Primary Site >> Pancreatic Cancer

Gene >> GGT1

Journal: Dig Dis Sci. 1980 May;25(5):374-8.
Title: Pancreatic juice gamma-glutamyltransferase, alanine transaminase, and alkaline phosphatase in pancreatic disease.
Author: Carr-Locke, D L|Davies, T J
PMID: 6102899
Journal: Biochem Biophys Res Commun. 1986 Oct 15;140(1):167-73.
Title: Establishment of a human pancreatic adenocarcinoma cell line (PSN-1) with amplifications of both c-myc and activated c-Ki-ras by a point mutation.
Author: Yamada, H|Yoshida, T|Sakamoto, H|Terada, M|Sugimura, T
PMID: 3778442
Journal: Jpn J Cancer Res. 1989 Jul;80(7):622-6.
Title: Frequency and types of point mutation at the 12th codon of the c-Ki-ras gene found in pancreatic cancers from Japanese patients.
Author: Mariyama, M|Kishi, K|Nakamura, K|Obata, H|Nishimura, S
PMID: 2507485
Journal: Mol Carcinog. 1990;3(5):296-301.
Title: Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.
Author: Fujii, H|Egami, H|Chaney, W|Pour, P|Pelling, J
PMID: 2173932
Journal: Tumori. 1991 Feb 28;77(1):56-60.
Title: Comparison of two newly identified tumor markers (CAR-3 and DU-PAN-2) with CA 19-9 in patients with pancreatic cancer.
Author: Ferrara, C|Basso, D|Fabris, C|Malesci, A|Fogar, P|Meggiato, T|Panozzo, M P|Scalon, P|Del Favero, G|Plebani, M
PMID: 1673269
Journal: Nihon Geka Gakkai Zasshi. 1991 Apr;92(4):453-8.
Title: [Detection of point mutation of Kirsten ras oncogene in pancreatic carcinoma by polymerase chain reaction].
Author: Motojima, K|Kohara, N|Furui, J|Terada, M|Tsunoda, T|Nagata, Y|Urano, K
PMID: 1870574
Journal: Jpn J Cancer Res. 1991 Oct;82(10):1057-60.
Title: c-Ki-ras point mutations in ductectatic-type mucinous cystic neoplasms of the pancreas.
Author: Yanagisawa, A|Kato, Y|Ohtake, K|Kitagawa, T|Ohashi, K|Hori, M|Takagi, K|Sugano, H
PMID: 1955373
Journal: Am J Gastroenterol. 1991 Dec;86(12):1784-8.
Title: Mutations in the Kirsten-ras oncogene are common but lack correlation with prognosis and tumor stage in human pancreatic carcinoma.
Author: Motojima, K|Urano, T|Nagata, Y|Shiku, H|Tsunoda, T|Kanematsu, T
PMID: 1962623
Journal: Orv Hetil. 1992 May 24;133(21):1301-4, 1307.
Title: [Diagnostic value of CA 19-9 and CEA in gastrointestinal pathology].
Author: Patai, A|Heber, S|Dobronte, Z|Kovacs, L G
PMID: 1603581
Journal: Carcinogenesis. 1993 May;14(5):1027-33.
Title: Neoplastic transformation of propagable cultured rat pancreatic duct epithelial cells by azaserine and streptozotocin.
Author: Shepherd, J G|Chen, J R|Tsao, M S|Duguid, W P
PMID: 8099312
Journal: Int J Pancreatol. 1993 Dec;14(3):237-44.
Title: The role of Ras mutation in pancreatic cancer, precancerous lesions, and chronic pancreatitis.
Author: Tabata, T|Fujimori, T|Maeda, S|Yamamoto, M|Saitoh, Y
PMID: 8113625
Journal: Pancreas. 1994 Sep;9(5):657-61.
Title: Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation.
Author: Sumi, S|Beauchamp, R D|Townsend, C M Jr|Pour, P M|Ishizuka, J|Thompson, J C
PMID: 7809022
Journal: Int J Cancer. 1994 Apr 15;57(2):167-71.
Title: Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences.
Author: Scarpa, A|Capelli, P|Villaneuva, A|Zamboni, G|Lluis, F|Accolla, R|Mariuzzi, G|Capella, G
PMID: 8157353
Journal: Nihon Rinsho. 1995 Feb;53(2):511-7.
Title: [Mutation of the K-ras oncogene in pancreatic carcinoma, and application of its detection in pancreatic juice to diagnose pancreatic carcinoma].
Author: Sawabu, N|Watanabe, H|Yamaguchi, Y|Okai, T
PMID: 7699881
Journal: Mutat Res. 1995 Mar;327(1-2):151-60.
Title: Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin.
Author: Fowler, M L|Sigler, R E|de la Iglesia, F A|Reddy, J K|Lalwani, N D
PMID: 7870083
Journal: Am J Gastroenterol. 1996 Aug;91(8):1616-21.
Title: Diagnosis of pancreatic cancer by K-ras point mutation and cytology of pancreatic juice.
Author: Uehara, H|Nakaizumi, A|Baba, M|Iishi, H|Tatsuta, M|Kitamura, T|Ohigashi, H|Ishikawa, O|Takenaka, A|Ishiguro, S
PMID: 8759672
Journal: Am J Gastroenterol. 1996 Sep;91(9):1848-51.
Title: Detection of K-ras point mutation at codon 12 in pure pancreatic juice collected 3 years and 6 months before the clinical diagnosis of pancreatic cancer.
Author: Wakabayashi, T|Sawabu, N|Watanabe, H|Morimoto, H|Sugioka, G|Takita, Y
PMID: 8792713
Journal: Int J Radiat Oncol Biol Phys. 1996 Jan 1;34(1):161-6.
Title: C-Ki-ras mutations in peripheral blood of pancreatic cancer patients: a marker for early tumor metastasis.
Author: Mohiuddin, M|Ahmed, M M|Venkatasubbarao, K
PMID: 12118546
Journal: Cancer. 1998 May 15;82(10):1839-49.
Title: Histologic and biologic patterns of microscopic pancreatic ductal adenocarcinomas detected incidentally at autopsy.
Author: Kimura, W|Morikane, K|Esaki, Y|Chan, W C|Pour, P M
PMID: 9587115
Journal: Histopathology. 1998 May;32(5):444-8.
Title: Clear cell carcinoma of the pancreas: an adenocarcinoma with ductal phenotype.
Author: Luttges, J|Vogel, I|Menke, M|Henne-Bruns, D|Kremer, B|Kloppel, G
PMID: 9639120
Journal: Clin Chem Lab Med. 1998 Aug;36(8):593-5.
Title: Restriction digest PCR (RD-PCR) for the analysis of gene mutations. Application to Ki-ras.
Author: Huber, K R|Bittner, J|Bauer, K|Trumper, L|Sek, A|Sebesta, C|Rosen, H|Tragl, K H
PMID: 9806467
Journal: Clin Chim Acta. 1998 Oct;277(2):181-9.
Title: Portal but not peripheral serum levels of interleukin 6 could interfere with glucose metabolism in patients with pancreatic cancer.
Author: Fogar, P|Basso, D|Pasquali, C|Piva, M G|Brigato, L|De Paoli, M|Galeotti, F|Corsini, A|Plebani, M
PMID: 9853701
Journal: J Clin Gastroenterol. 1998 Dec;27(4):357-60.
Title: Pancreatic cancer associated with granulocyte-colony stimulating factor production confirmed by immunohistochemistry.
Author: Ohtsubo, K|Mouri, H|Sakai, J|Akasofu, M|Yamaguchi, Y|Watanabe, H|Gabata, T|Motoo, Y|Okai, T|Sawabu, N
PMID: 9855271
Journal: Eur J Gastroenterol Hepatol. 1998 Dec;10(12):1025-9.
Title: Analysis of K-ras gene mutations in rare pancreatic and ampullary tumours.
Author: Ebert, M P|Hoffmann, J|Schneider-Stock, R|Kasper, H U|Schulz, H U|Lippert, H|Roessner, A|Malfertheiner, P
PMID: 9895049
Journal: Virchows Arch. 1999 Nov;435(5):461-8.
Title: Duct changes and K-ras mutations in the disease-free pancreas: analysis of type, age relation and spatial distribution.
Author: Luttges, J|Reinecke-Luthge, A|Mollmann, B|Menke, M A|Clemens, A|Klimpfinger, M|Sipos, B|Kloppel, G
PMID: 10592048
Journal: Carcinogenesis. 1999 Feb;20(2):317-24.
Title: Induction of adenocarcinoma from hamster pancreatic islet cells treated with N-nitrosobis(2-oxopropyl)amine in vitro.
Author: Schmied, B|Liu, G|Moyer, M P|Hernberg, I S|Sanger, W|Batra, S|Pour, P M
PMID: 10069471
Journal: Pancreas. 1999 Nov;19(4):353-61.
Title: Clonal preservation of human pancreatic cell line derived from primary pancreatic adenocarcinoma.
Author: Mohammad, R M|Li, Y|Mohamed, A N|Pettit, G R|Adsay, V|Vaitkevicius, V K|Al-Katib, A M|Sarkar, F H
PMID: 10547195
Journal: Cancer Gene Ther. 2000 Mar;7(3):373-83.
Title: Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma.
Author: Tsuchida, T|Kijima, H|Hori, S|Oshika, Y|Tokunaga, T|Kawai, K|Yamazaki, H|Ueyama, Y|Scanlon, K J|Tamaoki, N|Nakamura, M
PMID: 10766343
Journal: Arq Gastroenterol. 2000 Jul-Sep;37(3):183-6.
Title: [Laparoscopic treatment of common bile duct lithiasis].
Author: Machado, M A|da Rocha, J R|Herman, P|Montagnini, A L|Machado, M C
PMID: 11236272
Journal: Pathol Int. 2001 Jul;51(7):549-54.
Title: Adenocarcinoma arising in gastric heterotopic pancreas: clinicopathological and immunohistochemical study with genetic analysis of a case.
Author: Osanai, M|Miyokawa, N|Tamaki, T|Yonekawa, M|Kawamura, A|Sawada, N
PMID: 11472568
Journal: Indian J Clin Biochem. 2001 Jan;16(1):60-4.
Title: Leucine amino peptidase a better indicator of carcinoma of liver, biliary tract and pancreas.
Author: Ghadge, M S|Sirsat, A V|Bhansali, M S|Desouza, L J|Jagannath, P
PMID: 23105293
Journal: Carcinogenesis. 2002 Jan;23(1):101-6.
Title: Occupational exposure to organic solvents and K-ras mutations in exocrine pancreatic cancer.
Author: Alguacil, Juan|Porta, Miquel|Malats, Nuria|Kauppinen, Timo|Kogevinas, Manolis|Benavides, Fernando G|Partanen, Timo|Carrato, Alfredo
PMID: 11756230
Journal: Jpn J Clin Oncol. 2002 Apr;32(4):146-51.
Title: Invasive ductal adenocarcinoma of the remnant pancreatic body 9 years after resection of an intraductal papillary-mucinous carcinoma of the pancreatic head: a case report and comparison of DNA sequence in K-ras gene mutation.
Author: Komori, Takamichi|Ishikawa, Osamu|Ohigashi, Hiroaki|Yamada, Terumasa|Sasaki, Yo|Imaoka, Shingi|Nakaizumi, Akihiko|Uehara, Hiroyuki|Tanaka, Sachiko|Mano, Yoshiyuki|Kasugai, Tsutomu
PMID: 12072425
Journal: Chin Med J (Engl). 2003 Oct;116(10):1585-7.
Title: Unique GGT --> GTT mutation at K-ras codon 12 in six human pancreatic cancer cell lines from Chinese patients.
Author: Wei, Shuanzeng|Liu, Tonghua|Liu, Hongrui|Gao, Jie
PMID: 14640107
Journal: Int J Oncol. 2004 Mar;24(3):559-64.
Title: Ribozyme against mutant K-ras mRNA suppresses tumor growth of pancreatic cancer.
Author: Kijima, Hiroshi|Yamazaki, Hitoshi|Nakamura, Masato|Scanlon, Kevin J|Osamura, R Yoshiyuki|Ueyama, Yoshito
PMID: 14767540
Journal: World J Gastroenterol. 2004 Mar 15;10(6):881-4.
Title: Detection of point mutation in K-ras oncogene at codon 12 in pancreatic diseases.
Author: Ren, Yue-Xin|Xu, Guo-Ming|Li, Zhao-Shen|Song, Yu-Gang
PMID: 15040037
Journal: Virchows Arch. 2005 Mar;446(3):239-45.
Title: Mucinous cystic carcinoma of the pancreas: a unique cell line and xenograft model of a preinvasive lesion.
Author: Sorio, Claudio|Capelli, Paola|Lissandrini, Daniele|Moore, Patrick S|Balzarini, Piera|Falconi, Massimo|Zamboni, Giuseppe|Scarpa, Aldo
PMID: 15688169
Journal: Ai Zheng. 2005 May;24(5):559-62.
Title: [Anti-pancreatic cancer immune response induced by K-ras mutated peptide].
Author: He, Yang|Yang, Bo|Ruan, Chang-Geng
PMID: 15890097
Journal: South Med J. 2006 Mar;99(3):306-8.
Title: Patient with markedly elevated CA 19-9 not associated with malignancy.
Author: Lowe, Douglas|Lee, Jeffrey|Schade, Robert|Chaudhary, Ayaz
PMID: 16553110
Journal: HPB (Oxford). 2007;9(1):16-25.
Title: Adenoviral p53 gene transfer and gemcitabine in three patients with liver metastases due to advanced pancreatic carcinoma.
Author: Wolkersdorfer, Gernot W|Thiede, Christian|Fischer, Rainer|Ehninger, Gerhard|Haag, Cornelie
PMID: 18333108
Journal: Cancer Biol Ther. 2008 Mar;7(3):353-360.
Title: Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection.
Author: Shi, Chanjuan|Fukushima, Noriyoshi|Abe, Tadayoshi|Bian, Yansong|Hua, Li|Wendelburg, Brian J|Yeo, Charles J|Hruban, Ralph H|Goggins, Michael G|Eshleman, James R
PMID: 18075308
Journal: Ai Zheng. 2008 May;27(5):496-504.
Title: [Combinational effects of K-ras and IGF-IR antisense oligodeoxynucleotide on proliferation and apoptosis of human pancreatic cancer Patu8988 cells].
Author: Shen, Yong-Mei|Yang, Xiao-Chun|Zhang, Mei-Hua|Shen, Jun-Kang|Sun, Yi-Hui
PMID: 18479599
Journal: World J Gastroenterol. 2008 Sep 7;14(33):5176-85.
Title: Enhanced therapeutic effects for human pancreatic cancer by application K-ras and IGF-IR antisense oligodeoxynucleotides.
Author: Shen, Yong-Mei|Yang, Xiao-Chun|Yang, Chen|Shen, Jun-Kang
PMID: 18777594
Journal: Pancreatology. 2010;10(2-3):194-200.
Title: Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis.
Author: Diergaarde, Brenda|Brand, Randall|Lamb, Janette|Cheong, Soo Yeon|Stello, Kim|Barmada, M Michael|Feingold, Eleanor|Whitcomb, David C
PMID: 20484958
Journal: Zhonghua Bing Li Xue Za Zhi. 2011 Nov;40(11):754-7.
Title: [Colloid carcinoma of pancreas: a clinicopathologic study of 4 cases].
Author: Chang, Xiao-yan|Jiang, Ying|Li, Ji|Luo, Yu-feng|Cao, Jin-ling|Chen, Jie
PMID: 22336159
Journal: Pancreas. 2013 Mar;42(2):216-22.
Title: Genetic alterations of K-ras, p53, c-erbB-2, and DPC4 in pancreatic ductal adenocarcinoma and their correlation with patient survival.
Author: Shin, Sang Hyun|Kim, Song Cheol|Hong, Seung-Mo|Kim, Young Hoon|Song, Ki-Byung|Park, Kwang-Min|Lee, Young-Joo
PMID: 23344532
Journal: Pancreas. 2013 Jul;42(5):836-40.
Title: Variation in the gamma-glutamyltransferase 1 gene and risk of chronic pancreatitis.
Author: Brand, Harrison|Diergaarde, Brenda|O'Connell, Michael R|Whitcomb, David C|Brand, Randall E
PMID: 23462328
Journal: PLoS One. 2013;8(4):e60870.
Title: Somatic mutations in exocrine pancreatic tumors: association with patient survival.
Author: Rachakonda, P Sivaramakrishna|Bauer, Andrea S|Xie, Huaping|Campa, Daniele|Rizzato, Cosmeri|Canzian, Federico|Beghelli, Stefania|Greenhalf, William|Costello, Eithne|Schanne, Michaela|Heller, Anette|Scarpa, Aldo|Neoptolemos, John P|Werner, Jens|Buchler, Mar
PMID: 23565280
Journal: Metabolomics. 2014;10(1):91-104.
Title: Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells.
Author: Cantoria, Mary Jo|Boros, Laszlo G|Meuillet, Emmanuelle J
PMID: 24482631
Journal: Virchows Arch. 2015 Feb;466(2):237-41.
Title: Basaloid carcinoma of the pancreas--clinicopathological presentation and oncogenetic snapshot of a rare entity.
Author: Szasz, A Marcell|Szirtes, Ildiko|Tihanyi, Balazs|Barkaszi, Bernadett|Baranyai, Zsolt|Tihanyi, Tibor|Harsanyi, Laszlo|Timar, Jozsef|Kulka, Janina
PMID: 25432630
Journal: GE Port J Gastroenterol. 2015 Oct 29;22(6):234-239.
Title: Left-Sided Portal Hypertension: A Sinister Entity.
Author: Fernandes, Alexandra|Almeida, Nuno|Ferreira, Ana Margarida|Casela, Adriano|Gomes, Dario|Portela, Francisco|Camacho, Ernestina|Sofia, Carlos
PMID: 28868415
Journal: Oncotarget. 2017 Apr 21;8(33):54277-54284.
Title: Multi-modality imaging-monitored creation of rat orthotopic pancreatic head cancer with obstructive jaundice.
Author: Bai, Zhibin|Shi, Yaoping|Wang, Jianfeng|Qiu, Longhua|Teng, Gaojun|Zhang, Feng|Yang, Xiaoming
PMID: 28903340