Jun 7;21(21):6470-8.
Title: Different treatment strategies and molecular features between right-sided and left-sided colon cancers.
Author: Shen, Hong|Yang, Jiao|Huang, Qing|Jiang, Meng-Jie|Tan, Yi-Nuo|Fu, Jian-Fei|Zhu, Li-Zhen|Fang, Xue-Feng|Yuan, Ying
PMID: 26074686
Journal: Arch Pathol Lab Med. 2016 Jun;140(6):529-35.
Title: Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas.
Author: Crumley, Suzanne M|Pepper, Kristi L|Phan, Alexandria T|Olsen, Randall J|Schwartz, Mary R|Portier, Bryce P
PMID: 26536055
Journal: BMC Med Genet. 2016 Dec 9;17(1):94.
Title: Pseudomyxoma peritonei of a mature ovarian teratoma caused by mismatch repair deficiency in a patient with Lynch syndrome: a case report.
Author: Gohda, Yoshimasa|Noguchi, Rei|Horie, Tomoko|Igari, Toru|Nakamura, Harumi|Ohta, Yasunori|Yamaguchi, Kiyoshi|Ikenoue, Tsuneo|Hatakeyama, Seira|Yusa, Nozomi|Furukawa, Yoichi|Yano, Hideaki
PMID: 27938333
Journal: Mol Cancer. 2016 Oct 18;15(1):63.
Title: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author: Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke
PMID: 27756406
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: J Transl Med. 2016 May 6;14(1):125.
Title: GNAS mutations as prognostic biomarker in patients with relapsed peritoneal pseudomyxoma receiving metronomic capecitabine and bevacizumab: a clinical and translational study.
Author: Pietrantonio, Filippo|Berenato, Rosa|Maggi, Claudia|Caporale, Marta|Milione, Massimo|Perrone, Federica|Tamborini, Elena|Baratti, Dario|Kusamura, Shigeki|Mariani, Luigi|Niger, Monica|Mennitto, Alessia|Gloghini, Annunziata|Bossi, Ilaria|Settanni, Giulio|Bus
PMID: 27154293
Journal: Tumori. 2017 Mar 24;103(2):209-211.
Title: Absence of GNAS mutation in colorectal carcinogenesis.
Author: Lee, Hyunsu|La, Boo-Mi|Hwang, IlSeon|Kang, Yu-Na|Choi, In-Jang|Lee, Jae-Ho
PMID: 26350188
Journal: Oncotarget. 2017 Jan 24;8(4):6579-6588.
Title: Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Author: Lee, Sung Hak|Jung, Seung Hyun|Kim, Tae-Min|Rhee, Je-Keun|Park, Hyeon-Chun|Kim, Min Sung|Kim, Sung Soo|An, Chang Hyeok|Lee, Sug Hyung|Chung, Yeun-Jun
PMID: 28179590
Journal: J Gastrointest Oncol. 2017 Feb;8(1):164-172.
Title: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
Author: Borazanci, Erkut|Millis, Sherri Z|Kimbrough, Jeffery|Doll, Nancy|Von Hoff, Daniel|Ramanathan, Ramesh K
PMID: 28280620
Journal: PLoS One. 2017 Jul 27;12(7):e0180616.
Title: Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer.
Author: Makondi, Precious Takondwa|Chu, Chi-Ming|Wei, Po-Li|Chang, Yu-Jia
PMID: 28749961
Journal: Oncotarget. 2017 Aug 21;8(42):72352-72362.
Title: Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer.
Author: Chang, Pi-Yueh|Chen, Jinn-Shiun|Chang, Shih-Cheng|Wang, Mei-Chia|Chang, Nai-Chung|Wen, Ying-Hao|Tsai, Wen-Sy|Liu, Wei-Hsiu|Liu, Hsiu-Ling|Lu, Jang-Jih
PMID: 29069792
Journal: Clin Cancer Res. 2018 Mar 1;24(5):1062-1072.
Title: Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes.
Author: Loree, Jonathan M|Pereira, Allan A L|Lam, Michael|Willauer, Alexandra N|Raghav, Kanwal|Dasari, Arvind|Morris, Van K|Advani, Shailesh|Menter, David G|Eng, Cathy|Shaw, Kenna|Broaddus, Russell|Routbort, Mark J|Liu, Yusha|Morris, Jeffrey S|Luthra, Rajyalakshm
PMID: 29180604
Journal: Oncotarget. 2018 May 22;9(39):25557-25571.
Title: Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - a preliminary report.
Author: Shiao, S Pamela K|Xiao, Haiyan|Dong, Lixin|Wang, Xiaoling|Liu, Kebin|She, Jinxiong|Shi, Huidong
PMID: 29876008
Journal: Lancet Gastroenterol Hepatol. 2018 Sep;3(9):635-643.
Title: Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.
Author: Domingo, Enric|Camps, Carme|Kaisaki, Pamela J|Parsons, Marie J|Mouradov, Dmitri|Pentony, Melissa M|Makino, Seiko|Palmieri, Michelle|Ward, Robyn L|Hawkins, Nicholas J|Gibbs, Peter|Askautrud, Hanne|Oukrif, Dahmane|Wang, Haitao|Wood, Joe|Tomlinson, Evie|Bark
PMID: 30042065
Journal: Clin Colorectal Cancer. 2018 Jul 17. pii: S1533-0028(18)30133-6.
Title: Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics.
Author: Khan, Maliha|Loree, Jonathan M|Advani, Shailesh M|Ning, Jing|Li, Wen|Pereira, Allan A L|Lam, Michael|Raghav, Kanwal|Morris, Van K|Broaddus, Russell|Maru, Dipen|Overman, Michael J|Kopetz, Scott
PMID: 30205948