Primary Site >> Colorectal Cancer

Gene >> GJA1

Journal: Hum Gene Ther. 1998 Oct 10;9(15):2253-61.
Title: Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation.
Author: McMasters, R A|Saylors, R L|Jones, K E|Hendrix, M E|Moyer, M P|Drake, R R
PMID: 9794209
Journal: Zhonghua Yi Xue Za Zhi (Taipei). 2000 Feb;63(2):131-7.
Title: Lymph node revealing solution and traditional 10% buffered formaldehyde for detecting lymph nodes in colorectal carcinoma.
Author: Jan, Y J|Huang, P C|Chen, J T|Ho, W L
PMID: 10677924
Journal: Am J Pathol. 2002 Apr;160(4):1229-38.
Title: Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas.
Author: Zhai, Yali|Wu, Rong|Schwartz, Donald R|Darrah, Danielle|Reed, Heather|Kolligs, Frank T|Nieman, Marvin T|Fearon, Eric R|Cho, Kathleen R
PMID: 11943708
Journal: Carcinogenesis. 2003 Apr;24(4):643-50.
Title: Cells heterozygous for the ApcMin mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization.
Author: Husoy, Trine|Cruciani, Veronique|Knutsen, Helle K|Mikalsen, Svein-Ole|Olstorn, Hege B|Alexander, Jan
PMID: 12727791
Journal: Int Surg. 2003 Jan-Mar;88(1):41-6.
Title: Carcinoid tumor in a Meckel's diverticulum: hypothesis on mutual embryological origin.
Author: Grossmann, Irene|Akkersdijk, George J M
PMID: 12731730
Journal: Ai Zheng. 2003 Jul;22(7):686-90.
Title: [In situ expression of connexins in various carcinomas].
Author: Fan, Song-Qing|Zhou, Ming|Xiang, Qiu|Wang, Jie-Ru|Xiong, Wei|Wang, Rong|Wei, Qi-You|Zhou, Jin-Ping|Li, Gui-Yuan
PMID: 12866956
Journal: Mol Carcinog. 2004 Apr;39(4):221-33.
Title: The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells.
Author: Ignatenko, Natalia A|Zhang, Hui|Watts, George S|Skovan, Bethany A|Stringer, David E|Gerner, Eugene W
PMID: 15057874
Journal: Oncology. 2005;68(2-3):217-22.
Title: Alterations in connexin26 expression during colorectal carcinogenesis.
Author: Kanczuga-Koda, Luiza|Sulkowski, Stanislaw|Koda, Mariusz|Sulkowska, Mariola
PMID: 16015037
Journal: Cancer Res. 2005 Dec 15;65(24):11361-6.
Title: CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
Author: Kemp, Zoe|Rowan, Andrew|Chambers, William|Wortham, Noel|Halford, Sarah|Sieber, Oliver|Mortensen, Neil|von Herbay, Axel|Gunther, Thomas|Ilyas, Mohammad|Tomlinson, Ian
PMID: 16357143
Journal: In Vivo. 2010 Jan-Feb;24(1):101-7.
Title: Gradual loss of functional gap junction within progression of colorectal cancer -- a shift from membranous CX32 and CX43 expression to cytoplasmic pattern during colorectal carcinogenesis.
Author: Kanczuga-Koda, Luiza|Koda, Mariusz|Sulkowski, Stanislaw|Wincewicz, Andrzej|Zalewski, Bogdan|Sulkowska, Mariola
PMID: 20133984
Journal: Epigenetics. 2011 May;6(5):602-9. Epub 2011 May 1.
Title: DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer.
Author: Sirnes, Solveig|Honne, Hilde|Ahmed, Deeqa|Danielsen, Stine Aske|Rognum, Torleiv O|Meling, Gunn Iren|Leithe, Edward|Rivedal, Edgar|Lothe, Ragnhild A|Lind, Guro E
PMID: 21406965
Journal: Gastroenterol Res Pract. 2011;2011:561719.
Title: Connexin43 Expression Increases in the Epithelium and Stroma along the Colonic Neoplastic Progression Pathway: Implications for Its Oncogenic Role.
Author: Han, Yusheng|Zhang, Paul J|Chen, Terina|Yum, Sabrina W|Pasha, Teresa|Furth, Emma E
PMID: 21754925
Journal: Int J Cancer. 2012 Aug 1;131(3):570-81.
Title: Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome.
Author: Sirnes, Solveig|Bruun, Jarle|Kolberg, Matthias|Kjenseth, Ane|Lind, Guro E|Svindland, Aud|Brech, Andreas|Nesbakken, Arild|Lothe, Ragnhild A|Leithe, Edward|Rivedal, Edgar
PMID: 21866551
Journal: Chin Med J (Engl). 2012 Oct;125(20):3640-5.
Title: Folfox4 regimen administered through combined hepatic arterial and systemic infusion for treatment of colorectal cancer with unresectable liver metastases.
Author: Guan, Mei|Chen, Shu-Chang|Ying, Hong-Yan|Zhao, Lin|Li, Xiao-Yuan|Zhou, Jian-Feng|Shao, Ya-Juan|Yang, Xian-da|Lin, Yi|Ning, Xiao-Hong|Bai, Chun-Mei
PMID: 23075717
Journal: Hepatogastroenterology. 2013 Jul-Aug;60(125):1053-7.
Title: Comparison of primarily diet-modifiable intestinal factors, connexin 43 and E-cadherin with TP53 and TGFB1 in colorectal cancer.
Author: Wincewicz, Andrzej|Urbaniak-Wasik, Sawka|Woltanowska, Martyna|Sulkowska, Urszula|Koda, Mariusz|Kanczuga-Koda, Luiza|Sulkowski, Stanisaw|Zamenhof, Pierre Lebard|Lewitowicz, Piotr|Koziel, Dorota|Gluszek, Stanisaw
PMID: 23803369
Journal: Microrna. 2014;2(3):219-24.
Title: Mutations in MicroRNA Genes and Their Binding Sites are Infrequently Associated with Human Colorectal Cancer in the Kashmiri Population.
Author: Maqbool, Raihana|Ismail, Rehana|Hussain, Mahboob- Ul-
PMID: 25069446
Journal: Zhonghua Bing Li Xue Za Zhi. 2014 May;43(5):330-3.
Title: [Establishment of a two-layer cell spheroid model and its applications in colorectal tumor cell-fibroblast interactions with effect on Cx43 expression].
Author: Zhao, Zhimin|Lin, Shanli|Wen, Huan|Deng, Hong
PMID: 25030867
Journal: BMC Cancer. 2014 Jul 9;14:502.
Title: Increase of gap junction activities in SW480 human colorectal cancer cells.
Author: Bigelow, Kristina|Nguyen, Thu A
PMID: 25008544
Journal: Asian Pac J Cancer Prev. 2014;15(7):2987-91.
Title: Pathological implications of Cx43 down-regulation in human colon cancer.
Author: Ismail, Rehana|Rashid, Rabiya|Andrabi, Khurshid|Parray, Fazl Q|Besina, Syed|Shah, Mohd Amin|Ul Hussain, Mahboob
PMID: 24815435
Journal: Oncol Lett. 2014 Jun;7(6):1863-1870.
Title: E-cadherin and beta-catenin adhesion proteins correlate positively with connexins in colorectal cancer.
Author: Kanczuga-Koda, Luiza|Wincewicz, Andrzej|Fudala, Andrzej|Abrycki, Tomasz|Famulski, Waldemar|Baltaziak, Marek|Sulkowski, Stanislaw|Koda, Mariusz
PMID: 24932249
Journal: Int J Cancer. 2015 Jul 1;137(1):1-11.
Title: Connexins in colorectal cancer pathogenesis.
Author: Sirnes, Solveig|Lind, Guro E|Bruun, Jarle|Fykerud, Tone A|Mesnil, Marc|Lothe, Ragnhild A|Rivedal, Edgar|Kolberg, Matthias|Leithe, Edward
PMID: 24752574
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1666-73. eCollection 2015.
Title: Synergistic effects of AKAP95, Cyclin D1, Cyclin E1, and Cx43 in the development of rectal cancer.
Author: Qi, Fengjie|Yuan, Yangyang|Zhi, Xuehong|Huang, Qian|Chen, Yuexin|Zhuang, Wenxin|Zhang, Dengcheng|Teng, Bogang|Kong, Xiangyu|Zhang, Yongxing
PMID: 25973052
Journal: Oncotarget. 2015 Oct 6;6(30):28800-15.
Title: Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells.
Author: Thuringer, Dominique|Berthenet, Kevin|Cronier, Laurent|Solary, Eric|Garrido, Carmen
PMID: 26320187
Journal: Int J Surg Case Rep. 2016;27:51-54.
Title: Odd localisation for a gastric cancer histology.
Author: Kuczma, Paulina|Vidal Fortuny, Jordi|Essia, Saiji|de Lassus, Ariane|Morel, Philippe|Ris, Frederic
PMID: 27543724
Journal: Anticancer Res. 2016 Oct;36(10):5437-5442.
Title: CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential.
Author: Biscanin, Alen|Ljubicic, Neven|Boban, Marko|Balicevic, Drinko|Pavic, Ivana|Biscanin, Mirela Maver|Budimir, Ivan|Dorosulic, Zdravko|Duvnjak, Marko
PMID: 27798912
Journal: Mol Med Rep. 2016 Nov;14(5):4893-4900.
Title: Gap junction composed of connexin43 modulates 5fluorouracil, oxaliplatin and irinotecan resistance on colorectal cancers.
Author: Zou, Zhao-Wei|Chen, Hai-Jin|Yu, Jin-Long|Huang, Zong-Hai|Fang, Shun|Lin, Xiao-Hua
PMID: 27748862
Journal: Anticancer Res. 2016 May;36(5):2189-96.
Title: Connexin 43 Expression in Primary Colorectal Carcinomas in Patients with Stage III and IV Disease.
Author: Radic, Jasna|Kruslin, Bozo|Samija, Mirko|Ulamec, Monika|Milosevic, Milan|Jazvic, Marijana|Samija, Ivan|Grah, Josip Joachim|Bolanca, Ante|Kusic, Zvonko
PMID: 27127122
Journal: Oncotarget. 2016 May 10;7(19):28160-8.
Title: Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis.
Author: Thuringer, Dominique|Jego, Gaetan|Berthenet, Kevin|Hammann, Arlette|Solary, Eric|Garrido, Carmen
PMID: 27058413
Journal: Mol Biosyst. 2016 Jan;12(1):93-101.
Title: A deterministic oscillatory model of microtubule growth and shrinkage for differential actions of short chain fatty acids.
Author: Kilner, Josephine|Corfe, Bernard M|McAuley, Mark T|Wilkinson, Stephen J
PMID: 26562762
Journal: JCI Insight. 2017 Jan 12;2(1):e91419.
Title: Metastasis regulation by PPARD expression in cancer cells.
Author: Zuo, Xiangsheng|Xu, Weiguo|Xu, Min|Tian, Rui|Moussalli, Micheline J|Mao, Fei|Zheng, Xiaofeng|Wang, Jing|Morris, Jeffrey S|Gagea, Mihai|Eng, Cathy|Kopetz, Scott|Maru, Dipen M|Rashid, Asif|Broaddus, Russell|Wei, Daoyan|Hung, Mien-Chie|Sood, Anil K|Shureiqi,
PMID: 28097239
Journal: Mol Med Rep. 2017 Jul;16(1):943-948.
Title: Sufentanil attenuates oxaliplatin cytotoxicity via inhibiting connexin 43composed gap junction function.
Author: Zhang, Qi|Su, Min
PMID: 28586033
Journal: Exp Ther Med. 2017 Aug;14(2):1212-1218.
Title: Connexin 43 enhances paclitaxel cytotoxicity in colorectal cancer cell lines.
Author: Wang, Siqi|Zhang, Shiwu|Zhao, Zhenying|Zhang, Chunze|Yang, Xiaoyun|Wang, Yijia
PMID: 28810580
Journal: Oncol Lett. 2017 Sep;14(3):3669-3674.
Title: Deficiency of gap junction composed of connexin43 contributes to oxaliplatin resistance in colon cancer cells.
Author: Su, Min|Zhang, Qi
PMID: 28927129
Journal: Int J Colorectal Dis. 2018 Mar;33(3):273-283.
Title: Effect of immunonutrition on colorectal cancer patients undergoing surgery: a meta-analysis.
Author: Xu, Jing|Sun, Xian|Xin, Qianqian|Cheng, Ying|Zhan, Zhen|Zhang, Junfeng|Wu, Juan
PMID: 29335838
Journal: Int J Colorectal Dis. 2018 Apr;33(4):403-409.
Title: Extra nodular metastasis is a poor prognostic factor for overall survival in node-positive patients with colorectal cancer.
Author: Ambe, Peter C|Godde, Daniel|Storkel, Stephan|Zirngibl, Hubert|Bonicke, Lars
PMID: 29520454